beta-Escin
| Title | Journal |
|---|---|
| Escin augments the efficacy of gemcitabine through down-regulation of nuclear factor-κB and nuclear factor-κB-regulated gene products in pancreatic cancer both in vitro and in vivo. | Journal of cancer research and clinical oncology 20120501 |
| [Application of recording SK2 current in human atrial myocytes by perforated patch clamp techniques with the mix of beta-escin and amphotericin B]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20120501 |
| [Effects of sodium aescinate on the apoptosis-related genes in lung injury induced by intestinal ischemia reperfusion in rats]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20120301 |
| Triterpene saponins of Quillaja saponaria show strong aphicidal and deterrent activity against the pea aphid Acyrthosiphon pisum. | Pest management science 20120201 |
| 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²⁺ desensitization in permeabilized rat mesenteric artery. | Naunyn-Schmiedeberg's archives of pharmacology 20120201 |
| Intracellular drug delivery in Leishmania-infected macrophages: Evaluation of saponin-loaded PLGA nanoparticles. | Journal of drug targeting 20120201 |
| Mixture designs in the optimisation of PLGA nanoparticles: influence of organic phase composition on β-aescin encapsulation. | Journal of microencapsulation 20120101 |
| β-Escin sodium inhibits inducible nitric oxide synthase expression via downregulation of the JAK/STAT pathway in A549 cells. | Molecular carcinogenesis 20111201 |
| The impact of sodium aescinate on acute lung injury induced by oleic acid in rats. | Experimental lung research 20111201 |
| PLGA nanoparticles loaded with the antileishmanial saponin β-aescin: factor influence study and in vitro efficacy evaluation. | International journal of pharmaceutics 20111125 |
| Protective effect of aescin from the seeds of Aesculus hippocastanum on liver injury induced by endotoxin in mice. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20111115 |
| Synergistic interactions of saponins and monoterpenes in HeLa cells, Cos7 cells and in erythrocytes. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20111015 |
| Protective effect of sodium aescinate on lung injury induced by methyl parathion. | Human & experimental toxicology 20111001 |
| Apoptosis of human cholangiocarcinoma cell lines induced by β-escin through mitochondrial caspase-dependent pathway. | Phytotherapy research : PTR 20111001 |
| A new cyclodextrin-grafted viscose loaded with aescin formulations for a cosmeto-textile approach to chronic venous insufficiency. | Journal of materials science. Materials in medicine 20111001 |
| 19,20-EpDPE, a bioactive CYP450 metabolite of DHA monoacyglyceride, decreases Ca²⁺ sensitivity in human pulmonary arteries. | American journal of physiology. Heart and circulatory physiology 20111001 |
| The potent anti-inflammatory agent escin does not increase corticosterone secretion and immune cell apoptosis in mice. | Fitoterapia 20110901 |
| Rho-kinase inhibition attenuates calcium-induced contraction in β-escin but not Triton X-100 permeabilized rabbit femoral artery. | Journal of muscle research and cell motility 20110901 |
| Aescin: microcirculatory activity. Effects of accessory components on clinical and microcirculatory efficacy. | Panminerva medica 20110901 |
| Ca(2+)-dependent contraction by the saponoside escin in rat vena cava: implications in venotonic treatment of varicose veins. | Journal of vascular surgery 20110801 |
| Escin attenuates cerebral edema induced by acute omethoate poisoning. | Toxicology mechanisms and methods 20110601 |
| Hydrogen sulphide inhibits carbachol-induced contractile responses in β-escin permeabilized guinea-pig taenia caecum. | European journal of pharmacology 20110511 |
| Escin exerts synergistic anti-inflammatory effects with low doses of glucocorticoids in vivo and in vitro. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20110215 |
| Escin attenuates acute lung injury induced by endotoxin in mice. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110118 |
| Escin attenuates cognitive deficits and hippocampal injury after transient global cerebral ischemia in mice via regulating certain inflammatory genes. | Neurochemistry international 20100901 |
| Synergistic effects of beta-aescin and 5-fluorouracil in human hepatocellular carcinoma SMMC-7721 cells. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20100701 |
| Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells. | The Journal of pharmacology and experimental therapeutics 20100701 |
| Beneficial effects of Aesculus hippocastanum L. seed extract on the body's own antioxidant defense system on subacute administration. | Journal of ethnopharmacology 20100504 |
| Determination of escin content in androgenic embryos and hairy root culture of Aesculus hippocastanum. | Pharmaceutical biology 20100501 |
| Simultaneous analysis of isomers of escin saponins in human plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study after oral administration. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100401 |
| Effects of escin mixture from the seeds of Aesculus hippocastanum on obesity in mice fed a high fat diet. | Pharmaceutical biology 20100301 |
| Dual effects of sodium aescinate on vascular tension in rat thoracic aorta. | Microvascular research 20100101 |
| Beta-escin has potent anti-allergic efficacy and reduces allergic airway inflammation. | BMC immunology 20100101 |
| Signalling pathways involved in the contractile response to 5-HT in the human pulmonary artery. | The European respiratory journal 20091201 |
| [Effects of intrathecal escin and clonidine in the treatment of neuropathic pain in rats]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090901 |
| Phosphorylation-dependent autoinhibition of myosin light chain phosphatase accounts for Ca2+ sensitization force of smooth muscle contraction. | The Journal of biological chemistry 20090807 |
| Pilot postoperative ileus study of escin in cancer patients after colorectal surgery. | World journal of surgery 20090201 |
| The effects of reactive oxygen species on calcium- and carbachol-induced contractile responses in beta-escin permeabilized rat bladder. | Naunyn-Schmiedeberg's archives of pharmacology 20081201 |
| Beta-escin, a natural triterpenoid saponin from Chinese horse chestnut seeds, depresses HL-60 human leukaemia cell proliferation and induces apoptosis. | The Journal of pharmacy and pharmacology 20080901 |
| Effects of omega-hydroxylase product on distal human pulmonary arteries. | American journal of physiology. Heart and circulatory physiology 20080301 |
| Aescin and troxerutin as a successful combination for the treatment of inner ear perfusion disturbances. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20080301 |
| Anti-obesity effects of escins extracted from the seeds of Aesculus turbinata BLUME (Hippocastanaceae). | Chemical & pharmaceutical bulletin 20080101 |
| Effect of beta-escin sodium on endothelial cells proliferation, migration and apoptosis. | Vascular pharmacology 20080101 |
| Intracellular calcium stores in beta-escin skinned rat and guinea-pig bladders. | European journal of pharmacology 20070702 |
| Endothelium protectant and contractile effects of the antivaricose principle escin in rat aorta. | Vascular pharmacology 20070701 |
| Intestinal inflammation downregulates smooth muscle CPI-17 through induction of TNF-alpha and causes motility disorders. | American journal of physiology. Gastrointestinal and liver physiology 20070501 |
| Use of solid phase extraction (SPE) to evaluate in vitro skin permeation of aescin. | Die Pharmazie 20070501 |
| Aescin protection of human vascular endothelial cells exposed to cobalt chloride mimicked hypoxia and inflammatory stimuli. | Planta medica 20070301 |
| Mechanism underlying H2O2-induced inhibition of acetylcholine-induced contraction in rabbit tracheal smooth muscle. | European journal of pharmacology 20070227 |
| Pkd2+/- vascular smooth muscles develop exaggerated vasocontraction in response to phenylephrine stimulation. | Journal of the American Society of Nephrology : JASN 20070201 |
| Identification of novel saponins from edible seeds of Japanese horse chestnut (Aesculus turbinata Blume) after treatment with wooden ashes and their nutraceutical activity. | Journal of pharmaceutical and biomedical analysis 20060828 |
| Involvement of Rho kinase and protein kinase C in carbachol-induced calcium sensitization in beta-escin skinned rat and guinea-pig bladders. | British journal of pharmacology 20060601 |
| Beta-escin inhibits colonic aberrant crypt foci formation in rats and regulates the cell cycle growth by inducing p21(waf1/cip1) in colon cancer cells. | Molecular cancer therapeutics 20060601 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Densitometric thin-layer chromatographic determination of aescin in a herbal medicinal product containing Aesculus and Vitis dry extracts. | Journal of chromatography. A 20060421 |
| Occupational asthma related to aescin inhalation. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060301 |
| Medical expulsive treatment of distal-ureteral stones using tamsulosin: a single-center experience. | Journal of endourology 20060101 |
| Escin: inhibiting inflammation and promoting gastrointestinal transit to attenuate formation of postoperative adhesions. | World journal of surgery 20051201 |
| The use of tamsulosin in the medical treatment of ureteral calculi: where do we stand? | Urological research 20051201 |
| Effects of beta-Aescin on the expression of nuclear factor-kappaB and tumor necrosis factor-alpha after traumatic brain injury in rats. | Journal of Zhejiang University. Science. B 20050101 |
| Characteristic fragmentation behavior of some glucuronide-type triterpenoid saponins using electrospray ionization tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20050101 |
| Evaluation of biosurfactants for crude oil contaminated soil washing. | Chemosphere 20041201 |
| Development of cultured rabbit corneal epithelium for drug permeation studies: a comparison with excised rabbit cornea. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20041201 |
| Effects of escin on indinavir crystallization time in the urine of patients with HIV-I infection: a multicenter, randomized, open-label, controlled, four-period crossover trial. | Clinical therapeutics 20041201 |
| [Clinical effect of escin on patients with cutaneous pruritus caused by blood stasis and wind-dryness]. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20041101 |
| Beta-escin diminishes voltage-gated calcium current rundown in perforated patch-clamp recordings from rat primary afferent neurons. | Journal of neuroscience methods 20041015 |
| Actions downstream of cyclic GMP/protein kinase G can reverse protein kinase C-mediated phosphorylation of CPI-17 and Ca²⁺ sensitization in smooth muscle. | The Journal of biological chemistry 20040709 |
| Differential effects of FK506 and cyclosporin A on catecholamine release from bovine adrenal chromaffin cells. | Autonomic & autacoid pharmacology 20040701 |
| Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon. | British journal of pharmacology 20040601 |
| Protective effects of sodium beta-aescin on ischemia-reperfusion injury in rat brain. | Yao xue xue bao = Acta pharmaceutica Sinica 20040601 |
| Over-expression of FK506-binding protein FKBP12.6 alters excitation-contraction coupling in adult rabbit cardiomyocytes. | The Journal of physiology 20040501 |
| Microcirculatory efficacy of topical treatment with aescin + essential phospholipids gel in venous insufficiency and hypertension: new clinical observations. | Angiology 20040101 |
| Microcirculatory efficacy of topical treatment with aescin + essential phospholipids gel on transcutaneous PO2 in venous insufficiency. | Angiology 20040101 |
| Variations in plasma free radicals with topical aescin + essential phospholipids gel in venous hypertension: new clinical data. | Angiology 20040101 |
| Efficacy of topical treatment with aescin + essential phospholipids gel in a microcirculatory model of venous insufficiency. | Angiology 20040101 |
| Efficacy of topical treatment with aescin + essential phospholipids gel in venous insufficiency and hypertension. | Angiology 20040101 |
| Efficacy of topical treatment with aescin + essential phospholipids gel on capillary fragility. | Angiology 20040101 |
| Perforated patch recording of L-type calcium current with beta-escin in guinea pig ventricular myocytes. | Acta pharmacologica Sinica 20031101 |
| Dependence of Ca2+-induced contraction on ATP in alpha-toxin-permeabilized preparations of rat femoral artery. | Journal of pharmacological sciences 20031001 |
| [Inhibitory effects of salviae miltiorrhizae and beta-aescinom natrium on the postburn acute lung injury in rats]. | Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20031001 |
| Characterization of alpha-soluble N-ethylmaleimide-sensitive fusion attachment protein in alveolar type II cells: implications in lung surfactant secretion. | American journal of respiratory cell and molecular biology 20030901 |
| Effects of adenovirus-mediated sorcin overexpression on excitation-contraction coupling in isolated rabbit cardiomyocytes. | Circulation research 20030725 |
| Measurement of the dissociation constant of Fluo-3 for Ca2+ in isolated rabbit cardiomyocytes using Ca2+ wave characteristics. | Cell calcium 20030701 |
| CaM kinase IIalpha mediates norepinephrine-induced translocation of cytosolic phospholipase A2 to the nuclear envelope. | Journal of cell science 20030115 |
| [Plant preparations of Sofarma in gynecological practice]. | Akusherstvo i ginekologiia 20030101 |
| Sphingosylphosphorylcholine is a novel messenger for Rho-kinase-mediated Ca2+ sensitization in the bovine cerebral artery: unimportant role for protein kinase C. | Circulation research 20020726 |
| Escin/diethylammonium salicylate/heparin combination gels for the topical treatment of acute impact injuries: a randomised, double blind, placebo controlled, multicentre study. | British journal of sports medicine 20020601 |
| Xestospongin C, a novel blocker of IP3 receptor, attenuates the increase in cytosolic calcium level and degranulation that is induced by antigen in RBL-2H3 mast cells. | British journal of pharmacology 20020401 |
| Extensive skinning of cell membrane diminishes the force-inhibiting effect of okadaic acid on smooth muscles of Guinea pig hepatic portal vein. | The Japanese journal of physiology 20020401 |
| Comparative study of Venostasin and Pycnogenol in chronic venous insufficiency. | Phytotherapy research : PTR 20020301 |
| [Pathogenetic basis for using prodectin and teonicol, redergin and aescuzan in complex treatment of chronic gastritis]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20020101 |
| Aescin: pharmacology, pharmacokinetics and therapeutic profile. | Pharmacological research 20010901 |
| Mechanisms of direct inhibitory action of ketamine on vascular smooth muscle in mesenteric resistance arteries. | Anesthesiology 20010801 |
| Efficacy and tolerability of escin/diethylamine salicylate combination gels in patients with blunt injuries of the extremities. | International journal of sports medicine 20010801 |
| Regulation by GDI of RhoA/Rho-kinase-induced Ca2+ sensitization of smooth muscle myosin II. | American journal of physiology. Cell physiology 20010701 |
| Effects of halothane on sarcoplasmic reticulum calcium release channels in porcine airway smooth muscle cells. | Anesthesiology 20010701 |
| Synexin and GTP increase surfactant secretion in permeabilized alveolar type II cells. | American journal of physiology. Lung cellular and molecular physiology 20010501 |
| Responsiveness of human varicose saphenous veins to vasoactive agents. | British journal of clinical pharmacology 20010301 |
| Inhibition of capacitative calcium entry is not obligatory for relaxation of the mouse anococcygeus by the NO/cyclic GMP signalling pathway. | British journal of pharmacology 20010201 |
| [Systemic enzyme therapy in the treatment and prevention of post-traumatic and postoperative swelling]. | Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 20010101 |
| Rational therapy of chronic venous insufficiency--chances and limits of the therapeutic use of horse-chestnut seeds extract. | BMC cardiovascular disorders 20010101 |