3-Quinolinecarboxylic acid,7-[(7S)-7-amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-, hydrate (2:3)
| Title | Journal |
|---|---|
| Antimicrobial efficacies of several antibiotics against uterine cervicitis caused by Mycoplasma genitalium. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20120601 |
| Clinical and microbiological outcomes in treatment of men with non-gonococcal urethritis with a 100-mg twice-daily dose regimen of sitafloxacin. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20120601 |
| Effects of systemic sitafloxacin on periodontal infection control in elderly patients. | Gerodontology 20120601 |
| Activity of sitafloxacin against extracellular and intracellular Staphylococcus aureus in vitro and in vivo: comparison with levofloxacin and moxifloxacin. | The Journal of antibiotics 20120501 |
| Sitafloxacin resistance in Helicobacter pylori isolates and sitafloxacin-based triple therapy as a third-line regimen in Japan. | International journal of antimicrobial agents 20120401 |
| Comparative in vitro activity of sitafloxacin against bacteria isolated from Thai patients with urinary tract infections and lower respiratory tract infections. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20120201 |
| Elucidation of the crystal structure-physicochemical property relationship among polymorphs and hydrates of sitafloxacin, a novel fluoroquinolone antibiotic. | International journal of pharmaceutics 20120117 |
| Characterization of non-stoichiometric hydration and the dehydration behavior of sitafloxacin hydrate. | Chemical & pharmaceutical bulletin 20120101 |
| In vitro activity of sitafloxacin against Burkholderia pseudomallei. | International journal of antimicrobial agents 20111001 |
| [Efficacy and safety of sitafloxacin for lower respiratory tract infections]. | The Japanese journal of antibiotics 20111001 |
| [Study on the safety and efficacy of sitafloxacin--results of the use-results survey]. | The Japanese journal of antibiotics 20111001 |
| [Current value of quinolones in Helicobacter pylori therapy]. | Zeitschrift fur Gastroenterologie 20110801 |
| Sitafloxacin: in bacterial infections. | Drugs 20110416 |
| Comparative in vitro and in vivo antimicrobial activities of sitafloxacin, gatifloxacin and moxifloxacin against Mycobacterium avium. | International journal of antimicrobial agents 20110401 |
| Studies on mechanism of thermal crystal transformation of sitafloxacin hydrates through melting and recrystallization, yielding different anhydrates depending on initial crystalline forms. | International journal of pharmaceutics 20101215 |
| [In vitro activity of sitafloxacin against clinical isolates in 2009]. | The Japanese journal of antibiotics 20101201 |
| [Susceptibility test of the Mycobacterium avium complex to sixteen anti-infective agents]. | Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20100501 |
| In vivo efficacy of sitafloxacin in a new murine model of non-typeable Haemophilus influenzae pneumonia by sterile intratracheal tube. | International journal of antimicrobial agents 20090901 |
| Convulsant activity of sitafloxacin and its interactions with anti-inflammatory drugs in mice. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20090801 |
| [Clinical position of sitafloxacin in outpatient chemotherapy. (discussion)]. | The Japanese journal of antibiotics 20090601 |
| Comparative mutant prevention concentration and mutant selection window of sitafloxacin versus other quinolones using strains of Haemophilus influenzae with decreasing susceptibility to levofloxacin. | International journal of antimicrobial agents 20090501 |
| [Pharmacological profile and clinical efficacy of sitafloxacin, a novel quinolone antibacterial agent]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20090101 |
| Quinolones with enhanced bactericidal activity induce autolysis in Streptococcus pneumoniae. | Chemotherapy 20090101 |
| Dual-targeting properties of the 3-aminopyrrolidyl quinolones, DC-159a and sitafloxacin, against DNA gyrase and topoisomerase IV: contribution to reducing in vitro emergence of quinolone-resistant Streptococcus pneumoniae. | The Journal of antimicrobial chemotherapy 20080701 |
| Sitafloxacin hydrate for bacterial infections. | Drugs of today (Barcelona, Spain : 1998) 20080701 |
| The potent antibacterial activity of Sitafloxacin against fluoroquinolone-resistant clinical isolates of Vibrio cholerae O1. | Microbiology and immunology 20070101 |
| In vitro activity of sitafloxacin against clinical strains of Streptococcus pneumoniae with defined amino acid substitutions in QRDRs of gyrase A and topoisomerase IV. | The Journal of antimicrobial chemotherapy 20061201 |
| [Separation of sitafloxacin epimers by capillary electrophoresis]. | Se pu = Chinese journal of chromatography 20060901 |
| In vitro activity of sitafloxacin compared with several fluoroquinolones against Streptococcus anginosus and Streptococcus constellatus. | International journal of antimicrobial agents 20060201 |
| Quantitative assessment of the hepatic pharmacokinetics of the antimicrobial sitafloxacin in humans using in vivoF magnetic resonance spectroscopy. | British journal of clinical pharmacology 20050201 |
| In vitro activities of 11 fluoroquinolones against 816 non-typhoidal strains of Salmonella enterica isolated from Finnish patients with special reference to reduced ciprofloxacin susceptibility. | Annals of clinical microbiology and antimicrobials 20050101 |
| In vivo experimental approach for the risk assessment of fluoroquinolone antibacterial agents-induced long QT syndrome. | European journal of pharmacology 20040220 |
| Pharmacokinetics, tissue distribution, and excretion of sitafloxacin, a new fluoroquinolone antibiotic, in rats, dogs, and monkeys. | Arzneimittel-Forschung 20040101 |
| MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 2: achieving activity in vivo through the use of alternative scaffolds. | Bioorganic & medicinal chemistry letters 20031201 |
| A randomized controlled trial (volunteer study) of sitafloxacin, enoxacin, levofloxacin and sparfloxacin phototoxicity. | The British journal of dermatology 20031201 |
| Comparative antimicrobial activities of gatifloxacin, sitafloxacin and levofloxacin against Mycobacterium tuberculosis replicating within Mono Mac 6 human macrophage and A-549 type II alveolar cell lines. | The Journal of antimicrobial chemotherapy 20030801 |
| In vivo susceptibility of Mycobacterium leprae to sitafloxacin (DU-6859a), either singly or in combination with rifampicin analogues. | International journal of antimicrobial agents 20030301 |
| In-vitro activity of sitafloxacin (DU-6859a), either singly or in combination with rifampin analogs, against Mycobacterium leprae. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20030301 |
| Activities of sitafloxacin (DU-6859a), either singly or in combination with rifampin, against Mycobacterium ulcerans infection in mice. | Journal of chemotherapy (Florence, Italy) 20030201 |
| Sitafloxacin: DU 6859, DU 6859A, Gracevit, sitafloxacin hydrate. | Drugs in R&D 20030101 |
| In vitro activity of sitafloxacin (DU-6859a) alone, or in combination with rifampicin, against Mycobacterium ulcerans. | The Journal of antimicrobial chemotherapy 20021101 |
| Anti-Mycobacterium tuberculosis activities of new fluoroquinolones in combination with other antituberculous drugs. | The Journal of infection 20020401 |
| Photochemical behavior of sitafloxacin, fluoroquinolone antibiotic, in an aqueous solution. | Chemical & pharmaceutical bulletin 20020201 |
| Antimicrobial activities of clarithromycin, gatifloxacin and sitafloxacin, in combination with various antimycobacterial drugs against extracellular and intramacrophage Mycobacterium avium complex. | International journal of antimicrobial agents 20020201 |
| Pharmacokinetics and absolute bioavailability of sitafloxacin, a new fluoroquinolone antibiotic, in healthy male and female Caucasian subjects. | Xenobiotica; the fate of foreign compounds in biological systems 20011101 |
| Phototoxic retinal degeneration and toxicokinetics of sitafloxacin, a quinolone antibacterial agent, in mice. | Archives of toxicology 20010901 |
| In vitro activity of sitafloxacin against Clostridium difficile. | The Journal of antimicrobial chemotherapy 20010501 |
| An open, randomised, multi-centre study comparing the safety and efficacy of sitafloxacin and imipenem/cilastatin in the intravenous treatment of hospitalised patients with pneumonia. | International journal of antimicrobial agents 20010301 |
| Recent advances in the field of quinolones. | Farmaco (Societa chimica italiana : 1989) 20010101 |
| Possible relationship between phototoxicity and photodegradation of sitafloxacin, a quinolone antibacterial agent, in the auricular skin of albino mice. | Toxicological sciences : an official journal of the Society of Toxicology 20000801 |
| Comparative in vitro antimicrobial activities of the newly synthesized quinolone HSR-903, sitafloxacin (DU-6859a), gatifloxacin (AM-1155), and levofloxacin against Mycobacterium tuberculosis and Mycobacterium avium complex. | Antimicrobial agents and chemotherapy 19991201 |
| Dual inhibitory activity of sitafloxacin (DU-6859a) against DNA gyrase and topoisomerase IV of Streptococcus pneumoniae. | The Journal of antimicrobial chemotherapy 19991001 |
| In vitro and in vivo antifungal activities of DU-6859a, a fluoroquinolone, in combination with amphotericin B and fluconazole against pathogenic fungi. | Antimicrobial agents and chemotherapy 19950701 |
| Pharmacokinetics and tolerance of DU-6859a, a new fluoroquinolone, after single and multiple oral doses in healthy volunteers. | Antimicrobial agents and chemotherapy 19950101 |
| In vitro and in vivo antimycobacterial activities of a new quinolone, DU-6859a. | Antimicrobial agents and chemotherapy 19941201 |