Home Halogens 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazole; nitric acid

1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazole; nitric acid

CAS No.:
24168-96-5
Catalog Number:
AG007O49
Molecular Formula:
C18H15Cl4N3O4
Molecular Weight:
479.1414
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$13
- +
5g
98%
In Stock USA
United States
$25
- +
25g
98%
In Stock USA
United States
$63
- +
100g
98%
In Stock USA
United States
$150
- +
Product Description
Catalog Number:
AG007O49
Chemical Name:
1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazole; nitric acid
CAS Number:
24168-96-5
Molecular Formula:
C18H15Cl4N3O4
Molecular Weight:
479.1414
MDL Number:
MFCD01721647
IUPAC Name:
1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]imidazole;nitric acid
InChI:
InChI=1S/C18H14Cl4N2O.HNO3/c19-12-4-5-13(17(22)8-12)18(9-24-7-6-23-11-24)25-10-14-15(20)2-1-3-16(14)21;2-1(3)4/h1-8,11,18H,9-10H2;(H,2,3,4)
InChI Key:
NNGQLSIGRSTLLU-UHFFFAOYSA-N
SMILES:
Clc1ccc(c(c1)Cl)C(Cn1cncc1)OCc1c(Cl)cccc1Cl.[O-][N+](=O)O
EC Number:
246-051-4
Properties
Complexity:
431  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
478.979g/mol
Formal Charge:
0
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
479.135g/mol
Monoisotopic Mass:
476.982g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
93.1A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
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Non-invasive analysis of penetration and storage of Isoconazole nitrate in the stratum corneum and the hair follicles. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120401
Liquid chromatographic and spectrophotometric determination of diflucortolone valerate and isoconazole nitrate in creams. Journal of AOAC International 20110101
Otomycosis: Diagnosis and treatment. Clinics in dermatology 20100304
Superficial dermatomycoses worldwide: multinational treatment experience with a combination of isoconazole nitrate and diflucortolone valerate. Introduction. Mycoses 20080901
The advantages of topical combination therapy in the treatment of inflammatory dermatomycoses. Mycoses 20080901
Successful therapy of tinea cruris with topical isoconazole in combination with a corticosteroid. Mycoses 20080901
The effective use of isoconazole nitrate and diflucortolone valerate cream in the treatment of inguino-femoral skin fold mycosis. Mycoses 20080901
Tinea cruris treated with a combined topical therapy containing isoconazole and a corticosteroid. Mycoses 20080901
Tinea corporis of the shin and chest successfully treated with a topical antifungal and corticosteroid cream. Mycoses 20080901
Tinea corporis treated with a combined topical therapy containing isoconazole and a corticosteroid. Mycoses 20080901
Tinea incognito due to Trichophyton rubrum responsive to topical therapy with isoconazole plus corticosteroid cream. Mycoses 20080901
Treatment of candidal intertrigo with a topical combination of isoconazole nitrate and diflucortolone valerate. Mycoses 20080901
Topical treatment of intertriginous candidal infection. Mycoses 20080901
Balanitis with eczematous perigenital intertriginous candidosis. Mycoses 20080901
Successful treatment of tinea pedis with a topical agent containing isoconazole nitrate and diflucortolone valerate. Mycoses 20080901
Step-wise treatment of athlete's foot (tinea pedis) using isoconazole combined with a corticosteroid followed by isoconazole alone. Mycoses 20080901
Dermatoscopy in the diagnosis of tinea nigra. Dermatology online journal 20080815
Line-walking method for predicting the inhibition of P450 drug metabolism. Journal of medicinal chemistry 20060713
Susceptibility to some antifungal drugs of vaginal lactobacilli isolated from healthy women. Drug metabolism and drug interactions 20050101
In vitro antifungal activity of sertaconazole compared with nine other drugs against 250 clinical isolates of dermatophytes and Scopulariopsis brevicaulis. Chemotherapy 20041201
[The problem of otomycosis treatment]. Voenno-meditsinskii zhurnal 20030201
Pityriasis versicolor rubra. European journal of dermatology : EJD 20020101
[Vaginal candidiasis: etiology and sensitivity profile to antifungal agents in clinical use]. Revista Argentina de microbiologia 20010101
[The in vitro properties of a new hydroxypyridone antimycotic rilopirox, with special reference to its anti-Candida activity]. The Japanese journal of antibiotics 19990201
In vitro activity of cloconazole, sulconazole, butoconazole, isoconazole, fenticonazole, and five other antifungal agents against clinical isolates of Candida albicans and Candida spp. Mycopathologia 19920401
Isoconazole nitrate versus clotrimazole in foot and nail infections due to Hendersonula toruloidea, Scytalidium hyalinum and dermatophytes. Mycoses 19920101
Properties