6-Fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4h-(1,3)thiazeto(3,2-a)quinoline-3-carboxylic acid
Title | Journal |
---|---|
Penetration of prulifloxacin into sinus mucosa of patients undergoing paranasal sinus elective endoscopic surgery. | Journal of chemotherapy (Florence, Italy) 20120201 |
Prulifloxacin versus levofloxacin in the treatment of respiratory and urinary tract infections: a multicentre, double-blind, randomized controlled clinical trial. | Chemotherapy 20120101 |
Antipneumococcal activity of ulifloxacin compared to levofloxacin and ciprofloxacin. | Journal of chemotherapy (Florence, Italy) 20111001 |
Development and validation of a liquid chromatography-tandem mass spectrometry method to determine ulifloxacin, the active metabolite of prulifloxacin in rat and rabbit plasma: application to toxicokinetic study. | Biomedical chromatography : BMC 20110801 |
Synthesis and evaluation of 1-cyclopropyl-2-thioalkyl-8-methoxy fluoroquinolones. | Bioorganic & medicinal chemistry letters 20110801 |
[In vitro synergism of ulifloxacin plus piperacillin/tazobactam against clinical isolates of Enterobacteriaceae producing extended-spectrum or AmpC-type β-lactamases]. | Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20101201 |
[Susceptibility surveillance of clinical isolates to fluoroquinolone antimicrobial agents from 2003 to 2008: post-marketing study of prulifloxacin]. | The Japanese journal of antibiotics 20100601 |
Human carboxymethylenebutenolidase as a bioactivating hydrolase of olmesartan medoxomil in liver and intestine. | The Journal of biological chemistry 20100416 |
Effects of prulifloxacin on cardiac repolarization in healthy subjects: a randomized, crossover, double-blind versus placebo, moxifloxacin-controlled study. | Clinical drug investigation 20100101 |
Active uptake of ulifloxacin from plasma to lung that controls its concentration in epithelial lining fluid. | Biological & pharmaceutical bulletin 20090601 |
Prulifloxacin: clinical studies of a broad-spectrum quinolone agent. | Future microbiology 20090201 |
Penetration of orally administered prulifloxacin into human prostate tissue. | Clinical drug investigation 20090101 |
Determination of ulifloxacin, the active metabolite of prulifloxacin, in human plasma by a 96-well format solid-phase extraction and capillary zone electrophoresis. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080901 |
Proposal of membrane transport mechanism of protein-unbound ulifloxacin into epithelial lining fluid determined by improved microdialysis. | Biological & pharmaceutical bulletin 20080901 |
Simultaneous determination of Ciprofloxacin and the active metabolite of Prulifloxacin in aqueous human humor by high-performance liquid chromatography. | Journal of pharmaceutical and biomedical analysis 20080715 |
Effects of fluoroquinolones on bacterial adhesion and on preformed biofilm of strains isolated from urinary double J stents. | Journal of chemotherapy (Florence, Italy) 20080401 |
Determination of ulifloxacin by terbium-sensitized fluorescence with second-order scattering and its applications. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20071201 |
Involvement of breast cancer resistance protein (ABCG2) in the biliary excretion mechanism of fluoroquinolones. | Drug metabolism and disposition: the biological fate of chemicals 20071001 |
Transporter-mediated hepatic uptake of ulifloxacin, an active metabolite of a prodrug-type new quinolone antibiotic prulifloxacin, in rats. | Drug metabolism and pharmacokinetics 20071001 |
Activity of ulifloxacin against clinical hospital isolates. | Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20070901 |
Prulifloxacin: a brief review of its potential in the treatment of acute exacerbation of chronic bronchitis. | International journal of chronic obstructive pulmonary disease 20070301 |
Penetration of prulifloxacin into gynaecological tissues after single and repeated oral administrations. | Drugs in R&D 20070101 |
Determination of the active metabolite of prulifloxacin in human plasma by liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060307 |
Prulifloxacin: a new antibacterial fluoroquinolone. | Expert review of anti-infective therapy 20060201 |
Prulifloxacin: a new fluoroquinolone for the treatment of acute exacerbation of chronic bronchitis. | Pulmonary pharmacology & therapeutics 20060101 |
Pharmacologic characteristics of prulifloxacin. | Pulmonary pharmacology & therapeutics 20060101 |
Synergistic effect of fosfomycin and fluoroquinolones against Pseudomonas aeruginosa growing in a biofilm. | Acta medica Okayama 20051001 |
Interpretive criteria for disk diffusion susceptibility testing of ulifloxacin, the active metabolite of prulifloxacin. | Journal of chemotherapy (Florence, Italy) 20050401 |
Penetration of orally administered prulifloxacin into human lung tissue. | Clinical pharmacokinetics 20050101 |
Molecular characterization of clinical Streptococcus pneumoniae isolates with reduced susceptibility to fluoroquinolones emerging in Italy. | Microbial drug resistance (Larchmont, N.Y.) 20040101 |
Prulifloxacin. | Drugs 20040101 |
[In vitro antibacterial activity of prulifloxacin, a new oral fluoroquinolone]. | The Japanese journal of antibiotics 20021201 |
[In vitro short-term bactericidal activity and accumulation of NM394, the active metabolite of prulifloxacin, for Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa: comparison with ciprofloxacin, levofloxacin, and gatifloxacin]. | The Japanese journal of antibiotics 20021201 |
[Inhibitory activity of NM394, the active form of prodrug prulifloxacin against type II topoisomerase from Pseudomonas aeruginosa]. | The Japanese journal of antibiotics 20021201 |
Therapeutic effect of the quinolone prodrug prulifloxacin against experimental urinary tract infections in mice. | Arzneimittel-Forschung 19961201 |
[In vitro antimycobacterial activity of a new quinolone, NM394]. | Kekkaku : [Tuberculosis] 19930801 |