AP20187
Title | Journal |
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Controlled dimerization of insulin-like growth factor-1 and insulin receptors reveals shared and distinct activities of holo and hybrid receptors. | The Journal of biological chemistry 20180309 |
Targeting colorectal cancer stem cells with inducible caspase-9. | Apoptosis : an international journal on programmed cell death 20120501 |
[The Yin and the Yang of senescence: is it possible to age without developing cancer?]. | Medecine sciences : M/S 20120301 |
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. | Nature 20111102 |
Long-term regulation of genetically modified primary hematopoietic cells in dogs. | Molecular therapy : the journal of the American Society of Gene Therapy 20110701 |
Generating mouse models of degenerative diseases using Cre/lox-mediated in vivo mosaic cell ablation. | The Journal of clinical investigation 20110601 |
Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells. | Cancer research 20101201 |
Distinct macrophage subpopulations regulate viral encephalitis but not viral clearance in the CNS. | Journal of neuroimmunology 20100914 |
Death switch for gene therapy: application to erythropoietin transgene expression. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20100701 |
eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memory consolidation without affecting general translation. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100217 |
Suppression of the intrinsic apoptosis pathway by synaptic activity. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100217 |
Aggregation and amyloid fibril formation induced by chemical dimerization of recombinant prion protein in physiological-like conditions. | The Journal of biological chemistry 20091106 |
A novel inducible tyrosine kinase receptor to regulate signal transduction and neurite outgrowth. | Journal of neuroscience research 20090901 |
Chemically inducible inactivation of protein synthesis in genetically targeted neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090527 |
Controlled rod cell ablation in transgenic Xenopus laevis. | Investigative ophthalmology & visual science 20090201 |
Cancer gene therapy with iCaspase-9 transcriptionally targeted to tumor endothelial cells. | Cancer gene therapy 20081001 |
PANIC-ATTAC: a mouse model for inducible and reversible beta-cell ablation. | Diabetes 20080801 |
Expansion of multipotent and lymphoid-committed human progenitors through intracellular dimerization of Mpl. | Blood 20080415 |
Comparison of the lateral tail vein and the retro-orbital venous sinus as routes of intravenous drug delivery in a transgenic mouse model. | Lab animal 20080101 |
Constitutive and AP20187-induced Ret activation in photoreceptors does not protect from light-induced damage. | Investigative ophthalmology & visual science 20071101 |
Selective control of endothelial cell proliferation with a synthetic dimerizer of FGF receptor-1. | Laboratory investigation; a journal of technical methods and pathology 20070801 |
Aggregation of cellular prion protein is initiated by proximity-induced dimerization. | Journal of neurochemistry 20070801 |
AP20187-mediated activation of a chimeric insulin receptor results in insulin-like actions in skeletal muscle and liver of diabetic mice. | Human gene therapy 20070201 |
The survival of differentiating embryonic stem cells is dependent on the SCF-KIT pathway. | Journal of cell science 20060801 |
Development of peritoneal adhesions in macrophage depleted mice. | The Journal of surgical research 20060401 |
Establishment of a cell model based on FKBP12 dimerization for screening of FK506-like neurotrophic small molecular compounds. | Journal of biomolecular screening 20060401 |
Establishment of cell lines that exhibit correct ontogenic stage-specific gene expression profiles from tissues of yeast artificial chromosome transgenic mice using chemically induced growth signals. | Methods in molecular biology (Clifton, N.J.) 20060101 |
Regulated dimerization of the thyrotropin-releasing hormone receptor affects receptor trafficking but not signaling. | Molecular endocrinology (Baltimore, Md.) 20051101 |
Specific pharmacological dimerization of KDR in lentivirally transduced human hematopoietic cells activates anti-apoptotic and proliferative mechanisms. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051001 |
Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy. | Nature medicine 20050701 |
Dimer formation of receptor activator of nuclear factor kappaB induces incomplete osteoclast formation. | Biochemical and biophysical research communications 20041203 |
Pharmacological regulation of the insulin receptor signaling pathway mimics insulin action in cells transduced with viral vectors. | Human gene therapy 20041101 |
Differences in F36VMpl-based in vivo selection among large animal models. | Molecular therapy : the journal of the American Society of Gene Therapy 20041001 |
In vivo selection of genetically modified erythroid cells using a jak2-based cell growth switch. | Molecular therapy : the journal of the American Society of Gene Therapy 20040901 |
[Promotion of in vitro long term expansion of primitive multipotential hematopoietic cells by transduced JAK2 gene]. | Zhonghua yi xue za zhi 20040602 |
Conditional macrophage ablation in transgenic mice expressing a Fas-based suicide gene. | Journal of leukocyte biology 20040401 |
[Long term regulated expansion and committed differentiation of JAK2 gene transfected hematopoietic stem/progenitor cells in vitro]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20040201 |
Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2. | The EMBO journal 20040114 |
Glycoprotein Ib-IX-mediated activation of integrin alpha(IIb)beta(3): effects of receptor clustering and von Willebrand factor adhesion. | Journal of thrombosis and haemostasis : JTH 20030601 |
Daxx enhances Fas-mediated apoptosis in a murine pro-B cell line, BAF3. | FEBS letters 20030410 |
An inducible system for the study of FGF signalling in early amphibian development. | Developmental biology 20030401 |
Activation of procaspases by FK506 binding protein-mediated oligomerization. | Science's STKE : signal transduction knowledge environment 20030128 |
Small-molecule-directed mpl signaling can complement growth factors to selectively expand genetically modified cord blood cells. | Stem cells (Dayton, Ohio) 20030101 |
Conditional cell ablation by tight control of caspase-3 dimerization in transgenic mice. | Nature biotechnology 20021201 |
Pharmacologically regulated in vivo selection in a large animal. | Blood 20020915 |
Ablation of microvessels in vivo upon dimerization of iCaspase-9. | Gene therapy 20020401 |
Dimerizer-induced proliferation of genetically modified hepatocytes. | Molecular therapy : the journal of the American Society of Gene Therapy 20020401 |