THIOFLAVINE S
| Title | Journal |
|---|---|
| Hopeahainol A binds reversibly at the acetylcholinesterase (AChE) peripheral site and inhibits enzyme activity with a novel higher order concentration dependence. | Chemico-biological interactions 20161125 |
| Inhibition of human islet amyloid polypeptide or amylin aggregation by two manganese-salen derivatives. | European journal of pharmacology 20130505 |
| Surface chemistry at the nanometer scale influences insulin aggregation. | Colloids and surfaces. B, Biointerfaces 20121201 |
| Unzipping the role of chirality in nanoscale self-assembly of tripeptide hydrogels. | Nanoscale 20121107 |
| Influence of the valine zipper region on the structure and aggregation of the basic leucine zipper (bZIP) domain of activating transcription factor 5 (ATF5). | Molecular pharmaceutics 20121105 |
| The N-methylated peptide SEN304 powerfully inhibits Aβ(1-42) toxicity by perturbing oligomer formation. | Biochemistry 20121023 |
| The butter flavorant, diacetyl, exacerbates β-amyloid cytotoxicity. | Chemical research in toxicology 20121015 |
| Molecular rotors: what lies behind the high sensitivity of the thioflavin-T fluorescent marker. | Accounts of chemical research 20120918 |
| Effect of melatonin on α-synuclein self-assembly and cytotoxicity. | Neurobiology of aging 20120901 |
| Binding of the three-repeat domain of tau to phospholipid membranes induces an aggregated-like state of the protein. | Biochimica et biophysica acta 20120901 |
| Amyloid-like fibril formation by tachykinin neuropeptides and its relevance to amyloid β-protein aggregation and toxicity. | Cell biochemistry and biophysics 20120901 |
| Cross-seeding effects of amyloid β-protein and α-synuclein. | Journal of neurochemistry 20120901 |
| Efficient access to highly pure β-amyloid peptide by optimized solid-phase synthesis. | Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20120901 |
| Characterization of semisynthetic and naturally Nα-acetylated α-synuclein in vitro and in intact cells: implications for aggregation and cellular properties of α-synuclein. | The Journal of biological chemistry 20120817 |
| Interaction between amyloid-β pathology and cortical functional columnar organization. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120815 |
| Short polyglutamine peptide forms a high-affinity binding site for thioflavin-T at the N-terminus. | Organic & biomolecular chemistry 20120814 |
| Mutant p53 aggregates into prion-like amyloid oligomers and fibrils: implications for cancer. | The Journal of biological chemistry 20120810 |
| Inhibitory effect of curcumin on the Al(III)-induced Aβ₄₂ aggregation and neurotoxicity in vitro. | Biochimica et biophysica acta 20120801 |
| Anti-amyloidogenic effects of soybean isoflavones in vitro: Fluorescence spectroscopy demonstrating direct binding to Aβ monomers, oligomers and fibrils. | Biochimica et biophysica acta 20120801 |
| Ligand electronic properties modulate tau filament binding site density. | Biophysical chemistry 20120801 |
| PEGylated nanoparticles bind to and alter amyloid-beta peptide conformation: toward engineering of functional nanomedicines for Alzheimer's disease. | ACS nano 20120724 |
| Biocompatibility of mannan nanogel--safe interaction with plasma proteins. | Biochimica et biophysica acta 20120701 |
| Dissecting the role of disulfide bonds on the amyloid formation of insulin. | Biochemical and biophysical research communications 20120629 |
| Separation and detection of individual Aβ aggregates by capillary electrophoresis with laser-induced fluorescence detection. | Analytical biochemistry 20120615 |
| Fluorescent 2-styrylpyridazin-3(2H)-one derivatives as probes targeting amyloid-beta plaques in Alzheimer's disease. | Bioorganic & medicinal chemistry letters 20120615 |
| D-Ser-containing humanin shows promotion of fibril formation. | Amino acids 20120601 |
| Naphthoquinone-tyrptophan reduces neurotoxic Aβ*56 levels and improves cognition in Alzheimer's disease animal model. | Neurobiology of disease 20120601 |
| A new trend in the experimental methodology for the analysis of the thioflavin T binding to amyloid fibrils. | Molecular neurobiology 20120601 |
| Ultrafast molecular rotor: an efficient sensor for premelting of natural DNA. | Chemical communications (Cambridge, England) 20120528 |
| An FT-IR study on packing defects in mixed β-aggregates of poly(L-glutamic acid) and poly(D-glutamic acid): a high-pressure rescue from a kinetic trap. | The journal of physical chemistry. B 20120503 |
| Trifluoroethanol and acetonitrile induced formation of the molten globule states and aggregates of cellulase. | International journal of biological macromolecules 20120501 |
| Optimization of potent hepatitis C virus NS3 helicase inhibitors isolated from the yellow dyes thioflavine S and primuline. | Journal of medicinal chemistry 20120412 |
| Using graphene oxide high near-infrared absorbance for photothermal treatment of Alzheimer's disease. | Advanced materials (Deerfield Beach, Fla.) 20120403 |
| Modulation of pathway of insulin fibrillation by a small molecule helix inducer 2,2,2-trifluoroethanol. | Colloids and surfaces. B, Biointerfaces 20120401 |
| Molecular imaging of amyloidosis: will the heart be the next target after the brain? | Current cardiology reports 20120401 |
| Hexafluoroisopropanol induces self-assembly of β-amyloid peptides into highly ordered nanostructures. | Journal of peptide science : an official publication of the European Peptide Society 20120401 |
| Identification and characterization of an aβ oligomer precipitating peptide that may be useful to explore gene therapeutic approaches to Alzheimer disease. | Rejuvenation research 20120401 |
| Detection of α-synuclein aggregates by fluorescence microscopy. | Rejuvenation research 20120401 |
| Conformational changes during amyloid fibril formation of pancreatic thiol proteinase inhibitor: effect of copper and zinc. | Molecular biology reports 20120301 |
| Self assembly of human septin 2 into amyloid filaments. | Biochimie 20120301 |
| Morin hydrate inhibits amyloid formation by islet amyloid polypeptide and disaggregates amyloid fibers. | Protein science : a publication of the Protein Society 20120301 |
| Interaction of thioflavin T with amyloid fibrils: fluorescence quantum yield of bound dye. | The journal of physical chemistry. B 20120301 |
| Early detection of insulin fibrillation: a fluorescence lifetime assay to probe the pre-fibrillar regime. | Chemical communications (Cambridge, England) 20120227 |
| Role of the helical structure of the N-terminal region of Plasmodium falciparum merozoite surface protein 2 in fibril formation and membrane interaction. | Biochemistry 20120221 |
| Inhibiting effect of α(s1)-casein on Aβ(1-40) fibrillogenesis. | Biochimica et biophysica acta 20120201 |
| The effect of nanoparticles on amyloid aggregation depends on the protein stability and intrinsic aggregation rate. | Langmuir : the ACS journal of surfaces and colloids 20120124 |
| Aβ(39-42) modulates Aβ oligomerization but not fibril formation. | Biochemistry 20120110 |
| Existence of different structural intermediates and aggregates on the folding pathway of ovalbumin. | Journal of fluorescence 20120101 |
| A screening tool for therapeutic monoclonal antibodies: Identifying the most stable protein and its best formulation based on thioflavin T binding. | Biotechnology journal 20120101 |
| Inhibition of amyloid peptide fragment Aβ25-35 fibrillogenesis and toxicity by N-terminal β-amino acid-containing esapeptides: is taurine moiety essential for in vivo effects? | Chemical biology & drug design 20120101 |
| Prion protein polymerisation triggered by manganese-generated prion protein seeds. | Journal of neurochemistry 20120101 |
| Characterization, amyloid formation, and immobilization of a novel SGNH hydrolase from Listeria innocua 11262. | International journal of biological macromolecules 20120101 |
| Interference of low-molecular substances with the thioflavin-T fluorescence assay of amyloid fibrils. | Journal of peptide science : an official publication of the European Peptide Society 20120101 |
| Solid-state NMR reveals differences in the packing arrangements of peptide aggregates derived from the aortic amyloid polypeptide medin. | Journal of peptide science : an official publication of the European Peptide Society 20120101 |
| Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro. | Neurotoxicology 20120101 |
| SDS can be utilized as an amyloid inducer: a case study on diverse proteins. | PloS one 20120101 |
| Analyzing thioflavin T binding to amyloid fibrils by an equilibrium microdialysis-based technique. | PloS one 20120101 |
| Insights into the disparate action of osmolytes and macromolecular crowders on amyloid formation. | Prion 20120101 |
| Y145Stop is sufficient to induce de novo generation prions using protein misfolding cyclic amplification. | Prion 20120101 |
| Inhibition of aggregation of amyloid β42 by arginine-containing small compounds. | Bioscience, biotechnology, and biochemistry 20120101 |
| Establishing the links between Aβ aggregation and cytotoxicity in vitro using biophysical approaches. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Analysis of S100 oligomers and amyloids. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| S100A8/A9 amyloidosis in the ageing prostate: relating ex vivo and in vitro studies. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Histological staining of amyloid and pre-amyloid peptides and proteins in mouse tissue. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| The contrasting effect of macromolecular crowding on amyloid fibril formation. | PloS one 20120101 |
| Fibrillation of hen egg white lysozyme triggers reduction of copper(II). | International journal of biological macromolecules 20120101 |
| Doped diamond-like carbon coatings for surgical instruments reduce protein and prion-amyloid biofouling and improve subsequent cleaning. | Biofouling 20120101 |
| Fibril-forming motifs are essential and sufficient for the fibrillization of human Tau. | PloS one 20120101 |
| Synthesis and in vitro evaluation of fluorinated styryl benzazoles as amyloid-probes. | Bioorganic & medicinal chemistry 20111215 |
| Testing the therapeutic potential of doxycycline in a Drosophila melanogaster model of Alzheimer disease. | The Journal of biological chemistry 20111202 |
| Prefibrillar aggregates of yeast prion Sup35NM and its variant are toxic to mammalian cells. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20111201 |
| Dual conformation of H2H3 domain of prion protein in mammalian cells. | The Journal of biological chemistry 20111118 |
| A safe, blood-brain barrier permeable triphenylmethane dye inhibits amyloid-β neurotoxicity by generating nontoxic aggregates. | ACS chemical neuroscience 20111116 |
| Sensory network dysfunction, behavioral impairments, and their reversibility in an Alzheimer's β-amyloidosis mouse model. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20111102 |
| Role of oligomers in the amyloidogenesis of primary cutaneous amyloidosis. | Journal of the American Academy of Dermatology 20111101 |
| Inflammation protein SAA2.2 spontaneously forms marginally stable amyloid fibrils at physiological temperature. | Biochemistry 20111101 |
| Oligonucleotide-based label-free Hg2+ assay with a monomer-excimer fluorescence switch. | The Analyst 20111021 |
| Thioflavin T forms a non-fluorescent complex with α-helical poly-L-glutamic acid. | Chemical communications (Cambridge, England) 20111014 |
| Crocetin inhibits beta-amyloid fibrillization and stabilizes beta-amyloid oligomers. | Biochemical and biophysical research communications 20111014 |
| Interaction of thioflavin T with amyloid fibrils: stoichiometry and affinity of dye binding, absorption spectra of bound dye. | The journal of physical chemistry. B 20111006 |
| Nanotechnologies for Alzheimer's disease: diagnosis, therapy, and safety issues. | Nanomedicine : nanotechnology, biology, and medicine 20111001 |
| Resolution of localized small molecule-Aβ interactions by deep-ultraviolet resonance Raman spectroscopy. | Biophysical chemistry 20111001 |
| A novel mutation in transforming growth factor-beta induced protein (TGFβIp) reveals secondary structure perturbation in lattice corneal dystrophy. | The British journal of ophthalmology 20111001 |
| Synthesis and evaluation of ferrocenoyl pentapeptide (Fc-KLVFF) as an inhibitor of Alzheimer's Aβ₁-₄₂ fibril formation in vitro. | Bioorganic & medicinal chemistry letters 20111001 |
| Cucurbit[n]uril based supramolecular assemblies: tunable physico-chemical properties and their prospects. | Chemical communications (Cambridge, England) 20110928 |
| Designed hairpin peptides interfere with amyloidogenesis pathways: fibril formation and cytotoxicity inhibition, interception of the preamyloid state. | Biochemistry 20110927 |
| Inhibition of amyloid β aggregation and cytotoxicity by photodegradation using a designed fullerene derivative. | Chemistry, an Asian journal 20110905 |
| A standardized and biocompatible preparation of aggregate-free amyloid beta peptide for biophysical and biological studies of Alzheimer's disease. | Protein engineering, design & selection : PEDS 20110901 |
| Chiral superstructures of insulin amyloid fibrils. | Chirality 20110901 |
| Ligand polarizability contributes to tau fibril binding affinity. | Bioorganic & medicinal chemistry 20110901 |
| Modeling the nonradiative decay rate of electronically excited thioflavin T. | The journal of physical chemistry. A 20110804 |
| Hybrid hydrogels self-assembled from graft copolymers containing complementary β-sheets as hydroxyapatite nucleation scaffolds. | Biomaterials 20110801 |
| Targeting vascular amyloid in arterioles of Alzheimer disease transgenic mice with amyloid β protein antibody-coated nanoparticles. | Journal of neuropathology and experimental neurology 20110801 |
| Mechanism of amyloid β-protein aggregation mediated by GM1 ganglioside clusters. | Biochemistry 20110726 |
| Kinetic characterization of amyloid-beta 1-42 aggregation with a multimethodological approach. | Analytical biochemistry 20110715 |
| Probing the mechanism of insulin aggregation during agitation. | International journal of pharmaceutics 20110715 |
| Hexafluoroisopropanol induces amyloid fibrils of islet amyloid polypeptide by enhancing both hydrophobic and electrostatic interactions. | The Journal of biological chemistry 20110708 |
| Novel cell- and tissue-based assays for detecting misfolded and aggregated protein accumulation within aggresomes and inclusion bodies. | Cell biochemistry and biophysics 20110701 |
| Zinc, copper, and carnosine attenuate neurotoxicity of prion fragment PrP106-126. | Metallomics : integrated biometal science 20110701 |
| Acetonitrile can promote formation of different structural intermediate states on aggregation pathway of immunoglobulin G from human and bovine. | International journal of biological macromolecules 20110701 |
| The effect of red pigment on the amyloidization of yeast proteins. | Yeast (Chichester, England) 20110701 |
| Protein L-isoaspartyl O-methyltransferase inhibits amyloid beta fibrillogenesis in vitro. | Die Pharmazie 20110701 |
| A nano-confined charged layer defies the principle of electrostatic interaction. | Chemical communications (Cambridge, England) 20110628 |
| Pressure effect on the nonradiative process of thioflavin-T. | The journal of physical chemistry. A 20110623 |
| Study of thioflavin-T immobilized in porous silicon and the effect of different organic vapors on the fluorescence lifetime. | Langmuir : the ACS journal of surfaces and colloids 20110621 |
| Seed-dependent deposition behavior of Aβ peptides studied with wireless quartz-crystal-microbalance biosensor. | Analytical chemistry 20110615 |
| Binding modes of thioflavin T molecules to prion peptide assemblies identified by using scanning tunneling microscopy. | ACS chemical neuroscience 20110615 |
| Novel fluorescent trimethine cyanine dye 7519 for amyloid fibril inhibition assay. | Biotechnic & histochemistry : official publication of the Biological Stain Commission 20110601 |
| Nonnative aggregation of an IgG1 antibody in acidic conditions, part 2: nucleation and growth kinetics with competing growth mechanisms. | Journal of pharmaceutical sciences 20110601 |
| Nonnative aggregation of an IgG1 antibody in acidic conditions: part 1. Unfolding, colloidal interactions, and formation of high-molecular-weight aggregates. | Journal of pharmaceutical sciences 20110601 |
| Insight into amyloid structure using chemical probes. | Chemical biology & drug design 20110601 |
| Design and evaluation of a 6-mer amyloid-beta protein derived phage display library for molecular targeting of amyloid plaques in Alzheimer's disease: Comparison with two cyclic heptapeptides derived from a randomized phage display library. | Peptides 20110601 |
| Coumarin 6 and 1,6-diphenyl-1,3,5-hexatriene (DPH) as fluorescent probes to monitor protein aggregation. | The Analyst 20110521 |
| Rhodanine and thiohydantoin derivatives for detecting tau pathology in Alzheimer's brains. | ACS chemical neuroscience 20110518 |
| Influence of protein hydrolysis on the growth kinetics of β-lg fibrils. | Langmuir : the ACS journal of surfaces and colloids 20110517 |
| The Osaka FAD mutation E22Δ leads to the formation of a previously unknown type of amyloid β fibrils and modulates Aβ neurotoxicity. | Journal of molecular biology 20110513 |
| Monitoring the aggregation processes of amyloid-β using a spin-labeled, fluorescent nitroxyl radical. | Chemical communications (Cambridge, England) 20110507 |
| Interactions of Npc1 and amyloid accumulation/deposition in the APP/PS1 mouse model of Alzheimer's. | Journal of applied genetics 20110501 |
| High ability of apolipoprotein E4 to stabilize amyloid-β peptide oligomers, the pathological entities responsible for Alzheimer's disease. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110501 |
| Cerebral amyloid angiopathy in streptozotocin rat model of sporadic Alzheimer's disease: a long-term follow up study. | Journal of neural transmission (Vienna, Austria : 1996) 20110501 |
| Sequence-independent control of peptide conformation in liposomal vaccines for targeting protein misfolding diseases. | The Journal of biological chemistry 20110422 |
| A modified protocol to prepare seed-free starting solutions of amyloid-β (Aβ)₁₋₄₀ and Aβ₁₋₄₂ from the corresponding depsipeptides. | Analytical biochemistry 20110415 |
| Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan. | Nature 20110414 |
| Biflavonoids are superior to monoflavonoids in inhibiting amyloid-β toxicity and fibrillogenesis via accumulation of nontoxic oligomer-like structures. | Biochemistry 20110405 |
| Heparin binds 8 kDa gelsolin cross-β-sheet oligomers and accelerates amyloidogenesis by hastening fibril extension. | Biochemistry 20110405 |
| Spectroscopic characterization of diverse amyloid fibrils in vitro by the fluorescent dye Nile red. | Molecular bioSystems 20110401 |
| Bovine Serum Albumin protofibril-like aggregates formation: solo but not simple mechanism. | Archives of biochemistry and biophysics 20110401 |
| The effect of tachykinin neuropeptides on amyloid β aggregation. | Biochemical and biophysical research communications 20110401 |
| A new look at old compounds. | Aging 20110401 |
| Temperature dependence of the fluorescence properties of thioflavin-T in propanol, a glass-forming liquid. | The journal of physical chemistry. A 20110331 |
| Amyloid fibrils formation of concanavalin A at basic pH. | The journal of physical chemistry. B 20110331 |
| The Japanese mutant Aβ (ΔE22-Aβ(1-39)) forms fibrils instantaneously, with low-thioflavin T fluorescence: seeding of wild-type Aβ(1-40) into atypical fibrils by ΔE22-Aβ(1-39). | Biochemistry 20110329 |
| Destruction of amyloid fibrils of keratoepithelin peptides by laser irradiation coupled with amyloid-specific thioflavin T. | The Journal of biological chemistry 20110325 |
| Detecting the early onset of shear-induced fibril formation of insulin in situ. | The journal of physical chemistry. B 20110324 |
| Structural evolution of Iowa mutant β-amyloid fibrils from polymorphic to homogeneous states under repeated seeded growth. | Journal of the American Chemical Society 20110323 |
| Electrochemical detection of interaction between Thioflavin T and acetylcholinesterase. | The Analyst 20110321 |
| On the origin of the stronger binding of PIB over thioflavin T to protofibrils of the Alzheimer amyloid-β peptide: a molecular dynamics study. | Biophysical journal 20110302 |
| Characterization of the non-fibrillar α-synuclein oligomers. | Protein and peptide letters 20110301 |
| Use of yeast as a system to study amyloid toxicity. | Methods (San Diego, Calif.) 20110301 |
| Studying the effects of chaperones on amyloid fibril formation. | Methods (San Diego, Calif.) 20110301 |
| Assays for studying nucleated aggregation of polyglutamine proteins. | Methods (San Diego, Calif.) 20110301 |
| Both plant and animal LEA proteins act as kinetic stabilisers of polyglutamine-dependent protein aggregation. | FEBS letters 20110218 |
| Evaluation of aluminium, manganese, copper and selenium effects on human islets amyloid polypeptide hormone aggregation. | Pakistan journal of biological sciences : PJBS 20110215 |
| The role of the C-terminus of human α-synuclein: intra-disulfide bonds between the C-terminus and other regions stabilize non-fibrillar monomeric isomers. | FEBS letters 20110204 |
| Stereospecific interactions are necessary for Alzheimer disease amyloid-β toxicity. | Neurobiology of aging 20110201 |
| Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion. | Nature medicine 20110201 |
| Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity, recapitulating key features of FUS proteinopathy. | Protein & cell 20110201 |
| Synthesis and biophysical evaluation of arylhydrazono-1H-2-indolinones as β-amyloid aggregation inhibitors. | European journal of medicinal chemistry 20110101 |
| Curcuminoid binds to amyloid-β1-42 oligomer and fibril. | Journal of Alzheimer's disease : JAD 20110101 |
| The regulatory subunit of PKA-I remains partially structured and undergoes β-aggregation upon thermal denaturation. | PloS one 20110101 |
| A role for amyloid in cell aggregation and biofilm formation. | PloS one 20110101 |
| Calcium ions promote formation of amyloid β-peptide (1-40) oligomers causally implicated in neuronal toxicity of Alzheimer's disease. | PloS one 20110101 |
| Non-esterified fatty acids generate distinct low-molecular weight amyloid-β (Aβ42) oligomers along pathway different from fibril formation. | PloS one 20110101 |
| Conformational stability and aggregation of therapeutic monoclonal antibodies studied with ANS and Thioflavin T binding. | mAbs 20110101 |
| Diagnostics for amyloid fibril formation: where to begin? | Methods in molecular biology (Clifton, N.J.) 20110101 |
| Lack of LDL receptor enhances amyloid deposition and decreases glial response in an Alzheimer's disease mouse model. | PloS one 20110101 |
| Human apolipoprotein A-I-derived amyloid: its association with atherosclerosis. | PloS one 20110101 |
| Molecular interaction of TPPP with PrP antagonized the CytoPrP-induced disruption of microtubule structures and cytotoxicity. | PloS one 20110101 |
| The mechanism of enhanced insulin amyloid fibril formation by NaCl is better explained by a conformational change model. | PloS one 20110101 |
| [The effect of red pigment of Saccharomyces cerevisiae on insulin fibril formation in vitro]. | Tsitologiia 20110101 |
| Proline periodicity modulates the self-assembly properties of elastin-like polypeptides. | The Journal of biological chemistry 20101217 |
| Comparative effects of pH and ionic strength on protein-protein interactions, unfolding, and aggregation for IgG1 antibodies. | Journal of pharmaceutical sciences 20101201 |
| The kinetic parameters and energy cost of the Hsp70 chaperone as a polypeptide unfoldase. | Nature chemical biology 20101201 |
| Interactions between amyloidophilic dyes and their relevance to studies of amyloid inhibitors. | Biophysical journal 20101117 |
| Synthesis and evaluation of stilbene derivatives as a potential imaging agent of amyloid plaques. | Bioorganic & medicinal chemistry 20101115 |
| Amyloid-binding small molecules efficiently block SEVI (semen-derived enhancer of virus infection)- and semen-mediated enhancement of HIV-1 infection. | The Journal of biological chemistry 20101112 |
| Protective effects of galantamine against Abeta-induced PC12 cell apoptosis by preventing mitochondrial dysfunction and endoplasmic reticulum stress. | Neurochemistry international 20101101 |
| Granular and lattice deposits in corneal dystrophy caused by R124C mutation of TGFBIp. | Cornea 20101101 |
| Attenuated antiaggregation effects of magnetite nanoparticles in cerebrospinal fluid of people with Alzheimer's disease. | Molecular bioSystems 20101101 |
| Reduction of hippocampal N-acetyl aspartate level in aged APP(Swe)/PS1(dE9) transgenic mice is associated with degeneration of CA3 pyramidal neurons. | Journal of neuroscience research 20101101 |
| I32E and V36K double mutation in beta2-sheet abrogates amyloid beta peptide toxicity. | Indian journal of experimental biology 20101101 |
| Amyloid-binding small molecule reduces HIV infection. | Future medicinal chemistry 20101101 |
| Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio. | The EMBO journal 20101006 |
| Fibrillation of alpha-lactalbumin: effect of crocin and safranal, two natural small molecules from Crocus sativus. | Biopolymers 20101001 |
| Highly sensitive amyloid detection enabled by thioflavin T dimers. | Molecular bioSystems 20101001 |
| Isolation of short peptide fragments from alpha-synuclein fibril core identifies a residue important for fibril nucleation: a possible implication for diagnostic applications. | Biochimica et biophysica acta 20101001 |
| Amyloid formation and disaggregation of α-synuclein and its tandem repeat (α-TR). | Biochemical and biophysical research communications 20101001 |
| The flavanol (-)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP-induced toxicity. | Biochemistry 20100921 |
| Molecular basis of inhibition of substrate hydrolysis by a ligand bound to the peripheral site of acetylcholinesterase. | Chemico-biological interactions 20100906 |
| Self-assembling pathway of HiApp fibrils within lipid bilayers. | Chembiochem : a European journal of chemical biology 20100903 |
| Quantifying prefibrillar amyloids in vitro by using a 'thioflavin-like' spectroscopic method. | Chembiochem : a European journal of chemical biology 20100903 |
| Alzheimer's disease: spect and pet tracers for beta-amyloid imaging. | Current Alzheimer research 20100901 |
| A beta-amino acid modified heptapeptide containing a designed recognition element disrupts fibrillization of the amyloid beta-peptide. | Journal of peptide science : an official publication of the European Peptide Society 20100901 |
| Charge transfer process determines ultrafast excited state deactivation of thioflavin T in low-viscosity solvents. | The journal of physical chemistry. A 20100819 |
| Identifying the bond responsible for the fluorescence modulation in an amyloid fibril sensor. | Chemistry (Weinheim an der Bergstrasse, Germany) 20100809 |
| The amyloid fibrils of the constant domain of immunoglobulin light chain. | FEBS letters 20100804 |
| L-Arginine reduces thioflavin T fluorescence but not fibrillation of bovine serum albumin. | Amino acids 20100801 |
| beta-Sheet aggregation of kisspeptin-10 is stimulated by heparin but inhibited by amphiphiles. | Biopolymers 20100801 |
| Abeta20-29 peptide blocking apoE/Abeta interaction reduces full-length Abeta42/40 fibril formation and cytotoxicity in vitro. | Neuropeptides 20100801 |
| Activation of phospholipase A2 by 1-palmitoyl-2-(9'-oxo-nonanoyl)-sn-glycero-3-phosphocholine in vitro. | Biochimica et biophysica acta 20100801 |
| Resveratrol selectively remodels soluble oligomers and fibrils of amyloid Abeta into off-pathway conformers. | The Journal of biological chemistry 20100730 |
| The dissociated form of kappa-casein is the precursor to its amyloid fibril formation. | The Biochemical journal 20100715 |
| Substoichiometric inhibition of Abeta(1-40) aggregation by a tandem Abeta(40-1-Gly8-1-40) peptide. | Biochemical and biophysical research communications 20100702 |
| Domain a' of protein disulfide isomerase plays key role in inhibiting alpha-synuclein fibril formation. | Cell stress & chaperones 20100701 |
| Molecular mechanism of Thioflavin-T binding to amyloid fibrils. | Biochimica et biophysica acta 20100701 |
| Analysis of monomeric Abeta (1-40) peptide by capillary electrophoresis. | The Analyst 20100701 |
| Bifurcated hydrogen bonds stabilize fibrils of poly(L-glutamic) acid. | The journal of physical chemistry. B 20100624 |
| Laser-induced propagation and destruction of amyloid beta fibrils. | The Journal of biological chemistry 20100618 |
| Complement protein C1q forms a complex with cytotoxic prion protein oligomers. | The Journal of biological chemistry 20100618 |
| Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease. | Movement disorders : official journal of the Movement Disorder Society 20100615 |
| The role of the lipid bilayer in tau aggregation. | Biophysical journal 20100602 |
| Oligomers of beta-amyloid are sequestered into and seed new plaques in the brains of an AD mouse model. | Experimental neurology 20100601 |
| Density functional theory analysis and spectral studies on amyloid peptide Abeta(28-35) and its mutants A30G and A30I. | Journal of structural biology 20100601 |
| Catechol derivatives inhibit the fibril formation of amyloid-beta peptides. | Journal of bioscience and bioengineering 20100601 |
| Dose- and time-dependent alpha-synuclein aggregation induced by ferric iron in SK-N-SH cells. | Neuroscience bulletin 20100601 |
| Multidimensional structure-activity relationship of a protein in its aggregated states. | Angewandte Chemie (International ed. in English) 20100525 |
| Strategies to increase the reproducibility of protein fibrillization in plate reader assays. | Analytical biochemistry 20100515 |
| Burden of neurodegenerative diseases in a cohort of medical examiner subjects. | Journal of forensic sciences 20100501 |
| Whole-body biodistribution and brain PET imaging with [18F]AV-45, a novel amyloid imaging agent--a pilot study. | Nuclear medicine and biology 20100501 |
| PB1-F2 influenza A virus protein adopts a beta-sheet conformation and forms amyloid fibers in membrane environments. | The Journal of biological chemistry 20100423 |
| Intrinsic determinants of neurotoxic aggregate formation by the amyloid beta peptide. | Biophysical journal 20100421 |
| Development of a proteolytically stable retro-inverso peptide inhibitor of beta-amyloid oligomerization as a potential novel treatment for Alzheimer's disease. | Biochemistry 20100420 |
| Molecular polymorphism of Abeta in Alzheimer's disease. | Neurobiology of aging 20100401 |
| Critical role of interfaces and agitation on the nucleation of Abeta amyloid fibrils at low concentrations of Abeta monomers. | Biochimica et biophysica acta 20100401 |
| A novel, high-efficiency cellular model of fibrillar alpha-synuclein inclusions and the examination of mutations that inhibit amyloid formation. | Journal of neurochemistry 20100401 |
| Design, synthesis and biological evaluation of indane-2-arylhydrazinylmethylene-1,3-diones and indol-2-aryldiazenylmethylene-3-ones as beta-amyloid aggregation inhibitors. | European journal of medicinal chemistry 20100401 |
| Curcumin labeling of neuronal fibrillar tau inclusions in human brain samples. | Journal of neuropathology and experimental neurology 20100401 |
| Supramolecular capsules: under control. | Nature chemistry 20100401 |
| The interaction of alphaB-crystallin with mature alpha-synuclein amyloid fibrils inhibits their elongation. | Biophysical journal 20100303 |
| Yeast cell adhesion molecules have functional amyloid-forming sequences. | Eukaryotic cell 20100301 |
| DnaK/DnaJ/GrpE of Hsp70 system have differing effects on alpha-synuclein fibrillation involved in Parkinson's disease. | International journal of biological macromolecules 20100301 |
| Ultrafast bond twisting dynamics in amyloid fibril sensor. | The journal of physical chemistry. B 20100225 |
| Crystal structure of thioflavin-T and its binding to amyloid fibrils: insights at the molecular level. | Chemical communications (Cambridge, England) 20100221 |
| Probing the amyloid-beta(1-40) fibril environment with substituted tryptophan residues. | Archives of biochemistry and biophysics 20100215 |
| Lability landscape and protease resistance of human insulin amyloid: a new insight into its molecular properties. | Journal of molecular biology 20100212 |
| Cooperative metal ion binding to a cucurbit[7]uril-thioflavin T complex: demonstration of a stimulus-responsive fluorescent supramolecular capsule. | Journal of the American Chemical Society 20100203 |
| Modulation of aggregate size- and shape-distributions of the amyloid-beta peptide by a designed beta-sheet breaker. | European biophysics journal : EBJ 20100201 |
| Role of zinc along with ascorbic acid and folic acid during long-term in vitro albumin glycation. | The British journal of nutrition 20100201 |
| Thioflavin T fluorescence in human serum: correlations with vascular health and cardiovascular risk factors. | Clinical biochemistry 20100201 |
| Novel anilinophthalimide derivatives as potential probes for beta-amyloid plaque in the brain. | Bioorganic & medicinal chemistry 20100201 |
| Interaction between oligomers of stefin B and amyloid-beta in vitro and in cells. | The Journal of biological chemistry 20100129 |
| Oligomerization and insulin interactions of proinsulin C-peptide: Threefold relationships to properties of insulin. | Biochemical and biophysical research communications 20100115 |
| Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus. | Neurobiology of disease 20100101 |
| Inhibition of beta 1-40 amyloid fibrillation with N-acetyl-L-cysteine capped quantum dots. | Biomaterials 20100101 |
| Searching for conditions to form stable protein oligomers with amyloid-like characteristics: The unexplored basic pH. | Biochimica et biophysica acta 20100101 |
| Amyloid formation: age-related mechanism in Creutzfeldt-Jakob disease? | Rejuvenation research 20100101 |
| The therapeutic effects of the herbal medicine, Juzen-taiho-to, on amyloid-beta burden in a mouse model of Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20100101 |
| The interaction of humic substances with the human prion protein fragment 90-231 affects its protease K resistance and cell internalization. | Journal of biological regulators and homeostatic agents 20100101 |
| Superoxide dismutase 1 and tgSOD1 mouse spinal cord seed fibrils, suggesting a propagative cell death mechanism in amyotrophic lateral sclerosis. | PloS one 20100101 |
| Three repeat isoforms of tau inhibit assembly of four repeat tau filaments. | PloS one 20100101 |
| Immunohistological detection of Chlamydia pneumoniae in the Alzheimer's disease brain. | BMC neuroscience 20100101 |
| Fluorescence quantum yield of thioflavin T in rigid isotropic solution and incorporated into the amyloid fibrils. | PloS one 20100101 |
| Β-amyloid 1-42 oligomers impair function of human embryonic stem cell-derived forebrain cholinergic neurons. | PloS one 20100101 |
| [Thioflavin T interaction with amyloid fibrils as an instrument for their studying]. | Tsitologiia 20100101 |
| Binding modes of thioflavin-T to the single-layer beta-sheet of the peptide self-assembly mimics. | Journal of molecular biology 20091211 |
| Fibril fragmentation enhances amyloid cytotoxicity. | The Journal of biological chemistry 20091204 |
| Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide. | Proceedings of the National Academy of Sciences of the United States of America 20091201 |
| Impaired processing of human pro-islet amyloid polypeptide is not a causative factor for fibril formation or membrane damage in vitro. | Biochemistry 20091124 |
| Tyrosine autofluorescence as a measure of bovine insulin fibrillation. | Biophysical journal 20091104 |
| Abeta peptide conformation determines uptake and interleukin-1alpha expression by primary microglial cells. | Neurobiology of aging 20091101 |
| Thioflavin S (NSC71948) interferes with Bcl-2-associated athanogene (BAG-1)-mediated protein-protein interactions. | The Journal of pharmacology and experimental therapeutics 20091101 |
| Resveratrol inhibits beta-amyloid oligomeric cytotoxicity but does not prevent oligomer formation. | Neurotoxicology 20091101 |
| Revealing of Saccharomyces cerevisiae yeast cell wall proteins capable of binding thioflavin T, a fluorescent dye specifically interacting with amyloid fibrils. | Biochemistry. Biokhimiia 20091101 |
| Effects of non-steroidal anti-inflammatory drugs on Abeta deposition in Abeta(1-42) transgenic C. elegans. | Brain research 20091027 |
| Kinetic analysis of amyloid formation in the presence of heparan sulfate: faster unfolding and change of pathway. | The Journal of biological chemistry 20091023 |
| Formation mechanism of insulin fibrils and structural aspects of the insulin fibrillation process. | Current protein & peptide science 20091001 |
| Effect of curcumin on amyloidogenic property of molten globule-like intermediate state of 2,5-diketo-D-gluconate reductase A. | Biological chemistry 20091001 |
| Mechanism of docosahexaenoic acid-induced inhibition of in vitro Abeta1-42 fibrillation and Abeta1-42-induced toxicity in SH-S5Y5 cells. | Journal of neurochemistry 20091001 |
| Morphology of self-assembled structures formed by short peptides from the amyloidogenic protein tau depends on the solvent in which the peptides are dissolved. | Journal of peptide science : an official publication of the European Peptide Society 20091001 |
| The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds. | The FEBS journal 20091001 |
| Interactions of thioflavin T with serum albumins: spectroscopic analyses. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090915 |
| The functional curli amyloid is not based on in-register parallel beta-sheet structure. | The Journal of biological chemistry 20090911 |
| Near-field scanning optical microscopy measurements of fluorescent molecular probes binding to insulin amyloid fibrils. | The journal of physical chemistry. B 20090903 |
| On the stability of the soluble amyloid aggregates. | Biophysical journal 20090902 |
| Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease. | Neurobiology of disease 20090901 |
| Zn(II)- and Cu(II)-induced non-fibrillar aggregates of amyloid-beta (1-42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators. | Journal of neurochemistry 20090901 |
| A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta. | Bioorganic & medicinal chemistry letters 20090901 |
| Structural characterization of clusterin-chaperone client protein complexes. | The Journal of biological chemistry 20090814 |
| A New Transgenic Mouse Model of Gerstmann-Straussler-Scheinker Syndrome Caused by the A117V Mutation of PRNP. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090812 |
| Self-assembled hydrogels from poly[N-(2-hydroxypropyl)methacrylamide] grafted with beta-sheet peptides. | Biomacromolecules 20090810 |
| Self-organization pathways and spatial heterogeneity in insulin amyloid fibril formation. | The journal of physical chemistry. B 20090806 |
| Comparative study of inhibition at multiple stages of amyloid-beta self-assembly provides mechanistic insight. | Molecular pharmacology 20090801 |
| D-Ribosylated Tau forms globular aggregates with high cytotoxicity. | Cellular and molecular life sciences : CMLS 20090801 |
| Inhibition of Abeta42 aggregation using peptides selected from combinatorial libraries. | Journal of peptide science : an official publication of the European Peptide Society 20090801 |
| Evidence for novel beta-sheet structures in Iowa mutant beta-amyloid fibrils. | Biochemistry 20090707 |
| Ultrafast torsional dynamics of protein binding dye thioflavin-T in nanoconfined water pool. | The journal of physical chemistry. B 20090625 |
| Parcellation of human temporal polar cortex: a combined analysis of multiple cytoarchitectonic, chemoarchitectonic, and pathological markers. | The Journal of comparative neurology 20090620 |
| Amyloid fibril-like structure underlies the aggregate structure across the pH range for beta-lactoglobulin. | Biophysical journal 20090617 |
| The polyphenol piceid destabilizes preformed amyloid fibrils and oligomers in vitro: hypothesis on possible molecular mechanisms. | Neurochemical research 20090601 |
| Anti-aggregation and fibril-destabilizing effects of sex hormones on alpha-synuclein fibrils in vitro. | Experimental neurology 20090601 |
| Detection of interactions of the beta-amyloid peptide with small molecules employing transferred NOEs. | Journal of peptide science : an official publication of the European Peptide Society 20090601 |
| Neuronal response of peroxisomal and peroxisome-related proteins to chronic and acute Abeta injury. | Current Alzheimer research 20090601 |
| Rapid aggregation and assembly in aqueous solution of A beta (25-35) peptide. | Journal of biosciences 20090601 |
| Amyloid beta (1-42) folding multiplicity and single-molecule binding behavior studied with STM. | Journal of molecular biology 20090515 |
| Dissecting the mechanisms of tissue transglutaminase-induced cross-linking of alpha-synuclein: implications for the pathogenesis of Parkinson disease. | The Journal of biological chemistry 20090508 |
| Characterization of type I collagen fibril formation using thioflavin T fluorescent dye. | Journal of biochemistry 20090501 |
| Synthetic lipid vesicles recruit native-like aggregates and affect the aggregation process of the prion Ure2p: insights on vesicle permeabilization and charge selectivity. | Biophysical journal 20090422 |
| Bovine insulin filaments induced by reducing disulfide bonds show a different morphology, secondary structure, and cell toxicity from intact insulin amyloid fibrils. | Biophysical journal 20090422 |
| CE can identify small molecules that selectively target soluble oligomers of amyloid beta protein and display antifibrillogenic activity. | Electrophoresis 20090401 |
| Effects of docosahexaenoic acid on in vitro amyloid beta peptide 25-35 fibrillation. | Biochimica et biophysica acta 20090401 |
| Agitation and high ionic strength induce amyloidogenesis of a folded PDZ domain in native conditions. | Biophysical journal 20090318 |
| Existence of different structural intermediates on the fibrillation pathway of human serum albumin. | Biophysical journal 20090318 |
| Real-time analysis of amyloid fibril formation of alpha-synuclein using a fibrillation-state-specific fluorescent probe of JC-1. | The Biochemical journal 20090301 |
| Thioflavin T fluorescence assay for beta-lactoglobulin fibrils hindered by DAPH. | Journal of structural biology 20090301 |
| Photophysical studies on the noncovalent interaction of thioflavin T with cucurbit[n]uril macrocycles. | The journal of physical chemistry. B 20090219 |
| Design, selection, and characterization of thioflavin-based intercalation compounds with metal chelating properties for application in Alzheimer's disease. | Journal of the American Chemical Society 20090204 |
| The mechanism of amyloid-fibril formation by stefin B: temperature and protein concentration dependence of the rates. | Proteins 20090201 |
| Beta-amyloid deposition and functional impairment in the retina of the APPswe/PS1DeltaE9 transgenic mouse model of Alzheimer's disease. | Investigative ophthalmology & visual science 20090201 |
| Proteolysis of prion protein by cathepsin S generates a soluble beta-structured intermediate oligomeric form, with potential implications for neurotoxic mechanisms. | European biophysics journal : EBJ 20090201 |
| Smoking and Parkinson's disease: does nicotine affect alpha-synuclein fibrillation? | Biochimica et biophysica acta 20090201 |
| Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease. | Neurochemistry international 20090201 |
| Synthesis and biological evaluation of radioiodinated 2NUBTA as a cerebral ischemia marker. | Bioorganic & medicinal chemistry letters 20090201 |
| Molecular mechanism of thioflavin-T binding to the surface of beta-rich peptide self-assemblies. | Journal of molecular biology 20090130 |
| A new amyloid-like beta-aggregate with amyloid characteristics, except fibril morphology. | Journal of molecular biology 20090130 |
| Ovine colostrum nanopeptide affects amyloid beta aggregation. | FEBS letters 20090105 |
| Garlic extract exhibits antiamyloidogenic activity on amyloid-beta fibrillogenesis: relevance to Alzheimer's disease. | Phytotherapy research : PTR 20090101 |
| Cytoskeletal alterations differentiate presenilin-1 and sporadic Alzheimer's disease. | Acta neuropathologica 20090101 |
| Aggregate formation and toxicity by wild-type and R621C synphilin-1 in the nigrostriatal system of mice using adenoviral vectors. | Journal of neurochemistry 20090101 |
| Amyloid oligomers in diabetic and nondiabetic human pancreas. | Translational research : the journal of laboratory and clinical medicine 20090101 |
| Tertiary butanol induced amyloidogenesis of hen egg white lysozyme (HEWL) is facilitated by aggregation-prone alkali-induced molten globule like conformational state. | Protein and peptide letters 20090101 |
| Development of tau aggregation inhibitors for Alzheimer's disease. | Angewandte Chemie (International ed. in English) 20090101 |
| The synthesis and characterization of [(124)I]IMPY, a thioflavin-S derivative, in transgenic mouse models of Alzheimer's disease. | Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20090101 |
| Rapid method for measurement of acetylcholinesterase activity. | Bulletin of experimental biology and medicine 20090101 |
| Fibrils from designed non-amyloid-related synthetic peptides induce AA-amyloidosis during inflammation in an animal model. | PloS one 20090101 |
| Copper abolishes the beta-sheet secondary structure of preformed amyloid fibrils of amyloid-beta(42). | Journal of Alzheimer's disease : JAD 20090101 |
| RNA aptamers generated against oligomeric Abeta40 recognize common amyloid aptatopes with low specificity but high sensitivity. | PloS one 20090101 |
| Mechanically functional amyloid fibrils in the adhesive of a marine invertebrate as revealed by Raman spectroscopy and atomic force microscopy. | Archives of histology and cytology 20090101 |
| The binding of thioflavin T and its neutral analog BTA-1 to protofibrils of the Alzheimer's disease Abeta(16-22) peptide probed by molecular dynamics simulations. | Journal of molecular biology 20081219 |
| Thioflavin T as a molecular rotor: fluorescent properties of thioflavin T in solvents with different viscosity. | The journal of physical chemistry. B 20081211 |
| Analysis of the reaction of carbachol with acetylcholinesterase using thioflavin T as a coupled fluorescence reporter. | Biochemistry 20081209 |
| Intracranial administration of vaccinia virus complement control protein in Mo/Hu APPswe PS1dE9 transgenic mice at an early age shows enhanced performance at a later age using a cheese board maze test. | Biogerontology 20081201 |
| Docosahexaenoic acid disrupts in vitro amyloid beta(1-40) fibrillation and concomitantly inhibits amyloid levels in cerebral cortex of Alzheimer's disease model rats. | Journal of neurochemistry 20081201 |
| Formation of highly toxic soluble amyloid beta oligomers by the molecular chaperone prefoldin. | The FEBS journal 20081201 |
| Thioflavin T hydroxylation at basic pH and its effect on amyloid fibril detection. | The journal of physical chemistry. B 20081127 |
| Effects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicity. | The Journal of biological chemistry 20081121 |
| Sulfated polysaccharides promote the assembly of amyloid beta(1-42) peptide into stable fibrils of reduced cytotoxicity. | The Journal of biological chemistry 20081121 |
| Thioflavin T displays enhanced fluorescence selectively inside anionic micelles and mammalian cells. | Journal of fluorescence 20081101 |
| Aggregation and conformational studies on a pentapeptide derivative. | Biochimica et biophysica acta 20081101 |
| Thiazin red as a neuropathological tool for the rapid diagnosis of Alzheimer's disease in tissue imprints. | Acta neuropathologica 20081101 |
| Aggregates assembled from overexpression of wild-type alpha-synuclein are not toxic to human neuronal cells. | Journal of neuropathology and experimental neurology 20081101 |
| The ratio of monomeric to aggregated forms of Abeta40 and Abeta42 is an important determinant of amyloid-beta aggregation, fibrillogenesis, and toxicity. | The Journal of biological chemistry 20081017 |
| Aminostyrylbenzofuran derivatives as potent inhibitors for Abeta fibril formation. | Bioorganic & medicinal chemistry letters 20081015 |
| Cyanidin 3-O-glucopyranoside protects and rescues SH-SY5Y cells against amyloid-beta peptide-induced toxicity. | Neuroreport 20081008 |
| Thermally induced denaturation and aggregation of BLG-A: effect of the Cu(2+) and Zn (2+) metal ions. | European biophysics journal : EBJ 20081001 |
| Acrolein, the toxic endogenous aldehyde, induces neurofilament-L aggregation. | BMB reports 20080930 |
| Monitoring the reaction of carbachol with acetylcholinesterase by thioflavin T fluorescence and acetylthiocholine hydrolysis. | Chemico-biological interactions 20080925 |
| Beta-lactoglobulin assembles into amyloid through sequential aggregated intermediates. | Journal of molecular biology 20080919 |
| Different inhibitory response of cyanidin and methylene blue for filament formation of tau microtubule-binding domain. | Biochemical and biophysical research communications 20080912 |
| Acridine derivatives inhibit lysozyme aggregation. | European biophysics journal : EBJ 20080901 |
| Role of conformational change in the C-terminus of beta2-microglobulin in dialysis-related amyloidosis. | Annals of clinical biochemistry 20080901 |
| Characterization of amyloidogenesis of hen egg lysozyme in concentrated ethanol solution. | Biochemical and biophysical research communications 20080815 |
| Role of trehalose in moisture-induced aggregation of bovine serum albumin. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080801 |
| Altered binding of thioflavin t to the peripheral anionic site of acetylcholinesterase after phosphorylation of the active site by chlorpyrifos oxon or dichlorvos. | Toxicology and applied pharmacology 20080801 |
| Tg-SwDI transgenic mice exhibit novel alterations in AbetaPP processing, Abeta degradation, and resilient amyloid angiopathy. | The American journal of pathology 20080801 |
| Corticosterone and related receptor expression are associated with increased beta-amyloid plaques in isolated Tg2576 mice. | Neuroscience 20080731 |
| Lipid-derived aldehydes accelerate light chain amyloid and amorphous aggregation. | Biochemistry 20080722 |
| Water-soluble tripeptide Abeta (9-11) forms amyloid-like fibrils and exhibits neurotoxicity. | Organic letters 20080703 |
| Unfolding and aggregation of transthyretin by the truncation of 50 N-terminal amino acids. | Proteins 20080701 |
| Alpha-synuclein aggregation and cell death triggered by energy deprivation and dopamine overload are counteracted by D2/D3 receptor activation. | Journal of neurochemistry 20080701 |
| Molecular understanding of copper and iron interaction with alpha-synuclein by fluorescence analysis. | Journal of molecular neuroscience : MN 20080701 |
| Dimorphic aggregation behavior of a fusion polypeptide incorporating a stable protein domain (EGFP) with an amyloidogenic sequence (retroCspA). | FEBS letters 20080625 |
| Crystal structure of thioflavin T bound to the peripheral site of Torpedo californica acetylcholinesterase reveals how thioflavin T acts as a sensitive fluorescent reporter of ligand binding to the acylation site. | Journal of the American Chemical Society 20080625 |
| Posterior parahippocampal gyrus pathology in Alzheimer's disease. | Neuroscience 20080623 |
| The fluorescent amino acid p-cyanophenylalanine provides an intrinsic probe of amyloid formation. | Chembiochem : a European journal of chemical biology 20080616 |
| Rifampicin does not prevent amyloid fibril formation by human islet amyloid polypeptide but does inhibit fibril thioflavin-T interactions: implications for mechanistic studies of beta-cell death. | Biochemistry 20080603 |
| Formation of amyloid fibrils by bovine carbonic anhydrase. | Biochimica et biophysica acta 20080601 |
| On the binding of Thioflavin-T to HET-s amyloid fibrils assembled at pH 2. | Journal of structural biology 20080601 |
| The flexible C terminus of the rotavirus non-structural protein NSP4 is an important determinant of its biological properties. | The Journal of general virology 20080601 |
| Effects of amyloid-beta peptides on hydrogen peroxide-metabolizing enzymes in rat brain in vivo. | Free radical research 20080601 |
| Chiral bifurcation in aggregating insulin: an induced circular dichroism study. | Journal of molecular biology 20080523 |
| The formation of a novel supramolecular structure by amyloid of poly-L-glutamic acid. | Biochemical and biophysical research communications 20080509 |
| The (1-63) region of the p53 transactivation domain aggregates in vitro into cytotoxic amyloid assemblies. | Biophysical journal 20080501 |
| Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers. | The Journal of biological chemistry 20080418 |
| A multimeric quinacrine conjugate as a potential inhibitor of Alzheimer's beta-amyloid fibril formation. | Chembiochem : a European journal of chemical biology 20080414 |
| Dissociation from the oligomeric state is the rate-limiting step in fibril formation by kappa-casein. | The Journal of biological chemistry 20080404 |
| The degree of structural protection at the edge beta-strands determines the pathway of amyloid formation in globular proteins. | Journal of the American Chemical Society 20080402 |
| Accelerated release of exosome-associated GM1 ganglioside (GM1) by endocytic pathway abnormality: another putative pathway for GM1-induced amyloid fibril formation. | Journal of neurochemistry 20080401 |
| Inhibition of cytotoxicity and amyloid fibril formation by a D-amino acid peptide that specifically binds to Alzheimer's disease amyloid peptide. | Protein engineering, design & selection : PEDS 20080401 |
| Cu(II) organizes beta-2-microglobulin oligomers but is released upon amyloid formation. | Protein science : a publication of the Protein Society 20080401 |
| Secondary nucleation and accessible surface in insulin amyloid fibril formation. | The journal of physical chemistry. B 20080327 |
| Ligand-induced flocculation of neurotoxic fibrillar Abeta(1-42) by noncovalent crosslinking. | Chembiochem : a European journal of chemical biology 20080325 |
| Amyloid fibril formation by bovine milk alpha s2-casein occurs under physiological conditions yet is prevented by its natural counterpart, alpha s1-casein. | Biochemistry 20080325 |
| Inhibition of LTP in vivo by beta-amyloid peptide in different conformational states. | Brain research 20080304 |
| Mixed macromolecular crowding inhibits amyloid formation of hen egg white lysozyme. | Biochimica et biophysica acta 20080301 |
| Amyloid-like fibrils in elastin-related polypeptides: structural characterization and elastic properties. | Biomacromolecules 20080301 |
| Specific fluorescent detection of fibrillar alpha-synuclein using mono- and trimethine cyanine dyes. | Bioorganic & medicinal chemistry 20080201 |
| Amyloid toxicity is independent of polypeptide sequence, length and chirality. | Journal of molecular biology 20080118 |
| Phospholipid interaction induces molecular-level polymorphism in apolipoprotein C-II amyloid fibrils via alternative assembly pathways. | Journal of molecular biology 20080104 |
| Thioflavin derivatives as markers for amyloid-beta fibrils: insights into structural features important for high-affinity binding. | ChemMedChem 20080101 |
| Congo red and thioflavin-T analogs detect Abeta oligomers. | Journal of neurochemistry 20080101 |
| Salvianolic acid B inhibits Abeta fibril formation and disaggregates preformed fibrils and protects against Abeta-induced cytotoxicty. | Neurochemistry international 20080101 |
| [Estimating of changes in the amyloid and prion content of yeast cells]. | Tsitologiia 20080101 |
| Contrasting in vivo effects of two peptide-based amyloid-beta protein aggregation inhibitors in a transgenic mouse model of amyloid deposition. | Cell transplantation 20080101 |
| Transthyretin protects against A-beta peptide toxicity by proteolytic cleavage of the peptide: a mechanism sensitive to the Kunitz protease inhibitor. | PloS one 20080101 |
| Whatever happened to Pittsburgh Compound-A? | Alzheimer disease and associated disorders 20080101 |
| Persisting atypical and cystic forms of Borrelia burgdorferi and local inflammation in Lyme neuroborreliosis. | Journal of neuroinflammation 20080101 |
| Nano-scale imaging and dynamics of amylin-membrane interactions and its implication in type II diabetes mellitus. | Methods in cell biology 20080101 |
| Anti-amyloidogenic activity of S-allyl-L-cysteine and its activity to destabilize Alzheimer's beta-amyloid fibrils in vitro. | Neuroscience letters 20071218 |
| Influence of phosphorus dendrimers on the aggregation of the prion peptide PrP 185-208. | Biochemical and biophysical research communications 20071207 |
| Differentiating Alzheimer disease-associated aggregates with small molecules. | Neurobiology of disease 20071201 |
| Promotion of insulin aggregation by protein disulfide isomerase. | Biochimica et biophysica acta 20071201 |
| Abeta 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner. | Antioxidants & redox signaling 20071201 |
| Amyloid adhesins are abundant in natural biofilms. | Environmental microbiology 20071201 |
| Monitoring the prevention of amyloid fibril formation by alpha-crystallin. Temperature dependence and the nature of the aggregating species. | The FEBS journal 20071201 |
| Evidence of fibril-like β-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloid. | Nature structural & molecular biology 20071201 |
| Sequence Determinants for Amyloid Fibrillogenesis of Human alpha-Synuclein. | Journal of molecular biology 20071123 |
| Design of mechanism-based inhibitors of transthyretin amyloidosis: studies with biphenyl ethers and new structural templates. | Journal of medicinal chemistry 20071115 |
| Evaluation of different culture conditions for high-level soluble expression of human cyclin A2 with pET vector in BL21 (DE3) and spectroscopic characterization of its inclusion body structure. | Protein expression and purification 20071101 |
| The role of the VQIVYK peptide in tau protein phosphorylation. | Journal of neurochemistry 20071101 |
| Novel chalcones as probes for in vivo imaging of beta-amyloid plaques in Alzheimer's brains. | Bioorganic & medicinal chemistry 20071101 |
| Apoptotic death induces Abeta production and fibril formation to a much larger extent than necrotic-like death in CGNs. | Journal of Alzheimer's disease : JAD 20071101 |
| Conversion of non-fibrillar beta-sheet oligomers into amyloid fibrils in Alzheimer's disease amyloid peptide aggregation. | Biochemical and biophysical research communications 20071005 |
| Polyfluorinated bis-styrylbenzene beta-amyloid plaque binding ligands. | Journal of medicinal chemistry 20071004 |
| Soluble oligomers from a non-disease related protein mimic Abeta-induced tau hyperphosphorylation and neurodegeneration. | Journal of neurochemistry 20071001 |
| Optimization of a polyglutamine aggregation inhibitor peptide (QBP1) using a thioflavin T fluorescence assay. | Assay and drug development technologies 20071001 |
| TgCRND8 amyloid precursor protein transgenic mice exhibit an altered gamma-secretase processing and an aggressive, additive amyloid pathology subject to immunotherapeutic modulation. | Biochemistry 20070911 |
| The active site cysteine of the proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase is essential in oxidative stress-induced aggregation and cell death. | The Journal of biological chemistry 20070907 |
| Phenylthiazolyl-hydrazide and its derivatives are potent inhibitors of tau aggregation and toxicity in vitro and in cells. | Biochemistry 20070904 |
| Binding mode of Thioflavin T in insulin amyloid fibrils. | Journal of structural biology 20070901 |
| Aggregation and fibrillation of bovine serum albumin. | Biochimica et biophysica acta 20070901 |
| Mapping the structural transition in an amyloidogenic apolipoprotein A-I. | Biochemistry 20070828 |
| Surface structure of amyloid-beta fibrils contributes to cytotoxicity. | Biochemistry 20070828 |
| Thioflavin T fluorescence anisotropy: an alternative technique for the study of amyloid aggregation. | Biochemical and biophysical research communications 20070817 |
| Conformational properties of aggregated polypeptides determine ClpB-dependence in the disaggregation process. | Journal of molecular biology 20070817 |
| Kinetic refolding barrier of guanidinium chloride denatured goose delta-crystallin leads to regular aggregate formation. | Biophysical journal 20070815 |
| Novel method for quantitative determination of amyloid fibrils of alpha-synuclein and amyloid beta/A4 protein by using resveratrol. | Analytical biochemistry 20070815 |
| Formation of toxic fibrils of Alzheimer's amyloid beta-protein-(1-40) by monosialoganglioside GM1, a neuronal membrane component. | Journal of molecular biology 20070810 |
| Role of a novel excipient poly(ethylene glycol)-b-poly(L-histidine) in retention of physical stability of insulin in aqueous solutions. | Pharmaceutical research 20070801 |
| Cyanine dye-protein interactions: looking for fluorescent probes for amyloid structures. | Journal of biochemical and biophysical methods 20070801 |
| Cytotoxicity of insulin within its self-assembly and amyloidogenic pathways. | Journal of molecular biology 20070706 |
| Analytical method for beta-amyloid fibrils using CE-laser induced fluorescence and its application to screening for inhibitors of beta-amyloid protein aggregation. | Analytical chemistry 20070701 |
| Hyper-homocysteinemia alters amyloid peptide-clusterin interactions and neuroglial network morphology and function in the caudate after intrastriatal injection of amyloid peptides. | Current Alzheimer research 20070701 |
| High throughput screening for small molecule inhibitors of heparin-induced tau fibril formation. | Biochemical and biophysical research communications 20070622 |
| Glucagon amyloid-like fibril morphology is selected via morphology-dependent growth inhibition. | Biochemistry 20070619 |
| Preferential association of serum amyloid P component with fibrillar deposits in familial British and Danish dementias: similarities with Alzheimer's disease. | Journal of the neurological sciences 20070615 |
| Computational study of thioflavin T torsional relaxation in the excited state. | The journal of physical chemistry. A 20070607 |
| Study on the binding of Thioflavin T to beta-sheet-rich and non-beta-sheet cavities. | Journal of structural biology 20070601 |
| Anti-fibrillogenic and fibril-destabilizing activity of nicotine in vitro: implications for the prevention and therapeutics of Lewy body diseases. | Experimental neurology 20070601 |
| Consequential alterations in haemoglobin structure upon glycation with fructose: prevention by acetylsalicylic acid. | Journal of biochemistry 20070601 |
| Mulberry leaf extract prevents amyloid beta-peptide fibril formation and neurotoxicity. | Neuroreport 20070528 |
| Aggregation of lysozyme and of poly(ethylene glycol)-modified lysozyme after adsorption to silica. | Colloids and surfaces. B, Biointerfaces 20070515 |
| Effects of oxidation on the structure and stability of human low-density lipoprotein. | Biochemistry 20070515 |
| Cloning and expression of human islet amyloid polypeptide in cultured cells. | Biochemical and biophysical research communications 20070511 |
| Hsp40 interacts directly with the native state of the yeast prion protein Ure2 and inhibits formation of amyloid-like fibrils. | The Journal of biological chemistry 20070420 |
| Thioflavin T and birefringence assays to determine the conversion of proteins into fibrils. | Langmuir : the ACS journal of surfaces and colloids 20070410 |
| Alternative membrane protein conformations in alcohols. | Biochemistry 20070410 |
| Spectral properties of thioflavin T in solvents with different dielectric properties and in a fibril-incorporated form. | Journal of proteome research 20070401 |
| Trehalose effects on alpha-crystallin aggregates. | Biochemical and biophysical research communications 20070323 |
| Linear quantitation of Abeta aggregation using Thioflavin T: reduction in fibril formation by colostrinin. | Journal of neuroscience methods 20070315 |
| A structural core within apolipoprotein C-II amyloid fibrils identified using hydrogen exchange and proteolysis. | Journal of molecular biology 20070309 |
| Bis-styrylpyridine and bis-styrylbenzene derivatives as inhibitors for Abeta fibril formation. | Bioorganic & medicinal chemistry letters 20070301 |
| [Molecular imaging of beta-amyloid plaques in the brain]. | Brain and nerve = Shinkei kenkyu no shinpo 20070301 |
| Spider silk and amyloid fibrils: a structural comparison. | Macromolecular bioscience 20070212 |
| Kinetics of different processes in human insulin amyloid formation. | Journal of molecular biology 20070209 |
| Characterisation and physical stability of PEGylated glucagon. | International journal of pharmaceutics 20070207 |
| Detection and characterization of protein aggregates by fluorescence microscopy. | International journal of pharmaceutics 20070201 |
| Cerebrospinal fluid of Alzheimer's disease and dementia with Lewy bodies patients enhances alpha-synuclein fibril formation in vitro. | Experimental neurology 20070201 |
| Kinetic studies of protein L aggregation and disaggregation. | Biophysical chemistry 20070201 |
| Vitamin A potently destabilizes preformed alpha-synuclein fibrils in vitro: implications for Lewy body diseases. | Neurobiology of disease 20070201 |
| Formation of amyloid-like fibrils by ovalbumin and related proteins under conditions relevant to food processing. | Journal of agricultural and food chemistry 20070124 |
| Identification of an amyloidogenic region on keratoepithelin via synthetic peptides. | FEBS letters 20070123 |
| Amyloid fibrils formation and amorphous aggregation in concanavalin A. | Biophysical chemistry 20070101 |
| pH-dependent self-assembly of polyalanine peptides. | Biophysical journal 20070101 |
| Evidence for fibril-like structure in bovine casein micelles. | Journal of dairy science 20070101 |
| Cystatin C reduces the in vitro formation of soluble Abeta1-42 oligomers and protofibrils. | Scandinavian journal of clinical and laboratory investigation 20070101 |
| The effects of various membrane physical-chemical properties on the aggregation kinetics of insulin. | Chemistry and physics of lipids 20070101 |
| Protection by EGb 761 against beta-amyloid-induced neurotoxicity: involvement of NF-kappaB, SIRT1, and MAPKs pathways and inhibition of amyloid fibril formation. | Free radical biology & medicine 20061215 |
| N- and C-terminal hydrophobic patches are involved in fibrillation of glucagon. | Biochemistry 20061205 |
| Inhibition of human IAPP fibril formation does not prevent beta-cell death: evidence for distinct actions of oligomers and fibrils of human IAPP. | American journal of physiology. Endocrinology and metabolism 20061201 |
| Potential inplications of endogenous aldehydes in beta-amyloid misfolding, oligomerization and fibrillogenesis. | Journal of neurochemistry 20061201 |
| The early stages of amyloid formation: biophysical and structural characterization of human calcitonin pre-fibrillar assemblies. | Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20061201 |
| Molecular heterosis of prion protein beta-oligomers. A potential mechanism of human resistance to disease. | The Journal of biological chemistry 20061110 |
| Further evidence of local ganglioside-dependent amyloid beta-protein assembly in brain. | Neuroreport 20061106 |
| Proline and glycine control protein self-organization into elastomeric or amyloid fibrils. | Structure (London, England : 1993) 20061101 |
| Age- and transgene-related changes in regional cerebral metabolism in PSAPP mice. | Brain research 20061020 |
| On the seeding and oligomerization of pGlu-amyloid peptides (in vitro). | Biochemistry 20061017 |
| Oligo(ethylene glycol) derivatives of thioflavin T as inhibitors of protein-amyloid interactions. | Chembiochem : a European journal of chemical biology 20061001 |
| Amyloid formation in denatured single-mutant lysozymes where residual structures are modulated. | Protein science : a publication of the Protein Society 20061001 |
| Viral-induced inflammation is accompanied by beta-amyloid plaque reduction in brains of amyloid precursor protein transgenic Tg2576 mice. | The European journal of neuroscience 20061001 |
| Oleic acid inhibits amyloid formation of the intermediate of alpha-lactalbumin at moderately acidic pH. | Journal of molecular biology 20060929 |
| Osmolyte trimethylamine N-oxide converts recombinant alpha-helical prion protein to its soluble beta-structured form at high temperature. | Journal of molecular biology 20060929 |
| Phage display affords peptides that modulate beta-amyloid aggregation. | Journal of the American Chemical Society 20060913 |
| Inhibitor discovery targeting the intermediate structure of beta-amyloid peptide on the conformational transition pathway: implications in the aggregation mechanism of beta-amyloid peptide. | Biochemistry 20060912 |
| Cooexpression of FTDP-17 tau and GSK-3beta in transgenic mice induce tau polymerization and neurodegeneration. | Neurobiology of aging 20060901 |
| Characterisation of the binding of amyloid imaging tracers to rodent Abeta fibrils and rodent-human Abeta co-polymers. | Biochemical and biophysical research communications 20060901 |
| Amino-terminal domain stability mediates apolipoprotein E aggregation into neurotoxic fibrils. | Journal of molecular biology 20060901 |
| High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation. | The FEBS journal 20060901 |
| Uncaria rhynchophylla, a Chinese medicinal herb, has potent antiaggregation effects on Alzheimer's beta-amyloid proteins. | Journal of neuroscience research 20060801 |
| Memory-related deficits following selective hippocampal expression of Swedish mutation amyloid precursor protein in the rat. | Experimental neurology 20060801 |
| Characteristics of the binding of thioflavin S to tau paired helical filaments. | Journal of Alzheimer's disease : JAD 20060801 |
| Cu(II) induces small-size aggregates with amyloid characteristics in two alleles of recombinant ovine prion proteins. | Biochimica et biophysica acta 20060701 |
| Molecular interactions of dendrimers with amyloid peptides: pH dependence. | Biomacromolecules 20060701 |
| Lipophilic analogs of thioflavin S as novel amyloid-imaging agents. | Current Alzheimer research 20060701 |
| The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step. | The Journal of biological chemistry 20060623 |
| Collagen plays an active role in the aggregation of beta2-microglobulin under physiopathological conditions of dialysis-related amyloidosis. | The Journal of biological chemistry 20060616 |
| Kinetics of insulin aggregation: disentanglement of amyloid fibrillation from large-size cluster formation. | Biophysical journal 20060615 |
| Methods for enhancing the accuracy and reproducibility of Congo red and thioflavin T assays. | Analytical biochemistry 20060601 |
| Frontotemporal dementia: clinicopathological correlations. | Annals of neurology 20060601 |
| Proteasomal inhibition hypersensitizes differentiated neuroblastoma cells to oxidative damage. | Neuroscience letters 20060515 |
| Fluorescence-coupled CD conformational monitoring of filament formation of tau microtubule-binding repeat domain. | Biochemical and biophysical research communications 20060512 |
| alphaB-crystallin maintains skeletal muscle myosin enzymatic activity and prevents its aggregation under heat-shock stress. | Journal of molecular biology 20060505 |
| Mechanism of thioflavin T accumulation inside cells overexpressing P-glycoprotein or multidrug resistance-associated protein: role of lipophilicity and positive charge. | Biochemical and biophysical research communications 20060505 |
| Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42. | Biochemistry 20060502 |
| Intermediate amyloid oligomers of lysozyme: Is their cytotoxicity a particular case or general rule for amyloid? | Biochemistry. Biokhimiia 20060501 |
| Peripheral region for core cross-beta plays important role in amyloidogenicity. | Biochemical and biophysical research communications 20060414 |
| Assessing the role of aromatic residues in the amyloid aggregation of human muscle acylphosphatase. | Protein science : a publication of the Protein Society 20060401 |
| Role of N-terminal familial mutations in prion protein fibrillization and prion amyloid propagation in vitro. | The Journal of biological chemistry 20060324 |
| Alpha-lipoic acid exhibits anti-amyloidogenicity for beta-amyloid fibrils in vitro. | Biochemical and biophysical research communications 20060324 |
| Structural basis of the cofactor function of denatured albumin in plasminogen activation by tissue-type plasminogen activator. | Biochemical and biophysical research communications 20060317 |
| [Dynamics of in vitro amyloid fiber formation of yeast prion protein Sup35NM]. | Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20060301 |
| Formation of tau inclusions in knock-in mice with familial Alzheimer disease (FAD) mutation of presenilin 1 (PS1). | The Journal of biological chemistry 20060224 |
| Nonfibrous beta-structured aggregation of an Abeta model peptide (Ad-2alpha) on GM1/DPPC mixed monolayer surfaces. | Journal of colloid and interface science 20060215 |
| Inhibiting protein-amyloid interactions with small molecules: a surface chemistry approach. | Bioorganic & medicinal chemistry letters 20060215 |
| Inhibitory effect of minocycline on amyloid beta fibril formation and human microglial activation. | Glia 20060201 |
| Mutagenesis of the central hydrophobic cluster in Abeta42 Alzheimer's peptide. Side-chain properties correlate with aggregation propensities. | The FEBS journal 20060201 |
| Inducible expression of Tau repeat domain in cell models of tauopathy: aggregation is toxic to cells but can be reversed by inhibitor drugs. | The Journal of biological chemistry 20060113 |
| Scanning cysteine mutagenesis analysis of Abeta-(1-40) amyloid fibrils. | The Journal of biological chemistry 20060113 |
| Deficiency of disulfide bonds facilitating fibrillogenesis of endostatin. | The Journal of biological chemistry 20060113 |
| Influence of heparin and dendrimers on the aggregation of two amyloid peptides related to Alzheimer's and prion diseases. | Biochemical and biophysical research communications 20060113 |
| Functional amyloid formation within mammalian tissue. | PLoS biology 20060101 |
| Structure of amyloid beta fragments in aqueous environments. | The FEBS journal 20060101 |
| Thioflavins released from nanoparticles target fibrillar amyloid beta in the hippocampus of APP/PS1 transgenic mice. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20060101 |
| Shear flow induces amyloid fibril formation. | Biomacromolecules 20060101 |
| Conformation dependent pro-apoptotic activity of the recombinant human prion protein fragment 90-231. | International journal of immunopathology and pharmacology 20060101 |
| Direct observation of amyloid growth monitored by total internal reflection fluorescence microscopy. | Methods in enzymology 20060101 |
| Sedimentation velocity analysis of amyloid oligomers and fibrils. | Methods in enzymology 20060101 |
| Conformation-dependent anti-amyloid oligomer antibodies. | Methods in enzymology 20060101 |
| Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease. | The Journal of biological chemistry 20051230 |
| Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice. | The Journal of biological chemistry 20051230 |
| Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans. | The Journal of biological chemistry 20051230 |
| Early events in the fibrillation of monomeric insulin. | The Journal of biological chemistry 20051230 |
| Amyloid fibril formation by bovine milk kappa-casein and its inhibition by the molecular chaperones alphaS- and beta-casein. | Biochemistry 20051227 |
| The role of His-18 in amyloid formation by human islet amyloid polypeptide. | Biochemistry 20051213 |
| Chiral bias of amyloid fibrils revealed by the twisted conformation of Thioflavin T: an induced circular dichroism/DFT study. | FEBS letters 20051205 |
| Amyloid fibril formation of alpha-synuclein is accelerated by preformed amyloid seeds of other proteins: implications for the mechanism of transmissible conformational diseases. | The Journal of biological chemistry 20051118 |
| Radioiodinated flavones for in vivo imaging of beta-amyloid plaques in the brain. | Journal of medicinal chemistry 20051117 |
| Structural studies reveal that the diverse morphology of beta(2)-microglobulin aggregates is a reflection of different molecular architectures. | Biochimica et biophysica acta 20051110 |
| The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy. | Journal of neurochemistry 20051101 |
| Cerebrospinal fluid of Alzheimer patients promotes beta-amyloid fibril formation in vitro. | Neurobiology of disease 20051101 |
| Synthesis of 6-[2-(benzoxazol-2-ylmethylamino)ethoxy]-1-alkyl-1H-indole-2-carboxylic acid and inhibitory activity on beta-amyloid aggregation. | Archives of pharmacal research 20051101 |
| Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia. | The Journal of biological chemistry 20051028 |
| In vivo magnetic resonance microimaging of individual amyloid plaques in Alzheimer's transgenic mice. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20051026 |
| Characterization of oligomeric intermediates in alpha-synuclein fibrillation: FRET studies of Y125W/Y133F/Y136F alpha-synuclein. | Journal of molecular biology 20051021 |
| Controlling {beta}-amyloid oligomerization by the use of naphthalene sulfonates: trapping low molecular weight oligomeric species. | The Journal of biological chemistry 20051014 |
| Sequence determinants of enhanced amyloidogenicity of Alzheimer A{beta}42 peptide relative to A{beta}40. | The Journal of biological chemistry 20051014 |
| Haploinsufficiency for trkB and trkC receptors induces cell loss and accumulation of alpha-synuclein in the substantia nigra. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051001 |
| Main-chain dominated amyloid structures demonstrated by the effect of high pressure. | Journal of molecular biology 20050930 |
| Helix-turn-helix peptides that form alpha-helical fibrils: turn sequences drive fibril structure. | Biochemistry 20050927 |
| Thermodynamics of A beta(1-40) amyloid fibril elongation. | Biochemistry 20050927 |
| Ultrasonication-induced amyloid fibril formation of beta2-microglobulin. | The Journal of biological chemistry 20050923 |
| Effects of the sequence and size of non-polar residues on self-assembly of amphiphilic peptides. | International journal of biological macromolecules 20050915 |
| Amyloid-like fibril formation of co-chaperonin GroES: nucleation and extension prefer different degrees of molecular compactness. | Journal of molecular biology 20050902 |
| Mechanism of thioflavin T binding to amyloid fibrils. | Journal of structural biology 20050901 |
| Cyanine dye N744 inhibits tau fibrillization by blocking filament extension: implications for the treatment of tauopathic neurodegenerative diseases. | Biochemistry 20050802 |
| Dopamine promotes alpha-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050801 |
| Aluminum-triggered structural modifications and aggregation of beta-amyloids. | Cellular and molecular life sciences : CMLS 20050801 |
| Influence of the N-terminal domain on the aggregation properties of the prion protein. | Protein science : a publication of the Protein Society 20050801 |
| Thermostable direct hemolysin of Vibrio parahaemolyticus is a bacterial reversible amyloid toxin. | Biochemistry 20050726 |
| Abeta42 is essential for parenchymal and vascular amyloid deposition in mice. | Neuron 20050721 |
| On the chaperonin activity of GroEL at heat-shock temperature. | The international journal of biochemistry & cell biology 20050701 |
| Water-soluble hybrid nanoclusters with extra bright and photostable emissions: a new tool for biological imaging. | Biophysical journal 20050701 |
| Transformation of diffuse beta-amyloid precursor protein and beta-amyloid deposits to plaques in the thalamus after transient occlusion of the middle cerebral artery in rats. | Stroke 20050701 |
| The aggregation kinetics of Alzheimer's beta-amyloid peptide is controlled by stochastic nucleation. | Protein science : a publication of the Protein Society 20050701 |
| Inducible neuronal expression of transgenic TGF-beta1 in vivo: dissection of short-term and long-term effects. | The European journal of neuroscience 20050701 |
| Ethanol-perturbed amyloidogenic self-assembly of insulin: looking for origins of amyloid strains. | Biochemistry 20050628 |
| Oxidation of low-density lipoproteins induces amyloid-like structures that are recognized by macrophages. | Biochemistry 20050628 |
| Delineation of positron emission tomography imaging agent binding sites on beta-amyloid peptide fibrils. | The Journal of biological chemistry 20050624 |
| Amidation and structure relaxation abolish the neurotoxicity of the prion peptide PrP106-126 in vivo and in vitro. | The Journal of biological chemistry 20050617 |
| Protective effect of donepezil against Abeta(1-40) neurotoxicity in rat septal neurons. | Brain research 20050614 |
| Higher-order molecular packing in amyloid-like fibrils constructed with linear arrangements of hydrophobic and hydrogen-bonding side-chains. | Journal of molecular biology 20050513 |
| Activity, folding, misfolding, and aggregation in vitro of the naturally occurring human tissue factor mutant R200W. | Biochemistry 20050510 |
| The SC3 hydrophobin self-assembles into a membrane with distinct mass transfer properties. | Biophysical journal 20050501 |
| Collagenous Alzheimer amyloid plaque component assembles amyloid fibrils into protease resistant aggregates. | The FEBS journal 20050501 |
| Heat shock protein 70 inhibits alpha-synuclein fibril formation via preferential binding to prefibrillar species. | The Journal of biological chemistry 20050415 |
| Efficient radiosynthesis of carbon-11 labelled uncharged Thioflavin T derivatives using [11C]methyl triflate for beta-amyloid imaging in Alzheimer's Disease with PET. | Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20050401 |
| Development of novel amyloid imaging agents based upon thioflavin S. | Current Alzheimer research 20050401 |
| Unfolding, aggregation, and seeded amyloid formation of lysine-58-cleaved beta 2-microglobulin. | Biochemistry 20050322 |
| Investigating the effects of mutations on protein aggregation in the cell. | The Journal of biological chemistry 20050318 |
| CLAC binds to amyloid beta peptides through the positively charged amino acid cluster within the collagenous domain 1 and inhibits formation of amyloid fibrils. | The Journal of biological chemistry 20050304 |
| Evidence for the presence of three distinct binding sites for the thioflavin T class of Alzheimer's disease PET imaging agents on beta-amyloid peptide fibrils. | The Journal of biological chemistry 20050304 |
| Multiple ligand binding sites on A beta(1-40) fibrils. | Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20050301 |
| Fibrillogenesis of apomyoglobin facilitated by aggregation sequence of yeast Sup35 in various regions. | FEBS letters 20050227 |
| Role of amyloid type cross beta-structure in the formation of soluble aggregate and gel in heat-induced ovalbumin. | Journal of agricultural and food chemistry 20050223 |
| Single-site mutations in a hyperthermophilic variant of the B1 domain of protein G result in self-assembled oligomers. | Biochemistry 20050222 |
| Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo. | The Journal of biological chemistry 20050218 |
| Amyloid-beta protofibrils differ from amyloid-beta aggregates induced in dilute hexafluoroisopropanol in stability and morphology. | The Journal of biological chemistry 20050128 |
| The binding of thioflavin-T to amyloid fibrils: localisation and implications. | Journal of structural biology 20050101 |
| Purification of recombinant tau protein and preparation of Alzheimer-paired helical filaments in vitro. | Methods in molecular biology (Clifton, N.J.) 20050101 |
| Histological staining of amyloid-beta in mouse brains. | Methods in molecular biology (Clifton, N.J.) 20050101 |
| Circular dichroism and aggregation studies of amyloid beta (11-8) fragment and its variants. | Acta biochimica Polonica 20050101 |
| Protective effect of zinc on amyloid-beta 25-35 and 1-40 mediated toxicity. | Neurotoxicity research 20050101 |
| Glycogen synthase kinase 3 beta induces caspase-cleaved tau aggregation in situ. | The Journal of biological chemistry 20041224 |
| An intersheet packing interaction in A beta fibrils mapped by disulfide cross-linking. | Biochemistry 20041214 |
| Unraveling the amyloid associated with human medullary thyroid carcinoma. | Endocrinology 20041201 |
| Inhibition of amyloid fibrillogenesis and toxicity by a peptide chaperone. | Molecular and cellular biochemistry 20041201 |
| alpha-synuclein is required for the fibrillar nature of ubiquitinated inclusions induced by proteasomal inhibition in primary neurons. | The Journal of biological chemistry 20041105 |
| Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases. | The Journal of biological chemistry 20041105 |
| A designed protein interface that blocks fibril formation. | Journal of the American Chemical Society 20041103 |
| Anionic contribution for fibrous maturation of protofibrillar assemblies of the human tau repeat domain in a fluoroalcohol solution. | Biochemistry 20041026 |
| An in vitro screening assay based on synthetic prion protein peptides for identification of fibril-interfering compounds. | Analytical biochemistry 20041015 |
| Vitamin A exhibits potent antiamyloidogenic and fibril-destabilizing effects in vitro. | Experimental neurology 20041001 |
| Mechanism of prion propagation: amyloid growth occurs by monomer addition. | PLoS biology 20041001 |
| Apolipoprotein is required for the formation of filamentous amyloid, but not for amorphous Abeta deposition, in an AbetaPP/PS double transgenic mouse model of Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20041001 |
| Amyloid fibril formation by a partially structured intermediate state of alpha-chymotrypsin. | Journal of molecular biology 20040903 |
| Nordihydroguaiaretic acid does not disaggregate beta-amyloid(1-40) protofibrils but does inhibit growth arising from direct protofibril association. | Molecular pharmacology 20040901 |
| Morphological characterization of Thioflavin-S-positive amyloid plaques in transgenic Alzheimer mice and effect of passive Abeta immunotherapy on their clearance. | The American journal of pathology 20040901 |
| Targeting the neurotoxic species in Alzheimer's disease: inhibitors of Abeta oligomerization. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040901 |
| Differential expression of cholesterol hydroxylases in Alzheimer's disease. | The Journal of biological chemistry 20040813 |
| Inflammation occurs early during the Abeta deposition process in TgCRND8 mice. | Neurobiology of aging 20040801 |
| Walnut extract inhibits the fibrillization of amyloid beta-protein, and also defibrillizes its preformed fibrils. | Current Alzheimer research 20040801 |
| Mostly separate distributions of CLAC- versus Abeta40- or thioflavin S-reactivities in senile plaques reveal two distinct subpopulations of beta-amyloid deposits. | The American journal of pathology 20040701 |
| The human serpin proteinase inhibitor-9 self-associates at physiological temperatures. | Protein science : a publication of the Protein Society 20040701 |
| The flavonoid baicalein inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils. | The Journal of biological chemistry 20040625 |
| Transthyretin aggregation under partially denaturing conditions is a downhill polymerization. | Biochemistry 20040615 |
| Single chain variable fragments against beta-amyloid (Abeta) can inhibit Abeta aggregation and prevent abeta-induced neurotoxicity. | Biochemistry 20040608 |
| Annular oligomeric amyloid intermediates observed by in situ atomic force microscopy. | The Journal of biological chemistry 20040604 |
| Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuum. | Annals of neurology 20040601 |
| NMR of alpha-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation. | The EMBO journal 20040519 |
| A seed for Alzheimer amyloid in the brain. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040519 |
| Early-onset and robust cerebral microvascular accumulation of amyloid beta-protein in transgenic mice expressing low levels of a vasculotropic Dutch/Iowa mutant form of amyloid beta-protein precursor. | The Journal of biological chemistry 20040507 |
| Proteins can convert to beta-sheet in single crystals. | Protein science : a publication of the Protein Society 20040501 |
| Seeding specificity in amyloid growth induced by heterologous fibrils. | The Journal of biological chemistry 20040423 |
| Molecular basis of barriers for interspecies transmissibility of mammalian prions. | Molecular cell 20040409 |
| The HPV16 E7 viral oncoprotein self-assembles into defined spherical oligomers. | Biochemistry 20040330 |
| Fibrillogenesis and cytotoxic activity of the amyloid-forming apomyoglobin mutant W7FW14F. | The Journal of biological chemistry 20040326 |
| Inhibiting aggregation of alpha-synuclein with human single chain antibody fragments. | Biochemistry 20040316 |
| Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro. | Journal of neuroscience research 20040315 |
| Pseudophosphorylation of tau protein alters its ability for self-aggregation. | Journal of neurochemistry 20040301 |
| Evidence for an intermediate in tau filament formation. | Biochemistry 20040217 |
| The human amyloid-beta precursor protein770 mutation V717F generates peptides longer than amyloid-beta-(40-42) and flocculent amyloid aggregates. | The Journal of biological chemistry 20040213 |
| Neuronal localization of C1q in preclinical Alzheimer's disease. | Neurobiology of disease 20040201 |
| An engineered PrPsc-like molecule from the chimera of mammalian prion protein and yeast Ure2p prion-inducing domain. | Acta biochimica et biophysica Sinica 20040201 |
| Amyloid nucleation and hierarchical assembly of Ure2p fibrils. Role of asparagine/glutamine repeat and nonrepeat regions of the prion domains. | The Journal of biological chemistry 20040130 |
| Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation. | The Journal of biological chemistry 20040130 |
| Effect of different anti-Abeta antibodies on Abeta fibrillogenesis as assessed by atomic force microscopy. | Journal of molecular biology 20040123 |
| In vivo labeling of amyloid with BF-108. | Neuroscience research 20040101 |
| Imaging beta-amyloid plaques and neurofibrillary tangles in the aging human brain. | Current pharmaceutical design 20040101 |
| Cholesterol, copper, and accumulation of thioflavine S-reactive Alzheimer's-like amyloid beta in rabbit brain. | Journal of molecular neuroscience : MN 20040101 |
| Neuronal fibrillogenesis: amyloid fibrils from primary neuronal cultures impair long-term memory in the crab Chasmagnathus. | Behavioural brain research 20031217 |
| [Therapeutics for prion diseases]. | Rinsho shinkeigaku = Clinical neurology 20031101 |
| Glycation induces formation of amyloid cross-beta structure in albumin. | The Journal of biological chemistry 20031024 |
| Partially folded intermediates in insulin fibrillation. | Biochemistry 20031007 |
| Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease. | Journal of neurochemistry 20031001 |
| The role of protein stability, solubility, and net charge in amyloid fibril formation. | Protein science : a publication of the Protein Society 20031001 |
| Proteasome inhibition stabilizes tau inclusions in oligodendroglial cells that occur after treatment with okadaic acid. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20031001 |
| Nitration of tau protein is linked to neurodegeneration in tauopathies. | The American journal of pathology 20030901 |
| An amyloid-like C-terminal domain of thrombospondin-1 displays CD47 agonist activity requiring both VVM motifs. | Biochemistry 20030826 |
| Hydrogen exchange-mass spectrometry analysis of beta-amyloid peptide structure. | Biochemistry 20030812 |
| A peptide motif consisting of glycine, alanine, and valine is required for the fibrillization and cytotoxicity of human alpha-synuclein. | Biochemistry 20030729 |
| A systematic investigation into the effect of protein destabilisation on beta 2-microglobulin amyloid formation. | Journal of molecular biology 20030725 |
| Amyloid protofilaments from the calcium-binding protein equine lysozyme: formation of ring and linear structures depends on pH and metal ion concentration. | Journal of molecular biology 20030718 |
| Structural transformations of oligomeric intermediates in the fibrillation of the immunoglobulin light chain LEN. | Biochemistry 20030708 |
| Specific compositions of amyloid-beta peptides as the determinant of toxic beta-aggregation. | The Journal of biological chemistry 20030627 |
| Analysis of yeast prion aggregates with amyloid-staining compound in vivo. | Cell structure and function 20030601 |
| Amyloid-like fibril formation in an all beta-barrel protein. Partially structured intermediate state(s) is a precursor for fibril formation. | The Journal of biological chemistry 20030516 |
| Unmasking tandem site interaction in human acetylcholinesterase. Substrate activation with a cationic acetanilide substrate. | Biochemistry 20030513 |
| Direct observation of amyloid fibril growth monitored by thioflavin T fluorescence. | The Journal of biological chemistry 20030509 |
| Direct determination of the proportion of intra- and extra-cellular neocortical neurofibrillary tangles in Alzheimer's disease. | Brain research 20030502 |
| Intracranially administered anti-Abeta antibodies reduce beta-amyloid deposition by mechanisms both independent of and associated with microglial activation. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030501 |
| Environmental influences on bovine kappa-casein: reduction and conversion to fibrillar (amyloid) structures. | Journal of protein chemistry 20030401 |
| X-ray absorption spectroscopy reveals a substantial increase of sulfur oxidation in transthyretin (TTR) upon fibrillization. | The Journal of biological chemistry 20030328 |
| Reversible amyloid formation by the p53 tetramerization domain and a cancer-associated mutant. | Journal of molecular biology 20030328 |
| In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030315 |
| Conformational behavior and aggregation of alpha-synuclein in organic solvents: modeling the effects of membranes. | Biochemistry 20030311 |
| Mutations in the B1 domain of protein G that delay the onset of amyloid fibril formation in vitro. | Protein science : a publication of the Protein Society 20030301 |
| Electron microscopic analysis of nanoparticles delivering thioflavin-T after intrahippocampal injection in mouse: implications for targeting beta-amyloid in Alzheimer's disease. | Neuroscience letters 20030227 |
| In vivo multiphoton imaging of a transgenic mouse model of Alzheimer disease reveals marked thioflavine-S-associated alterations in neurite trajectories. | Journal of neuropathology and experimental neurology 20030201 |
| Conformational restriction via cyclization in beta-amyloid peptide Abeta(1-28) leads to an inhibitor of Abeta(1-28) amyloidogenesis and cytotoxicity. | Chemistry & biology 20030201 |
| Probing the role of backbone hydrogen bonding in beta-amyloid fibrils with inhibitor peptides containing ester bonds at alternate positions. | Biochemistry 20030121 |
| Experimental evidence for multiple assembled states of Sc3 from Schizophyllum commune. | Biomacromolecules 20030101 |
| Characterization of radioiodinated ligand binding to amyloid beta plaques. | Journal of molecular neuroscience : MN 20030101 |
| Neuroprotection against Abeta and glutamate toxicity by melatonin: are GABA receptors involved? | Neurotoxicity research 20030101 |
| Oxidation-induced misfolding and aggregation of superoxide dismutase and its implications for amyotrophic lateral sclerosis. | The Journal of biological chemistry 20021206 |
| Acid Denaturation of alpha1-antitrypsin: characterization of a novel mechanism of serpin polymerization. | Journal of molecular biology 20021206 |
| Molecular imaging of amyloid beta peptides in mouse brain sections using mass spectrometry. | Analytical biochemistry 20021201 |
| IMPY: an improved thioflavin-T derivative for in vivo labeling of beta-amyloid plaques. | Brain research 20021129 |
| Amyloid fibril formation by a synthetic peptide from a region of human acetylcholinesterase that is homologous to the Alzheimer's amyloid-beta peptide. | Biochemistry 20021119 |
| New class of inhibitors of amyloid-beta fibril formation. Implications for the mechanism of pathogenesis in Alzheimer's disease. | The Journal of biological chemistry 20021108 |
| Synthesis of (-)-5,8-dihydroxy-3R-methyl-2R-(dipropylamino)-1,2,3,4-tetrahydronaphthalene: an inhibitor of beta-amyloid(1-42) aggregation. | Bioorganic & medicinal chemistry 20021101 |
| BIGH3 (TGFBI) Arg124 mutations influence the amyloid conversion of related peptides in vitro. | European journal of biochemistry 20021101 |
| Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20021101 |
| Molecular targeting of Alzheimer's amyloid plaques for contrast-enhanced magnetic resonance imaging. | Neurobiology of disease 20021101 |
| Circumvention of chaperone requirement for aggregate formation of a short polyglutamine tract by the co-expression of a long polyglutamine tract. | The Journal of biological chemistry 20021004 |
| Aggregation and self-assembly of hydrophobins from Trichoderma reesei: low-resolution structural models. | Biophysical journal 20021001 |
| Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020915 |
| Dependence of alpha-synuclein aggregate morphology on solution conditions. | Journal of molecular biology 20020913 |
| DNA-induced partial unfolding of prion protein leads to its polymerisation to amyloid. | Journal of molecular biology 20020906 |
| Amyloid formation in rat transthyretin: effect of oxidative stress. | Clinica chimica acta; international journal of clinical chemistry 20020901 |
| Microvascular reperfusion injury: rapid expansion of anatomic no reflow during reperfusion in the rabbit. | American journal of physiology. Heart and circulatory physiology 20020901 |
| Beta-amyloid plaques in a model for sporadic Alzheimer's disease based on transgenic anti-nerve growth factor antibodies. | Molecular and cellular neurosciences 20020901 |
| A novel compound, RS-1178, specifically inhibits neuronal cell death mediated by beta-amyloid-induced macrophage activation in vitro. | Brain research 20020816 |
| Kinetics and energetics of assembly, nucleation, and growth of aggregates and fibrils for an amyloidogenic protein. Insights into transition states from pressure, temperature, and co-solute studies. | The Journal of biological chemistry 20020726 |
| Amyloid architecture: complementary assembly of heterogeneous combinations of three or four peptides into amyloid fibrils. | Chembiochem : a European journal of chemical biology 20020702 |
| Concurrence of alpha-synuclein and tau brain pathology in the Contursi kindred. | Acta neuropathologica 20020701 |
| Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site. | Neurobiology of disease 20020701 |
| The ceruloplasmin and hydrogen peroxide system induces alpha-synuclein aggregation in vitro. | Biochimie 20020701 |
| Conformation of beta 2-microglobulin amyloid fibrils analyzed by reduction of the disulfide bond. | The Journal of biological chemistry 20020614 |
| Amyloid-like features of polyglutamine aggregates and their assembly kinetics. | Biochemistry 20020611 |
| Substitution of isoleucine-31 by helical-breaking proline abolishes oxidative stress and neurotoxic properties of Alzheimer's amyloid beta-peptide. | Free radical biology & medicine 20020601 |
| Suppression of apolipoprotein C-II amyloid formation by the extracellular chaperone, clusterin. | European journal of biochemistry 20020601 |
| Synthesis, aggregation, neurotoxicity, and secondary structure of various A beta 1-42 mutants of familial Alzheimer's disease at positions 21-23. | Biochemical and biophysical research communications 20020531 |
| A protein sequence that can encode native structure by disfavoring alternate conformations. | Nature structural biology 20020501 |
| Nordihydroguaiaretic acid potently breaks down pre-formed Alzheimer's beta-amyloid fibrils in vitro. | Journal of neurochemistry 20020501 |
| Amyloid fibrils from the mammalian protein prothymosin alpha. | FEBS letters 20020424 |
| Disassembly of amyloid beta-protein fibril by basement membrane components. | Life sciences 20020405 |
| Prion peptide 106-126 as a model for prion replication and neurotoxicity. | Frontiers in bioscience : a journal and virtual library 20020401 |
| Comparative analysis of an improved thioflavin-s stain, Gallyas silver stain, and immunohistochemistry for neurofibrillary tangle demonstration on the same sections. | The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20020401 |
| A designed system for assessing how sequence affects alpha to beta conformational transitions in proteins. | The Journal of biological chemistry 20020322 |
| Macromolecular crowding accelerates amyloid formation by human apolipoprotein C-II. | The Journal of biological chemistry 20020308 |
| Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta. | Journal of neuropathology and experimental neurology 20020301 |
| Type IV collagen prevents amyloid beta-protein fibril formation. | Life sciences 20020215 |
| A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain. | Bioorganic & medicinal chemistry letters 20020211 |
| Kinetic partitioning of protein folding and aggregation. | Nature structural biology 20020201 |
| Human stefin B readily forms amyloid fibrils in vitro. | Biochimica et biophysica acta 20020131 |
| Investigation of a peptide responsible for amyloid fibril formation of beta 2-microglobulin by achromobacter protease I. | The Journal of biological chemistry 20020111 |
| Inhibitors of fibril formation and cytotoxicity of beta-amyloid peptide composed of KLVFF recognition element and flexible hydrophilic disrupting element. | Biochemical and biophysical research communications 20020111 |
| Amyloid-beta deposits in the cerebral cortex of the aged common marmoset (Callithrix jacchus): incidence and chemical composition. | Acta neuropathologica 20020101 |
| A partially structured species of beta 2-microglobulin is significantly populated under physiological conditions and involved in fibrillogenesis. | The Journal of biological chemistry 20011214 |
| Solution conditions can promote formation of either amyloid protofilaments or mature fibrils from the HypF N-terminal domain. | Protein science : a publication of the Protein Society 20011201 |
| Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau. | Neurobiology of disease 20011201 |
| Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta(1-42). | Journal of neuroscience research 20011115 |
| Plasmin cleaves Abeta42 in vitro and prevents its aggregation into beta-pleated sheet structures. | Neuroreport 20010917 |
| The molecular chaperone, alpha-crystallin, inhibits amyloid formation by apolipoprotein C-II. | The Journal of biological chemistry 20010907 |
| Role of the single disulphide bond of beta(2)-microglobulin in amyloidosis in vitro. | Protein science : a publication of the Protein Society 20010901 |
| Relationship of calbindin D28K-immunoreactive cells and neuropathological changes in the hippocampal formation of Alzheimer's disease. | Neuropathology : official journal of the Japanese Society of Neuropathology 20010901 |
| Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain. | Life sciences 20010817 |
| Plaque-induced abnormalities in neurite geometry in transgenic models of Alzheimer disease: implications for neural system disruption. | Journal of neuropathology and experimental neurology 20010801 |
| Neuroinflammation-induced acceleration of amyloid deposition in the APPV717F transgenic mouse. | The European journal of neuroscience 20010801 |
| Statistical aspects of quantitative image analysis of beta-amyloid in the APP(V717F) transgenic mouse model of Alzheimer's disease. | Journal of neuroscience methods 20010730 |
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| Multiple ligand interaction of alpha-synuclein produced various forms of protein aggregates in the presence of Abeta25-35, copper, and eosin. | Brain research 20010720 |
| Conformational characterization of oligomeric intermediates and aggregates in beta-lactoglobulin heat aggregation. | Protein science : a publication of the Protein Society 20010701 |
| Thioflavin T is a fluorescent probe of the acetylcholinesterase peripheral site that reveals conformational interactions between the peripheral and acylation sites. | The Journal of biological chemistry 20010629 |
| The relationship between the aggregational state of the amyloid-beta peptides and free radical generation by the peptides. | Journal of neurochemistry 20010601 |
| Effect of environmental factors on the kinetics of insulin fibril formation: elucidation of the molecular mechanism. | Biochemistry 20010522 |
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| Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis. | Journal of molecular biology 20010504 |
| Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome. | Neurobiology of disease 20010401 |
| Promotion of formation of amyloid fibrils by aluminium adenosine triphosphate (AlATP). | Journal of inorganic biochemistry 20010401 |
| Growth arrest of individual senile plaques in a model of Alzheimer's disease observed by in vivo multiphoton microscopy. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010201 |
| Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia. | The American journal of pathology 20010201 |
| Spectroscopic evidence for amyloid-like interfacial self-assembly of hydrophobin Sc3. | Biochemical and biophysical research communications 20010112 |
| Heterogeneous assembly of complementary peptide pairs into amyloid fibrils with alpha-beta structural transition. | Chembiochem : a European journal of chemical biology 20010108 |
| Anti-amyloidogenic activity of tetracyclines: studies in vitro. | FEBS letters 20010105 |
| Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease. | Neuroscience 20010101 |
| The morphological phenotype of beta-amyloid plaques and associated neuritic changes in Alzheimer's disease. | Neuroscience 20010101 |