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BIX02189

CAS No.:
1265916-41-3
Catalog Number:
AG009BPG
Molecular Formula:
Molecular Weight:
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$182
- +
10mg
99%
1 week
United States
$251
- +
50mg
99%
1 week
United States
$682
- +
100mg
99%
1 week
United States
$1098
- +
Product Description
Catalog Number:
AG009BPG
Chemical Name:
BIX02189
CAS Number:
1265916-41-3
MDL Number:
MFCD18074528
IUPAC Name:
3-[N-[3-[(dimethylamino)methyl]phenyl]-C-phenylcarbonimidoyl]-2-hydroxy-N,N-dimethyl-1H-indole-6-carboxamide
InChI:
InChI=1S/C27H28N4O2/c1-30(2)17-18-9-8-12-21(15-18)28-25(19-10-6-5-7-11-19)24-22-14-13-20(27(33)31(3)4)16-23(22)29-26(24)32/h5-16,29,32H,17H2,1-4H3
InChI Key:
ZGXOBLVQIVXKEB-UHFFFAOYSA-N
Properties
Complexity:
688  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
440.221g/mol
Formal Charge:
0
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
440.547g/mol
Monoisotopic Mass:
440.221g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
71.9A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.5  
Literature
Title Journal
Laminar flow activation of ERK5 protein in vascular endothelium leads to atheroprotective effect via NF-E2-related factor 2 (Nrf2) activation. The Journal of biological chemistry 20121123
Cadmium activates extracellular signal-regulated kinase 5 in HK-2 human renal proximal tubular cells. Biochemical and biophysical research communications 20120511
Identification of pharmacological inhibitors of the MEK5/ERK5 pathway. Biochemical and biophysical research communications 20081205
Properties