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Home Other Building Blocks LY 2606368

LY 2606368

CAS No.:
1234015-52-1
Catalog Number:
AG009CCU
Molecular Formula:
C18H19N7O2
Molecular Weight:
365.3892
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥98%
1 week
United States
$187
- +
5mg
98%
1 week
United States
$279
- +
10mg
98%
1 week
United States
$418
- +
25mg
98%
1 week
United States
$779
- +
50mg
98%
1 week
United States
$1098
- +
100mg
98%
1 week
United States
$1723
- +
Product Description
Catalog Number:
AG009CCU
Chemical Name:
LY 2606368
CAS Number:
1234015-52-1
Molecular Formula:
C18H19N7O2
Molecular Weight:
365.3892
MDL Number:
MFCD25977016
IUPAC Name:
5-[[5-[2-(3-aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile
InChI:
InChI=1S/C18H19N7O2/c1-26-14-4-2-5-15(27-7-3-6-19)18(14)13-8-16(25-24-13)23-17-11-21-12(9-20)10-22-17/h2,4-5,8,10-11H,3,6-7,19H2,1H3,(H2,22,23,24,25)
InChI Key:
DOTGPNHGTYJDEP-UHFFFAOYSA-N
SMILES:
NCCCOc1cccc(c1c1[nH]nc(c1)Nc1cnc(cn1)C#N)OC
UNII:
820NH671E6
Properties
Complexity:
499  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
365.16g/mol
Formal Charge:
0
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
365.397g/mol
Monoisotopic Mass:
365.16g/mol
Rotatable Bond Count:
8  
Topological Polar Surface Area:
135A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.4  
Literature
Title Journal
The Checkpoint Kinase 1 Inhibitor Prexasertib Induces Regression of Preclinical Models of Human Neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research 20170801
LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms. Molecular cancer therapeutics 20150901
Properties