Lerisetron
Title | Journal |
---|---|
Pharmacokinetic-pharmacodynamic modeling of the hydroxy lerisetron metabolite L6-OH in rats: an integrated parent-metabolite model. | Pharmaceutical research 20051101 |
Subunit rotation models activation of serotonin 5-HT3AB receptors by agonists. | Journal of computer-aided molecular design 20041001 |
Lerisetron. FAES. | Current opinion in investigational drugs (London, England : 2000) 20030701 |
Age-related changes in pharmacokinetics and pharmacodynamics of lerisetron in the rat: a population pharmacokinetic model. | Gerontology 20030101 |
Synthesis and pharmacology of isoquinuclidine derivatives as 5-HT(3) ligands. | Bioorganic & medicinal chemistry letters 20020121 |
Pharmacokinetics and pharmacological effect of lerisetron, a new 5-HT3 antagonist, in rats. | Journal of pharmaceutical sciences 20020101 |
Functional group interactions of a 5-HT3R antagonist. | BMC biochemistry 20020101 |
Identification of critical residues in loop E in the 5-HT3ASR binding site. | BMC biochemistry 20020101 |
Effects of lerisetron, a new 5-HT3 receptor antagonist, on ipecacuanha-induced emesis in healthy volunteers. | Arzneimittel-Forschung 20020101 |
5-HT(3)R binding of lerisetron: an interdisciplinary approach to drug-Receptor interactions. | Bioorganic & medicinal chemistry letters 20010820 |
Altered disposition and effect of lerisetron in rats with elevated alpha 1-acid glycoprotein levels. | Pharmaceutical research 20010601 |