Sardomozide 2HCl
| Title | Journal |
|---|---|
| Down-regulation of hypusine biosynthesis in Plasmodium by inhibition of S-adenosyl-methionine-decarboxylase. | Amino acids 20100201 |
| Polyamine depletion with two different polyamine analogues causes DNA damage in human breast cancer cell lines. | DNA and cell biology 20080901 |
| Effect of the polyamine analogue N1,N11-diethylnorspermine on cell survival and susceptibility to apoptosis of human chondrocytes. | Journal of cellular physiology 20080701 |
| Polyamine biosynthesis as a target to inhibit apoptosis of non-tumoral cells. | Amino acids 20070801 |
| Suppression of TNF-alpha production by S-adenosylmethionine in human mononuclear leukocytes is not mediated by polyamines. | Biological chemistry 20061201 |
| Inhibition of multidrug-resistant HIV-1 by interference with cellular S-adenosylmethionine decarboxylase activity. | The Journal of infectious diseases 20060915 |
| Mechanisms of allosteric regulation of Trypanosoma cruzi S-adenosylmethionine decarboxylase. | Biochemistry 20060627 |
| Multi-centre Phase II trial of the polyamine synthesis inhibitor SAM486A (CGP48664) in patients with metastatic melanoma. | Investigational new drugs 20050601 |
| Effects of polyamine synthesis inhibitors on primary tumor features and metastatic capacity of human breast cancer cells. | Clinical & experimental metastasis 20050101 |
| Inhibitors of polyamine biosynthesis decrease the expression of the metalloproteases meprin alpha and MMP-7 in hormone-independent human breast cancer cells. | Clinical & experimental metastasis 20050101 |
| Biological activity of the S-adenosylmethionine decarboxylase inhibitor SAM486A in human breast cancer cells in vitro and in vivo. | International journal of oncology 20041201 |
| The role of polyamines in human cancer: prospects for drug combination therapies. | Hawaii medical journal 20041201 |
| Phase I and pharmacokinetic study of the polyamine synthesis inhibitor SAM486A in combination with 5-fluorouracil/leucovorin in metastatic colorectal cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040315 |
| Clinical efficacy, tolerability, and safety of SAM486A, a novel polyamine biosynthesis inhibitor, in patients with relapsed or refractory non-Hodgkin's lymphoma: results from a phase II multicenter study. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040215 |
| A phase I and pharmacokinetic study of SAM486A, a novel polyamine biosynthesis inhibitor, administered on a daily-times-five every-three-week schedule in patients with Advanced solid malignancies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020701 |
| Detection and separation of the S-adenosylmethionine-decarboxylase inhibitor SAM486A in human plasma and urine by reversed-phase ion-pairing high-performance liquid chromatography. | Journal of pharmacological and toxicological methods 20010101 |
| 4-Amidinoindan-1-one 2'-amidinohydrazone: a new potent and selective inhibitor of S-Adenosylmethionine decarboxylase. | Journal of medicinal chemistry 19930723 |