N-[2-({[(2E)-3-(4-chlorophenyl)prop-2-en-1-yl](methyl)amino}methyl)phenyl]-4-methoxybenzenesulfonamide; phosphoric acid
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CaMKII inhibition hyperpolarizes membrane and blocks nitrergic IJP by closing a Cl(-) conductance in intestinal smooth muscle. | American journal of physiology. Gastrointestinal and liver physiology 20120715 |
Examining the effect of the CaMKII inhibitor administration in the locus coeruleus on the naloxone-precipitated morphine withdrawal signs in rats. | Behavioural brain research 20120115 |
Calmodulin kinase II inhibition prevents arrhythmias in RyR2(R4496C+/-) mice with catecholaminergic polymorphic ventricular tachycardia. | Journal of molecular and cellular cardiology 20110101 |
Modulations of NeuroD activity contribute to the differential effects of morphine and fentanyl on dendritic spine stability. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100616 |
L-type Ca(2+) channel facilitation mediated by H(2)O(2)-induced activation of CaMKII in rat ventricular myocytes. | Journal of molecular and cellular cardiology 20100401 |
CaMKII-independent effects of KN93 and its inactive analog KN92: reversible inhibition of L-type calcium channels. | Biochemical and biophysical research communications 20060714 |
KN-93 (2-[N-(2-hydroxyethyl)]-N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine), a calcium/calmodulin-dependent protein kinase II inhibitor, is a direct extracellular blocker of voltage-gated potassium channels. | The Journal of pharmacology and experimental therapeutics 20060401 |
Calcium signaling stimulates translation of HIF-alpha during hypoxia. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301 |
CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels. | Nature neuroscience 20060101 |
Ca(2+)/calmodulin-protein kinase IIalpha in the trigeminal subnucleus caudalis contributes to neuropathic pain following inferior alveolar nerve transection. | Experimental neurology 20050401 |
Visualization of synaptic Ca2+ /calmodulin-dependent protein kinase II activity in living neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050323 |
A CaMKII/calcineurin switch controls the direction of Ca(2+)-dependent growth cone guidance. | Neuron 20040916 |
Regulation of cyclin D1/Cdk4 complexes by calcium/calmodulin-dependent protein kinase I. | The Journal of biological chemistry 20040409 |
Roles of CaMKII, PKA, and PKC in the induction and maintenance of LTP of C-fiber-evoked field potentials in rat spinal dorsal horn. | Journal of neurophysiology 20040301 |
Ca2+ and AMPK both mediate stimulation of glucose transport by muscle contractions. | Diabetes 20040201 |
Reversal of morphine antinociceptive tolerance by acute spinal inhibition of Ca(2+)/calmodulin-dependent protein kinase II. | European journal of pharmacology 20030328 |
Calcium/calmodulin-dependent kinase II is involved in the facilitating effect of clozapine on NMDA- and electrically evoked responses in the medial prefrontal cortical pyramidal cells. | Synapse (New York, N.Y.) 20030315 |
Cellular mechanisms of the acute increase of glutamate release induced by nerve growth factor in rat cerebral cortex. | Neuropharmacology 20030301 |
Calcium-calmodulin-dependent protein kinase II contributes to spinal cord central sensitization. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020515 |
KN-93 inhibition of G protein signaling is independent of the ability of Ca2+/calmodulin-dependent protein kinase II to phosphorylate phospholipase Cbeta3 on 537-Ser. | Molecular and cellular endocrinology 20010425 |