TAPI-1
| Title | Journal |
|---|---|
| Preventing cleavage of Mer promotes efferocytosis and suppresses acute lung injury in bleomycin treated mice. | Toxicology and applied pharmacology 20120815 |
| Sjögren's syndrome autoantibodies provoke changes in gene expression profiles of inflammatory cytokines triggering a pathway involving TACE/NF-κB. | Laboratory investigation; a journal of technical methods and pathology 20120401 |
| Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in the adult mouse utricles. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20111026 |
| Two functionally distinct isoforms of TL1A (TNFSF15) generated by differential ectodomain shedding. | The journals of gerontology. Series A, Biological sciences and medical sciences 20101101 |
| Human ROBO1 is cleaved by metalloproteinases and gamma-secretase and migrates to the nucleus in cancer cells. | FEBS letters 20100702 |
| Sorafenib inhibits the shedding of major histocompatibility complex class I-related chain A on hepatocellular carcinoma cells by down-regulating a disintegrin and metalloproteinase 9. | Hepatology (Baltimore, Md.) 20100401 |
| Tumor necrosis factor-alpha processing inhibitor-1 inhibits skin fibrosis in a bleomycin-induced murine model of scleroderma. | Experimental dermatology 20100101 |
| Release of soluble tumor necrosis factor receptor 1 from corneal epithelium by TNF-alpha-converting enzyme-dependent ectodomain shedding. | Investigative ophthalmology & visual science 20091001 |
| Cell migration in response to the amino-terminal fragment of urokinase requires epidermal growth factor receptor activation through an ADAM-mediated mechanism. | Journal of vascular surgery 20090501 |
| Aldose reductase regulates high glucose-induced ectodomain shedding of tumor necrosis factor (TNF)-alpha via protein kinase C-delta and TNF-alpha converting enzyme in vascular smooth muscle cells. | Endocrinology 20090101 |
| Activated human neutrophils rapidly release the chemotactically active D2D3 form of the urokinase-type plasminogen activator receptor (uPAR/CD87). | Molecular and cellular biochemistry 20090101 |
| Novel approach for formation of platelet-like particles from mouse embryonic stem cells without using feeder cells. | The Kurume medical journal 20090101 |
| Neuronal RA175/SynCAM1 isoforms are processed by tumor necrosis factor-alpha-converting enzyme (TACE)/ADAM17-like proteases. | Neuroscience letters 20081017 |
| Gamma-secretase and metalloproteinase activity regulate the distribution of endoplasmic reticulum to hippocampal neuron dendritic spines. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080801 |
| Endogenous secreted amyloid precursor protein-alpha regulates hippocampal NMDA receptor function, long-term potentiation and spatial memory. | Neurobiology of disease 20080801 |
| Luteinizing hormone signaling in preovulatory follicles involves early activation of the epidermal growth factor receptor pathway. | Molecular endocrinology (Baltimore, Md.) 20080401 |
| Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea. | Developmental biology 20080401 |
| Heparin-binding epidermal growth factor and Src family kinases in proliferation of renal epithelial cells. | American journal of physiology. Renal physiology 20080301 |
| Ectodomain shedding of neuroglycan C, a brain-specific chondroitin sulfate proteoglycan, by TIMP-2- and TIMP-3-sensitive proteolysis. | Journal of neurochemistry 20070901 |
| Hydrogen peroxide and endothelin-1 are novel activators of betacellulin ectodomain shedding. | Journal of cellular biochemistry 20061001 |
| Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen Chlamydia trachomatis by targeting peptide deformylase of the bacterium. | The Journal of biological chemistry 20060616 |
| Metalloprotease-dependent amphiregulin release mediates tumor necrosis factor-alpha-induced IL-8 secretion in the human airway epithelial cell line NCI-H292. | Life sciences 20060522 |
| APPepsilon, the epsilon-secretase-derived N-terminal product of the beta-amyloid precursor protein, behaves as a type I protein and undergoes alpha-, beta-, and gamma-secretase cleavages. | Journal of neurochemistry 20060501 |
| Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates GPIbalpha shedding from platelets in vitro and in vivo. | Circulation research 20041001 |
| Tumor necrosis factor alpha stimulates MUC1 synthesis and ectodomain release in a human uterine epithelial cell line. | Endocrinology 20040901 |
| Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization. | Journal of molecular neuroscience : MN 20040101 |
| Tomoregulin ectodomain shedding by proinflammatory cytokines. | Life sciences 20030815 |
| Tumor necrosis factor-alpha converting enzyme/ADAM 17 mediates MUC1 shedding. | The Journal of biological chemistry 20030131 |
| Chemotactic agents induce IL-6Ralpha shedding from polymorphonuclear cells: involvement of a metalloproteinase of the TNF-alpha-converting enzyme (TACE) type. | European journal of immunology 20021001 |
| Endotoxin induces rapid metalloproteinase-mediated shedding followed by up-regulation of the monocyte hemoglobin scavenger receptor CD163. | Journal of leukocyte biology 20021001 |
| Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-alpha converting enzyme. | The Biochemical journal 20010801 |
| A permissive role for tumor necrosis factor in vascular endothelial growth factor-induced vascular permeability. | Blood 20010301 |
| Cleavage and shedding of E-cadherin after induction of apoptosis. | The Journal of biological chemistry 20010216 |
| Reactive oxygen species mediate tumor necrosis factor alpha-converting, enzyme-dependent ectodomain shedding induced by phorbol myristate acetate. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010201 |