Ranirestat
Title | Journal |
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A concise enantioselective synthesis of (-)-ranirestat. | Organic letters 20100319 |
Aldose reductase inhibitors in the treatment of diabetic peripheral neuropathy: a review. | Journal of diabetes and its complications 20100101 |
Inventing and understanding catalytic, enantioselective reactions. | Current opinion in drug discovery & development 20091101 |
Ranirestat for the management of diabetic sensorimotor polyneuropathy. | Diabetes care 20090701 |
Improvement of motor nerve conduction velocity in diabetic rats requires normalization of the polyol pathway metabolites flux. | Journal of pharmacological sciences 20090201 |
An improved lanthanum catalyst system for asymmetric amination: toward a practical asymmetric synthesis of AS-3201 (Ranirestat). | Organic letters 20080703 |
Long-term treatment with ranirestat (AS-3201), a potent aldose reductase inhibitor, suppresses diabetic neuropathy and cataract formation in rats. | Journal of pharmacological sciences 20080701 |
Ranirestat (AS-3201), a potent aldose reductase inhibitor, reduces sorbitol levels and improves motor nerve conduction velocity in streptozotocin-diabetic rats. | Journal of pharmacological sciences 20080701 |
Stability and hydrolysis kinetics of spirosuccinimide type inhibitors of aldose reductase in aqueous solution and retardation of their hydrolysis by the target enzyme. | Journal of pharmaceutical sciences 20080401 |
Ranirestat as a therapeutic aldose reductase inhibitor for diabetic complications. | Expert opinion on investigational drugs 20080401 |
Stereospecific recognition of a spirosuccinimide type aldose reductase inhibitor (AS-3201) by plasma proteins: a significant role of specific binding by serum albumin in the improved potency and stability. | Biochemical pharmacology 20060112 |
Long-term effects of ranirestat (AS-3201) on peripheral nerve function in patients with diabetic sensorimotor polyneuropathy. | Diabetes care 20060101 |
[Role of polyol pathway in pathogenesis of diabetic microangiopathy]. | Nihon rinsho. Japanese journal of clinical medicine 20050601 |
[Progress on the drug therapy for diabetic microangiopathies: aldose reductase inhibitor]. | Nihon rinsho. Japanese journal of clinical medicine 20050601 |
Aldose reductase inhibition by AS-3201 in sural nerve from patients with diabetic sensorimotor polyneuropathy. | Diabetes care 20041001 |
Uridine diphosphate sugar-selective conjugation of an aldose reductase inhibitor (AS-3201) by UDP-glucuronosyltransferase 2B subfamily in human liver microsomes. | Biochemical pharmacology 20040401 |
Stereospecific interaction of a novel spirosuccinimide type aldose reductase inhibitor, AS-3201, with aldose reductase. | Biochemistry 20010727 |