Thieno[3,2-d]pyrimidine
| Title | Journal |
|---|---|
| Synthesis and biological evaluation of triazolothienopyrimidine derivatives as novel HIV-1 replication inhibitors. | Bioorganic & medicinal chemistry letters 20130101 |
| Synthesis and evaluation of apoptosis induction of thienopyrimidine compounds on KRAS and BRAF mutated colorectal cancer cell lines. | Bioorganic & medicinal chemistry 20121115 |
| Design, synthesis and biological evaluation of some novel thienopyrimidines and fused thienopyrimidines as anti-inflammatory agents. | European journal of medicinal chemistry 20120901 |
| Thieno analogues of RNA nucleosides: a detailed theoretical study. | The journal of physical chemistry. B 20120705 |
| Synthesis and antimicrobial activity of new substituted thienopyrimidines, their tetrazolyl and sugar derivatives. | Acta poloniae pharmaceutica 20120101 |
| Synthesis and anti-tumor activities of N'-benzylidene-2-(4-oxothieno[2,3-d]pyrimidin-3(4H)-yl)acetohydrazone derivatives. | Bioorganic & medicinal chemistry letters 20111115 |
| Thienopyrimidines as novel inhibitors of Mycobacterium tuberculosis: synthesis and in-vitro studies. | Archiv der Pharmazie 20110701 |
| Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2. | European journal of medicinal chemistry 20110301 |
| The highly potent and selective dipeptidyl peptidase IV inhibitors bearing a thienopyrimidine scaffold effectively treat type 2 diabetes. | European journal of medicinal chemistry 20110101 |
| Synthesis, antitrichinnellosis and antiprotozoal activity of some novel thieno[2,3-d]pyrimidin-4(3H)-ones containing benzimidazole ring. | European journal of medicinal chemistry 20101201 |
| Synthesis and screening of some novel fused thiophene and thienopyrimidine derivatives for anti-avian influenza virus (H5N1) activity. | European journal of medicinal chemistry 20101101 |
| Design and synthesis of novel thiophenecarbohydrazide, thienopyrazole and thienopyrimidine derivatives as antioxidant and antitumor agents. | Acta pharmaceutica (Zagreb, Croatia) 20100901 |
| Novel thiophenes, thienopyrimidines, and triazolothienopyrimidines for the evaluation of anticancer and augmentation effects of gamma-radiation. | Archiv der Pharmazie 20100701 |
| Recent advances in the development of selective, ATP-competitive inhibitors of mTOR. | Current opinion in drug discovery & development 20100701 |
| Synthesis and study of antiproliferative activity of novel thienopyrimidines on glioblastoma cells. | European journal of medicinal chemistry 20100601 |
| Synthesis and theoretical studies on energetics of novel N- and O- perfluoroalkyl triazole tagged thienopyrimidines--their potential as adenosine receptor ligands. | European journal of medicinal chemistry 20100501 |
| Thieno[2,3-d]pyrimidines in the synthesis of antitumor and antioxidant agents. | Archiv der Pharmazie 20100501 |
| Discovery of 3,6-dihydro-2H-pyran as a morpholine replacement in 6-aryl-1H-pyrazolo[3,4-d]pyrimidines and 2-arylthieno[3,2-d]pyrimidines: ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR). | Bioorganic & medicinal chemistry letters 20100115 |
| Discovery of 2-arylthieno[3,2-d]pyrimidines containing 8-oxa-3-azabi-cyclo[3.2.1]octane in the 4-position as potent inhibitors of mTOR with selectivity over PI3K. | Bioorganic & medicinal chemistry letters 20100101 |
| Direct metallation of thienopyrimidines using a mixed lithium-cadmium base and antitumor activity of functionalized derivatives. | Organic & biomolecular chemistry 20091121 |
| Analogs of a 4-aminothieno[2,3-d]pyrimidine lead (QB13) as modulators of P-glycoprotein substrate specificity. | Bioorganic & medicinal chemistry letters 20091101 |
| Discovery and optimization of potent and selective functional antagonists of the human adenosine A2B receptor. | Bioorganic & medicinal chemistry letters 20091015 |
| Tricyclic thienopyridine-pyrimidones/thienopyrimidine-pyrimidones as orally efficacious mGluR1 antagonists for neuropathic pain. | Bioorganic & medicinal chemistry letters 20090615 |
| Enzymatic incorporation of emissive pyrimidine ribonucleotides. | Chemistry, an Asian journal 20090302 |
| Synthesis and evaluation of aniline headgroups for alkynyl thienopyrimidine dual EGFR/ErbB-2 kinase inhibitors. | Bioorganic & medicinal chemistry letters 20090301 |
| Thienopyrimidine-based dual EGFR/ErbB-2 inhibitors. | Bioorganic & medicinal chemistry letters 20090201 |
| Increased plasma membrane expression of human follicle-stimulating hormone receptor by a small molecule thienopyr(im)idine. | Molecular and cellular endocrinology 20090127 |
| The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer . | Journal of medicinal chemistry 20080925 |
| Synthesis and adenosine receptor binding studies of some novel triazolothienopyrimidines. | European journal of medicinal chemistry 20080301 |
| Synthesis and antimicrobial evaluation of some new thienopyrimidine derivatives. | Acta pharmaceutica (Zagreb, Croatia) 20061201 |
| Synthesis and biological evaluation of 4-morpholino-2-phenylquinazolines and related derivatives as novel PI3 kinase p110alpha inhibitors. | Bioorganic & medicinal chemistry 20061015 |
| A low molecular weight agonist signals by binding to the transmembrane domain of thyroid-stimulating hormone receptor (TSHR) and luteinizing hormone/chorionic gonadotropin receptor (LHCGR). | The Journal of biological chemistry 20060414 |
| Synthesis and antiviral screening of some thieno[2,3-d]pyrimidine nucleosides. | Nucleosides, nucleotides & nucleic acids 20060101 |
| Thienopyrimidine ureas as novel and potent multitargeted receptor tyrosine kinase inhibitors. | Journal of medicinal chemistry 20050922 |
| Synthesis of new iso-C-nucleoside analogues from 2-(methyl 2-O-benzyl-4,6-O-benzylidene-3-deoxy-alpha-D-altropyranosid-3-yl)ethanal. | Carbohydrate research 20050321 |
| Long-term benefits of an early invasive management in acute coronary syndromes depend on intracoronary stenting and aggressive antiplatelet treatment: a metaregression. | American heart journal 20050301 |
| Endothelial action of thienopyridines and thienopyrimidinones in the isolated guinea pig heart. | Prostaglandins, leukotrienes, and essential fatty acids 20050201 |
| Synthesis of novel acyclonucleosides analogs of pyridothienopyrimidine as antiviral agents. | Nucleosides, nucleotides & nucleic acids 20050101 |
| Synthesis and antimicrobial activity of novel tetrahydrobenzothienopyrimidines. | Archives of pharmacal research 20040901 |
| Focusing on inflammation in the treatment of atherosclerosis. | Cardiology in review 20040101 |
| Synthesis of substituted thienopyrimidine-4-ones. | Journal of combinatorial chemistry 20040101 |
| Synthesis and preliminary evaluation of some N-[5-(2-furanyl)-2-methyl-4-oxo-4H-thieno[2,3-d]pyrimidin-3-yl]-carboxamide and 3-substituted-5-(2-furanyl)-2-methyl-3H-thieno[2,3-d]pyrimidin-4-ones as antimicrobial agents. | European journal of medicinal chemistry 20030101 |