Home Other Building Blocks 4-HYDROXY PROPRANOLOL HCL

4-HYDROXY PROPRANOLOL HCL

CAS No.:
14133-90-5
Catalog Number:
AG009BPQ
Molecular Formula:
C16H22ClNO3
Molecular Weight:
311.8038
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥95%
1 week
United States
$105
- +
5mg
≥95%
1 week
United States
$287
- +
10mg
≥95%
1 week
United States
$471
- +
Product Description
Catalog Number:
AG009BPQ
Chemical Name:
4-HYDROXY PROPRANOLOL HCL
CAS Number:
14133-90-5
Molecular Formula:
C16H22ClNO3
Molecular Weight:
311.8038
MDL Number:
MFCD06656370
IUPAC Name:
4-[2-hydroxy-3-(propan-2-ylamino)propoxy]naphthalen-1-ol;hydrochloride
InChI:
InChI=1S/C16H21NO3.ClH/c1-11(2)17-9-12(18)10-20-16-8-7-15(19)13-5-3-4-6-14(13)16;/h3-8,11-12,17-19H,9-10H2,1-2H3;1H
InChI Key:
ROUJENUXWIFONU-UHFFFAOYSA-N
SMILES:
OC(COc1ccc(c2c1cccc2)O)CNC(C)C.Cl
Properties
Complexity:
285  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
311.129g/mol
Formal Charge:
0
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
311.806g/mol
Monoisotopic Mass:
311.129g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
61.7A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Potential bias and mitigations when using stable isotope labeled parent drug as internal standard for LC-MS/MS quantitation of metabolites. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101201
Comparative study of the oxidation of propranolol enantiomers in hepatic and small intestinal microsomes from cynomolgus and marmoset monkeys. Chemico-biological interactions 20100105
Simultaneous determination of propranolol and 4-hydroxy propranolol in human plasma by solid phase extraction and liquid chromatography/electrospray tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis 20091205
Enantioselective analysis of propranolol and 4-hydroxypropranolol by CE with application to biotransformation studies employing endophytic fungi. Electrophoresis 20091101
Box-Behnken design for the optimization of an enantioselective method for the simultaneous analysis of propranolol and 4-hydroxypropranolol by CE. Electrophoresis 20090801
Involvement of SULT1A3 in elevated sulfation of 4-hydroxypropranolol in Hep G2 cells pretreated with beta-naphthoflavone. Biochemical pharmacology 20050315
Potent antioxidant properties of 4-hydroxyl-propranolol. The Journal of pharmacology and experimental therapeutics 20040101
Inactivation of rat cytochrome P450 2D enzyme by a further metabolite of 4-hydroxypropranolol, the major and active metabolite of propranolol. Biological & pharmaceutical bulletin 20010901
High-performance liquid chromatographic analysis of the sulfation of 4-hydroxypropranolol enantiomers by monkey liver cytosol. Chirality 20010101
Properties