Home Other Building Blocks Dicloxacillin sodium salt monohydrate

Dicloxacillin sodium salt monohydrate

CAS No.:
13412-64-1
Catalog Number:
AG008031
Molecular Formula:
C19H18Cl2N3NaO6S
Molecular Weight:
510.3235
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
95-102% (HPLC, Dried basis)
1 week
United States
$67
- +
5g
95-102% (HPLC, Dried basis)
1 week
United States
$140
- +
25g
95-102% (HPLC, Dried basis)
1 week
United States
$462
- +
Product Description
Catalog Number:
AG008031
Chemical Name:
Dicloxacillin sodium salt monohydrate
CAS Number:
13412-64-1
Molecular Formula:
C19H18Cl2N3NaO6S
Molecular Weight:
510.3235
MDL Number:
MFCD00167147
IUPAC Name:
sodium;(2S,5R,6R)-6-[[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;hydrate
InChI:
InChI=1S/C19H17Cl2N3O5S.Na.H2O/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24;;/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28);;1H2/q;+1;/p-1/t13-,14+,17-;;/m1../s1
InChI Key:
SIGZQNJITOWQEF-VICXVTCVSA-M
SMILES:
[O-]C(=O)C1N2C(=O)C(C2SC1(C)C)NC(=O)c1c(C)onc1c1c(Cl)cccc1Cl.O.[Na+]
UNII:
4HZT2V9KX0
Properties
Complexity:
752  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
0
Exact Mass:
509.019g/mol
Formal Charge:
0
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
510.318g/mol
Monoisotopic Mass:
509.019g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
142A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Risk factors for Clostridium difficile toxin-positive diarrhea: a population-based prospective case-control study. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20121001
The alpha-synuclein 5'untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen. Journal of neural transmission (Vienna, Austria : 1996) 20110301
IL-4 mediates dicloxacillin-induced liver injury in mice. Toxicology letters 20110205
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals 20101201
Simultaneous determination of cefixime trihydrate and dicloxacillin sodium in pharmaceutical dosage form by reversed-phase high-performance liquid chromatography. Journal of AOAC International 20100101
Case report: Report of a rare case of juvenile recurrent parotitis and review of literature. European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry 20091101
Pyomyositis in children: early diagnosis and treatment. Journal of pediatric surgery 20091101
[Allergy and skin infection after use of temporary henna tattoo--case report]. Laeknabladid 20091101
Telephone-based management of lactation mastitis. The Journal of reproductive medicine 20090501
[Bacterial pyomyositis in a 12-year-old girl without fever]. Ugeskrift for laeger 20090302
Single time point isothermal drug stability experiments at constant humidity. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090301
Lack of effect of P-glycoprotein inhibition on renal clearance of dicloxacillin in patients with cystic fibrosis. Pharmacotherapy 20080701
Solubilization and stabilization of sodium dicloxacillin by cyclodextrin inclusion. Current drug discovery technologies 20080601
Unusual presentation of ORF in an otherwise healthy individual. Acta dermato-venereologica 20080101
Identification and characterization of degradation products of dicloxacillin in bulk drug and pharmaceutical dosage forms. Journal of pharmaceutical and biomedical analysis 20070312
Spectrophotometric study of the reaction mechanism between DDQ as pi-acceptor and potassium iodate and flucloxacillin and dicloxacillin drugs and their determination in pure and in dosage forms. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060901
Surface and bulk properties of two anionic amphiphilic penicillins in a selective solvent. The journal of physical chemistry. B 20060720
Development of a validated HPLC method for the determination of four penicillin antibiotics in pharmaceuticals and human biological fluids. Journal of separation science 20060701
Spectrophotometric determination of flucloxacillin and dicloxacillin in pure and dosage forms. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Recurrent staphylococcal conjunctivitis associated with facial impetigo contagiosa. American journal of ophthalmology 20060101
Clinical manifestations and outcome in Staphylococcus aureus endocarditis among injection drug users and nonaddicts: a prospective study of 74 patients. BMC infectious diseases 20060101
In vitro activity effects of combinations of cephalothin, dicloxacillin, imipenem, vancomycin and amikacin against methicillin-resistant Staphylococcus spp. strains. Annals of clinical microbiology and antimicrobials 20060101
Thermodynamic study of the effect of ethanol on two amphiphilic penicillins. The journal of physical chemistry. B 20051201
Influence of sub-inhibitory concentrations of antimicrobial agents on biofilm formation in indwelling medical devices. The International journal of artificial organs 20051101
Effect of the MDR1 C3435T variant and P-glycoprotein induction on dicloxacillin pharmacokinetics. Journal of clinical pharmacology 20050401
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery 20050101
[Treatment of chronic bovine endometritis and factors for treatment success]. DTW. Deutsche tierarztliche Wochenschrift 20050101
The relationship between inhibition of bacterial adhesion to a solid surface by sub-MICs of antibiotics and subsequent development of a biofilm. Research in microbiology 20050101
Cheilitis glandularis in an African-American woman: response to antibiotic therapy. Skinmed 20050101
Cases from the aerospace medicine residents' teaching file: furunculosis. Aviation, space, and environmental medicine 20041101
Liquid chromatographic assay for dicloxacillin in plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040615
Interaction of dicloxacillin with warfarin. The Annals of pharmacotherapy 20040501
Dicloxacillin and erythromycin at high concentrations increase ICAM-1 expression by endothelial cells: a possible factor in the pathogenesis of infusion phlebitis. The Journal of antimicrobial chemotherapy 20040201
Large-volume sample stacking combined with separation by 2-hydroxypropyl-beta-cyclodextrin for analysis of isoxyzolylpenicillins by capillary electrophoresis. Electrophoresis 20030901
[Long-term antibiotic suppressive therapy for an infected thoracic aorta graft]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20030828
Antibiotic concentrations in serum and wound fluid after local gentamicin or intravenous dicloxacillin prophylaxis in cardiac surgery. Scandinavian journal of infectious diseases 20030101
Dicloxacillin: a higher risk than cloxacillin for infusion phlebitis. Scandinavian journal of infectious diseases 20030101
Compatibility between active components of a commercial drug. Farmaco (Societa chimica italiana : 1989) 20021001
Eruption on the face. Bulla formation and crusting on the forehead and nose can be easily treated. Geriatrics 20020901
Staphylococcal scalded skin syndrome complicating acute generalized pustular psoriasis. The Australasian journal of dermatology 20020801
In vitro susceptibility of Staphylococcus aureus towards amoxycillin-clavulanic acid, penicillin-clavulanic acid, dicloxacillin and cefuroxime. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20020801
Severe hypokalaemia secondary to dicloxacillin. Internal medicine journal 20020701
Treatment and outcome of Staphylococcus aureus bacteremia: a prospective study of 278 cases. Archives of internal medicine 20020114
Cefuroxime vs a dicloxacillin/chloramphenicol combination for the treatment of parapneumonic pleural effusion and empyema in children. Pulmonary pharmacology & therapeutics 20020101
PKQuest: capillary permeability limitation and plasma protein binding - application to human inulin, dicloxacillin and ceftriaxone pharmacokinetics. BMC clinical pharmacology 20020101
Determination of benzylpenicillin, oxacillin, cloxacillin, and dicloxacillin in cows' milk by ion-pair high-performance liquid chromatography after precolumn derivatization. Fresenius' journal of analytical chemistry 20010901
Metal complexes of antibiotic drugs. Studies on dicluxacillin complexes of FeII, FeIII, CoII NiII and CuII. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20010701
Short-term effects of four antibiotics on DNA synthesis in endothelial cells. Pharmacology & toxicology 20010401
Spectrophotometric determination of ampicillin, dicluxacillin, flucloxacillin and amoxicillin antibiotic drugs: ion-pair formation with molybdenum and thiocyanate. Journal of pharmaceutical and biomedical analysis 20010201
A rare case of osteomyelitis of the sternum in an adult with sickle cell disease. Hemoglobin 20010201
Nephrotoxicity by dicloxacillin and gentamicin in 163 patients with intertrochanteric hip fractures. International orthopaedics 20000701
Prosthetic heart valve thrombosis during dicloxacillin therapy. Scandinavian cardiovascular journal : SCJ 19990101
Possible granulomatous hepatitis after dicloxacillin therapy. Journal of clinical gastroenterology 19960301
Prolonged jaundice after dicloxacillin therapy. The American journal of gastroenterology 19930801
Methicillin-resistant staphylococcal urinary tract infection treated with dicloxacillin. The Journal of the Oklahoma State Medical Association 19930201
Cholestatic hepatitis after dicloxacillin-sodium therapy. Journal of clinical gastroenterology 19860201
Renal impairment after high doses of dicloxacillin-prophylaxis in joint replacement surgery. Acta orthopaedica Scandinavica 19840801
Antibiotic prophylaxis in open and closed fractures: a controlled clinical trial. Acta orthopaedica Scandinavica 19820201
Carbenicillin nephrotoxicity. Southern medical journal 19780101
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