CA-074
| Title | Journal |
|---|---|
| Cathepsin B regulates the appearance and severity of mercury-induced inflammation and autoimmunity. | Toxicological sciences : an official journal of the Society of Toxicology 20141201 |
| Cathepsin B inhibition limits bone metastasis in breast cancer. | Cancer research 20120301 |
| An alternative metabolic pathway of amyloid precursor protein C-terminal fragments via cathepsin B in a human neuroglioma model. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20111001 |
| Cathepsin B-mediated autophagy flux facilitates the anthrax toxin receptor 2-mediated delivery of anthrax lethal factor into the cytoplasm. | The Journal of biological chemistry 20100115 |
| [Structure-based drug development and medical/biological application of cathepsin specific inhibitors]. | Seikagaku. The Journal of Japanese Biochemical Society 20091101 |
| Intra- versus extracellular effects of microglia-derived cysteine proteases in a conditioned medium transfer model. | Journal of neurochemistry 20090901 |
| Identification of 3-acetyl-2-aminoquinolin-4-one as a novel, nonpeptidic scaffold for specific calpain inhibitory activity. | Journal of medicinal chemistry 20090514 |
| Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells. | The Journal of biological chemistry 20090327 |
| [The experimental study of specific inhibitor-CA-074Me of Cathepsin B suppressing retinal neovascularization]. | [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20080301 |
| Cathepsins B, L and D in inflammatory bowel disease macrophages and potential therapeutic effects of cathepsin inhibition in vivo. | Clinical and experimental immunology 20061001 |
| Identification and discrimination of extracellularly active cathepsins B and L in high-invasive melanoma cells. | Analytical biochemistry 20060601 |
| High-temperature liquid chromatography coupled on-line to a continuous-flow biochemical screening assay with electrospray ionization mass spectrometric detection. | Analytical chemistry 20051215 |
| Endosomal proteolysis of insulin-like growth factor-I at its C-terminal D-domain by cathepsin B. | FEBS letters 20050815 |
| The solution structure of the Josephin domain of ataxin-3: structural determinants for molecular recognition. | Proceedings of the National Academy of Sciences of the United States of America 20050726 |
| Differential susceptibility of metastatic and primary oral cancer cells to TRAIL-induced apoptosis. | International journal of oncology 20050101 |
| Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft. | The Biochemical journal 20040715 |
| Cathepsin L is crucial for a Th1-type immune response during Leishmania major infection. | Microbes and infection 20040401 |
| Significant accumulations of cathepsin B and prolylendopeptidase in inflammatory focus of delayed-type hypersensitivity induced by Mycobacterium tuberculosis in mice. | Biochemical and biophysical research communications 20040326 |
| Cysteine proteases and cell differentiation: excystment of the ciliated protist Sterkiella histriomuscorum. | Eukaryotic cell 20031201 |
| Cathepsin B in osteoblasts. | Biochimica et biophysica acta 20030502 |
| Primate neurons show different vulnerability to transient ischemia and response to cathepsin inhibition. | Acta neuropathologica 20020901 |
| Structural basis for development of cathepsin B-specific noncovalent-type inhibitor: crystal structure of cathepsin B-E64c complex. | Biochimica et biophysica acta 20020603 |
| CA-074, but not its methyl ester CA-074Me, is a selective inhibitor of cathepsin B within living cells. | Biological chemistry 20020101 |
| Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha-mediated hepatocyte apoptosis and liver injury: implications for therapeutic applications. | The American journal of pathology 20011201 |