Home Other Building Blocks Myo-Inositol 1,2,3-Trisphosphate

Myo-Inositol 1,2,3-Trisphosphate

CAS No.:
1311140-98-3
Catalog Number:
AG009XS0
Molecular Formula:
Molecular Weight:
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Product Description
Catalog Number:
AG009XS0
Chemical Name:
Myo-Inositol 1,2,3-Trisphosphate
CAS Number:
1311140-98-3
IUPAC Name:
[(1S,2S,4R,5S)-2,3,4-trihydroxy-5,6-diphosphonooxycyclohexyl] dihydrogen phosphate
InChI:
InChI=1S/C6H15O15P3/c7-1-2(8)4(19-22(10,11)12)6(21-24(16,17)18)5(3(1)9)20-23(13,14)15/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)/t1?,2-,3+,4-,5-,6?/m0/s1
InChI Key:
GKDKOMAJZATYAY-LXOASSSBSA-N
Properties
Complexity:
536  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
419.962g/mol
Formal Charge:
0
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
15  
Hydrogen Bond Donor Count:
9  
Isotope Atom Count:
0
Molecular Weight:
420.092g/mol
Monoisotopic Mass:
419.962g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
261A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-7  
Literature
Title Journal
Potentiometric and ³¹P NMR studies on inositol phosphates and their interaction with iron(III) ions. Carbohydrate research 20110301
Modeling natural anti-inflammatory compounds by molecular topology. International journal of molecular sciences 20110101
Conformational analysis of the natural iron chelator myo-inositol 1,2,3-trisphosphate using a pyrene-based fluorescent mimic. Organic & biomolecular chemistry 20100621
The behaviour of inositol 1,3,4,5,6-pentakisphosphate in the presence of the major biological metal cations. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20090901
'Chelatable iron pool': inositol 1,2,3-trisphosphate fulfils the conditions required to be a safe cellular iron ligand. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20090101
Negative regulation of parathyroid hormone (PTH)-activated phospholipase C by PTH/PTH-related peptide receptor phosphorylation and protein kinase A. Endocrinology 20080801
Modelling biological modularity with CellML. IET systems biology 20080301
Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington disease. The Journal of biological chemistry 20080227
IGF-I enhances cortisol secretion from guinea-pig adrenal gland: in vivo and in vitro study. International journal of molecular medicine 20070701
Unitary permeability of gap junction channels to second messengers measured by FRET microscopy. Nature methods 20070401
alpha-Trinositol inhibits FGF-stimulated growth of smooth muscle and breast cancer cells. Biochemical and biophysical research communications 20041217
Spatiotemporal patterning of IP3-mediated Ca2+ signals in Xenopus oocytes by Ca2+-binding proteins. The Journal of physiology 20040415
Regulation of dendritic cell trafficking by the ADP-ribosyl cyclase CD38: impact on the development of humoral immunity. Immunity 20040301
Evidence that IP3 and ryanodine-sensitive intra-cellular Ca2+ stores are not involved in acute hyposmotically-induced prolactin release in Tilapia. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20040101
Lyso-glycosphingolipids mobilize calcium from brain microsomes via multiple mechanisms. The Biochemical journal 20031101
A possible role of HSP70 in mediating cardioprotection in patients undergoing CABG. Molecular and cellular biochemistry 20030501
Cyclosporin effect on rat aorta alpha(1)-adrenoceptors and their transduction mechanisms. Journal of cardiovascular pharmacology 20020801
Properties