Home Other Building Blocks Doxercalciferol-D3

Doxercalciferol-D3

CAS No.:
1217448-46-8
Catalog Number:
AG009CB5
Molecular Formula:
C28H41D3O
Molecular Weight:
399.6668
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
95%
1 week
United States
$973
- +
5mg
95%
1 week
United States
$2807
- +
Product Description
Catalog Number:
AG009CB5
Chemical Name:
Doxercalciferol-D3
CAS Number:
1217448-46-8
Molecular Formula:
C28H41D3O
Molecular Weight:
399.6668
MDL Number:
MFCD11656674
IUPAC Name:
(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]-1-deuterioethylidene]-4-(dideuteriomethylidene)cyclohexan-1-ol
InChI:
InChI=1S/C28H44O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h9-10,12-13,19-20,22,25-27,29H,4,7-8,11,14-18H2,1-3,5-6H3/b10-9+,23-12+,24-13-/t20-,22+,25-,26+,27-,28+/m0/s1/i4D2,13D
InChI Key:
MECHNRXZTMCUDQ-OQGZBSKRSA-N
SMILES:
O[C@H]1CCC(=C([2H])[2H])/C(=C(\C=C\2/CCC[C@]3([C@H]2CC[C@@H]3[C@@H](/C=C/[C@@H](C(C)C)C)C)C)/[2H])/C1
EC Number:
200-014-9
UN Number:
2811
Properties
Complexity:
678  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Defined Bond Stereocenter Count:
3  
Exact Mass:
399.358g/mol
Formal Charge:
0
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
3  
Molecular Weight:
399.677g/mol
Monoisotopic Mass:
399.358g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
20.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
7.4  
Literature
Title Journal
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Generation of potentially bioactive ergosterol-derived products following pulsed ultraviolet light exposure of mushrooms (Agaricus bisporus). Food chemistry 20121115
The vitamin D receptor activator paricalcitol prevents fibrosis and diastolic dysfunction in a murine model of pressure overload. The Journal of steroid biochemistry and molecular biology 20121101
Administered paricalcitol dose and survival in hemodialysis patients: a marginal structural model analysis. Pharmacoepidemiology and drug safety 20121101
In vascular smooth muscle cells paricalcitol prevents phosphate-induced Wnt/β-catenin activation. American journal of physiology. Renal physiology 20121015
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Expression of human CYP27B1 in Escherichia coli and characterization in phospholipid vesicles. The FEBS journal 20121001
Synthesis and biological evaluation of a new vitamin D2 analogue. Bioorganic & medicinal chemistry letters 20121001
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Exposure-clinical response analysis of paricalcitol in patients with chronic kidney disease (stage 5) on hemodialysis or peritoneal dialysis. Journal of clinical pharmacology 20120801
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Changes in fibroblast growth factor 23 during treatment of secondary hyperparathyroidism with alfacalcidol or paricalcitol. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120601
Treatment of vitamin D insufficiency in children and adolescents with inflammatory bowel disease: a randomized clinical trial comparing three regimens. The Journal of clinical endocrinology and metabolism 20120601
Paricalcitol prevents cisplatin-induced renal injury by suppressing apoptosis and proliferation. European journal of pharmacology 20120515
Microalbuminuria, another use for paricalcitol? Our experience in advanced chronic kidney disease. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20120514
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Randomized trial assessing the effects of ergocalciferol administration on circulating FGF23. Clinical journal of the American Society of Nephrology : CJASN 20120401
Serum 24,25-dihydroxyvitamin D concentrations in osteogenesis imperfecta: relationship to bone parameters. The Journal of clinical endocrinology and metabolism 20120401
An update on the screening, diagnosis, management, and treatment of vitamin D deficiency in individuals with cystic fibrosis: evidence-based recommendations from the Cystic Fibrosis Foundation. The Journal of clinical endocrinology and metabolism 20120401
Protective effect of paricalcitol on cyclosporine-induced renal injury in rats. Transplantation proceedings 20120401
Beyond proteinuria: VDR activation reduces renal inflammation in experimental diabetic nephropathy. American journal of physiology. Renal physiology 20120315
Human cytochrome P450scc (CYP11A1) catalyzes epoxide formation with ergosterol. Drug metabolism and disposition: the biological fate of chemicals 20120301
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Ergocalciferol supplementation in children with CKD delays the onset of secondary hyperparathyroidism: a randomized trial. Clinical journal of the American Society of Nephrology : CJASN 20120201
A randomised clinical study of alfacalcidol and paricalcitol. Danish medical journal 20120201
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Converting to doxercalciferol capsules from intravenous paricalcitol or doxercalciferol. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20120101
Left ventricular periostin gene expression is associated with fibrogenesis in experimental renal insufficiency. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120101
Paricalcitol versus ergocalciferol for secondary hyperparathyroidism in CKD stages 3 and 4: a randomized controlled trial. American journal of kidney diseases : the official journal of the National Kidney Foundation 20120101
Effect of paricalcitol and GcMAF on angiogenesis and human peripheral blood mononuclear cell proliferation and signaling. Journal of nephrology 20120101
Effect of combining an ACE inhibitor and a VDR activator on glomerulosclerosis, proteinuria, and renal oxidative stress in uremic rats. American journal of physiology. Renal physiology 20120101
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Characterization of ergocalciferol loaded solid lipid nanoparticles. Journal of food science 20120101
Prospective evaluation of bone markers, parathormone and 1,25-(OH)₂ vitamin D in HIV-positive patients after the initiation of tenofovir/emtricitabine with atazanavir/ritonavir or efavirenz. BMC infectious diseases 20120101
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Doxercalciferol, a pro-hormone of vitamin D, prevents the development of cardiac hypertrophy in rats. Journal of cardiac failure 20111201
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Short-term vitamin D receptor activation increases serum creatinine due to increased production with no effect on the glomerular filtration rate. Kidney international 20111101
Evaluation of the first Ergocalciferol-derived, non hypercalcemic anti-cancer agent MT19c in ovarian cancer SKOV-3 cell lines. Gynecologic oncology 20111101
Short-term effects of vitamin D receptor activation on serum creatinine, creatinine generation, and glomerular filtration. Kidney international 20111101
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Evaluation of bone markers in hypophosphatemic rickets/osteomalacia. Endocrine 20111001
No difference between alfacalcidol and paricalcitol in the treatment of secondary hyperparathyroidism in hemodialysis patients: a randomized crossover trial. Kidney international 20111001
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Preventing progression of cardiac hypertrophy and development of heart failure by paricalcitol therapy in rats. Cardiovascular research 20110901
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Vitamin D(3) is more potent than vitamin D(2) in humans. The Journal of clinical endocrinology and metabolism 20110301
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Supplemental vitamin D and calcium in the management of African Americans with heart failure having hypovitaminosis D. The American journal of the medical sciences 20110201
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Vitamin D supplementation and recombinant human erythropoietin utilization in vitamin D-deficient hemodialysis patients. Journal of nephrology 20110101
Comparative effectiveness of paricalcitol versus cinacalcet for secondary hyperparathyroidism in patients receiving hemodialysis. Nephron. Clinical practice 20110101
Calcitriol and doxercalciferol are equivalent in controlling bone turnover, suppressing parathyroid hormone, and increasing fibroblast growth factor-23 in secondary hyperparathyroidism. Kidney international 20110101
Blockade of Wnt/β-catenin signaling by paricalcitol ameliorates proteinuria and kidney injury. Journal of the American Society of Nephrology : JASN 20110101
Development and optimization of an LC-MS/MS-based method for simultaneous quantification of vitamin D2 , vitamin D3 , 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3. Journal of separation science 20110101
Vitamin D biology: from the discovery to its significance in chronic kidney disease. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20110101
Calcific uremic arteriolopathy while on cinacalcet. Journal of postgraduate medicine 20110101
Vitamin D receptor activation and left ventricular hypertrophy in advanced kidney disease. American journal of nephrology 20110101
Vitamin D and nutritional status are related to bone fractures in alcoholics. Alcohol and alcoholism (Oxford, Oxfordshire) 20110101
Comparative effectiveness of active oral vitamin D agents in patients on peritoneal dialysis. Nephrology news & issues 20110101
Application of ultra-performance liquid chromatography/tandem mass spectrometry for the measurement of vitamin D in foods and nutritional supplements. Journal of AOAC International 20110101
Calcific uremic arteriolopathy treated with cinacalcet, paricalcitol, and autologous growth factors. Journal of cutaneous medicine and surgery 20110101
[Paricalcitol: an ally against proteinuria in diabetic patients?]. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20110101
Validated stability-indicating HPLC method for paricalcitol in pharmaceutical dosage form according to ICH guidelines: application to stability studies. Journal of AOAC International 20110101
Secondary hyperparathyroidism in chronic dialysis patients: results of the Italian FARO survey on treatment and mortality. Blood purification 20110101
Restoring the physiology of vitamin D receptor activation and the concept of selectivity. Contributions to nephrology 20110101
The impact of paricalcitol on left ventricular hypertrophy. Contributions to nephrology 20110101
A randomized controlled trial of vitamin D dosing strategies after acute hip fracture: no advantage of loading doses over daily supplementation. BMC musculoskeletal disorders 20110101
Integrated genomics of ovarian xenograft tumor progression and chemotherapy response. BMC cancer 20110101
[The role of D2 vitamin metabolite paricalcitol in nephroprotective strategy in chronic disease of the kidneys]. Terapevticheskii arkhiv 20110101
Effects of oral paricalcitol on hyperparathyroidism and proteinuria in peritoneal dialysis patients. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20110101
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Paricalcitol, a synthetic vitamin D analog: a candidate for combination therapy with biological agents in rheumatoid arthritis. Medical hypotheses 20101201
Increased fetuin-A levels following treatment with a vitamin D analog. Kidney international 20101201
Stability in the rumen and effect on plasma status of single oral doses of vitamin D and vitamin E in high-yielding dairy cows. Journal of dairy science 20101201
[Cutaneous calciphylaxis]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20101201
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An economic comparison of surgical and medical therapy in patients with secondary hyperparathyroidism--the German perspective. Surgery 20101201
Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): a randomised controlled trial. Lancet (London, England) 20101106
Into the light? Diabetic nephropathy and vitamin D. Lancet (London, England) 20101106
Chondro/osteoblastic and cardiovascular gene modulation in human artery smooth muscle cells that calcify in the presence of phosphate and calcitriol or paricalcitol. Journal of cellular biochemistry 20101101
Association of cumulatively low or high serum calcium levels with mortality in long-term hemodialysis patients. American journal of nephrology 20101101
Identification of a unique subset of 2-methylene-19-nor analogs of vitamin D with comedolytic activity in the rhino mouse. The Journal of investigative dermatology 20101001
Transcriptional activity analysis of promoter region of human PAX9 gene under dexamethasone, retinoic acid, and ergocalciferol treatment in MCF-7 and MDPC23. Cell biochemistry and function 20101001
Effect of paricalcitol on the urinary peptidome of kidney transplant patients. Transplantation proceedings 20101001
Comparison of metabolism of vitamins D2 and D3 in children with nutritional rickets. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20100901
In vitro culture and differentiation of osteoblasts from human umbilical cord blood. Cell and tissue banking 20100801
Therapeutic effects of vitamin D analogs on cardiac hypertrophy in spontaneously hypertensive rats. The American journal of pathology 20100801
Kidney bone disease and mortality in CKD: revisiting the role of vitamin D, calcimimetics, alkaline phosphatase, and minerals. Kidney international. Supplement 20100801
Treatment of secondary hyperparathyroidism in ESRD: a 2-year, single-center crossover study. Kidney international. Supplement 20100801
Effect of high dose ergocalciferol in chronic kidney disease patients with 25-hydroxyvitamin D deficiency. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20100801
Myocardial effects of VDR activators in renal failure. The Journal of steroid biochemistry and molecular biology 20100701
Failure of alphacalcidol (1alpha-hydroxyvitamin D3) in treating nutritional rickets and the biochemical response to ergocalciferol. The Journal of steroid biochemistry and molecular biology 20100701
Bladder rupture following osteoporotic pubic ramus and sacral insufficiency fractures. Age and ageing 20100701
[Studies on the chemical constituents of the flowers of Bupleurum chinese]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100701
Combined vitamin D analog and AT1 receptor antagonist synergistically block the development of kidney disease in a model of type 2 diabetes. Kidney international 20100601
Effect of paricalcitol and cinacalcet on serum phosphate, FGF-23, and bone in rats with chronic kidney disease. American journal of physiology. Renal physiology 20100601
Do calcimimetics directly alter bone remodeling? American journal of physiology. Renal physiology 20100601
Paricalcitol attenuates cyclosporine-induced kidney injury in rats. Kidney international 20100601
Are vitamin D receptor agonists like angiotensin-converting enzyme inhibitors without side effects? Kidney international 20100601
The unsolved cyclosporine-induced kidney injury: is paricalcitol a feasible new renoprotective option? Kidney international 20100601
Cholecalciferol supplementation in hemodialysis patients: effects on mineral metabolism, inflammation, and cardiac dimension parameters. Clinical journal of the American Society of Nephrology : CJASN 20100501
Can vitamin D intake assist in improving the outcome of endodontic treatment for diabetic patients? Medical hypotheses 20100401
New therapies: calcimimetics, phosphate binders and vitamin D receptor activators. Pediatric nephrology (Berlin, Germany) 20100401
Use of 3-hour daily hemodialysis and paricalcitol in patients with severe secondary hyperparathyroidism: A case series. Hemodialysis international. International Symposium on Home Hemodialysis 20100401
Treatment of vitamin D deficiency in CKD patients with ergocalciferol: are current K/DOQI treatment guidelines adequate? Clinical nephrology 20100401
Paricalcitol reduces basal and lipopolysaccharide-induced (LPS) TNF-alpha and IL-8 production by human peripheral blood mononuclear cells. International urology and nephrology 20100301
Transient effectiveness of vitamin D2 therapy in pediatric cystic fibrosis patients. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 20100301
Monitoring vitamin D concentrations in patients with osteoporosis: a clinical perspective. Pharmacotherapy 20100301
Vitamin D deficiency: appropriate replenishment therapies and the effects of vitamin D toxicity. The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20100301
Renoprotective effects of paricalcitol on gentamicin-induced kidney injury in rats. American journal of physiology. Renal physiology 20100201
Vitamin D receptor activators induce an anticalcific paracrine program in macrophages: requirement of osteopontin. Arteriosclerosis, thrombosis, and vascular biology 20100201
A randomized trial of cholecalciferol versus doxercalciferol for lowering parathyroid hormone in chronic kidney disease. Clinical journal of the American Society of Nephrology : CJASN 20100201
On call. After reading your article on multivitamins, I've decided to switch from my old multivitamin to plain vitamin D. But I'm confused by various types of vitamin D. Which kind should I take? Harvard men's health watch 20100201
Pivotal role of paricalcitol in the treatment of calcific uremic arteriolopathy in the presence of a parathyroid adenoma. American journal of kidney diseases : the official journal of the National Kidney Foundation 20100101
Differential effects of paricalcitol and calcitriol on intestinal calcium absorption in hemodialysis patients. American journal of nephrology 20100101
Vitamin D for the treatment of chronic painful conditions in adults. The Cochrane database of systematic reviews 20100101
Calcium balance in dialysis is best managed by adjusting dialysate calcium guided by kinetic modeling of the interrelationship between calcium intake, dose of vitamin D analogues and the dialysate calcium concentration. Blood purification 20100101
The dual vitamin D pathways: considerations for adequate supplementation. Nephrology nursing journal : journal of the American Nephrology Nurses' Association 20100101
Cost Effectiveness of Paricalcitol versus a non-selective vitamin D receptor activator for secondary hyperparathyroidism in the UK: a chronic kidney disease markov model. Clinical drug investigation 20100101
Effects of paricalcitol and enalapril on atherosclerotic injury in mouse aortas. American journal of nephrology 20100101
Screening for vitamin D deficiency in the elderly. Journal of the Mississippi State Medical Association 20100101
[Ultrasound parameter-based response to treatment with new drugs for secondary hyperparathyroidism: a retrospective analysis in a single dialysis center]. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20100101
[Role of paracalcitol in the management of non-dialysis CKD: state of art and... Unmet needs]. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20100101
Serum vitamin D, parathyroid hormone levels, and carotid atherosclerosis. Atherosclerosis 20091201
Vitamin D, nervous system and aging. Psychoneuroendocrinology 20091201
Combination therapy with paricalcitol and trandolapril reduces renal fibrosis in obstructive nephropathy. Kidney international 20091201
Vitamin D: a new hope for chronic kidney disease? Kidney international 20091201
[Why and how correct calcidiol deficiency in haemodialysis patients?]. Nephrologie & therapeutique 20091101
Serum 25-hydroxyvitamin D levels in vitamin D-insufficient hip fracture patients after supplementation with ergocalciferol and cholecalciferol. Bone 20091101
Oral paricalcitol in the treatment of patients with CKD and proteinuria: a randomized trial. American journal of kidney diseases : the official journal of the National Kidney Foundation 20091001
Paricalcitol (19-nor-1,25-dihydroxyvitamin D2) and calcitriol (1,25-dihydroxyvitamin D3) exert potent immunomodulatory effects on dendritic cells and inhibit induction of antigen-specific T cells. Clinical immunology (Orlando, Fla.) 20091001
D-hormone derivatives for the treatment of osteoporosis: from alfacalcidol to eldecalcitol. Mini reviews in medicinal chemistry 20091001
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Protective effect of lysozyme chloride on gastric oxidative stress and hemorrhagic ulcers in severe atherosclerotic rats. Medical science monitor : international medical journal of experimental and clinical research 20071201
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Pamidronate and 1,24(S)-dihydroxyvitamin D2 synergistically inhibit the growth of myeloma, breast and prostate cancer cells. Anticancer research 20050101
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Hammers and nails: a report. Palliative medicine 20041201
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Industry probe. Justice Department subpoenas dialysis providers. Modern healthcare 20041101
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Osteomalacia: recovery of bone density. The New Zealand medical journal 20040618
Hypovitaminosis D in acutely injured pediatric burn patients. Journal of the American Dietetic Association 20040601
Paricalcitol-treated patients experience improved hospitalization outcomes compared with calcitriol-treated patients in real-world clinical settings. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040501
Doxercalciferol safely suppresses PTH levels in patients with secondary hyperparathyroidism associated with chronic kidney disease stages 3 and 4. American journal of kidney diseases : the official journal of the National Kidney Foundation 20040501
[The trend in the development of the active vitamin D3 and its analogues]. Nihon rinsho. Japanese journal of clinical medicine 20040501
19-Nor-1alpha,25-dihydroxyvitamin D2 (paricalcitol) exerts anticancer activity against HL-60 cells in vitro at clinically achievable concentrations. The Journal of steroid biochemistry and molecular biology 20040501
[Vitamin D deficiency/insufficiency in patients with chronic kidney disease stage 3 and 4 -- current concept and its therapeutic strategy]. Clinical calcium 20040501
[Vitamin D supplementation for chronic kidney disease according to the guideline issued by DOQI]. Clinical calcium 20040501
Invited review: beta-lactoglobulin: binding properties, structure, and function. Journal of dairy science 20040401
Effect of vitamin D2- and D3-enriched diets on egg vitamin D content, production, and bird condition during an entire production period. Poultry science 20040301
Vitamin D analogs as therapeutic agents: a clinical study update. Current opinion in investigational drugs (London, England : 2000) 20040301
Effect of vitamins D2 and D3 supplement use on serum 25OHD concentration in elderly women in summer and winter. Calcified tissue international 20040201
Hyperparathyroid hypercalcemic crisis in a patient on calcium and vitamin D supplementation. Clinical nephrology 20040201
Calcimimetics versus vitamin D: what are their relative roles? Blood purification 20040101
Combination study of 1,24(S)-dihydroxyvitamin D2 and chemotherapeutic agents on human breast and prostate cancer cell lines. Anticancer research 20040101
Paricalcitol, calcitriol, and survival of patients undergoing hemodialysis. The New England journal of medicine 20031113
Paricalcitol, calcitriol, and survival of patients undergoing hemodialysis. The New England journal of medicine 20031113
Paricalcitol, calcitriol, and survival of patients undergoing hemodialysis. The New England journal of medicine 20031113
Phase II study of 1alpha-hydroxyvitamin D(2) in the treatment of advanced androgen-independent prostate cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 20030915
1alpha,25-dihydroxyvitamin D(3) (calcitriol) and its analogue, 19-nor-1alpha,25(OH)(2)D(2), potentiate the effects of ionising radiation on human prostate cancer cells. British journal of cancer 20030818
Vitamin D metabolism in a frugivorous nocturnal mammal, the Egyptian fruit bat (Rousettus aegyptiacus). General and comparative endocrinology 20030801
Survival of patients undergoing hemodialysis with paricalcitol or calcitriol therapy. The New England journal of medicine 20030731
Paricalcitol as compared with calcitriol in patients undergoing hemodialysis. The New England journal of medicine 20030731
Prevention and treatment of secondary hyperparathyroidism: still a challenge for the nephrologist? Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030701
Selective inhibition of mammalian DNA polymerase alpha by vitamin D2 and D3. Journal of pharmacological sciences 20030701
Vitamin D2 analog 19-nor-1,25-dihydroxyvitamin D2: antitumor activity against leukemia, myeloma, and colon cancer cells. Journal of the National Cancer Institute 20030618
Efficacy of 19-Nor-1,25-(OH)2D2 in the prevention and treatment of hyperparathyroid bone disease in experimental uremia. Kidney international 20030601
A strategy for the treatment of calcific uremic arteriolopathy (calciphylaxis) employing a combination of therapies. Clinical nephrology 20030601
Effect of doxercalciferol (1alpha-hydroxyvitamin D2) on PTH, bone turnover and bone mineral density in a hemodialysis patient with persistent secondary hyperparathyroidism post parathyroidectomy. Clinical nephrology 20030601
Long-term therapy with paricalcitol for secondary hyperparathyroidism in hemodialysis patients. The International journal of artificial organs 20030601
Growth inhibition and differentiation in human prostate carcinoma cells induced by the vitamin D analog 1alpha,24-dihydroxyvitamin D2. The Prostate 20030515
A review of intravenous versus oral vitamin D hormone therapy in hemodialysis patients. Clinical nephrology 20030501
Experimental aortic valve stenosis in rabbits. Journal of the American College of Cardiology 20030402
Paricalcitol versus calcitriol in the treatment of secondary hyperparathyroidism. Kidney international 20030401
Pharmacokinetics of doxercalciferol, a new vitamin D analogue that lowers parathyroid hormone. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030401
The renal dietitian's role in managing hyperphosphatemia and secondary hyperparathyroidism in dialysis patients: a national survey. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20030401
Toxicity and dose-response studies of 1-alpha hydroxyvitamin D2 in LH-beta-tag transgenic mice. Ophthalmology 20030401
Competitive effect of vitamin D2 and Ca2+ on phospholipid model membranes: an FTIR study. Chemistry and physics of lipids 20030401
Synthesis of C-19-functionalized 1alpha-hydroxyvitamin D(2) analogues via ring-closing metathesis. Organic letters 20030306
[Preparation of complex chitosan microcapsule and its application in controlled release of vitamin D2]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20030301
Rat cytochrome P450C24 (CYP24) does not metabolize 1,25-dihydroxyvitamin D2 to calcitroic acid. Journal of cellular biochemistry 20030201
19-nor-1alpha,25-dihydroxyvitamin D(2) (paricalcitol): effects on clonal proliferation, differentiation, and apoptosis in human leukemic cell lines. Journal of cancer research and clinical oncology 20030101
[Differential effect of vitamin D analogues on the proliferation of vascular smooth muscle cells]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20030101
[Mechanism of uremic osteodystrophy and prevention of hyperparathyroidism in the uremic patient]. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20030101
Effects of 'non-calcaemic' vitamin D analogues on 24-hydroxylase expression in MG-63 osteoblast-like cells. Nephron. Physiology 20030101
[Effect of natural enterosorbents in experimental liver disorders]. Eksperimental'naia i klinicheskaia farmakologiia 20030101
[Ergocalciferol Reference Standard (Control 031) of National Institute of Health Sciences]. Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 20030101
Severe hyperparathyroidism despite paricalcitol therapy: one-year follow-up. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20030101
Preparation of chitosan/ethylcellulose complex microcapsule and its application in controlled release of vitamin D2. Biomaterials 20021201
Differential effects of acute administration of 19-Nor-1,25-dihydroxy-vitamin D2 and 1,25-dihydroxy-vitamin D3 on serum calcium and phosphorus in hemodialysis patients. American journal of kidney diseases : the official journal of the National Kidney Foundation 20021201
First place winner. Recurrent febrile seizures: an unusual presentation of nutritional rickets. The Journal of emergency medicine 20021101
Differential effects of 19-nor-1,25-(OH)(2)D(2) and 1alpha-hydroxyvitamin D(2) on calcium and phosphorus in normal and uremic rats. Kidney international 20021001
Low rate of compliance with ergocalciferol therapy in vitamin-D-deficient patients with hip fracture. The Medical journal of Australia 20020902
Phase I trial of 1alpha-hydroxyvitamin d(2) in patients with hormone refractory prostate cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 20020901
Vitamin D analogs, a new treatment for retinoblastoma: The first Ellsworth Lecture. Ophthalmic genetics 20020901
Distal calcific uremic arteriolopathy in a hemodialysis patient responds to lowering of Ca x P product and aggressive wound care. Clinical nephrology 20020901
Synthesis and antiproliferative activity of side-chain unsaturated and homologated analogs of 1,25-dihydroxyvitamin D(2). (24E)-(1S)-24-Dehydro-24a-homo-1,25-dihydroxyergocalciferol and congeners. Steroids 20020801
Oral doxercalciferol therapy for secondary hyperparathyroidism in a peritoneal dialysis patient. Clinical nephrology 20020801
Cats discriminate between cholecalciferol and ergocalciferol. Journal of animal physiology and animal nutrition 20020801
Use of vitamin D(4) analogs to investigate differences in hepatic and target cell metabolism of vitamins D(2) and D(3). Biochimica et biophysica acta 20020711
Toxicity and dose-response studies of 1alpha-hydroxyvitamin D2 in a retinoblastoma xenograft model. Archives of ophthalmology (Chicago, Ill. : 1960) 20020501
Differential effects of 19-nor-1,25-dihydroxyvitamin D(2) and 1,25-dihydroxyvitamin D(3) on intestinal calcium and phosphate transport. The Journal of laboratory and clinical medicine 20020501
Vitamin D deficiency and multicultural Australia. The Medical journal of Australia 20020304
Pathological long-bone fractures in residents with cerebral palsy in a long-term care facility in South Africa. Developmental medicine and child neurology 20020201
Vitamin D analogs for the treatment of secondary hyperparathyroidism. Blood purification 20020101
Comparative review of the pharmacokinetics of vitamin D analogues. Seminars in dialysis 20020101
Vitamin D analogues for secondary hyperparathyroidism. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020101
Toxicity and dose-response studies of 1 alpha-hydroxyvitamin D2 in LH beta-Tag transgenic mice. Transactions of the American Ophthalmological Society 20020101
Derivatives of vitamins D2 and D3 activate three MAPK pathways and upregulate pRb expression in differentiating HL60 cells. Cell cycle (Georgetown, Tex.) 20020101
Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3. Molecular pharmacology 20011201
Strategies to minimize bone disease in renal failure. American journal of kidney diseases : the official journal of the National Kidney Foundation 20011201
p21WAF1 and TGF-alpha mediate parathyroid growth arrest by vitamin D and high calcium. Kidney international 20011201
Severe secondary hyperparathyroidism. Nephrology nursing journal : journal of the American Nephrology Nurses' Association 20011201
Vitamin D analogues for the management of secondary hyperparathyroidism. American journal of kidney diseases : the official journal of the National Kidney Foundation 20011101
Paricalcitol in dialysis patients with calcitriol-resistant secondary hyperparathyroidism. American journal of kidney diseases : the official journal of the National Kidney Foundation 20011101
Suppression of parathyroid hormone secretion in hemodialysis patients: comparison of paricalcitol with calcitriol. American journal of kidney diseases : the official journal of the National Kidney Foundation 20011101
Paricalcitol dosing according to body weight or severity of hyperparathyroidism: a double-blind, multicenter, randomized study. American journal of kidney diseases : the official journal of the National Kidney Foundation 20011101
[Hypovitaminosis D: a veiled diagnosis]. Nederlands tijdschrift voor geneeskunde 20011027
A placebo-controlled trial to evaluate immunomodulatory effects of paricalcitol. American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001
A long-term, multicenter study of the efficacy and safety of paricalcitol in end-stage renal disease. Clinical nephrology 20011001
Provitamins and vitamins D₂and D₃in Cladina spp. over a latitudinal gradient: possible correlation with UV levels. Journal of photochemistry and photobiology. B, Biology 20010901
Calcitroic acid is a major catabolic metabolite in the metabolism of 1 alpha-dihydroxyvitamin D(2). Archives of biochemistry and biophysics 20010801
Double bond in the side chain of 1alpha,25-dihydroxy-22-ene-vitamin D(3) is reduced during its metabolism: studies in chronic myeloid leukemia (RWLeu-4) cells and rat kidney. The Journal of steroid biochemistry and molecular biology 20010801
Relative potencies of 1,25-(OH)(2)D(3) and 19-Nor-1,25-(OH)(2)D(2) on inducing differentiation and markers of bone formation in MG-63 cells. Journal of the American Society of Nephrology : JASN 20010701
1alpha-hydroxyvitamin D2 is less toxic but not bone selective relative to 1alpha-hydroxyvitamin D3 in ovariectomized rats. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010401
Effect of 1alpha,25-dihydroxyvitamin D3 and 24R,25-dihydroxyvitamin D3 on metalloproteinase activity and cell maturation in growth plate cartilage in vivo. Endocrine 20010401
In vitro metabolism of 19-nor-1alpha, 25-(OH)2D2 in cultured cell lines: inducible synthesis of lipid- and water-soluble metabolites. Archives of biochemistry and biophysics 20010315
Metabolic and endocrine effects of metabolic acidosis in humans. Swiss medical weekly 20010310
Efficacy and side effects of intermittent intravenous and oral doxercalciferol (1alpha-hydroxyvitamin D(2)) in dialysis patients with secondary hyperparathyroidism: a sequential comparison. American journal of kidney diseases : the official journal of the National Kidney Foundation 20010301
[The stereocontrolled synthesis of 1-acetylenyl-3-tert-butyldiphenylsilyloxy-exo-bicyclo [3. 1. 0] hexane]. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20010301
[Advantages of active vitamin D metabolites in the treatment of osteoporosis as compared with calciferol]. Vnitrni lekarstvi 20010201
The effects of 1alpha,24(S)-dihydroxyvitamin D(2) analog on cancer cell proliferation and cytokine expression. Steroids 20010101
Effects of vitamins on hepatic nuclear binding of L-tryptophan. Amino acids 20010101
New vitamin D analogs. Seminars in dialysis 20010101
Vitamin d deficiency in breast-fed toddlers. Journal of pediatric orthopedics 20010101
[Ergocalciferol Reference Standard (Control 001) of National Institute of Health Sciences]. Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 20010101
Comparison of the relative effects of 1,24-dihydroxyvitamin D(2) [1, 24-(OH)(2)D(2)], 1,24-dihydroxyvitamin D(3) [1,24-(OH)(2)D(3)], and 1,25-dihydroxyvitamin D(3) [1,25-(OH)(2)D(3)] on selected vitamin D-regulated events in the rat. Biochemical pharmacology 20000901
Calcitriol directly sensitizes renal tubular cells to ATP-depletion- and iron-mediated attack. The American journal of pathology 19990601
Comparative effects of vitamin K2 and vitamin E on experimental arteriosclerosis. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 19990101
X-linked hypophosphatemia: normal renal function despite medullary nephrocalcinosis 25 years after transient vitamin D2-induced renal azotemia. Bone 19971201
Progressively increased serum 1,25-dihydroxyvitamin D2 concentration in a hypoparathyroid patient with protracted hypercalcemia due to vitamin D2 intoxication. Endocrine journal 19940801
Vitamin D2-induced hypercalcemia in rat lens. Investigative ophthalmology & visual science 19860301
Vitamin D2-induced arteriosclerosis in spontaneously hypertensive rats and protection by diltiazem, a calcium antagonist. Nihon juigaku zasshi. The Japanese journal of veterinary science 19840601
Reversal of vitamin-D2-induced hypercalciuria by chlorothiazide. Pediatric research 19830201
Prevention of osteonecrosis following renal transplantation by using vitamin D2 (ergocalciferol). Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association 19830101
Vitamin D3 toxicity in dairy cows. Journal of dairy science 19820501
Pharmacology and therapeutic use of vitamin D and its analogues. Drugs 19810401
Inhibition of vitamin D2-induced arteriosclerosis in rats by depletion of complement with cobra venom factor. Artery 19800101
Does somatostatin in each organ act specifically on that particular organ? The Tohoku journal of experimental medicine 19790901
Myopathy associated with anticonvulsant osteomalacia. British medical journal 19731201
A comparison of the toxicity of ergocalciferol and cholecalciferol in rhesus monkeys (Macaca mulatta). The Journal of nutrition 19720801
Chlorothiazide-induced hypercalcemia in juvenile osteoporosis and hyperparathyroidism. The New England journal of medicine 19690710
The effect of cortisone on vitamin D2-induced nephrocalcinosis in the rat. Clinical science 19570201
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