6H-Purin-6-one,2-amino-9-ethyl-1,9-dihydro-
| Title | Journal |
|---|---|
| Bipyrimidine ruthenium(II) arene complexes: structure, reactivity and cytotoxicity. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20121001 |
| An in vivo highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complex largely circumvents in vitro cisplatin resistance: two linkage isomers yield the same product upon reaction with 9-ethylguanine but exhibit different cytotoxic profiles. | Metallomics : integrated biometal science 20120701 |
| Reactivity and biological properties of a series of cytotoxic PtI2(amine)2 complexes, either cis or trans configured. | Inorganic chemistry 20120206 |
| A potent ruthenium(II) antitumor complex bearing a lipophilic levonorgestrel group. | Inorganic chemistry 20110919 |
| Photocontrolled DNA binding of a receptor-targeted organometallic ruthenium(II) complex. | Journal of the American Chemical Society 20110907 |
| Contrasting reactivity and cancer cell cytotoxicity of isoelectronic organometallic iridium(III) complexes. | Inorganic chemistry 20110620 |
| Organometallic half-sandwich iridium anticancer complexes. | Journal of medicinal chemistry 20110428 |
| Oxidation of a guanine derivative coordinated to a Pt(IV) complex initiated by intermolecular nucleophilic attacks. | Dalton transactions (Cambridge, England : 2003) 20110328 |
| Bypass of N²-ethylguanine by human DNA polymerase κ. | DNA repair 20110102 |
| Issues in developing drugs for primary brain tumors: barriers and toxicities. | Toxicologic pathology 20110101 |
| HPLC-UV, MALDI-TOF-MS and ESI-MS/MS analysis of the mechlorethamine DNA crosslink at a cytosine-cytosine mismatch pair. | PloS one 20110101 |
| Poly(ADP-ribose) polymerase inhibition: a new direction for BRCA and triple-negative breast cancer? | Breast cancer research : BCR 20110101 |
| X-ray structural characterization of the bis-guanine derivative of a cisplatin analogue having just one proton on each coordinated nitrogen and a head-to-head conformation: [Pt{(+/-)-N,N'-dimethyl-2,3-diaminobutane}(9-ethyl-guanine)2]dinitrate. | Inorganic chemistry 20100906 |
| Analysis of MGMT promoter methylation status on intraoperative fresh tissue section from frameless neuronavigation needle biopsy: a preliminary study of ten patients. | Acta neurochirurgica 20100701 |
| 'Lantern-Shaped' Platinum(III) Complexes with Axially Bound 9-Ethylguanine or 1-Methylcytosine (L) of General Formula [Pt(2){HN=C(Bu)O}(4)L(2)](NO(3))(2). | Bioinorganic chemistry and applications 20100101 |
| Synthesis, Characterization, DNA Binding, and Photocleavage Activity of Oxorhenium (V) Complexes with alpha-Diimine and Quinoxaline Ligands. | Bioinorganic chemistry and applications 20100101 |
| DNA damage induced by alkylating agents and repair pathways. | Journal of nucleic acids 20100101 |
| DNA cleavage and antitumour activity of platinum(II) and copper(II) compounds derived from 4-methyl-2-N-(2-pyridylmethyl)aminophenol: spectroscopic, electrochemical and biological investigation. | Dalton transactions (Cambridge, England : 2003) 20091228 |
| Inert ruthenium half-sandwich complexes with anticancer activity. | Dalton transactions (Cambridge, England : 2003) 20091228 |
| Amide linkage isomerism as an activity switch for organometallic osmium and ruthenium anticancer complexes. | Journal of medicinal chemistry 20091210 |
| Platinum(II) compounds with chelating ligands based on pyridine and pyrimidine: synthesis, characterizations, DFT calculations, cytotoxic assays and binding to a DNA model base. | Journal of inorganic biochemistry 20090901 |
| Cytotoxic activity and cellular processing in human ovarian carcinoma cell lines of a new platinum(II) compound containing a fluorescent substituted propylene diamine ligand. | Biochemical pharmacology 20090815 |
| Expanding the pH range of metal-nucleobase complexes for acid-base chemistry: properties of bis(guanine) complexes of (bpy)Pt(II) with either two major or major and minor tautomers bonded simultaneously. | Inorganic chemistry 20090615 |
| Ruthenium polypyridyl complexes and their modes of interaction with DNA: is there a correlation between these interactions and the antitumor activity of the compounds? | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20090301 |
| Organometallic osmium(II) arene anticancer complexes containing picolinate derivatives. | Inorganic chemistry 20090216 |
| Guanine radical reaction processes: a computational description of proton transfer in X-irradiated 9-ethylguanine single crystals. | The journal of physical chemistry. B 20081225 |
| The contrasting chemistry and cancer cell cytotoxicity of bipyridine and bipyridinediol ruthenium(II) arene complexes. | Inorganic chemistry 20081215 |
| Ruthenium(III) chloride complex with a tridentate bis(arylimino)pyridine ligand: synthesis, spectra, X-ray structure, 9-ethylguanine binding pattern, and in vitro cytotoxicity. | Inorganic chemistry 20080804 |
| Incorporating molecular tools into early-stage clinical trials. | PLoS medicine 20080101 |
| In vitro anticancer activity and biologically relevant metabolization of organometallic ruthenium complexes with carbohydrate-based ligands. | Chemistry (Weinheim an der Bergstrasse, Germany) 20080101 |
| An enolisable barbiturate with adjustable hydrogen-bonding structure for UV/Vis detection of nucleic acid bases and related compounds. | Chemistry (Weinheim an der Bergstrasse, Germany) 20080101 |
| Chlorido-, aqua-, 9-ethylguanine- and 9-ethyladenine-adducts of cytotoxic ruthenium arene complexes containing O,O-chelating ligands. | Journal of inorganic biochemistry 20071101 |
| Bifunctional amine-tethered ruthenium(II) arene complexes form monofunctional adducts on DNA. | Inorganic chemistry 20071015 |
| The mid-IR spectra of 9-ethyl guanine, guanosine, and 2-deoxyguanosine. | The journal of physical chemistry. A 20070809 |
| Interaction between the DNA model base 9-ethylguanine and a group of ruthenium polypyridyl complexes: kinetics and conformational temperature dependence. | Inorganic chemistry 20070806 |
| Structure of radicals from X-irradiated guanine derivatives. 2. An experimental and computational study of 9-ethylguanine single crystals. | The journal of physical chemistry. B 20070712 |
| Determination of aciclovir and ganciclovir in human plasma by liquid chromatography-spectrofluorimetric detection and stability studies in blood samples. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601 |
| Chloro half-sandwich osmium(II) complexes: influence of chelated N,N-ligands on hydrolysis, guanine binding, and cytotoxicity. | Inorganic chemistry 20070514 |
| Interguanine hydrogen-bonding patterns in adducts with water and Zn-purine complexes (purine is 9-methyladenine and 9-methylguanine). Unexpected preference of Zn(II) for adenine-N7 over guanine-N7. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070501 |
| Tuning the hydrolytic aqueous chemistry of osmium arene complexes with N,O-chelating ligands to achieve cancer cell cytotoxicity. | Journal of the American Chemical Society 20070321 |
| Osmium(II) and ruthenium(II) arene maltolato complexes: rapid hydrolysis and nucleobase binding. | Chemistry (Weinheim an der Bergstrasse, Germany) 20070101 |
| Dirhodium(II,II) complexes: molecular characteristics that affect in vitro activity. | Journal of medicinal chemistry 20061116 |
| Multiple metal binding to 6-oxopurine nucleobases as a source of deprotonation. The role of metal ions at N7 and N3. | Dalton transactions (Cambridge, England : 2003) 20060828 |
| Head-to-head cross-linked adduct between the antitumor unit bis(mu-N,N'-di-p-tolylformamidinato)dirhodium(II,II) and the DNA fragment d(GpG). | Chemistry (Weinheim an der Bergstrasse, Germany) 20060825 |
| The neglected Pt-N(sulfonamido) bond in Pt chemistry. New fluorophore-containing Pt(II) complexes useful for assessing Pt(II) interactions with biomolecules. | Inorganic chemistry 20060821 |
| Covalent and noncovalent interactions for [metal(dien)nucleobase](2+) complexes with L-tryptophan derivatives: formation of palladium-tryptophan species by nucleobase substitution under biologically relevant conditions. | Inorganic chemistry 20060220 |
| Tuning the reactivity of osmium(II) and ruthenium(II) arene complexes under physiological conditions. | Journal of the American Chemical Society 20060208 |
| cis-[Rh2(mu-O2CCH3)2(CH3CN)6]2+ as a photoactivated cisplatin analog. | Journal of the American Chemical Society 20060125 |
| G-G base-pairing in nucleobase adducts of the anticancer drug cis-[PtCl2(NH3)(2-picoline)] and its trans isomer. | Chemistry (Weinheim an der Bergstrasse, Germany) 20050718 |
| Cationic tetrakis(nucleobase)complexes of PtII as metalloligands and potential building blocks for molecular architectures. | Dalton transactions (Cambridge, England : 2003) 20050505 |
| Model platinum nucleobase and nucleoside complexes and antitumor activity: X-ray crystal structure of [PtIV(trans-1R,2R-diaminocyclohexane)trans-(acetate)2(9-ethylguanine)Cl]NO3.H2O. | Journal of inorganic biochemistry 20050301 |
| Photoinitiated DNA Binding by cis-[Ru(bpy)2(NH3)2]2+. | Inorganic chemistry 20041115 |
| A highly flexible dinuclear ruthenium(II)-platinum(II) complex: crystal structure and binding to 9-ethylguanine. | Angewandte Chemie (International ed. in English) 20041025 |
| Coordination of 9-ethylguanine to the mixed-ligand compound alpha-[Ru(azpy)(bpy)Cl2] (azpy = 2-phenylazopyridine and bpy = 2,2'-bipyridine). An unprecedented ligand positional shift, correlated to the cytotoxicity of this type of [RuL2Cl2] (with L = azpy or bpy) complex. | Inorganic chemistry 20040809 |
| Reactions of 9-substituted guanines with bromomalondialdehyde in aqueous solution predominantly yield glyoxal-derived adducts. | Organic & biomolecular chemistry 20040707 |
| Unprecedented head-to-head conformers of d(GpG) bound to the antitumor active compound tetrakis (mu-carboxylato)dirhodium(II,II). | Journal of the American Chemical Society 20030903 |
| Novel binding interactions of the DNA fragment d(pGpG) cross-linked by the antitumor active compound tetrakis(mu-carboxylato)dirhodium(II,II). | Journal of the American Chemical Society 20030903 |
| Intrinsic acid-base properties of purine derivatives in aqueous solution and comparison of the acidifying effects of platinum(II) coordinated to N1 or N7: acidifying effects are reciprocal and the proton 'outruns' divalent metal ions. | Inorganic chemistry 20030113 |
| Simultaneous N7,O6-binding of guanine to two zinc centers and its possible biological significance. | Inorganic chemistry 20021007 |
| A novel isomerization on interaction of antitumor-active azole-bridged dinuclear platinum(II) complexes with 9-ethylguanine. Platinum(II) atom migration from N2 to N3 on 1,2,3-triazole. | Journal of the American Chemical Society 20020501 |
| Organometallic ruthenium(II) diamine anticancer complexes: arene-nucleobase stacking and stereospecific hydrogen-bonding in guanine adducts. | Journal of the American Chemical Society 20020327 |
| Metal-modified nucleobase sextet: joining four linear metal fragments (trans-a2PtII) and six model nucleobases to an exceedingly stable entity. | Chemistry (Weinheim an der Bergstrasse, Germany) 20010504 |
| Alkylpurines as immunopotentiating agents. Synthesis and antiviral activity of certain alkylguanines. | Journal of medicinal chemistry 19931029 |