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MOEXIPRILAT HYDRATE

CAS No.:
103775-14-0
Catalog Number:
AG008WUM
Molecular Formula:
Molecular Weight:
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Product Description
Catalog Number:
AG008WUM
Chemical Name:
MOEXIPRILAT HYDRATE
CAS Number:
103775-14-0
MDL Number:
MFCD08063675
IUPAC Name:
(3S)-2-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
InChI:
InChI=1S/C25H30N2O7/c1-15(26-19(24(29)30)10-9-16-7-5-4-6-8-16)23(28)27-14-18-13-22(34-3)21(33-2)12-17(18)11-20(27)25(31)32/h4-8,12-13,15,19-20,26H,9-11,14H2,1-3H3,(H,29,30)(H,31,32)/t15-,19-,20-/m0/s1
InChI Key:
CMPAGYDKASJORH-YSSFQJQWSA-N
UNII:
H3753190JS
Properties
Complexity:
711  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
0
Exact Mass:
470.205g/mol
Formal Charge:
0
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
470.522g/mol
Monoisotopic Mass:
470.205g/mol
Rotatable Bond Count:
10  
Topological Polar Surface Area:
125A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.5  
Literature
Title Journal
Metabolism of moexipril to moexiprilat: determination of in vitro metabolism using HPLC-ES-MS. Medicinal chemistry (Shariqah (United Arab Emirates)) 20070101
Monitoring the metabolism of moexipril to moexiprilat using high-performance liquid chromatography-electrospray ionization mass spectrometry. Journal of chromatographic science 20060401
The influence of oestrogen-deficiency and ACE inhibition on the progression of myocardial hypertrophy in spontaneously hypertensive rats. European journal of heart failure 20051201
Moexipril shows a long duration of action related to an extended pharmacokinetic half-life and prolonged ACE inhibition. International journal of clinical pharmacology and therapeutics 20020101
Pharmacological and toxicological studies of the new angiotensin converting enzyme inhibitor moexipril hydrochloride. Arzneimittel-Forschung 19970201
Properties