Q-VD-Oph
| Title | Journal |
|---|---|
| The anti-caspase inhibitor Q-VD-OPH prevents AIDS disease progression in SIV-infected rhesus macaques. | The Journal of clinical investigation 20180402 |
| 3-Monochloro-1,2-propanediol (3-MCPD) induces apoptosis via mitochondrial oxidative phosphorylation system impairment and the caspase cascade pathway. | Toxicology 20161130 |
| An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death. | The Journal of biological chemistry 20150821 |
| Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism. | Breast cancer research and treatment 20130101 |
| Differential effects of the autophagy inhibitors 3-methyladenine and chloroquine on spontaneous and TNF-α-induced neutrophil apoptosis. | Apoptosis : an international journal on programmed cell death 20121001 |
| The pan-caspase inhibitor Q-VD-OPh has anti-leukemia effects and can interact with vitamin D analogs to increase HPK1 signaling in AML cells. | Leukemia research 20120701 |
| Calpain activation is involved in acute manganese neurotoxicity in the rat striatum in vivo. | Experimental neurology 20120101 |
| Radiolabeled isatin binding to caspase-3 activation induced by anti-Fas antibody. | Nuclear medicine and biology 20120101 |
| Dose-dependent effects of the caspase inhibitor Q-VD-OPh on different apoptosis-related processes. | Journal of cellular biochemistry 20111101 |
| Astragalin heptaacetate-induced cell death in human leukemia cells is dependent on caspases and activates the MAPK pathway. | Cancer letters 20111001 |
| Multiple caspases mediate acute renal cell apoptosis induced by bacterial cell wall components. | Renal failure 20110101 |
| Caspase activation is not required for villous cytotrophoblast fusion into syncytiotrophoblasts. | Placenta 20101101 |
| Mitochondrial remodeling following fission inhibition by 15d-PGJ2 involves molecular changes in mitochondrial fusion protein OPA1. | Biochemical and biophysical research communications 20100903 |
| Autophagy is the predominant process induced by arsenite in human lymphoblastoid cell lines. | Toxicology and applied pharmacology 20100501 |
| Macrophage response to apoptotic cells varies with the apoptotic trigger and is not altered by a deficiency in LRP expression. | Journal of innate immunity 20100401 |
| The small 11 kDa nonstructural protein of human parvovirus B19 plays a key role in inducing apoptosis during B19 virus infection of primary erythroid progenitor cells. | Blood 20100204 |
| Contractile response of norepinephrine is modulated by caspase-3 in adult rat ventricular myocytes isolated from septic rat heart. | Pharmacological research 20091001 |
| Sex differences in caspase activation after stroke. | Stroke 20090501 |
| Modulation of caspase-independent cell death leads to resensitization of imatinib mesylate-resistant cells. | Cancer research 20090401 |
| Small-molecule activation of neuronal cell fate. | Nature chemical biology 20080701 |
| Enteropathogenic E. coli-induced barrier function alteration is not a consequence of host cell apoptosis. | American journal of physiology. Gastrointestinal and liver physiology 20080501 |
| Straw blood cell count, growth, inhibition and comparison to apoptotic bodies. | BMC cell biology 20080101 |
| Influence of pan-caspase inhibitors on coxsackievirus B3-infected CD19+ B lymphocytes. | Apoptosis : an international journal on programmed cell death 20070901 |
| Caspase inhibition reduces cardiac myocyte dyshomeostasis and improves cardiac contractile function after major burn injury. | Journal of applied physiology (Bethesda, Md. : 1985) 20070701 |
| Novel molecular imaging of cell death in experimental cerebral stroke. | Brain research 20070504 |
| Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia. | Cell death and differentiation 20070401 |
| Broad-spectrum caspase inhibitors: from myth to reality? | Cell death and differentiation 20070201 |
| Caspase inhibition blocks cell death and results in cell cycle arrest in cytokine-deprived hematopoietic cells. | The Journal of biological chemistry 20070126 |
| Retinal ganglion cell survival in development: mechanisms of retinal growth hormone action. | Experimental eye research 20061101 |
| 7-Bromoindirubin-3'-oxime induces caspase-independent cell death. | Oncogene 20061012 |
| Caspases and calpain are independent mediators of cisplatin-induced endothelial cell necrosis. | American journal of physiology. Renal physiology 20060901 |
| Copper-induced stimulation of extracellular signal-regulated kinase in trout hepatocytes: the role of reactive oxygen species, Ca2+, and cell energetics and the impact of extracellular signal-regulated kinase signaling on apoptosis and necrosis. | Toxicological sciences : an official journal of the Society of Toxicology 20060801 |
| Motexafin gadolinium induces mitochondrially-mediated caspase-dependent apoptosis. | Apoptosis : an international journal on programmed cell death 20051001 |
| Functional role of caspases in heat-induced testicular germ cell apoptosis. | Biology of reproduction 20050301 |
| A novel systemically active caspase inhibitor attenuates the toxicities of MPTP, malonate, and 3NP in vivo. | Neurobiology of disease 20041101 |
| Q-VD-OPh, next generation caspase inhibitor. | Advances in experimental medicine and biology 20040101 |
| Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties. | Apoptosis : an international journal on programmed cell death 20030801 |
| Neutrophil-independent mechanisms of caspase-1- and IL-18-mediated ischemic acute tubular necrosis in mice. | The Journal of clinical investigation 20021015 |