Home Nitros Quinoline, 4-nitro-

Quinoline, 4-nitro-

CAS No.:
3741-15-9
Catalog Number:
AG0079RO
Molecular Formula:
C9H6N2O2
Molecular Weight:
174.1561
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
Product Description
Catalog Number:
AG0079RO
Chemical Name:
Quinoline, 4-nitro-
CAS Number:
3741-15-9
Molecular Formula:
C9H6N2O2
Molecular Weight:
174.1561
MDL Number:
MFCD01685427
IUPAC Name:
4-nitroquinoline
InChI:
InChI=1S/C9H6N2O2/c12-11(13)9-5-6-10-8-4-2-1-3-7(8)9/h1-6H
InChI Key:
ZPVSFHWMXABGPU-UHFFFAOYSA-N
SMILES:
[O-][N+](=O)c1ccnc2c1cccc2
Properties
Complexity:
202  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
174.043g/mol
Formal Charge:
0
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
174.159g/mol
Monoisotopic Mass:
174.043g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
58.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.1  
Literature
Title Journal
Phenolic extracts of brewers' spent grain (BSG) as functional ingredients - assessment of their DNA protective effect against oxidant-induced DNA single strand breaks in U937 cells. Food chemistry 20120915
Early induction of cytokines/cytokine receptors and Cox2, and activation of NF-κB in 4-nitroquinoline 1-oxide-induced murine oral cancer model. Toxicology and applied pharmacology 20120715
Homeobox C5 expression is associated with the progression of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20120701
Administration of a vaccine composed of dendritic cells pulsed with premalignant oral lesion lysate to mice bearing carcinogen-induced premalignant oral lesions stimulates a protective immune response. International immunopharmacology 20120701
Characterization of the evolution of immune phenotype during the development and progression of squamous cell carcinoma of the head and neck. Cancer immunology, immunotherapy : CII 20120601
Chemopreventive efficacy of Targretin in rodent models of urinary bladder, colon/intestine, head and neck and mammary cancers. Oncology reports 20120501
Alkylation-induced genotoxicity as a predictor of DNA repair deficiency following experimental oral carcinogenesis. Journal of molecular histology 20120401
The in vitro toxicology of Swedish snus. Critical reviews in toxicology 20120401
Identification of novel human damage response proteins targeted through yeast orthology. PloS one 20120101
Methylation-mediated molecular dysregulation in clinical oral malignancy. Journal of oncology 20120101
Topical polyethylene glycol as a novel chemopreventive agent for oral cancer via targeting of epidermal growth factor response. PloS one 20120101
Notch receptor inhibition reveals the importance of cyclin D1 and Wnt signaling in invasive esophageal squamous cell carcinoma. American journal of cancer research 20120101
Green tea polyphenol protection against 4-nitroquinoline 1-oxide-induced bone marrow lipid peroxidation and genotoxicity in Wistar rats. Asian Pacific journal of cancer prevention : APJCP 20120101
Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation. Oncotarget 20111201
Genistein, isoflavonoids in soybeans, prevents the formation of excess radiation-induced centrosomes via p21 up-regulation. Mutation research 20111101
An intranucleolar body associated with rDNA. Chromosoma 20111001
Bioanalytical tools for the evaluation of organic micropollutants during sewage treatment, water recycling and drinking water generation. Water research 20110801
Zinc deficiency activates S100A8 inflammation in the absence of COX-2 and promotes murine oral-esophageal tumor progression. International journal of cancer 20110715
The role of the TP53 gene during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20110701
Are luminescent bacteria suitable for online detection and monitoring of toxic compounds in drinking water and its sources? Analytical and bioanalytical chemistry 20110501
Ixr1 is required for the expression of the ribonucleotide reductase Rnr1 and maintenance of dNTP pools. PLoS genetics 20110501
Antiproliferative and anticytotoxic effects of cell fractions and exopolysaccharides from Lactobacillus casei 01. Mutation research 20110403
Fenofibrate exhibits a high potential to suppress the formation of squamous cell carcinoma in an oral-specific 4-nitroquinoline 1-oxide/arecoline mouse model. Biochimica et biophysica acta 20110401
Ras gene mutation is not related to tumour invasion during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20110401
Zinc supplementation suppresses 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis. Carcinogenesis 20110401
Oxidative DNA damage is a preliminary step during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. Journal of molecular histology 20110401
An active site aromatic triad in Escherichia coli DNA Pol IV coordinates cell survival and mutagenesis in different DNA damaging agents. PloS one 20110101
Oral carcinogenesis and oral cancer chemoprevention: a review. Pathology research international 20110101
Evaluation of cytotoxicity and genotoxicity of some Philippine medicinal plants. Pharmacognosy magazine 20110101
DNA-PK-dependent RPA2 hyperphosphorylation facilitates DNA repair and suppresses sister chromatid exchange. PloS one 20110101
Understanding carcinogenesis for fighting oral cancer. Journal of oncology 20110101
The peptidyl prolyl isomerase Rrd1 regulates the elongation of RNA polymerase II during transcriptional stresses. PloS one 20110101
Association of alpha B-crystallin genotypes with oral cancer susceptibility, survival, and recurrence in Taiwan. PloS one 20110101
The chemopreventive properties and therapeutic modulation of green tea polyphenols in oral squamous cell carcinoma. ISRN oncology 20110101
Flavonoids: A versatile source of anticancer drugs. Pharmacognosy reviews 20110101
Differential modifying effects of food additive butylated hydroxytoluene toward radiation and 4-nitro-quinoline 1-oxide-induced genotoxicity in yeast. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20110101
Cancer chemopreventive ability of conjugated linolenic acids. International journal of molecular sciences 20110101
Potential of herbs in skin protection from ultraviolet radiation. Pharmacognosy reviews 20110101
Functionally Relevant Residues of Cdr1p: A Multidrug ABC Transporter of Human Pathogenic Candida albicans. Journal of amino acids 20110101
Dual inhibition of vascular endothelial growth factor receptor and epidermal growth factor receptor is an effective chemopreventive strategy in the mouse 4-NQO model of oral carcinogenesis. Cancer prevention research (Philadelphia, Pa.) 20101101
Malignant transformation of rat bone marrow-derived mesenchymal stem cells treated with 4-nitroquinoline 1-oxide. Chemico-biological interactions 20101006
The Werner's Syndrome protein collaborates with REV1 to promote replication fork progression on damaged DNA. DNA repair 20101005
Oral carcinogenesis induced by 4-nitroquinoline 1-oxide in lecithin:retinol acyltransferase gene knockout mice. The Journal of nutritional biochemistry 20101001
Synergistic cytotoxic effects of arsenic trioxide plus dithiothreitol on mice oral cancer cells. Anticancer research 20100901
Identification of a coiled coil in werner syndrome protein that facilitates multimerization and promotes exonuclease processivity. The Journal of biological chemistry 20100813
The effect of desalivation on the malignant transformation of the tongue epithelium and associated stromal myofibroblasts in a rat 4-nitroquinoline 1-oxide-induced carcinogenesis model. International journal of experimental pathology 20100801
Proteomics-based identification of haptoglobin as a novel plasma biomarker in oral squamous cell carcinoma. Clinica chimica acta; international journal of clinical chemistry 20100704
Overcoming multidrug resistance in human cancer cells by natural compounds. Toxins 20100601
Dose-dependent changes in cyclin D1 in response to 4-nitroquinoline 1-oxide-induced DNA damage. Archives of biochemistry and biophysics 20100501
Rigid confocal endoscopy for in vivo imaging of experimental oral squamous intra-epithelial lesions. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20100401
Relationship between endoplasmic reticulum- and Golgi-associated calcium homeostasis and 4-NQO-induced DNA repair in Saccharomyces cerevisiae. Archives of microbiology 20100401
Wnt/beta-catenin signalling pathway following rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. Experimental and molecular pathology 20100201
Chemoprevention of oral cancer in animal models, and effect on leukoplakias in human patients with ZengShengPing, a mixture of medicinal herbs. Oral oncology 20100201
Enhancement of tongue carcinogenesis in Hras128 transgenic rats treated with 4-nitroquinoline 1-oxide. Oncology reports 20100201
The role of matrix metalloproteinases 2 and 9 during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. Journal of molecular histology 20100201
Co-treating with arecoline and 4-nitroquinoline 1-oxide to establish a mouse model mimicking oral tumorigenesis. Chemico-biological interactions 20100105
Transcriptional profiling reveals the expression of novel genes in response to various stimuli in the human dermatophyte Trichophyton rubrum. BMC microbiology 20100101
Capsaicin displays anti-proliferative activity against human small cell lung cancer in cell culture and nude mice models via the E2F pathway. PloS one 20100101
Apoptotic effects of chrysin in human cancer cell lines. International journal of molecular sciences 20100101
Decreased risk of squamous cell carcinoma of the head and neck in users of nonsteroidal anti-inflammatory drugs. International journal of otolaryngology 20100101
In vivo induction of phase II detoxifying enzymes, glutathione transferase and quinone reductase by citrus triterpenoids. BMC complementary and alternative medicine 20100101
Rrd1 isomerizes RNA polymerase II in response to rapamycin. BMC molecular biology 20100101
1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer. BMC cancer 20100101
Anticancer drugs from marine flora: an overview. Journal of oncology 20100101
Stromal myofibroblasts accompany modifications in the epithelial phenotype of tongue dysplastic and malignant lesions. Cancer microenvironment : official journal of the International Cancer Microenvironment Society 20091201
A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide. Cancer prevention research (Philadelphia, Pa.) 20091201
Loss of yeast peroxiredoxin Tsa1p induces genome instability through activation of the DNA damage checkpoint and elevation of dNTP levels. PLoS genetics 20091001
Global DNA hypomethylation suppresses squamous carcinogenesis in the tongue and esophagus. Cancer science 20090701
Overexpression of lecithin:retinol acyltransferase in the epithelial basal layer makes mice more sensitive to oral cavity carcinogenesis induced by a carcinogen. Cancer biology & therapy 20090701
Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma. Oncogene 20090625
Limonin methoxylation influences the induction of glutathione S-transferase and quinone reductase. Journal of agricultural and food chemistry 20090624
Animal models of cancer in the head and neck region. Clinical and experimental otorhinolaryngology 20090601
A mouse model for oral squamous cell carcinoma. Journal of molecular histology 20090601
ABT-510 is an effective chemopreventive agent in the mouse 4-nitroquinoline 1-oxide model of oral carcinogenesis. Cancer prevention research (Philadelphia, Pa.) 20090401
A novel immunocompetent murine model for Candida albicans-promoted oral epithelial dysplasia. Medical mycology 20090301
[Expression of survivin, Bcl-2 and p53 during 4-nitro-quinoline 1-oxide-induced rat tongue carcinogenesis]. Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20090301
No mutations found in exon 2 of gene p16CDKN2A during rat tongue carcinogenesis induced by 4-nitroquinoline-1-oxide. Journal of molecular histology 20090201
Citrus auraptene suppresses cyclin D1 and significantly delays N-methyl nitrosourea induced mammary carcinogenesis in female Sprague-Dawley rats. BMC cancer 20090101
Emerging role of Garcinol, the antioxidant chalcone from Garcinia indica Choisy and its synthetic analogs. Journal of hematology & oncology 20090101
Spontaneous regression of advanced hepatocellular carcinoma: a case report. Cases journal 20090101
Imbalance of tumor suppression genes expression following rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. In vivo (Athens, Greece) 20090101
Protective effects of solvent fractions of Mentha spicata (L.) leaves evaluated on 4-nitroquinoline-1-oxide induced chromosome damage and apoptosis in mouse bone marrow cells. Genetics and molecular biology 20090101
RecQ4 facilitates UV light-induced DNA damage repair through interaction with nucleotide excision repair factor xeroderma pigmentosum group A (XPA). The Journal of biological chemistry 20081024
Genomic instability in blood cells is able to predict the oral cancer risk: an experimental study in rats. Journal of molecular histology 20081001
Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice. Mutation research 20080926
Lack of promotion activity of diacylglycerol oil on 4-nitroquinoline 1-oxide induced carcinogenesis in the oral cavity of SD rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080901
Model of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromes. Clinical interventions in aging 20080901
Changes in expression of imprinted genes following treatment of human cancer cell lines with non-mutagenic or mutagenic carcinogens. International journal of oncology 20080801
Sensitivity of RECQL4-deficient fibroblasts from Rothmund-Thomson syndrome patients to genotoxic agents. Human genetics 20080701
Identification and dissection of a complex DNA repair sensitivity phenotype in Baker's yeast. PLoS genetics 20080701
In vitro assessment of clastogenicity of mobile-phone radiation (835 MHz) using the alkaline comet assay and chromosomal aberration test. Environmental toxicology 20080601
Identification and characterization of a Drosophila ortholog of WRN exonuclease that is required to maintain genome integrity. Aging cell 20080601
Antimutagenic activity of a novel ascorbic derivative, disodium isostearyl 2-O-L-ascorbyl phosphate. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080601
Suppressive effect of poly-gamma-glutamate on SOS response of Salmonella typhimurium induced by chemical mutagens. Journal of bioscience and bioengineering 20080601
Chemopreventive and therapeutic modulation of green tea polyphenols on drug metabolizing enzymes in 4-Nitroquinoline 1-oxide induced oral cancer. Chemico-biological interactions 20080415
A novel rasH2 mouse carcinogenesis model that is highly susceptible to 4-NQO-induced tongue and esophageal carcinogenesis is useful for preclinical chemoprevention studies. Carcinogenesis 20080201
Genetic analysis of the Neurospora crassa RAD14 homolog mus-43 and the RAD10 homolog mus-44 reveals that they belong to the mus-38 pathway of two nucleotide excision repair systems. Genes & genetic systems 20080201
Suppression of mutagens-induced SOS response by phytoncide solution using Salmonella typhimurium TA1535/pSK1002 umu test. Journal of oleo science 20080101
Characterization of a new rat model of head and neck squamous cell carcinoma. In vivo (Athens, Greece) 20080101
4NQO-induced rat tongue carcinoma: an ultrastructural study. Ultrastructural pathology 20080101
Anc1, a protein associated with multiple transcription complexes, is involved in postreplication repair pathway in S. cerevisiae. PloS one 20080101
Cortactin overexpression in the esophageal squamous cell carcinoma and its involvement in the carcinogenesis. Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20080101
Effects of heme oxygenase-1 inducer and inhibitor on experimental autoimmune uveoretinitis. Korean journal of ophthalmology : KJO 20071201
From old organisms to new molecules: integrative biology and therapeutic targets in accelerated human ageing. Cellular and molecular life sciences : CMLS 20071001
Placental glutathione S-transferase correlates with cellular proliferation during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20070901
Antigenotoxic effects of the phytoestrogen pelargonidin chloride and the polyphenol chlorogenic acid. Molecular nutrition & food research 20070701
Gingival changes in wistar rats after oral treatment with 4-nitroquinoline 1-oxide. European journal of dentistry 20070701
Possible enhancing activity of diacylglycerol on 4-nitroquinoline 1-oxide induced carcinogenesis of the tongue in human c-Ha-ras proto-oncogene transgenic rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070601
WRN functions in a RAD18-dependent damage avoidance pathway. Biological & pharmaceutical bulletin 20070601
Chemopreventive effect of fermented brown rice and rice bran on 4-nitroquinoline 1-oxide-induced oral carcinogenesis in rats. Oncology reports 20070401
A prostaglandin E2 receptor subtype EP1-selective antagonist, ONO-8711, suppresses 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. Carcinogenesis 20070301
Attenuation of 4-nitroquinoline 1-oxide induced in vitro lipid peroxidation by green tea polyphenols. Life sciences 20070227
Effects of sex hormones on rat tongue carcinoma induced by 4-nitroquinoline 1-oxide (4NQO). The Bulletin of Tokyo Dental College 20070201
Response of lymphocyte subsets and cytokines to Shenyang prescription in Sprague-Dawley rats with tongue squamous cell carcinomas induced by 4NQO. BMC cancer 20070101
QSAR of genotoxic active benzazoles. SAR and QSAR in environmental research 20070101
Diacylglycerol oil for the metabolic syndrome. Nutrition journal 20070101
Parp-1 deficiency does not increase the frequency of tumors in the oral cavity and esophagus of ICR/129Sv mice by 4-nitroquinoline 1-oxide, a carcinogen producing bulky adducts. Cancer letters 20060908
Chemopreventive efficacy of all-trans-retinoic acid in biodegradable microspheres against epithelial cancers: results in a 4-nitroquinoline 1-oxide-induced oral carcinogenesis model. International journal of pharmaceutics 20060831
Modulatory efficacy of green tea polyphenols on glycoconjugates and immunological markers in 4-Nitroquinoline 1-oxide-induced oral carcinogenesis-A therapeutic approach. Chemico-biological interactions 20060825
Selective loss of resistant alleles at p15INK4B and p16INK4A genes in chemically-induced rat tongue cancers. Oral oncology 20060801
Zinc deficiency potentiates induction and progression of lingual and esophageal tumors in p53-deficient mice. Carcinogenesis 20060701
4-Nitroquinoline 1-oxide forms 8-hydroxydeoxyguanosine in human fibroblasts through reactive oxygen species. Toxicological sciences : an official journal of the Society of Toxicology 20060601
An animal model for the rapid induction of tongue neoplasms in human c-Ha-ras proto-oncogene transgenic rats by 4-nitroquinoline 1-oxide: its potential use for preclinical chemoprevention studies. Carcinogenesis 20060301
Head and neck cancer cell lines exhibit differential mitochondrial repair deficiency in response to 4NQO. Oral oncology 20060201
A speed congenic rat strain bearing the tongue cancer susceptibility locus Tscc1 from Dark-Agouti rats. Cancer letters 20060118
Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress. BMC cancer 20060101
Expression of receptor for advanced glycation end products during rat tongue carcinogenesis by 4-nitroquinoline 1-oxide and effect of a selective cyclooxygenase-2 inhibitor, etodolac. Pathobiology : journal of immunopathology, molecular and cellular biology 20060101
Abnormal expression of bcl-2 and bax in rat tongue mucosa during the development of squamous cell carcinoma induced by 4-nitroquinoline 1-oxide. International journal of experimental pathology 20051201
Saccharomyces cerevisiae RAD53 (CHK2) but not CHK1 is required for double-strand break-initiated SCE and DNA damage-associated SCE after exposure to X rays and chemical agents. DNA repair 20051121
Genome-wide requirements for resistance to functionally distinct DNA-damaging agents. PLoS genetics 20050801
[Influence of 1.8 GHz microwave on DNA damage induced by 4 chemical mutagens]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20050601
Dietary garcinol inhibits 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in rats. Cancer letters 20050418
Dynamics of glutathione conjugation and conjugate efflux in detoxification of the carcinogen, 4-nitroquinoline 1-oxide: contributions of glutathione, glutathione S-transferase, and MRP1. Biochemistry 20050322
Dietary zinc modulation of COX-2 expression and lingual and esophageal carcinogenesis in rats. Journal of the National Cancer Institute 20050105
P-cadherin expression and survival rate in oral squamous cell carcinoma: an immunohistochemical study. BMC cancer 20050101
Multidrug resistance-associated protein 1 (MRP1) mediated vincristine resistance: effects of N-acetylcysteine and Buthionine sulfoximine. Cancer cell international 20050101
Genetic predisposition to 4NQO-induced tongue carcinogenesis in the rat. Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20050101
Suppressive effects of a selective cyclooxygenase-2 inhibitor, etodolac, on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20041201
Therapeutic efficacy of green tea polyphenols on cellular thiols in 4-Nitroquinoline 1-oxide-induced oral carcinogenesis. Chemico-biological interactions 20041015
Suppression of chemically induced and spontaneously occurring oxidative mutagenesis by three alleles of human OGG1 gene encoding 8-hydroxyguanine DNA glycosylase. Mutation research 20041004
Chlorhexidine induces DNA damage in rat peripheral leukocytes and oral mucosal cells. Journal of periodontal research 20041001
Genomic instability in non-neoplastic oral mucosa cells can predict risk during 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. Oral oncology 20041001
High frequency methylation of p16INK4A gene during 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. Oncology reports 20040701
The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function. DNA repair 20040603
Enhanced stimulation of chromosomal translocations by radiomimetic DNA damaging agents and camptothecin in Saccharomyces cerevisiae rad9 checkpoint mutants. Mutation research 20040322
Expressions of junB and c-fos are enhanced in 4-nitroquinoline 1-oxide-induced rat tongue cancers. Pathology international 20040101
Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice. Clinical cancer research : an official journal of the American Association for Cancer Research 20040101
p53 haploinsufficiency profoundly accelerates the onset of tongue tumors in mice lacking the xeroderma pigmentosum group A gene. The American journal of pathology 20031101
Antimutagenic activity of phenylpropanoids from clove (Syzygium aromaticum). Journal of agricultural and food chemistry 20031022
Changing expression of E- and P-cadherin during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20031001
Antimutagenic activity of flavonoids from Chrysanthemum morifolium. Bioscience, biotechnology, and biochemistry 20031001
Inhibitory effects of selective cyclooxygenase-2 inhibitors, nimesulide and etodolac, on the development of squamous cell dysplasias and carcinomas of the tongue in rats initiated with 4-nitroquinoline 1-oxide. Cancer letters 20030925
Correlation of P-cadherin and beta-catenin expression and phosphorylation with carcinogenesis in rat tongue cancer induced with 4-nitroquinoline 1-oxide. Oral oncology 20030701
Inhibitory effects of troglitazone, a peroxisome proliferator-activated receptor gamma ligand, in rat tongue carcinogenesis initiated with 4-nitroquinoline 1-oxide. Cancer science 20030401
Growth-inhibitory effects of the chemopreventive agent indole-3-carbinol are increased in combination with the polyamine putrescine in the SW480 colon tumour cell line. BMC cancer 20030101
A novel geranylated derivative, ethyl 3-(4'-geranyloxy-3'-methoxyphenyl)-2-propenoate, synthesized from ferulic acid suppresses carcinogenesis and inducible nitric oxide synthase in rat tongue. Oncology 20030101
[Erythroid differentiation of K562 cells resistant to 2-(4'-dimethylaminostyryl)quinoline 1-oxide or 4-nitroquinoline 1-oxide is significantly increased after thymidine treatment]. Izvestiia Akademii nauk. Seriia biologicheskaia 20030101
Dietary protocatechuic acid during the progression phase exerts chemopreventive effects on chemically induced rat tongue carcinogenesis. Asian Pacific journal of cancer prevention : APJCP 20030101
Distinction of carcinogens from mutagens by induction of liver cell foci in a model for detection of initiation activity. Cancer letters 20021215
Association of p16(INK4a) and pRb inactivation with immortalization of human cells. Carcinogenesis 20021201
Expression of beta-catenin in rat oral epithelial dysplasia induced by 4-nitroquinoline 1-oxide. Oral oncology 20021201
Chromosomal instability in B-lymphoblasotoid cell lines from Werner and Bloom syndrome patients. Mutation research 20020926
Genotoxicity is modulated by ascorbic acid. Studies using the wing spot test in Drosophila. Mutation research 20020926
Investigation of environmental factors for diagnosing malignant potential in oral epithelial dysplasia. Oral oncology 20020901
Modifying effects of dietary capsaicin and rotenone on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. Carcinogenesis 20020801
Insulin-like growth factor I induces MDM2-dependent degradation of p53 via the p38 MAPK pathway in response to DNA damage. The Journal of biological chemistry 20020503
Dietary silymarin suppresses 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in male F344 rats. Carcinogenesis 20020501
Werner and Bloom helicases are involved in DNA repair in a complementary fashion. Oncogene 20020131
Further evaluation of an in vivo micronucleus test on rat and mouse skin: results with five skin carcinogens. Mutation research 20020115
Different mutation status of the beta-catenin gene in carcinogen-induced colon, brain, and oral tumors in rats. Molecular carcinogenesis 20011201
Alteration of pRb expression in the development of rat tongue carcinoma induced by 4-nitroquinoline 1-oxide. Oral oncology 20011001
Butylhydroxytoluene (BHT) increases susceptibility of transgenic rasH2 mice to lung carcinogenesis. Journal of cancer research and clinical oncology 20011001
Antimutagenic activity of organosulfur compounds from Allium is associated with phase II enzyme induction. Mutation research 20010822
Suppression of chemical mutagen-induced SOS response by alkylphenols from clove (Syzygium aromaticum) in the Salmonella typhimurium TA1535/pSK1002 umu test. Journal of agricultural and food chemistry 20010801
Five quantitative trait loci affecting 4-nitroquinoline 1-oxide-induced tongue cancer in the rat. Japanese journal of cancer research : Gann 20010601
Prevention of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis by garlic. Fitoterapia 20010601
Xeroderma pigmentosum group A gene action as a protection factor against 4-nitroquinoline 1-oxide-induced tongue carcinogenesis. Carcinogenesis 20010401
Two-dimensional gel electrophoretic studies on the cellular aging: accumulation of alpha-2-macroglobulin in human fibroblasts with aging. Experimental gerontology 20010301
Effect of caffeine on the genotoxic effects of gamma radiation and 4-NQO in diploid yeast. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20010101
Inhibition of carcinogen induced c-Ha-ras and c-fos proto-oncogenes expression by dietary curcumin. BMC cancer 20010101
Properties