1-Pyrrolidinecarboxaldehyde, 3-(1,3-benzodioxol-5-ylmethylene)-2-oxo-
| Title | Journal |
|---|---|
| Heat Shock Protein 70 Prevents Hyperoxia-Induced Disruption of Lung Endothelial Barrier via Caspase-Dependent and AIF-Dependent Pathways. | PloS one 20150101 |
| Protective HSP70 Induction by Z-Ligustilide against Oxygen-Glucose Deprivation Injury via Activation of the MAPK Pathway but Not of HSF1. | Biological & pharmaceutical bulletin 20150101 |
| Inhibition of inducible heat shock protein-70 (hsp72) enhances bortezomib-induced cell death in human bladder cancer cells. | PloS one 20130101 |
| Heat shock cognate 70 regulates the translocation and angiogenic function of nucleolin. | Arteriosclerosis, thrombosis, and vascular biology 20120901 |
| KNK437, abrogates hypoxia-induced radioresistance by dual targeting of the AKT and HIF-1α survival pathways. | Biochemical and biophysical research communications 20120511 |
| Sodium arsenite and cadmium chloride induction of proteasomal inhibition and HSP accumulation in Xenopus laevis A6 kidney epithelial cells. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120301 |
| Alkannin, HSP70 inducer, protects against UVB-induced apoptosis in human keratinocytes. | PloS one 20120101 |
| Combining curcumin (diferuloylmethane) and heat shock protein inhibition for neurofibromatosis 2 treatment: analysis of response and resistance pathways. | Molecular cancer therapeutics 20111101 |
| KNK437 downregulates heat shock protein 27 of pancreatic cancer cells and enhances the cytotoxic effect of gemcitabine. | Chemotherapy 20110101 |
| KNK437, a benzylidene lactam compound, sensitises prostate cancer cells to the apoptotic effect of hyperthermia. | International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20110101 |
| Human neuroblastoma SH-SY5Y cells show increased resistance to hyperthermic stress after differentiation, associated with elevated levels of Hsp72. | International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20110101 |
| Temperature as a universal resetting cue for mammalian circadian oscillators. | Science (New York, N.Y.) 20101015 |
| Intracellular or extracellular heat shock protein 70 differentially regulates cardiac remodelling in pressure overload mice. | Cardiovascular research 20101001 |
| Targeting heat shock protein 72 enhances Hsp90 inhibitor-induced apoptosis in myeloma. | Leukemia 20101001 |
| Abrogating HSP response augments cell death induced by As2O3 in glioma cell lines. | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20100701 |
| Celastrol can inhibit proteasome activity and upregulate the expression of heat shock protein genes, hsp30 and hsp70, in Xenopus laevis A6 cells. | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20100601 |
| N-Formyl-3,4-methylenedioxy-benzylidene-gamma-butyrolaetam, KNK437 induces caspase-3 activation through inhibition of mTORC1 activity in Cos-1 cells. | Biochemical and biophysical research communications 20100423 |
| Heat shock cognate protein 70 is essential for Akt signaling in endothelial function. | Arteriosclerosis, thrombosis, and vascular biology 20100301 |
| Apoptosis induction in human leukemic cells by a novel protein Bengalin, isolated from Indian black scorpion venom: through mitochondrial pathway and inhibition of heat shock proteins. | Chemico-biological interactions 20100127 |
| Investigation of the eIF2alpha phosphorylation mechanism in response to proteasome inhibition in melanoma and breast cancer cells. | Molekuliarnaia biologiia 20100101 |
| Heat shock protein inhibitors, 17-DMAG and KNK437, enhance arsenic trioxide-induced mitotic apoptosis. | Toxicology and applied pharmacology 20090415 |
| DNA-dependent protein kinase is involved in heat shock protein-mediated accumulation of hypoxia-inducible factor-1alpha in hypoxic preconditioned HepG2 cells. | The FEBS journal 20081201 |
| Comparison of the effect of heat shock factor inhibitor, KNK437, on heat shock- and chemical stress-induced hsp30 gene expression in Xenopus laevis A6 cells. | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20081001 |
| Heat shock protein 70 of Naegleria fowleri is important factor for proliferation and in vitro cytotoxicity. | Parasitology research 20080701 |
| Development of thermotolerance requires interaction between polymerase-beta and heat shock proteins. | Cancer science 20080501 |
| HSPA1A is an important regulator of the stability and function of ZNF198 and its oncogenic derivative, ZNF198-FGFR1. | Journal of cellular biochemistry 20071201 |
| Examination of KNK437- and quercetin-mediated inhibition of heat shock-induced heat shock protein gene expression in Xenopus laevis cultured cells. | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20071101 |
| The heat shock protein inhibitor KNK437 induces neurite outgrowth in PC12 cells. | Neuroscience letters 20061227 |
| Effects of KNK437 on heat-induced methylation of histone H3 in human oral squamous cell carcinoma cells. | International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20061201 |
| Oral pretreatment with ebselen enhances heat shock protein 72 expression and reduces myocardial infarct size. | Hypertension research : official journal of the Japanese Society of Hypertension 20061101 |
| Induction of radiation resistance by a heat shock protein inhibitor, KNK437, in human glioblastoma cells. | International journal of radiation biology 20060801 |
| Valproic acid-mediated Hsp70 induction and anti-apoptotic neuroprotection in SH-SY5Y cells. | FEBS letters 20051219 |
| Abrogation of heat shock protein 70 induction as a strategy to increase antileukemia activity of heat shock protein 90 inhibitor 17-allylamino-demethoxy geldanamycin. | Cancer research 20051115 |
| Attenuation of chronic thermotolerance by KNK437, a benzylidene lactam compound, enhances thermal radiosensitization in mild temperature hyperthermia combined with low dose-rate irradiation. | International journal of radiation biology 20050901 |
| Effects of a heat shock protein inhibitor KNK437 on heat sensitivity and heat tolerance in human squamous cell carcinoma cell lines differing in p53 status. | International journal of radiation biology 20040801 |
| Changes in the number of HSF1 positive granules in the nucleus reflects heat shock semiquantitatively. | Cancer letters 20031208 |
| Changes in the localization of heat shock protein 72 correlated with development of thermotolerance in human esophageal cancer cell line. | Anticancer research 20030101 |
| The effects of KNK437, a novel inhibitor of heat shock protein synthesis, on the acquisition of thermotolerance in a murine transplantable tumor in vivo. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010101 |