2-Piperidinecarboxylicacid, 4-(phosphonomethyl)-, (2R,4S)-rel-
| Title | Journal |
|---|---|
| A review of neuroprotection pharmacology and therapies in patients with acute traumatic brain injury. | CNS drugs 20120701 |
| Pre-synaptic glycine GlyT1 transporter--NMDA receptor interaction: relevance to NMDA autoreceptor activation in the presence of Mg2+ ions. | Journal of neurochemistry 20110501 |
| Pathophysiology, treatment, and animal and cellular models of human ischemic stroke. | Molecular neurodegeneration 20110101 |
| Cerebral perfusion pressure, microdialysis biochemistry and clinical outcome in patients with traumatic brain injury. | BMC research notes 20110101 |
| Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: design, synthesis, and structure-activity relationships. | Bioorganic & medicinal chemistry 20101101 |
| Integrative emphases on intimate, intrinsic propensity/pathological processes--causes of self recovery limits and also, subtle related targets for neuroprotectionl pleiotropicity/multimodal actions, by accessible therapeutic approaches--in spinal cord injuries. | Journal of medicine and life 20100815 |
| Resistin is associated with mortality in patients with traumatic brain injury. | Critical care (London, England) 20100101 |
| NMDA-mediated modulation of dopamine release is modified in rat prefrontal cortex and nucleus accumbens after chronic nicotine treatment. | Journal of neurochemistry 20090101 |
| Molecular mechanisms of traumatic brain injury: the missing link in management. | World journal of emergency surgery : WJES 20090101 |
| Cerebral vasospasm following traumatic subarachnoid hemorrhage. | Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20090101 |
| Risks associated with magnetic resonance imaging and cervical collar in comatose, blunt trauma patients with negative comprehensive cervical spine computed tomography and no apparent spinal deficit. | Critical care (London, England) 20080101 |
| Pharmacology of traumatic brain injury: where is the 'golden bullet'? | Molecular medicine (Cambridge, Mass.) 20080101 |
| Repeated treatment with N-methyl-d-aspartate antagonists in neonatal, but not adult, rats causes long-term deficits of radial-arm maze learning. | Brain research 20070912 |
| Increased cerebral oxygen consumption in Eker rats and effects of N-methyl-D-aspartate blockade: Implications for autism. | Journal of neuroscience research 20070815 |
| Intracranial pressure monitoring in intensive care: clinical advantages of a computerized system over manual recording. | Critical care (London, England) 20070101 |
| NMDA receptor activity in learning spatial procedural strategies I. The influence of hippocampal lesions. | Brain research bulletin 20061016 |
| NMDA receptor activity in learning spatial procedural strategies II. The influence of cerebellar lesions. | Brain research bulletin 20061016 |
| Acute D2/D3 dopaminergic agonism but chronic D2/D3 antagonism prevents NMDA antagonist neurotoxicity. | Biological psychiatry 20060915 |
| Neuroprotection associated with alternative splicing of NMDA receptors in rat cortical neurons. | British journal of pharmacology 20060301 |
| Some prognostic models for traumatic brain injury were not valid. | Journal of clinical epidemiology 20060201 |
| The NMDA receptor antagonist CGS 19755 disrupts recovery following cerebellar lesions. | Restorative neurology and neuroscience 20060101 |
| Glutamate receptors in neuroinflammatory demyelinating disease. | Mediators of inflammation 20060101 |
| Severe brain injury ICU outcomes are associated with Cranial-Arterial Pressure Index and noninvasive Bispectral Index and transcranial oxygen saturation: a prospective, preliminary study. | Critical care (London, England) 20060101 |
| 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization. | Journal of medicinal chemistry 20051103 |
| Methodological quality of animal studies on neuroprotection in focal cerebral ischaemia. | Journal of neurology 20050901 |
| Development of a three-dimensional model for the N-methyl-D-aspartate NR2A subunit. | Journal of medicinal chemistry 20050825 |
| Cognitive effects of dopaminergic and glutamatergic blockade in nucleus accumbens in pigeons. | Pharmacology, biochemistry, and behavior 20050801 |
| Homocysteine, a risk factor for atherosclerosis, biphasically changes the endothelial production of kynurenic acid. | European journal of pharmacology 20050711 |
| Effects of the N-methyl-D-aspartate receptor antagonist perzinfotel [EAA-090; [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)-ethyl]phosphonic acid] on chemically induced thermal hypersensitivity. | The Journal of pharmacology and experimental therapeutics 20050601 |
| The NMDA receptor complex: a long and winding road to therapeutics. | IDrugs : the investigational drugs journal 20050301 |
| Cerebral perfusion pressure and risk of brain hypoxia in severe head injury: a prospective observational study. | Critical care (London, England) 20050101 |
| Acute nociceptive somatic stimulus sensitizes neurones in the spinal cord to colonic distension in the rat. | The Journal of physiology 20041001 |
| Neuroprotection against ischemic/hypoxic brain damage: blockers of ionotropic glutamate receptor and voltage sensitive calcium channels. | Current drug targets 20041001 |
| Nicotine exerts a permissive role on NMDA receptor function in hippocampal noradrenergic terminals. | Neuropharmacology 20040701 |
| The rise and fall of NMDA antagonists for ischemic stroke. | Current molecular medicine 20040301 |
| Lessons from epidemiologic studies in clinical trials of traumatic brain injury. | Acta neurochirurgica. Supplement 20040101 |
| NMDA-evoked consumption and recovery of mitochondrially targeted aequorin suggests increased Ca2+ uptake by a subset of mitochondria in hippocampal neurons. | Brain research 20031212 |
| Cannabinoid CB1 receptor activation does not prevent the toxicity of glutamate towards embryonic chick telencephalon primary cultures. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20031101 |
| Neuroprotective effects of N-methyl-D-aspartate receptor antagonist on aspartate induced neurotoxicity in the spinal cord in vivo. | The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi 20031001 |
| Glutamate receptor antagonists modulate heat shock protein response in focal brain ischemia. | Neurological research 20030301 |
| Stroke: trial by jury. | European neurology 20030101 |
| Excitatory amino acid antagonists for acute stroke. | The Cochrane database of systematic reviews 20030101 |
| Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury? | The Lancet. Neurology 20021001 |
| Multisubstrate analogue inhibitors of glucosamine-6-phosphate synthase from Candida albicans. | Bioorganic & medicinal chemistry letters 20020916 |
| Neuroprotective agents in acute ischemic stroke. | The Journal of the Association of Physicians of India 20020201 |
| Antiepileptic drugs and agents that inhibit voltage-gated sodium channels prevent NMDA antagonist neurotoxicity. | Molecular psychiatry 20020101 |
| Glutamate AMPA receptor antagonist treatment for ischaemic stroke. | Current medical research and opinion 20020101 |
| Effects of antagonism of NMDA receptors on transient lower esophageal sphincter relaxations in the dog. | European journal of pharmacology 20011116 |
| Design, synthesis, SAR, and biological evaluation of highly potent benzimidazole-spaced phosphono-alpha-amino acid competitive NMDA antagonists of the AP-6 type. | Journal of medicinal chemistry 20010510 |
| A comparative assessment of the efficacy and side-effect liability of neuroprotective compounds in experimental stroke. | Brain research 20010223 |
| Regional distribution and pharmacological characteristics of [3H]N-acetyl-aspartyl-glutamate (NAAG) binding sites in rat brain. | Neurochemistry international 20010101 |
| The 26th Congress of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine, Tromso, Norway, 13-17 June 2001. | Critical care (London, England) 20010101 |
| Anticonvulsant efficacy of N-methyl-D-aspartate antagonists against convulsions induced by cocaine. | The Journal of pharmacology and experimental therapeutics 19990501 |
| NMDA antagonists potentiate scopolamine-induced amnesic effect. | Behavioural brain research 19970201 |
| Glutamatergic antagonism: effects on lidocaine-induced seizures in the rat. | Anesthesia and analgesia 19941001 |
| Yohimbine-induced seizures involve NMDA and GABAergic transmission. | Neuropharmacology 19920401 |