Imidafenacin
| Title | Journal |
|---|---|
| Characterization of muscarinic receptor binding by the novel radioligand, [(3)H]imidafenacin, in the bladder and other tissues of rats. | Journal of pharmacological sciences 20160701 |
| Pharmacokinetics and toxicity of antimuscarinic drugs for overactive bladder treatment in females. | Expert opinion on drug metabolism & toxicology 20121101 |
| Characterization of bladder selectivity of antimuscarinic agents on the basis of in vivo drug-receptor binding. | International neurourology journal 20120901 |
| Excitatory effect of propiverine hydrochloride on urethral activity in rats. | International journal of urology : official journal of the Japanese Urological Association 20120601 |
| Neurogenic bladder. | Advances in urology 20120101 |
| Effect of imidafenacin on nocturia and sleep disorder in patients with overactive bladder. | Urologia internationalis 20120101 |
| [Investigation of pharmacokinetics of crushed imidafenacin 0.1-mg tablet after single oral administration in healthy men]. | Hinyokika kiyo. Acta urologica Japonica 20111201 |
| Effect of oxybutynin and imidafenacin on central muscarinic receptor occupancy and cognitive function: a monkey PET study with [(11)C](+)3-MPB. | NeuroImage 20110901 |
| In vivo bladder selectivity of imidafenacin, a novel antimuscarinic agent, assessed by using an effectiveness index for bladder capacity in rats. | Naunyn-Schmiedeberg's archives of pharmacology 20110901 |
| Quantitative analysis of pseudopolymorphic transformation of imidafenacin by application of a novel combination of near-infrared spectroscopy and a humidity-controlled 96-well plate. | The Journal of pharmacy and pharmacology 20110701 |
| Antimuscarinics suppress adenosine triphosphate and prostaglandin E2 release from urothelium with potential improvement in detrusor overactivity in rats with cerebral infarction. | The Journal of urology 20110601 |
| Selective binding of bladder muscarinic receptors in relation to the pharmacokinetics of a novel antimuscarinic agent, imidafenacin, to treat overactive bladder. | The Journal of pharmacology and experimental therapeutics 20110201 |
| [Efficacy and safety of imidafenacin in female patients with urge and mixed urinary incontinence]. | Hinyokika kiyo. Acta urologica Japonica 20110101 |
| Immediate effect on overactive bladder symptoms following administration of imidafenacin. | Urologia internationalis 20110101 |
| An overview of the clinical use of antimuscarinics in the treatment of overactive bladder. | Advances in urology 20110101 |
| The efficacy and safety of propiverine hydrochloride in patients with overactive bladder symptoms who poorly responded to previous anticholinergic agents. | Advances in urology 20110101 |
| Comparative Evaluation of the Safety and Efficacy of Long-Term Use of Imidafenacin and Solifenacin in Patients with Overactive Bladder: A Prospective, Open, Randomized, Parallel-Group Trial (the LIST Study). | Advances in urology 20110101 |
| Application of a novel combination of near-infrared spectroscopy and a humidity-controlled 96-well plate to the characterization of the polymorphism of imidafenacin. | The Journal of pharmacy and pharmacology 20101101 |
| Noninvasive evaluation of brain muscarinic receptor occupancy of oxybutynin, darifenacin and imidafenacin in rats by positron emission tomography. | Life sciences 20100731 |
| The add-on effect of solifenacin for patients with remaining overactive bladder after treatment with tamsulosin for lower urinary tract symptoms suggestive of benign prostatic obstruction. | Advances in urology 20100101 |
| A randomized, double-blind, placebo- and propiverine-controlled trial of the novel antimuscarinic agent imidafenacin in Japanese patients with overactive bladder. | International journal of urology : official journal of the Japanese Urological Association 20090501 |
| Comparison of the effect of anti-muscarinic agents on bladder activity, urinary ATP level, and autonomic nervous system in rats. | Biomedical research (Tokyo, Japan) 20090401 |
| Suspected differential interactions of digoxin with imidafenacin and propantheline; some thoughts for introspection. | Drug metabolism and pharmacokinetics 20090101 |
| Response to 'Suspected differential interactions of digoxin with imidafenacin and propantheline; some thoughts for introspection'. | Drug metabolism and pharmacokinetics 20090101 |
| Long-term safety, tolerability, and efficacy of the novel anti-muscarinic agent imidafenacin in Japanese patients with overactive bladder. | International journal of urology : official journal of the Japanese Urological Association 20081001 |
| A randomized, double-blind, placebo-controlled phase II dose-finding study of the novel anti-muscarinic agent imidafenacin in Japanese patients with overactive bladder. | International journal of urology : official journal of the Japanese Urological Association 20080901 |
| Validation and application of a 96-well format solid-phase extraction and liquid chromatography-tandem mass spectrometry method for the quantitation of digoxin in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080615 |
| [Pharmacological and clinical profile of imidafenacin developed as a new therapeutic agent for overactive bladder]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20080501 |
| Effect of itraconazole on the pharmacokinetics of imidafenacin in healthy subjects. | Journal of clinical pharmacology 20080301 |
| Absolute bioavailability of imidafenacin after oral administration to healthy subjects. | British journal of clinical pharmacology 20080201 |
| No effect of imidafenacin, a novel antimuscarinic drug, on digoxin pharmacokinetics in healthy subjects. | Drug metabolism and pharmacokinetics 20080101 |
| Population pharmacokinetic analysis of a novel muscarinic receptor antagonist, imidafenacin, in healthy volunteers and overactive bladder patients. | Drug metabolism and pharmacokinetics 20080101 |
| Development and validation of bioanalytical methods for imidafenacin (KRP-197/ONO-8025) and its metabolites in human urine by using liquid chromatography-tandem mass spectrometry. | Biomedical chromatography : BMC 20070901 |
| Absorption, metabolism, and excretion of [14C]imidafenacin, a new compound for treatment of overactive bladder, after oral administration to healthy male subjects. | Drug metabolism and disposition: the biological fate of chemicals 20070901 |
| Synthesis of the metabolites of 4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide (KRP-197/ONO-8025). | Chemical & pharmaceutical bulletin 20070701 |
| Development and validation of bioanalytical methods for Imidafenacin (KRP-197/ONO-8025) and its metabolites in human plasma by liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070615 |
| Drug-drug interactions in the metabolism of imidafenacin: role of the human cytochrome P450 enzymes and UDP-glucuronic acid transferases, and potential of imidafenacin to inhibit human cytochrome P450 enzymes. | Xenobiotica; the fate of foreign compounds in biological systems 20070201 |
| Effects of imidafenacin (KRP-197/ONO-8025), a new anti-cholinergic agent, on muscarinic acetylcholine receptors. High affinities for M3 and M1 receptor subtypes and selectivity for urinary bladder over salivary gland. | Arzneimittel-Forschung 20070101 |
| Pharmacological effects of imidafenacin (KRP-197/ONO-8025), a new bladder selective anti-cholinergic agent, in rats. Comparison of effects on urinary bladder capacity and contraction, salivary secretion and performance in the Morris water maze task. | Arzneimittel-Forschung 20070101 |
| Pharmacological effects of KRP-197 on the human isolated urinary bladder. | Urologia internationalis 20030101 |
| Biomimetic oxidation of 2-methylimidazole derivative with a chemical model system for cytochrome P-450. | Chemical & pharmaceutical bulletin 20020801 |
| Muscarinic receptors of the urinary bladder: detrusor, urothelial and prejunctional. | Autonomic & autacoid pharmacology 20020601 |
| Synthesis and antimuscarinic activity of a series of 4-(1-Imidazolyl)-2,2-diphenylbutyramides: discovery of potent and subtype-selective antimuscarinic agents. | Bioorganic & medicinal chemistry 19990601 |