sales@angenesci.com
Login | Register
logo
Structures Search
Home Other Building Blocks Trofinetide

Trofinetide

CAS No.:
853400-76-7
Catalog Number:
AG008FMG
Molecular Formula:
C13H21N3O6
Molecular Weight:
315.3223
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
98%
1 week
United States
$240
- +
5mg
98%
1 week
United States
$607
- +
10mg
98%
1 week
United States
$890
- +
50mg
98%
1 week
United States
$2557
- +
100mg
98%
1 week
United States
$3557
- +
Product Description
Catalog Number:
AG008FMG
Chemical Name:
Trofinetide
CAS Number:
853400-76-7
Molecular Formula:
C13H21N3O6
Molecular Weight:
315.3223
MDL Number:
MFCD28502204
IUPAC Name:
(2S)-2-[[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidine-2-carbonyl]amino]pentanedioic acid
InChI:
InChI=1S/C13H21N3O6/c1-13(5-2-6-16(13)9(17)7-14)12(22)15-8(11(20)21)3-4-10(18)19/h8H,2-7,14H2,1H3,(H,15,22)(H,18,19)(H,20,21)/t8-,13-/m0/s1
InChI Key:
BUSXWGRAOZQTEY-SDBXPKJASA-N
SMILES:
NCC(=O)N1CCC[C@@]1(C)C(=O)N[C@H](C(=O)O)CCC(=O)O
UNII:
Z2ME8F52QL
Properties
Complexity:
480  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0
Exact Mass:
315.143g/mol
Formal Charge:
0
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
315.326g/mol
Monoisotopic Mass:
315.143g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
150A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-3.9  
Literature
Title Journal
NNZ-2566, a glypromate analog, attenuates brain ischemia-induced non-convulsive seizures in rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20091201
NNZ-2566: a Gly-Pro-Glu analogue with neuroprotective efficacy in a rat model of acute focal stroke. Journal of the neurological sciences 20090315
NNZ-2566, a glypromate analog, improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury. Journal of neurotrauma 20090101
NNZ-2566 treatment inhibits neuroinflammation and pro-inflammatory cytokine expression induced by experimental penetrating ballistic-like brain injury in rats. Journal of neuroinflammation 20090101
The neuroprotective activity of GPE tripeptide analogues does not correlate with glutamate receptor binding affinity. Bioorganic & medicinal chemistry letters 20060701
Analogues of the neuroprotective tripeptide Gly-Pro-Glu (GPE): synthesis and structure-activity relationships. Bioorganic & medicinal chemistry letters 20050502
Properties