GPR30 Agonist, G-1
| Title | Journal |
|---|---|
| The G protein-coupled oestrogen receptor 1 agonist G-1 disrupts endothelial cell microtubule structure in a receptor-independent manner. | Molecular and cellular biochemistry 20120701 |
| Effects of a combined treatment with GPR30 agonist G-1 and herceptin on growth and gene expression of human breast cancer cell lines. | Cancer investigation 20120601 |
| Activation of GPR30 attenuates diastolic dysfunction and left ventricle remodelling in oophorectomized mRen2.Lewis rats. | Cardiovascular research 20120401 |
| Aberrant ligand-induced activation of G protein-coupled estrogen receptor 1 (GPER) results in developmental malformations during vertebrate embryogenesis. | Toxicological sciences : an official journal of the Society of Toxicology 20120101 |
| G protein-coupled estrogen receptor 1-mediated effects in the rat myometrium. | American journal of physiology. Cell physiology 20111101 |
| Estrogen receptor GPR30 reduces oxidative stress and proteinuria in the salt-sensitive female mRen2.Lewis rat. | Hypertension (Dallas, Tex. : 1979) 20111001 |
| Induction of interleukin-10 in the T helper type 17 effector population by the G protein coupled estrogen receptor (GPER) agonist G-1. | Immunology 20110901 |
| Mechanisms of estradiol-induced insulin secretion by the G protein-coupled estrogen receptor GPR30/GPER in pancreatic beta-cells. | Endocrinology 20110801 |
| Insulinotropic and antidiabetic effects of 17β-estradiol and the GPR30 agonist G-1 on human pancreatic islets. | Endocrinology 20110701 |
| Estrogen destabilizes microtubules through an ion-conductivity-independent TRPV1 pathway. | Journal of neurochemistry 20110601 |
| Vasodilation in response to the GPR30 agonist G-1 is not different from estradiol in the mRen2.Lewis female rat. | Journal of cardiovascular pharmacology 20110501 |
| GPR30 activation opposes estrogen-dependent uterine growth via inhibition of stromal ERK1/2 and estrogen receptor alpha (ERα) phosphorylation signals. | Endocrinology 20110401 |
| GPR30 co-localizes with cholinergic neurons in the basal forebrain and enhances potassium-stimulated acetylcholine release in the hippocampus. | Psychoneuroendocrinology 20110201 |
| The GPER1 agonist G-1 attenuates endothelial cell proliferation by inhibiting DNA synthesis and accumulating cells in the S and G2 phases of the cell cycle. | Journal of vascular research 20110101 |
| Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21, and induction of G(2) cell-cycle arrest. | Cell death and differentiation 20100901 |
| Signaling via GPR30 protects the myocardium from ischemia/reperfusion injury. | Surgery 20100801 |
| Expression and signaling of G protein-coupled estrogen receptor 1 (GPER) in rat sertoli cells. | Biology of reproduction 20100801 |
| Dilation of epicardial coronary arteries by the G protein-coupled estrogen receptor agonists G-1 and ICI 182,780. | Pharmacology 20100801 |
| Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs. | Organic & biomolecular chemistry 20100507 |
| Regulation of ERRalpha gene expression by estrogen receptor agonists and antagonists in SKBR3 breast cancer cells: differential molecular mechanisms mediated by g protein-coupled receptor GPR30/GPER-1. | Molecular endocrinology (Baltimore, Md.) 20100501 |
| Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries. | American journal of physiology. Heart and circulatory physiology 20100301 |
| The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells. | Cancer research 20100201 |
| Attenuation of salt-induced cardiac remodeling and diastolic dysfunction by the GPER agonist G-1 in female mRen2.Lewis rats. | PloS one 20100101 |
| Activation of a novel estrogen receptor, GPER, is cardioprotective in male and female rats. | American journal of physiology. Heart and circulatory physiology 20091101 |
| Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis. | Journal of neuroimmunology 20090929 |
| Chronic treatment with estrogen receptor agonists restores acquisition of a spatial learning task in young ovariectomized rats. | Hormones and behavior 20090901 |
| Chronic treatment with the G protein-coupled receptor 30 agonist G-1 decreases blood pressure in ovariectomized mRen2.Lewis rats. | Endocrinology 20090801 |
| Expression of estrogen receptor GPR30 in the rat spinal cord and in autonomic and sensory ganglia. | Journal of neuroscience research 20090515 |
| Involvement of estradiol-17beta and its membrane receptor, G protein coupled receptor 30 (GPR30) in regulation of oocyte maturation in zebrafish, Danio rario. | General and comparative endocrinology 20090301 |
| Membrane estrogen receptor regulates experimental autoimmune encephalomyelitis through up-regulation of programmed death 1. | Journal of immunology (Baltimore, Md. : 1950) 20090301 |
| GPR30 estrogen receptor agonists induce mechanical hyperalgesia in the rat. | The European journal of neuroscience 20080401 |
| GPR30 contributes to estrogen-induced thymic atrophy. | Molecular endocrinology (Baltimore, Md.) 20080301 |
| Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system. | The Journal of endocrinology 20070501 |
| G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells. | Cancer research 20070215 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |