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Ilaprazole

CAS No.:
172152-36-2
Catalog Number:
AG00ACA9
Molecular Formula:
C19H18N4O2S
Molecular Weight:
366.4368
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
2mg
98%
1 week
United States
$182
- +
5mg
98%
1 week
United States
$265
- +
10mg
98%
1 week
United States
$390
- +
50mg
98%
1 week
United States
$1237
- +
100mg
98%
1 week
United States
$2001
- +
Product Description
Catalog Number:
AG00ACA9
Chemical Name:
Ilaprazole
CAS Number:
172152-36-2
Molecular Formula:
C19H18N4O2S
Molecular Weight:
366.4368
MDL Number:
MFCD00942538
IUPAC Name:
2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-6-pyrrol-1-yl-1H-benzimidazole
InChI:
InChI=1S/C19H18N4O2S/c1-13-17(20-8-7-18(13)25-2)12-26(24)19-21-15-6-5-14(11-16(15)22-19)23-9-3-4-10-23/h3-11H,12H2,1-2H3,(H,21,22)
InChI Key:
HRRXCXABAPSOCP-UHFFFAOYSA-N
SMILES:
COc1ccnc(c1C)CS(=O)c1nc2c([nH]1)cc(cc2)n1cccc1
Properties
Complexity:
502  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
366.115g/mol
Formal Charge:
0
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
366.439g/mol
Monoisotopic Mass:
366.115g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
92A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
2.3  
Literature
Title Journal
Pharmacokinetic interactions between ilaprazole and clarithromycin following ilaprazole, clarithromycin and amoxicillin triple therapy. Acta pharmacologica Sinica 20120801
Ilaprazole, a new proton pump inhibitor, is primarily metabolized to ilaprazole sulfone by CYP3A4 and 3A5. Xenobiotica; the fate of foreign compounds in biological systems 20120301
Acid inhibition effect of ilaprazole on Helicobacter pylori-negative healthy volunteers: an open randomized cross-over study. Journal of digestive diseases 20120201
Ilaprazole for the treatment of duodenal ulcer: a randomized, double-blind and controlled phase III trial. Current medical research and opinion 20120101
Investigation on the interaction between ilaprazole and bovine serum albumin without or with different C-ring flavonoids from the viewpoint of food-drug interference. Journal of agricultural and food chemistry 20110810
A new PPI, ilaprazole compared with omeprazole in the treatment of duodenal ulcer: a randomized double-blind multicenter trial. Journal of clinical gastroenterology 20110401
Identification of ilaprazole metabolites in human urine by HPLC-ESI-MS/MS and HPLC-NMR experiments. Biomedical chromatography : BMC 20101001
[Evaluation of the effect of ilaprazole on intragastric pH in patients with duodenal ulcer]. Zhonghua nei ke za zhi 20100401
An improved LC-MS/MS method for quantitative determination of ilaprazole and its metabolites in human plasma and its application to a pharmacokinetic study. Acta pharmacologica Sinica 20090901
Randomized, parallel, double-blind comparison of the ulcer-healing effects of ilaprazole and omeprazole in the treatment of gastric and duodenal ulcers. Journal of gastroenterology 20090101
Effects of IY-81149, a newly developed proton pump inhibitor, on gastric acid secretion in vitro and in vivo. Arzneimittel-Forschung 20010101
Comparison of IY81149 with omeprazole in rat reflux oesophagitis. Journal of autonomic pharmacology 20000101
Properties