Home Aminos (2R)-2-amino-4-methylpentanoic acid

(2R)-2-amino-4-methylpentanoic acid

CAS No.:
328-38-1
Catalog Number:
AG007IPP
Molecular Formula:
C6H13NO2
Molecular Weight:
131.1729
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
98%
In Stock USA
United States
$13
- +
25g
98%
In Stock USA
United States
$35
- +
100g
98%
In Stock USA
United States
$107
- +
500g
98%
In Stock USA
United States
$375
- +
Product Description
Catalog Number:
AG007IPP
Chemical Name:
(2R)-2-amino-4-methylpentanoic acid
CAS Number:
328-38-1
Molecular Formula:
C6H13NO2
Molecular Weight:
131.1729
MDL Number:
MFCD00063088
IUPAC Name:
(2R)-2-amino-4-methylpentanoic acid
InChI:
InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m1/s1
InChI Key:
ROHFNLRQFUQHCH-RXMQYKEDSA-N
SMILES:
N[C@@H](C(=O)O)CC(C)C
EC Number:
206-327-7
UNII:
965COD96YA
Properties
Complexity:
101  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
131.095g/mol
Formal Charge:
0
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
131.175g/mol
Monoisotopic Mass:
131.095g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
63.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.5  
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Volatile profiling reveals intracellular metabolic changes in Aspergillus parasiticus: veA regulates branched chain amino acid and ethanol metabolism. BMC biochemistry 20100101
Oral microencapsulated live Saccharomyces cerevisiae cells for use in renal failure uremia: preparation and in vivo analysis. Journal of biomedicine & biotechnology 20100101
Proteome-wide search reveals unexpected RNA-binding proteins in Saccharomyces cerevisiae. PloS one 20100101
TLRs in Hepatic Cellular Crosstalk. Gastroenterology research and practice 20100101
Iodothyronine Interactions with the System L1 Amino Acid Exchanger in 3T3-L1 Adipocytes. Journal of thyroid research 20100101
Impaired growth and force production in skeletal muscles of young partially pancreatectomized rats: a model of adolescent type 1 diabetic myopathy? PloS one 20100101
Metabolomic profiling of cellular responses to carvedilol enantiomers in vascular smooth muscle cells. PloS one 20100101
Cationic amino acid transporters and Salmonella Typhimurium ArgT collectively regulate arginine availability towards intracellular Salmonella growth. PloS one 20100101
Identification and Partial Characterization of an L-Tyrosine Aminotransferase (TAT) from Arabidopsis thaliana. Biochemistry research international 20100101
Peyer's Patches: The Immune Sensors of the Intestine. International journal of inflammation 20100101
Leaf-cutting ant fungi produce cell wall degrading pectinase complexes reminiscent of phytopathogenic fungi. BMC biology 20100101
The effect of oral leucine on protein metabolism in adolescents with type 1 diabetes mellitus. International journal of pediatric endocrinology 20100101
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Preparation of antioxidant enzymatic hydrolysates from honeybee-collected pollen using plant enzymes. Enzyme research 20100101
Translational selection on SHH genes. Genetics and molecular biology 20100101
Intelligent chiral sensing based on supramolecular and interfacial concepts. Sensors (Basel, Switzerland) 20100101
Studies of enthalpy-entropy compensation, partial entropies, and Kirkwood-Buff integrals for aqueous solutions of glycine, L-leucine, and glycylglycine at 298.15 K. The journal of physical chemistry. B 20091231
A post-modification approach to peptide foldamers. Organic & biomolecular chemistry 20091221
Simultaneously manufactured nano-in-micro (SIMANIM) particles for dry-powder modified-release delivery of antibodies. Journal of pharmaceutical sciences 20091101
The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system. Endocrinology 20091101
Statistical optimization for improved production of cyclosporin a in solid-state fermentation. Journal of microbiology and biotechnology 20091101
Standard-free quantitation of mixtures using clusters formed by electrospray mass spectrometry. Analytical chemistry 20091015
Sodium and potassium ion directed self-assembled multinuclear assembly of divalent nickel or copper and L-leucine derived ligand. Inorganic chemistry 20091005
Luminal L-glutamate enhances duodenal mucosal defense mechanisms via multiple glutamate receptors in rats. American journal of physiology. Gastrointestinal and liver physiology 20091001
Expression and mechanism of mammalian target of rapamycin in age-related renal cell senescence and organ aging. Mechanisms of ageing and development 20091001
New Ras CAAX mimetics: design, synthesis, antiproliferative activity, and RAS prenylation inhibition. Bioorganic & medicinal chemistry letters 20090915
Effect of L-leucine graft content on aqueous solution behavior and membrane-lytic activity of a pH-responsive pseudopeptide. Biomacromolecules 20090914
Retraction note on: The influence of sodium hyaluronate, l-leucine and sodium taurocholate on the nebulization of aqueous betamethasone-17-valerate suspensions. AAPS PharmSciTech 20090901
Role of protease inhibitors and acylation stimulating protein in the adipogenesis in 3T3-L1 cells. Journal of veterinary science 20090901
REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasis. PLoS biology 20090901
Static solid-state (14)N NMR and computational studies of nitrogen EFG tensors in some crystalline amino acids. Physical chemistry chemical physics : PCCP 20090828
Mapping of the allosteric network in the regulation of alpha-isopropylmalate synthase from Mycobacterium tuberculosis by the feedback inhibitor L-leucine: solution-phase H/D exchange monitored by FT-ICR mass spectrometry. Biochemistry 20090811
Gastric mammalian target of rapamycin signaling regulates ghrelin production and food intake. Endocrinology 20090801
Oral administration of Excitin-1 (beta-alanyl-L-leucine) alters behavior and brain monoamine and amino acid concentrations in rats. Nutritional neuroscience 20090801
Glutamine inhibits ammonia-induced accumulation of cGMP in rat striatum limiting arginine supply for NO synthesis. Neurobiology of disease 20090701
Combination chemotherapeutic dry powder aerosols via controlled nanoparticle agglomeration. Pharmaceutical research 20090701
Kokumi-active glutamyl peptides in cheeses and their biogeneration by Penicillium roquefortii. Journal of agricultural and food chemistry 20090513
Biosynthesis of the cyclooligomer depsipeptide bassianolide, an insecticidal virulence factor of Beauveria bassiana. Fungal genetics and biology : FG & B 20090501
Taurine supplementation enhances nutrient-induced insulin secretion in pancreatic mice islets. Diabetes/metabolism research and reviews 20090501
Tuning the activation threshold of a kinase network by nested feedback loops. Science (New York, N.Y.) 20090424
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The role of hydrophobic amino acid grafts in the enhancement of membrane-disruptive activity of pH-responsive pseudo-peptides. Biomaterials 20090401
Effect of amino acids on tannase biosynthesis by Bacillus licheniformis KBR6. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20090401
Kinetic evidence for interdomain communication in the allosteric regulation of alpha-isopropylmalate synthase from Mycobacterium tuberculosis. Biochemistry 20090310
Antigenic, microbicidal and antiparasitic properties of an l-amino acid oxidase isolated from Bothrops jararaca snake venom. Toxicon : official journal of the International Society on Toxinology 20090301
Ten novel HMGCL mutations in 24 patients of different origin with 3-hydroxy-3-methyl-glutaric aciduria. Human mutation 20090301
The identification of nonpeptide neurotensin receptor partial agonists from the potent antagonist SR48692 using a calcium mobilization assay. Bioorganic & medicinal chemistry letters 20090301
Metabolic engineering of the L-valine biosynthesis pathway in Corynebacterium glutamicum using promoter activity modulation. Journal of biotechnology 20090205
Universal and species-specific bacterial 'fungiphiles' in the mycospheres of different basidiomycetous fungi. Environmental microbiology 20090201
Biodegradable polydepsipeptides. International journal of molecular sciences 20090201
Cycloheximide treatment induces the uptake of neutral and dibasic amino acids via the activation of system b(0,+) in human intestinal Caco-2 cells. Journal of nutritional science and vitaminology 20090201
Solid-state NMR studies of aminocarboxylic salt bridges in L-lysine modified cellulose. The journal of physical chemistry. B 20090129
Effects of disintegration-promoting agent, lubricants and moisture treatment on optimized fast disintegrating tablets. International journal of pharmaceutics 20090105
Aerosolization behavior of carrier-free L-leucine coated salbutamol sulphate powders. International journal of pharmaceutics 20090105
Molecularly designed surfaces for blood deheparinization using an immobilized heparin-binding peptide. Journal of biomedical materials research. Part A 20090101
Zyxin is a novel interacting partner for SIRT1. BMC cell biology 20090101
Metabolic profiling of the response to an oral glucose tolerance test detects subtle metabolic changes. PloS one 20090101
The effect of high glucocorticoid administration and food restriction on rodent skeletal muscle mitochondrial function and protein metabolism. PloS one 20090101
Aerosol performance of large respirable particles of amikacin sulfate produced by spray and freeze drying techniques. Current drug delivery 20090101
Testis-expressed profilins 3 and 4 show distinct functional characteristics and localize in the acroplaxome-manchette complex in spermatids. BMC cell biology 20090101
Exploring functional beta-cell heterogeneity in vivo using PSA-NCAM as a specific marker. PloS one 20090101
PimT, an amino acid exporter controls polyene production via secretion of the quorum sensing pimaricin-inducer PI-factor in Streptomyces natalensis. Microbial cell factories 20090101
Characterization of alpha-isopropylmalate synthases containing different copy numbers of tandem repeats in Mycobacterium tuberculosis. BMC microbiology 20090101
Poly(ester amide) co-polymers promote blood and tissue compatibility. Journal of biomaterials science. Polymer edition 20090101
Bacillus cereus spores release alanine that synergizes with inosine to promote germination. PloS one 20090101
Potentials and limitations of microorganisms as renal failure biotherapeutics. Biologics : targets & therapy 20090101
The formin-homology protein SmDia interacts with the Src kinase SmTK and the GTPase SmRho1 in the gonads of Schistosoma mansoni. PloS one 20090101
Protein hydrolysates in sports nutrition. Nutrition & metabolism 20090101
Conformational changes and loose packing promote E. coli Tryptophanase cold lability. BMC structural biology 20090101
Dual localized AtHscB involved in iron sulfur protein biogenesis in Arabidopsis. PloS one 20090101
Mechanisms of amino acid sensing in mTOR signaling pathway. Nutrition research and practice 20090101
A taxonomy of epithelial human cancer and their metastases. BMC medical genomics 20090101
MEF2C silencing attenuates load-induced left ventricular hypertrophy by modulating mTOR/S6K pathway in mice. PloS one 20090101
Performance of the auxotrophic Saccharomyces cerevisiae BY4741 as host for the production of IL-1beta in aerated fed-batch reactor: role of ACA supplementation, strain viability, and maintenance energy. Microbial cell factories 20090101
Heating improves poor compliance with branched chain amino acid-rich supplementation in patients with liver cirrhosis: A before-after pilot study. Molecular medicine reports 20090101
Escherichia coli, an Intestinal Microorganism, as a Biosensor for Quantification of Amino Acid Bioavailability. Sensors (Basel, Switzerland) 20090101
L-leucine increases [3H]-thymidine incorporation in chicken hepatocytes: involvement of the PKC, PI3K/Akt, ERK1/2, and mTOR signaling pathways. Journal of cellular biochemistry 20081215
Novel mechanistic aspects on the reaction between low spin Fe(II) Schiff base amino acid complexes and hydrogen peroxide-spectrophotometric tracer of intraperoxo intermediate catalyzed reaction. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081201
Solvent-free crystallizations of amino acids: the effects of the hydrophilicity/hydrophobicity of side-chains. Biophysical chemistry 20081201
Spontaneous reaction silencing in metabolic optimization. PLoS computational biology 20081201
Peripheral amino Acid levels in schizophrenia and antipsychotic treatment. Psychiatry investigation 20081201
Synthesis, characterization and pharmacological evaluation of amide prodrugs of ketorolac. European journal of medicinal chemistry 20081101
Cospray-dried unfractionated heparin with L-leucine as a dry powder inhaler mucolytic for cystic fibrosis therapy. Journal of pharmaceutical sciences 20081101
The effects of age on uptake, serum half-life and bioavailability of mouse [D-Leu-4]OB3, a synthetic peptide amide with leptin-like activity, in male C57BL/6J mice. Regulatory peptides 20081009
Synthesis, structure, and spectroscopic properties of chiral oxorhenium(V) complexes incorporating polydentate ligands derived from L-amino acids: a density functional theory/time-dependent density functional theory investigation. Inorganic chemistry 20081006
Investigations on the humidity-induced transformations of salbutamol sulphate particles coated with L-leucine. Pharmaceutical research 20081001
Water-soluble gambogic acid PEGylated prodrugs: synthesis, characterization, physicochemical properties and in vitro hydrolysis. Die Pharmazie 20081001
Optimization of 12 chiral analytes with 8 polymeric surfactants. Journal of chromatographic science 20081001
Glutamine-induced membrane currents in cultured rat hippocampal neurons. The European journal of neuroscience 20080801
Inference of protein complex activities from chemical-genetic profile and its applications: predicting drug-target pathways. PLoS computational biology 20080801
Protein properties of mackerel viscera extracted by supercritical carbon dioxide. Journal of environmental biology 20080701
Simultaneous synthesis and coating of salbutamol sulphate nanoparticles with L-leucine in the gas phase. International journal of pharmaceutics 20080624
Physico-chemical investigation of asymmetrical peptidolipidyl-cyclodextrins. Journal of colloid and interface science 20080601
BCH, an inhibitor of system L amino acid transporters, induces apoptosis in cancer cells. Biological & pharmaceutical bulletin 20080601
Overall kinetic mechanism of saccharopine dehydrogenase (L-glutamate forming) from Saccharomyces cerevisiae. Biochemistry 20080513
Pharmaceutical particle engineering via spray drying. Pharmaceutical research 20080501
Conformational flexibility of a model protein upon immobilization on self-assembled monolayers. Biotechnology and bioengineering 20080501
Diversification of an ancient theme: hydroxynitrile glucosides. Phytochemistry 20080501
WITHDRAWN: Amino acids for amyotrophic lateral sclerosis / motor neuron disease. The Cochrane database of systematic reviews 20080416
Characterization and astrocytic modulation of system L transporters in brain microvasculature endothelial cells. Cell biochemistry and function 20080401
L-Amino acid oxidase from Naja naja oxiana venom. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20080401
[Immunoresonance scattering spectral assay of complement factor 4(C4)]. Guang pu xue yu guang pu fen xi = Guang pu 20080401
An allylic ketyl radical intermediate in clostridial amino-acid fermentation. Nature 20080313
Development of spray dried liposomal dry powder inhaler of Dapsone. AAPS PharmSciTech 20080301
The influence of sodium hyaluronate, L-leucine and sodium taurocholate on the nebulization of aqueous betamethasone-17-valerate suspensions. AAPS PharmSciTech 20080301
Production of L-leucine aminopeptidase by selected Streptomyces isolates. Journal of applied microbiology 20080201
Biological and physiological characteristics of Neotyphodium gansuense symbiotic with Achnatherum inebrians. Microbiological research 20080101
A novel gas phase method for the combined synthesis and coating of pharmaceutical particles. Pharmaceutical research 20080101
In vitro modulation of alkaline phosphatase activity of Saccharomyces cerevisiae grown in low or high phosphate medium. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20080101
Differences in muscle protein synthesis and anabolic signaling in the postabsorptive state and in response to food in 65-80 year old men and women. PloS one 20080101
Optimized two-dimensional thin layer chromatography to monitor the intracellular concentration of acetyl phosphate and other small phosphorylated molecules. Biological procedures online 20080101
Comparative transcriptome analysis of Arabidopsis thaliana infested by diamond back moth (Plutella xylostella) larvae reveals signatures of stress response, secondary metabolism, and signalling. BMC genomics 20080101
Limited functional conservation of a global regulator among related bacterial genera: Lrp in Escherichia, Proteus and Vibrio. BMC microbiology 20080101
Microphthalmia and cataract in rats with a novel point mutation in connexin 50 - L7Q. Molecular vision 20080101
The hidden universal distribution of amino acid biosynthetic networks: a genomic perspective on their origins and evolution. Genome biology 20080101
Molecular evolution of B6 enzymes: binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme. BMC biochemistry 20080101
Direct infection and replication of naturally occurring hepatitis C virus genotypes 1, 2, 3 and 4 in normal human hepatocyte cultures. PloS one 20080101
MSDmotif: exploring protein sites and motifs. BMC bioinformatics 20080101
Potential antiproteolytic effects of L-leucine: observations of in vitro and in vivo studies. Nutrition & metabolism 20080101
Overexpression of the riboflavin biosynthetic pathway in Pichia pastoris. Microbial cell factories 20080101
Pancreatic beta-cell purification by altering FAD and NAD(P)H metabolism. Experimental diabetes research 20080101
Novel insights into the unfolded protein response using Pichia pastoris specific DNA microarrays. BMC genomics 20080101
A genome-scale metabolic reconstruction of Pseudomonas putida KT2440: iJN746 as a cell factory. BMC systems biology 20080101
P-loop mutations and novel therapeutic approaches for imatinib failures in chronic myeloid leukemia. Journal of hematology & oncology 20080101
Size-specific, colorimetric detection of counteranions by using helical poly(phenylacetylene) conjugated to L-leucine groups through urea acceptors. Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1. PloS one 20080101
Tripeptide tyroserleutide plus doxorubicin: therapeutic synergy and side effect attenuation. BMC cancer 20080101
MFS transportome of the human pathogenic yeast Candida albicans. BMC genomics 20080101
Dose- and Glucose-Dependent Effects of Amino Acids on Insulin Secretion from Isolated Mouse Islets and Clonal INS-1E Beta-Cells. The review of diabetic studies : RDS 20080101
13C-alpha-Ketoisocaproic acid breath test revisited: an in-depth reproducibility study advocates an extended breath sampling period. Digestive diseases and sciences 20071201
Inhibitory effects of endogenous L-arginine analogues on nitric oxide synthesis in platelets: role in platelet hyperaggregability in hypertension. Clinical and experimental pharmacology & physiology 20071201
Genetic interaction between the ero1-1 and leu2 mutations in Saccharomyces cerevisiae. Bioscience, biotechnology, and biochemistry 20071201
Nano-liposomal dry powder inhaler of tacrolimus: preparation, characterization, and pulmonary pharmacokinetics. International journal of nanomedicine 20071201
Inhibitory properties of nerve-specific human glutamate dehydrogenase isozyme by chloroquine. Journal of biochemistry and molecular biology 20071130
Properties and molecular evolution of human GLUD2 (neural and testicular tissue-specific) glutamate dehydrogenase. Journal of neuroscience research 20071115
Development and validation of a liquid chromatographic method for the determination of branched-chain amino acids in new dosage forms. Journal of pharmaceutical and biomedical analysis 20071105
Molecular genetics of HMG-CoA lyase deficiency. Molecular genetics and metabolism 20071101
Involvement of an enterocyte renin-angiotensin system in the local control of SGLT1-dependent glucose uptake across the rat small intestinal brush border membrane. The Journal of physiology 20071015
Amino acids partitioning in aqueous two-phase system of polypropylene glycol and magnesium sulfate. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071015
Design of organocatalysts for asymmetric direct syn-aldol reactions. Organic letters 20071011
Role of S-nitrosothiol transport in the cardioprotective effects of S-nitrosocysteine in rat hearts. Free radical biology & medicine 20071001
Metabolic and digestive response to food ingestion in a binge-feeding lizard, the Gila monster (Heloderma suspectum). The Journal of experimental biology 20071001
Enantioselective separation of all-E-astaxanthin and its determination in microbial sources. Journal of chromatography. A 20070928
Suppression of myofibrillar proteolysis in chick skeletal muscles by alpha-ketoisocaproate. Amino acids 20070901
Purification of branched-chain amino acid aminotransferase from Helicobacter pylori NCTC 11637. Amino acids 20070901
Estrogen regulation and ion dependence of taurine uptake by MCF-7 human breast cancer cells. Cellular & molecular biology letters 20070901
Antioxidant defenses preserve membrane transport activity in Chironomus riparius larvae exposed to anoxia. Archives of insect biochemistry and physiology 20070801
Development of micellar electro kinetic chromatography for the separation and quantitation of L-valine, L-leucine, L-isoleucin and L-phenylalanine in human plasma and comparison with HPLC. Pakistan journal of biological sciences : PJBS 20070801
Modification of fetal plasma amino acid composition by placental amino acid exchangers in vitro. The Journal of physiology 20070715
Amino acid changes within antenna helix are responsible for different regulatory preferences of human glutamate dehydrogenase isozymes. The Journal of biological chemistry 20070706
Spectral characterization of novel ternary zinc(II) complexes containing 1,10-phenanthroline and Schiff bases derived from amino acids and salicylaldehyde-5-sulfonates. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070701
L-glutamine in vitro regulates rat aortic glutamate content and modulates nitric oxide formation and contractility responses. American journal of physiology. Cell physiology 20070701
Physical characteristics and aerosolization performance of insulin dry powders for inhalation prepared by a spray drying method. The Journal of pharmacy and pharmacology 20070701
Effects of leucine and phenylalanine supplementation during intermittent periods of food restriction and refeeding in adult rats. Life sciences 20070613
Tautomeric and microscopic protonation equilibria of some alpha-amino acids. Analytical biochemistry 20070601
Polymeric alkenoxy amino acid surfactants: V. Comparison of carboxylate and sulfate head group polymeric surfactants for enantioseparation in MEKC. Electrophoresis 20070601
The promoter activity of isovaleryl-CoA dehydrogenase-encoding gene (ivdA) from Aspergillus oryzae is strictly repressed by glutamic acid. Bioscience, biotechnology, and biochemistry 20070601
The structure and transcriptional analysis of a global regulator from Neisseria meningitidis. The Journal of biological chemistry 20070511
Inhibitory effect of TNF-alpha on the intestinal absorption of galactose. Journal of cellular biochemistry 20070501
Properties and molecular evolution of human GLUD2 (neural and testicular tissue-specific) glutamate dehydrogenase. Journal of neuroscience research 20070401
Combination of amino acids reduces pigmentation in B16F0 melanoma cells. Biological & pharmaceutical bulletin 20070401
[Pathway analysis for production of L-leucine by Brevibacterium flavum TK0303]. Wei sheng wu xue bao = Acta microbiologica Sinica 20070401
Vibrational analysis of amino acids and short peptides in hydrated media. I. L-glycine and L-leucine. The journal of physical chemistry. B 20070215
Intestinal D-galactose transport in an endotoxemia model in the rabbit. The Journal of membrane biology 20070201
A cysteine proteinase in the penetration glands of the cercariae of Tylodelphys excavata (Trematoda, Diplostomidae). Parasitology research 20070101
Initial experience with the radiotracer anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid with PET/CT in prostate carcinoma. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20070101
Spatial and sex-specific dissection of the Anopheles gambiae midgut transcriptome. BMC genomics 20070101
Strategy of transcription regulation in the budding yeast. PloS one 20070101
Regulation of metabolic networks by small molecule metabolites. BMC bioinformatics 20070101
Central administration of dipeptides, beta-alanyl-BCAAs, induces hyperactivity in chicks. BMC neuroscience 20070101
Cation induced differential effect on structural and functional properties of Mycobacterium tuberculosis alpha-isopropylmalate synthase. BMC structural biology 20070101
High susceptibility of Bt maize to aphids enhances the performance of parasitoids of lepidopteran pests. PloS one 20070101
Bacillus anthracis secretome time course under host-simulated conditions and identification of immunogenic proteins. Proteome science 20070101
[Biologically active substances in grated cocoa and cocoa butter]. Voprosy pitaniia 20070101
Overexpression of non-functional LAT1/4F2hc in renal proximal tubular epithelial cells from the spontaneous hypertensive rat. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101
The effects of short-term alpha-ketoisocaproic acid supplementation on exercise performance: a randomized controlled trial. Journal of the International Society of Sports Nutrition 20070101
Genetic subtraction profiling identifies genes essential for Arabidopsis reproduction and reveals interaction between the female gametophyte and the maternal sporophyte. Genome biology 20070101
Inhibition of protein aggregation: supramolecular assemblies of arginine hold the key. PloS one 20070101
Modulation of the cationic amino acid transport system y+L by surface potential, ouabain and thrombin in human platelets: effects of uremia. Nephron. Experimental nephrology 20070101
Serotonin differentially regulates short- and long-term prediction of rewards in the ventral and dorsal striatum. PloS one 20070101
Gender affects 13C-ketoisocaproic acid breath test. European review for medical and pharmacological sciences 20070101
Membrane transport function in primary cultures of human proximal tubular cells. Toxicology 20061207
Protease and esterase activity of staphylococci. International journal of food microbiology 20061201
Oxo-4-methylpentanoic acid directs the metabolism of GABA into the Krebs cycle in rat pancreatic islets. The Biochemical journal 20061115
L-proline transport by purified cell types of lobster hepatopancreas. Journal of experimental zoology. Part A, Comparative experimental biology 20061001
A leuC mutation leading to increased L-lysine production and rel-independent global expression changes in Corynebacterium glutamicum. Applied microbiology and biotechnology 20061001
The PKA-CREB system encoded by the honeybee genome. Insect molecular biology 20061001
Stereoselective allyl transfer to chiral alpha-methoxycarbaldehydes: a model study related to the C-9/C-15 fragment of geldanamycin. Bioorganic & medicinal chemistry 20060915
y+ LAT-1 mediates transport of the potent and selective iNOS inhibitor, GW274150, in control J774 macrophages. Amino acids 20060901
Deuterium isotope effect on 13C chemical shifts of tetrabutylammonium salts of Schiff bases amino acids. Magnetic resonance in chemistry : MRC 20060901
Bitterness suppression of BCAA solutions by L-ornithine. Chemical & pharmaceutical bulletin 20060901
Electrocatalytic oxidation and highly selective voltammetric determination of L-cysteine at the surface of a 1-[4-(ferrocenyl ethynyl)phenyl]-1-ethanone modified carbon paste electrode. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20060901
Amino acids as modulators of endothelium-derived nitric oxide. American journal of physiology. Renal physiology 20060801
Characterization of cationic amino acid transport systems in rat erythrocytes: lack of effect of uraemia on L-arginine influx. Clinical and experimental pharmacology & physiology 20060801
Isolation and identification of the icosalides--cyclic peptolides with selective antibiotic and cytotoxic activities. The Journal of antibiotics 20060801
Kinetic and chemical mechanism of alpha-isopropylmalate synthase from Mycobacterium tuberculosis. Biochemistry 20060725
Exploring the ability of frozen-density embedding to model induced circular dichroism. The journal of physical chemistry. A 20060720
Effects of tetrabromobisphenol A on larval development and thyroid hormone-regulated biomarkers of the amphibian Xenopus laevis. Environmental research 20060701
Study of electrolyte induced aggregation of gold nanoparticles capped by amino acids. Journal of colloid and interface science 20060701
Synthesis, helicity, and chromism of optically active poly(phenylacetylene)s carrying different amino acid moieties and pendant terminal groups. The journal of physical chemistry. B 20060615
Lanthanum(III) and praseodymium(III) derivatives with dithiocarbamates derived from alpha-amino acids. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060601
Characterization of the initial enzymatic steps of barbamide biosynthesis. Journal of natural products 20060601
Possible involvement of calcium signaling pathways in L-leucine-stimulated protein synthesis in L6 myotubes. Bioscience, biotechnology, and biochemistry 20060601
[Obesity and progression of chronic renal insufficiency: a Czech long term prospective double-blind randomised multicentre study]. Vnitrni lekarstvi 20060601
Alkaline Phosphatases : Structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes. Purinergic signalling 20060601
Synthesis and evaluation of potent, highly-selective, 3-aryl-piperazinone inhibitors of protein geranylgeranyltransferase-I. Organic & biomolecular chemistry 20060507
Effects of leucine supplementation on the body composition and protein status of rats submitted to food restriction. Nutrition (Burbank, Los Angeles County, Calif.) 20060501
Leptin biosynthetic pathway in white adipocytes. Biochemistry and cell biology = Biochimie et biologie cellulaire 20060401
Adenine nucleotide pattern in rat pancreatic islets exposed to nutrient secretagogues. Endocrine 20060401
Carbon catabolite repression regulates amino acid permeases in Saccharomyces cerevisiae via the TOR signaling pathway. The Journal of biological chemistry 20060303
A combined 17O RAPT and MQ-MAS NMR study of L-leucine. Solid state nuclear magnetic resonance 20060201
Quantification of trimethylsilyl derivatives of amino acid disease biomarkers in neonatal blood samples by gas chromatography-mass spectrometry. Analytical and bioanalytical chemistry 20060201
Estrogen-like activity of seafood related to environmental chemical contaminants. Environmental health : a global access science source 20060101
Integrative investigation of metabolic and transcriptomic data. BMC bioinformatics 20060101
Identification of a Bacillus thuringiensis Cry11Ba toxin-binding aminopeptidase from the mosquito, Anopheles quadrimaculatus. BMC biochemistry 20060101
The influence of tumor oxygenation on (18)F-FDG (fluorine-18 deoxyglucose) uptake: a mouse study using positron emission tomography (PET). Radiation oncology (London, England) 20060101
Brefeldin A decreases the activity of the general amino acid permease (GAP1) and the more specific systems for L-leucine uptake in Saccharomyces cerevisiae. Cellular & molecular biology letters 20060101
Purification and characterization of a halotolerant intracellular protease from Bacillus subtilis strain FP-133. Journal of basic microbiology 20060101
'Nutritional and chemopreventive anti-cancer agents up-regulate expression of p27Kip1, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells'. Cancer cell international 20060101
High-resolution quantitative imaging of mammalian and bacterial cells using stable isotope mass spectrometry. Journal of biology 20060101
Optimization of formulation components and characterization of large respirable powders containing high therapeutic payload. Pharmaceutical development and technology 20060101
Restructuring of pancreatic islets and insulin secretion in a postnatal critical window. PloS one 20060101
Part III: Surface-enhanced Raman scattering of amino acids and their homodipeptide monolayers deposited onto colloidal gold surface. Applied spectroscopy 20051201
L-type amino acids stimulate gastric acid secretion by activation of the calcium-sensing receptor in parietal cells. American journal of physiology. Gastrointestinal and liver physiology 20051001
Isolation and functional characterization of a novel organic solute carrier protein, hOSCP1. The Journal of biological chemistry 20050916
Expression and function of LAT1, a neutral amino acid exchanger, in renal porcine epithelial cell line LLC-PK. Acta physiologica Scandinavica 20050901
Cyanopeptolin 954, a chlorine-containing chymotrypsin inhibitor of Microcystis aeruginosa NIVA Cya 43. Journal of natural products 20050901
Stereoselective synthesis of constrained azacyclic hydroxyethylene isosteres as aspartic protease inhibitors: dipolar cycloaddition and related methodologies toward branched pyrrolidine and pyrrolidinone carboxylic acids. The Journal of organic chemistry 20050819
Surface properties of aqueous amino acid solutions II. Leucine-leucine hydrochloride and leucine-sodium leucinate mixtures. Journal of colloid and interface science 20050815
Mouse oocytes regulate metabolic cooperativity between granulosa cells and oocytes: amino acid transport. Biology of reproduction 20050801
Synthesis and X-ray crystal structure study of the hydroxyurea and hydantoin derivatives of L-valine. The journal of peptide research : official journal of the American Peptide Society 20050801
alpha-Aminoalkylphosphonates as a tool in experimental optimisation of P1 side chain shape of potential inhibitors in S1 pocket of leucine- and neutral aminopeptidases. European journal of medicinal chemistry 20050801
Demonstration of kynurenine aminotransferases I and II and characterization of kynurenic acid synthesis in oligodendrocyte cell line (OLN-93). Neurochemical research 20050801
Slow-onset feedback inhibition: inhibition of Mycobacterium tuberculosis alpha-isopropylmalate synthase by L-leucine. Journal of the American Chemical Society 20050720
Homocysteine, a risk factor for atherosclerosis, biphasically changes the endothelial production of kynurenic acid. European journal of pharmacology 20050711
Regulation of leptin secretion from white adipocytes by insulin, glycolytic substrates, and amino acids. American journal of physiology. Endocrinology and metabolism 20050701
Nephrotoxicity of organic solvents: biomarkers for early detection. International archives of occupational and environmental health 20050701
L-type amino acid transporter 1-mediated L-leucine transport at the inner blood-retinal barrier. Investigative ophthalmology & visual science 20050701
Asp578 in LEU4p is one of the key residues for leucine feedback inhibition release in sake yeast. Bioscience, biotechnology, and biochemistry 20050701
Influence of leucine and valine on ramoplanin production by Actinoplanes sp. ATCC 33076. The Journal of antibiotics 20050701
Studies on the application of immobilization technique for the production of cyclosporin A by a local strain of Aspergillus terreus. The Journal of general and applied microbiology 20050601
Alkaline phosphatase retained in HepG2 hepatocarcinoma cells vs. alkaline phosphatase released to culture medium: difference of aberrant glycosylation. Biochemical and biophysical research communications 20050506
Characterization and microbial utilization of dissolved organic carbon in groundwater contaminated with chlorophenols. Chemosphere 20050501
A mathematical model for the branched chain amino acid biosynthetic pathways of Escherichia coli K12. The Journal of biological chemistry 20050325
Quantitative analysis of enalapril by 1H NMR spectroscopy in tablets. Journal of pharmaceutical and biomedical analysis 20050309
Molecular recognition of alpha-cyclodextrin (CD) to choral amino acids based on methyl orange as a molecular probe. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050301
Effect of hyperglycaemic load on maternal-foetal transport of L-leucine in perfused human placental lobule: in vitro study. Acta diabetologica 20050301
Testing the hypothesis that system y(+)L accounts for high- and low-transport phenotypes in chicken erythrocytes using L-leucine as substrate. The Journal of membrane biology 20050301
Dual effect of DL-homocysteine and S-adenosylhomocysteine on brain synthesis of the glutamate receptor antagonist, kynurenic acid. Journal of neuroscience research 20050201
A biosynthetic pathway to isovaleryl-CoA in myxobacteria: the involvement of the mevalonate pathway. Chembiochem : a European journal of chemical biology 20050201
Improved production of isoamyl acetate by a sake yeast mutant resistant to an isoprenoid analog and its dependence on alcohol acetyltransferase activity, but not on isoamyl alcohol production. Journal of bioscience and bioengineering 20050201
Comparison of the structure of key variants of microcystin to vasopressin. Environmental toxicology and pharmacology 20050201
The novel L- and D-amino acid derivatives of hydroxyurea and hydantoins: synthesis, X-ray crystal structure study, and cytostatic and antiviral activity evaluations. Journal of medicinal chemistry 20050127
Glutamine is a key regulator for amino acid-controlled cell growth through the mTOR signaling pathway in rat intestinal epithelial cells. Biochemical and biophysical research communications 20050107
Molecular basis of human glutamate dehydrogenase regulation under changing energy demands. Journal of neuroscience research 20050101
Alterations of insulin secretion following long-term manipulation of ATP-sensitive potassium channels by diazoxide and nateglinide. Biochemical pharmacology 20050101
3H-L-histidine and 65Zn(2+) are cotransported by a dipeptide transport system in intestine of lobster Homarus americanus. The Journal of experimental biology 20050101
Transfection activity of polyamidoamine dendrimers having hydrophobic amino acid residues in the periphery. Bioconjugate chemistry 20050101
Gluten-free diet may alleviate depressive and behavioural symptoms in adolescents with coeliac disease: a prospective follow-up case-series study. BMC psychiatry 20050101
Evidence for functional asymmetry in the olfactory system of the Senegalese sole (Solea senegalensis). Physiological and biochemical zoology : PBZ 20050101
Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with Rin. BMC neuroscience 20050101
Whole cell matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and in situ structure analysis of streptocidins, a family of tyrocidine-like cyclic peptides. Rapid communications in mass spectrometry : RCM 20050101
Effect of individual amino acids and glucose on activation and germination of Rhizopus oligosporus sporangiospores in tempe starter. Journal of applied microbiology 20050101
Studies of the intermediary metabolism in cultured cells of the insect Spodoptera frugiperda using 13C- or 15N-labelled tracers. BMC biochemistry 20050101
l-leucine aminopeptidase production by filamentous Aspergillus fungi. Letters in applied microbiology 20050101
Generation of functional HLA-DR*1101 tetramers receptive for loading with pathogen- or tumour-derived synthetic peptides. BMC immunology 20050101
Targeting the active site of the placental isozyme of alkaline phosphatase by phage-displayed scFv antibodies selected by a specific uncompetitive inhibitor. BMC biotechnology 20050101
Pt based enzyme electrode probes assembled with Prussian Blue and conducting polymer nanostructures. Biosensors & bioelectronics 20041215
Right-handed helical structure of expanded oligo(L-leucine) containing [Ru(terpyridine)2]2+ moieties. Journal of the American Chemical Society 20041215
Effects of amino acids and its metabolites on prolidase activity against various iminodipeptides in erythrocytes from normal human and a patient with prolidase deficiency. Clinica chimica acta; international journal of clinical chemistry 20041201
The effect of vehicle on physical properties and aerosolisation behaviour of disodium cromoglycate microparticles spray dried alone or with L-leucine. International journal of pharmaceutics 20041105
Foxl1 null mice have abnormal intestinal epithelia, postnatal growth retardation, and defective intestinal glucose uptake. American journal of physiology. Gastrointestinal and liver physiology 20041001
Atmospheric oxygen and other conditions affecting the production of cereulide by Bacillus cereus in food. International journal of food microbiology 20041001
Cloning and gene silencing of LAT2, the L-3,4-dihydroxyphenylalanine (L-DOPA) transporter, in pig renal LLC-PK1 epithelial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20041001
Prolonged oral treatment with an essential amino acid L-leucine does not affect female reproductive function and embryo-fetal development in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040901
A critical regulatory role of leucin zipper transcription factor c-Maf in Th1-mediated experimental colitis. Journal of immunology (Baltimore, Md. : 1950) 20040901
Maternal-fetal transport kinetics of L-Leucine in vitro in gestational diabetic pregnancies. Diabetes & metabolism 20040901
L-leucine transport in human breast cancer cells (MCF-7 and MDA-MB-231): kinetics, regulation by estrogen and molecular identity of the transporter. Biochimica et biophysica acta 20040830
Examination of the rate of peptide biosynthesis in neuroendocrine cell lines using a stable isotopic label and mass spectrometry. Journal of neurochemistry 20040801
High- and low-affinity transport of L-leucine and L-DOPA by the hetero amino acid exchangers LAT1 and LAT2 in LLC-PK1 renal cells. American journal of physiology. Renal physiology 20040801
INFgamma stimulates arginine transport through system y+L in human monocytes. FEBS letters 20040730
Novel dual inhibitors of calpain and lipid peroxidation. Bioorganic & medicinal chemistry letters 20040716
Quercetin glucosides inhibit glucose uptake into brush-border-membrane vesicles of porcine jejunum. The British journal of nutrition 20040601
Conversion into GABA (gamma-aminobutyric acid) may reduce the capacity of L-glutamine as an insulin secretagogue. The Biochemical journal 20040501
Tacrolimus impairment of insulin secretion in isolated rat islets occurs at multiple distal sites in stimulus-secretion coupling. Endocrinology 20040501
Purification, partial characterization, crystallization and structural determination of AHP-LAAO, a novel L-amino-acid oxidase with cell apoptosis-inducing activity from Agkistrodon halys pallas venom. Acta crystallographica. Section D, Biological crystallography 20040501
Part I: surface-enhanced Raman spectroscopy investigation of amino acids and their homodipeptides adsorbed on colloidal silver. Applied spectroscopy 20040501
Part II: surface-enhanced Raman spectroscopy investigation of methionine containing heterodipeptides adsorbed on colloidal silver. Applied spectroscopy 20040501
Diversity of L-leucine catabolism in various microorganisms involved in dairy fermentations, and identification of the rate-controlling step in the formation of the potent flavour component 3-methylbutanal. Applied microbiology and biotechnology 20040401
Platelet-derived growth factor stimulates LAT1 gene expression in vascular smooth muscle: role in cell growth. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040401
Arginine and Leucine regulate p70 S6 kinase and 4E-BP1 in intestinal epithelial cells. International journal of molecular medicine 20040401
Effect of prenatal exposure to ethanol on postnatal development of intestinal transport functions in rats. European journal of nutrition 20040401
No evidence of Neandertal mtDNA contribution to early modern humans. PLoS biology 20040301
3-methylglutaconic aciduria type I in a boy with fever-associated seizures. Pediatric neurology 20040301
The present state of antineoplaston research (1). Integrative cancer therapies 20040301
Prodrugs of HIV protease inhibitors-saquinavir, indinavir and nelfinavir-derived from diglycerides or amino acids: synthesis, stability and anti-HIV activity. Organic & biomolecular chemistry 20040207
Insulin secretion profiles are modified by overexpression of glutamate dehydrogenase in pancreatic islets. Diabetologia 20040201
Spontaneous onset of homochirality in oligopeptide chains generated in the polymerization of N-carboxyanhydride amino acids in water. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20040201
Tissue-specific regulation of 4E-BP1 and S6K1 phosphorylation by alpha-ketoisocaproate. Journal of nutritional science and vitaminology 20040201
Cloning, sequencing, and biochemical characterization of the nostocyclopeptide biosynthetic gene cluster: molecular basis for imine macrocyclization. Gene 20040121
Selected amino acids, dipeptides and arylalkylamine derivatives do not act as allosteric modulators at GABAB receptors. European journal of pharmacology 20040112
Jejunal microvilli atrophy and reduced nutrient transport in rats with advanced liver cirrhosis: improvement by Insulin-like Growth Factor I. BMC gastroenterology 20040101
Thirteen-week oral toxicity study of branched-chain amino acids in rats. International journal of toxicology 20040101
External chirality-triggered helicity control promoted by introducing a beta-Ala residue into the N-terminus of chiral peptides. Biomacromolecules 20040101
Rapid determination of amino acids in neonatal blood samples based on derivatization with isobutyl chloroformate followed by solid-phase microextraction and gas chromatography/mass spectrometry. Rapid communications in mass spectrometry : RCM 20040101
Characteristics of prolinase against various iminodipeptides in erythrocyte lysates from a normal human and a patient with prolidase deficiency. Clinical chemistry and laboratory medicine 20040101
Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood-brain barrier model for drug uptake and transport studies. Brain research 20031114
Synthesis and activity of HCO-Met-Leu-Phe-OMe analogues containing beta-alanine or taurine at the central position. Farmaco (Societa chimica italiana : 1989) 20031101
Nitric oxide synthesis requires activity of the cationic and neutral amino acid transport system y+L in human umbilical vein endothelium. Experimental physiology 20031101
L-leucine methyl ester: the female-produced sex pheromone of the scarab beetle, Phyllophaga lanceolata. Journal of chemical ecology 20031101
Involvement of protein kinase C activation in L-leucine-induced stimulation of protein synthesis in l6 myotubes. Cytotechnology 20031101
Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters. The Journal of biological chemistry 20031031
Induction of oxidative stress in rat brain by the metabolites accumulating in maple syrup urine disease. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20031001
(19)F NMR studies of the leucine-isoleucine-valine binding protein: evidence that a closed conformation exists in solution. Journal of biomolecular structure & dynamics 20031001
Sublethal effects of copper on coho salmon: impacts on nonoverlapping receptor pathways in the peripheral olfactory nervous system. Environmental toxicology and chemistry 20031001
Effect of heavy metals on the uptake of [3H]-L-histidine by the polychaete Nereis succinea. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20031001
[Investigation of the influence of Fas antigen on Hep G2 cells, an erythropoietin producing cell line]. Nihon Jinzo Gakkai shi 20031001
Occurrence of two different glutamate dehydrogenase activities in the halophilic bacterium Salinibacter ruber. FEMS microbiology letters 20030912
Uptake of [3H]L-serine in rat brain synaptosomal fractions. Brain research 20030905
Expression and regulation of L-cystine transporter, system xc-, in the newly developed rat retinal Müller cell line (TR-MUL). Glia 20030901
Dietary protein reduction in sheep and goats: different effects on L-alanine and L-leucine transport across the brush-border membrane of jejunal enterocytes. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20030801
Diagnosis of maple syrup urine disease by determination of L-valine, L-isoleucine, L-leucine and L-phenylalanine in neonatal blood spots by gas chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030725
Manipulation of CD98 expression affects both trophoblast cell fusion and amino acid transport activity during syncytialization of human placental BeWo cells. The Journal of physiology 20030701
Regulation of L-leucine transport in rat kidney by dexamethasone and triiodothyronine. Amino acids 20030701
Sequence analysis and biochemical characterization of the nostopeptolide A biosynthetic gene cluster from Nostoc sp. GSV224. Gene 20030605
Regulatory effects of 5'-deoxypyridoxal on glutamate dehydrogenase activity and insulin secretion in pancreatic islets. Biochimie 20030601
Transport of L-arginine and nitric oxide formation in human platelets. European journal of biochemistry 20030501
High cell density cultivation of Brevibacterium linens and formation of proteinases and lipase. Biotechnology letters 20030501
L-phenylalanine selectively depresses currents at glutamatergic excitatory synapses. Journal of neuroscience research 20030401
Functional and molecular characteristics of system L in human breast cancer cells. Biochimica et biophysica acta 20030401
Spinal gabapentin and antinociception: mechanisms of action. Journal of Korean medical science 20030401
A comparative study on the rectal aminopeptidase enzymatic activities of different species. Die Pharmazie 20030301
[Preparation and pharmaceutical properties of salcatonin dry powder inhalations]. Yao xue xue bao = Acta pharmaceutica Sinica 20030301
Inhibition of amino acid-mTOR signaling by a leucine derivative induces G1 arrest in Jurkat cells. Biochemical and biophysical research communications 20030207
Increased nitric oxide synthesis in uraemic platelets is dependent on L-arginine transport via system y(+)L. Pflugers Archiv : European journal of physiology 20030201
Development of an orexin-2 receptor selective agonist, [Ala(11), D-Leu(15)]orexin-B. Bioorganic & medicinal chemistry letters 20030106
Involvement of the system L amino acid transporter on uptake of S-nitroso-L-cysteine, an endogenous S-nitrosothiol, in PC12 cells. European journal of pharmacology 20030101
Noncovalent chiral domino effect on one-handed helix of nonapeptide containing a midpoint L-residue. Biomacromolecules 20030101
Kynurenate production by cultured human astrocytes. Journal of neural transmission (Vienna, Austria : 1996) 20030101
Proteolytic activity of a yeast cell wall lytic Arthrobacter species. Letters in applied microbiology 20030101
Study of structure-function relationships in human glutamate dehydrogenases reveals novel molecular mechanisms for the regulation of the nerve tissue-specific (GLUD2) isoenzyme. Neurochemistry international 20030101
Effects of acute tryptophan depletion on executive function in healthy male volunteers. BMC psychiatry 20030101
Amino acids for amyotrophic lateral sclerosis / motor neuron disease. The Cochrane database of systematic reviews 20030101
Kinetics of sequential metabolism from D-leucine to L-leucine via alpha-ketoisocaproic acid in rat. Drug metabolism and disposition: the biological fate of chemicals 20021201
Monitoring the structural consequences of Phe12-->D-Phe and Leu15-->Aib substitution in human/rat corticotropin releasing hormone. Implications for design of CRH antagonists. European journal of biochemistry 20021201
Biochemical characterization of the soluble alkaline phosphatase isolated from the venomous snake W. aegyptia. Journal of natural toxins 20021201
Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the activation of the enzyme by ADP and L-leucine. The Journal of biological chemistry 20021129
Protective effect of D-glucose, L-leucine and fetal calf serum against oxidative stress in neonatal pancreatic islets. Biochimica et biophysica acta 20021120
Prediction of the bitterness of single, binary- and multiple-component amino acid solutions using a taste sensor. International journal of pharmaceutics 20021106
19F NMR study of the leucine-specific binding protein of Escherichia coli: mutagenesis and assignment of the 5-fluorotryptophan-labeled residues. Protein engineering 20021101
Possible involvement of phospholipase C and protein kinase C in stimulatory actions of L-leucine and its keto acid, alpha-ketoisocaproic acid, on protein synthesis in RLC-16 hepatocytes. Cytotechnology 20021101
Synthesis and conformational analysis of small peptides containing 6-endo-BT(t)L scaffolds as reverse turn mimetics. The Journal of organic chemistry 20021018
The stimulus-secretion coupling of amino acid-induced insulin release. Insulinotropic action of L-alanine. Biochimica et biophysica acta 20021010
Studies on the macroscopic protonation constants of some alpha-amino acids in ethanol-water mixtures. Analytical biochemistry 20021001
[Studies on the cytological function of the biomembrane and the neurons]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20021001
Cloning and characterization of an aromatic amino acid and leucine permease of Penicillium chrysogenum. Biochimica et biophysica acta 20020920
Anti-AIDS agents 49. Synthesis, anti-HIV, and anti-fusion activities of IC9564 analogues based on betulinic acid. Journal of medicinal chemistry 20020912
Lysine uptake by cloned hCAT-2B: comparison with hCAT-1 and with trophoblast surface membranes. The Journal of membrane biology 20020901
A continuous 96-well plate spectrophotometric assay for branched-chain amino acid aminotransferases. Analytical biochemistry 20020901
The barbamide biosynthetic gene cluster: a novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit. Gene 20020821
A study of L-leucine, L-phenylalanine and L-alanine transport in the perfused rat mammary gland: possible involvement of LAT1 and LAT2. Biochimica et biophysica acta 20020819
Peroxynitrite stimulates L-arginine transport system y(+) in glial cells. A potential mechanism for replenishing neuronal L-arginine. The Journal of biological chemistry 20020816
Glial induction of blood-brain barrier-like L-system amino acid transport in the ECV304 cell line. Glia 20020801
Genetic and physiological analysis of branched-chain alcohols and isoamyl acetate production in Saccharomyces cerevisiae. Applied microbiology and biotechnology 20020801
Effects of epidermal growth factor on placental amino acids uptake in pregnant rats. The Journal of veterinary medical science 20020801
Epithelial cells isolated from chicken jejunum: an experimental model for the study of the functional properties of amino acid transport system b(0,+). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20020701
Oral amino-acid provision does not affect muscle strength or size gains in older men. Medicine and science in sports and exercise 20020701
Thermodynamic quantities of surface formation of aqueous electrolyte solutions. V. Aqueous solutions of aliphatic amino acids. Journal of colloid and interface science 20020615
Tumor necrosis factor-alpha mediates inhibitory effect of lipopolysaccharide on L-leucine intestinal uptake. Digestive diseases and sciences 20020601
Evaluation of the RBE4 cell line to explore carrier-mediated drug delivery to the CNS via the L-system amino acid transporter at the blood-brain barrier. Journal of drug targeting 20020601
Synthesis and anti-Helicobacter pylori activity of pyloricidin derivatives II. The combination of amino acid residues in the dipeptidic moiety and its effect on the anti-Helicobacter pylori activity. The Journal of antibiotics 20020501
NMR diffusion as a novel tool for measuring the association constant between cyclodextrin and guest molecules. Carbohydrate research 20020430
The L-3,4-dihydroxyphenylalanine transporter in human and rat epithelial intestinal cells is a type 2 hetero amino acid exchanger. European journal of pharmacology 20020426
Tumor necrosis factor alpha stimulates taurine uptake and transporter gene expression in human intestinal Caco-2 cells. FEBS letters 20020424
Stabilization of neurotensin analogues: effect on peptide catabolism, biodistribution and tumor binding. Nuclear medicine and biology 20020401
Protein phosphatase type 1 regulates ion homeostasis in Saccharomyces cerevisiae. Genetics 20020401
Na+-independent transporters, LAT-2 and b0,+, exchange L-DOPA with neutral and basic amino acids in two clonal renal cell lines. The Journal of membrane biology 20020315
Aortic leucine-to-glutamate pathway: metabolic route and regulation of contractile responses. American journal of physiology. Heart and circulatory physiology 20020301
Stimulation of lipid peroxidation in vitro in rat brain by the metabolites accumulating in maple syrup urine disease. Metabolic brain disease 20020301
Effects of cytochalasin B and D upon insulin release and pancreatic islet cell metabolism. International journal of molecular medicine 20020201
Oral administration of leucine stimulates phosphorylation of 4E-bP1 and S6K 1 in skeletal muscle but not in liver of diabetic rats. Journal of nutritional science and vitaminology 20020201
Exploring the interest of 1,2-dithiolane ring system in peptide chemistry. Synthesis of a chemotactic tripeptide and x-ray crystal structure of a 4-amino-1,2-dithiolane-4-carboxylic acid derivative. Bioorganic & medicinal chemistry 20020101
Two-way arginine transport in human endothelial cells: TNF-alpha stimulation is restricted to system y(+). American journal of physiology. Cell physiology 20020101
β-Adrenergics enhance brain extraction of levodopa. Movement disorders : official journal of the Movement Disorder Society 20020101
Effects of leucine supplemented diet on intestinal absorption in tumor bearing pregnant rats. BMC cancer 20020101
Structure of the Lrp-regulated serA promoter of Escherichia coli K-12. Molecular microbiology 20020101
Cellular mechanism underlying LPS-induced inhibition of in vitro L-leucine transport across rabbit jejunum. Journal of endotoxin research 20020101
Synthesis and asymmetric reducing performance of chitin/dihydronicotinamide conjugates having glycine or L-leucine spacer arms. Biomacromolecules 20020101
The administration of lipopolysaccharide, in vivo, induces alteration in L-leucine intestinal absorption. Life sciences 20011228
Myc/Max/Mad regulate the frequency but not the duration of productive cell cycles. EMBO reports 20011215
Regulation of human glutamate dehydrogenases: implications for glutamate, ammonia and energy metabolism in brain. Journal of neuroscience research 20011201
Determination of free D-proline and D-leucine in the brains of mutant mice lacking D-amino acid oxidase activity. Analytical biochemistry 20011115
Analysis of conformationally restricted alpha-ketoglutarate analogues as substrates of dehydrogenases and aminotransferases. Analytical biochemistry 20011115
Chiral analysis of amino acids using electrochemical composite bienzyme biosensors. Analytical biochemistry 20011115
Conversion of a glutamate dehydrogenase into methionine/norleucine dehydrogenase by site-directed mutagenesis. European journal of biochemistry 20011101
Comparison of vaginal aminopeptidase enzymatic activities in various animals and in humans. The Journal of pharmacy and pharmacology 20011101
Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines. Biochimica et biophysica acta 20011001
Leucine transport in membrane vesicles from Chironomus riparius larvae displays a mélange of crown-group features. Archives of insect biochemistry and physiology 20011001
System y+L-like activities account for high and low amino-acid transport phenotypes in chicken erythrocytes. The Journal of membrane biology 20011001
Possible involvement of amino acid transporters on S-nitroso-cysteine-induced inhibition of arachidonic acid release in PC12 cells. Neuroscience letters 20010928
Molecular events involved in up-regulating human Na+-independent neutral amino acid transporter LAT1 during T-cell activation. The Biochemical journal 20010915
Amino acid supplementation affects hematological and biochemical parameters in elite rugby players. Bioscience, biotechnology, and biochemistry 20010901
Effects of ADP on different inhibitory properties of brain glutamate dehydrogenase isoproteins by perphenazine. Biochimie 20010901
The stability constants of copper(II) complexes with some alpha-amino acids in dioxan-water mixtures. Analytical biochemistry 20010815
Synthesis of natural flutimide and analogous fully substituted pyrazine-2,6-diones, endonuclease inhibitors of influenza virus. The Journal of organic chemistry 20010810
Psychrophilic valine dehydrogenase of the antarctic psychrophile, Cytophaga sp. KUC-1: purification, molecular characterization and expression. European journal of biochemistry 20010801
Acute insulin responses to leucine in children with the hyperinsulinism/hyperammonemia syndrome. The Journal of clinical endocrinology and metabolism 20010801
Production of pyridoxal phosphate by a mutant strain of Schizosaccharomyces pombe. Bioscience, biotechnology, and biochemistry 20010801
Time course of leucine-induced 4E-BP1 and S6K1 phosphorylation in the liver and skeletal muscle of rats. Journal of nutritional science and vitaminology 20010801
Comparison of monomeric and polymeric amino acid based surfactants for chiral separations. Journal of chromatography. A 20010713
Influence of neutral cyclodextrin concentration on plate numbers in capillary electrophoresis. Electrophoresis 20010601
Synthesis and characterization of N,N-dichlorinated amino acids: taurine, homotaurine, GABA and L-leucine. Neurochemical research 20010601
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. The Journal of biological chemistry 20010518
Reduction of large neutral amino acid levels in plasma and brain of hyperleucinemic rats. Neurochemistry international 20010501
Whole-body L-leucine oxidation in patients with variant form of maple syrup urine disease. Pediatric research 20010501
Effect of lipopolysaccharide on small intestinal L-leucine transport in rabbit. Digestive diseases and sciences 20010501
L-leucine transport in rat heart under normal conditions and effects of a simulated hypoxia. Molecular and cellular biochemistry 20010501
Characterisation of L-tryptophan transporters in human placenta: a comparison of brush border and basal membrane vesicles. The Journal of physiology 20010301
Effect of a leucine-supplemented diet on body composition changes in pregnant rats bearing Walker 256 tumor. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20010301
[Enantioseparation of twelve pharmaceutical racemates with high performance capillary electrophoresis using L-leucine as chiral selector]. Se pu = Chinese journal of chromatography 20010301
Fragmentary form of thermostable leucine dehydrogenase of Bacillus stearothermophilus: its construction and reconstitution of active fragmentary enzyme. Biochemical and biophysical research communications 20010202
Molecular characterization of L-amino acid oxidase from Agkistrodon halys blomhoffii with special reference to platelet aggregation. Biochimica et biophysica acta 20010112
Effects of vitamins on hepatic nuclear binding of L-tryptophan. Amino acids 20010101
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