Name: Name:Ldn-212854
Brand: Angene
SKU: AG009BPK
Rating: 90 (10 reviews)

Ldn-212854

CAS No.:

1432597-26-6

Catalog Number:

AG009BPK

Molecular Formula:

C25H22N6

Molecular Weight:

406.4824

Pack Size

Purity

Availability

Location

Price(USD)

Quantity

1mg

≥98%

1 week

United States

$96

- +

5mg

≥98%

1 week

United States

$222

- +

10mg

≥98%

1 week

United States

$368

- +

25mg

99%

1 week

United States

$682

- +

50mg

99%

1 week

United States

$1182

- +

Product Description

Catalog Number:

AG009BPK

Chemical Name:

Ldn-212854

CAS Number:

1432597-26-6

Molecular Formula:

C25H22N6

Molecular Weight:

406.4824

MDL Number:

MFCD28099808

IUPAC Name:

5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline

InChI:

InChI=1S/C25H22N6/c1-3-21(22-4-2-10-27-24(22)5-1)23-16-29-31-17-19(15-28-25(23)31)18-6-8-20(9-7-18)30-13-11-26-12-14-30/h1-10,15-17,26H,11-14H2

InChI Key:

BBDGBGOVJPEFBT-UHFFFAOYSA-N

SMILES:

N1CCN(CC1)c1ccc(cc1)c1cnc2n(c1)ncc2c1cccc2c1cccn2

Properties

Complexity:

587

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Exact Mass:

406.191g/mol

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Molecular Weight:

406.493g/mol

Monoisotopic Mass:

406.191g/mol

Rotatable Bond Count:

Topological Polar Surface Area:

58.4A^2

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

XLogP3:

3.3

Literature

Title	Journal
Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants.	Journal of medicinal chemistry 20141009
Synthesis and structure-activity relationships of a novel and selective bone morphogenetic protein receptor (BMP) inhibitor derived from the pyrazolo[1.5-a]pyrimidine scaffold of dorsomorphin: the discovery of ML347 as an ALK2 versus ALK3 selective MLPCN probe.	Bioorganic & medicinal chemistry letters 20130601

Properties