Name: Name:CTS-1027
Brand: Angene
SKU: AG00ABJK
Rating: 90 (10 reviews)

CTS-1027

CAS No.:

193022-04-7

Catalog Number:

AG00ABJK

Molecular Formula:

C19H20ClNO6S

Molecular Weight:

425.8832

Pack Size

Purity

Availability

Location

Price(USD)

Quantity

5mg

98%

1 week

United States

$350

- +

10mg

98%

1 week

United States

$607

- +

50mg

98%

1 week

United States

$1671

- +

Product Description

Catalog Number:

AG00ABJK

Chemical Name:

CTS-1027

CAS Number:

193022-04-7

Molecular Formula:

C19H20ClNO6S

Molecular Weight:

425.8832

MDL Number:

MFCD16657131

IUPAC Name:

4-[[4-(4-chlorophenoxy)phenyl]sulfonylmethyl]-N-hydroxyoxane-4-carboxamide

InChI:

InChI=1S/C19H20ClNO6S/c20-14-1-3-15(4-2-14)27-16-5-7-17(8-6-16)28(24,25)13-19(18(22)21-23)9-11-26-12-10-19/h1-8,23H,9-13H2,(H,21,22)

InChI Key:

ROSNVSQTEGHUKU-UHFFFAOYSA-N

SMILES:

ONC(=O)C1(CCOCC1)CS(=O)(=O)c1ccc(cc1)Oc1ccc(cc1)Cl

UNII:

2QD3F58224

Properties

Complexity:

615

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Exact Mass:

425.07g/mol

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Molecular Weight:

425.88g/mol

Monoisotopic Mass:

425.07g/mol

Rotatable Bond Count:

Topological Polar Surface Area:

110A^2

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

XLogP3:

2.3

Literature

Title	Journal
Orally active MMP-1 sparing α-tetrahydropyranyl and α-piperidinyl sulfone matrix metalloproteinase (MMP) inhibitors with efficacy in cancer, arthritis, and cardiovascular disease.	Journal of medicinal chemistry 20100923
Hydroxamates: relationships between structure and plasma stability.	Journal of medicinal chemistry 20091112
Discovery of potent, selective, and orally active carboxylic acid based inhibitors of matrix metalloproteinase-13.	Journal of medicinal chemistry 20090611
Synthesis and structure-activity relationship of N-substituted 4-arylsulfonylpiperidine-4-hydroxamic acids as novel, orally active matrix metalloproteinase inhibitors for the treatment of osteoarthritis.	Journal of medicinal chemistry 20030605
Protease inhibitors: current status and future prospects.	Journal of medicinal chemistry 20000210

Properties