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Mivacurium Chloride

CAS No.:
106861-44-3
Catalog Number:
AG0082VI
Molecular Formula:
C28H40NO7+
Molecular Weight:
502.6197
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
10mg
95%
In Stock USA
United States
$226
- +
25mg
95%
In Stock USA
United States
$433
- +
100mg
95%
In Stock USA
United States
$1339
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Product Description
Catalog Number:
AG0082VI
Chemical Name:
Mivacurium Chloride
CAS Number:
106861-44-3
Molecular Formula:
C28H40NO7+
Molecular Weight:
502.6197
MDL Number:
MFCD00867767
IUPAC Name:
bis[3-[(1R)-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] (E)-oct-4-enedioate;dichloride
InChI:
InChI=1S/C58H80N2O14.2ClH/c1-59(25-21-41-35-47(63-3)49(65-5)37-43(41)45(59)29-39-31-51(67-7)57(71-11)52(32-39)68-8)23-17-27-73-55(61)19-15-13-14-16-20-56(62)74-28-18-24-60(2)26-22-42-36-48(64-4)50(66-6)38-44(42)46(60)30-40-33-53(69-9)58(72-12)54(34-40)70-10;;/h13-14,31-38,45-46H,15-30H2,1-12H3;2*1H/q+2;;/p-2/b14-13+;;/t45-,46-,59?,60?;;/m1../s1
InChI Key:
WMSYWJSZGVOIJW-ONUALHDOSA-L
SMILES:
CCC(=O)OCCC[N+]1(C)CCc2c([C@H]1Cc1cc(OC)c(c(c1)OC)OC)cc(c(c2)OC)OC
UNII:
600ZG213C3
Properties
Complexity:
1550  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
1  
Exact Mass:
1098.499g/mol
Formal Charge:
0
Heavy Atom Count:
76  
Hydrogen Bond Acceptor Count:
16  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
1100.178g/mol
Monoisotopic Mass:
1098.499g/mol
Rotatable Bond Count:
30  
Topological Polar Surface Area:
145A^2
Undefined Atom Stereocenter Count:
2  
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
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Onset and duration of mivacurium-induced neuromuscular block in patients with Duchenne muscular dystrophy. British journal of anaesthesia 20051201
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The identification of mivacurium and metabolites in biological samples. Journal of analytical toxicology 20051001
Effects of mivacurium on the diaphragm evaluated by cervical magnetic stimulation of the phrenic nerves. European journal of anaesthesiology 20050701
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Time course and train-of-four fade of mivacurium block during sevoflurane and intravenous anaesthesia. European journal of anaesthesiology 20050401
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Prolonged paralysis following mivacurium administration. Anaesthesia and intensive care 20020601
Anesthesia for electroconvulsive therapy. Anesthesia and analgesia 20020501
The pharmacodynamics and pharmacokinetics of mivacurium in children. Acta anaesthesiologica Scandinavica 20020501
A comparison of neuromuscular effects, tracheal intubating conditions, and reversibility of rapacuronium versus mivacurium in female patients. Anesthesia and analgesia 20020401
Allergic reactions occurring during anaesthesia. European journal of anaesthesiology 20020401
Muscle relaxation does not alter hypnotic level during propofol anesthesia. Anesthesia and analgesia 20020301
The relationship between acceleromyographic train-of-four fade and single twitch depression. Anesthesiology 20020301
Isobolographic analysis of non-depolarising muscle relaxant interactions at their receptor site. European journal of pharmacology 20020301
Phonomyography of the corrugator supercilii muscle: signal characteristics, best recording site and comparison with acceleromyography. British journal of anaesthesia 20020301
Screening patients with prolonged neuromuscular blockade after succinylcholine and mivacurium. Anesthesia and analgesia 20020201
Role of endogenous histamine in altered lung mechanics in rabbits. Anesthesiology 20020201
Effect of metoclopramide on mivacurium-induced neuromuscular block. Acta anaesthesiologica Scandinavica 20020201
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Equi-lasting doses of rocuronium, compared to mivacurium, result in improved neuromuscular blockade in patients undergoing gynecological laparoscopy : [Des doses de durée équivalente de rocuronium, comparé au mivacurium, améliorent la curarisation chez des patientes qui subissent une laparoscopie gynécologique]. Canadian journal of anaesthesia = Journal canadien d'anesthesie 20011201
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Magnesium as part of balanced general anaesthesia with propofol, remifentanil and mivacurium: a double-blind, randomized prospective study in 50 patients. European journal of anaesthesiology 20011101
Total intravenous anaesthesia in a patient with familial hypokalaemic periodic paralysis. Anaesthesia 20011101
The influence of atracurium, cisatracurium, and mivacurium on the proliferation of two human cell lines in vitro. Anesthesia and analgesia 20010901
Response to mivacurium in a patient compound heterozygous for a novel and a known silent mutation in the butyrylcholinesterase gene: genotyping by sequencing. Anesthesiology 20010901
In vitro effects of fluoride on pseudocholinesterase activity and the metabolism of the cis-trans and trans-trans isomers of mivacurium. Anesthesiology 20010901
Sensitivity of action potential triggering is normally distributed as a function of mean fractional receptor activation. Anaesthesia and intensive care 20010801
Succinylcholine pretreatment using gallamine or mivacurium during rapid sequence induction in children: a randomized, controlled study. Journal of clinical anesthesia 20010601
Peripheral link model as an alternative for pharmacokinetic-pharmacodynamic modeling of drugs having a very short elimination half-life. Journal of pharmacokinetics and pharmacodynamics 20010201
Reversal of mivacurium-induced neuromuscular block by neostigmine. Middle East journal of anaesthesiology 20010201
Intramuscular versus surface electromyography of the diaphragm for determining neuromuscular blockade. Anesthesia and analgesia 20010101
No substitute for the intravenous route. Anesthesiology 20010101
[Effects of non-depolarizing muscle relaxants on the duration of mivacurium]. Acta cientifica venezolana 20010101
Recent advances in myorelaxant therapy. Paediatric anaesthesia 20010101
Muscle relaxants suitable for day case surgery. European journal of anaesthesiology. Supplement 20010101
Muscle relaxants in paediatric day case surgery. European journal of anaesthesiology. Supplement 20010101
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Is succinylcholine after pretreatment with d-tubocurarine and lidocaine contraindicated for outpatient anesthesia? Anesthesia and analgesia 20000801
Intubation conditions and postoperative myalgia in outpatient dental surgery: a comparison of succinylcholine with mivacurium. Anaesthesia and intensive care 20000401
Organophosphorus pesticide-induced butyrylcholinesterase inhibition and potentiation of succinylcholine toxicity in mice. Journal of biochemical and molecular toxicology 19990101
Suxamethonium and mivacurium sensitivity from pregnancy-induced plasma cholinesterase deficiency. Anaesthesia 19981101
The effect of mivacurium pretreatment on intra-ocular pressure changes induced by suxamethonium. Anaesthesia 19980501
Potentiation of mivacurium by rocuronium is age- and time-dependent: a study in children, adolescents, and young and elderly adults. Journal of clinical pharmacology 19970701
Markedly prolonged paralysis after mivacurium in a patient apparently heterozygous for the atypical and usual pseudocholinesterase alleles by conventional biochemical testing. Anesthesia and analgesia 19970201
Clinical pharmacology of mivacurium chloride: a review. Journal of clinical anesthesia 19920101
Properties