BQ-123
Title | Journal |
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Induction of endothelium-dependent constriction of mesenteric arteries in endotoxemic hypotensive shock. | British journal of pharmacology 20160401 |
BQ-123 prevents LPS-induced preterm birth in mice via the induction of uterine and placental IL-10. | Toxicology and applied pharmacology 20150201 |
Activation of the endothelin system mediates pathological angiogenesis during ischemic retinopathy. | The American journal of pathology 20141101 |
Selective ET(A) receptor blockade protects against cisplatin-induced acute renal failure in male rats. | European journal of pharmacology 20140505 |
Vascular endothelial growth factor-C modulates proliferation and chemoresistance in acute myeloid leukemic cells through an endothelin-1-dependent induction of cyclooxygenase-2. | Biochimica et biophysica acta 20140201 |
Interplay between endothelin and erythropoietin in astroglia: the role in protection against hypoxia. | International journal of molecular sciences 20140201 |
Endothelin-1 increases superoxide production in human coronary artery bypass grafts. | Life sciences 20121015 |
The adipokine chemerin augments vascular reactivity to contractile stimuli via activation of the MEK-ERK1/2 pathway. | Life sciences 20121015 |
The influence of ETA and ETB receptor blockers on LPS-induced oxidative stress and NF-κB signaling pathway in heart. | General physiology and biophysics 20120901 |
Cathepsin E induces itch-related response through the production of endothelin-1 in mice. | European journal of pharmacology 20120705 |
Agonist-dependent modulation of arterial endothelinA receptor function. | British journal of pharmacology 20120701 |
Endothelin 1-dependent neurovascular dysfunction in chronic intermittent hypoxia. | Hypertension (Dallas, Tex. : 1979) 20120701 |
Blocking endothelin-B receptors rescues retinal ganglion cells from optic nerve injury through suppression of neuroinflammation. | Investigative ophthalmology & visual science 20120608 |
Ouabain stimulates atrial natriuretic peptide secretion via the endothelin-1/ET(B) receptor-mediated pathway in beating rabbit atria. | Life sciences 20120522 |
Elevated endothelin-1 vasoconstrictor tone in prehypertensive adults. | The Canadian journal of cardiology 20120501 |
EndothelinA-endothelinB receptor cross-talk in rat basilar artery in situ. | Naunyn-Schmiedeberg's archives of pharmacology 20120401 |
Modulation by endothelin-1 of spontaneous activity and membrane currents of atrioventricular node myocytes from the rabbit heart. | PloS one 20120101 |
Fluorescence correlation spectroscopy in drug discovery: study of Alexa532-endothelin 1 binding to the endothelin ETA receptor to describe the pharmacological profile of natural products. | TheScientificWorldJournal 20120101 |
Endothelin-1 stimulates small artery VCAM-1 expression through p38MAPK-dependent neutral sphingomyelinase. | Journal of vascular research 20120101 |
Pharmacological differences of endothelin receptors-mediated modulation in cultured interstitial cells of Cajal from the murine small and large intestine. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101 |
Endothelin-1 in paraventricular nucleus modulates cardiac sympathetic afferent reflex and sympathetic activity in rats. | PloS one 20120101 |
Age-associated alterations in retinal arteriole reactivity to endothelin-1 differ between the sexes. | Mechanisms of ageing and development 20120101 |
ETA and ETB receptors are expressed in vascular adventitial fibroblasts. | American journal of physiology. Heart and circulatory physiology 20111201 |
Endothelin-1 promotes osteosarcoma cell invasion and survival against cisplatin-induced apoptosis. | Clinical orthopaedics and related research 20111101 |
Endothelin-induced changes in blood flow in STZ-diabetic and non-diabetic rats: relation to nitric oxide synthase and cyclooxygenase inhibition. | The journal of physiological sciences : JPS 20111101 |
Low-intensity interval exercise training attenuates coronary vascular dysfunction and preserves Ca²⁺-sensitive K⁺ current in miniature swine with LV hypertrophy. | American journal of physiology. Heart and circulatory physiology 20111001 |
Irregular electrical activation of intrinsic cardiac adrenergic cells increases catecholamine-synthesizing enzymes. | Biochemical and biophysical research communications 20110930 |
Exogenous ghrelin improves blood flow distribution in pulmonary hypertension-assessed using synchrotron radiation microangiography. | Pflugers Archiv : European journal of physiology 20110901 |
Endothelin-1 vasoconstriction and the age-related decline in endothelium-dependent vasodilatation in men. | Clinical science (London, England : 1979) 20110601 |
Tobacco-associated pulmonary vascular dysfunction in smokers: role of the ET-1 pathway. | American journal of physiology. Lung cellular and molecular physiology 20110601 |
Cyclosporine A-induced acute hepatotoxicity in guinea pigs is associated with endothelin-mediated decrease in local hepatic blood flow. | Life sciences 20110425 |
20-Hydroxyeicosatetraenoic acid synthesis is increased in human neutrophils and platelets by angiotensin II and endothelin-1. | American journal of physiology. Heart and circulatory physiology 20110401 |
Effect of avosentan (SPP-301) in porcine ciliary arteries. | Current eye research 20110201 |
From a molecular biological viewpoint, does endothelin type A receptor antagonist therapy reduce diabetes-induced testicular damage in rats? | Urology 20110101 |
Endothelin-A receptor antagonists prevent amyloid-β-induced increase in ETA receptor expression, oxidative stress, and cognitive impairment. | Journal of Alzheimer's disease : JAD 20110101 |
Nociceptive tolerance is improved by bradykinin receptor B1 antagonism and joint morphology is protected by both endothelin type A and bradykinin receptor B1 antagonism in a surgical model of osteoarthritis. | Arthritis research & therapy 20110101 |
Protective effects of endothelin-A receptor antagonist BQ123 against LPS-induced oxidative stress in lungs. | Pharmacological reports : PR 20110101 |
Glial response to lipopolysaccharide: possible role of endothelins. | Peptides 20101201 |
Evidence that apoptotic signalling in hypertrophic cardiomyocytes is determined by mitochondrial pathways involving protein kinase Cδ. | Clinical and experimental pharmacology & physiology 20101201 |
Endothelin receptor antagonist BQ-123 ameliorates myocardial ischemic-reperfusion injury in rats: a hemodynamic, biochemical, histopathological and electron microscopic evidence. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20101101 |
Molecular signaling of pruritus induced by endothelin-1 in mice. | Experimental biology and medicine (Maywood, N.J.) 20101101 |
Endothelin-A receptor antagonist BQ123 potentiates acetaminophen induced hypothermia and reduces infarction following focal cerebral ischemia in rats. | European journal of pharmacology 20101010 |
Effects of cardiopulmonary bypass on endothelin-1-induced contraction and signaling in human skeletal muscle microcirculation. | Circulation 20100914 |
Inhibition of endothelin-1 receptors improves impaired nitric oxide synthase-dependent dilation of cerebral arterioles in type-1 diabetic rats. | Microcirculation (New York, N.Y. : 1994) 20100801 |
Increased endothelial exocytosis and generation of endothelin-1 contributes to constriction of aged arteries. | Circulation research 20100723 |
Endothelin-A receptor antagonism attenuates carcinoma-induced pain through opioids in mice. | The journal of pain : official journal of the American Pain Society 20100701 |
Endothelin-1-induced contractile responses of human coronary arterioles via endothelin-A receptors and PKC-alpha signaling pathways. | Surgery 20100601 |
Simvastatin stimulates production of the antiapoptotic protein Bcl-2 via endothelin-1 and NFATc3 in SH-SY5Y cells. | Molecular neurobiology 20100601 |
Activation of endothelin A receptors contributes to impaired responsiveness of renal mechanosensory nerves in congestive heart failure. | Canadian journal of physiology and pharmacology 20100601 |
Acute effects of endothelin receptor antagonists on hepatic hemodynamics of cirrhotic and noncirrhotic rats. | Canadian journal of physiology and pharmacology 20100601 |
Endothelium-derived endothelin-1. | Pflugers Archiv : European journal of physiology 20100501 |
Regulation of glucose uptake by endothelin-1 in human skeletal muscle in vivo and in vitro. | The Journal of clinical endocrinology and metabolism 20100501 |
[The mechanism and pulmonary-protective effects of endothelin-1 receptor antagonist in chronic obstructive pulmonary diseases rat model]. | Zhonghua nei ke za zhi 20100501 |
The vasodilatory effect of juxta-arteriolar microinjection of endothelinA receptor inhibitor in healthy and acute branch retinal vein occlusion minipig retinas. | Investigative ophthalmology & visual science 20100401 |
Endothelin-1 receptor antagonists prevent the development of pulmonary emphysema in rats. | The European respiratory journal 20100401 |
Attenuation of Doxorubicin-induced cardiomyopathy by endothelin-converting enzyme-1 ablation through prevention of mitochondrial biogenesis impairment. | Hypertension (Dallas, Tex. : 1979) 20100301 |
Sex differences in endothelin-1-mediated vasoconstrictor tone in middle-aged and older adults. | American journal of physiology. Regulatory, integrative and comparative physiology 20100201 |
Diabetes-associated changes and role of N epsilon-(carboxymethyl)lysine in big ET-1-induced coronary vasoconstriction. | Peptides 20100201 |
Role of endogenous ET-1 in the regulation of myocardial blood flow in lean and obese humans. | Obesity (Silver Spring, Md.) 20100101 |
Potential of endothelin-1 and vasopressin antagonists for the treatment of congestive heart failure. | Heart failure reviews 20100101 |
Production and binding of endothelin-2 (EDN2) in the rat ovary: endothelin receptor subtype A (EDNRA)-mediated contraction. | Reproduction, fertility, and development 20100101 |
Ablation of transient receptor potential vanilloid 1 abolishes endothelin-induced increases in afferent renal nerve activity: mechanisms and functional significance. | Hypertension (Dallas, Tex. : 1979) 20091201 |
Endothelin-1 induces the expression of C-reactive protein in rat vascular smooth muscle cells. | Biochemical and biophysical research communications 20091120 |
[Cardioprotection of ramipril and BQ-123 against myocardial ischemia/reperfusion injury in vivo in rats]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20091101 |
Dietary sodium modulates the interaction between efferent renal sympathetic nerve activity and afferent renal nerve activity: role of endothelin. | American journal of physiology. Regulatory, integrative and comparative physiology 20090801 |
Role of ET(A) and ET(B) endothelin receptors on endothelin-1-induced potentiation of nociceptive and thermal hyperalgesic responses evoked by capsaicin in rats. | Neuroscience letters 20090703 |
Functional and molecular characterization of the endothelin system in retinal arterioles. | Investigative ophthalmology & visual science 20090701 |
Blood pressure-independent reduction in proteinuria and arterial stiffness after acute endothelin-a receptor antagonism in chronic kidney disease. | Hypertension (Dallas, Tex. : 1979) 20090701 |
Angiotensin II-induced increase in myocardial distensibility and its modulation by the endocardial endothelium in the rabbit heart. | Experimental physiology 20090601 |
Improved endothelial function after endothelin receptor blockade in patients with systemic sclerosis. | Arthritis and rheumatism 20090601 |
Involvement of NO and MEK/ERK pathway in enhancement of endothelin-1-induced mesenteric artery contraction in later-stage type 2 diabetic Goto-Kakizaki rat. | American journal of physiology. Heart and circulatory physiology 20090501 |
Vehicular emissions induce vascular MMP-9 expression and activity associated with endothelin-1-mediated pathways. | Arteriosclerosis, thrombosis, and vascular biology 20090401 |
The effect of endothelin-1 on alveolar fluid clearance and pulmonary edema formation in the rat. | Anesthesia and analgesia 20090101 |
Normothermic perfusion of ischaemic porcine kidneys: an evaluation of ex vivo function and endothelin receptor antagonism. | Journal of nephrology 20090101 |
Selective endothelin A-receptor blockade attenuates coronary microvascular dysfunction after coronary stenting in patients with type 2 diabetes. | Vascular health and risk management 20090101 |
Endothelin A receptor antagonist modulates lymphocyte and eosinophil infiltration, hyperreactivity and mucus in murine asthma. | International immunopharmacology 20081220 |
Molecular analysis of cocaine-induced endothelial dysfunction: role of endothelin-1 and nitric oxide. | Cardiovascular toxicology 20081201 |
Regulation of glial inflammatory mediators synthesis: possible role of endothelins. | Peptides 20081201 |
Adenosine 5'-tetraphosphate is a highly potent purinergic endothelium-derived vasoconstrictor. | Circulation research 20081107 |
Endothelium-derived vasoconstriction by purines and pyrimidines. | Circulation research 20081107 |
Role of nitric oxide in regulation of retinal blood flow in response to hyperoxia in cats. | Investigative ophthalmology & visual science 20081001 |
Pharmacological characterization of 3-azabicyclo[3,2,1] octane-1-yl-l-leucyl-d-tryptophanyl-d-4-Cl-phenylalanine: A novel ET(A) receptor-selective antagonist. | Pulmonary pharmacology & therapeutics 20081001 |
The endothelin-converting enzyme-1/endothelin-1 pathway plays a critical role in inflammation-associated premature delivery in a mouse model. | The American journal of pathology 20081001 |
Endothelins modulate inflammatory reaction in zymosan-induced arthritis: participation of LTB4, TNF-alpha, and CXCL-1. | Journal of leukocyte biology 20080901 |
Endothelin-1 regulates cardiac L-type calcium channels via NAD(P)H oxidase-derived superoxide. | The Journal of pharmacology and experimental therapeutics 20080901 |
Aldosterone induces interleukin-18 through endothelin-1, angiotensin II, Rho/Rho-kinase, and PPARs in cardiomyocytes. | American journal of physiology. Heart and circulatory physiology 20080901 |
The role of endothelin pathway in modulation of airway reactivity to methacholine in C57Bl/6 and BALB/c mice. | European journal of pharmacology 20080820 |
ADP-ribosyl cyclase and ryanodine receptors mediate endothelin ETA and ETB receptor-induced renal vasoconstriction in vivo. | American journal of physiology. Renal physiology 20080801 |
Antagonism of endothelin-1 inhibits hypoxia-induced apoptosis in cardiomyocytes. | Canadian journal of physiology and pharmacology 20080801 |
Chronic ethanol intake modulates vascular levels of endothelin-1 receptor and enhances the pressor response to endothelin-1 in anaesthetized rats. | British journal of pharmacology 20080701 |
Effect of chronic and selective endothelin receptor antagonism on microvascular function in type 2 diabetes. | American journal of physiology. Heart and circulatory physiology 20080601 |
Endothelin receptor blockers protect against ischemia/reperfusion impairment of gastrointestinal motility in rats. | Pharmacological research 20080601 |
Role of endothelin receptors on basal and endothelin-1-stimulated lung myofibroblast proliferation. | Canadian journal of physiology and pharmacology 20080601 |
Central endothelin: effects on vasopressin and the arterial baroreflex in doxorubicin heart failure rats. | Canadian journal of physiology and pharmacology 20080601 |
Potentiation of 2-methoxyestradiol-induced cytotoxicity by blocking endothelin A receptor in prostate cancer cells. | The Prostate 20080501 |
Contractile changes of the clitoral cavernous smooth muscle in female rabbits with experimentally induced overactive bladder. | The journal of sexual medicine 20080501 |
Effects of endothelin receptor type-A and type-B antagonists on prostaglandin F2alpha-induced luteolysis of the sheep corpus luteum. | Biology of reproduction 20080401 |
Interruption of endothelin signaling modifies membrane type 1 matrix metalloproteinase activity during ischemia and reperfusion. | American journal of physiology. Heart and circulatory physiology 20080201 |
Endothelin-1 mediates hypoxia-induced inhibition of voltage-gated K+ channel expression in pulmonary arterial myocytes. | American journal of physiology. Lung cellular and molecular physiology 20080201 |
Intracellular mechanisms and receptor types for endothelin-1-induced positive and negative inotropy in mouse ventricular myocardium. | Naunyn-Schmiedeberg's archives of pharmacology 20080201 |
Expression of the hyperpolarization-activated current, I(f), in cultured adult rat ventricular cardiomyocytes and its modulation by hypertrophic factors. | Pharmacological research 20080201 |
Effects of endothelin-1 1-31 on cell viabililty and [Ca2+]i in cultured neonatal rat cardiomyocytes. | Physiological research 20080101 |
The endothelin-1 pathway and the development of cardiovascular defects in the haemodynamically challenged chicken embryo. | Journal of vascular research 20080101 |
19F NMR in vivo spectroscopy reflects the effectiveness of perfusion-enhancing vascular modifiers for improving gemcitabine chemotherapy. | Magnetic resonance in medicine 20080101 |
Endothelin-1 potentiation of coronary artery contraction after ischemia-reperfusion. | Vascular pharmacology 20080101 |
Endothelin-1 and serotonin are involved in activation of RhoA/Rho kinase signaling in the chronically hypoxic hypertensive rat pulmonary circulation. | Journal of cardiovascular pharmacology 20071201 |
Altered role of smooth muscle endothelin receptors in coronary endothelin-1 and alpha1-adrenoceptor-mediated vasoconstriction in Type 2 diabetes. | American journal of physiology. Heart and circulatory physiology 20071001 |
NADPH oxidase mediates angiotensin II-induced endothelin-1 expression in vascular adventitial fibroblasts. | Cardiovascular research 20070901 |
Involvement of inducible nitric oxide synthase in blood flow decrease in vein induced by hen-egg white lysozyme. | Biological & pharmaceutical bulletin 20070701 |
Endothelin-1 and pancreatic islet vasculature: studies in vivo and on isolated, vascularly perfused pancreatic islets. | American journal of physiology. Endocrinology and metabolism 20070601 |
Peripheral endothelin A receptor antagonism attenuates carcinoma-induced pain. | European journal of pain (London, England) 20070501 |
Endothelin-1 activates ETA receptors to cause reflex scratching in BALB/c mice. | British journal of pharmacology 20070501 |
Endogenous endothelin in human coronary vascular function: differential contribution of endothelin receptor types A and B. | Hypertension (Dallas, Tex. : 1979) 20070501 |
Sarcoplasmic-endoplasmic reticulum Ca2+-ATPase inhibition prevents endothelin A receptor antagonism in rat aorta. | American journal of physiology. Heart and circulatory physiology 20070401 |
Endothelins mediate neutrophil activation, ProMMP-9 release and endothelial cell detachment. | Inflammation 20070401 |
Mechanisms of direct peritoneal resuscitation-mediated splanchnic hyperperfusion following hemorrhagic shock. | Shock (Augusta, Ga.) 20070401 |
Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats. | Circulation research 20070330 |
Endothelin-1 induces functionally active CD40 protein via nuclear factor-kappaB in human vascular smooth muscle cells. | European journal of medical research 20070326 |
Dual endothelin receptor blockade acutely improves insulin sensitivity in obese patients with insulin resistance and coronary artery disease. | Diabetes care 20070301 |
Endothelin limits insulin action in obese/insulin-resistant humans. | Diabetes 20070301 |
Intraindividual comparison of human radial and internal thoracic arteries in vitro and the effect of preoperative calcium blocker therapy. | Fundamental & clinical pharmacology 20070201 |
Activation of endothelin-a receptors contributes to angiotensin-induced suppression of renal sensory nerve activation. | Hypertension (Dallas, Tex. : 1979) 20070101 |
Endothelin-1-mediated wave-like [Ca2+]i oscillations in intact rabbit inferior vena cava. | Journal of vascular research 20070101 |
Protection from renal ischemia reperfusion injury by an endothelin-A receptor antagonist BQ-123 in relation to nitric oxide production. | Toxicology 20061207 |
Regulation of dHAND protein expression by all-trans retinoic acid through ET-1/ETAR signaling in H9c2 cells. | Journal of cellular biochemistry 20061001 |
Myocardial dysfunction and neurohumoral activation without remodeling in left ventricle of monocrotaline-induced pulmonary hypertensive rats. | American journal of physiology. Heart and circulatory physiology 20061001 |
Impaired effect of endothelin-1 on coronary artery stiffness in type 2 diabetes. | International journal of cardiology 20060920 |
Activation of p38 MAPK is involved in endothelin-1-stimulated COX-2 expression in cultured Feline esophageal smooth muscle cells. | Molecules and cells 20060831 |
Ethanol consumption enhances endothelin-1-induced contraction in the isolated rat carotid. | The Journal of pharmacology and experimental therapeutics 20060801 |
Cerebrovascular dysfunction is an attractive target for therapy in heat stroke. | Clinical and experimental pharmacology & physiology 20060801 |
Orofacial cold hyperalgesia due to infraorbital nerve constriction injury in rats: reversal by endothelin receptor antagonists but not non-steroidal anti-inflammatory drugs. | Pain 20060701 |
Autocrine effects of endothelin on in vitro proliferation of vascular smooth muscle cells from spontaneously hypertensive and normotensive rats. | Clinical and experimental hypertension (New York, N.Y. : 1993) 20060701 |
Enzymatic pathways involved in the generation of endothelin-1(1-31) from exogenous big endothelin-1 in the rabbit aorta. | British journal of pharmacology 20060601 |
Arrhythmogenic action of endothelin-1(1-31) through conversion to endothelin-1(1-21). | Experimental biology and medicine (Maywood, N.J.) 20060601 |
Targeting the endothelin axis in human melanoma: combination of endothelin receptor antagonism and alkylating agents. | Experimental biology and medicine (Maywood, N.J.) 20060601 |
Effect of BQ-123 and nitric oxide inhibition on liver in rats after renal ischemia-reperfusion injury. | General physiology and biophysics 20060601 |
Endothelin-1, an ulcer inducer, promotes gastric ulcer healing via mobilizing gastric myofibroblasts and stimulates production of stroma-derived factors. | American journal of physiology. Gastrointestinal and liver physiology 20060501 |
Effects of antagonists for endothelin ET(A) and ET(B) receptors on coronary endothelial and myocardial function after ischemia-reperfusion in anesthetized goats. | Vascular pharmacology 20060501 |
Endothelin B receptor antagonist increases preproendothelin-1 transcription in bovine aortic endothelial cells and in vivo. | Journal of cardiovascular pharmacology 20060501 |
ETa-receptor blockade, but not ACE inhibition, blunts retinal vessel response during isometric exercise. | American journal of physiology. Heart and circulatory physiology 20060401 |
Increased vascular angiotensin II binding capacity and ET-1 release in young cardiomyopathic hamsters. | Vascular pharmacology 20060401 |
Contribution of endothelin receptors and cyclooxygenase-derivatives to the altered response of the rabbit renal artery to endothelin-1 in diabetes. | European journal of pharmacology 20060318 |
Effect of age on insulin-induced endothelin release and vasoreactivity in hypertriglyceridemic and hypertensive rats. | Experimental gerontology 20060301 |
Enhanced endothelium-dependent vasodilatation by dual endothelin receptor blockade in individuals with insulin resistance. | Journal of cardiovascular pharmacology 20060301 |
Difference in the characteristics of ETA-receptor-stimulated response between rat small pulmonary and renal arteries. | Journal of cardiovascular pharmacology 20060301 |
Selective endothelin a (ETA) receptor antagonist (BQ-123) reduces both myocardial infarct size and oxidant injury. | Toxicology 20060215 |
Pulmonary perfusion during lipopolysaccharide (LPS) induced fetal endotoxemia in the preterm fetal sheep. | European journal of obstetrics, gynecology, and reproductive biology 20060201 |
Positive inter-regulation between beta-catenin/T cell factor-4 signaling and endothelin-1 signaling potentiates proliferation and survival of prostate cancer cells. | Molecular pharmacology 20060201 |
Leptin regulates cardiomyocyte contractile function through endothelin-1 receptor-NADPH oxidase pathway. | Hypertension (Dallas, Tex. : 1979) 20060201 |
Involvement of endothelium and endothelin-1 in lead-induced smooth muscle cell dysfunction in rats. | Kidney international 20060201 |
Pharmacological properties of endothelin-1 in the rabbit corpus cavernosum. | In vivo (Athens, Greece) 20060101 |
Endothelin(B) receptor blocker inhibits high glucose-induced synthesis of fibronectin in human peritoneal mesothelial cells. | Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20060101 |
Effects of endothelin receptor blockade on hypervasoreactivity in streptozotocin-diabetic rats: vessel-specific involvement of thromboxane A2. | Canadian journal of physiology and pharmacology 20060101 |
Morphine tolerance does not develop in mice treated with endothelin-A receptor antagonists. | Brain research 20051207 |
Endothelin-1 enhances glutamate-induced retinal cell death, possibly through ETA receptors. | Investigative ophthalmology & visual science 20051201 |
Blood pressure responses of endothelin-1 1-31 within the rostral ventrolateral medulla through conversion to endothelin-1 1-21. | Journal of cardiovascular pharmacology 20051201 |
Inhibition of angiotensin II- and endothelin-1-stimulated proliferation by selective MEK inhibitor in cultured rabbit gingival fibroblastsdagger. | Fundamental & clinical pharmacology 20051201 |
Endothelin-1 receptor antagonist BQ123 prevents pulmonary artery hypertension induced by low ambient temperature in broilers. | Biological & pharmaceutical bulletin 20051201 |
Endothelins: pathophysiology and treatment implications in chronic heart failure. | Current heart failure reports 20051201 |
Pathways of glomerular toxicity of cyclosporine-A: an 'in vitro' study. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20051201 |
Enhanced response of pig coronary arteries to endothelin-1 after ischemia-reperfusion. Role of endothelin receptors, nitric oxide and prostanoids. | European journal of pharmacology 20051107 |
Effect of chymase on intraocular pressure in rabbits. | European journal of pharmacology 20051107 |
Nociceptive effect of subcutaneously injected interleukin-12 is mediated by endothelin (ET) acting on ETB receptors in rats. | The Journal of pharmacology and experimental therapeutics 20051101 |
Endothelin-1-mediated increase in reactive oxygen species and NADPH Oxidase activity in hearts of aryl hydrocarbon receptor (AhR) null mice. | Toxicological sciences : an official journal of the Society of Toxicology 20051101 |
Functional characterization and expression of endothelin receptors in rat carotid artery: involvement of nitric oxide, a vasodilator prostanoid and the opening of K+ channels in ETB-induced relaxation. | British journal of pharmacology 20051101 |
Glibenclamide reveals role for endothelin in hypoxia-induced vasoconstriction in rat intrapulmonary arteries. | Journal of cardiovascular pharmacology 20051001 |
[Effects of airway epithelium injury on the transdifferentiation of sub-epithelial fibroblasts and its role in the development of airway hyperresponsiveness in asthma]. | Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20051001 |
Modulation of the myocardial effects of selective ETB receptor stimulation and its implications for heart failure. | Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20050901 |
Systemic endothelial dysfunction in adults with cyanotic congenital heart disease. | Circulation 20050823 |
Endothelin-1-induced translocation of RhoA is mediated by endothelin ET(A) receptors in rat bronchial smooth muscle. | European journal of pharmacology 20050711 |
Nitric oxide inhibition unmasks ischemic myocardium-derived vasoconstrictor signals activating endothelin type A receptor of coronary microvessels. | American journal of physiology. Heart and circulatory physiology 20050701 |
Endothelin isoforms and the response to myocardial stretch. | American journal of physiology. Heart and circulatory physiology 20050601 |
The genomic response to retinal disease and injury: evidence for endothelin signaling from photoreceptors to glia. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050504 |
Gender differences in small intestinal perfusion following trauma hemorrhage: the role of endothelin-1. | American journal of physiology. Gastrointestinal and liver physiology 20050501 |
Exaggerated coronary vasoreactivity to endothelin-1 in aged rats: role of protein kinase C. | Cardiovascular research 20050501 |
Cyclo-oxygenase-2, endothelium and aortic reactivity during deoxycorticosterone acetate salt-induced hypertension. | Journal of hypertension 20050501 |
Endothelin receptors in lower esophageal sphincter circular smooth muscle. | Regulatory peptides 20050415 |
[H]BQ-123 binding to native endothelin ET(A) receptors in human astrocytoma 1321N1 cells and screening of potential ligands. | Pharmacology 20050401 |
Endothelin 1 versus endothelin 3 in the development of the slow force response to myocardial stretch. | The Canadian journal of cardiology 20050401 |
Cardiovascular effects and lethality of venom from nematocysts of the box-jellyfish Chiropsalmus quadrigatus (Habu-kurage) in anaesthetized rats. | Toxicon : official journal of the International Society on Toxinology 20050315 |
Endothelin mediates superoxide production in angiotensin II-induced hypertension in rats. | Free radical biology & medicine 20050301 |
Endothelin receptor blockade improves endothelial function in atherosclerotic patients on angiotensin converting enzyme inhibition. | Journal of internal medicine 20050301 |
Delphinidin-3-rutinoside relaxes the bovine ciliary smooth muscle through activation of ETB receptor and NO/cGMP pathway. | Experimental eye research 20050301 |
Insulin and endothelin in the acute regulation of adiponectin in vivo in humans. | Obesity research 20050301 |
Chronic endothelin exposure inhibits connexin43 expression in cultured cortical astroglia. | Journal of neuroscience research 20050201 |
Intercellular communication via gap junctions in activated rat hepatic stellate cells. | Gastroenterology 20050201 |
[Changes of activity of the endothelial system in experimental heart failure]. | Kardiologiia 20050101 |
Mast cells promote homeostasis by limiting endothelin-1-induced toxicity. | Nature 20041125 |
Mechanisms underlying enhanced contractile response to endothelin-1 in diabetic rat basilar artery. | Peptides 20041101 |
A novel combination of opiates and endothelin antagonists to manage pain without any tolerance development. | Journal of cardiovascular pharmacology 20041101 |
Endothelin-1 stimulates cyclooxygenase-2 expression in ovarian cancer cells through multiple signaling pathways: evidence for involvement of transactivation of the epidermal growth factor receptor. | Journal of cardiovascular pharmacology 20041101 |
The impact of respiratory syncytial virus infection on endothelin receptor function and release in sheep bronchial explants. | Journal of cardiovascular pharmacology 20041101 |
Synergistic stimulation of aldosterone production in human adrenocortical carcinoma NCI-H295R cells by endothelin-1 and angiotensin II. | Journal of cardiovascular pharmacology 20041101 |
Inhibitory actions of endothelin-1 on pain processing. | Journal of cardiovascular pharmacology 20041101 |
Pharmacological characterization of YM598, a selective endothelin-A receptor antagonist. | Journal of cardiovascular pharmacology 20041101 |
The effect of cerivastatin therapy on vascular responses to endothelin antagonists in humans. | Journal of cardiovascular pharmacology 20041101 |
Endothelins induce ETB receptor-mediated mechanical hypernociception in rat hindpaw: roles of cAMP and protein kinase C. | European journal of pharmacology 20041006 |
Endothelin-B-receptor-selective antagonist inhibits endothelin-1 induced potentiation on the vasoconstriction to noradrenaline and angiotensin II. | Journal of hypertension 20041001 |
Endothelin ETB receptor signaling in the median eminence and subfornical organ of the rat brain. | Neuropeptides 20041001 |
Endothelin A receptor antagonism and angiotensin-converting enzyme inhibition are synergistic via an endothelin B receptor-mediated and nitric oxide-dependent mechanism. | Journal of the American Society of Nephrology : JASN 20041001 |
Prior antagonism of endothelin-1A receptors alleviates circulatory shock and cerebral ischemia during rat heatstroke. | Journal of pharmacological sciences 20041001 |
Association of endothelin with lung hemorrhage induced by immune complexes in rats. | Inflammation 20041001 |
Superiority of YM598 over atrasentan as a selective endothelin ETA receptor antagonist. | European journal of pharmacology 20040913 |
Prediction of in vivo biliary clearance from the in vitro transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II monolayer expressing both rat organic anion transporting polypeptide 4 and multidrug resistance associated protein 2. | Molecular pharmacology 20040901 |
Endothelin upregulates the expression of vasopressin V2 mRNA in the inner medullary collecting duct of the rat. | Metabolism: clinical and experimental 20040901 |
Endothelin-1-mediated coronary vasoconstriction deteriorates myocardial depression in hearts isolated from lipopolysaccharide-treated rats: interaction with nitric oxide. | Clinical and experimental pharmacology & physiology 20040901 |
[Endothelin-1 and arteriosclerosis]. | Nihon rinsho. Japanese journal of clinical medicine 20040901 |
[Prospects for endothelin-related drugs]. | Nihon rinsho. Japanese journal of clinical medicine 20040901 |
Endothelin-1-induced responses in isolated mouse vessels: the expression and function of receptor types. | American journal of physiology. Heart and circulatory physiology 20040801 |
Interleukin-18 induces mechanical hypernociception in rats via endothelin acting on ETB receptors in a morphine-sensitive manner. | The Journal of pharmacology and experimental therapeutics 20040801 |
Proliferative response to phenytoin and nifedipine in gingival fibroblasts cultured from humans with gingival fibromatosis. | Fundamental & clinical pharmacology 20040801 |
Obligatory role for endogenous endothelin in mediating the hypertrophic effects of phenylephrine and angiotensin II in neonatal rat ventricular myocytes: evidence for two distinct mechanisms for endothelin regulation. | The Journal of pharmacology and experimental therapeutics 20040701 |
Endothelins and their inhibition in the human skin microcirculation: ET[1-31], a new vasoconstrictor peptide. | British journal of clinical pharmacology 20040601 |
Endothelin-induced constriction of the ductus venosus in fetal sheep: developmental aspects and possible interaction with vasodilatory prostaglandin. | British journal of pharmacology 20040601 |
[Endothelin]. | Nihon rinsho. Japanese journal of clinical medicine 20040601 |
Dual effects of endothelin-1 (1-31): induction of mesangial cell migration and facilitation of monocyte recruitment through monocyte chemoattractant protein-1 production by mesangial cells. | Hypertension research : official journal of the Japanese Society of Hypertension 20040601 |
Ventricular nonmyocytes inhibit doxorubicin-induced myocyte apoptosis: involvement of endogenous endothelin-1 as a paracrine factor. | Endocrinology 20040501 |
ET-1 induces cortical spreading depression via activation of the ETA receptor/phospholipase C pathway in vivo. | American journal of physiology. Heart and circulatory physiology 20040401 |
Regulation of vasopressin secretion by ETA and ETB receptors in compartmentalized rat hypothalamo-neurohypophysial explants. | American journal of physiology. Endocrinology and metabolism 20040401 |
Effects of endothelin-1 on portal-systemic collaterals of common bile duct-ligated cirrhotic rats. | European journal of clinical investigation 20040401 |
Implantation of tumoral XC cells induces chronic, endothelin-dependent, thermal hyperalgesia in mice. | Cellular and molecular neurobiology 20040401 |
Endothelin causes contraction of human esophageal muscularis mucosae through interaction with both ETA and ETB receptors. | Regulatory peptides 20040315 |
Mechanisms underlying diabetes enhancement of endothelin-1-induced contraction in rabbit basilar artery. | European journal of pharmacology 20040223 |
Different role of endothelin ETA and ETB receptors and endothelial modulators in diabetes-induced hyperreactivity of the rabbit carotid artery to endothelin-1. | European journal of pharmacology 20040213 |
The role of endothelin in mediating ischemia/hypoxia-induced atrial natriuretic peptide release. | Journal of cardiovascular pharmacology 20040201 |
Endothelins contribute towards nociception induced by antigen in ovalbumin-sensitised mice. | British journal of pharmacology 20040201 |
Role of oxidative stress and nitric oxide in regulation of spontaneous tone in aorta of DOCA-salt hypertensive rats. | British journal of pharmacology 20040201 |
Inward current oscillation underlying tonic contraction caused via ETA receptors in pig detrusor smooth muscle. | American journal of physiology. Renal physiology 20040101 |
In-vivo interaction of nitric oxide and endothelin. | Journal of hypertension 20040101 |
Profibrotic effects of endothelin-1 via the ETA receptor in cultured human cardiac fibroblasts. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20040101 |
Angiotensin II signaling pathways mediate expression of cardiac T-type calcium channels. | Circulation research 20031212 |
Endothelin receptor blockade has an oxygen-saving effect in Dahl salt-sensitive rats with heart failure. | American journal of physiology. Heart and circulatory physiology 20031001 |
Endothelin-A receptors mediate renal hemodynamic effects of exogenous Angiotensin II in humans. | Hypertension (Dallas, Tex. : 1979) 20031001 |
[Involvement of endothelin in the proliferative effect of lysophosphatidic acid on vascular smooth muscle cells in rats]. | Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20031001 |
Cerebral angiogenesis and expression of VEGF after subarachnoid hemorrhage (SAH) in rats. | Brain research 20030815 |
Reduction of nitrite production by endothelin-1 in isolated porcine ciliary processes. | Experimental eye research 20030801 |
Endothelin receptor blockade inhibits molecular effectors of Kaposi's sarcoma cell invasion and tumor growth in vivo. | The American journal of pathology 20030801 |
Actions of endothelin and corticotropin releasing factor in the guinea-pig ileum: no evidence for an interaction with capsaicin-sensitive neurons. | Neuropeptides 20030801 |
Endothelin-1 is a potent regulator in vivo in vascular calcification and in vitro in calcification of vascular smooth muscle cells. | Peptides 20030801 |
Dual role of endothelin-1 via ETA and ETB receptors in regulation of cardiac contractile function in mice. | American journal of physiology. Heart and circulatory physiology 20030701 |
Endothelin-1 and vascular tone in subjects with atherogenic risk factors. | Hypertension (Dallas, Tex. : 1979) 20030701 |
Endothelin-1 inhibits TNF alpha-induced iNOS expression in 3T3-F442A adipocytes. | British journal of pharmacology 20030701 |
Thrombin inhibits NMDA-mediated nociceptive activity in the mouse: possible mediation by endothelin. | The Journal of physiology 20030615 |
Hemodynamic and proinflammatory actions of endothelin-1 in guinea pig small intestine submucosal microcirculation. | American journal of physiology. Gastrointestinal and liver physiology 20030601 |
Role of endothelin ETA and ETB receptors in the guinea-pig urinary bladder contraction. | European journal of pharmacology 20030530 |
Endothelin ET(A) but not ET(B) receptors mediate contraction of common bile duct. | Regulatory peptides 20030515 |
Antiapoptotic effect of endothelin-1 in rat cardiomyocytes in vitro. | Hypertension (Dallas, Tex. : 1979) 20030501 |
Regulation of human retinal blood flow by endothelin-1. | Experimental eye research 20030501 |
Developmental changes in the functional, biochemical and molecular properties of rat bladder endothelin receptors. | Naunyn-Schmiedeberg's archives of pharmacology 20030501 |
Pharmacological characterization of TA-0201, an endothelin receptor antagonist, with recombinant and human prostate endothelin receptors. | European journal of pharmacology 20030425 |
Endothelin receptor antagonists restore morphine analgesia in morphine tolerant rats. | Peptides 20030401 |
Binding of a new bioactive 31-amino-acid endothelin-1 to an endothelin ET(B) or ET(B)-like receptor in porcine lungs. | European journal of pharmacology 20030328 |
Will endothelin receptor antagonists have a role in heart failure? | The Medical clinics of North America 20030301 |
Endothelin-1 stimulated capacitative Ca2+ entry through ET(A) receptors of a rat brain-derived type-1 astrocyte cell line, IA-1g1. | Cellular signalling 20030201 |
Role of endothelin-1 in choroidal blood flow regulation during isometric exercise in healthy humans. | Investigative ophthalmology & visual science 20030201 |
Effect of endothelin-1 (1-31) on the renal resistance vessels. | The journal of medical investigation : JMI 20030201 |
ETA, mixed ETA/ETB receptor antagonists, and protein kinase C inhibitor prevent acute hypoxic pulmonary vasoconstriction: influence of potassium channels. | Journal of cardiovascular pharmacology 20030101 |
Endothelin receptor blockade lowers plasma aldosterone levels via different mechanisms in primary aldosteronism and high-to-normal renin hypertension. | Cardiovascular research 20030101 |
Role of K+ATP channels, endothelin A receptors, and effect of angiotensin II on blood flow in oral tissues. | Journal of dental research 20030101 |
Et-A receptor antagonist BQ123 prevents radiocontrast media-induced renal medullary hypoxia. | Acta radiologica (Stockholm, Sweden : 1987) 20030101 |
Endothelin ET A- and ET B-receptor-mediated inhibition of noradrenaline release from isolated rat stomach. | Journal of pharmacological sciences 20030101 |
Endothelin-1 increases calcium and attenuates renin gene expression in As4.1 cells. | American journal of physiology. Heart and circulatory physiology 20021201 |
Insulin sensitivity and big ET-1 conversion to ET-1 after ETA- or ETB-receptor blockade in humans. | Journal of applied physiology (Bethesda, Md. : 1985) 20021201 |
Endothelin-1-induced vasospasms of spiral modiolar artery are mediated by rho-kinase-induced Ca(2+) sensitization of contractile apparatus and reversed by calcitonin gene-related Peptide. | Stroke 20021201 |
Mechanisms of peripheral microvascular dysfunction in transgenic mice overexpressing the Alzheimer's disease amyloid Abeta protein. | Journal of Alzheimer's disease : JAD 20021201 |
Role of endothelin type B receptor in NO/cGMP signaling pathway in rat median eminence. | Cellular and molecular neurobiology 20021201 |
Mechanism of endothelin-1-induced cytosolic Ca(2+) mobility in cultured H9c2 myocardiac ventricular cells. | Cellular signalling 20021001 |
Endothelin-induced modulation of neuropeptide Y and norepinephrine release from the rat mesenteric bed. | American journal of physiology. Heart and circulatory physiology 20021001 |
Increased activity of endogenous endothelin in patients with type II diabetes mellitus. | Circulation 20021001 |
Different contractile effects of alpha1- and alpha2-adrenergic agonists on horse isolated common digital artery smooth muscle ring preparations in vitro. | Pharmacological research 20021001 |
Potentiation of morphine analgesia by BQ123, an endothelin antagonist. | Peptides 20021001 |
The vascular endothelin system is not overactive in normotensive hemodialysis patients. | Kidney international 20020901 |
Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors. | European journal of immunology 20020901 |
Involvement of endothelin-1 and its receptors in PGF2alpha-induced luteolysis in the rat. | Molecular reproduction and development 20020901 |
Inhibitory activity on binding of specific ligands to the human angiotensin II AT(1) and endothelin 1 ET(A) receptors: bioactive benzo[c]phenanthridine alkaloids from the root of Bocconia frutescens. | Planta medica 20020901 |
Possible mechanism of endothelin-induced Ca2+ mobility in A7r5 cultured vascular smooth muscle cells. | The Kaohsiung journal of medical sciences 20020901 |
Enhanced vasoconstriction to endothelin-1, angiotensin II and noradrenaline in carriers of the GNB3 825T allele in the skin microcirculation. | Pharmacogenetics 20020801 |
Forearm vasoconstriction to endothelin-1 is impaired, but constriction to sarafotoxin 6c and vasodilatation to BQ-123 unaltered, in patients with essential hypertension. | Clinical science (London, England : 1979) 20020801 |
Endothelin-1 (1-31) induces a thiorphan-sensitive release of eicosanoids via ET(B) receptors in the guinea pig perfused lung. | Clinical science (London, England : 1979) 20020801 |
Modulation of ET(B) receptor-induced arginine-vasopressin secretion by N-methyl-D-aspartate (NMDA) and gamma-aminobutyric acid (GABA)-dependent mechanisms in hypothalamo-neurohypophysial explants. | Clinical science (London, England : 1979) 20020801 |
Differential vasoactive response to endothelin receptor antagonists and prostacyclin in patients with severe pulmonary hypertension. | Clinical science (London, England : 1979) 20020801 |
Impact of parainfluenza-3 virus infection on endothelin receptor density and function in guinea pig airways. | Clinical science (London, England : 1979) 20020801 |
Role of endothelin receptors in the hypertensive state of kinin B(2) knockout mice subjected to a high-salt diet. | Clinical science (London, England : 1979) 20020801 |
Reduction of endothelin-1 binding and inhibition of endothelin-1-mediated detrusor contraction by naftidrofuryl. | Clinical science (London, England : 1979) 20020801 |
Altered mitogen-activated protein kinase activation in vascular smooth muscle cells from spontaneously hypertensive rats. | Clinical and experimental pharmacology & physiology 20020701 |
Mental stress induces prolonged endothelial dysfunction via endothelin-A receptors. | Circulation 20020618 |
International Union of Pharmacology. XXIX. Update on endothelin receptor nomenclature. | Pharmacological reviews 20020601 |
Action of the endothelin receptor (ETA) antagonist BQ-123 on forearm blood flow in young normotensive subjects. | Clinical science (London, England : 1979) 20020601 |
Hyperglycemia exaggerates ischemia-reperfusion-induced cardiomyocyte injury: reversal with endothelin antagonism. | The Journal of thoracic and cardiovascular surgery 20020601 |
Pronatriuretic peptide is a sensitive marker of the endocrine function of teleost heart. | American journal of physiology. Endocrinology and metabolism 20020401 |
Endothelin ETA receptor-subtype specific antagonism does not mitigate the acute systemic or renal effects of exogenous angiotensin II in humans. | European journal of clinical investigation 20020401 |
Endothelin blockade potentiates endothelial protective effects of ACE inhibitors in saphenous veins. | The Annals of thoracic surgery 20020401 |
A novel bioactive 31-amino acid ET-1 peptide stimulates eosinophil recruitment and increases the levels of eotaxin and IL-5. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020401 |
Endothelin-1 binding to endothelin receptors in the rat anterior pituitary gland: possible formation of an ETA-ETB receptor heterodimer. | Cellular and molecular neurobiology 20020401 |
Endothelin-A receptors and NO mediate decrease in arterial pressure during recovery from restraint. | American journal of physiology. Regulatory, integrative and comparative physiology 20020301 |
Endothelin-1 inhibits endothelium-dependent vasodilatation in the human forearm: reversal by ETA receptor blockade in patients with atherosclerosis. | Clinical science (London, England : 1979) 20020301 |
Stimulation of catecholamine biosynthesis via the protein kinase C pathway by endothelin-1 in PC12 rat pheochromocytoma cells. | Biochemical pharmacology 20020301 |
Endothelin-3 induces both human and opossum gallbladder contraction mediated mainly by endothelin-B receptor subtype in vitro. | Journal of gastroenterology and hepatology 20020301 |
Endothelial modulation of skeletal muscle blood flow and VO(2) during low- and high-intensity contractions. | Journal of applied physiology (Bethesda, Md. : 1985) 20020201 |
Improved endothelium-dependent vasodilation after blockade of endothelin receptors in patients with essential hypertension. | Circulation 20020129 |
Endothelin in the mechanism of endothelial injury and neutrophil adhesion in the post-ischemic guinea-pig heart. | European journal of pharmacology 20020102 |
Endothelin-1[1-31]: a novel autocrine-paracrine regulator of human adrenal cortex secretion and growth. | The Journal of clinical endocrinology and metabolism 20020101 |
Endothelin-1 activates ET(A) receptors to increase intracellular calcium in model sensory neurons. | Neuroreport 20011204 |
Coronary vasodilation and improvement in endothelial dysfunction with endothelin ET(A) receptor blockade. | Circulation research 20011123 |
Myocardial contractile responsiveness to endothelin-1 in the post-infarction rat model of heart failure: effects of chronic quinapril. | Journal of molecular and cellular cardiology 20011101 |
Rationale and perspective of endothelin-1 antagonism in acute heart failure. | Journal of cardiovascular pharmacology 20011101 |
Autocrine regulation of prolactin secretion by endothelins: a permissive role for estradiol. | Endocrine 20011101 |
Endothelin-1 induces contraction of human and Australian possum gallbladder in vitro. | Regulatory peptides 20011015 |
Endothelin receptor blockade and nitric oxide bioactivity. | Cardiovascular research 20011001 |
[Down-regulation of ETA receptor of vascular smooth muscle cells by 17 beta-estradiol]. | Sheng li xue bao : [Acta physiologica Sinica] 20011001 |
Role of endothelin-1 in the active constriction of human atherosclerotic coronary arteries. | Circulation 20010904 |
Endothelin-A receptor antagonist inhibits angiotensin II and noradrenaline in man. | British journal of clinical pharmacology 20010801 |
Differential desensitization of Ca2+ mobilization and vasoconstriction by ET(A) receptors in the gerbil spiral modiolar artery. | The Journal of membrane biology 20010801 |
Endothelin mediates some of the renal actions of acutely administered angiotensin II. | Hypertension (Dallas, Tex. : 1979) 20010701 |
Factors involved in the time course of response to acetylcholine in mesenteric arteries from spontaneously hypertensive rats. | European journal of pharmacology 20010629 |
Endothelin-1 mediates prostaglandin F(2alpha)-induced luteal regression in the ewe. | Biology of reproduction 20010601 |
Endothelium-dependent relaxation in response to low concentrations of bradykinin is enhanced by phosphoramidon, bosentan and BQ-123 in bovine coronary arteries in vitro. | Japanese journal of pharmacology 20010601 |
Paradoxically enhanced endothelin-B receptor-mediated vasoconstriction in conscious old monkeys. | Circulation 20010515 |
Functional and biochemical evidence for capsaicin-induced neural endothelin release in isolated working rat heart. | European journal of pharmacology 20010511 |
A novel pharmacological action of ET-1 to prevent the cytotoxicity of doxorubicin in cardiomyocytes. | American journal of physiology. Regulatory, integrative and comparative physiology 20010501 |
Caged and clustered structures of endothelin inhibitor BQ123, cyclo(-D-Trp-D-Asp--Pro-D-Val-Leu-)-Na+, forming five and six coordination bonds between sodium ions and peptides. | Acta crystallographica. Section D, Biological crystallography 20010501 |
The polycationic aminoglycosides modulate the vasoconstrictive effects of endothelin: relevance to cerebral vasospasm. | British journal of pharmacology 20010501 |
Endothelin receptor antagonists in congestive heart failure: a new therapeutic principle for the future? | Journal of the American College of Cardiology 20010501 |
Pulmonary adrenomedullin counteracts deterioration of coronary flow and myocardial performance evoked by pulmonary endothelins in experimental acute respiratory distress syndrome. | Critical care medicine 20010501 |
Endothelin receptors in human and guinea-pig gallbladder muscle. | Regulatory peptides 20010420 |
Intravasal peroxynitrite generation causes dysfunction in the isolated perfused rat lung via endothelin. | The Journal of pharmacology and experimental therapeutics 20010401 |
Endothelin-1 induces vasoconstriction on portal-systemic collaterals of portal hypertensive rats. | Hepatology (Baltimore, Md.) 20010401 |
Effect of the blood substitute diaspirin crosslinked hemoglobin in rat mesenteric and human radial collateral arteries. | Journal of cardiovascular pharmacology 20010401 |
Effects of endothelin-1 and nitric oxide on proliferation of cultured guinea pig bronchial smooth muscle cells. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010401 |
Signaling pathways involved in the A and B receptor-mediated cortisol secretagogue effect of endothelins in the human adrenal cortex. | International journal of molecular medicine 20010301 |
Endothelin receptor blockade inhibits proliferation of Kaposi's sarcoma cells. | The American journal of pathology 20010301 |
Inositolphosphate formation in thoracic and abdominal rat aorta following Gq/11-coupled receptor stimulation. | Naunyn-Schmiedeberg's archives of pharmacology 20010301 |
Augmentation of endothelial function by endothelin antagonism in human saphenous vein conduits. | Journal of neurosurgery 20010201 |
Endothelin antagonism uncovers insulin-mediated vasorelaxation in vitro and in vivo. | Hypertension (Dallas, Tex. : 1979) 20010201 |
Design, syntheses, and structure-activity relationships of indan derivatives as endothelin antagonists; new lead generation of non-peptidic antagonist from peptidic leads. | Bioorganic & medicinal chemistry 20010201 |
Mitogen-activated protein kinase activity regulation role of angiotensin and endothelin systems in vascular smooth muscle cells. | European journal of pharmacology 20010105 |
Endothelin receptor blockade improves endothelial function in human internal mammary arteries. | Cardiovascular research 20010101 |
A N-terminal PTHrP peptide fragment void of a PTH/PTHrP-receptor binding domain activates cardiac ET(A) receptors. | British journal of pharmacology 20010101 |
Contribution of angiotensin II, endothelin 1 and the endothelium to the slow inotropic response to stretch in ferret papillary muscle. | Pflugers Archiv : European journal of physiology 20010101 |
Bone blood flow and vascular reactivity. | Cells, tissues, organs 20010101 |
Allosteric inhibition of endothelin ETA receptors by 3, 5-dibromosalicylic acid. | Molecular pharmacology 20001201 |
Location of alkali metal binding sites in endothelin A selective receptor antagonists, cyclo(D-Trp-D-Asp-Pro-D-Val-Leu) and cyclo(D-Trp-D-Asp-Pro-D-Ile-Leu), from multistep collisionally activated decompositions. | Journal of mass spectrometry : JMS 20000201 |
Angiotensin II receptor blockade unmasks a depressor response to endothelin antagonists in rats. | Fundamental & clinical pharmacology 20000101 |
Suc-[Glu9,Ala11,15]-endothelin-1 (8-21), IRL 1620, identifies two populations of ET(B) receptors in guinea-pig bronchus. | British journal of pharmacology 19990701 |
Novel sodium binding properties of some cyclopentapeptide endothelin A selective receptor antagonists: electrospray and fast-atom-bombardment mass spectrometric studies. | Biochemical and biophysical research communications 19990127 |
Altered inotropic response of endothelin-1 in cardiomyocytes from rats with isoproterenol-induced cardiomyopathy. | Cardiovascular research 19980901 |
Role of endothelin in the human craniofacial morphogenesis. | Journal of craniofacial genetics and developmental biology 19980101 |
Endothelin receptor-mediated Ca2+ mobilization and contraction in bovine oviductal arteries: comparison with noradrenaline and potassium. | General pharmacology 19971001 |
Endothelin ETA receptors subtype mediates phosphoinositide hydrolysis in adrenal medulla. | Archives of physiology and biochemistry 19970901 |
Excitatory gastric motor and cardiovascular effects of endothelins in the dorsal vagal complex are mediated through ET(A) receptors. | The Journal of pharmacology and experimental therapeutics 19970801 |
Rediscovering an endothelin antagonist (BQ-123): a self-deconvoluting cyclic pentapeptide library. | Journal of medicinal chemistry 19960913 |
Endothelin-1 stimulates deoxyribonucleic acid synthesis and contraction in testicular peritubular myoid cells. | Biology of reproduction 19960301 |
Endothelin-1 inhibits L-type Ca currents enhanced by isoproterenol in guinea-pig ventricular myocytes. | Pflugers Archiv : European journal of physiology 19960201 |
Endothelin-induced nociception in mice: mediation by ETA and ETB receptors. | The Journal of pharmacology and experimental therapeutics 19960201 |
Role of endothelin in the cardiovascular effects of diaspirin crosslinked and stroma reduced hemoglobin. | Critical care medicine 19960101 |
The effect of endothelin-2 (ET-2) on migration and changes in cytosolic free calcium of neutrophils. | Naunyn-Schmiedeberg's archives of pharmacology 19960101 |
Endothelin acts as a paracrine regulator of stretch-induced atrial natriuretic peptide release. | The American journal of physiology 19951101 |
Structure-activity relationships of cyclic pentapeptide endothelin A receptor antagonists. | Journal of medicinal chemistry 19951013 |
[Demonstration of a vasopressor role of endogenous endothelin after inhibition of nitric oxide synthesis in rats]. | Archives des maladies du coeur et des vaisseaux 19950801 |
ETA receptor-mediated constrictor responses to endothelin peptides in human blood vessels in vitro. | British journal of pharmacology 19950501 |
Nonpeptide endothelin receptor antagonists: IV. Identification of receptors in rabbit colonic mucosa and smooth muscle and correlation with physiological effects. | The Journal of pharmacology and experimental therapeutics 19950301 |
[3H]BQ-123, a highly specific and reversible radioligand for the endothelin ETA receptor subtype. | European journal of pharmacology 19950214 |
In vivo evidence of an endothelin-induced vasopressor tone after inhibition of nitric oxide synthesis in rats. | Circulation 19950201 |
Characterization of endothelin-1-induced vascular effects in the rat heart by using endothelin receptor antagonists. | European journal of pharmacology 19941212 |
Solvent effects on the conformation of cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu-). An NMR spectroscopy and molecular modeling study. | International journal of peptide and protein research 19940501 |
Mutational analysis of human endothelin receptors ETA and ETB identification of regions involved in the selectivity for endothelin 3 or cyclo-(D-Trp-D-Asp-Pro-D-Val-Leu). | European journal of biochemistry 19940501 |
Differential blockade of the renal vasoconstrictor and diuretic responses to endothelin-1 by endothelin antagonist. | Clinical and experimental pharmacology & physiology 19940401 |
Characterization of iris sphincter smooth muscle endothelin receptor subtypes which are coupled to cyclic AMP formation and polyphosphoinositide hydrolysis. | The Journal of pharmacology and experimental therapeutics 19940301 |
[125I]-PD151242: a selective radioligand for human ETA receptors. | British journal of pharmacology 19940101 |
Reversal of subarachnoid hemorrhage-induced vasoconstriction with an endothelin receptor antagonist. | Neurosurgery 19940101 |
A conformational study by 1H NMR of a cyclic pentapeptide antagonist of endothelin. | Journal of medicinal chemistry 19930903 |
Receptor externalization determines sustained contractile responses to endothelin-1 in the rat aorta. | The American journal of physiology 19930301 |
BQ-123, cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu), is a non-competitive antagonist of the actions of endothelin-1 in SK-N-MC human neuroblastoma cells. | Biochemical and biophysical research communications 19920415 |
Solution conformation of a cyclic pentapeptide endothelin antagonist. Comparison of structures obtained from constrained dynamics and conformational search. | FEBS letters 19920316 |
Conformational study of cyclo[D-Trp-D-Asp-Pro-D-Val-Leu], an endothelin-A receptor-selective antagonist. | FEBS letters 19920113 |