2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3
| Title | Journal |
|---|---|
| Human hepatic metabolism of the anti-osteoporosis drug eldecalcitol involves sterol C4-methyl oxidase. | Pharmacology research & perspectives 20150301 |
| Eldecalcitol, a vitamin D analog, reduces bone turnover and increases trabecular and cortical bone mass, density, and strength in ovariectomized cynomolgus monkeys. | Bone 20131101 |
| Eldecalcitol normalizes bone turnover markers regardless of their pre-treatment levels. | Current medical research and opinion 20120901 |
| Bone effects of vitamin D - Discrepancies between in vivo and in vitro studies. | Archives of biochemistry and biophysics 20120701 |
| [New approved drugs for osteoporosis in Japan]. | Clinical calcium 20120601 |
| Combination therapy with eldecalcitol and alendronate has therapeutic advantages over monotherapy by improving bone strength. | Bone 20120501 |
| Eldecalcitol for the treatment of osteoporosis. | Drugs of today (Barcelona, Spain : 1998) 20120301 |
| Daily administration of eldecalcitol (ED-71), an active vitamin D analog, increases bone mineral density by suppressing RANKL expression in mouse trabecular bone. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20120201 |
| Process development for the practical production of eldecalcitol by linear, convergent and biomimetic syntheses. | Anticancer research 20120101 |
| The vitamin D analog 1α,25-Dihydroxy-2β-(3-Hydroxypropyloxy) vitamin D(3) (Eldecalcitol) is a potent regulator of calcium and phosphate metabolism. | Calcified tissue international 20111101 |
| [Frontiers in vitamin D; basic research and clinical application. Exploratory research, biological characteristic and pharmacokinetics of eldecalcitol, a new active vitamin D derivative]. | Clinical calcium 20111101 |
| [Frontiers in vitamin D; basic research and clinical application. Eldecalcitol: the effect on bones and calcium metabolism]. | Clinical calcium 20111101 |
| [Frontiers in vitamin D; Basic research and clinical application. The effects of eldecalcitol on bone mineral density and fracture prevention--Post hoc analysis]. | Clinical calcium 20111101 |
| [Frontiers in vitamin D; Basic research and clinical application. Effect of eldecalcitol on bone structure]. | Clinical calcium 20111101 |
| A new active vitamin D3 analog, eldecalcitol, prevents the risk of osteoporotic fractures--a randomized, active comparator, double-blind study. | Bone 20111001 |
| Eldecalcitol: a review of its use in the treatment of osteoporosis. | Drugs 20110910 |
| Effect of eldecalcitol, an active vitamin D analog, on hip structure and biomechanical properties: 3D assessment by clinical CT. | Bone 20110901 |
| [Diagnostic imaging of treatment in osteoporosis; new active vitamin D]. | Clinical calcium 20110701 |
| Suppression of PTH by the vitamin D analog eldecalcitol is modulated by its high affinity for the serum vitamin D-binding protein and resistance to metabolism. | Journal of cellular biochemistry 20110501 |
| [Eldecalcitol (ED-71)]. | Clinical calcium 20110101 |
| [ASBMR 2010 report. Meeting report on the ASBMR. Obstacles in medicine for osteoporosis]. | Clinical calcium 20110101 |
| Hydrogen/deuterium exchange reveals distinct agonist/partial agonist receptor dynamics within vitamin D receptor/retinoid X receptor heterodimer. | Structure (London, England : 1993) 20101013 |
| Comparison of the effects of eldecalcitol and alfacalcidol on bone and calcium metabolism. | The Journal of steroid biochemistry and molecular biology 20100701 |
| Synthesis and preliminary biological evaluation of 20-epi-eldecalcitol [20-epi-1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3: 20-epi-ED-71]. | The Journal of steroid biochemistry and molecular biology 20100701 |
| Eldecalcitol is less effective in suppressing parathyroid hormone compared to calcitriol in vivo. | The Journal of steroid biochemistry and molecular biology 20100701 |
| D-hormone derivatives for the treatment of osteoporosis: from alfacalcidol to eldecalcitol. | Mini reviews in medicinal chemistry 20091001 |
| Synthesis of all possible A-ring diastereomers at the 1- and 3-positions of 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3 (ED-71) using C2-symmetrical epoxide as a common starting material. | Anticancer research 20090901 |
| [New bone density conservation agents for osteoporosis under research and development: ED-71]. | Nihon rinsho. Japanese journal of clinical medicine 20071128 |
| Synthesis and biological evaluation of a 3-positon epimer of 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3 (ED-71). | The Journal of steroid biochemistry and molecular biology 20070301 |
| ED-71, a new active vitamin D3, increases bone mineral density regardless of serum 25(OH)D levels in osteoporotic subjects. | The Journal of steroid biochemistry and molecular biology 20070301 |
| ED-71, a novel vitamin D analog, promotes bone formation and angiogenesis and inhibits bone resorption after bone marrow ablation. | Bone 20070201 |
| 1Alpha,25-dihydroxy-2beta(3-hydroxypropoxy)vitamin D3 (ED-71) suppressed callus remodeling but did not interfere with fracture healing in rat femora. | Bone 20070101 |
| [Therapeutic agents for disorders of bone and calcium metabolism: ED-71]. | Clinical calcium 20070101 |
| Synthesis of putative metabolites of 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D(3) (ED-71). | Steroids 20060701 |
| [Progress in research on vitamin D analogs]. | Clinical calcium 20060701 |
| [Vitamin-D analogues for osteoporosis]. | Clinical calcium 20060701 |
| [New horizons of ED-71 (vitamin D analog)]. | Clinical calcium 20060101 |
| The determination of 2beta-(3-hydroxypropoxy)-1alpha,25-dihydroxy vitamin D3 (ED-71) in human serum by high-performance liquid chromatography-electrospray tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050905 |
| A new active vitamin D, ED-71, increases bone mass in osteoporotic patients under vitamin D supplementation: a randomized, double-blind, placebo-controlled clinical trial. | The Journal of clinical endocrinology and metabolism 20050901 |
| [Vitamin D and its derivatives as anti-osteoporotic drugs]. | Clinical calcium 20050401 |
| [Influencing factors on distraction osteogenesis]. | Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20040701 |
| [The trend in the development of the active vitamin D3 and its analogues]. | Nihon rinsho. Japanese journal of clinical medicine 20040501 |
| ED-71 Chugai. | Current opinion in investigational drugs (London, England : 2000) 20040401 |
| [ED-71]. | Nihon rinsho. Japanese journal of clinical medicine 20040201 |
| A new active vitamin D analog, ED-71, causes increase in bone mass with preferential effects on bone in osteoporotic patients. | Journal of cellular biochemistry 20030201 |
| Rationale for active vitamin D and analogs in the treatment of osteoporosis. | Journal of cellular biochemistry 20030201 |
| [Osteoporosis]. | Ryumachi. [Rheumatism] 20021201 |
| ED-71, a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis. | Bone 20020401 |
| [Drugs in development for the treatment of osteoporosis: Active vitamin D analog(ED-71)]. | Nihon rinsho. Japanese journal of clinical medicine 20020301 |
| History of the development of new vitamin D analogs: studies on 22-oxacalcitriol (OCT) and 2beta-(3-hydroxypropoxy)calcitriol (ED-71). | Steroids 20010101 |
| Synthesis and biological characterization of 1alpha,24,25-trihydroxy-2beta-(3-hydroxypropoxy)vitamin D(3) (24-hydroxylated ED-71). | Steroids 20010101 |
| Synthetic studies of vitamin D analogues. XIV. Synthesis and calcium regulating activity of vitamin D3 analogues bearing a hydroxyalkoxy group at the 2 beta-position. | Chemical & pharmaceutical bulletin 19930601 |
| Effects of two new vitamin D3 derivatives, 22-oxa-1 alpha-25-dihydroxyvitamin D3 (OCT) and 2 beta-(3-hydroxypropoxy)-1 alpha, 25-dihydroxyvitamin D3 (ED-71), on bone metabolism in organ culture. | Bone 19930101 |