(5S,8S,14S,17S,20S)-14,17-Dibenzyl-5-carbamoyl-20-(carboxymethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
| Title | Journal |
|---|---|
| Neurokinin B and the control of the gonadotropic axis in the rat: developmental changes, sexual dimorphism, and regulation by gonadal steroids. | Endocrinology 20121001 |
| The NK3 receptor agonist senktide ameliorates scopolamine-induced deficits in memory for object, place and temporal order. | Neurobiology of learning and memory 20120201 |
| Kisspeptin signaling is indispensable for neurokinin B, but not glutamate, stimulation of gonadotropin secretion in mice. | Endocrinology 20120101 |
| Activation of neurokinin 3 receptors in the median preoptic nucleus decreases core temperature in the rat. | Endocrinology 20111201 |
| NK3 receptors mediate an increase in firing rate of midbrain dopamine neurons of the rat and the guinea pig. | Synapse (New York, N.Y.) 20110801 |
| Neurokinin3-R agonism in aged rats has anxiolytic-, antidepressant-, and promnestic-like effects and stimulates ACh release in frontal cortex, amygdala and hippocampus. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20110601 |
| Interactions between kisspeptin and neurokinin B in the control of GnRH secretion in the female rat. | American journal of physiology. Endocrinology and metabolism 20110101 |
| Blockade of tachykinin NK3 receptor reverses hypertension through a dopaminergic mechanism in the ventral tegmental area of spontaneously hypertensive rats. | British journal of pharmacology 20101201 |
| Bronchoconstrictor effect of the tachykinin NK₃-receptor agonists [MePhe⁷]-neurokinin B and senktide in the isolated guinea pig lung. | Experimental lung research 20101101 |
| Neurokinin B acts via the neurokinin-3 receptor in the retrochiasmatic area to stimulate luteinizing hormone secretion in sheep. | Endocrinology 20100801 |
| In vitro and in vivo comparison of two non-peptide tachykinin NK3 receptor antagonists: Improvements in efficacy achieved through enhanced brain penetration or altered pharmacological characteristics. | European journal of pharmacology 20100210 |
| Pharmacological characterization of senktide-induced tail whips. | Neuropharmacology 20100101 |
| Hypogonadotropic hypogonadism due to a novel missense mutation in the first extracellular loop of the neurokinin B receptor. | The Journal of clinical endocrinology and metabolism 20091001 |
| Activation of neurokinin 3 receptor increases Na(v)1.9 current in enteric neurons. | The Journal of physiology 20090401 |
| The tachykinin NK3 receptor agonist senktide induces locomotor activity in male Mongolian gerbils. | European journal of pharmacology 20081214 |
| Localization and function of NK(3) subtype tachykinin receptors of layer V pyramidal neurons of the guinea-pig medial prefrontal cortex. | Neuroscience 20081028 |
| Characterization of behavioral response to amphetamine, tyrosine hydroxylase levels, and dopamine receptor levels in neurokinin 3 receptor knockout mice. | Behavioural pharmacology 20080901 |
| Neurokinin B/NK3 receptors exert feedback inhibition on L-DOPA actions in the 6-OHDA lesion rat model of Parkinson's disease. | Neuropharmacology 20080601 |
| Neurokinin receptor modulation of respiratory activity in the rabbit. | The European journal of neuroscience 20080601 |
| Stimulation of the neurokinin 3 receptor activates protein kinase C epsilon and protein kinase D in enteric neurons. | American journal of physiology. Gastrointestinal and liver physiology 20080501 |
| Neurokinin-3 peptide instead of neurokinin-1 synergistically exacerbates kainic acid-inducing degeneration of neurons in the substantia nigra of mice. | Journal of neurochemistry 20080401 |
| Expression and coupling of neurokinin receptor subtypes to inositol phosphate and calcium signaling pathways in human airway smooth muscle cells. | American journal of physiology. Lung cellular and molecular physiology 20080301 |
| Contractile effect of tachykinins on Suncus murinus (house musk shrew) isolated ileum. | Neuropeptides 20080101 |
| Senktide-induced gerbil foot tapping behaviour is blocked by selective tachykinin NK1 and NK3 receptor antagonists. | European journal of pharmacology 20071222 |
| Inflammation and inflammatory agents activate protein kinase C epsilon translocation and excite guinea-pig submucosal neurons. | Gastroenterology 20071001 |
| Neurokinin 3 receptor activation potentiates the psychomotor and nucleus accumbens dopamine response to cocaine, but not its place conditioning effects. | The European journal of neuroscience 20070401 |
| N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists II. | Bioorganic & medicinal chemistry letters 20061115 |
| Interaction of the tachykinin NK3 receptor agonist senktide with behavioral effects of cocaine in marmosets (Callithrix penicillata). | Peptides 20060901 |
| The role of tachykinins in circular muscle contractility of the murine ileum: a functional investigation. | Autonomic neuroscience : basic & clinical 20060630 |
| Upregulation of tachykinin NK-1 and NK-3 receptor binding sites in the spinal cord of spontaneously hypertensive rat: impact on the autonomic control of blood pressure. | British journal of pharmacology 20060501 |
| Increased substance P content in nerve fibers associated with mesenteric veins from deoxycorticosterone acetate (DOCA)-salt hypertensive rats. | Regulatory peptides 20060115 |
| Intraventricular injections of tachykinin NK3 receptor agonists suppress the intake of 'salty' tastes by sodium deficient rats. | Behavioural brain research 20060106 |
| The ventral tegmental area as a putative target for tachykinins in cardiovascular regulation. | British journal of pharmacology 20050701 |
| Loperamide inhibits tachykinin NK3-receptor-triggered serotonin release without affecting NK2-receptor-triggered serotonin release from guinea pig colonic mucosa. | Journal of pharmacological sciences 20050601 |
| Intraventricular injections of tachykinin NK3 receptor agonist reduce the gain of the baroreflex in unrestrained rats. | Experimental neurology 20050501 |
| A novel role for tachykinin neurokinin-3 receptors in regulation of human bronchial Ganglia neurons. | American journal of respiratory and critical care medicine 20050201 |
| Slow excitatory post-synaptic potentials in myenteric AH neurons of the guinea-pig ileum are reduced by the 5-hydroxytryptamine7 receptor antagonist SB 269970. | Neuroscience 20050101 |
| Role of neurokinin 3 receptors in supraoptic vasopressin and oxytocin neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20041110 |
| Involvement of enhanced neurokinin NK3 receptor expression in the severe asthma guinea pig model. | European journal of pharmacology 20040913 |
| GABAergic basal forebrain neurons that express receptor for neurokinin B and send axons to the cerebral cortex. | The Journal of comparative neurology 20040517 |
| Effects of TAK-637 on NK(1) receptor-mediated mechanisms regulating colonic secretion. | Toxicology and applied pharmacology 20040415 |
| NK-3 receptor activation depolarizes and induces an after-depolarization in pyramidal neurons in gerbil cingulate cortex. | Brain research bulletin 20040315 |
| Effects of neuropeptides on the sumatriptan-disturbed circulation in the optic nerve head of rabbits. | Pharmacology 20040301 |
| Neurokinin-1 and -3 receptor blockade inhibits slow excitatory synaptic transmission in myenteric neurons and reveals slow inhibitory input. | Neuroscience 20040101 |
| Neurokinin type-3 receptor stimulation impairs ethanol-associated appetitive behavior in Wistar rats. | Alcoholism, clinical and experimental research 20031201 |
| Central neurokinin 3 receptors increase systemic oxytocin release: interaction with norepinephrine. | Experimental neurology 20031201 |
| The new neurokinin 1-sensitive receptor mediates the facilitation by endogenous tachykinins of the NMDA-evoked release of acetylcholine after suppression of dopaminergic transmission in the matrix of the rat striatum. | Journal of neurochemistry 20031001 |
| Tachykinin receptor (NK(1), NK(2), NK(3)) binding sites in the rat caudal brainstem following neonatal capsaicin administration. | Brain research 20030725 |
| Action of tachykinins in the rat hippocampus: modulation of inhibitory synaptic transmission. | The European journal of neuroscience 20030601 |
| Estrogen-dependent regulation of neurokinin 3 receptor-mediated uterine contractility in the rat. | Biology of reproduction 20021101 |
| Neurokinin-receptor-mediated depolarization of cortical neurons elicits an increase in glutamate release at excitatory synapses. | The European journal of neuroscience 20021101 |
| Neurokinins activate local glutamatergic inputs to serotonergic neurons of the dorsal raphe nucleus. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20020901 |
| Endogenous neurokinins facilitate synaptic transmission in guinea pig airway parasympathetic ganglia. | American journal of physiology. Regulatory, integrative and comparative physiology 20020801 |
| Biochemical and pharmacological activities of SSR 146977, a new potent nonpeptide tachykinin NK3 receptor antagonist. | Canadian journal of physiology and pharmacology 20020501 |
| Selective tachykinin NK3-receptor agonists stimulate in vitro exocrine pancreatic secretion in the guinea pig. | Peptides 20020501 |
| Peripheral activity of a new NK1 receptor antagonist TAK-637 in the gastrointestinal tract. | The Journal of pharmacology and experimental therapeutics 20020301 |
| Facilitation by endogenous tachykinins of the NMDA-evoked release of acetylcholine after acute and chronic suppression of dopaminergic transmission in the matrix of the rat striatum. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020301 |
| Permissive role of neurokinin NK(3) receptors in NK(1) receptor-mediated activation of the locus coeruleus revealed by SR 142801. | Synapse (New York, N.Y.) 20020101 |
| Nonpeptide tachykinin receptor antagonists. III. SB 235375, a low central nervous system-penetrant, potent and selective neurokinin-3 receptor antagonist, inhibits citric acid-induced cough and airways hyper-reactivity in guinea pigs. | The Journal of pharmacology and experimental therapeutics 20020101 |
| Neuronal bursting induced by NK3 receptor activation in the neonatal rat spinal cord in vitro. | Journal of neurophysiology 20011201 |
| Modulation of cardiac activity by tachykinins in the rat substantia nigra. | British journal of pharmacology 20011201 |
| Radioligand binding and functional characterisation of tachykinin receptors in chicken small intestine. | Naunyn-Schmiedeberg's archives of pharmacology 20011001 |
| Tachykinins mediate slow excitatory postsynaptic transmission in guinea pig sphincter of Oddi ganglia. | American journal of physiology. Gastrointestinal and liver physiology 20010801 |
| Peripheral inflammation reduces the response of spinal dorsal horn neurons to an NK3 receptor agonist. | Neuroscience letters 20010727 |
| Pharmacological characterization of ZD6021: a novel, orally active antagonist of the tachykinin receptors. | The Journal of pharmacology and experimental therapeutics 20010701 |
| Priming effects of substance P on calcium changes evoked by interleukin-8 in human neutrophils. | Journal of leukocyte biology 20010601 |
| Contribution of NK3 tachykinin receptors to propulsion in the rabbit isolated distal colon. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20010601 |
| Differential expression of functionally identified and immunohistochemically identified NK(1) receptors on sympathetic neurons. | Journal of neurophysiology 20010501 |
| Potent NK1 antagonism by SR-140333 reduces rat colonic secretory response to immunocyte activation. | American journal of physiology. Cell physiology 20010401 |
| Molecular and pharmacological characterization of the murine tachykinin NK(3) receptor. | European journal of pharmacology 20010216 |
| NK2 tachykinin receptors mediate contraction of the pig intravesical ureter: tachykinin-induced enhancement of non-adrenergic non-cholinergic excitatory neurotransmission. | Neurourology and urodynamics 20010101 |
| Nonpeptide tachykinin receptor antagonists. II. Pharmacological and pharmacokinetic profile of SB-222200, a central nervous system penetrant, potent and selective NK-3 receptor antagonist. | The Journal of pharmacology and experimental therapeutics 20001001 |
| Nonpeptide tachykinin receptor antagonists: I. Pharmacological and pharmacokinetic characterization of SB 223412, a novel, potent and selective neurokinin-3 receptor antagonist. | The Journal of pharmacology and experimental therapeutics 19970601 |
| The unpredicted high affinities of a large number of naturally occurring tachykinins for chimeric NK1/NK3 receptors suggest a role for an inhibitory domain in determining receptor specificity. | The Journal of biological chemistry 19960823 |
| 2-Phenyl-4-quinolinecarboxamides: a novel class of potent and selective non-peptide competitive antagonists for the human neurokinin-3 receptor. | Journal of medicinal chemistry 19960607 |
| Use of a dipeptide chemical library in the development of non-peptide tachykinin NK3 receptor selective antagonists. | Journal of medicinal chemistry 19960412 |
| GR138676, a novel peptidic tachykinin antagonist which is potent at NK3 receptors. | Neuropeptides 19941201 |
| Molecular characterisation, expression and localisation of human neurokinin-3 receptor. | FEBS letters 19920324 |
| Highly selective agonists for substance P receptor subtypes. | The EMBO journal 19861101 |
| Characterization of a neurokinin B receptor site in rat brain using a highly selective radioligand. | The Journal of biological chemistry 19860805 |