sales@angenesci.com
Login | Register
logo
Structures Search
Home Other Building Blocks Cytidine,3'-azido-2',3'-dideoxy-

Cytidine,3'-azido-2',3'-dideoxy-

CAS No.:
84472-89-9
Catalog Number:
AG008I21
Molecular Formula:
C9H12N6O3
Molecular Weight:
252.2300
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98%(HPLC)
In Stock USA
United States
$151
- +
25mg
98%(HPLC)
In Stock USA
United States
$429
- +
Product Description
Catalog Number:
AG008I21
Chemical Name:
Cytidine,3'-azido-2',3'-dideoxy-
CAS Number:
84472-89-9
Molecular Formula:
C9H12N6O3
Molecular Weight:
252.2300
MDL Number:
MFCD00880598
IUPAC Name:
4-amino-1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
InChI:
InChI=1S/C9H12N6O3/c10-7-1-2-15(9(17)12-7)8-3-5(13-14-11)6(4-16)18-8/h1-2,5-6,8,16H,3-4H2,(H2,10,12,17)/t5-,6+,8+/m0/s1
InChI Key:
YIEFKLOVIROQIL-SHYZEUOFSA-N
SMILES:
OC[C@H]1O[C@H](C[C@@H]1N=[N+]=[N-])n1ccc(nc1=O)N
Properties
Complexity:
455  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
0
Exact Mass:
252.097g/mol
Formal Charge:
0
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
252.234g/mol
Monoisotopic Mass:
252.097g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
103A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.6  
Literature
Title Journal
The base component of 3'-azido-2',3'-dideoxynucleosides influences resistance mutations selected in HIV-1 reverse transcriptase. Antimicrobial agents and chemotherapy 20110801
The 3'-azido group is not the primary determinant of 3'-azido-3'-deoxythymidine (AZT) responsible for the excision phenotype of AZT-resistant HIV-1. The Journal of biological chemistry 20050812
In vitro activity of structurally diverse nucleoside analogs against human immunodeficiency virus type 1 with the K65R mutation in reverse transcriptase. Antimicrobial agents and chemotherapy 20050301
Use of a standardized cell culture assay to assess activities of nucleoside analogs against hepatitis B virus replication. Antiviral research 19920701
Synthesis and anti-HIV evaluation of 2',3'-dideoxyribo-5-chloropyrimidine analogues: reduced toxicity of 5-chlorinated 2',3'-dideoxynucleosides. Journal of medicinal chemistry 19900601
Structure-activity relationships of pyrimidine nucleosides as antiviral agents for human immunodeficiency virus type 1 in peripheral blood mononuclear cells. Journal of medicinal chemistry 19890301
Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides. Journal of medicinal chemistry 19881001
Anti-retrovirus activity of 3'-fluoro- and 3'-azido-substituted pyrimidine 2',3'-dideoxynucleoside analogues. Biochemical pharmacology 19880715
Synthesis and antiviral activity of various 3'-azido analogues of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1, HTLV-III/LAV). Journal of medicinal chemistry 19880201
Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogues of pyrimidine deoxyribonucleosides against retroviruses. Journal of medicinal chemistry 19870201
Properties