acetaminophen glucuronide
| Title | Journal |
|---|---|
| Modulation of O-GlcNAc Levels in the Liver Impacts Acetaminophen-Induced Liver Injury by Affecting Protein Adduct Formation and Glutathione Synthesis. | Toxicological sciences : an official journal of the Society of Toxicology 20180401 |
| A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: Application to acetaminophen. | Toxicology and applied pharmacology 20160201 |
| Simultaneous LC-MS/MS quantitation of acetaminophen and its glucuronide and sulfate metabolites in human dried blood spot samples collected by subjects in a pilot clinical study. | Bioanalysis 20120601 |
| Investigating paracetamol pharmacokinetics using venous and capillary blood and saliva sampling. | The Journal of pharmacy and pharmacology 20120501 |
| Simultaneous quantitative determination of paracetamol and its glucuronide conjugate in human plasma and urine by liquid chromatography coupled to electrospray tandem mass spectrometry: application to a clinical pharmacokinetic study. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120415 |
| UDP-glucuronosyltransferase expression in mouse liver is increased in obesity- and fasting-induced steatosis. | Drug metabolism and disposition: the biological fate of chemicals 20120201 |
| Imitation of drug metabolism in human liver and cytotoxicity assay using a microfluidic device coupled to mass spectrometric detection. | Lab on a chip 20120107 |
| Pharmacokinetics and ocular disposition of paracetamol and paracetamol glucuronide in rabbits with diabetes mellitus induced by alloxan. | Pharmacological reports : PR 20120101 |
| The impact of Caesarean delivery on paracetamol and ketorolac pharmacokinetics: a paired analysis. | Journal of biomedicine & biotechnology 20120101 |
| Postprandial and fasting hepatic glucose fluxes in long-standing type 1 diabetes. | Diabetes 20110601 |
| Effects of imatinib mesylate on the pharmacokinetics of paracetamol (acetaminophen) in Korean patients with chronic myelogenous leukaemia. | British journal of clinical pharmacology 20110201 |
| Acetaminophen pharmacokinetics in children with nonalcoholic fatty liver disease. | Journal of pediatric gastroenterology and nutrition 20110201 |
| Pharmacokinetics of intravenous paracetamol in elderly patients. | Clinical pharmacokinetics 20110201 |
| Comparison of the pharmacokinetics of paracetamol from two generic products in patients after total gastric resection. | Pharmacological reports : PR 20110101 |
| Evaluating human liver reserve function by measuring serum concentrations of phenacetin and its metabolites. | Journal of digestive diseases 20101201 |
| Caco-2 cell monolayers as a tool to study simultaneous phase II metabolism and metabolite efflux of indomethacin, paracetamol and 1-naphthol. | International journal of pharmaceutics 20100104 |
| The effect of transcatheter arterial chemoembolization on phase II drug metabolism enzymes in patients with hepatocellular carcinoma. | Cancer chemotherapy and pharmacology 20100101 |
| Does rapid metabolism ensure negligible risk from bisphenol A? | Environmental health perspectives 20091101 |
| In vivo glucuronidation activity of drugs in neonates: extensive interindividual variability despite their young age. | Therapeutic drug monitoring 20090801 |
| Studies of acetaminophen and metabolites in urine and their correlations with toxicity using metabolomics. | Drug metabolism letters 20090801 |
| Additional evidence that transaldolase exchange, isotope discrimination during the triose-isomerase reaction, or both occur in humans: effects of type 2 diabetes. | Diabetes 20090701 |
| Simultaneous RP-HPLC determination of sotalol, metoprolol, alpha-hydroxymetoprolol, paracetamol and its glucuronide and sulfate metabolites in human urine. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090601 |
| Effect of repeated administration with subtoxic doses of acetaminophen to rats on enterohepatic recirculation of a subsequent toxic dose. | Biochemical pharmacology 20090515 |
| Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice. | Toxicological sciences : an official journal of the Society of Toxicology 20090501 |
| Simultaneous modelling of the Michaelis-Menten kinetics of paracetamol sulphation and glucuronidation. | Clinical and experimental pharmacology & physiology 20090101 |
| Effect of the acute phase response induced by endotoxin administration on the expression and activity of UGT isoforms in rats. | Drug metabolism letters 20081201 |
| Prandial insulin and the systemic appearance of meal-derived glucose in people with type 1 diabetes. | Diabetes care 20081101 |
| Sources of hepatic glucose production by 2H2O ingestion and Bayesian analysis of 2H glucuronide enrichment. | Magnetic resonance in medicine 20080901 |
| Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). | Journal of medicinal chemistry 20080612 |
| Development of an HPLC-MS/MS method for the selective determination of paracetamol metabolites in mouse urine. | Analytical biochemistry 20080301 |
| Hepatic synthesis and urinary elimination of acetaminophen glucuronide are exacerbated in bile duct-ligated rats. | Drug metabolism and disposition: the biological fate of chemicals 20080301 |
| Evidence that processes other than gluconeogenesis may influence the ratio of deuterium on the fifth and third carbons of glucose: implications for the use of 2H2O to measure gluconeogenesis in humans. | Diabetes 20080101 |
| Beneficial effect of spironolactone administration on ethynylestradiol-induced cholestasis in the rat: involvement of up-regulation of multidrug resistance-associated protein 2. | Drug metabolism and disposition: the biological fate of chemicals 20071101 |
| Monitoring paracetamol metabolism after single and repeated administration in pediatric patients with neoplastic diseases. | International journal of clinical pharmacology and therapeutics 20070901 |
| Expression of 25 human ABC transporters in the yeast Pichia pastoris and characterization of the purified ABCC3 ATPase activity. | Biochemistry 20070710 |
| Evidence for function of UDP galactose pyrophosphorylase in mice with absent galactose-1-phosphate uridyltransferase. | Molecular genetics and metabolism 20070601 |
| Urinary metabolites to assess in vivo ontogeny of hepatic drug metabolism in early neonatal life. | Methods and findings in experimental and clinical pharmacology 20070501 |
| Effects of combined UDP-glucuronosyltransferase (UGT) 1A1*28 and 1A6*2 on paracetamol pharmacokinetics in beta-thalassemia/HbE. | Pharmacology 20070101 |
| Glucuronidation in the chimpanzee (Pan troglodytes): studies with acetaminophen, oestradiol and morphine. | Xenobiotica; the fate of foreign compounds in biological systems 20061201 |
| A pharmacokinetic study of paracetamol in Thai beta-thalassemia/HbE patients. | European journal of clinical pharmacology 20060901 |
| Noninvasive analysis of hepatic glycogen kinetics before and after breakfast with deuterated water and acetaminophen. | Diabetes 20060801 |
| Identification of phenacetin metabolites in human urine after administration of phenacetin-C2H3: measurement of futile metabolic deacetylation via HPLC/MS-SPE-NMR and HPLC-ToF MS. | Xenobiotica; the fate of foreign compounds in biological systems 20060701 |
| Ethynylestradiol increases expression and activity of rat liver MRP3. | Drug metabolism and disposition: the biological fate of chemicals 20060601 |
| Pathways of galactose metabolism by galactosemics: evidence for galactose conversion to hepatic UDPglucose. | Molecular genetics and metabolism 20060201 |
| Comments on 'shift from biliary to urinary elimination of acetaminophen-glucuronide in acetaminophen-pretreated rats'. | The Journal of pharmacology and experimental therapeutics 20060201 |
| Global systems biology, personalized medicine and molecular epidemiology. | Molecular systems biology 20060101 |
| Altered disposition of acetaminophen in mice with a disruption of the Mrp3 gene. | Hepatology (Baltimore, Md.) 20051101 |
| Intra- and interindividual variability of glucuronidation of paracetamol during repeated administration of propacetamol in neonates. | Acta paediatrica (Oslo, Norway : 1992) 20050901 |
| Effect of taurine on biliary excretion and metabolism of acetaminophen in male hamsters. | Biological & pharmaceutical bulletin 20041101 |
| Glucose production pathways by 2H and 13C NMR in patients with HIV-associated lipoatrophy. | Magnetic resonance in medicine 20040401 |
| The quantification of paracetamol, paracetamol glucuronide and paracetamol sulphate in plasma and urine using a single high-performance liquid chromatography assay. | Journal of pharmaceutical and biomedical analysis 20040218 |
| Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites. | Drug metabolism and disposition: the biological fate of chemicals 20030901 |
| Higher insulin concentrations are required to suppress gluconeogenesis than glycogenolysis in nondiabetic humans. | Diabetes 20030901 |
| Paracetamol and metabolite pharmacokinetics in infants. | European journal of clinical pharmacology 20030701 |
| Hepatobiliary excretion of acetaminophen glutathione conjugate and its derivatives in transport-deficient (TR-) hyperbilirubinemic rats. | Drug metabolism and disposition: the biological fate of chemicals 20030601 |
| Transiently altered acetaminophen metabolism after liver transplantation. | Clinical pharmacology and therapeutics 20030601 |
| Analysis of acetaminophen glucuronide conjugate accompanied by adduct ion production by liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry. | Journal of pharmaceutical and biomedical analysis 20030115 |
| Noninvasive evaluation of liver metabolism by 2H and 13C NMR isotopomer analysis of human urine. | Analytical biochemistry 20030115 |
| Feasibility of atmospheric pressure desorption/ionization on silicon mass spectrometry in analysis of drugs. | Rapid communications in mass spectrometry : RCM 20030101 |
| Mechanisms of impaired biliary excretion of acetaminophen glucuronide after acute phenobarbital treatment or phenobarbital pretreatment. | Drug metabolism and disposition: the biological fate of chemicals 20020901 |
| Effect of enteral vs. parenteral glucose delivery on initial splanchnic glucose uptake in nondiabetic humans. | American journal of physiology. Endocrinology and metabolism 20020801 |
| Effect of nizatidine on paracetamol and its metabolites in human plasma. | The Journal of pharmacy and pharmacology 20020601 |
| Acetaminophen and metabolite: lack of effect on nitric oxide synthase (constitutive or inducible). | Headache 20020301 |
| Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms. | The Journal of pharmacology and experimental therapeutics 20011201 |
| An integrated (2)H and (13)C NMR study of gluconeogenesis and TCA cycle flux in humans. | American journal of physiology. Endocrinology and metabolism 20011001 |
| Methods for measuring glycogen cycling. | American journal of physiology. Endocrinology and metabolism 20010901 |
| Cisapride raises the bioavailability of paracetamol by inhibiting its glucuronidation in man. | The Journal of pharmacy and pharmacology 20010701 |
| Immune thrombocytopenia resulting from sensitivity to metabolites of naproxen and acetaminophen. | Blood 20010615 |
| Type I diabetes mellitus does not alter initial splanchnic glucose extraction or hepatic UDP-glucose flux during enteral glucose administration. | Diabetologia 20010601 |
| High-performance liquid chromatographic assay for acetaminophen glucuronide in human liver microsomes. | Journal of chromatography. B, Biomedical sciences and applications 20010405 |
| Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank. | Pharmacogenetics 20001101 |
| Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. | The Journal of biological chemistry 20000211 |