Name: Name:2,5-Pyrrolidinedione,1-(3,5-dichlorophenyl)-
Brand: Angene
SKU: AG007O8I
Rating: 90 (10 reviews)

Catalog Number:

AG007O8I

Chemical Name:

2,5-Pyrrolidinedione,1-(3,5-dichlorophenyl)-

CAS Number:

24096-53-5

Molecular Formula:

C10H7Cl2NO2

Molecular Weight:

244.0741

MDL Number:

MFCD00176441

IUPAC Name:

1-(3,5-dichlorophenyl)pyrrolidine-2,5-dione

InChI:

InChI=1S/C10H7Cl2NO2/c11-6-3-7(12)5-8(4-6)13-9(14)1-2-10(13)15/h3-5H,1-2H2

InChI Key:

CFZLNRGUBAVQNO-UHFFFAOYSA-N

SMILES:

O=C1CCC(=O)N1c1cc(Cl)cc(c1)Cl

Complexity:

269

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

1

Defined Atom Stereocenter Count:

0

Defined Bond Stereocenter Count:

0

Exact Mass:

242.985g/mol

Formal Charge:

0

Heavy Atom Count:

15

Hydrogen Bond Acceptor Count:

2

Hydrogen Bond Donor Count:

0

Isotope Atom Count:

0

Molecular Weight:

244.071g/mol

Monoisotopic Mass:

242.985g/mol

Rotatable Bond Count:

1

Topological Polar Surface Area:

37.4A^2

Undefined Atom Stereocenter Count:

0

Undefined Bond Stereocenter Count:

0

XLogP3:

1.6

Title	Journal
Role of leukotrienes in N-(3,5-dichlorophenyl)succinimide (NDPS) and NDPS metabolite nephrotoxicity in male Fischer 344 rats.	Toxicology 20121009
A predictive ligand-based Bayesian model for human drug-induced liver injury.	Drug metabolism and disposition: the biological fate of chemicals 20101201
Synthesis, antifungal activities and 3D-QSAR study of N-(5-substituted-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamides.	European journal of medicinal chemistry 20090701
Nephrotoxicity induced by N-(3,5-dichlorophenyl)-3-hydroxysuccinamic acid in male and female Fischer 344 rats.	Journal of applied toxicology : JAT 20081001
The antiandrogenic activity of the fungicide N-(3, 5-dichlorophenyl) succinimide in in vivo and in vitro assays.	The Journal of reproduction and development 20070601
Transamination in the metabolism of the nephrotoxicant N-(3,5-dichlorophenyl)succinimide in rats.	Drug metabolism and disposition: the biological fate of chemicals 20051201
[The antiandrogenic effect of dimethachlon and its mechanism].	Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20040201
Nephrotoxic and hepatotoxic potential of imidazolidinedione-, oxazolidinedione- and thiazolidinedione-containing analogues of N-(3,5-dichlorophenyl)succinimide (NDPS) in Fischer 344 rats.	Toxicology 20030415
Renal damage, metabolism and covalent binding following administration of the nephrotoxicant N-(3,5-dichlorophenyl)succinimide (NDPS) to male Fischer 344 rats.	Toxicology 20020125
Gender differences in the potentiation of N-(3,5-dichlorophenyl)succinimide metabolite nephrotoxicity by phenobarbital.	Journal of toxicology and environmental health. Part A 20011012
In vitro nephrotoxicity induced by N-(3,5-dichlorophenyl)succinimide (NDPS) metabolites in isolated renal cortical cells from male and female Fischer 344 rats: evidence for a nephrotoxic sulfate conjugate metabolite.	Toxicology 20010621