Name: Name:Tofogliflozin hydrate
Brand: Angene
SKU: AG008TN9
Rating: 90 (10 reviews)

Tofogliflozin hydrate

CAS No.:

1201913-82-7

Catalog Number:

AG008TN9

Molecular Formula:

C22H28O7

Molecular Weight:

404.4535

Pack Size

Purity

Availability

Location

Price(USD)

Quantity

1mg

≥95%

1 week

United States

$91

- +

5mg

98%

1 week

United States

$196

- +

10mg

98%

1 week

United States

$279

- +

25mg

≥95%

1 week

United States

$535

- +

50mg

98%

1 week

United States

$807

- +

Product Description

Catalog Number:

AG008TN9

Chemical Name:

Tofogliflozin hydrate

CAS Number:

1201913-82-7

Molecular Formula:

C22H28O7

Molecular Weight:

404.4535

MDL Number:

MFCD27665464

IUPAC Name:

(3S,3'R,4'S,5'S,6'R)-5-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol;hydrate

InChI:

InChI=1S/C22H26O6.H2O/c1-2-13-3-5-14(6-4-13)9-15-7-8-16-12-27-22(17(16)10-15)21(26)20(25)19(24)18(11-23)28-22;/h3-8,10,18-21,23-26H,2,9,11-12H2,1H3;1H2/t18-,19-,20+,21-,22+;/m1./s1

InChI Key:

ZXOCGDDVNPDRIW-NHFZGCSJSA-N

SMILES:

OC[C@H]1O[C@]2(OCc3c2cc(cc3)Cc2ccc(cc2)CC)[C@@H]([C@H]([C@@H]1O)O)O.O

UNII:

P8DD8KX4O4

Properties

Complexity:

521

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Exact Mass:

404.184g/mol

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Molecular Weight:

404.459g/mol

Monoisotopic Mass:

404.184g/mol

Rotatable Bond Count:

Topological Polar Surface Area:

100A^2

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

Literature

Title	Journal
Tofogliflozin: first global approval.	Drugs 20140601
Discovery of tofogliflozin, a novel C-arylglucoside with an O-spiroketal ring system, as a highly selective sodium glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes.	Journal of medicinal chemistry 20120913
Tofogliflozin, a potent and highly specific sodium/glucose cotransporter 2 inhibitor, improves glycemic control in diabetic rats and mice.	The Journal of pharmacology and experimental therapeutics 20120601
[Research progress of sodium-glucose co-transporter 2 inhibitors for treatment of type 2 diabetes].	Yao xue xue bao = Acta pharmaceutica Sinica 20120601

Properties