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Home Other Building Blocks VUF 10460

VUF 10460

CAS No.:
1028327-66-3
Catalog Number:
AG0096X6
Molecular Formula:
C15H19N5
Molecular Weight:
269.3449
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥98%
1 week
United States
$91
- +
5mg
98%
1 week
United States
$140
- +
10mg
98%
1 week
United States
$196
- +
25mg
98%
1 week
United States
$335
- +
50mg
98%
1 week
United States
$543
- +
100mg
98%
1 week
United States
$821
- +
Product Description
Catalog Number:
AG0096X6
Chemical Name:
VUF 10460
CAS Number:
1028327-66-3
Molecular Formula:
C15H19N5
Molecular Weight:
269.3449
MDL Number:
MFCD00055218
IUPAC Name:
4-(4-methylpiperazin-1-yl)-6-phenylpyrimidin-2-amine
InChI:
InChI=1S/C15H19N5/c1-19-7-9-20(10-8-19)14-11-13(17-15(16)18-14)12-5-3-2-4-6-12/h2-6,11H,7-10H2,1H3,(H2,16,17,18)
InChI Key:
NIJGWJIOMPHDBP-UHFFFAOYSA-N
SMILES:
CN1CCN(CC1)c1nc(N)nc(c1)c1ccccc1
Properties
Complexity:
297  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
269.164g/mol
Formal Charge:
0
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
269.352g/mol
Monoisotopic Mass:
269.164g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
58.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.8  
Literature
Title Journal
Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H₄ and the ion channel serotonin 5-HT₃A. Bioorganic & medicinal chemistry letters 20110915
Structure-activity studies on a series of a 2-aminopyrimidine-containing histamine H4 receptor ligands. Journal of medicinal chemistry 20081023
Rotationally constrained 2,4-diamino-5,6-disubstituted pyrimidines: a new class of histamine H4 receptor antagonists with improved druglikeness and in vivo efficacy in pain and inflammation models. Journal of medicinal chemistry 20081023
Properties