N-(n-Nonyl)deoxynojirimycin
| Title | Journal |
|---|---|
| Conformationally-locked N-glycosides with selective β-glucosidase inhibitory activity: identification of a new non-iminosugar-type pharmacological chaperone for Gaucher disease. | Journal of medicinal chemistry 20120809 |
| Design, synthesis, and biological evaluation of N-alkylated deoxynojirimycin (DNJ) derivatives for the treatment of dengue virus infection. | Journal of medicinal chemistry 20120712 |
| Potent aminocyclitol glucocerebrosidase inhibitors are subnanomolar pharmacological chaperones for treating gaucher disease. | Journal of medicinal chemistry 20120510 |
| Synthesis of N-substituted ε-hexonolactams as pharmacological chaperones for the treatment of N370S mutant Gaucher disease. | Organic & biomolecular chemistry 20120421 |
| The many faces of the adamantyl group in drug design. | European journal of medicinal chemistry 20110601 |
| New glucocerebrosidase inhibitors by exploration of chemical diversity of N-substituted aminocyclitols using click chemistry and in situ screening. | Journal of medicinal chemistry 20110414 |
| Synthesis of N-alkylated noeurostegines and evaluation of their potential as treatment for Gaucher's disease. | Bioorganic & medicinal chemistry letters 20110301 |
| Glucosidase inhibition enhances presentation of de-N-glycosylated hepatitis B virus epitopes by major histocompatibility complex class I in vitro and in woodchucks. | Hepatology (Baltimore, Md.) 20101001 |
| Click chemistry approach to new N-substituted aminocyclitols as potential pharmacological chaperones for Gaucher disease. | Journal of medicinal chemistry 20100722 |
| Chaperone activity of bicyclic nojirimycin analogues for Gaucher mutations in comparison with N-(n-nonyl)deoxynojirimycin. | Chembiochem : a European journal of chemical biology 20091123 |
| Promising results of the chaperone effect caused by imino sugars and aminocyclitol derivatives on mutant glucocerebrosidases causing Gaucher disease. | Blood cells, molecules & diseases 20090101 |
| Genotype-dependent sensitivity of hepatitis C virus to inhibitors of the p7 ion channel. | Hepatology (Baltimore, Md.) 20081201 |
| A dengue fever viremia model in mice shows reduction in viral replication and suppression of the inflammatory response after treatment with antiviral drugs. | The Journal of infectious diseases 20070301 |
| Action of celgosivir (6 O-butanoyl castanospermine) against the pestivirus BVDV: implications for the treatment of hepatitis C. | Antiviral chemistry & chemotherapy 20040501 |
| Inhibition of glycogen breakdown by imino sugars in vitro and in vivo. | Biochemical pharmacology 20040215 |
| Imino sugars that are less toxic but more potent as antivirals, in vitro, compared with N-n-nonyl DNJ. | Antiviral chemistry & chemotherapy 20020901 |
| Inhibition of hepatitis B virus DNA replication by imino sugars without the inhibition of the DNA polymerase: therapeutic implications. | Hepatology (Baltimore, Md.) 20010601 |
| Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: implications for the development of broad spectrum anti-hepatitis virus agents. | Proceedings of the National Academy of Sciences of the United States of America 19991012 |