Home Other Building Blocks ETHYL 4-ISOTHIOCYANATOBUTYRATE

ETHYL 4-ISOTHIOCYANATOBUTYRATE

CAS No.:
17126-65-7
Catalog Number:
AG00ACZG
Molecular Formula:
Molecular Weight:
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
250mg
98%
1 week
United States
$100
- +
1g
98%
1 week
United States
$163
- +
Product Description
Catalog Number:
AG00ACZG
Chemical Name:
ETHYL 4-ISOTHIOCYANATOBUTYRATE
CAS Number:
17126-65-7
MDL Number:
MFCD00041135
IUPAC Name:
ethyl 4-isothiocyanatobutanoate
InChI:
InChI=1S/C7H11NO2S/c1-2-10-7(9)4-3-5-8-6-11/h2-5H2,1H3
InChI Key:
FAGABVVHWPYGBK-UHFFFAOYSA-N
Properties
Complexity:
164  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
173.051g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
173.23g/mol
Monoisotopic Mass:
173.051g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
70.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.1  
Literature
Title Journal
Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells. Molecular cancer 20100101
Administration of isothiocyanate (E-4IB) and cisplatin leads to altered signalling and lysosomal export in human ovarian carcinoma sensitive- and cisplatin-resistant cells. Neoplasma 20090101
Isothiocyanate E-4IB induces MAPK activation, delayed cell cycle transition and apoptosis. Cell proliferation 20070601
Sensitisation for cisplatin-induced apoptosis by isothiocyanate E-4IB leads to signalling pathways alterations. British journal of cancer 20061120
Apoptotic effect of ethyl-4-isothiocyanatobutanoate is associated with DNA damage, proteasomal activity and induction of p53 and p21cip1/waf1. Apoptosis : an international journal on programmed cell death 20060801
Enhanced sensitivity of human ovarian carcinoma cell lines A2780 and A2780/CP to the combination of cisplatin and synthetic isothiocyanate ethyl 4-isothiocyanatobutanoate. Neoplasma 20050101
Immunotoxic and cancerostatic effects of ethyl-4-isothiocyanatobutanoate in female Lewis rats with implanted fibrosarcoma. International immunopharmacology 20021101
Antibacterial and mutagenic activities of new isothiocyanate derivatives. Folia microbiologica 20010101
Properties