4,4'-((1H-1,2,4-triazol-1-yl)methylene)dibenzonitrile
Title | Journal |
---|---|
Evaluation of triclosan in the Hershberger and H295R steroidogenesis assays. | Toxicology letters 20180701 |
Inhibition of estrogen receptor reduces connexin 43 expression in breast cancers. | Toxicology and applied pharmacology 20180101 |
The promising effect of linagliptin and/or indole-3-carbinol on experimentally-induced polycystic ovarian syndrome. | Chemico-biological interactions 20170801 |
Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast Cancer. | The New England journal of medicine 20161103 |
Better Together: Targeted Combination Therapies in Breast Cancer. | Seminars in oncology 20151201 |
Enhancing Endocrine Therapy for Hormone Receptor-Positive Advanced Breast Cancer: Cotargeting Signaling Pathways. | Journal of the National Cancer Institute 20151001 |
Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. | Chemical research in toxicology 20150518 |
Palbociclib: first global approval. | Drugs 20150401 |
The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study. | The Lancet. Oncology 20150101 |
Anti-aromatase effect of resveratrol and melatonin on hormonal positive breast cancer cells co-cultured with breast adipose fibroblasts. | Toxicology in vitro : an international journal published in association with BIBRA 20141001 |
Testosterone ameliorates streptozotocin-induced memory impairment in male rats. | Acta pharmacologica Sinica 20140601 |
AroER tri-screen is a biologically relevant assay for endocrine disrupting chemicals modulating the activity of aromatase and/or the estrogen receptor. | Toxicological sciences : an official journal of the Society of Toxicology 20140501 |
Arsenic-induced cancer cell phenotype in human breast epithelia is estrogen receptor-independent but involves aromatase activation. | Archives of toxicology 20140201 |
Extra virgin olive oil potentiates the effects of aromatase inhibitors via glutathione depletion in estrogen receptor-positive human breast cancer (MCF-7) cells. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20131201 |
Identification of potent Yes1 kinase inhibitors using a library screening approach. | Bioorganic & medicinal chemistry letters 20130801 |
A pilot study on the use of a 7-day course of letrozole followed by misoprostol for the termination of early pregnancy up to 63 days. | Contraception 20121201 |
Zoledronic acid inhibits aromatase activity and phosphorylation: potential mechanism for additive zoledronic acid and letrozole drug interaction. | The Journal of steroid biochemistry and molecular biology 20121101 |
Macular oedema due to letrozole: a first case report. | Clinical & experimental optometry 20121101 |
New ruthenium(II)-letrozole complexes as anticancer therapeutics. | Journal of medicinal chemistry 20121025 |
Co-expression of estrogen receptor beta and aromatase in Japanese lung cancer patients: gender-dependent clinical outcome. | Life sciences 20121022 |
Novel aromatase inhibitors by structure-guided design. | Journal of medicinal chemistry 20121011 |
Effect of letrozole on uterine artery Doppler flow indices prior to first-trimester termination of pregnancy: a randomized controlled trial. | Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 20121001 |
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones. | Cancer letters 20121001 |
Effect of letrozole on uterine tonus and contractility: a randomized controlled trial. | Contraception 20121001 |
Does higher starting dose of FSH stimulation with letrozole improve fertility preservation outcomes in women with breast cancer? | Fertility and sterility 20121001 |
Discordant cellular response to presurgical letrozole in bilateral synchronous ER+ breast cancers with a KRAS mutation or FGFR1 gene amplification. | Molecular cancer therapeutics 20121001 |
Re: Effect of letrozole on uterine artery Doppler flow indices prior to first-trimester termination of pregnancy: a randomized controlled trial. V. C. Y. Lee, T. W. Y. Yeung, O. S. Tang, E. H. Y. Ng, W. S. B. Yeung and P. C. Ho. Ultrasound Obstet Gynecol 2012; 40: 392-397. | Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 20121001 |
Myocardial infarction due to coronary thrombus formation in a postmenopausal woman with breast cancer after initiation of letrozol therapy. | International journal of cardiology 20120920 |
Mechanistic links between oxidative/nitrosative stress and tumor necrosis factor alpha in letrozole-induced murine polycystic ovary: biochemical and pathological evidences for beneficial effect of pioglitazone. | Human & experimental toxicology 20120901 |
The development, application and limitations of breast cancer cell lines to study tamoxifen and aromatase inhibitor resistance. | The Journal of steroid biochemistry and molecular biology 20120901 |
Aromatase inhibitors and mood disturbances. | Palliative & supportive care 20120901 |
Effect of aromatase inhibitors on background parenchymal enhancement and amount of fibroglandular tissue at breast MR imaging. | Radiology 20120901 |
Suppression of plasma estrogen levels by letrozole and anastrozole is related to body mass index in patients with breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120820 |
Aromatase inhibition in obese women: how much is enough? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120820 |
Estrogen-regulated synaptogenesis in the hippocampus: sexual dimorphism in vivo but not in vitro. | The Journal of steroid biochemistry and molecular biology 20120801 |
Histological evaluation of rat larynx in experimental polycystic ovary syndrome model. | European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20120801 |
Bone effect of adjuvant tamoxifen, letrozole or letrozole plus zoledronic acid in early-stage breast cancer: the randomized phase 3 HOBOE study. | Annals of oncology : official journal of the European Society for Medical Oncology 20120801 |
Molecular mechanisms of a novel selenium-based complementary medicine which confers protection against hyperandrogenism-induced polycystic ovary. | Theriogenology 20120801 |
Sorafenib in locally advanced or metastatic breast cancer. | Expert opinion on investigational drugs 20120801 |
High fat-induced obesity associated with insulin-resistance increases FGF-2 content and causes stromal hyperplasia in rat ventral prostate. | Cell and tissue research 20120801 |
Reduced methadone clearance during aromatase inhibition. | Journal of clinical psychopharmacology 20120801 |
The pharmacokinetics of letrozole: association with key body mass metrics. | International journal of clinical pharmacology and therapeutics 20120801 |
Safe chemotherapy and hormone therapy for treating early breast cancer in a glucose 6-phosphate dehydrogenase-deficient patient: case report. | Anti-cancer drugs 20120801 |
Systematic review of lapatinib in combination with letrozole compared with other first-line treatments for hormone receptor positive(HR+) and HER2+ advanced or metastatic breast cancer(MBC). | Current medical research and opinion 20120801 |
Psychotropic medication during endocrine treatment for breast cancer. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20120701 |
Controlled ovarian hyperstimulation in women with polycystic ovarian syndrome with or without intrauterine insemination. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20120701 |
Aromatase inhibitor treatment of breast cancer cells increases the expression of let-7f, a microRNA targeting CYP19A1. | The Journal of pathology 20120701 |
In vitro evaluation of the interaction potential of irosustat with drug-metabolizing enzymes. | Drug metabolism and disposition: the biological fate of chemicals 20120701 |
Prognostic value of Bcl-2 in two independent populations of estrogen receptor positive breast cancer patients treated with adjuvant endocrine therapy. | Acta oncologica (Stockholm, Sweden) 20120701 |
Effect of letrozole on estradiol production and P450 aromatase messenger RNA expression of cultured luteinized granulosa cells from women with and without endometriosis. | Fertility and sterility 20120701 |
Changes in hormonal profile and seminal parameters with use of aromatase inhibitors in management of infertile men with low testosterone to estradiol ratios. | Fertility and sterility 20120701 |
Animal models of polycystic ovary syndrome: a focused review of rodent models in relationship to clinical phenotypes and cardiometabolic risk. | Fertility and sterility 20120701 |
Small-animal PET of steroid hormone receptors predicts tumor response to endocrine therapy using a preclinical model of breast cancer. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120701 |
AKT-aro and HER2-aro, models for de novo resistance to aromatase inhibitors; molecular characterization and inhibitor response studies. | Breast cancer research and treatment 20120701 |
Whole-genome analysis informs breast cancer response to aromatase inhibition. | Nature 20120621 |
AIB1:ERα transcriptional activity is selectively enhanced in aromatase inhibitor-resistant breast cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120615 |
Aromatase inhibition abolishes LTP generation in female but not in male mice. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120613 |
Bone mineral density in breast cancer patients treated with adjuvant letrozole, tamoxifen, or sequences of letrozole and tamoxifen in the BIG 1-98 study (SAKK 21/07). | Annals of oncology : official journal of the European Society for Medical Oncology 20120601 |
Efficacy of zoledronic acid in postmenopausal Japanese women with early breast cancer receiving adjuvant letrozole: 12-month results. | Breast cancer research and treatment 20120601 |
Polymorphisms of CYP19A1 and response to aromatase inhibitors in metastatic breast cancer patients. | Breast cancer research and treatment 20120601 |
Does hormonal therapy have a therapeutic role in metastatic primary small cell neuroendocrine breast carcinoma? Case report and literature review. | Clinical breast cancer 20120601 |
The effects of letrozole on ovarian stimulation for fertility preservation in cancer-affected women. | Reproductive biomedicine online 20120601 |
Evaluation of anticancer drug-loaded nanoparticle characteristics by nondestructive methodologies. | AAPS PharmSciTech 20120601 |
Pharmacogenomics of third-generation aromatase inhibitors. | Expert opinion on pharmacotherapy 20120601 |
Comparison of the effects of letrozole and clomiphene citrate for ovulation induction in infertile women with polycystic ovary syndrome. | Minerva ginecologica 20120601 |
Short-term and low-dose prednisolone administration reduces aromatase inhibitor-induced arthralgia in patients with breast cancer. | Anticancer research 20120601 |
[A case of elderly locally-advanced breast cancer with skin ulcer responding to letrozole]. | Gan to kagaku ryoho. Cancer & chemotherapy 20120601 |
L-BLP25 vaccine plus letrozole induces a TH1 immune response and has additive antitumor activity in MUC1-expressing mammary tumors in mice. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120515 |
Subjective cognitive complaints one year after ceasing adjuvant endocrine treatment for early-stage breast cancer. | British journal of cancer 20120508 |
Prognostic and predictive role of ESR1 status for postmenopausal patients with endocrine-responsive early breast cancer in the Danish cohort of the BIG 1-98 trial. | Annals of oncology : official journal of the European Society for Medical Oncology 20120501 |
Complementary and alternative medicines use by Scottish women with breast cancer. What, why and the potential for drug interactions? | European journal of clinical pharmacology 20120501 |
The Pregnancy in Polycystic Ovary Syndrome II (PPCOS II) trial: rationale and design of a double-blind randomized trial of clomiphene citrate and letrozole for the treatment of infertility in women with polycystic ovary syndrome. | Contemporary clinical trials 20120501 |
Circulating antimüllerian hormone levels in boys decline during early puberty and correlate with inhibin B. | Fertility and sterility 20120501 |
What is the optimal follicular size before triggering ovulation in intrauterine insemination cycles with clomiphene citrate or letrozole? An analysis of 988 cycles. | Fertility and sterility 20120501 |
The efficacy and safety of neoadjuvant chemotherapy +/- letrozole in postmenopausal women with locally advanced breast cancer: a randomized phase III clinical trial. | Breast cancer research and treatment 20120401 |
Hormone treatment without surgery for patients aged 75 years or older with operable breast cancer. | Annals of surgical oncology 20120401 |
Ki-67: level of evidence and methodological considerations for its role in the clinical management of breast cancer: analytical and critical review. | Breast cancer research and treatment 20120401 |
17β-Estradiol regulates cyclin A1 and cyclin B1 gene expression in adult rat seminiferous tubules. | Journal of molecular endocrinology 20120401 |
Primary breast cancer of the vulva: a case report. | Journal of lower genital tract disease 20120401 |
Aromatase inhibitors or gonadotropin-releasing hormone agonists for the management of uterine adenomyosis: a randomized controlled trial. | Acta obstetricia et gynecologica Scandinavica 20120401 |
The effect of acute aromatase inhibition on breast parenchymal enhancement in magnetic resonance imaging: a prospective pilot clinical trial. | Menopause (New York, N.Y.) 20120401 |
Simultaneous quantitative analysis of letrozole, its carbinol metabolite, and carbinol glucuronide in human plasma by LC-MS/MS. | Analytical and bioanalytical chemistry 20120401 |
Stimulation of Sertoli cell proliferation: defining the response interval to an inhibitor of estrogen synthesis in the boar. | Reproduction (Cambridge, England) 20120401 |
Optimization of the aromatase inhibitory activities of pyridylthiazole analogues of resveratrol. | Bioorganic & medicinal chemistry 20120401 |
A pilot study of letrozole for one year in women at enhanced risk of developing breast cancer: effects on mammographic density. | Anticancer research 20120401 |
CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the breast international group 1-98 trial. | Journal of the National Cancer Institute 20120321 |
CYP2D6 genotype as a marker for benefit of adjuvant tamoxifen in postmenopausal women: lessons learned. | Journal of the National Cancer Institute 20120321 |
Predictors of aromatase inhibitor discontinuation as a result of treatment-emergent symptoms in early-stage breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120320 |
Insight into the binding interactions of CYP450 aromatase inhibitors with their target enzyme: a combined molecular docking and molecular dynamics study. | Journal of molecular modeling 20120301 |
Comparison of efficacy of letrozole and clomiphene citrate in ovulation induction in Indian women with polycystic ovarian syndrome. | Archives of gynecology and obstetrics 20120301 |
Final 5-year results of Z-FAST trial: adjuvant zoledronic acid maintains bone mass in postmenopausal breast cancer patients receiving letrozole. | Cancer 20120301 |
Longer-term outcomes of letrozole versus placebo after 5 years of tamoxifen in the NCIC CTG MA.17 trial: analyses adjusting for treatment crossover. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120301 |
Uptake of a randomized breast cancer prevention trial comparing letrozole to placebo in BRCA1/2 mutations carriers: the LIBER trial. | Familial cancer 20120301 |
Randomized comparison of superovulation with letrozole vs. clomiphene citrate in an IUI program for women with recently surgically treated minimal to mild endometriosis. | Acta obstetricia et gynecologica Scandinavica 20120301 |
Endometrial receptivity defects during IVF cycles with and without letrozole. | Human reproduction (Oxford, England) 20120301 |
Deep time: the long and the short of adjuvant endocrine therapy for breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120301 |
New aromatase inhibitors from the 3-pyridyl arylether and 1-aryl pyrrolo[2,3-c]pyridine series. | Bioorganic & medicinal chemistry letters 20120301 |
Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer. | The New England journal of medicine 20120209 |
Sequential changes in gene expression profiles in breast cancers during treatment with the aromatase inhibitor, letrozole. | The pharmacogenomics journal 20120201 |
Pharmacotherapy of polycystic ovary syndrome--an update. | Fundamental & clinical pharmacology 20120201 |
Higher efficacy of letrozole in combination with trastuzumab compared to letrozole monotherapy as first-line treatment in patients with HER2-positive, hormone-receptor-positive metastatic breast cancer - results of the eLEcTRA trial. | Breast (Edinburgh, Scotland) 20120201 |
Bone health in a prospective cohort of postmenopausal women receiving aromatase inhibitors for early breast cancer. | Breast (Edinburgh, Scotland) 20120201 |
Choroidal and optic disc metastases from breast cancer and their response to combination pharmacotherapy with tamoxifen, cyclophosphamide hydrate, letrozole, and bevacizumab. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20120201 |
Immediate Administration of Zoledronic Acid Reduces Aromatase Inhibitor-Associated Bone Loss in Postmenopausal Women With Early Breast Cancer: 12-month analysis of the E-ZO-FAST trial. | Clinical breast cancer 20120201 |
Diagnosis and management of precocious puberty in atypical presentations of McCune-Albright syndrome: a case series review. | Journal of pediatric and adolescent gynecology 20120201 |
Antitumor activity of chemoendocrine therapy in premenopausal and postmenopausal models with human breast cancer xenografts. | Oncology reports 20120201 |
Severe ovarian hyperstimulation syndrome after letrozole-gonadotropin stimulation: a case report. | Journal of assisted reproduction and genetics 20120201 |
Opposing effects of Runx2 and estradiol on breast cancer cell proliferation: in vitro identification of reciprocally regulated gene signature related to clinical letrozole responsiveness. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120201 |
High non-compliance in the use of letrozole after 2.5 years of extended adjuvant endocrine therapy. Results from the IDEAL randomized trial. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20120201 |
Aromatase activity after a short-course of letrozole administration in adult men at sea level and at high altitude (with or without excessive erythrocytosis). | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20120201 |
Phase II trial with letrozole to maximum response as primary systemic therapy in postmenopausal patients with ER/PgR[+] operable breast cancer. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20120201 |
[A case of liver metastasis of breast cancer responding to letrozole]. | Gan to kagaku ryoho. Cancer & chemotherapy 20120201 |
A case of pituitary metastasis from breast cancer that presented as left visual disturbance. | Journal of Korean Neurosurgical Society 20120201 |
Metastatic progression with resistance to aromatase inhibitors is driven by the steroid receptor coactivator SRC-1. | Cancer research 20120115 |
Beyond trastuzumab: novel therapeutic strategies in HER2-positive metastatic breast cancer. | British journal of cancer 20120103 |
The advantage of letrozole over tamoxifen in the BIG 1-98 trial is consistent in younger postmenopausal women and in those with chemotherapy-induced menopause. | Breast cancer research and treatment 20120101 |
Adherence to adjuvant therapy in post-menopausal breast cancer patients: a review. | European journal of cancer care 20120101 |
Effect of androgen treatment during foetal and/or neonatal life on ovarian function in prepubertal and adult rats. | Reproduction (Cambridge, England) 20120101 |
The carcinoembryonic antigen as a potential prognostic marker for neuroendocrine carcinoma of the breast. | Anticancer research 20120101 |
Collision of three histologically distinct endometrial cancers of the uterus. | Journal of Korean medical science 20120101 |
Multiple approaches for individualized fertility protective therapy in cancer patients. | Obstetrics and gynecology international 20120101 |
Impact of the introduction of government use licenses on the drug expenditure on seven medicines in Thailand. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20120101 |
Comparison of treatment outcomes of infertile women by clomiphene citrate and letrozole with gonadotropins underwent intrauterine insemination. | Acta medica Iranica 20120101 |
Trace glucose and lipid metabolism in high androgen and high-fat diet induced polycystic ovary syndrome rats. | Reproductive biology and endocrinology : RB&E 20120101 |
Modularity in protein complex and drug interactions reveals new polypharmacological properties. | PloS one 20120101 |
Oocyte cryostorage to preserve fertility in oncological patients. | Obstetrics and gynecology international 20120101 |
Dosage optimization for letrozole treatment in clomiphene-resistant patients with polycystic ovary syndrome: a prospective interventional study. | Obstetrics and gynecology international 20120101 |
Role of estrogen receptor signaling in breast cancer metastasis. | International journal of breast cancer 20120101 |
Bromodomain-Containing Protein 4: A Dynamic Regulator of Breast Cancer Metastasis through Modulation of the Extracellular Matrix. | International journal of breast cancer 20120101 |
Enhanced secondary analysis of survival data: reconstructing the data from published Kaplan-Meier survival curves. | BMC medical research methodology 20120101 |
The use of androgens or androgen-modulating agents in poor responders undergoing in vitro fertilization: a systematic review and meta-analysis. | Human reproduction update 20120101 |
Outcome of metformin treatment in polycystic ovary syndrome. | Mymensingh medical journal : MMJ 20120101 |
Relationships between serum HER2 ECD, TIMP-1 and clinical outcomes in Taiwanese breast cancer. | World journal of surgical oncology 20120101 |
Aromatase inhibitors for PCOS: a systematic review and meta-analysis. | Human reproduction update 20120101 |
Efficacy and tolerability of lapatinib in the management of breast cancer. | Breast cancer : basic and clinical research 20120101 |
High-fat diet obesity associated with insulin resistance increases cell proliferation, estrogen receptor, and PI3K proteins in rat ventral prostate. | Journal of andrology 20120101 |
Fertility preservation in female cancer patients. | ISRN obstetrics and gynecology 20120101 |
The Effect of Cold Ischemia Time and/or Formalin Fixation on Estrogen Receptor, Progesterone Receptor, and Human Epidermal Growth Factor Receptor-2 Results in Breast Carcinoma. | Pathology research international 20120101 |
Membrane progesterone receptor alpha as a potential prognostic biomarker for breast cancer survival: a retrospective study. | PloS one 20120101 |
Potential role of aromatase over estrogen receptor gene polymorphisms in migraine susceptibility: a case control study from North India. | PloS one 20120101 |
Aloe barbadensis Mill. formulation restores lipid profile to normal in a letrozole-induced polycystic ovarian syndrome rat model. | Pharmacognosy research 20120101 |
Trastuzumab for HER2-Positive Metastatic Breast Cancer: Clinical and Economic Considerations. | Clinical Medicine Insights. Oncology 20120101 |
Innovative oral treatments of uterine leiomyoma. | Obstetrics and gynecology international 20120101 |
Infertility. | Obstetrics and gynecology international 20120101 |
Cancer, fertility preservation, and future pregnancy: a comprehensive review. | Obstetrics and gynecology international 20120101 |
Effects of a non-steroidal aromatase inhibitor on ovarian function in cattle. | Reproduction, fertility, and development 20120101 |
Bilateral de quervain syndrome after aromatase inhibitor administration: a case report and review of the literature. | Case reports in medicine 20120101 |
Managing arthralgia in a postmenopausal woman taking an aromatase inhibitor for hormonesensitive early breast cancer: a case study. | Cancer management and research 20120101 |
Global microRNA expression profiling of high-risk ER+ breast cancers from patients receiving adjuvant tamoxifen mono-therapy: a DBCG study. | PloS one 20120101 |
McCune-Albright syndrome and the extraskeletal manifestations of fibrous dysplasia. | Orphanet journal of rare diseases 20120101 |
Bioactive dietary supplements reactivate ER expression in ER-negative breast cancer cells by active chromatin modifications. | PloS one 20120101 |
Trastuzumab-induced myocardiotoxicity mimicking acute coronary syndrome. | Case reports in oncology 20120101 |
Postmenopausal women with DCIS post-mastectomy: a potential role for aromatase inhibitors. | The breast journal 20120101 |
[Will targeted therapies replace chemotherapy?]. | Revue medicale de Liege 20120101 |
Identification and characterization of nucleolin as a COUP-TFII coactivator of retinoic acid receptor β transcription in breast cancer cells. | PloS one 20120101 |
TIMP-1 induces an EMT-like phenotypic conversion in MDCK cells independent of its MMP-inhibitory domain. | PloS one 20120101 |
A prospective randomized trial comparing the efficacy of Letrozole and Clomiphene citrate in induction of ovulation in polycystic ovarian syndrome. | Journal of human reproductive sciences 20120101 |
Radiation induced esophageal adenocarcinoma in a woman previously treated for breast cancer and renal cell carcinoma. | BMC research notes 20120101 |
Marked increase of final height by long-term aromatase inhibition in a boy with idiopathic short stature. | Journal of pediatric endocrinology & metabolism : JPEM 20120101 |
Severe toxicity with a generic formulation of zoledronic Acid: a case report. | Clinical medicine insights. Case reports 20120101 |
Dual IGF-1R/InsR inhibitor BMS-754807 synergizes with hormonal agents in treatment of estrogen-dependent breast cancer. | Cancer research 20111215 |
Design and synthesis of novel human epidermal growth factor receptor 2 (HER2)/epidermal growth factor receptor (EGFR) dual inhibitors bearing a pyrrolo[3,2-d]pyrimidine scaffold. | Journal of medicinal chemistry 20111208 |
Early operable breast cancer in elderly women treated with an aromatase inhibitor letrozole as sole therapy. | British journal of cancer 20111206 |
Extended high dose letrozole regimen versus short low dose letrozole regimen as an adjuvant to gonadotropin releasing hormone antagonist protocol in poor responders undergoing IVF-ET. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20111201 |
The effects of metformin and letrozole on endometrium and ovary in a rat model. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20111201 |
Identifying potential adverse effects using the web: a new approach to medical hypothesis generation. | Journal of biomedical informatics 20111201 |
Invasive lobular carcinoma: response to neoadjuvant letrozole therapy. | Breast cancer research and treatment 20111201 |
[Lymphangioleiomyomatosis: new therapeutic approaches]. | Archivos de bronconeumologia 20111201 |
Progress in endocrine approaches to the treatment and prevention of breast cancer. | Maturitas 20111201 |
Low residual proliferation after short-term letrozole therapy is an early predictive marker of response in high proliferative ER-positive breast cancer. | Endocrine-related cancer 20111201 |
Quality-adjusted survival analysis of first-line treatment of hormone-receptor-positive HER2+ metastatic breast cancer with letrozole alone or in combination with lapatinib. | Current medical research and opinion 20111201 |
Use of the aromatase inhibitor letrozole for ovulation induction in women with polycystic ovarian syndrome. | Clinical obstetrics and gynecology 20111201 |
The EORTC 10041/BIG 03-04 MINDACT trial is feasible: results of the pilot phase. | European journal of cancer (Oxford, England : 1990) 20111201 |
An overview of letrozole in postmenopausal women with hormone-responsive breast cancer. | Advances in therapy 20111201 |
[Role of medical treatment for symptomatic leiomyoma management in premenopausal women]. | Journal de gynecologie, obstetrique et biologie de la reproduction 20111201 |
Putting the cardiovascular safety of aromatase inhibitors in patients with early breast cancer into perspective: a systematic review of the literature. | Drug safety 20111201 |
A prospective double-blinded, randomized, placebo-controlled trial on the use of letrozole pretreatment with misoprostol for second-trimester medical abortion. | Contraception 20111201 |
Approval summary: letrozole (Femara® tablets) for adjuvant and extended adjuvant postmenopausal breast cancer treatment: conversion of accelerated to full approval. | The oncologist 20111201 |
[A case of an elderly breast cancer patient achieving partial response with toremifene without efficacy of letrozole as a preoperative primary endocrine therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20111201 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
Diverse animal models to examine potential role(s) and mechanism of endocrine disrupting chemicals on the tumor progression and prevention: Do they have tumorigenic or anti-tumorigenic property? | Laboratory animal research 20111201 |
NCI's provocative questions on cancer: some answers to ignite discussion. | Oncotarget 20111201 |
High yield of oocytes without an increase in circulating estradiol levels in breast cancer patients treated with follicle-stimulating hormone and aromatase inhibitor in standard gonadotropin-releasing hormone analogue protocols. | The Israel Medical Association journal : IMAJ 20111201 |
Significance of ER-Src axis in hormonal therapy resistance. | Breast cancer research and treatment 20111101 |
Single nucleotide polymorphisms of CYP19A1 predict clinical outcomes and adverse events associated with letrozole in patients with metastatic breast cancer. | Cancer chemotherapy and pharmacology 20111101 |
Androgens and musculoskeletal symptoms among breast cancer patients on aromatase inhibitor therapy. | Breast cancer research and treatment 20111101 |
Preliminary study of letrozole use for improving spermatogenesis in non-obstructive azoospermia patients with normal serum FSH. | Asian journal of andrology 20111101 |
Estimating rates of multiple gestation pregnancies: sample size calculation from the assessment of multiple intrauterine gestations from ovarian stimulation (AMIGOS) trial. | Contemporary clinical trials 20111101 |
Body mass index-associated differences in response to ovulation induction with letrozole. | Fertility and sterility 20111101 |
Randomized phase II trial of letrozole plus anti-MUC1 antibody AS1402 in hormone receptor-positive locally advanced or metastatic breast cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111101 |
Activation of the mTOR pathway by low levels of xenoestrogens in breast epithelial cells from high-risk women. | Carcinogenesis 20111101 |
Plasma letrozole concentrations in postmenopausal women with breast cancer are associated with CYP2A6 genetic variants, body mass index, and age. | Clinical pharmacology and therapeutics 20111101 |
Does the addition of clomiphene citrate or letrazole to gonadotropin treatment enhance the oocyte yield in poor responders undergoing IVF? | Journal of assisted reproduction and genetics 20111101 |
Assessment of letrozole and tamoxifen alone and in sequence for postmenopausal women with steroid hormone receptor-positive breast cancer: the BIG 1-98 randomised clinical trial at 8·1 years median follow-up. | The Lancet. Oncology 20111101 |
[Long-term follow-up study: indolemamine 2,3-dioxygenase activity during chemotherapy or hormone therapy in patients with breast cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20111101 |
[A case of scalp metastases from breast cancer successfully treated with letrozole]. | Gan to kagaku ryoho. Cancer & chemotherapy 20111101 |
4-({(E)-[2-(But-3-en-1-yl)-1-(prop-2-en-1-yl)-4-sulfanyl-1H-imidazol-5-yl]methyl-idene}amino)-3-phenyl-1H-1,2,4-triazole-5(4H)-thione. | Acta crystallographica. Section E, Structure reports online 20111101 |
[Determination of 6 antiestrogens in fish tissues by ultra performance liquid chromatography-tandem mass spectrometry]. | Se pu = Chinese journal of chromatography 20111101 |
Drugs for ovulation induction. | The Medical letter on drugs and therapeutics 20111031 |
Aromatase inhibitors in pediatrics. | Nature reviews. Endocrinology 20111025 |
Early metabolic response to neoadjuvant letrozole, measured by FDG PET/CT, is correlated with a decrease in the Ki67 labeling index in patients with hormone receptor-positive primary breast cancer: a pilot study. | Breast cancer (Tokyo, Japan) 20111001 |
Which patients benefit most from adjuvant aromatase inhibitors? Results using a composite measure of prognostic risk in the BIG 1-98 randomized trial. | Annals of oncology : official journal of the European Society for Medical Oncology 20111001 |
Population pharmacokinetic analysis of letrozole in Japanese postmenopausal women. | European journal of clinical pharmacology 20111001 |
Effective role of hormonal therapy in metastatic primary neuroendocrine breast carcinoma. | Clinical breast cancer 20111001 |
A randomized trial of ovulation induction with two different doses of Letrozole in women with PCOS. | Archives of gynecology and obstetrics 20111001 |
Breast cancer medications and vision: effects of treatments for early-stage disease. | Current eye research 20111001 |
Clomiphene citrate versus letrozole: molecular analysis of the endometrium in women with polycystic ovary syndrome. | Fertility and sterility 20111001 |
Aromatase inhibition for refractory endometriosis-related chronic pelvic pain. | Fertility and sterility 20111001 |
Metaplastic breast carcinoma: a case report and systematic review of the literature. | Pathology international 20111001 |
Transcriptional responses in Japanese medaka (Oryzias latipes) exposed to binary mixtures of an estrogen and anti-estrogens. | Aquatic toxicology (Amsterdam, Netherlands) 20111001 |
Strategies for maximizing growth in puberty in children with short stature. | Pediatric clinics of North America 20111001 |
Is there a case for anti-HER2 therapy without chemotherapy in early breast cancer? | Breast (Edinburgh, Scotland) 20111001 |
Neural 17β-estradiol facilitates long-term potentiation in the hippocampal CA1 region. | Neuroscience 20110929 |
Clinical and economic benefits of aromatase inhibitor therapy in early-stage breast cancer. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110915 |
Synthesis and structure-activity relationship of 1- and 2-substituted-1,2,3-triazole letrozole-based analogues as aromatase inhibitors. | European journal of medicinal chemistry 20110901 |
Sequential use of letrozole and gonadotrophin in women with poor ovarian reserve: a randomized controlled trial. | Reproductive biomedicine online 20110901 |
Post-marketing safety evaluation of S-1 in patients with inoperable or recurrent breast cancer: especially in patients treated with S-1 + trastuzumab. | Japanese journal of clinical oncology 20110901 |
Management of patients with metastatic breast cancer. | Advances in therapy 20110901 |
Initialization of adjuvant hormonal treatment for breast cancer. | Advances in therapy 20110901 |
[Letrozole vs. tamoxifen as neoadjuvant therapy for postmenopausal patients with hormone-dependent locally-advanced breast cancer]. | Ginecologia y obstetricia de Mexico 20110901 |
Contemporary issues in precocious puberty. | Indian journal of endocrinology and metabolism 20110901 |
Growth hormone in the management of female infertility. | Indian journal of endocrinology and metabolism 20110901 |
3-(4-Nitro-phen-yl)-1H-1,2,4-triazole-5(4H)-thione. | Acta crystallographica. Section E, Structure reports online 20110901 |
An effect of letrozole on gastric cancer? | Journal of gastric cancer 20110901 |
Comparison of mild ovarian stimulation with conventional ovarian stimulation in poor responders. | Clinical and experimental reproductive medicine 20110901 |
Aromatase inhibitor-induced loss of grip strength is body mass index dependent: hypothesis-generating findings for its pathogenesis. | Annals of oncology : official journal of the European Society for Medical Oncology 20110801 |
Fertility preservation in women--a practical guide to preservation techniques and therapeutic strategies in breast cancer, Hodgkin's lymphoma and borderline ovarian tumours by the fertility preservation network FertiPROTEKT. | Archives of gynecology and obstetrics 20110801 |
The levels of nitric oxide and asymmetric dimethylarginine in the rat endometriosis model. | The journal of obstetrics and gynaecology research 20110801 |
Letrozole withdrawal response in locally advanced breast cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20110801 |
Estrogenic regulation of dopaminergic neurons in the opportunistically breeding zebra finch. | General and comparative endocrinology 20110801 |
Aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole and vorozole templates. | ChemMedChem 20110801 |
Killing the second messenger: targeting loss of cell cycle control in endocrine-resistant breast cancer. | Endocrine-related cancer 20110801 |
A bovine model for examining the effects of an aromatase inhibitor on ovarian function in women. | Fertility and sterility 20110801 |
Strategies for subtypes--dealing with the diversity of breast cancer: highlights of the St. Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011. | Annals of oncology : official journal of the European Society for Medical Oncology 20110801 |
Inhibition of oestrogen biosynthesis induces mild anxiety in C57BL/6J ovariectomized female mice. | Neuroscience bulletin 20110801 |
An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype. | PLoS genetics 20110801 |
Current role and safety profile of aromatase inhibitors in early breast cancer. | Expert review of anticancer therapy 20110801 |
Autophagy and endocrine resistance in breast cancer. | Expert review of anticancer therapy 20110801 |
Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2. | Journal of medicinal chemistry 20110714 |
Adaptive changes results in activation of alternate signaling pathways and resistance to aromatase inhibitor resistance. | Molecular and cellular endocrinology 20110704 |
Molecular effects of oestrogen deprivation in breast cancer. | Molecular and cellular endocrinology 20110704 |
A comparison of the effect of short-term aromatase inhibitor (letrozole) and GnRH agonist (triptorelin) versus case control on pregnancy rate and symptom and sign recurrence after laparoscopic treatment of endometriosis. | Archives of gynecology and obstetrics 20110701 |
Overview of adjuvant trials of aromatase inhibitors in early breast cancer. | Steroids 20110701 |
Binding features of steroidal and nonsteroidal inhibitors. | Steroids 20110701 |
Aromatase inhibitors and xenograft studies. | Steroids 20110701 |
Estrogen receptor-β activation in combination with letrozole blocks the growth of breast cancer tumors resistant to letrozole therapy. | Steroids 20110701 |
Meta-analysis of letrozole versus clomiphene citrate in polycystic ovary syndrome. | Reproductive biomedicine online 20110701 |
Trastuzumab and pertuzumab produce changes in morphology and estrogen receptor signaling in ovarian cancer xenografts revealing new treatment strategies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110701 |
Anti-Mullerian hormone and antral follicle count as predictors for embryo/oocyte cryopreservation cycle outcomes in breast cancer patients stimulated with letrozole and follicle stimulating hormone. | Journal of assisted reproduction and genetics 20110701 |
Use of letrozole challenge test to adjust gonadotropin dose in non-down-regulated cycles. | Fertility and sterility 20110630 |
Letrozole and gonadotropins versus luteal estradiol and GnRH-antagonist protocol: additional concerns. | Fertility and sterility 20110630 |
Discussion on letrozole-Gn-antagonist group needing an early start of antagonist. | Fertility and sterility 20110630 |
Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: clinical and biomarker outcomes and predictive value of the baseline PAM50-based intrinsic subtype--ACOSOG Z1031. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110610 |
A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer. | British journal of cancer 20110607 |
A Q-TWiST analysis comparing panitumumab plus best supportive care (BSC) with BSC alone in patients with wild-type KRAS metastatic colorectal cancer. | British journal of cancer 20110607 |
PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer. | Oncogene 20110602 |
The efficacy of HER2-targeted agents in metastatic breast cancer: a meta-analysis. | Annals of oncology : official journal of the European Society for Medical Oncology 20110601 |
An 'omics' approach to determine the mechanisms of acquired aromatase inhibitor resistance. | Omics : a journal of integrative biology 20110601 |
When to start an aromatase inhibitor: now or later? | Journal of surgical oncology 20110601 |
Complete response in HER2+ leptomeningeal carcinomatosis from breast cancer with intrathecal trastuzumab. | Breast cancer research and treatment 20110601 |
Synthesis and in vitro studies of biodegradable thiolated chitosan hydrogels for breast cancer therapy. | International journal of biological macromolecules 20110601 |
Reproductive outcome after letrozole versus laparoscopic ovarian drilling for clomiphene-resistant polycystic ovary syndrome. | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20110601 |
Effect of androgen supplementation or modulation on ovarian stimulation outcome in poor responders: a meta-analysis. | Reproductive biomedicine online 20110601 |
Lead optimization of 4-imidazolylflavans: new promising aromatase inhibitors. | European journal of medicinal chemistry 20110601 |
Letrozole and gonadotropins versus luteal estradiol and gonadotropin-releasing hormone antagonist protocol in women with a prior low response to ovarian stimulation. | Fertility and sterility 20110601 |
Inhibitory effects of calcitriol on the growth of MCF-7 breast cancer xenografts in nude mice: selective modulation of aromatase expression in vivo. | Hormones & cancer 20110601 |
Implications of bone-only metastases in breast cancer: favorable preference with excellent outcomes of hormone receptor positive breast cancer. | Cancer research and treatment : official journal of Korean Cancer Association 20110601 |
Benign metastasizing leiomyoma with multiple lymph node metastasis: a case report. | Cancer research and treatment : official journal of Korean Cancer Association 20110601 |
Efficacy of fulvestrant in heavily pretreated postmenopausal women with advanced breast cancer: a preliminary report. | Journal of breast cancer 20110601 |
Use of tamoxifen and aromatase inhibitors in a large population-based cohort of women with breast cancer. | British journal of cancer 20110510 |
Aromatase inhibitors in the treatment of bladder endometriosis. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20110501 |
Assessing the efficacy of targeted therapy using circulating epithelial tumor cells (CETC): the example of SERM therapy monitoring as a unique tool to individualize therapy. | Journal of cancer research and clinical oncology 20110501 |
Bone metabolism and quality-of-life of postmenopausal women with invasive breast cancer receiving neoadjuvant hormonal therapy: sub-analyses from celecoxib anti-aromatase neoadjuvant (CAAN) trial. | The Journal of steroid biochemistry and molecular biology 20110501 |
Transcriptional responses in the brain, liver and gonad of Japanese ricefish (Oryzias latipes) exposed to two anti-estrogens. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20110501 |
Random-start controlled ovarian hyperstimulation for emergency fertility preservation in letrozole cycles. | Fertility and sterility 20110501 |
Aromatase inhibition causes increased amplitude, but not frequency, of hypothalamic-pituitary output in normal women. | Fertility and sterility 20110501 |
Aromatase inhibition: a potential target for the management of recurrent or metastatic endometrial cancer by letrozole: more questions than answers? | Expert opinion on investigational drugs 20110501 |
Drug safety evaluation of exemestane. | Expert opinion on drug safety 20110501 |
Medical oncology: Letrozole efficacy confirmed. | Nature reviews. Clinical oncology 20110501 |
Aromatase inhibitors for ovulation induction and ovarian stimulation. | Clinical endocrinology 20110501 |
Aromatase inhibitor-induced skin adverse reactions: exemestane-related cutaneous vasculitis. | Journal of the European Academy of Dermatology and Venereology : JEADV 20110501 |
7-(4-Chloro-benzyl-idene)-3-[(4-chloro-phen-oxy)meth-yl]-6-(4-nitro-thio-phen-2-yl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thia-diazine. | Acta crystallographica. Section E, Structure reports online 20110501 |
Hyaluronic acid-bound letrozole nanoparticles restore sensitivity to letrozole-resistant xenograft tumors in mice. | Journal of nanoscience and nanotechnology 20110501 |
Is primary endocrine therapy effective in treating the elderly, unfit patient with breast cancer? | Annals of the Royal College of Surgeons of England 20110501 |
Analysis of mTOR inhibition-involved pathway in ovarian clear cell adenocarcinoma. | Acta histochemica et cytochemica 20110428 |
Letrozole induces hepatotoxicity without causing oxidative stress: the protective effect of melatonin. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20110401 |
Combined activity of oridonin and wogonin in advanced-stage ovarian cancer cells: sensitivity of ovarian cancer cells to phyto-active chemicals. | Cell biology and toxicology 20110401 |
A qualitative systematic review of the evidence base for non-cross-resistance between steroidal and non-steroidal aromatase inhibitors in metastatic breast cancer. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20110401 |
Tetra-methoxystilbene modulates ductal growth of the developing murine mammary gland. | Breast cancer research and treatment 20110401 |
Cyclic estrogenic fluctuation influences synaptic transmission of the medial vestibular nuclei in female rats. | Acta oto-laryngologica 20110401 |
Letrozole plus GnRH analogue as preoperative and adjuvant therapy in premenopausal women with ER positive locally advanced breast cancer. | Breast cancer research and treatment 20110401 |
Combination of trastuzumab and letrozole after resistance to sequential trastuzumab and aromatase inhibitor monotherapies in patients with estrogen receptor-positive, HER-2-positive advanced breast cancer: a proof-of-concept trial (SAKK 23/03). | Endocrine-related cancer 20110401 |
A gene expression signature from human breast cancer cells with acquired hormone independence identifies MYC as a mediator of antiestrogen resistance. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110401 |
Controlled ovarian hyperstimulation: a review for the non-ART patient. | Minerva ginecologica 20110401 |
ESR1 is co-expressed with closely adjacent uncharacterised genes spanning a breast cancer susceptibility locus at 6q25.1. | PLoS genetics 20110401 |
[Neoadjuvant endocrine therapy for postmenopausal estrogen receptor-positive patients with breast cancer]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110401 |
Differences between the non-steroidal aromatase inhibitors anastrozole and letrozole--of clinical importance? | British journal of cancer 20110329 |
Design, synthesis, and biological evaluation of imidazolyl derivatives of 4,7-disubstituted coumarins as aromatase inhibitors selective over 17-α-hydroxylase/C17-20 lyase. | Journal of medicinal chemistry 20110324 |
Analyses adjusting for selective crossover show improved overall survival with adjuvant letrozole compared with tamoxifen in the BIG 1-98 study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110320 |
Testosterone dependent androgen receptor stabilization and activation of cell proliferation in primary human myometrial microvascular endothelial cells. | Fertility and sterility 20110315 |
The potency and clinical efficacy of aromatase inhibitors across the breast cancer continuum. | Annals of oncology : official journal of the European Society for Medical Oncology 20110301 |
The unitary model for estrogen deficiency and the pathogenesis of osteoporosis: is a revision needed? | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20110301 |
Increase in formalin-induced tonic pain by 5alpha-reductase and aromatase inhibition in female rats. | Pharmacology, biochemistry, and behavior 20110301 |
Functional activation of the estrogen receptor-α and aromatase by the HDAC inhibitor entinostat sensitizes ER-negative tumors to letrozole. | Cancer research 20110301 |
Recent advances in anti-angiogenic therapy of cancer. | Oncotarget 20110301 |
[A case of secondary inflammatory breast cancer with multiple metastases in which operation was possible through letrozole monotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110301 |
[A case of possible retroperitoneal metastasis of breast cancer successfully treated with oral S-1 and cyclophosphamide therapy after TC therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110301 |
Eight-year follow-up of a girl with McCune-Albright syndrome. | Journal of clinical research in pediatric endocrinology 20110301 |
[Aromatase inhibitors and arthralgia]. | Magyar onkologia 20110301 |
Adjuvant endocrine therapy in postmenopausal breast cancer patients: does hormone receptor status influence decision-making? | Critical reviews in oncology/hematology 20110201 |
Prolonged survival of neoplastic meningitis from breast cancer with letrozole and intrathecal methotrexate: a case report. | Journal of neuro-oncology 20110201 |
Neoadjuvant pegylated liposomal doxorubicin in combination with cisplatin and infusional fluoruracil (CCF) with and without endocrine therapy in locally advanced primary or recurrent breast cancer. | Breast (Edinburgh, Scotland) 20110201 |
Anastrozole and letrozole: an investigation and comparison of quality of life and tolerability. | Breast cancer research and treatment 20110201 |
The effect of aromatase inhibitor letrozole on body mass index, serum hormones, and sperm parameters in infertile men. | Fertility and sterility 20110201 |
Cognitive function in postmenopausal breast cancer patients one year after completing adjuvant endocrine therapy with letrozole and/or tamoxifen in the BIG 1-98 trial. | Breast cancer research and treatment 20110201 |
Expression of P-450 aromatase, estrogen receptor α and β, and α-inhibin in the fetal baboon testis after estrogen suppression during the second half of gestation. | Endocrine 20110201 |
Misoprostol with or without letrozole pretreatment for termination of pregnancy: a randomized controlled trial. | Obstetrics and gynecology 20110201 |
[Eosinophilic colitis associated with letrozole]. | Gastroenterologia y hepatologia 20110201 |
[Significance of HER2 testing in breast cancer]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20110201 |
The Role of MicroRNAs in Regulatory T Cells and in the Immune Response. | Immune network 20110201 |
Increased 5α-reductase type 2 expression in human breast carcinoma following aromatase inhibitor therapy: the correlation with decreased tumor cell proliferation. | Hormones & cancer 20110201 |
Successful use of biweekly gemcitabine plus nab-paclitaxel in two male patients with stage iv breast cancer: case reports and review of the literature. | American journal of therapeutics 20110101 |
Failure to perceive increased risk of fracture in women 55 years and older: the Global Longitudinal Study of Osteoporosis in Women (GLOW). | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20110101 |
Predictors of non-adherence to aromatase inhibitors among commercially insured women with breast cancer. | Breast cancer research and treatment 20110101 |
Regulation of circulating sclerostin levels by sex steroids in women and in men. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20110101 |
Aromatase inhibitors in recurrent ovarian endometriomas: report of five cases with literature review. | Fertility and sterility 20110101 |
Rheumatoid arthritis and aromatase inhibitors. | Joint, bone, spine : revue du rhumatisme 20110101 |
Comparison of aromatase inhibitor (letrozole) and immunomodulators (infliximab and etanercept) on the regression of endometriotic implants in a rat model. | European journal of obstetrics, gynecology, and reproductive biology 20110101 |
A pilot study on the use of letrozole with either misoprostol or mifepristone for termination of pregnancy up to 63 days. | Contraception 20110101 |
Manipulating protein acetylation in breast cancer: a promising approach in combination with hormonal therapies? | Journal of biomedicine & biotechnology 20110101 |
A time series evaluation of the in vivo effect of letrozole on gene expression in breast cancer. | Pharmacogenomics 20110101 |
Saddle pulmonary embolism in a cancer patient with thrombocytopenia: a treatment dilemma. | Cardiology research and practice 20110101 |
Association of basal serum testosterone levels with ovarian response and in vitro fertilization outcome. | Reproductive biology and endocrinology : RB&E 20110101 |
Association of functional polymorphisms in CYP19A1 with aromatase inhibitor associated arthralgia in breast cancer survivors. | Breast cancer research : BCR 20110101 |
Chemoprevention of hormone receptor-negative breast cancer: new approaches needed. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20110101 |
Tumor-specific HMG-CoA reductase expression in primary premenopausal breast cancer predicts response to tamoxifen. | Breast cancer research : BCR 20110101 |
Olive oil effectively mitigates ovariectomy-induced osteoporosis in rats. | BMC complementary and alternative medicine 20110101 |
Identification of candidate small-molecule therapeutics to cancer by gene-signature perturbation in connectivity mapping. | PloS one 20110101 |
Treatment options for polycystic ovary syndrome. | International journal of women's health 20110101 |
Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer. | Breast cancer research : BCR 20110101 |
Do aromatase inhibitors have adverse effects on cognitive function? | Breast cancer research : BCR 20110101 |
Predictive value of pathological and immunohistochemical parameters for axillary lymph node metastasis in breast carcinoma. | Diagnostic pathology 20110101 |
Conceptual aspects of large meta-analyses with publicly available microarray data: a case study in oncology. | Bioinformatics and biology insights 20110101 |
Significant survival improvement of patients with recurrent breast cancer in the periods 2001-2008 vs. 1992-2000. | BMC cancer 20110101 |
Aromatase inhibitor-associated bone and musculoskeletal effects: new evidence defining etiology and strategies for management. | Breast cancer research : BCR 20110101 |
Breast cancer, sickness absence, income and marital status. A study on life situation 1 year prior diagnosis compared to 3 and 5 years after diagnosis. | PloS one 20110101 |
Cerebellar degeneration as presenting symptom of recurrent endometrial stromal sarcoma with sex-cord elements. | Case reports in neurology 20110101 |
Quantitative in vivo assessment of radiation injury of the liver using Gd-EOB-DTPA enhanced MRI: tolerance dose of small liver volumes. | Radiation oncology (London, England) 20110101 |
A synergistic antiproliferation effect of curcumin and docosahexaenoic acid in SK-BR-3 breast cancer cells: unique signaling not explained by the effects of either compound alone. | BMC cancer 20110101 |
Change in HER-2/neu Status from Negative to Positive following Treatment in Breast Cancer: A Case Report. | Case reports in oncology 20110101 |
Goserelin plus letrozole as first- or second-line hormonal treatment in premenopausal patients with advanced breast cancer. | Endocrine journal 20110101 |
Biological Markers in DCIS and Risk of Breast Recurrence: A Systematic Review. | Journal of Cancer 20110101 |
Tamoxifen in early-stage estrogen receptor-positive breast cancer: overview of clinical use and molecular biomarkers for patient selection. | OncoTargets and therapy 20110101 |
Intussusception of the small bowel secondary to malignant metastases in two 80-year-old people: a case series. | Journal of medical case reports 20110101 |
Dehydroepiandrosterone (DHEA) supplementation in diminished ovarian reserve (DOR). | Reproductive biology and endocrinology : RB&E 20110101 |
Interpreting Breast International Group (BIG) 1-98: a randomized, double-blind, phase III trial comparing letrozole and tamoxifen as adjuvant endocrine therapy for postmenopausal women with hormone receptor-positive, early breast cancer. | Breast cancer research : BCR 20110101 |
Biomarkers of radiosensitivity in a-bomb survivors pregnant at the time of bombings in hiroshima and nagasaki. | ISRN obstetrics and gynecology 20110101 |
High-response intrauterine insemination cycles converted to low-cost in vitro fertilization. | Journal of multidisciplinary healthcare 20110101 |
GP88 (PC-Cell Derived Growth Factor, progranulin) stimulates proliferation and confers letrozole resistance to aromatase overexpressing breast cancer cells. | BMC cancer 20110101 |
Malignancy-associated dyslipidemia. | The open cardiovascular medicine journal 20110101 |
PI3K pathway activation results in low efficacy of both trastuzumab and lapatinib. | BMC cancer 20110101 |
[Assessment of the quality of life of women with breast cancer in adjuvant treatment with tamoxifen or aromatase inhibitors--a randomized trial]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20110101 |
Individualised controlled ovarian stimulation (iCOS): maximising success rates for assisted reproductive technology patients. | Reproductive biology and endocrinology : RB&E 20110101 |
Hormonal, follicular and endometrial dynamics in letrozole-treated versus natural cycles in patients undergoing controlled ovarian stimulation. | Reproductive biology and endocrinology : RB&E 20110101 |
Extended letrozole regimen versus clomiphene citrate for superovulation in patients with unexplained infertility undergoing intrauterine insemination: a randomized controlled trial. | Reproductive biology and endocrinology : RB&E 20110101 |
Aromatase inhibitors in stimulated IVF cycles. | Reproductive biology and endocrinology : RB&E 20110101 |
Letrozole or clomiphene citrate as first line for anovulatory infertility: a debate. | Reproductive biology and endocrinology : RB&E 20110101 |
The emerging use of aromatase inhibitors for endometriosis treatment. | Reproductive biology and endocrinology : RB&E 20110101 |
Letrozole and norethisterone acetate versus letrozole and triptorelin in the treatment of endometriosis related pain symptoms: a randomized controlled trial. | Reproductive biology and endocrinology : RB&E 20110101 |
Use of aromatase inhibitors to treat endometriosis-related pain symptoms: a systematic review. | Reproductive biology and endocrinology : RB&E 20110101 |
Aromatase inhibitors in post-menopausal endometriosis. | Reproductive biology and endocrinology : RB&E 20110101 |
Potential utility of natural products as regulators of breast cancer-associated aromatase promoters. | Reproductive biology and endocrinology : RB&E 20110101 |
Aromatase inhibitors and antiepileptic drugs: a computational systems biology analysis. | Reproductive biology and endocrinology : RB&E 20110101 |
Aromatase inhibitors in men: effects and therapeutic options. | Reproductive biology and endocrinology : RB&E 20110101 |
Promising molecular targeted therapies in breast cancer. | Indian journal of pharmacology 20110101 |
Targeted treatment of recurrent platinum-resistant ovarian cancer: current and emerging therapies. | Cancer management and research 20110101 |
Prospective evaluation of serum tissue inhibitor of metalloproteinase 1 and carbonic anhydrase IX in correlation to circulating tumor cells in patients with metastatic breast cancer. | Breast cancer research : BCR 20110101 |
Dose and polymorphic genes xrcc1, xrcc3, gst play a role in the risk of articledeveloping erythema in breast cancer patients following single shot partial breast irradiation after conservative surgery. | BMC cancer 20110101 |
Multiple treatment comparison meta-analyses: a step forward into complexity. | Clinical epidemiology 20110101 |
Aromatase activity and bone loss in men. | Journal of osteoporosis 20110101 |
Breast Cancer Profile in a Group of Patients Followed up at the Radiation Therapy Unit of the Yaounde General Hospital, Cameroon. | Obstetrics and gynecology international 20110101 |
Microarray-based oncogenic pathway profiling in advanced serous papillary ovarian carcinoma. | PloS one 20110101 |
Innegligible musculoskeletal disorders caused by zoledronic acid in adjuvant breast cancer treatment: a meta-analysis. | Journal of experimental & clinical cancer research : CR 20110101 |
Ki67 proliferation in core biopsies versus surgical samples - a model for neo-adjuvant breast cancer studies. | BMC cancer 20110101 |
Roscovitine confers tumor suppressive effect on therapy-resistant breast tumor cells. | Breast cancer research : BCR 20110101 |
Government use licenses in Thailand: an assessment of the health and economic impacts. | Globalization and health 20110101 |
Estrogen receptor degradation: a CUE for endocrine resistance? | Breast cancer research : BCR 20110101 |
Increased fracture rate in women with breast cancer: a review of the hidden risk. | BMC cancer 20110101 |
Vitamin D and breast cancer: interpreting current evidence. | Breast cancer research : BCR 20110101 |
A rare case of zolendronate infusion complication leading to glaucoma filtration surgery. | Clinical ophthalmology (Auckland, N.Z.) 20110101 |
Current and emerging treatments for uterine myoma - an update. | International journal of women's health 20110101 |
Clinical relevance of 'withdrawal therapy' as a form of hormonal manipulation for breast cancer. | World journal of surgical oncology 20110101 |
Government use licenses in Thailand: The power of evidence, civil movement and political leadership. | Globalization and health 20110101 |
In Silico discovery of transcription factors as potential diagnostic biomarkers of ovarian cancer. | BMC systems biology 20110101 |
erbB3 recruitment of insulin receptor substrate 1 modulates insulin-like growth factor receptor signalling in oestrogen receptor-positive breast cancer cell lines. | Breast cancer research : BCR 20110101 |
Platinum resistance in breast and ovarian cancer cell lines. | Journal of experimental & clinical cancer research : CR 20110101 |
A novel mouse model of Alzheimer's disease with chronic estrogen deficiency leads to glial cell activation and hypertrophy. | Journal of aging research 20110101 |
Pharmacogenetic testing affects choice of therapy among women considering tamoxifen treatment. | Genome medicine 20110101 |
Flare hypercalcemia after letrozole in a patient with liver metastasis from breast cancer: a case report. | Journal of medical case reports 20110101 |
Methadone adverse reaction presenting with large increase in plasma methadone binding: a case series. | Journal of medical case reports 20110101 |
The time since last menstrual period is important as a clinical predictor for non-steroidal aromatase inhibitor-related arthralgia. | BMC cancer 20110101 |
Lapatinib in the treatment of HER-2 overexpressing breast cancer. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20110101 |
Male breast carcinoma: increased awareness needed. | Breast cancer research : BCR 20110101 |
Ovulation induction with minimal dose of follitropin alfa: a case series study. | Reproductive biology and endocrinology : RB&E 20110101 |
Predictive immunohistochemical biomarkers in the context of neoadjuvant therapy for breast cancer. | Journal of the National Cancer Institute. Monographs 20110101 |
Neoadjuvant chemotherapy and targeted therapies: a promising strategy. | Journal of the National Cancer Institute. Monographs 20110101 |
Parallel screening of FDA-approved antineoplastic drugs for identifying sensitizers of TRAIL-induced apoptosis in cancer cells. | BMC cancer 20110101 |
Altered expression of insulin receptor isoforms in breast cancer. | PloS one 20110101 |
Lobular carcinoma of the breast metastasizing to leiomyoma in a patient under letrozole treatment. | European journal of gynaecological oncology 20110101 |
Toxicity and cosmesis outcomes after single fraction partial breast irradiation in early stage breast cancer. | Radiation oncology (London, England) 20110101 |
Exemestane in the adjuvant treatment of breast cancer in postmenopausal women. | Breast cancer : basic and clinical research 20110101 |
Mutations in the phosphatidylinositol 3-kinase pathway: role in tumor progression and therapeutic implications in breast cancer. | Breast cancer research : BCR 20110101 |
Phase I-II study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell cancer. | BMC cancer 20110101 |
Regulation of breast cancer metastasis by Runx2 and estrogen signaling: the role of SNAI2. | Breast cancer research : BCR 20110101 |
Lapatinib and trastuzumab in combination with an aromatase inhibitor for the first-line treatment of metastatic hormone receptor-positive breast cancer which over-expresses human epidermal growth factor 2 (HER2): a systematic review and economic analysis. | Health technology assessment (Winchester, England) 20110101 |
The protective effect of zoledronic acid on bone loss in postmenopausal women with early breast cancer treated with sequential tamoxifen and letrozole: a prospective, randomized, phase II trial. | Oncology 20110101 |
Efficacy and safety of ultra-low-dose Vagifem (10 mcg). | Patient preference and adherence 20110101 |
The use of high dose letrozole in ovulation induction and controlled ovarian hyperstimulation. | ISRN obstetrics and gynecology 20110101 |
Cryopreservation and fertility: current and prospective possibilities for female cancer patients. | ISRN obstetrics and gynecology 20110101 |
Luminal-B breast cancer and novel therapeutic targets. | Breast cancer research : BCR 20110101 |
Regression of late onset choroidal metastasis from a breast carcinoma with letrozole. | Case reports in ophthalmology 20110101 |
Rosiglitazone and pioglitazone alter aromatase kinetic properties in human granulosa cells. | PPAR research 20110101 |
Review of breast conservation therapy: then and now. | ISRN oncology 20110101 |
Testis morphology in rats chronically treated with letrozole, an aromatase inhibitor. | Folia histochemica et cytobiologica 20110101 |
The state of research into children with cancer across Europe: new policies for a new decade. | Ecancermedicalscience 20110101 |
Endocrine-responsive breast cancer: a 28-year Odyssey. | Ecancermedicalscience 20110101 |
Breast conservation surgery: state of the art. | International journal of breast cancer 20110101 |
A role for estrogen receptor phosphorylation in the resistance to tamoxifen. | International journal of breast cancer 20110101 |
Autophagy: friend or foe in breast cancer development, progression, and treatment. | International journal of breast cancer 20110101 |
The Role of Interferon Regulatory Factor-1 (IRF1) in Overcoming Antiestrogen Resistance in the Treatment of Breast Cancer. | International journal of breast cancer 20110101 |
Joint symptoms, aromatase inhibitor-related adverse reactions, are indirectly associated with decreased serum estradiol. | International journal of surgical oncology 20110101 |
[Effectiveness of aromatase inhibitors in comparison with metformin for neoadjuvant treatment in patients with endometrial cancer]. | Voprosy onkologii 20110101 |
Neuroprotective actions of neurosteroids. | Frontiers in endocrinology 20110101 |
Combination of acupuncture and chinese medicinal herbs in treating model rats with polycystic ovary syndrome. | African journal of traditional, complementary, and alternative medicines : AJTCAM 20110101 |
The insulin receptor: a new target for cancer therapy. | Frontiers in endocrinology 20110101 |
Cell death signaling and anticancer therapy. | Frontiers in oncology 20110101 |
Rare case of ER positive colorectal stricture demonstrating improvement with letrozole. | BMJ case reports 20110101 |
Hippocampal synthesis of sex steroids and corticosteroids: essential for modulation of synaptic plasticity. | Frontiers in endocrinology 20110101 |
Roles of 17ß-estradiol involve regulation of reelin expression and synaptogenesis in the dentate gyrus. | Cerebral cortex (New York, N.Y. : 1991) 20101201 |
Effects of estrogen and testosterone on resting energy expenditure in older men. | Obesity (Silver Spring, Md.) 20101201 |
Aromatase inhibitors in women with clomiphene citrate resistance: a randomized, double-blind, placebo-controlled trial. | Fertility and sterility 20101201 |
Minimizing early relapse and maximizing treatment outcomes in hormone-sensitive postmenopausal breast cancer: efficacy review of AI trials. | Cancer metastasis reviews 20101201 |
Oncogenic HER2{Delta}16 suppresses miR-15a/16 and deregulates BCL-2 to promote endocrine resistance of breast tumors. | Carcinogenesis 20101201 |
Design, synthesis and structure-activity relationship study of novel pyrazole-based heterocycles as potential antitumor agents. | European journal of medicinal chemistry 20101201 |
Fertility preservation in women with breast cancer. | Clinical obstetrics and gynecology 20101201 |
Phase II trial of combination of pegylated liposomal doxorubicin, cisplatin, and infusional 5-fluorouracil (CCF) plus trastuzumab as preoperative treatment for locally advanced and inflammatory breast cancer. | Clinical breast cancer 20101201 |
[Advanced breast cancer in a patient achieving long-term SD after letrozole administration for liver metastasis developing during anastrozole therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101201 |
Lapatinib in breast cancer - the predictive significance of HER1 (EGFR), HER2, PTEN and PIK3CA genes and lapatinib plasma level assessment. | Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20101201 |
Biological reprogramming in acquired resistance to endocrine therapy of breast cancer. | Oncogene 20101111 |
The role of microRNA-128a in regulating TGFbeta signaling in letrozole-resistant breast cancer cells. | Breast cancer research and treatment 20101101 |
Synergistic activity of letrozole and sorafenib on breast cancer cells. | Breast cancer research and treatment 20101101 |
Efficacy of zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole: 36-month results of the ZO-FAST Study. | Annals of oncology : official journal of the European Society for Medical Oncology 20101101 |
46,XX/SRY-negative true hermaphrodite. | Fertility and sterility 20101101 |
Management of ErbB2-positive breast cancer: insights from preclinical and clinical studies with lapatinib. | Japanese journal of clinical oncology 20101101 |
Letrozole versus laparoscopic ovarian diathermy for ovulation induction in clomiphene-resistant women with polycystic ovary syndrome: a randomized controlled trial. | Archives of gynecology and obstetrics 20101101 |
Effects of suppression of follicle-stimulating hormone secretion on bone resorption markers in postmenopausal women. | The Journal of clinical endocrinology and metabolism 20101101 |
In utero exposure to bisphenol A shifts the window of susceptibility for mammary carcinogenesis in the rat. | Environmental health perspectives 20101101 |
Cognitive changes associated with endocrine therapy for breast cancer. | Maturitas 20101101 |
Unique distribution of aromatase in the human brain: in vivo studies with PET and [N-methyl-11C]vorozole. | Synapse (New York, N.Y.) 20101101 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
The pregnancy outcome of retrieved excess eggs collected during selective follicular reduction from patients with three or more preovulatory follicles undergoing controlled ovarian stimulation and IUI. | Human reproduction (Oxford, England) 20101101 |
Effect of letrozole on plasma lipids, triglycerides, and estradiol in postmenopausal women with metastatic breast cancer. | The oncologist 20101101 |
Optimal sequence of implied modalities in the adjuvant setting of breast cancer treatment: an update on issues to consider. | The oncologist 20101101 |
Optimizing clinical benefits of bisphosphonates in cancer patients with bone metastases. | The oncologist 20101101 |
Endometrioid ovarian carcinoma benefits from aromatase inhibitors: case report and literature review. | Current oncology (Toronto, Ont.) 20101101 |
[Indoleamine 2,3-dioxygenase activity during chemotherapy or hormone therapy in patients with breast cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
3-Ethyl-4-[3-(1H-imidazol-1-yl)prop-yl]-5-phenyl-4H-1,2,4-triazole dihydrate. | Acta crystallographica. Section E, Structure reports online 20101101 |
Effects of estrogen on breast cancer development: Role of estrogen receptor independent mechanisms. | International journal of cancer 20101015 |
Evaluation of treatment-effect heterogeneity using biomarkers measured on a continuous scale: subpopulation treatment effect pattern plot. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101010 |
Cognitive function in postmenopausal women receiving adjuvant letrozole or tamoxifen for breast cancer in the BIG 1-98 randomized trial. | Breast (Edinburgh, Scotland) 20101001 |
The influence of high-normal testosterone levels on risk-taking in healthy males in a 1-week letrozole administration study. | Psychoneuroendocrinology 20101001 |
COX-2 inhibitor nimesulide analogs are aromatase suppressors in breast cancer cells. | The Journal of steroid biochemistry and molecular biology 20101001 |
Peripubertal aromatase inhibition in male rats has adverse long-term effects on bone strength and growth and induces prostatic hyperplasia. | The Journal of endocrinology 20101001 |
Development and validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of tamoxifen, anastrozole, and letrozole in human plasma and its application to a clinical study. | Analytical and bioanalytical chemistry 20101001 |
Cost effectiveness of letrozole versus anastrozole in postmenopausal women with HR+ early-stage breast cancer. | Current medical research and opinion 20101001 |
Endocrine therapy for male breast cancer: rates of toxicity and adherence. | Current oncology (Toronto, Ont.) 20101001 |
N-[(4-Amino-5-sulfanyl-idene-4,5-dihydro-1H-1,2,4-triazol-3-yl)meth-yl]-4-methyl-benzamide. | Acta crystallographica. Section E, Structure reports online 20101001 |
3,3'-Dimethyl-4,4'-(hexane-1,6-di-yl)bis-[1H-1,2,4-triazol-5(4H)-one]. | Acta crystallographica. Section E, Structure reports online 20101001 |
A prospective study of aromatase inhibitor-associated musculoskeletal symptoms and abnormalities on serial high-resolution wrist ultrasonography. | Cancer 20100915 |
Preparation, characterization, and biodistribution of letrozole loaded PLGA nanoparticles in Ehrlich Ascites tumor bearing mice. | International journal of pharmaceutics 20100915 |
Neoadjuvant endocrine therapy in primary breast cancer: indications and use as a research tool. | British journal of cancer 20100907 |
Letrozole versus combined metformin and clomiphene citrate for ovulation induction in clomiphene-resistant women with polycystic ovary syndrome: a randomized controlled trial. | Fertility and sterility 20100901 |
ETAR antagonist ZD4054 exhibits additive effects with aromatase inhibitors and fulvestrant in breast cancer therapy, and improves in vivo efficacy of anastrozole. | Breast cancer research and treatment 20100901 |
The transdermal patches for site-specific delivery of letrozole: a new option for breast cancer therapy. | AAPS PharmSciTech 20100901 |
Bicalutamide and third-generation aromatase inhibitors in testotoxicosis. | Pediatrics 20100901 |
Lapatinib plus capecitabine in women with HER-2-positive advanced breast cancer: final survival analysis of a phase III randomized trial. | The oncologist 20100901 |
Quality of life in hormone receptor-positive HER-2+ metastatic breast cancer patients during treatment with letrozole alone or in combination with lapatinib. | The oncologist 20100901 |
Optimal adjuvant hormonal therapy in postmenopausal women with hormone-receptor-positive early breast cancer: have we answered the question? | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20100901 |
Down-regulation of heat-shock protein 70 (HSP-70) correlated with responsiveness to neoadjuvant aromatase inhibitor therapy in breast cancer patients. | Anticancer research 20100901 |
Gastric tumor from metastasis of breast cancer. | Anticancer research 20100901 |
GnRH antagonist/letrozole versus microdose GnRH agonist flare protocol in poor responders undergoing in vitro fertilization. | Taiwanese journal of obstetrics & gynecology 20100901 |
The pro-metastatic protein anterior gradient-2 predicts poor prognosis in tamoxifen-treated breast cancers. | Oncogene 20100826 |
Isoflurane preconditioning neuroprotection in experimental focal stroke is androgen-dependent in male mice. | Neuroscience 20100825 |
Biological evidence for dual antiangiogenic-antiaromatase activity of the VEGFR inhibitor PTK787/ZK222584 in vivo. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100815 |
Sex steroids affect triglyceride handling, glucose-dependent insulinotropic polypeptide, and insulin sensitivity: a 1-week randomized clinical trial in healthy young men. | Diabetes care 20100801 |
Use of aromatase inhibitors in children and adolescents: what's new? | Current opinion in pediatrics 20100801 |
Systematic review of aromatase inhibitors in the first-line treatment for hormone sensitive advanced or metastatic breast cancer. | Breast cancer research and treatment 20100801 |
Letrozole for ovulation induction and controlled ovarian hyperstimulation. | Current opinion in obstetrics & gynecology 20100801 |
Pilot trial of preoperative (neoadjuvant) letrozole in combination with bevacizumab in postmenopausal women with newly diagnosed estrogen receptor- or progesterone receptor-positive breast cancer. | Clinical breast cancer 20100801 |
Lapatinib and breast cancer: current indications and outlook for the future. | Expert review of anticancer therapy 20100801 |
Early recurrence risk: aromatase inhibitors versus tamoxifen. | Expert review of anticancer therapy 20100801 |
McCune-Albright syndrome (MAS): early and extensive bone fibrous dysplasia involvement and 'mistaken identity' oophorectomy. | Journal of pediatric endocrinology & metabolism : JPEM 20100801 |
Lapatinib: in postmenopausal women with hormone receptor-positive, HER2-positive metastatic breast cancer. | Drugs 20100730 |
Inflammatory cytokines and aromatase inhibitor-associated musculoskeletal syndrome: a case-control study. | British journal of cancer 20100727 |
Luteal support with intravaginal progesterone increases clinical pregnancy rates in women with polycystic ovary syndrome using letrozole for ovulation induction. | Fertility and sterility 20100701 |
A simple, selective and rapid validated method for estimation of anastrazole in human plasma by liquid chromatography-tandem mass spectrometry and its application to bioequivalence study. | Biomedical chromatography : BMC 20100701 |
Economic evaluation of zoledronic acid for the prevention of osteoporotic fractures in postmenopausal women with early-stage breast cancer receiving aromatase inhibitors in the UK. | Annals of oncology : official journal of the European Society for Medical Oncology 20100701 |
Vertebral morphology in aromatase inhibitor-treated males with idiopathic short stature or constitutional delay of puberty. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20100701 |
Synthesis and structure-activity relationship studies of pyrazole-based heterocycles as antitumor agents. | Archiv der Pharmazie 20100701 |
Vitamin D deficiency and bone mineral density in postmenopausal women receiving aromatase inhibitors for early breast cancer. | Maturitas 20100701 |
Cognitive effects of aromatase inhibitor therapy in peripubertal boys. | European journal of endocrinology 20100701 |
Control of mammary stem cell function by steroid hormone signalling. | Nature 20100610 |
Exemestane as first-line therapy in postmenopausal women with recurrent or metastatic breast cancer. | American journal of clinical oncology 20100601 |
Aromatase inhibition in male breast cancer patients: biological and clinical implications. | Annals of oncology : official journal of the European Society for Medical Oncology 20100601 |
Assessment of chemical effects on aromatase activity using the H295R cell line. | Environmental science and pollution research international 20100601 |
Letrozole and norethisterone acetate in colorectal endometriosis. | European journal of obstetrics, gynecology, and reproductive biology 20100601 |
Cyclin D1 regulates hepatic estrogen and androgen metabolism. | American journal of physiology. Gastrointestinal and liver physiology 20100601 |
GnRH agonist trigger for women with breast cancer undergoing fertility preservation by aromatase inhibitor/FSH stimulation. | Reproductive biomedicine online 20100601 |
Phase II parallel group study showing comparable efficacy between premenopausal metastatic breast cancer patients treated with letrozole plus goserelin and postmenopausal patients treated with letrozole alone as first-line hormone therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100601 |
Gene expression profiling and prediction of response to hormonal neoadjuvant treatment with anastrozole in surgically resectable breast cancer. | Breast cancer research and treatment 20100601 |
Ethyl 4-(3-ethyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-4-yl)benzoate. | Acta crystallographica. Section E, Structure reports online 20100601 |
Effect of aromatase inhibitors on ectopic endometrial growth and peritoneal environment in a mouse model of endometriosis. | Fertility and sterility 20100515 |
Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19). | Bioorganic & medicinal chemistry letters 20100515 |
Adjuvant aromatase inhibitor therapy: outcomes and safety. | Cancer treatment reviews 20100501 |
Letrozole monotherapy in the treatment of uterine myomas. | Fertility and sterility 20100501 |
Letrozole inhibits the osteogenesis of medullary bone in prelay pullets. | Poultry science 20100501 |
Breast cancer in the personal genomics era. | Current genomics 20100501 |
5-(4-Chloro-phen-yl)-3-(2,4-dimethyl-thiazol-5-yl)-1,2,4-triazolo[3,4-a]isoquinoline. | Acta crystallographica. Section E, Structure reports online 20100501 |
EGFR/HER2 inhibitor AEE788 increases ER-mediated transcription in HER2/ER-positive breast cancer cells but functions synergistically with endocrine therapy. | British journal of cancer 20100413 |
The effects of letrozole and melatonin on surgically induced endometriosis in a rat model: a preliminary study. | Fertility and sterility 20100401 |
A randomized, placebo-controlled trial (NCIC CTG MAP1) examining the effects of letrozole on mammographic breast density and other end organs in postmenopausal women. | Breast cancer research and treatment 20100401 |
Zoledronic acid for treatment of osteopenia and osteoporosis in women with primary breast cancer undergoing adjuvant aromatase inhibitor therapy. | Breast (Edinburgh, Scotland) 20100401 |
Preoperative therapy with trastuzumab and oral vinorelbine (+/- endocrine therapy) in patients with HER2-positive breast cancer. | Breast (Edinburgh, Scotland) 20100401 |
The effects of metformin and letrozole on endometriosis and comparison of the two treatment agents in a rat model. | Human reproduction (Oxford, England) 20100401 |
Analysis of hormone antagonists in clinical and municipal wastewater by isotopic dilution liquid chromatography tandem mass spectrometry. | Analytical and bioanalytical chemistry 20100401 |
Low levels of the herbicide atrazine alter sex ratios and reduce metamorphic success in Rana pipiens tadpoles raised in outdoor mesocosms. | Environmental health perspectives 20100401 |
Treatment of recurrent endometrial stromal sarcoma with letrozole: a case report and literature review. | Hormones & cancer 20100401 |
Combined effects of the bisphosphonate, zoledronic acid and the aromatase inhibitor letrozole on breast cancer cells in vitro: evidence of synergistic interaction. | British journal of cancer 20100316 |
Influence of pharmacogenetics on response and toxicity in breast cancer patients treated with doxorubicin and cyclophosphamide. | British journal of cancer 20100316 |
Analysis of spindle characteristics and embryo quality in mice stimulated with letrozole using Polscope imaging. | Fertility and sterility 20100315 |
Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template. | Journal of medicinal chemistry 20100311 |
Side-population cells in luminal-type breast cancer have tumour-initiating cell properties, and are regulated by HER2 expression and signalling. | British journal of cancer 20100302 |
Population pharmacokinetics of the humanised monoclonal antibody, HuHMFG1 (AS1402), derived from a phase I study on breast cancer. | British journal of cancer 20100302 |
Long-term endometrial effects in postmenopausal women with early breast cancer participating in the Intergroup Exemestane Study (IES)--a randomised controlled trial of exemestane versus continued tamoxifen after 2-3 years tamoxifen. | Annals of oncology : official journal of the European Society for Medical Oncology 20100301 |
Treatment of advanced uterine leiomyosarcoma with aromatase inhibitors. | Gynecologic oncology 20100301 |
Uterine and fetal blood flow indexes and fetal growth assessment after chronic estrogen suppression in the second half of baboon pregnancy. | American journal of physiology. Heart and circulatory physiology 20100301 |
Aromatase inhibitors induce spine synapse loss in the hippocampus of ovariectomized mice. | Endocrinology 20100301 |
Radiotherapy, antihormonal therapy, and personalised medicine. | The Lancet. Oncology 20100301 |
Concurrent or sequential adjuvant letrozole and radiotherapy after conservative surgery for early-stage breast cancer (CO-HO-RT): a phase 2 randomised trial. | The Lancet. Oncology 20100301 |
Formulation and biopharmaceutical evaluation of a transdermal patch containing letrozole. | Biopharmaceutics & drug disposition 20100301 |
[Management of metastatic HER2-positive breast cancer: present and future]. | Bulletin du cancer 20100301 |
Breast cancer drug approved for new indication. | Women's health (London, England) 20100301 |
Targeting signal transduction pathways in metastatic breast cancer: a comprehensive review. | The oncologist 20100301 |
Cryptic regulation of vasotocin neuronal activity but not anatomy by sex steroids and social stimuli in opportunistic desert finches. | Brain, behavior and evolution 20100301 |
[A case of postoperative liver metastasis of mucinous carcinoma of the breast with complete response to sequential administration of FEC75, tamoxifen citrate, and letrozole]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100301 |
Using pre-existing microarray datasets to increase experimental power: application to insulin resistance. | PLoS computational biology 20100301 |
Switching to letrozole versus continued tamoxifen therapy in treatment of postmenopausal women with early breast cancer. | Journal of the Egyptian National Cancer Institute 20100301 |
Aromatase resistance mechanisms in model systems in vivo. | The Journal of steroid biochemistry and molecular biology 20100227 |
Evaluation of plasma and tissue estrogen suppression with third-generation aromatase inhibitors: of relevance to clinical understanding? | The Journal of steroid biochemistry and molecular biology 20100227 |
Impact of aromatase inhibitors on bone health in breast cancer patients. | The Journal of steroid biochemistry and molecular biology 20100227 |
Molecular characterization of aromatase inhibitor-resistant, tamoxifen-resistant and LTEDaro cell lines. | The Journal of steroid biochemistry and molecular biology 20100227 |
Assessment of fracture risk in women with breast cancer using current vs emerging guidelines. | British journal of cancer 20100216 |
Low-molecular-weight cyclin E can bypass letrozole-induced G1 arrest in human breast cancer cells and tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100215 |
Potential role of UGT pharmacogenetics in cancer treatment and prevention: focus on tamoxifen and aromatase inhibitors. | Drug metabolism reviews 20100201 |
Feasibility trial of letrozole in combination with bevacizumab in patients with metastatic breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100201 |
Musculoskeletal manifestations in patients with malignant disease. | Clinical rheumatology 20100201 |
A study of the effects of the aromatase inhibitors anastrozole and letrozole on bone metabolism in postmenopausal women with estrogen receptor-positive breast cancer. | Breast cancer research and treatment 20100201 |
Switching from tamoxifen to aromatase inhibitors for adjuvant endocrine therapy in postmenopausal patients with early breast cancer. | Cancer treatment reviews 20100201 |
Effect of a switch of aromatase inhibitors on musculoskeletal symptoms in postmenopausal women with hormone-receptor-positive breast cancer: the ATOLL (articular tolerance of letrozole) study. | Breast cancer research and treatment 20100201 |
Screening of chemicals with anti-estrogenic activity using in vitro and in vivo vitellogenin induction responses in zebrafish (Danio rerio). | Chemosphere 20100201 |
Letrozole. | Expert opinion on drug metabolism & toxicology 20100201 |
Understanding resistance to endocrine agents: molecular mechanisms and potential for intervention. | Clinical breast cancer 20100201 |
Lapatinib plus letrozole as first-line therapy for HER-2+ hormone receptor-positive metastatic breast cancer. | The oncologist 20100201 |
Management of hot flashes in women with breast cancer. | Current oncology (Toronto, Ont.) 20100201 |
Management of aromatase inhibitor-induced arthralgia. | Current oncology (Toronto, Ont.) 20100201 |
Endometriosis: in search of optimal treatment. | Minerva ginecologica 20100201 |
1-Benzoyl-methyl-3-(2-thienylmeth-yl)-4-(2-thienylmethyl-eneamino)-1H-1,2,4-triazol-5(4H)-one. | Acta crystallographica. Section E, Structure reports online 20100201 |
Lack of association between oestrogen receptor polymorphisms and change in bone mineral density with tamoxifen therapy. | British journal of cancer 20100119 |
Sciatic nerve injury induces apoptosis of dorsal root ganglion satellite glial cells and selectively modifies neurosteroidogenesis in sensory neurons. | Glia 20100115 |
Association of BRCA1 mutations with occult primary ovarian insufficiency: a possible explanation for the link between infertility and breast/ovarian cancer risks. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100110 |
Cardiotoxicity of anticancer drugs: the need for cardio-oncology and cardio-oncological prevention. | Journal of the National Cancer Institute 20100106 |
Comparison of endocrine and ultrasound profiles during ovulation induction with clomiphene citrate and letrozole in ovulatory volunteer women. | Fertility and sterility 20100101 |
A randomized, controlled clinical trial comparing the effects of aromatase inhibitor (letrozole) and gonadotropin-releasing hormone agonist (triptorelin) on uterine leiomyoma volume and hormonal status. | Fertility and sterility 20100101 |
Effect of vitamin D supplementation on serum 25-hydroxy vitamin D levels, joint pain, and fatigue in women starting adjuvant letrozole treatment for breast cancer. | Breast cancer research and treatment 20100101 |
[Inhibiting effect of letrozole combined with curcumin on xenografted endometrial carcinoma growth in nude mice]. | Chinese journal of cancer 20100101 |
Sensitivity to the aromatase inhibitor letrozole is prolonged after a 'break' in treatment. | Molecular cancer therapeutics 20100101 |
T cell-prolymphocytic leukemia detected in a patient of breast cancer at the time of recurrence: a case report. | Cases journal 20100101 |
A polymorphism at the 3'-UTR region of the aromatase gene defines a subgroup of postmenopausal breast cancer patients with poor response to neoadjuvant letrozole. | BMC cancer 20100101 |
Molecular risk assessment of BIG 1-98 participants by expression profiling using RNA from archival tissue. | BMC cancer 20100101 |
Growth and reproductive outcomes in congenital adrenal hyperplasia. | International journal of pediatric endocrinology 20100101 |
Kypho-IORT--a novel approach of intraoperative radiotherapy during kyphoplasty for vertebral metastases. | Radiation oncology (London, England) 20100101 |
Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer. | Breast cancer research : BCR 20100101 |
Efficacy of letrozole in ovulation induction compared to that of clomiphene citrate in patients with polycystic ovarian syndrome. | The Journal of reproductive medicine 20100101 |
What the hyena's laugh tells: sex, age, dominance and individual signature in the giggling call of Crocuta crocuta. | BMC ecology 20100101 |
Cancer-drug associations: a complex system. | PloS one 20100101 |
Fertility preservation for cancer patients: a review. | Obstetrics and gynecology international 20100101 |
TIMP-1 and VEGF-165 serum concentration during first-line therapy of ovarian cancer patients. | BMC cancer 20100101 |
Management of anastrozole-induced bone loss in breast cancer patients with oral risedronate: results from the ARBI prospective clinical trial. | Breast cancer research : BCR 20100101 |
Hepatic breast cancer dissemination after an iatrogenic hepatic laceration during talc pleurodesis: a case report. | International archives of medicine 20100101 |
Erythrocyte alpha-tocopherol in breast cancer patients treated with letrozol. | Journal of nutritional science and vitaminology 20100101 |
Clomiphene citrate vs. letrozole for cryopreserved-thawed embryo transfer: a randomized, controlled trial. | The Journal of reproductive medicine 20100101 |
Responsiveness to PI3K and MEK inhibitors in breast cancer. Use of a 3D culture system to study pathways related to hormone independence in mice. | PloS one 20100101 |
Incidence of chemotherapy-induced amenorrhea associated with epirubicin, docetaxel and navelbine in younger breast cancer patients. | BMC cancer 20100101 |
EGFR isoforms and gene regulation in human endometrial cancer cells. | Molecular cancer 20100101 |
Managing bone mineral density with oral bisphosphonate therapy in women with breast cancer receiving adjuvant aromatase inhibition. | Breast cancer research : BCR 20100101 |
Isolated gastrointestinal metastasis of breast carcinoma: a case report. | Case reports in medicine 20100101 |
Symptomatic unilateral pleural effusion: A rare presentation of ovarian hyperstimulation syndrome. | Journal of human reproductive sciences 20100101 |
Recurrent endometrial stromal sarcoma: treatment with a progestin and gonadotropin releasing hormone agonist. | Sarcoma 20100101 |
A double-blind, placebo-controlled comparison of letrozole to oxandrolone effects upon growth and puberty of children with constitutional delay of puberty and idiopathic short stature. | Hormone research in paediatrics 20100101 |
Managing idiopathic short stature: role of somatropin (rDNA origin) for injection. | Biologics : targets & therapy 20100101 |
Changes in expression of oestrogen regulated and proliferation genes with neoadjuvant treatment highlight heterogeneity of clinical resistance to the aromatase inhibitor, letrozole. | Breast cancer research : BCR 20100101 |
Predictive relevance of HOXB13 protein expression for tamoxifen benefit in breast cancer. | Breast cancer research : BCR 20100101 |
Alternative strategies for the treatment of classical congenital adrenal hyperplasia: pitfalls and promises. | International journal of pediatric endocrinology 20100101 |
The differences in outcome between ATAC and BIG 1-98 suggest efficacy differences between these two nonsteroidal AIs. | Cancer investigation 20100101 |
Clinical practice decisions in endocrine therapy. | Cancer investigation 20100101 |
The Expression Patterns of ER, PR, HER2, CK5/6, EGFR, Ki-67 and AR by Immunohistochemical Analysis in Breast Cancer Cell Lines. | Breast cancer : basic and clinical research 20100101 |
Clomiphene citrate or aromatase inhibitors combined with gonadotropins for superovulation in women undergoing intrauterine insemination: a prospective randomised trial. | Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20100101 |
Post-operative breast cancer patients diagnosed with skeletal metastasis without bone pain had fewer skeletal-related events and deaths than those with bone pain. | BMC cancer 20100101 |
Treatment Options in Metastatic Renal Cell Carcinoma: Focus on mTOR Inhibitors. | Clinical Medicine Insights. Oncology 20100101 |
Recent advancement in nonsteroidal aromatase inhibitors for treatment of estrogen-dependent breast cancer. | Current medicinal chemistry 20100101 |
Molecular and therapeutic potential and toxicity of valproic acid. | Journal of biomedicine & biotechnology 20100101 |
Constitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancer. | PloS one 20100101 |
Ovarian steroid hormones: what's hot in the stem cell pool? | Breast cancer research : BCR 20100101 |
Musculoskeletal adverse events associated with adjuvant aromatase inhibitors. | Journal of oncology 20100101 |
The multikinase inhibitor Sorafenib displays significant antiproliferative effects and induces apoptosis via caspase 3, 7 and PARP in B- and T-lymphoblastic cells. | BMC cancer 20100101 |
Reduction of radiation pneumonitis by V20-constraints in breast cancer. | Radiation oncology (London, England) 20100101 |
Present and future evolution of advanced breast cancer therapy. | Breast cancer research : BCR 20100101 |
Women and bone health: maximizing the benefits of aromatase inhibitor therapy. | Oncology 20100101 |
Breast cancer in young women. | Breast cancer research : BCR 20100101 |
Antiangiogenic therapy for breast cancer. | Breast cancer research : BCR 20100101 |
Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells. | Breast cancer research : BCR 20100101 |
Predicting prognosis of breast cancer with gene signatures: are we lost in a sea of data? | Genome medicine 20100101 |
Impact of oral vitamin D supplementation on serum 25-hydroxyvitamin D levels in oncology. | Nutrition journal 20100101 |
The Brustkrebs-Studien.de website for breast cancer patients: User acceptance of a German internet portal offering information on the disease and treatment options, and a clinical trials matching service. | BMC cancer 20100101 |
Zoledronic acid: clinical utility and patient considerations in osteoporosis and low bone mass. | Drug design, development and therapy 20100101 |
Hot flashes in breast cancer survivors and an association with calcium supplement use. | International journal of women's health 20100101 |
Quality of life of breast cancer patients medicated with anti-estrogens, 2 years after acupuncture treatment: a qualitative study. | International journal of women's health 20100101 |
Minimising immunohistochemical false negative ER classification using a complementary 23 gene expression signature of ER status. | PloS one 20100101 |
Off-label use of aromatase inhibitors to promote taller stature: is it safe. | Hormone research in paediatrics 20100101 |
Prevention of bone metastases and management of bone health in early breast cancer. | Breast cancer research : BCR 20100101 |
Randomized adjuvant trials in oncology: a necessity or time-consuming luxury? | Breast cancer research : BCR 20100101 |
Genome-wide case-control study of musculoskeletal adverse events and functional genomics in women receiving aromatase inhibitors: going beyond associations. | Breast cancer research : BCR 20100101 |
Angiogenesis - still a worthwhile target for breast cancer therapy? | Breast cancer research : BCR 20100101 |
Anti-tumour activity of bisphosphonates in preclinical models of breast cancer. | Breast cancer research : BCR 20100101 |
Concurrent breast stroma sarcoma and breast carcinoma: a case report. | Journal of medical case reports 20100101 |
Tailoring adjuvant endocrine therapy for postmenopausal breast cancer: a CYP2D6 multiple-genotype-based modeling analysis and validation. | PloS one 20100101 |
Role of lapatinib in the first-line treatment of patients with metastatic breast cancer. | Cancer management and research 20100101 |
FACE: the barefaced facts of AI potency. | Cancer management and research 20100101 |
Improving management of patients with advanced cancer. | Patient preference and adherence 20100101 |
Comparative evaluation of pregnancy outcome in gonadotrophin-clomiphene combination vs clomiphene alone in polycystic ovarian syndrome and unexplained infertility-A prospective clinical trial. | Journal of human reproductive sciences 20100101 |
Inhibitory effect of flavonoids on mutant H-Rasp protein. | Bioinformation 20100101 |
Safety and tolerability of zoledronic acid and other bisphosphonates in osteoporosis management. | Drug, healthcare and patient safety 20100101 |
Effect of Aloe barbadensis Mill. formulation on Letrozole induced polycystic ovarian syndrome rat model. | Journal of Ayurveda and integrative medicine 20100101 |
Pharmacoeconomic considerations in the treatment of breast cancer. | ClinicoEconomics and outcomes research : CEOR 20100101 |
Spectrophotometric methods for the determination of letrozole in bulk and pharmaceutical dosage forms. | Journal of advanced pharmaceutical technology & research 20100101 |
IART (Intra-Operative Avidination for Radionuclide Therapy) for accelerated radiotherapy in breast cancer patients. Technical aspects and preliminary results of a phase II study with 90Y-labelled biotin. | Ecancermedicalscience 20100101 |
Metastatic disease causing unilateral isolated hypoglossal nerve palsy. | BMJ case reports 20100101 |
Role of aromatase inhibitors in the upfront adjuvant hormonal therapy of postmenopausal patients with breast cancer. | Indian journal of surgical oncology 20100101 |
Effects of oestradiol on gonadotrophin levels in normal and castrated men. | Clinical endocrinology 20091201 |
Increased androgen receptor and remodeling in the prostatic stroma after the inhibition of 5-alpha reductase and aromatase in gerbil ventral prostate. | Microscopy research and technique 20091201 |
Letrozole combined with norethisterone acetate compared with norethisterone acetate alone in the treatment of pain symptoms caused by endometriosis. | Human reproduction (Oxford, England) 20091201 |
CITED2 and NCOR2 in anti-oestrogen resistance and progression of breast cancer. | British journal of cancer 20091201 |
Hormonal deprivation therapy-induced osteoporosis in postmenopausal women with breast cancer. | Best practice & research. Clinical rheumatology 20091201 |
[A case of recurrent breast cancer with extensive liver metastasis successfully treated with endocrine therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091201 |
The role of regulatory T cells in cancer. | Immune network 20091201 |
Aromatase inhibitors to augment height: continued caution and study required. | Journal of clinical research in pediatric endocrinology 20091201 |
Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091120 |
Lapatinib monotherapy in patients with relapsed, advanced, or metastatic breast cancer: efficacy, safety, and biomarker results from Japanese patients phase II studies. | British journal of cancer 20091117 |
Impact of estrogen replacement on letrozole-induced embryopathic effects. | Human reproduction (Oxford, England) 20091101 |
Estrus cyclicity of spinogenesis: underlying mechanisms. | Journal of neural transmission (Vienna, Austria : 1996) 20091101 |
Fertility preservation for breast cancer patients. | Seminars in reproductive medicine 20091101 |
Hormonal therapy with letrozole prior to surgical management of recurrent metastatic low-grade endometrial stromal sarcoma (LGESS). | Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20091101 |
Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes. | Xenobiotica; the fate of foreign compounds in biological systems 20091101 |
Lapatinib plus letrozole for postmenopausal patients with advanced HER2(+)/HR(+) breast cancer. | Expert review of anticancer therapy 20091101 |
Retrospective analysis of concurrent vs. sequential administration of radiotherapy and hormone therapy using aromatase inhibitor for hormone receptor-positive postmenopausal breast cancer. | Anticancer research 20091101 |
Nuclear receptor co-activators and HER-2/neu are upregulated in breast cancer patients during neo-adjuvant treatment with aromatase inhibitors. | British journal of cancer 20091020 |
Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women. | The Cochrane database of systematic reviews 20091007 |
Clomiphene citrate or aromatase inhibitors for superovulation in women with unexplained infertility undergoing intrauterine insemination: a prospective randomized trial. | Fertility and sterility 20091001 |
Determination of the absolute configuration of aromatase and dual aromatase-sulfatase inhibitors by vibrational and electronic circular dichroism spectra analysis. | Chirality 20091001 |
Inhibition of drug metabolizing cytochrome P450s by the aromatase inhibitor drug letrozole and its major oxidative metabolite 4,4'-methanol-bisbenzonitrile in vitro. | Cancer chemotherapy and pharmacology 20091001 |
Immediate versus delayed zoledronic acid for prevention of bone loss in postmenopausal women with breast cancer starting letrozole after tamoxifen-N03CC. | Breast cancer research and treatment 20091001 |
Dehydroepiandrosterone inhibits the proliferation and induces the death of HPV-positive and HPV-negative cervical cancer cells through an androgen- and estrogen-receptor independent mechanism. | The FEBS journal 20091001 |
Aromatase inhibitor letrozole in synergy with curcumin in the inhibition of xenografted endometrial carcinoma growth. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20091001 |
Aromatase inhibitors for female infertility: a systematic review of the literature. | Reproductive biomedicine online 20091001 |
Use of aromatase inhibitors in poor-responder patients receiving GnRH antagonist protocols. | Reproductive biomedicine online 20091001 |
Update of the BIG 1-98 Trial: where do we stand? | Breast (Edinburgh, Scotland) 20091001 |
Tamoxifen: the drug that came in from the cold. | British journal of cancer 20090915 |
Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells. | Blood 20090910 |
Clomiphene citrate or letrozole for ovulation induction in women with polycystic ovarian syndrome: a prospective randomized trial. | Fertility and sterility 20090901 |
Letrozole versus clomiphene citrate: which is better for ovulation induction? | Fertility and sterility 20090901 |
Comparison of efficacy of aromatase inhibitor and clomiphene citrate in induction of ovulation in polycystic ovarian syndrome. | Fertility and sterility 20090901 |
Does confirmatory tumor biopsy alter the management of breast cancer patients with distant metastases? | Annals of oncology : official journal of the European Society for Medical Oncology 20090901 |
Bone fractures among postmenopausal patients with endocrine-responsive early breast cancer treated with 5 years of letrozole or tamoxifen in the BIG 1-98 trial. | Annals of oncology : official journal of the European Society for Medical Oncology 20090901 |
Aromatase inhibitor for treatment of a recurrent abdominal wall endometrioma in a postmenopausal woman. | Fertility and sterility 20090901 |
Subdural collections arising from calvarial metastases following discontinuation of anti-angiogenic therapy. | Annals of oncology : official journal of the European Society for Medical Oncology 20090901 |
Strategies for maximizing growth in puberty in children with short stature. | Endocrinology and metabolism clinics of North America 20090901 |
The role of neoadjuvant (HER)2-targeted therapies in (HER)2-overexpressing breast cancers. | Current oncology (Toronto, Ont.) 20090901 |
Effects of letrozole on bone biomarkers and femur fracture in female rats. | Journal of physiology and biochemistry 20090901 |
Long-term potentiation in the rat medial vestibular nuclei depends on locally synthesized 17beta-estradiol. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090826 |
Letrozole: a review of its use in the treatment of postmenopausal women with hormone-responsive early breast cancer. | Drugs 20090820 |
Letrozole therapy alone or in sequence with tamoxifen in women with breast cancer. | The New England journal of medicine 20090820 |
Can cutaneous telangiectasiae as late normal-tissue injury predict cardiovascular disease in women receiving radiotherapy for breast cancer? | British journal of cancer 20090804 |
Endometrial and follicular development following letrozole intervention in unexplained infertile patients failed to get pregnant with clomiphene citrate. | Archives of gynecology and obstetrics 20090801 |
Cholesterol-promoted synaptogenesis requires the conversion of cholesterol to estradiol in the hippocampus. | Hippocampus 20090801 |
Porcine hypothalamic aromatase cytochrome P450: isoform characterization, sex-dependent activity, regional expression, and regulation by enzyme inhibition in neonatal boars. | Biology of reproduction 20090801 |
Estrogen promotes germ cell and seminiferous tubule development in the baboon fetal testis. | Biology of reproduction 20090801 |
Alfacalcidol prevents aromatase inhibitor (Letrozole)-induced bone mineral loss in young growing female rats. | The Journal of endocrinology 20090801 |
Androgen- and estrogen-independent regulation of copulatory behavior following castration in male B6D2F1 mice. | Hormones and behavior 20090801 |
Estrogens regulate humans and rabbit epididymal contractility through the RhoA/Rho-kinase pathway. | The journal of sexual medicine 20090801 |
In vitro kinetic properties of the Thr201Met variant of human aromatase gene CYP19A1: functional responses to substrate and product inhibition and enzyme inhibitors. | The Journal of clinical endocrinology and metabolism 20090801 |
Use of the aromatase inhibitor letrozole to treat male infertility. | Fertility and sterility 20090801 |
Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer 2009. | Annals of oncology : official journal of the European Society for Medical Oncology 20090801 |
Fulvestrant treatment is associated with cholesterol plasma level reduction in hormone-receptor-positive metastatic breast cancer patients. | Cancer biology & therapy 20090801 |
The role of HER2-targeted therapies in women with HER2-overexpressing metastatic breast cancer. | Current oncology (Toronto, Ont.) 20090801 |
Clinical perspectives on the utility of aromatase inhibitors for the adjuvant treatment of breast cancer. | Breast (Edinburgh, Scotland) 20090801 |
De novo synthesis of estrogen in pregnant uterus is critical for stromal decidualization and angiogenesis. | Proceedings of the National Academy of Sciences of the United States of America 20090728 |
Antagonist/letrozole protocol in poor ovarian responders for intracytoplasmic sperm injection: a comparative study with the microdose flare-up protocol. | Fertility and sterility 20090701 |
Extended letrozole therapy for ovulation induction in clomiphene-resistant women with polycystic ovary syndrome: a novel protocol. | Fertility and sterility 20090701 |
Letrozole administration during the luteal phase after ovarian stimulation impacts corpus luteum function: a randomized, placebo-controlled trial. | Fertility and sterility 20090701 |
Aromatase expression and outcomes in the P024 neoadjuvant endocrine therapy trial. | Breast cancer research and treatment 20090701 |
Endocrine effects of adjuvant letrozole compared with tamoxifen in hormone-responsive postmenopausal patients with early breast cancer: the HOBOE trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090701 |
The Global Longitudinal Study of Osteoporosis in Women (GLOW): rationale and study design. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20090701 |
Reassurance of safety of letrozole and suggested approaches in controlled ovarian hyperstimulation. | Fertility and sterility 20090701 |
Promising effect of aromatase inhibitors on recurrent granulosa cell tumors. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20090701 |
Aromatase inhibitors for ovulation and pregnancy in polycystic ovary syndrome. | The Annals of pharmacotherapy 20090701 |
Letrozole as a booster therapy in growth hormone deficiency. | Indian pediatrics 20090701 |
An updated review on the efficacy of adjuvant endocrine therapies in hormone receptor-positive early breast cancer. | Current oncology (Toronto, Ont.) 20090701 |
Safety of adjuvant endocrine therapies in hormone receptor-positive early breast cancer. | Current oncology (Toronto, Ont.) 20090701 |
Preservation of fertility in patients with cancer. | The New England journal of medicine 20090618 |
High performance liquid chromatography method for the pharmacokinetic study of bicalutamide SMEDDS and suspension formulations after oral administration to rats. | Talanta 20090615 |
Effects of binary mixtures of estrogen and antiestrogens on Japanese medaka (Oryzias latipes). | Aquatic toxicology (Amsterdam, Netherlands) 20090604 |
Letrozole co-treatment in infertile women 40 years old and older receiving controlled ovarian stimulation and intrauterine insemination. | Fertility and sterility 20090601 |
Digital image analysis of breast epithelial cells collected by random periareolar fine-needle aspirates (RPFNA) from women at high risk for breast cancer taking hormone replacement and the aromatase inhibitor, letrozole, for six months. | Breast cancer research and treatment 20090601 |
Regulation of baboon fetal pituitary prolactin expression by estrogen. | Biology of reproduction 20090601 |
Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090601 |
History of aromatase: saga of an important biological mediator and therapeutic target. | Endocrine reviews 20090601 |
Comparative review of anastrozole, letrozole and exemestane in the management of early breast cancer. | Expert opinion on pharmacotherapy 20090601 |
Optimizing success with donor insemination. | Frontiers in bioscience (Elite edition) 20090601 |
Design, conduct, and analyses of Breast International Group (BIG) 1-98: a randomized, double-blind, phase-III study comparing letrozole and tamoxifen as adjuvant endocrine therapy for postmenopausal women with receptor-positive, early breast cancer. | Clinical trials (London, England) 20090601 |
Differential effects of aromatase inhibitors and antiestrogens on estrogen receptor expression in breast cancer cells. | Anticancer research 20090601 |
Enhancing the efficacy of hormonal agents with selected targeted agents. | Clinical breast cancer 20090601 |
A question of duration: do patients with early-stage breast cancer need more than five years of adjuvant endocrine therapy? | Clinical breast cancer 20090601 |
Knowledge discovery processing and data mining in karyometry. | Analytical and quantitative cytology and histology 20090601 |
Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer. | Journal of the National Cancer Institute 20090520 |
Letrozole stimulates the growth of human endometrial explants cultured in three-dimensional fibrin matrix. | Fertility and sterility 20090501 |
A woman's heart: the impact of adjuvant endocrine therapy on cardiovascular health. | Cancer 20090501 |
The efficacy of hormonal treatment for residual or recurrent low-grade endometrial stromal sarcoma. A retrospective study. | European journal of obstetrics, gynecology, and reproductive biology 20090501 |
Sustained effect of the aromatase inhibitors anastrozole and letrozole on endometrial thickness in patients with endometrial hyperplasia and endometrial carcinoma. | Current medical research and opinion 20090501 |
Zoledronic acid effectively prevents aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole: Z-FAST study 36-month follow-up results. | Clinical breast cancer 20090501 |
Accelerated cutaneous nodulosis associated with aromatase inhibitor therapy in a patient with rheumatoid arthritis. | The Journal of rheumatology 20090501 |
Improved surgical outcomes for breast cancer patients receiving neoadjuvant aromatase inhibitor therapy: results from a multicenter phase II trial. | Journal of the American College of Surgeons 20090501 |
2-Benzoylmethyl-4-[(2-benzylidene-ethylidene)amino]-5-(2-thienylmethyl)-2H-1,2,4-triazol-3(4H)-one. | Acta crystallographica. Section E, Structure reports online 20090501 |
4-[(E)-4-Methoxy-benzyl-ideneamino]-3-{1-[4-(2-methyl-prop-yl)phen-yl]eth-yl}-1H-1,2,4-triazole-5(4H)-thione. | Acta crystallographica. Section E, Structure reports online 20090501 |
A randomised study of the effects of letrozole and anastrozole on oestrogen receptor positive breast cancers in postmenopausal women. | Breast cancer research and treatment 20090401 |
Regression of chronic lymphocytic leukemia with aromatase inhibitor-letrozole? | Leukemia research 20090401 |
Aromatase inhibitors prevent the estrogen rise associated with the flare effect of gonadotropins in patients treated with GnRH agonists. | Fertility and sterility 20090401 |
Developmental regulation of the expression of the transferrin receptor and Ki67 in oocytes of the baboon fetal ovary by estrogen. | Endocrine 20090401 |
Successful treatment of refractory endometriosis-related chronic pelvic pain with aromatase inhibitors in premenopausal patients. | European journal of obstetrics, gynecology, and reproductive biology 20090401 |
Bone Quality Test (BQT) scores of fingernails in postmenopausal patients treated with adjuvant letrozole or tamoxifen for early breast cancer. | Breast (Edinburgh, Scotland) 20090401 |
Reinvestigation of the synthesis and evaluation of [N-methyl-(11)C]vorozole, a radiotracer targeting cytochrome P450 aromatase. | Nuclear medicine and biology 20090401 |
Gene expression profiles differentiating between breast cancers clinically responsive or resistant to letrozole. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090320 |
Effectiveness of a letter notification program for women with early-stage breast cancer eligible for extended adjuvant letrozole. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090320 |
Poor survival outcomes in HER2-positive breast cancer patients with low-grade, node-negative tumours. | British journal of cancer 20090310 |
Long-term effectiveness of adjuvant goserelin in premenopausal women with early breast cancer. | Journal of the National Cancer Institute 20090304 |
Endometrial effects of letrozole and clomiphene citrate in women with polycystic ovary syndrome using spiral artery Doppler. | Archives of gynecology and obstetrics 20090301 |
Short-term aromatase inhibition: effects on glucose metabolism and serum leptin levels in young and elderly men. | European journal of endocrinology 20090301 |
Lack of complete cross-resistance between different aromatase inhibitors; a real finding in search for an explanation? | European journal of cancer (Oxford, England : 1990) 20090301 |
Infusional fluorouracil, epirubicin, and cisplatin followed by weekly paclitaxel plus bevacizumab in locally advanced breast cancer with unfavorable prognostic features. | Anti-cancer drugs 20090301 |
Future targets in endometriosis treatment: targeting the endometriotic implant. | Mini reviews in medicinal chemistry 20090301 |
[Adjuvant breast cancer treatment with hormono-radiotherapy]. | Bulletin du cancer 20090301 |
[Lipid metabolism disorders at the breast cancer patients receiving hormonotherapy]. | Georgian medical news 20090301 |
Development of cell-cycle inhibitors for cancer therapy. | Current oncology (Toronto, Ont.) 20090301 |
Controversies in the definition and treatment of idiopathic short stature (ISS). | Journal of clinical research in pediatric endocrinology 20090301 |
3-[1-(4-Isobutyl-phen-yl)eth-yl]-1H-1,2,4-triazole-5(4H)-thione. | Acta crystallographica. Section E, Structure reports online 20090301 |
[Ovulation induction by means of letrozole]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20090226 |
Trastuzumab reverses letrozole resistance and amplifies the sensitivity of breast cancer cells to estrogen. | Cancer research 20090215 |
Exemestane as primary treatment of oestrogen receptor-positive breast cancer in postmenopausal women: a phase II trial. | British journal of cancer 20090210 |
Treating elderly patients with hormone sensitive breast cancer: what do the data show? | Cancer treatment reviews 20090201 |
A case of prolonged disease-free survival in a patient with choroidal metastasis from breast cancer. | Nature clinical practice. Oncology 20090201 |
Aromatase inhibitors and bone health. | Current opinion in obstetrics & gynecology 20090201 |
Rapid quantitative analysis of letrozole, fluoxetine and their metabolites in biological and environmental samples by MEKC. | Electrophoresis 20090201 |
Immunomodulation of FOXP3+ regulatory T cells by the aromatase inhibitor letrozole in breast cancer patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090201 |
Long-term inhibition of 5-alpha reductase and aromatase changes the cellular and extracellular compartments in gerbil ventral prostate at different postnatal ages. | International journal of experimental pathology 20090201 |
Synthesis and PET studies of [(11)C-cyano]letrozole (Femara), an aromatase inhibitor drug. | Nuclear medicine and biology 20090201 |
Phase 3 trials of aromatase inhibitors for breast cancer prevention: following in the path of the selective estrogen receptor modulators. | Annals of the New York Academy of Sciences 20090201 |
Aromatase inhibitors and breast cancer. | Annals of the New York Academy of Sciences 20090201 |
Phosphorylated ERalpha, HIF-1alpha, and MAPK signaling as predictors of primary endocrine treatment response and resistance in patients with breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090110 |
Fast three dimensional pharmacophore virtual screening of new potent non-steroid aromatase inhibitors. | Journal of medicinal chemistry 20090108 |
Joint effects of body size, energy intake, and physical activity on breast cancer risk. | Breast cancer research and treatment 20090101 |
Effects of letrozole and clomiphene citrate on the expression of HOXA10 and integrin alpha v beta 3 in uterine epithelium of rats. | Fertility and sterility 20090101 |
Increase in response rate by prolonged treatment with neoadjuvant letrozole. | Breast cancer research and treatment 20090101 |
Start strong or switch? Adjuvant endocrine strategies for postmenopausal women with hormone-sensitive breast cancer. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090101 |
Letrozole in ovulation induction: time to make decisions. | Human reproduction update 20090101 |
Prescribing adjuvant letrozole to patients well after the completion of tamoxifen: a good idea? | Current oncology reports 20090101 |
Pregnancy outcome after ovulation induction with aromatase inhibitors or clomiphene citrate in unexplained infertility. | Acta obstetricia et gynecologica Scandinavica 20090101 |
The Coffey Lecture: steroidogenic enzyme inhibitors and hormone dependent cancer. | Urologic oncology 20090101 |
San Antonio Breast Cancer Symposium. | The Lancet. Oncology 20090101 |
Vitamin D insufficiency and musculoskeletal symptoms in breast cancer survivors on aromatase inhibitor therapy. | Cancer nursing 20090101 |
Comparison of letrozole with continuous gonadotropins and clomiphene-gonadotropin combination for ovulation induction in 1387 PCOS women after clomiphene citrate failure: a randomized prospective clinical trial. | Journal of assisted reproduction and genetics 20090101 |
Update on the role of aromatase inhibitors in growth disorders. | Hormone research 20090101 |
A case of Meigs syndrome mimicking metastatic breast carcinoma. | World journal of surgical oncology 20090101 |
An ER activity profile including ER, PR, Bcl-2 and IGF-IR may have potential as selection criterion for letrozole or tamoxifen treatment of patients with advanced breast cancer. | Acta oncologica (Stockholm, Sweden) 20090101 |
Breast cancer in young women and its impact on reproductive function. | Human reproduction update 20090101 |
Current indications for post-mastectomy radiation. | International seminars in surgical oncology : ISSO 20090101 |
Are we HER-ting for innovation in neoadjuvant breast cancer trial design? | Breast cancer research : BCR 20090101 |
Development and validation of RP-HPLC method to determine letrozole in different pharmaceutical formulations and its application to studies of drug release from nanoparticles. | Acta poloniae pharmaceutica 20090101 |
Determination of HER2 phosphorylation at tyrosine 1221/1222 improves prediction of poor survival for breast cancer patients with hormone receptor-positive tumors. | Breast cancer research : BCR 20090101 |
Diagnosis and treatment of early breast cancer, including locally advanced disease--summary of NICE guidance. | BMJ (Clinical research ed.) 20090101 |
Risk reduction of distant metastasis in hormone-sensitive postmenopausal breast cancer. | Breast cancer (Tokyo, Japan) 20090101 |
Enhancing the adjuvant treatment of hormone receptor positive breast cancer. | The breast journal 20090101 |
Quantitative real-time RT-PCR and chromogenic in situ hybridization: precise methods to detect HER-2 status in breast carcinoma. | BMC cancer 20090101 |
Impact of aromatase inhibitor therapy on bone turnover, cortical bone growth and vertebral morphology in pre- and peripubertal boys with idiopathic short stature. | Hormone research 20090101 |
Australian clinicians and chemoprevention for women at high familial risk for breast cancer. | Hereditary cancer in clinical practice 20090101 |
A review of the use of exemestane in early breast cancer. | Therapeutics and clinical risk management 20090101 |
Comparison of subjective and objective hot flash measures over time among breast cancer survivors initiating aromatase inhibitor therapy. | Menopause (New York, N.Y.) 20090101 |
Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells. | BMC cancer 20090101 |
In situ aromatase expression in primary tumor is associated with estrogen receptor expression but is not predictive of response to endocrine therapy in advanced breast cancer. | BMC cancer 20090101 |
Extended adjuvant hormonal therapy with exemestane has no detrimental effect on the lipid profile of postmenopausal breast cancer patients: final results of the ATENA lipid substudy. | Breast cancer research : BCR 20090101 |
Current trends in the treatment of polycystic ovary syndrome with desire for children. | Therapeutics and clinical risk management 20090101 |
The Gene expression Grade Index: a potential predictor of relapse for endocrine-treated breast cancer patients in the BIG 1-98 trial. | BMC medical genomics 20090101 |
[Criteria for evaluating the effectiveness of aromatase inhibitors in the neoadjuvant treatment of patients with endometrial carcinoma]. | Voprosy onkologii 20090101 |
Pathologic and biologic response to preoperative endocrine therapy in patients with ER-positive ductal carcinoma in situ. | BMC cancer 20090101 |
Disruption in the expression and immunolocalisation of steroid receptors and steroidogenic enzymes in letrozole-induced polycystic ovaries in rat. | Reproduction, fertility, and development 20090101 |
HER2 breast cancer therapies: a review. | Biologics : targets & therapy 20090101 |
'hCG priming' effect in controlled ovarian stimulation through a long protocol. | Reproductive biology and endocrinology : RB&E 20090101 |
Recent advances in systemic therapy. When HER2 is not the target: advances in the treatment of HER2-negative metastatic breast cancer. | Breast cancer research : BCR 20090101 |
Tumor tissue levels of Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) and outcome following adjuvant chemotherapy in premenopausal lymph node-positive breast cancer patients: A retrospective study. | BMC cancer 20090101 |
Long-term efficacy and safety of anastrozole for adjuvant treatment of early breast cancer in postmenopausal women. | Therapeutics and clinical risk management 20090101 |
Long-term efficacy and safety of letrozole for the adjuvant treatment of early breast cancer in postmenopausal women: a review. | Therapeutics and clinical risk management 20090101 |
A novel variant of ER-alpha, ER-alpha36 mediates testosterone-stimulated ERK and Akt activation in endometrial cancer Hec1A cells. | Reproductive biology and endocrinology : RB&E 20090101 |
Drugs associated with more suicidal ideations are also associated with more suicide attempts. | PloS one 20090101 |
Phase I dose escalation pharmacokinetic assessment of intravenous humanized anti-MUC1 antibody AS1402 in patients with advanced breast cancer. | Breast cancer research : BCR 20090101 |
Abnormal 18F-FDG Uptake Detected with Positron Emission Tomography in a Patient with Breast Cancer: A Case of Sarcoidosis and Review of the Literature. | Case reports in medicine 20090101 |
Can survival prediction be improved by merging gene expression data sets? | PloS one 20090101 |
Targeting tumorigenesis: development and use of mTOR inhibitors in cancer therapy. | Journal of hematology & oncology 20090101 |
Pre-hCG 3D and 3D power Doppler assessment of the follicle for improving pregnancy rates in intrauterine insemination cycles. | Journal of human reproductive sciences 20090101 |
Continuous 5-fluorouracil infusion plus long acting octreotide in advanced well-differentiated neuroendocrine carcinomas. A phase II trial of the Piemonte oncology network. | BMC cancer 20090101 |
Update on the use of aromatase inhibitors in early-stage breast cancer. | Breast cancer research : BCR 20090101 |
Serum estradiol should be monitored not only during the peri-menopausal period but also the post-menopausal period at the time of aromatase inhibitor administration. | World journal of surgical oncology 20090101 |
Antiproliferative effect of exemestane in lung cancer cells. | Molecular cancer 20090101 |
Idiopathic short stature: conundrums of definition and treatment. | International journal of pediatric endocrinology 20090101 |
Drug-induced hematologic syndromes. | Advances in hematology 20090101 |
The potential use of intrauterine insemination as a basic option for infertility: a review for technology-limited medical settings. | Obstetrics and gynecology international 20090101 |
Who would have thought a single Ki67 measurement would predict long-term outcome? | Breast cancer research : BCR 20090101 |
Introduction to sessions on guidelines and endocrine therapy, the influence of breast screening on number of mastectomies and the challenge between molecular science and traditional dogma in the treatment of breast cancer. Introduction to Session 6. | Breast cancer research : BCR 20090101 |
Do BIG1-98 and ZOFAST demand a change in guidelines for endocrine therapy? | Breast cancer research : BCR 20090101 |
Breast screening has increased the number of mastectomies. | Breast cancer research : BCR 20090101 |
Are current drug development programmes realising the full potential of new agents? The scenario. | Breast cancer research : BCR 20090101 |
Are current drug development programmes realising the full potential of new agents? Tyrosine kinase inhibitors. | Breast cancer research : BCR 20090101 |
Controversies in breast cancer: the mammalian target of rapamycin as a target for breast cancer therapy. | Breast cancer research : BCR 20090101 |
Tailored targeted therapy for all: a realistic and worthwhile objective? | Breast cancer research : BCR 20090101 |
CDK inhibitors as potential breast cancer therapeutics: new evidence for enhanced efficacy in ER+ disease. | Breast cancer research : BCR 20090101 |
[Aromatase inhibitors in risk reduction of breast cancer: potential use in premenopausal women]. | Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20090101 |
Role of neo-adjuvant hormonal therapy in the treatment of breast cancer: a review of clinical trials. | International journal of general medicine 20090101 |
The evolving role of zoledronic acid in early breast cancer. | OncoTargets and therapy 20090101 |
Multiple roles and therapeutic implications of Akt signaling in cancer. | OncoTargets and therapy 20090101 |
Acute uveitis following zoledronic acid infusion. | Oman journal of ophthalmology 20090101 |
Recent advances in managing osteoporosis. | F1000 medicine reports 20090101 |
Aromatase inhibitor strategies in metastatic breast cancer. | International journal of women's health 20090101 |
Growth factor receptors and apoptosis regulators: signaling pathways, prognosis, chemosensitivity and treatment outcomes of breast cancer. | Breast cancer : basic and clinical research 20090101 |
The evolution of treatment for early breast cancer: what's next? | Ecancermedicalscience 20090101 |
Sonographic evaluation of endothelial function in letrozole and tamoxifen users. | Maturitas 20081220 |
Economic evaluation of fulvestrant as an extra step in the treatment sequence for ER-positive advanced breast cancer. | British journal of cancer 20081209 |
Reducing endogenous estrogens during the neonatal and juvenile periods affects reproductive tract development and sperm production in postpuberal boars. | Animal reproduction science 20081201 |
Preoperative concurrent chemo- and endocrine therapies for women with large operable breast cancer expressing steroid hormone receptors. | Breast (Edinburgh, Scotland) 20081201 |
Abnormal cervical smear: a sign of disseminated breast cancer. | European journal of obstetrics, gynecology, and reproductive biology 20081201 |
Extending the benefits of adjuvant therapy in early HR+ breast cancer. | Breast cancer research and treatment 20081201 |
Never too late: reducing late breast cancer relapse risk. | Current medical research and opinion 20081201 |
Prognostic and predictive value of centrally reviewed Ki-67 labeling index in postmenopausal women with endocrine-responsive breast cancer: results from Breast International Group Trial 1-98 comparing adjuvant tamoxifen with letrozole. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081201 |
Overcoming recurrence risk: extended adjuvant endocrine therapy. | Clinical breast cancer 20081201 |
Understanding the BIG results: Insights from the BIG 1-98 trial analyses. | Advances in therapy 20081201 |
Are all aromatase inhibitors alike? | Breast cancer research and treatment 20081201 |
Aromatase inhibitors, efficacy and metabolic risk in the treatment of postmenopausal women with early breast cancer. | Clinical interventions in aging 20081201 |
Exemestane in early breast cancer: a review. | Therapeutics and clinical risk management 20081201 |
3-[1-(4-Isobutyl-phen-yl)eth-yl]-4-[(E)-4-methyl-benzyl-ideneamino]-1H-1,2,4-triazole-5(4H)-thione. | Acta crystallographica. Section E, Structure reports online 20081201 |
Preoperative bevacizumab combined with letrozole and chemotherapy in locally advanced ER- and/or PgR-positive breast cancer: clinical and biological activity. | British journal of cancer 20081104 |
Effect of letrozole at 2.5 mg or 5.0 mg/day on ovarian stimulation with gonadotropins in women undergoing intrauterine insemination. | Fertility and sterility 20081101 |
Aromatase inhibitors in the management of early breast cancer. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20081101 |
Dietary genistein negates the inhibitory effect of letrozole on the growth of aromatase-expressing estrogen-dependent human breast cancer cells (MCF-7Ca) in vivo. | Carcinogenesis 20081101 |
Aromatase inhibition during adolescence reduces adult sexual and paternal behavior in the biparental dwarf hamster Phodopus campbelli. | Hormones and behavior 20081101 |
[Effect of two different doses of letrozole in promoting ovulation in infertile women with polycystic ovarian syndrome]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20081101 |
[Problems and future direction of preoperative systemic therapy for patients with operable breast cancer]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20081101 |
A new therapeutic strategy against hormone-dependent breast cancer: the preclinical development of a dual aromatase and sulfatase inhibitor. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081015 |
A comparison of letrozole to gonadotropins for ovulation induction in subjects with advanced maternal age: a retrospective pilot study. | Fertility and sterility 20081001 |
Antiestrogen therapies affect tissue homeostasis of the gerbil (Meriones unguiculatus) female prostate and ovaries. | Biology of reproduction 20081001 |
Effects of testosterone undecanoate administered alone or in combination with letrozole or dutasteride in female to male transsexuals. | The journal of sexual medicine 20081001 |
Cutaneous vasculitis in breast cancer treated with chemotherapy. | Clinical immunology (Orlando, Fla.) 20081001 |
Focus on breast and ovarian cancer. | Placenta 20081001 |
HER-2-positive metastatic breast cancer: trastuzumab and beyond. | Expert opinion on pharmacotherapy 20081001 |
Outcome prediction for estrogen receptor-positive breast cancer based on postneoadjuvant endocrine therapy tumor characteristics. | Journal of the National Cancer Institute 20081001 |
Letrozole is superior to anastrozole in suppressing breast cancer tissue and plasma estrogen levels. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081001 |
Treatment of symptomatic uterine leiomyoma with letrozole. | Reproductive biomedicine online 20081001 |
Safety profiles of aromatase inhibitors and selective estrogen-receptor modulators in the treatment of early breast cancer. | International journal of clinical oncology 20081001 |
Extended adjuvant endocrine therapy in breast cancer: current status and future directions. | Clinical breast cancer 20081001 |
Breast cancer survivors. | Australian family physician 20081001 |
Survival from breast cancer in England and Wales up to 2001. | British journal of cancer 20080923 |
Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential? | British journal of cancer 20080902 |
Prospective characterization of musculoskeletal symptoms in early stage breast cancer patients treated with aromatase inhibitors. | Breast cancer research and treatment 20080901 |
Randomized controlled trial comparing superovulation with letrozole versus recombinant follicle-stimulating hormone combined with intrauterine insemination for couples with unexplained infertility who had failed clomiphene citrate stimulation and intrauterine insemination. | Fertility and sterility 20080901 |
Screening and management of osteoporosis in breast cancer patients on aromatase inhibitors. | Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20080901 |
Luteal phase oestradiol suppression by letrozole: a pilot study in oocyte donors. | Reproductive biomedicine online 20080901 |
Hormone therapy for epithelial ovarian cancer. | Current opinion in oncology 20080901 |
Synthesis of 6- or 4-functionalized indoles via a reductive cyclization approach and evaluation as aromatase inhibitors. | Bioorganic & medicinal chemistry letters 20080815 |
Target and reality of adjuvant endocrine therapy in postmenopausal patients with invasive breast cancer. | British journal of cancer 20080805 |
Safely promoting breast-conserving surgery and preventing early relapses with an aromatase inhibitor. | Surgical oncology 20080801 |
Tolerance of adjuvant letrozole outside of clinical trials. | Breast (Edinburgh, Scotland) 20080801 |
Effects of the aromatase inhibitor letrozole on in utero development in rats. | Human reproduction (Oxford, England) 20080801 |
Reducing early recurrence with adjuvant aromatase inhibitors: what is the evidence? | Breast (Edinburgh, Scotland) 20080801 |
The endocrine prevention of breast cancer. | Best practice & research. Clinical endocrinology & metabolism 20080801 |
[Clinical analysis of assistant treatment proposals for infertile women with polycystic ovary syndrome]. | Zhonghua fu chan ke za zhi 20080801 |
4-[(E)-2-Furylmethyl-eneamino]-3-phenyl-1H-1,2,4-triazole-5(4H)-thione. | Acta crystallographica. Section E, Structure reports online 20080801 |
Chiral aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole template: synthesis, absolute configuration, and in vitro activity. | Journal of medicinal chemistry 20080724 |
MCF-7aro/ERE, a novel cell line for rapid screening of aromatase inhibitors, ERalpha ligands and ERRalpha ligands. | Biochemical pharmacology 20080715 |
A phase I and pharmacokinetic study of lapatinib in combination with letrozole in patients with advanced cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080715 |
The impact of adjuvant therapy on contralateral breast cancer risk and the prognostic significance of contralateral breast cancer: a population based study in the Netherlands. | Breast cancer research and treatment 20080701 |
A phase II, randomized, blinded study of the farnesyltransferase inhibitor tipifarnib combined with letrozole in the treatment of advanced breast cancer after antiestrogen therapy. | Breast cancer research and treatment 20080701 |
Effectiveness of cetrorelix for the prevention of premature luteinizing hormone surge during controlled ovarian stimulation using letrozole and gonadotropins: a randomized trial. | Fertility and sterility 20080701 |
Choosing early adjuvant therapy for postmenopausal women with hormone-sensitive breast cancer: aromatase inhibitors versus tamoxifen. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20080701 |
The role of endocrine therapies in reducing risk of recurrence in postmenopausal women with hormone receptor-positive breast cancer. | European journal of oncology nursing : the official journal of European Oncology Nursing Society 20080701 |
Efficacy of letrozole in the treatment of recurrent platinum- and taxane-resistant high-grade cancer of the ovary or peritoneum. | Gynecologic oncology 20080701 |
Celecoxib anti-aromatase neoadjuvant (CAAN) trial for locally advanced breast cancer. | The Journal of steroid biochemistry and molecular biology 20080701 |
Xanthones from the botanical dietary supplement mangosteen (Garcinia mangostana) with aromatase inhibitory activity. | Journal of natural products 20080701 |
Method to test whether late extended letrozole, rather than self- selection, improves the outcome in patients with breast cancer who have completed 5 years of tamoxifen. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080701 |
Experience with exemestane in the treatment of early and advanced breast cancer. | Expert opinion on drug metabolism & toxicology 20080701 |
Stopping treatment can reverse acquired resistance to letrozole. | Cancer research 20080615 |
Genome-wide analysis of aromatase inhibitor-resistant, tamoxifen-resistant, and long-term estrogen-deprived cells reveals a role for estrogen receptor. | Cancer research 20080615 |
Factors that predict early treatment failure for patients with locally advanced (T4) breast cancer. | British journal of cancer 20080603 |
Increased intrafollicular androgen levels affect human granulosa cell secretion of anti-Müllerian hormone and inhibin-B. | Fertility and sterility 20080601 |
Pre-clinical validation of early molecular markers of sensitivity to aromatase inhibitors in a mouse model of post-menopausal hormone-sensitive breast cancer. | Breast cancer research and treatment 20080601 |
Intravenous leiomyomatosis treated with aromatase inhibitor therapy. | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20080601 |
Serum TIMP-1 and response to the aromatase inhibitor letrozole versus tamoxifen in metastatic breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080601 |
Excellent response to letrozole in brain metastases from breast cancer. | Acta neurochirurgica 20080601 |
Fertility preservation: a vital survivorship issue for young women with breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080601 |
Safety of fertility preservation by ovarian stimulation with letrozole and gonadotropins in patients with breast cancer: a prospective controlled study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080601 |
Drugs in infertility and fetal safety. | Fertility and sterility 20080601 |
Estrogen receptor (ER) and epidermal growth factor receptor (EGFR) as targets for dual lung cancer therapy: not just a case? | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080601 |
Aromatase inhibitors: a new reality for the adjuvant endocrine treatment of early-stage breast cancer in postmenopausal women. | Mini reviews in medicinal chemistry 20080601 |
Dimethandrolone (7alpha,11beta-dimethyl-19-nortestosterone) and 11beta-methyl-19-nortestosterone are not converted to aromatic A-ring products in the presence of recombinant human aromatase. | The Journal of steroid biochemistry and molecular biology 20080601 |
Reducing the risk of distant metastases: a better end point in adjuvant aromatase inhibitor breast cancer trials? | Cancer investigation 20080601 |
[Adjuvant endocrine therapy in postmenopausal hormone-sensitive breast cancer: to start, to switch or to extend?]. | Magyar onkologia 20080601 |
Switching to letrozole or exemestane improves hot flushes, mood and quality of life in tamoxifen intolerant women. | British journal of cancer 20080506 |
Cost utility analysis of early adjuvant letrozole or anastrozole versus tamoxifen in postmenopausal women with early invasive breast cancer: the UK perspective. | The European journal of health economics : HEPAC : health economics in prevention and care 20080501 |
Anastrozole or letrozole for ovulation induction in clomiphene-resistant women with polycystic ovarian syndrome: a prospective randomized trial. | Fertility and sterility 20080501 |
Effects of letrozole on proliferation and apoptosis in cultured leiomyoma cells treated with prostaglandin E(2). | European journal of obstetrics, gynecology, and reproductive biology 20080501 |
CYP1B1 is not a major determinant of the disposition of aromatase inhibitors in epithelial cells of invasive ductal carcinoma. | Drug metabolism and disposition: the biological fate of chemicals 20080501 |
Sex steroids and leptin regulate the 'first Kiss' (KiSS 1/G-protein-coupled receptor 54 system) in human gonadotropin-releasing-hormone-secreting neuroblasts. | The journal of sexual medicine 20080501 |
Intent-to-treat analysis of the placebo-controlled trial of letrozole for extended adjuvant therapy in early breast cancer: NCIC CTG MA.17. | Annals of oncology : official journal of the European Society for Medical Oncology 20080501 |
Letrozole once a week normalizes serum testosterone in obesity-related male hypogonadism. | European journal of endocrinology 20080501 |
Comparison of the efficacy of the aromatase inhibitor letrozole and clomiphen citrate gonadotropins in controlled ovarian hyperstimulation: a prospective, simply randomized, clinical trial. | Journal of assisted reproduction and genetics 20080501 |
Down-regulation of phosphatidylinositol 3'-kinase/AKT/molecular target of rapamycin metabolic pathway by primary letrozole-based therapy in human breast cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080501 |
Targeting breast cancer with hormonal treatment options. | The Nurse practitioner 20080501 |
Controlling for the EFFECTS related to the underlying pathology of infertility. | Fertility and sterility 20080501 |
Integrated analysis of zoledronic acid for prevention of aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole. | The oncologist 20080501 |
Development, physical characterization, micromeritics and in vitro release kinetics of letrozole loaded biodegradable nanoparticles. | Die Pharmazie 20080501 |
Role of ErbB2 in selection for adjuvant tamoxifen or aromatase inhibitors. | Women's health (London, England) 20080501 |
Letrozole compared with tamoxifen for elderly patients with endocrine-responsive early breast cancer: the BIG 1-98 trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080420 |
Benefit from exemestane as extended adjuvant therapy after 5 years of adjuvant tamoxifen: intention-to-treat analysis of the National Surgical Adjuvant Breast And Bowel Project B-33 trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080420 |
Efficacy, toxicity, and quality of life in older women with early-stage breast cancer treated with letrozole or placebo after 5 years of tamoxifen: NCIC CTG intergroup trial MA.17. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080420 |
Late extended adjuvant treatment with letrozole improves outcome in women with early-stage breast cancer who complete 5 years of tamoxifen. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080420 |
Evaluation of neoadjuvant inhibition of aromatase activity and signal transduction in breast cancer. | Cancer letters 20080418 |
Cost-effectiveness of letrozole versus tamoxifen as initial adjuvant therapy in postmenopausal women with hormone-receptor positive early breast cancer from a Canadian perspective. | Breast cancer research and treatment 20080401 |
Beyond tamoxifen: extended and late extended endocrine therapy in postmenopausal early breast cancer. | Cancer treatment reviews 20080401 |
Aromatase inhibitors in adjuvant therapy for hormone receptor positive breast cancer: a systematic review. | Cancer treatment reviews 20080401 |
Aromatase inhibitors in early breast-cancer treatment: The story so far. | Breast (Edinburgh, Scotland) 20080401 |
Letrozole suppresses plasma estradiol and estrone sulphate more completely than anastrozole in postmenopausal women with breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080401 |
Impact of estrogen deprivation on gene expression profiles of normal postmenopausal breast tissue in vivo. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080401 |
[A case of elderly breast cancer achieving partial response by letrozole with stable disease to anastrozole as neoadjuvant endocrine therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080401 |
Neoadjuvant endocrine therapy for breast cancer: past, present and future. | Anti-cancer drugs 20080401 |
Micellar electrokinetic chromatographic method for the determination of letrozole, citalopram and their metabolites in human urine. | Journal of chromatography. A 20080328 |
Decision making in adjuvant trials in breast cancer: the NCIC CTG MA.17 trial as an example. | Breast cancer research and treatment 20080301 |
Facilitating breast-conserving surgery and preventing recurrence: aromatase inhibitors in the neoadjuvant and adjuvant settings. | Annals of surgical oncology 20080301 |
Effective inhibition of aromatase inhibitor-associated bone loss by zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole: ZO-FAST Study results. | Cancer 20080301 |
Aromatase inhibitors for breast cancer: different structures, same effects? | Endocrine-related cancer 20080301 |
Menopausal symptoms and adjuvant therapy-associated adverse events. | Endocrine-related cancer 20080301 |
Anticancer therapy in patients with porphyrias: evidence today. | Expert opinion on drug safety 20080301 |
A comparison of the effects of clomiphene citrate and the aromatase inhibitor letrozole on superovulation in Asian women with normal ovulatory cycles. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20080301 |
Is the use of letrozole to induce ovulation teratogenic? | Canadian family physician Medecin de famille canadien 20080301 |
Controversies in endocrine treatment: effective utilization of steroidal and nonsteroidal aromatase inhibitors: now and in the future. Forward. | Anti-cancer drugs 20080301 |
[The effect of hormone therapy on cognitive function in patients with breast cancer]. | Nederlands tijdschrift voor geneeskunde 20080301 |
Lapatinib in combination with capecitabine in the management of ErbB2-positive (HER2-positive) advanced breast cancer. | Biologics : targets & therapy 20080301 |
Time to remove the subspecialty blinders: breast cancer does not exist in isolation. | Journal of the National Cancer Institute 20080220 |
Competing causes of death from a randomized trial of extended adjuvant endocrine therapy for breast cancer. | Journal of the National Cancer Institute 20080220 |
Selective regulation of neurosteroid biosynthesis in human neuroblastoma cells under hydrogen peroxide-induced oxidative stress condition. | Neuroscience 20080206 |
Expression of lactoferrin in the boar epididymis: effects of reduced estrogen. | Domestic animal endocrinology 20080201 |
Gonadal steroid hormones maintain the stress-induced acetylcholine release in the hippocampus: simultaneous measurements of the extracellular acetylcholine and serum corticosterone levels in the same subjects. | Endocrinology 20080201 |
New 7,8-benzoflavanones as potent aromatase inhibitors: synthesis and biological evaluation. | Bioorganic & medicinal chemistry 20080201 |
Predicting response and resistance to endocrine therapy: profiling patients on aromatase inhibitors. | Cancer 20080201 |
Preclinical modeling of endocrine response and resistance: focus on aromatase inhibitors. | Cancer 20080201 |
Current NCI-sponsored Cooperative Group trials of endocrine therapies in breast cancer. | Cancer 20080201 |
Micellar electrokinetic chromatographic screening of letrozole and its metabolite in human urine: validation and robustness/ruggedness evaluation. | Electrophoresis 20080201 |
A single-nucleotide polymorphism in the aromatase gene is associated with the efficacy of the aromatase inhibitor letrozole in advanced breast carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080201 |
Ovulation induction in polycystic ovary syndrome. | Minerva ginecologica 20080201 |
Aromatase inhibitors for breast cancer: proven efficacy across the spectrum of disease. | Clinical breast cancer 20080201 |
Letrozole versus letrozole plus Lapatinib (GW572016) in hormone-sensitive, HER2-negative operable breast cancer: a double-blind, randomized, phase II study with biomarker evaluation (EGF109077-LAP107692/LETLOB). | Clinical breast cancer 20080201 |
Long-term safety of aromatase inhibitors in the treatment of breast cancer. | Therapeutics and clinical risk management 20080201 |
Endocrine effects of adjuvant letrozole + triptorelin compared with tamoxifen + triptorelin in premenopausal patients with early breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080110 |
Pharmacokinetics of raloxifene in male Wistar-Hannover rats: influence of complexation with hydroxybutenyl-beta-cyclodextrin. | International journal of pharmaceutics 20080104 |
Effects of letrozole on hippocampal and cortical catecholaminergic neurotransmitter levels, neural cell adhesion molecule expression and spatial learning and memory in female rats. | Neuroscience 20080102 |
Reducing endogenous estrogen during development alters hormone production by porcine Leydig cells and seminiferous tubules. | Domestic animal endocrinology 20080101 |
Management of poor responders: can outcomes be improved with a novel gonadotropin-releasing hormone antagonist/letrozole protocol? | Fertility and sterility 20080101 |
In vitro maturation of germinal vesicle oocytes recovered after premature luteinizing hormone surge: description of a novel approach to fertility preservation. | Fertility and sterility 20080101 |
The breast cancer continuum in hormone-receptor-positive breast cancer in postmenopausal women: evolving management options focusing on aromatase inhibitors. | Annals of oncology : official journal of the European Society for Medical Oncology 20080101 |
Letrozole as primary therapy for endometrial hyperplasia in young women. | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20080101 |
Increasing protection after tamoxifen: insights from the extended adjuvant aromatase inhibitor trials. | Journal of cancer research and clinical oncology 20080101 |
Aromatase inhibitors: past, present and future in breast cancer therapy. | Medical oncology (Northwood, London, England) 20080101 |
The oral mTOR inhibitor RAD001 (everolimus) in combination with letrozole in patients with advanced breast cancer: results of a phase I study with pharmacokinetics. | European journal of cancer (Oxford, England : 1990) 20080101 |
Adjuvant letrozole versus tamoxifen according to centrally-assessed ERBB2 status for postmenopausal women with endocrine-responsive early breast cancer: supplementary results from the BIG 1-98 randomised trial. | The Lancet. Oncology 20080101 |
San Antonio Breast Cancer Symposium. | The Lancet. Oncology 20080101 |
Preventive effects of letrozole in the model of premenopausal mammary carcinogenesis. | Neoplasma 20080101 |
Aromatase inhibitors: from bench to bedside and back. | Breast cancer (Tokyo, Japan) 20080101 |
Matters of the heart: cardiac toxicity of adjuvant systemic therapy for early-stage breast cancer. | Current oncology (Toronto, Ont.) 20080101 |
Cancer treatment-related bone loss: a review and synthesis of the literature. | Current oncology (Toronto, Ont.) 20080101 |
Training community resource center and clinic personnel to prompt patients in listing questions for doctors: follow-up interviews about barriers and facilitators to the implementation of consultation planning. | Implementation science : IS 20080101 |
Inhibition of vascular inflammation by dehydroepiandrosterone sulfate in human aortic endothelial cells: roles of PPARalpha and NF-kappaB. | Vascular pharmacology 20080101 |
The impact of adjuvant endocrine therapy on reducing the risk of distant metastases in hormone-responsive breast cancer. | Breast (Edinburgh, Scotland) 20080101 |
A review of the BIG results: the Breast International Group 1-98 trial analyses. | Breast (Edinburgh, Scotland) 20080101 |
Neoadjuvant letrozole in postmenopausal estrogen and/or progesterone receptor positive breast cancer: a phase IIb/III trial to investigate optimal duration of preoperative endocrine therapy. | BMC cancer 20080101 |
Joint one-sided and two-sided simultaneous confidence intervals. | Journal of biopharmaceutical statistics 20080101 |
[Adjuvant treatment of operable breast cancer]. | Anales de medicina interna (Madrid, Spain : 1984) 20080101 |
Breast conserving surgery with preservation of the nipple-areola complex as a feasible and safe approach in male breast cancer: a case report. | Journal of medical case reports 20080101 |
Aromatase inhibitors and mammographic breast density in postmenopausal women receiving hormone therapy. | Menopause (New York, N.Y.) 20080101 |
McCune-Albright syndrome. | Orphanet journal of rare diseases 20080101 |
Cancer and fertility preservation: fertility preservation in breast cancer patients. | Breast cancer research : BCR 20080101 |
Soy isoflavones, estrogen therapy, and breast cancer risk: analysis and commentary. | Nutrition journal 20080101 |
Evaluation of the quality and accuracy of information regarding aromatase inhibitors available on the internet. | The breast journal 20080101 |
Effects of maternal exposure to an aromatase inhibitor on sexual behaviour and neurochemical and endocrine aspects of adult male rat. | Reproduction, fertility, and development 20080101 |
The aromatase inhibitor letrozole and inhibitors of insulin-like growth factor I receptor synergistically induce apoptosis in in vitro models of estrogen-dependent breast cancer. | Breast cancer research : BCR 20080101 |
Co-occurrence of atypical endometriosis, subserous uterine leiomyomata, sactosalpinx, serous cystadenoma and bilateral hemorrhagic corpora lutea in a perimenopausal adipose patient taking tamoxifen (20 mg/day) for invasive lobular breast cancer. | Gynecologic and obstetric investigation 20080101 |
New steroidal aromatase inhibitors: suppression of estrogen-dependent breast cancer cell proliferation and induction of cell death. | BMC cell biology 20080101 |
Molecular targeted therapies for breast cancer treatment. | Breast cancer research : BCR 20080101 |
Enrichment with anti-cytokeratin alone or combined with anti-EpCAM antibodies significantly increases the sensitivity for circulating tumor cell detection in metastatic breast cancer patients. | Breast cancer research : BCR 20080101 |
Factors predictive of response to hormone therapy in breast cancer. | Tumori 20080101 |
Health-related quality of life in breast cancer patients: a bibliographic review of the literature from 1974 to 2007. | Journal of experimental & clinical cancer research : CR 20080101 |
ERalpha-status of disseminated tumour cells in bone marrow of primary breast cancer patients. | Breast cancer research : BCR 20080101 |
Bioequivalence study of two letrozole tablet formulations. Single dose, randomized, open-label, two-way crossover bioequivalence study of letrozole 2.5 mg tablets in healthy volunteers under fasting conditions. | Arzneimittel-Forschung 20080101 |
Current topics and perspectives on the use of aromatase inhibitors in the treatment of breast cancer. | Breast cancer (Tokyo, Japan) 20080101 |
Use of letrozole in assisted reproduction: a systematic review and meta-analysis. | Human reproduction update 20080101 |
Infertility and the provision of infertility medical services in developing countries. | Human reproduction update 20080101 |
Role of endocrine responsiveness and HER2/neu overexpression in inflammatory breast cancer treated with multimodality preoperative therapy. | The breast journal 20080101 |
Presentation and course of brain metastases from breast cancer in a paranoid-schizophrenic patient: A case report. | Cases journal 20080101 |
Novel therapies in breast cancer: what is new from ASCO 2008. | Journal of hematology & oncology 20080101 |
Redefining prognostic factors for breast cancer: YB-1 is a stronger predictor of relapse and disease-specific survival than estrogen receptor or HER-2 across all tumor subtypes. | Breast cancer research : BCR 20080101 |
Novel image analysis approach for quantifying expression of nuclear proteins assessed by immunohistochemistry: application to measurement of oestrogen and progesterone receptor levels in breast cancer. | Breast cancer research : BCR 20080101 |
Breast cancer in men: should aromatase inhibitors become first-line hormonal treatment? | The breast journal 20080101 |
Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature. | BMC cancer 20080101 |
Breast carcinoma metastatic to the orbit: an unusually late presentation. | Ophthalmic plastic and reconstructive surgery 20080101 |
Anti-oestrogens but not oestrogen deprivation promote cellular invasion in intercellular adhesion-deficient breast cancer cells. | Breast cancer research : BCR 20080101 |
Putative growth characteristics of micrometastatic breast cancer. | Breast cancer research : BCR 20080101 |
Genetic counselling and testing for inherited gene mutations in newly diagnosed patients with breast cancer: a review of the existing literature and a proposed research agenda. | Breast cancer research : BCR 20080101 |
Pharmacogenetics and pharmacogenomics of endocrine agents for breast cancer. | Breast cancer research : BCR 20080101 |
Markers of endocrine sensitivity. | Breast cancer research : BCR 20080101 |
Identification and mechanisms of endocrine resistance. | Breast cancer research : BCR 20080101 |
Integration of endocrine therapy with targeted agents. | Breast cancer research : BCR 20080101 |
Who should participate in clinical trials and who not? Can clinical trials be made more efficient and effective? | Breast cancer research : BCR 20080101 |
Neoadjuvant/presurgical treatments. | Breast cancer research : BCR 20080101 |
Polycystic ovaries and infertility: Our experience. | Journal of human reproductive sciences 20080101 |
Micellar electrokinetic chromatographic study of the separation of an aromatase inhibitor and a tryciclic antidepressant in the breast cancer treatment. | Analytical chemistry insights 20080101 |
Reverse phase high performance liquid chromatographic method for the analysis of letrozole in pharmaceutical dosage forms. | Indian journal of pharmaceutical sciences 20080101 |
The epidermal growth factor receptor family in breast cancer. | OncoTargets and therapy 20080101 |
Targeted treatment of advanced and metastaticbreast cancer with lapatinib. | OncoTargets and therapy 20080101 |
Cancer care in Singapore. | Biomedical imaging and intervention journal 20080101 |
Response of cutaneous metastases from breast cancer to capecitabine. | Clinical medicine. Oncology 20080101 |
Psychological Distress among Prostate Cancer Patients: Fact Or Fiction? | Clinical medicine. Oncology 20080101 |
Cardiovascular adverse events during adjuvant endocrine therapy for early breast cancer using letrozole or tamoxifen: safety analysis of BIG 1-98 trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071220 |
Extended adjuvant therapy with anastrozole among postmenopausal breast cancer patients: results from the randomized Austrian Breast and Colorectal Cancer Study Group Trial 6a. | Journal of the National Cancer Institute 20071219 |
Ontogeny of androgen and estrogen receptor expression in porcine testis: effect of reducing testicular estrogen synthesis. | Animal reproduction science 20071201 |
Treatment strategies that effectively reduce early recurrence risk in postmenopausal women with endocrine-sensitive breast cancer: AIs upfront vs. switching. | Journal of cancer research and clinical oncology 20071201 |
Effect of letrozole on urinary bladder function in the female rabbit. | BJU international 20071201 |
Reducing the risk of distant metastases in breast cancer patients: role of aromatase inhibitors. | Cancer treatment reviews 20071201 |
The what, why and how of aromatase inhibitors: hormonal agents for treatment and prevention of breast cancer. | International journal of clinical practice 20071201 |
Erythema nodosum secondary to aromatase inhibitor use in breast cancer patients: case reports and review of the literature. | Breast cancer research and treatment 20071201 |
Adjuvant and extended adjuvant use of aromatase inhibitors: reducing the risk of recurrence and distant metastasis. | Breast (Edinburgh, Scotland) 20071201 |
Reducing the risk of cancer treatment-associated bone loss in patients with breast cancer. | Seminars in oncology 20071201 |
Management of arthralgias associated with aromatase inhibitor therapy. | Current oncology (Toronto, Ont.) 20071201 |
Management of sexual dysfunction in postmenopausal breast cancer patients taking adjuvant aromatase inhibitor therapy. | Current oncology (Toronto, Ont.) 20071201 |
Cancer therapy disparity: unequal access to breast cancer therapeutics and drug funding in Canada. | Current oncology (Toronto, Ont.) 20071201 |
Managing bone loss in women with early-stage breast cancer receiving aromatase inhibitors. | Clinical breast cancer 20071201 |
Alteration of glyoxalase genes expression in response to testosterone in LNCaP and PC3 human prostate cancer cells. | Cancer biology & therapy 20071201 |
High circulating HER2 extracellular domain levels correlate with reduced efficacy of an aromatase inhibitor in hormone receptor-positive metastatic breast cancer: a confirmatory prospective study. | Cancer 20071115 |
Reduction in proliferation with six months of letrozole in women on hormone replacement therapy. | Breast cancer research and treatment 20071101 |
Management of cancer treatment-induced bone loss in early breast and prostate cancer -- a consensus paper of the Belgian Bone Club. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20071101 |
Novel therapeutic strategies combining antihormonal and biological targeted therapies in breast cancer: focus on clinical trials and perspectives. | Critical reviews in oncology/hematology 20071101 |
The use of third-generation aromatase inhibitors and tamoxifen in the adjuvant treatment of postmenopausal patients with hormone-dependent breast cancer: evidence based review. | Current opinion in oncology 20071101 |
Phase III, double-blind, controlled trial of atamestane plus toremifene compared with letrozole in postmenopausal women with advanced receptor-positive breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071101 |
Progression of endocrine therapies for breast cancer: where are we headed? | Expert review of anticancer therapy 20071101 |
Effects of third generation aromatase inhibitors on bone health and other safety parameters: results of an open, randomised, multi-centre study of letrozole, exemestane and anastrozole in healthy postmenopausal women. | European journal of cancer (Oxford, England : 1990) 20071101 |
Letrozole in advanced breast cancer: the PO25 trial. | Breast cancer research and treatment 20071001 |
Progesterone, but not luteal estrogen, is required for the establishment of pregnancy in the new world monkey Cebus apella. | American journal of primatology 20071001 |
Patients' knowledge and experience of adjuvant endocrine therapy for early breast cancer: a European study. | Breast (Edinburgh, Scotland) 20071001 |
Limiting access to letrozole--is it justified? | Fertility and sterility 20071001 |
Prescribing extended adjuvant letrozole. | Breast (Edinburgh, Scotland) 20071001 |
Estrogen is not essential for full endometrial restoration after breakdown: lessons from a mouse model. | Endocrinology 20071001 |
Role of aromatase inhibitor in patients with poor response to clomiphene citrate needs further evaluation. | The journal of obstetrics and gynaecology research 20071001 |
Changes in breast cancer transcriptional profiles after treatment with the aromatase inhibitor, letrozole. | Pharmacogenetics and genomics 20071001 |
Reduced endogenous estrogen delays epididymal development but has no effect on efferent duct morphology in boars. | Reproduction (Cambridge, England) 20071001 |
Aromatase inhibitor and bone. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20071001 |
The early days of letrozole. | Breast cancer research and treatment 20071001 |
The discovery and mechanism of action of letrozole. | Breast cancer research and treatment 20071001 |
Letrozole in the neoadjuvant setting: the P024 trial. | Breast cancer research and treatment 20071001 |
Letrozole in the extended adjuvant setting: MA.17. | Breast cancer research and treatment 20071001 |
Letrozole as upfront endocrine therapy for postmenopausal women with hormone-sensitive breast cancer: BIG 1-98. | Breast cancer research and treatment 20071001 |
A decade of letrozole: FACE. | Breast cancer research and treatment 20071001 |
Safety of aromatase inhibitors in the adjuvant setting. | Breast cancer research and treatment 20071001 |
The patient experience. | Breast cancer research and treatment 20071001 |
Femara and the future: tailoring treatment and combination therapies with Femara. | Breast cancer research and treatment 20071001 |
A comparison of letrozole to gonadotropins for ovulation induction, in subjects who failed to conceive with clomiphene citrate. | Fertility and sterility 20071001 |
Update on the use of letrozole in breast cancer. | Expert opinion on pharmacotherapy 20071001 |
Effects of aromatase inhibitors letrozole and anastrazole on bone metabolism and steroid hormone levels in intact female rats. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20071001 |
Antitumour and biological effects of letrozole and GnRH analogue as primary therapy in premenopausal women with ER and PgR positive locally advanced operable breast cancer. | British journal of cancer 20070911 |
[Antiestrogen treatment in postmenopausal patients with metastatic breast cancer]. | Ugeskrift for laeger 20070910 |
Letrozole and norethisterone acetate in rectovaginal endometriosis. | Fertility and sterility 20070901 |
Letrozole for ovulation induction and fertility preservation by embryo cryopreservation in young women with endometrial carcinoma. | Fertility and sterility 20070901 |
Developmental changes in testicular sensitivity to estrogens throughout fetal and neonatal life. | Toxicological sciences : an official journal of the Society of Toxicology 20070901 |
Estrogen-regulated gene expression predicts response to endocrine therapy in patients with ovarian cancer. | Gynecologic oncology 20070901 |
Prognostic and predictive value of centrally reviewed expression of estrogen and progesterone receptors in a randomized trial comparing letrozole and tamoxifen adjuvant therapy for postmenopausal early breast cancer: BIG 1-98. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070901 |
Oestrogen receptors and linear bone growth. | Acta paediatrica (Oslo, Norway : 1992) 20070901 |
Reducing the risk of late recurrence in hormone-responsive breast cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20070901 |
Reducing the risk of early recurrence in hormone-responsive breast cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20070901 |
Effect of estrogens on skin aging and the potential role of SERMs. | Clinical interventions in aging 20070901 |
Letrozole as adjuvant therapy for postmenopausal women with early breast cancer. | Managed care interface 20070901 |
Clinical activities of the epidermal growth factor receptor family inhibitors in breast cancer. | Biologics : targets & therapy 20070901 |
The molecular genetics of breast cancer and targeted therapy. | Biologics : targets & therapy 20070901 |
Nonsurgical treatment of male infertility: specific and empiric therapy. | Biologics : targets & therapy 20070901 |
Hope for axed cancer-prevention trial. | Nature 20070823 |
Health care costs for the treatment of breast cancer recurrent events: estimates from a UK-based patient-level analysis. | British journal of cancer 20070820 |
Role of gonadotropin-releasing hormone analog in the management of male metastatic breast cancer is uncertain. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070820 |
A new rat model exhibiting both ovarian and metabolic characteristics of polycystic ovary syndrome. | Endocrinology 20070801 |
Histopathology of breast carcinoma following neoadjuvant systemic therapy: a common association between letrozole therapy and central scarring. | Histopathology 20070801 |
Akt-induced endocrine therapy resistance is reversed by inhibition of mTOR signaling. | Annals of oncology : official journal of the European Society for Medical Oncology 20070801 |
Letrozole: present and future role in the treatment of breast cancer. | Expert opinion on pharmacotherapy 20070801 |
Clomiphene citrate: an old favourite lives on. | Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 20070801 |
Fetal safety of letrozole and clomiphene citrate for ovulation induction. | Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 20070801 |
Letrozole effective in ovarian cancer. | The Lancet. Oncology 20070801 |
Development and validation of a spectrophotometric method for estimation of letrozole in bulk and pharmaceutical formulation. | Die Pharmazie 20070801 |
Reducing the risk for breast cancer recurrence after completion of tamoxifen treatment in postmenopausal women. | Clinical therapeutics 20070801 |
Effects of hormonal therapy on cognitive functioning in breast cancer patients: a review of the literature. | Minerva ginecologica 20070801 |
Assisted reproduction and breast cancer. | Minerva ginecologica 20070801 |
A review of lapatinib ditosylate in the treatment of refractory or advanced breast cancer. | Therapeutics and clinical risk management 20070801 |
Dual aromatase-steroid sulfatase inhibitors. | Journal of medicinal chemistry 20070726 |
Debilitating musculoskeletal pain and stiffness with letrozole and exemestane: associated tenosynovial changes on magnetic resonance imaging. | Breast cancer research and treatment 20070701 |
The effects of atamestane and toremifene alone and in combination compared with letrozole on bone, serum lipids and the uterus in an ovariectomized rat model. | Breast cancer research and treatment 20070701 |
Placental expression and molecular characterization of aromatase cytochrome P450 in the spotted hyena (Crocuta crocuta). | Placenta 20070701 |
Continuing with letrozole offers greater benefits. | Journal of cancer research and clinical oncology 20070701 |
Focal adhesion kinase and paxillin: novel regulators of brain sexual differentiation? | Endocrinology 20070701 |
Administration of an inhibitor of estrogen biosynthesis facilitates working memory acquisition in male rats. | Neuroscience research 20070701 |
Superiority of gas chromatography/tandem mass spectrometry assay (GC/MS/MS) for estradiol for monitoring of aromatase inhibitor therapy. | Steroids 20070701 |
Hormonal therapies for early breast cancer: systematic review and economic evaluation. | Health technology assessment (Winchester, England) 20070701 |
Regression of choroidal metastasis from breast carcinoma following Letrozole therapy. | Clinical & experimental ophthalmology 20070701 |
NCI and the STELLAR trial. | Lancet (London, England) 20070630 |
Clinical research. No lifeline for proposed breast cancer prevention trial. | Science (New York, N.Y.) 20070622 |
Adjuvant endocrine therapy for early breast cancer. | Cancer letters 20070618 |
Meta-analysis of clodronate and breast cancer survival. | British journal of cancer 20070618 |
Antiestrogen therapy is active in selected ovarian cancer cases: the use of letrozole in estrogen receptor-positive patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070615 |
Cost-utility of adjuvant hormone therapies with aromatase inhibitors in post-menopausal women with breast cancer: upfront anastrozole, sequential tamoxifen-exemestane and extended tamoxifen-letrozole. | Breast (Edinburgh, Scotland) 20070601 |
Experimental endocrine therapies promote epithelial cytodifferentiation and ciliogenesis in the gerbil female prostate. | Cell and tissue research 20070601 |
Relative potencies of anastrozole and letrozole to suppress estradiol in breast cancer patients undergoing ovarian stimulation before in vitro fertilization. | The Journal of clinical endocrinology and metabolism 20070601 |
Letrozole treatment of precocious puberty in girls with the McCune-Albright syndrome: a pilot study. | The Journal of clinical endocrinology and metabolism 20070601 |
New advances in ovulation induction. | Current opinion in obstetrics & gynecology 20070601 |
Aromatase inhibitors in the treatment of severe endometriosis. | Obstetrics and gynecology 20070601 |
Letrozole and desogestrel-only contraceptive pill for the treatment of stage IV endometriosis. | The Australian & New Zealand journal of obstetrics & gynaecology 20070601 |
Cost-effectiveness of letrozole versus tamoxifen as initial adjuvant therapy in hormone receptor-positive postmenopausal women with early-stage breast cancer. | Clinical breast cancer 20070601 |
The National Cancer Institute of Canada Clinical Trials Group MAP.3 trial: an international breast cancer prevention trial. | Current oncology (Toronto, Ont.) 20070601 |
Aromatase inhibitors and musculoskeletal pain in patients with breast cancer. | Clinical journal of oncology nursing 20070601 |
Pharmacokinetics of letrozole in male and female rats: influence of complexation with hydroxybutenyl-beta cyclodextrin. | The Journal of pharmacy and pharmacology 20070601 |
Placental villous vascular endothelial growth factor expression and vascularization after estrogen suppression during the last two-thirds of baboon pregnancy. | Endocrine 20070601 |
Efficacy of letrozole extended adjuvant therapy according to estrogen receptor and progesterone receptor status of the primary tumor: National Cancer Institute of Canada Clinical Trials Group MA.17. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070520 |
Letrozole compared with tamoxifen as initial adjuvant therapy for breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070520 |
Quantification of carvedilol in human plasma by liquid chromatography using fluorescence detection: application in pharmacokinetic studies. | Journal of pharmaceutical and biomedical analysis 20070509 |
Fas ligand expression in TM4 Sertoli cells is enhanced by estradiol 'in situ' production. | Journal of cellular physiology 20070501 |
Predictors of early relapse in postmenopausal women with hormone receptor-positive breast cancer in the BIG 1-98 trial. | Annals of oncology : official journal of the European Society for Medical Oncology 20070501 |
Toxicity of the aromatase inhibitor letrozole to Japanese medaka (Oryzias latipes) eggs, larvae and breeding adults. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20070501 |
Inhibition of the phosphatidylinositol 3-kinase/Akt pathway improves response of long-term estrogen-deprived breast cancer xenografts to antiestrogens. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070501 |
The Breast International Group 1-98 trial: big results for women with hormone-sensitive early breast cancer. | Expert review of anticancer therapy 20070501 |
Randomized controlled trial of three doses of letrozole for ovulation induction in patients with unexplained infertility. | Reproductive biomedicine online 20070501 |
A novel tocolytic agent: effects of letrozole on gestational length and parturition time. | American journal of perinatology 20070501 |
Novel retinoic acid metabolism blocking agents have potent inhibitory activities on human breast cancer cells and tumour growth. | British journal of cancer 20070423 |
Towards optimal endocrine therapy for hormone-sensitive breast cancer: initial versus sequential adjuvant aromatase inhibition. | Cancer letters 20070418 |
[Clinical study of aromatase inhibitors in advanced breast cancer]. | Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20070418 |
Changes in bone mineral density after adjuvant aromatase inhibitors and fracture risk in breast cancer patients. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070410 |
Pilot study of the impact of letrozole vs. placebo on breast density in women completing 5 years of tamoxifen. | Breast (Edinburgh, Scotland) 20070401 |
Synthesis of DL-standishinal and its related compounds for the studies on structure-activity relationship of inhibitory activity against aromatase. | Bioorganic & medicinal chemistry 20070401 |
[Advancement in endocrine therapy for breast cancer]. | Ai zheng = Aizheng = Chinese journal of cancer 20070401 |
Sex-specific effects of androgen and estrogen on proliferation of the embryonic chicken hypothalamic neurons. | Endocrine 20070401 |
Cost-effectiveness of letrozole, anastrozole and exemestane for early adjuvant breast cancer. | Expert review of pharmacoeconomics & outcomes research 20070401 |
Cancer research. Budget pressure puts high-profile study in doubt. | Science (New York, N.Y.) 20070316 |
The combination of letrozole and trastuzumab as first or second-line biological therapy produces durable responses in a subset of HER2 positive and ER positive advanced breast cancers. | Breast cancer research and treatment 20070301 |
Zoledronic acid inhibits adjuvant letrozole-induced bone loss in postmenopausal women with early breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070301 |
Follicular phase dynamics with combined aromatase inhibitor and follicle stimulating hormone treatment. | The Journal of clinical endocrinology and metabolism 20070301 |
Insulin-like growth factor binding proteins IGFBP3, IGFBP4, and IGFBP5 predict endocrine responsiveness in patients with ovarian cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070301 |
Aromatase inhibitors: a safety comparison. | Expert opinion on drug safety 20070301 |
Letrozole versus testosterone. a single-center pilot study of HIV-infected men who have sex with men on highly active anti-retroviral therapy (HAART) with hypoactive sexual desire disorder and raised estradiol levels. | The journal of sexual medicine 20070301 |
Aromatase inhibitors and male breast cancer. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20070301 |
Clinical evaluation of the use of exemestane as further hormonal therapy after nonsteroidal aromatase inhibitors in postmenopausal metastatic breast cancer patients. | Cancer investigation 20070301 |
First line targeted therapies in breast cancer: focus on bevacizumab. | Biologics : targets & therapy 20070301 |
Biotransformation of letrozole in rat liver microsomes: effects of gender and tamoxifen. | Journal of pharmaceutical and biomedical analysis 20070219 |
Five years of letrozole compared with tamoxifen as initial adjuvant therapy for postmenopausal women with endocrine-responsive early breast cancer: update of study BIG 1-98. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070210 |
Neoadjuvant endocrine therapy in breast cancer. | Cancer treatment reviews 20070201 |
Pharmacogenetics and oncology treatment for breast cancer. | Expert opinion on pharmacotherapy 20070201 |
Optimal treatment strategies in hormone-responsive early breast cancer: the role of aromatase inhibitors. | Onkologie 20070201 |
The prevention and management of distant metastases in women with breast cancer. | Cancer investigation 20070201 |
The FACE trial: letrozole or anastrozole as initial adjuvant therapy? | Cancer investigation 20070201 |
Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women. | The Cochrane database of systematic reviews 20070124 |
Cost-effectiveness of letrozole in the extended adjuvant treatment of women with early breast cancer. | Breast cancer research and treatment 20070101 |
In silico prediction of pregnane X receptor activators by machine learning approaches. | Molecular pharmacology 20070101 |
Neuroprotection by estradiol: a role of aromatase against spine synapse loss after blockade of GABA(A) receptors. | Experimental neurology 20070101 |
Late risk of relapse and mortality among postmenopausal women with estrogen responsive early breast cancer after 5 years of tamoxifen. | Annals of oncology : official journal of the European Society for Medical Oncology 20070101 |
Development and evolution of therapies targeted to the estrogen receptor for the treatment and prevention of breast cancer. | Steroids 20070101 |
Aromatase inhibitors in the adjuvant treatment of postmenopausal women with early breast cancer: Putting safety issues into perspective. | The breast journal 20070101 |
Beta2-agonists and paresthesias in multiple sclerosis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20070101 |
Tamoxifen-associated vasculitis in a breast cancer patient. | World journal of surgical oncology 20070101 |
Economic evaluation of the prevention and treatment of breast cancer--present status and open issues. | Breast cancer (Tokyo, Japan) 20070101 |
Effects of liarozole fumarate (R85246) in combination with tamoxifen on N-methyl-N-nitrosourea (MNU)-induced mammary carcinoma and uterus in the rat model. | BMC cancer 20070101 |
[Pulmonary metastases from endometrial stromal sarcoma may benefit from hormone therapy]. | Revue des maladies respiratoires 20070101 |
Systemic anticancer therapy in gynecological cancer patients with renal dysfunction. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20070101 |
A small animal positron emission tomography study of the effect of chemotherapy and hormonal therapy on the uptake of 2-deoxy-2-[F-18]fluoro-D-glucose in murine models of breast cancer. | Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20070101 |
Neoadjuvant use of endocrine therapy in breast cancer. | The breast journal 20070101 |
[The role of the ovarian steroid aromatase in pathogenesis of reproductive cycles disorders]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20070101 |
Mammographic density does not correlate with Ki-67 expression or cytomorphology in benign breast cells obtained by random periareolar fine needle aspiration from women at high risk for breast cancer. | Breast cancer research : BCR 20070101 |
Bilateral male breast cancer with male potential hypogonadism. | World journal of surgical oncology 20070101 |
Molecular response to aromatase inhibitor treatment in primary breast cancer. | Breast cancer research : BCR 20070101 |
HER-2/neu diagnostics in breast cancer. | Breast cancer research : BCR 20070101 |
Tumour dormancy in breast cancer: an update. | Breast cancer research : BCR 20070101 |
Quality of life issues in relation to the aromatase inhibitor. | The Journal of steroid biochemistry and molecular biology 20070101 |
External influences and priority-setting for anti-cancer agents: a case study of media coverage in adjuvant trastuzumab for breast cancer. | BMC cancer 20070101 |
Aromatase inhibitors in ovarian stimulation. | The Journal of steroid biochemistry and molecular biology 20070101 |
DCIS and aromatase inhibitors. | The Journal of steroid biochemistry and molecular biology 20070101 |
Xenograft models for aromatase inhibitor studies. | The Journal of steroid biochemistry and molecular biology 20070101 |
New experimental models for aromatase inhibitor resistance. | The Journal of steroid biochemistry and molecular biology 20070101 |
Aromatase inhibitors--gene discovery. | The Journal of steroid biochemistry and molecular biology 20070101 |
Breast cancer metastasis to the stomach may mimic primary gastric cancer: report of two cases and review of literature. | World journal of surgical oncology 20070101 |
Effects of steroidal and nonsteroidal aromatase inhibitors on markers of bone turnover in healthy postmenopausal women. | Breast cancer research : BCR 20070101 |
Amping up estrogen receptors in breast cancer. | Breast cancer research : BCR 20070101 |
Pulmonary hypertension caused by metastatic breast cancer and its response to antihormone therapy and chemotherapy. | The breast journal 20070101 |
Bilateral synchronous breast carcinomas followed by a metastasis to the gallbladder: a case report. | World journal of surgical oncology 20070101 |
Management of late recurrence of a low-grade endometrial stromal sarcoma (LGESS): treatment with letrozole. | Anticancer research 20070101 |
Serum epidermal growth factor receptor and HER2 expression in primary and metastatic breast cancer patients. | Breast cancer research : BCR 20070101 |
Clinical trials update: endocrine and biological therapy combinations in the treatment of breast cancer. | Breast cancer research : BCR 20070101 |
Results of letrozole in postmenopausal women after tamoxifen treatment for advanced breast cancer. | Journal of cancer research and therapeutics 20070101 |
[Neoadjuvant endocrine therapy for locally advanced breast cancer]. | La Clinica terapeutica 20070101 |
Trastuzumab : in HER2 and hormone receptor co-positive metastatic breast cancer. | Drugs 20070101 |
Breast tumour angiogenesis. | Breast cancer research : BCR 20070101 |
Arzoxifene: the evidence for its development in the management of breast cancer. | Core evidence 20070101 |
Breast cancer prevention in women with a BRCA1 or BRCA2 mutation. | Open medicine : a peer-reviewed, independent, open-access journal 20070101 |
[Optimal adjuvant hormone therapy in postmenopausal women with hormone-sensitive mammary carcinoma: tamoxifen and the aromatase inhibitors anastrozole, exemestane and letrozole]. | Nederlands tijdschrift voor geneeskunde 20061230 |
What do we know about the mechanisms of aromatase inhibitor resistance? | The Journal of steroid biochemistry and molecular biology 20061201 |
Clinically occult cutaneous metastases. | Journal of the American Academy of Dermatology 20061201 |
Aromatase and breast cancer. | The Journal of steroid biochemistry and molecular biology 20061201 |
Adjuvant therapy with aromatase inhibitors for postmenopausal women with early breast cancer: evidence and ongoing controversy. | Seminars in oncology 20061201 |
Effects of novel retinoic acid metabolism blocking agent (VN/14-1) on letrozole-insensitive breast cancer cells. | Cancer research 20061201 |
Aromatase inhibitors in early breast cancer therapy: a variety of treatment strategies. | Expert opinion on pharmacotherapy 20061201 |
Aromatase inhibitors in ovarian stimulation. | Reproductive biomedicine online 20061201 |
Non-steroidal anti-estrogens in the treatment of breast cancer. | Current opinion in investigational drugs (London, England : 2000) 20061201 |
NSABP B-42: a clinical trial to determine the efficacy of five years of letrozole compared with placebo in patients completing five years of hormonal therapy consisting of an aromatase inhibitor (AI) or tamoxifen followed by an AI in prolonging disease-free survival in postmenopausal women with hormone receptor-positive breast cancer. | Clinical breast cancer 20061201 |
Initial versus sequential adjuvant aromatase inhibitor therapy: a review of the current data. | Current medical research and opinion 20061201 |
Serum epidermal growth factor receptor/HER-2 predicts poor survival in patients with metastatic breast cancer. | Cancer 20061115 |
Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles. | Toxicology 20061110 |
A phase II clinical and pharmacodynamic study of temsirolimus in advanced neuroendocrine carcinomas. | British journal of cancer 20061106 |
Prospective endometrial assessment of breast cancer patients treated with third generation aromatase inhibitors. | Gynecologic oncology 20061101 |
Cost-effectiveness of aromatase inhibitor co-treatment for controlled ovarian stimulation. | Human reproduction (Oxford, England) 20061101 |
Serum insulin-like factor 3 levels during puberty in healthy boys and boys with Klinefelter syndrome. | The Journal of clinical endocrinology and metabolism 20061101 |
Clinical outcomes of ethnic minority women in MA.17: a trial of letrozole after 5 years of tamoxifen in postmenopausal women with early stage breast cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20061101 |
Metastatic breast cancer: an updating. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20061101 |
Comparison of the efficacy of the aromatase inhibitor letrozole and clomiphene citrate as adjuvants to recombinant follicle-stimulating hormone in controlled ovarian hyperstimulation: a prospective, randomized, blinded clinical trial. | Fertility and sterility 20061101 |
Adjuvant trials: Aromatase inhibitors in early breast cancer--are they alike? | Cancer treatment reviews 20061101 |
Optimal sequence of hormonotherapy in advanced breast cancer. | Current opinion in oncology 20061101 |
Safety of adjuvant aromatase inhibitor therapy. | Cancer treatment reviews 20061101 |
Oestrogen synthesis in the hippocampus: role in axon outgrowth. | Journal of neuroendocrinology 20061101 |
Use of an aromatase inhibitor in patients with polycystic ovary syndrome: a prospective randomized trial. | Fertility and sterility 20061101 |
Aromatase destabilizer: novel action of exemestane, a food and drug administration-approved aromatase inhibitor. | Cancer research 20061101 |
Adjuvant endocrine therapy in hormone receptor-positive postmenopausal breast cancer: evolution of NCCN, ASCO, and St Gallen recommendations. | Journal of the National Comprehensive Cancer Network : JNCCN 20061101 |
Effects of adjuvant aromatase inhibitor therapy on lipid profiles. | Expert review of anticancer therapy 20061101 |
Aromatase inhibitors: structural features and biochemical characterization. | Annals of the New York Academy of Sciences 20061101 |
Postmenopausal advanced breast cancer: options for therapy after tamoxifen and aromatase inhibitors. | Breast (Edinburgh, Scotland) 20061001 |
Duration of letrozole treatment and outcomes in the placebo-controlled NCIC CTG MA.17 extended adjuvant therapy trial. | Breast cancer research and treatment 20061001 |
Androgen priming using aromatase inhibitor and hCG during early-follicular-phase GnRH antagonist down-regulation in modified antagonist protocols. | Human reproduction (Oxford, England) 20061001 |
A single intravenous administration of zoledronic acid prevents the bone loss and mechanical compromise induced by aromatase inhibition in rats. | Bone 20061001 |
Letrozole reduces estrogen and gonadotropin exposure in women with breast cancer undergoing ovarian stimulation before chemotherapy. | The Journal of clinical endocrinology and metabolism 20061001 |
The effect of tamoxifen on the pharmacokinetics of letrozole in female rats. | Biopharmaceutics & drug disposition 20061001 |
Preliminary experience with a low-cost stimulation protocol that includes letrozole and human menopausal gonadotropins in normal responders for assisted reproductive technologies. | Fertility and sterility 20061001 |
Microscopic characterization of follicular structures in letrozole-induced polycystic ovarian syndrome in the rat. | Archives of medical research 20061001 |
Role of aromatase inhibitor in ovulation induction in patients with poor response to clomiphene citrate. | The journal of obstetrics and gynaecology research 20061001 |
Update on the use of aromatase inhibitors in breast cancer. | Expert opinion on pharmacotherapy 20061001 |
Aromatase inhibitors and bipolar mood disorder: a case report. | Bipolar disorders 20061001 |
Refining the postmenopausal breast cancer treatment paradigm: the FACE trial. | Expert review of anticancer therapy 20061001 |
Mammalian target of rapamycin inhibitors in combination with letrozole in breast cancer. | Clinical breast cancer 20061001 |
Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis. | Journal of the National Cancer Institute 20060920 |
Combination therapy with aromatase inhibitors: the next era of breast cancer treatment? | British journal of cancer 20060918 |
Preconception and the young cancer survivor. | Maternal and child health journal 20060901 |
In men, peripheral estradiol levels directly reflect the action of estrogens at the hypothalamo-pituitary level to inhibit gonadotropin secretion. | The Journal of clinical endocrinology and metabolism 20060901 |
Suppression of endogenous estrogen during development affects porcine epididymal sperm maturation. | Molecular reproduction and development 20060901 |
Blockade of oestrogen biosynthesis in peripubertal boys: effects on lipid metabolism, insulin sensitivity, and body composition. | European journal of endocrinology 20060901 |
Fertility preservation strategies for breast cancer patients. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060901 |
The emerging role of aromatase inhibitors in the adjuvant management of breast cancer. | Reviews on recent clinical trials 20060901 |
Letrozole: a well-tolerated and effective treatment for breast cancer. | Women's health (London, England) 20060901 |
Quality of life in a randomized control trial? Comments concerning MA 17. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060820 |
Re: Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: updated findings from NCIC CTG MA.17. | Journal of the National Cancer Institute 20060816 |
Effect of letrozole versus placebo on bone mineral density in women with primary breast cancer completing 5 or more years of adjuvant tamoxifen: a companion study to NCIC CTG MA.17. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060801 |
Incidence and management of side effects associated with aromatase inhibitors in the adjuvant treatment of breast cancer in postmenopausal women. | Current medical research and opinion 20060801 |
Randomized phase II trial of letrozole and letrozole plus low-dose metronomic oral cyclophosphamide as primary systemic treatment in elderly breast cancer patients. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060801 |
Role of androgens on MCF-7 breast cancer cell growth and on the inhibitory effect of letrozole. | Cancer research 20060801 |
Aromatase inhibitors in ovarian stimulation for IVF/ICSI: a pilot study. | Reproductive biomedicine online 20060801 |
Letrozole versus human menopausal gonadotrophin in women undergoing intrauterine insemination. | Reproductive biomedicine online 20060801 |
Aromatase inhibitors and bone loss. | Oncology (Williston Park, N.Y.) 20060801 |
Use of aromatase inhibitors to increase final height. | Molecular and cellular endocrinology 20060725 |
Leuprolide acetate plus aromatase inhibition for male breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060720 |
Exemestane after tamoxifen as adjuvant hormonal therapy in postmenopausal women with breast cancer: effects on body composition and lipids. | British journal of cancer 20060717 |
Lack of aromatisation of the 3-keto-4-ene metabolite of tibolone to an estrogenic derivative. | Steroids 20060701 |
Estrogen-independent proliferation is present in estrogen-receptor HER2-positive primary breast cancer after neoadjuvant letrozole. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060701 |
Does adjuvant therapy with letrozole improve survival in postmenopausal women with early-stage breast cancer? | Nature clinical practice. Oncology 20060701 |
Cost-effectiveness of extended adjuvant letrozole therapy after 5 years of adjuvant tamoxifen therapy in postmenopausal women with early-stage breast cancer. | The American journal of managed care 20060701 |
Second- and third-generation aromatase inhibitors as first-line endocrine therapy in postmenopausal metastatic breast cancer patients: a pooled analysis of the randomised trials. | British journal of cancer 20060619 |
Letrozole for brain and scalp metastases from breast cancer--a case report. | Breast (Edinburgh, Scotland) 20060601 |
Harm or benefit of hormonal treatment in metastatic low-grade endometrial stromal sarcoma: single center experience with 10 cases and review of the literature. | Gynecologic oncology 20060601 |
Optimizing the use of aromatase inhibitors in adjuvant therapy for postmenopausal patients with hormone-responsive early breast cancer: current and future prospects. | Journal of cancer research and clinical oncology 20060601 |
Efficacy of combined metformin-letrozole in comparison with metformin-clomiphene citrate in clomiphene-resistant infertile women with polycystic ovarian disease. | Human reproduction (Oxford, England) 20060601 |
Extended breast cancer treatment with an aromatase inhibitor (Letrozole) after tamoxifen: why, who and how long? | European journal of obstetrics, gynecology, and reproductive biology 20060601 |
Congenital malformations among 911 newborns conceived after infertility treatment with letrozole or clomiphene citrate. | Fertility and sterility 20060601 |
Use of letrozole versus clomiphene citrate combined with gonadotropins in intrauterine insemination cycles: a pilot study. | Fertility and sterility 20060601 |
Adjuvant aromatase inhibitor therapy for early breast cancer: A review of the most recent data. | Journal of surgical oncology 20060601 |
Adjuvant aromatase inhibitors for early breast cancer after chemotherapy-induced amenorrhoea: caution and suggested guidelines. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060601 |
Extended adjuvant therapy with letrozole: reducing the risk of recurrence. | Expert review of anticancer therapy 20060601 |
[Introduction of new drug: letrozole, a new non-steroidal aromatase inhibitor for the treatment of postmenopausal women with breast cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060601 |
Management of choroidal metastases from breast carcinomas using aromatase inhibitors. | Current opinion in ophthalmology 20060601 |
Risk of cancer treatment-associated bone loss and fractures among women with breast cancer receiving aromatase inhibitors. | Clinical breast cancer 20060601 |
Optimising adjuvant endocrine treatment of breast cancer with aromatase inhibitors. | International journal of clinical practice 20060601 |
Breast cancer (metastatic). | Clinical evidence 20060601 |
Effects of third-generation aromatase inhibitors on bone. | European journal of cancer (Oxford, England : 1990) 20060501 |
Proliferation and apoptosis of hippocampal granule cells require local oestrogen synthesis. | Journal of neurochemistry 20060501 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Treatment with the aromatase inhibitor letrozole during adolescence increases near-final height in boys with constitutional delay of puberty. | Clinical endocrinology 20060501 |
Fertility preservation in young women undergoing breast cancer therapy. | The oncologist 20060501 |
Pharmacoeconomic analysis of adjuvant therapy with exemestane, anastrozole, letrozole or tamoxifen in postmenopausal women with operable and estrogen receptor-positive breast cancer. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20060501 |
Primary hormone treatment in postmenopausal women with breast cancer. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20060501 |
Proliferation, steroid receptors and clinical/pathological response in breast cancer treated with letrozole. | British journal of cancer 20060410 |
Letrozole or tamoxifen in early breast cancer. | The New England journal of medicine 20060406 |
Letrozole or tamoxifen in early breast cancer. | The New England journal of medicine 20060406 |
Letrozole or tamoxifen in early breast cancer. | The New England journal of medicine 20060406 |
Paternal responsiveness in biparental dwarf hamsters (Phodopus campbelli) does not require estradiol. | Hormones and behavior 20060401 |
Pregnancy outcome in infertile patients with polycystic ovary syndrome who were treated with metformin. | Fertility and sterility 20060401 |
Letrozole vs. clomiphene citrate in patients with ovulatory infertility. | Fertility and sterility 20060401 |
The use of early adjuvant aromatase inhibitor therapy: contributions from the BIG 1-98 letrozole trial. | Seminars in oncology 20060401 |
Preventing relapse beyond 5 years: the MA.17 extended adjuvant trial. | Seminars in oncology 20060401 |
Management of cancer-treatment-induced bone loss in postmenopausal women undergoing adjuvant breast cancer therapy: a Z-FAST update. | Seminars in oncology 20060401 |
Future directions in the treatment of hormone-sensitive advanced breast cancer: the RAD001 (Everolimus)-letrozole clinical program. | Seminars in oncology 20060401 |
COMPRENDO: Focus and approach. | Environmental health perspectives 20060401 |
Bisphenol A induces superfeminization in the ramshorn snail Marisa cornuarietis(Gastropoda: Prosobranchia) at environmentally relevant concentrations. | Environmental health perspectives 20060401 |
A 3-year prospective study of the effects of adjuvant treatments on cognition in women with early stage breast cancer. | British journal of cancer 20060327 |
Aromatase inhibitors and breast cancer. | Minerva endocrinologica 20060301 |
The effects of testosterone and oestrogen on gonadectomised and intact male rat anterior pituitary mitotic and apoptotic activity. | The Journal of endocrinology 20060301 |
[The evolving role of endocrine therapy for breast cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20060301 |
Resumption of menses with initiation of letrozole after five years of amenorrhea on tamoxifen: caution needed when using tamoxifen followed by aromatase inhibitors. | Cancer investigation 20060301 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20060301 |
Serum endostatin and bFGF as predictive factors in advanced breast cancer patients treated with letrozole. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20060301 |
Should aromatase inhibitors be used as initial adjuvant treatment or sequenced after tamoxifen? | British journal of cancer 20060227 |
Novel sulfonanilide analogues suppress aromatase expression and activity in breast cancer cells independent of COX-2 inhibition. | Journal of medicinal chemistry 20060223 |
Inhibition of human CYP19 by azoles used as antifungal agents and aromatase inhibitors, using a new LC-MS/MS method for the analysis of estradiol product formation. | Toxicology 20060215 |
Neoadjuvant endocrine therapy in breast cancer. | Breast (Edinburgh, Scotland) 20060201 |
Fulvestrant, a new treatment option for advanced breast cancer: tolerability versus existing agents. | Annals of oncology : official journal of the European Society for Medical Oncology 20060201 |
Dehydroepiandrosterone sulfate is neuroprotective when administered either before or after injury in a focal cortical cold lesion model. | Endocrinology 20060201 |
Toxic epidermal necrolysis in patient with breast cancer receiving letrozole. | The Lancet. Oncology 20060201 |
Locally produced estrogen promotes fetal rat metatarsal bone growth; an effect mediated through increased chondrocyte proliferation and decreased apoptosis. | The Journal of endocrinology 20060201 |
ErbB receptor signaling and therapeutic resistance to aromatase inhibitors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060201 |
Adjuvant endocrine therapy for postmenopausal women with early breast cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060201 |
Anastrozole as an adjuvant endocrine treatment for postmenopausal patients with breast cancer: emerging data. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060201 |
Effectiveness of letrozole in the breast cancer treatment continuum. | Breast (Edinburgh, Scotland) 20060201 |
Review of the development of letrozole and its use in advanced breast cancer and in the neoadjuvant setting. | Breast (Edinburgh, Scotland) 20060201 |
The extended adjuvant NCIC CTG MA.17 trials: initial and rerandomization studies. | Breast (Edinburgh, Scotland) 20060201 |
The evolving role of letrozole in the adjuvant setting: first results from the large, phase III, randomized trial BIG 1-98. | Breast (Edinburgh, Scotland) 20060201 |
Improving bone health in patients with early breast cancer by adding bisphosphonates to letrozole: the Z-ZO-E-ZO-FAST program. | Breast (Edinburgh, Scotland) 20060201 |
Emerging data on optimal adjuvant endocrine therapy: Breast International Group trial 1-98/MA.17. | Clinical breast cancer 20060201 |
A new era in ovulation induction. | Fertility and sterility 20060201 |
Letrozole induction of ovulation in women with clomiphene citrate-resistant polycystic ovary syndrome may not depend on the period of infertility, the body mass index, or the luteinizing hormone/follicle-stimulating hormone ratio. | Fertility and sterility 20060201 |
Synaptic plasticity in the hippocampus: effects of estrogen from the gonads or hippocampus? | Neurochemical research 20060201 |
Does HER2/neu overexpression in breast cancer influence adjuvant chemotherapy and hormonal therapy choices by Ontario physicians? A physician survey. | Current oncology (Toronto, Ont.) 20060201 |
[Interactions between radiation and hormonal therapy in breast cancer: simultaneous or sequential treatment]. | Orvosi hetilap 20060122 |
Latest studies hint at survival advantage with aromatase inhibitors in early breast cancer. | Journal of the National Cancer Institute 20060118 |
Current management of treatment-induced bone loss in women with breast cancer treated in the United Kingdom. | British journal of cancer 20060116 |
Reducing estrogen synthesis does not affect gonadotropin secretion in the developing boar. | Biology of reproduction 20060101 |
Direct and indirect effects of estrogen on rat hippocampus. | Neuroscience 20060101 |
Letrozole as adjuvant endocrine therapy in postmenopausal women with breast cancer. | Expert review of anticancer therapy 20060101 |
Hormonal therapy in epithelial ovarian cancer. | Expert review of anticancer therapy 20060101 |
A randomized trial of superovulation with two different doses of letrozole. | Fertility and sterility 20060101 |
Reverting estrogen-receptor-negative phenotype in HER-2-overexpressing advanced breast cancer patients exposed to trastuzumab plus chemotherapy. | Breast cancer research : BCR 20060101 |
Inhibition of hippocampal estrogen synthesis causes region-specific downregulation of synaptic protein expression in hippocampal neurons. | Hippocampus 20060101 |
Estrogen receptors as therapeutic targets in breast cancer. | Current topics in medicinal chemistry 20060101 |
Aromatase inhibitors in breast cancer: a review of cost considerations and cost effectiveness. | PharmacoEconomics 20060101 |
Cost effectiveness of extended adjuvant letrozole in postmenopausal women after adjuvant tamoxifen therapy: the UK perspective. | PharmacoEconomics 20060101 |
Letrozole : in postmenopausal hormone-responsive early-stage breast cancer. | Drugs 20060101 |
Letrozole in postmenopausal hormone-responsive early-stage breast cancer : a viewpoint by Laura B. Michaud. | Drugs 20060101 |
Letrozole in postmenopausal hormone-responsive early-stage breast cancer: a viewpoint by Gerald M. Higa. | Drugs 20060101 |
Phase II study of gemcitabine, doxorubicin and paclitaxel (GAT) as first-line chemotherapy for metastatic breast cancer: a translational research experience. | BMC cancer 20060101 |
Does survival increase in metastatic breast cancer with recently available anticancer drugs? | Oncology research 20060101 |
Reducing estrogen synthesis in developing boars increases testis size and total sperm production. | Journal of andrology 20060101 |
Comparison of letrozole and clomiphene citrate in women with polycystic ovaries undergoing ovarian stimulation. | The Journal of international medical research 20060101 |
Is testosterone or estradiol the hormone of desire? A novel study of the effects of testosterone treatment and aromatase inhibition in postmenopausal women. | Menopause (New York, N.Y.) 20060101 |
Effects of aromatase inhibition on sexual function and well-being in postmenopausal women treated with testosterone: a randomized, placebo-controlled trial. | Menopause (New York, N.Y.) 20060101 |
Third-line hormonal treatment with exemestane in postmenopausal patients with advanced breast cancer progressing on letrozole or anastrozole. A phase II trial conducted by the Hellenic Group of Oncology (HELGO). | Tumori 20060101 |
Letrozole: a pharmacoeconomic review of its use in postmenopausal women with breast cancer. | PharmacoEconomics 20060101 |
Estrogen receptors: role in breast cancer. | Critical reviews in clinical laboratory sciences 20060101 |
Disease-free survival was greater with letrozole than tamoxifen in postmenopausal women with early breast cancer. | ACP journal club 20060101 |
Efficacy and tolerability of high dose 'ethinylestradiol' in post-menopausal advanced breast cancer patients heavily pre-treated with endocrine agents. | World journal of surgical oncology 20060101 |
Testosterone aromatization and cognition in women: a randomized, placebo-controlled trial. | Menopause (New York, N.Y.) 20060101 |
Mammary Paget's disease occurring after mastectomy. | World journal of surgical oncology 20060101 |
Cardiovascular safety profiles of aromatase inhibitors : a comparative review. | Drug safety 20060101 |
Adjuvant endocrine therapy for postmenopausal breast cancer in the era of aromatase inhibitors: an update. | International seminars in surgical oncology : ISSO 20060101 |
Endometrial safety of third generation aromatase inhibitors versus tamoxifen in breast cancer patients. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101 |
Bone safety of aromatase inhibitors versus tamoxifen. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101 |
Presence of apoptotic and nonapoptotic disseminated tumor cells reflects the response to neoadjuvant systemic therapy in breast cancer. | Breast cancer research : BCR 20060101 |
A fast liquid chromatographic/mass spectrometric screening method for the simultaneous detection of synthetic glucocorticoids, some stimulants, anti-oestrogen drugs and synthetic anabolic steroids. | Rapid communications in mass spectrometry : RCM 20060101 |
Appraising adjuvant aromatase inhibitor therapy. | The oncologist 20060101 |
Neoadjuvant use of hormonal therapy in elderly patients with early or locally advanced hormone receptor-positive breast cancer. | The oncologist 20060101 |
[Correlation of hormone-metabolic status in breast cancer and effectiveness of adjuvant hormone therapy]. | Voprosy onkologii 20060101 |
[Current status of breast cancer chemoprevention]. | Revista da Associacao Medica Brasileira (1992) 20060101 |
A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer. | The New England journal of medicine 20051229 |
Aromatase inhibitors--a triumph of translational oncology. | The New England journal of medicine 20051229 |
Effect of exemestane on tamoxifen pharmacokinetics in postmenopausal women treated for breast cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20051215 |
Inhibition of estrogen biosynthesis with a potent aromatase inhibitor increases predicted adult height in boys with idiopathic short stature: a randomized controlled trial. | The Journal of clinical endocrinology and metabolism 20051201 |
Growth inhibition of estrogen receptor-positive and aromatase-positive human breast cancer cells in monolayer and spheroid cultures by letrozole, anastrozole, and tamoxifen. | The Journal of steroid biochemistry and molecular biology 20051201 |
Human aromatase: gene resequencing and functional genomics. | Cancer research 20051201 |
Future perspectives in the medical treatment of endometriosis. | Obstetrical & gynecological survey 20051201 |
Extended adjuvant endocrine therapy of early breast cancer. | Current medical research and opinion 20051201 |
Oral ovulation induction agents combined with low-dose gonadotropin injections and intrauterine insemination: cost- and clinical effectiveness. | The Journal of reproductive medicine 20051201 |
Over expression of aromatase protein is highly related to MMPs levels in human breast carcinomas. | Journal of experimental & clinical cancer research : CR 20051201 |
Metastatic mucinous carcinoma of the eyelid. | The Malaysian journal of pathology 20051201 |
New developments in the treatment of postmenopausal breast cancer. | Trends in endocrinology and metabolism: TEM 20051101 |
When clinical trials are compromised: a perspective from a patient advocate. | PLoS medicine 20051101 |
The use of aromatase inhibitors in adjuvant therapy for early breast cancer. | Cancer chemotherapy and pharmacology 20051101 |
Are all aromatase inhibitors the same? A review of controlled clinical trials in breast cancer. | Clinical therapeutics 20051101 |
Comparative assessment in young and elderly men of the gonadotropin response to aromatase inhibition. | The Journal of clinical endocrinology and metabolism 20051001 |
New aromatase inhibitors as second-line endocrine therapy in postmenopausal patients with metastatic breast carcinoma: a pooled analysis of the randomized trials. | Cancer 20051001 |
Assessment of quality of life in MA.17: a randomized, placebo-controlled trial of letrozole after 5 years of tamoxifen in postmenopausal women. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051001 |
Antiestrogens upregulate estrogen receptor beta expression and inhibit adrenocortical H295R cell proliferation. | Journal of molecular endocrinology 20051001 |
Successful treatment of an aggressive recurrent post-menopausal endometriosis with an aromatase inhibitor. | Reproductive biomedicine online 20051001 |
Defining the roles of aromatase inhibitors in the adjuvant treatment of early-stage breast cancer. | Clinical breast cancer 20051001 |
Serum lipid profiles in patients receiving endocrine treatment for breast cancer--the results from the Celecoxib Anti-Aromatase Neoadjuvant (CAAN) Trial. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20051001 |
Changing the gold standard in adjuvant therapy for breast cancer:from tamoxifen to aromatase inhibition. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20051001 |
Options for preservation of fertility in women. | The New England journal of medicine 20050929 |
Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: updated findings from NCIC CTG MA.17. | Journal of the National Cancer Institute 20050907 |
Comparison of HER-2 overexpression in primary breast cancer and metastatic sites and its effect on biological targeting therapy of metastatic disease. | British journal of cancer 20050905 |
Quality-adjusted survival in a crossover trial of letrozole versus tamoxifen in postmenopausal women with advanced breast cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20050901 |
Circulating antiandrogenic activity in children with congenital adrenal hyperplasia during peroral flutamide treatment. | The Journal of clinical endocrinology and metabolism 20050901 |
Recent advances in the use of aromatase inhibitors for women with postmenopausal breast cancer. | The journal of the British Menopause Society 20050901 |
[Aromatase inhibitor letrozole induces sex inversion in the protogynous red spotted grouper (Epinephelus akaara).]. | Sheng li xue bao : [Acta physiologica Sinica] 20050825 |
Letrozole in the extended adjuvant treatment of postmenopausal women with history of early-stage breast cancer who have completed 5 years of adjuvant tamoxifen. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050815 |
Oxytocin mediates the estrogen-dependent contractile activity of endothelin-1 in human and rabbit epididymis. | Endocrinology 20050801 |
Long-term risk of breast cancer recurrence: the need for extended adjuvant therapy. | Journal of cancer research and clinical oncology 20050801 |
Selective oestrogen receptor modulators, aromatase inhibitors and the female breast. | Current opinion in obstetrics & gynecology 20050801 |
New approaches to reverse resistance to hormonal therapy in human breast cancer. | Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20050801 |
Effects of aromatase inhibitors on proliferation and apoptosis in eutopic endometrial cell cultures from patients with endometriosis. | Fertility and sterility 20050801 |
The role of aromatase inhibitors as adjuvant therapy for early breast cancer in postmenopausal women. | European journal of cancer (Oxford, England : 1990) 20050801 |
Role of aromatase inhibitors in breast cancer. | British journal of cancer 20050801 |
Potential use of COX-2-aromatase inhibitor combinations in breast cancer. | British journal of cancer 20050801 |
Bone loss and the aromatase inhibitors. | British journal of cancer 20050801 |
The effects of aromatase inhibitors on lipids and thrombosis. | British journal of cancer 20050801 |
Sequencing of aromatase inhibitors. | British journal of cancer 20050801 |
The evolving role of aromatase inhibitors in adjuvant breast cancer therapy. | Clinical breast cancer 20050801 |
[Aromatase inhibitors in the treatment of breast cancer: current status and some problems]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20050801 |
Serum HER-2/neu conversion to positive at the time of disease progression in patients with breast carcinoma on hormone therapy. | Cancer 20050715 |
Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050715 |
The aromatase inhibitors in early breast cancer: who, when, and why? | The Medical journal of Australia 20050704 |
Fertility preservation in breast cancer patients: a prospective controlled comparison of ovarian stimulation with tamoxifen and letrozole for embryo cryopreservation. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050701 |
Hormonal treatment with aromatase inhibitors for patients with endometrial stromal sarcoma. | Gynecologic oncology 20050701 |
The aromatase inhibitor letrozole increases the concentration of intraovarian androgens and improves in vitro fertilization outcome in low responder patients: a pilot study. | Fertility and sterility 20050701 |
Letrozole in the treatment of breast cancer. | Expert opinion on pharmacotherapy 20050701 |
Growth factor signalling in clinical breast cancer and its impact on response to conventional therapies: the Edinburgh experience. | Endocrine-related cancer 20050701 |
Activation of mitogen-activated protein kinase in xenografts and cells during prolonged treatment with aromatase inhibitor letrozole. | Cancer research 20050615 |
Additive antitumor effect of aromatase inhibitor letrozole and antiestrogen fulvestrant in a postmenopausal breast cancer model. | Cancer research 20050615 |
A comparison of fulvestrant and the third-generation aromatase inhibitors in the second-line treatment of postmenopausal women with advanced breast cancer. | Cancer treatment reviews 20050601 |
Further evidence on the safety and success of ovarian stimulation with letrozole and tamoxifen in breast cancer patients undergoing in vitro fertilization to cryopreserve their embryos for fertility preservation. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050601 |
Beta-interferon and interleukin-2 prolong more than three times the survival of 26 consecutive endocrine dependent breast cancer patients with distant metastases: an exploratory trial. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20050601 |
Prediction of genotoxicity of chemical compounds by statistical learning methods. | Chemical research in toxicology 20050601 |
Adjuvant hormone therapy for breast cancer: alternatives to tamoxifen. | Prescrire international 20050601 |
[Consensus Meeting of the 9th International Conference on Primary Therapy of Early Breast Cancer (St. Gall, January 26-29, 2005)]. | Gynakologisch-geburtshilfliche Rundschau 20050601 |
Adjuvant therapy for breast cancer. | Minerva ginecologica 20050601 |
Skeletal health in postmenopausal survivors of early breast cancer. | International journal of cancer 20050510 |
Phase II study of sequential hormonal therapy with anastrozole/exemestane in advanced and metastatic breast cancer. | British journal of cancer 20050509 |
Letrozole normalizes serum testosterone in severely obese men with hypogonadotropic hypogonadism. | Diabetes, obesity & metabolism 20050501 |
Aromatase inhibitors in the treatment of breast cancer. | Endocrine reviews 20050501 |
The influence of letrozole on serum lipid concentrations in postmenopausal women with primary breast cancer who have completed 5 years of adjuvant tamoxifen (NCIC CTG MA.17L). | Annals of oncology : official journal of the European Society for Medical Oncology 20050501 |
Stimulating effects of androgen on proliferation of cultured ovarian germ cells through androgenic and estrogenic actions in embryonic chickens. | Domestic animal endocrinology 20050501 |
The role of growth factor receptor pathways in human breast cancer cells adapted to long-term estrogen deprivation. | Cancer research 20050501 |
Diabetes insipidus caused by isolated intracranial metatstases in patient with breast cancer. | Journal of neuro-oncology 20050501 |
Aromatase inhibitors for therapy of advanced breast cancer. | The Journal of steroid biochemistry and molecular biology 20050501 |
Aromatase and comparative response to its inhibitors in two types of endometrial cancer. | The Journal of steroid biochemistry and molecular biology 20050501 |
Model systems: mechanisms involved in the loss of sensitivity to letrozole. | The Journal of steroid biochemistry and molecular biology 20050501 |
Clinical and biomarker endpoint analysis in neoadjuvant endocrine therapy trials. | The Journal of steroid biochemistry and molecular biology 20050501 |
Aromatase inhibitors: cellular and molecular effects. | The Journal of steroid biochemistry and molecular biology 20050501 |
Surgical issues surrounding use of aromatase inhibitors. | The Journal of steroid biochemistry and molecular biology 20050501 |
Serum soluble epidermal growth factor receptor concentrations decrease in postmenopausal metastatic breast cancer patients treated with letrozole. | Cancer research 20050415 |
Aromatase inhibition: translation into a successful therapeutic approach. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050415 |
Estrogen elicits cortical zone-specific effects on development of the primate fetal adrenal gland. | Endocrinology 20050401 |
Successful use of letrozole in male breast cancer: a case report and review of hormonal therapy for male breast cancer. | Journal of surgical oncology 20050401 |
[San Antonio Breast Cancer Symposium -- highlights 2004]. | Zentralblatt fur Gynakologie 20050401 |
Letrozole-, anastrozole-, and tamoxifen-responsive genes in MCF-7aro cells: a microarray approach. | Molecular cancer research : MCR 20050401 |
Efficacy of letrozole for advanced breast cancer in postmenopausal patients. | Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20050401 |
Role of fulvestrant in sequential hormonal therapy for advanced, hormone receptor-positive breast cancer in postmenopausal women. | Clinical breast cancer 20050401 |
Anastrozole. | Drugs of today (Barcelona, Spain : 1998) 20050401 |
Phase II study of weekly vinorelbine and 24-h infusion of high-dose 5-fluorouracil plus leucovorin as first-line treatment of advanced breast cancer. | British journal of cancer 20050328 |
Aromatase inhibitors in advanced breast cancer: there are efficacy differences. | British journal of cancer 20050328 |
Innovations in antineoplastic therapy. | The Nursing clinics of North America 20050301 |
Letrozole better than tamoxifen in postmenopausal women. | The Lancet. Oncology 20050301 |
Cost-effectiveness of letrozole versus tamoxifen as first-line hormonal therapy in treating postmenopausal women with advanced breast cancer in Japan. | Gan to kagaku ryoho. Cancer & chemotherapy 20050301 |
The effect of letrozole on bone age progression, predicted adult height, and adrenal gland function. | Journal of pediatric endocrinology & metabolism : JPEM 20050301 |
Letrozole improves disease-free survival vs tamoxifen in adjuvant treatment of early breast cancer. | Oncology (Williston Park, N.Y.) 20050301 |
17beta-Hydroxysteroid dehydrogenases involved in local oestrogen synthesis have prognostic significance in breast cancer. | British journal of cancer 20050214 |
Letrozole significantly improves growth potential in a pubertal boy with growth hormone deficiency. | Pediatrics 20050201 |
Pubertal upregulation of erythropoiesis in boys is determined primarily by androgen. | The Journal of pediatrics 20050201 |
Endocrine treatment options for advanced breast cancer--the role of fulvestrant. | European journal of cancer (Oxford, England : 1990) 20050201 |
The choice of systemic adjuvant therapy in receptor-positive early breast cancer. | European journal of cancer (Oxford, England : 1990) 20050201 |
Pregnancy outcome after the use of an aromatase inhibitor for ovarian stimulation. | American journal of obstetrics and gynecology 20050201 |
Using aromatase inhibitors in the neoadjuvant setting: evolution or revolution? | Cancer treatment reviews 20050201 |
Adjuvant use of aromatase inhibitors in postmenopausal women with breast cancer. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050201 |
Are aromatase inhibitors superior to antiestrogens? | The Journal of steroid biochemistry and molecular biology 20050201 |
A letrozole-based dual aromatase-sulphatase inhibitor with in vivo activity. | The Journal of steroid biochemistry and molecular biology 20050201 |
Oral anti-oestrogens and medical adjuncts for subfertility associated with anovulation. | The Cochrane database of systematic reviews 20050125 |
Therapeutic observations in MCF-7 aromatase xenografts. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050115 |
Endocrine therapy trials of aromatase inhibitors for breast cancer in the adjuvant and prevention settings. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050115 |
Prevention of hormone-related cancers: breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050110 |
Aromatase 2004, Edinburgh, UK, 6-8 September 2004. | Breast cancer research : BCR 20050101 |
Letrozole sensitizes breast cancer cells to ionizing radiation. | Breast cancer research : BCR 20050101 |
Deficits in plasma oestradiol measurement in studies and management of breast cancer. | Breast cancer research : BCR 20050101 |
Hormonal profile and endometrial morphology in letrozole-controlled ovarian hyperstimulation in ovulatory infertile patients. | Fertility and sterility 20050101 |
Interactions between antiretrovirals and antineoplastic drug therapy. | Clinical pharmacokinetics 20050101 |
Clinical trial update: National Cancer Institute of Canada. | Breast cancer research : BCR 20050101 |
Aromatase expression in ovarian epithelial cancers. | The Journal of steroid biochemistry and molecular biology 20050101 |
Endogenous aromatization of testosterone results in growth stimulation of the human MCF-7 breast cancer cell line. | The Journal of steroid biochemistry and molecular biology 20050101 |
Optimizing the treatment of metastatic breast cancer. | Breast cancer research and treatment 20050101 |
Aromatase inhibitors in the treatment of early and advanced breast cancer. | Acta oncologica (Stockholm, Sweden) 20050101 |
Aromatase inhibitors as add-on treatment for men with epilepsy. | Expert review of neurotherapeutics 20050101 |
Aromatase inhibitors as adjuvant therapy for postmenopausal patients with early stage breast cancer. | CA: a cancer journal for clinicians 20050101 |
[Comparison of letrozole and exemestane used in non-adjuvant therapy of endometrial carcinoma]. | Voprosy onkologii 20050101 |
Endocrinology and hormone therapy in breast cancer: selective oestrogen receptor modulators and downregulators for breast cancer - have they lost their way? | Breast cancer research : BCR 20050101 |
Clinical utility of serum HER2/neu in monitoring and prediction of progression-free survival in metastatic breast cancer patients treated with trastuzumab-based therapies. | Breast cancer research : BCR 20050101 |
Maintenance hormone therapy with letrozole after first-line chemotherapy for advanced breast cancer. | Oncology 20050101 |
The effects of progesterone, medroxyprogesterone acetate, and norethisterone on growth factor- and estradiol-treated human cancerous and noncancerous breast cells. | Menopause (New York, N.Y.) 20050101 |
Safety considerations of adjuvant therapy in early breast cancer in postmenopausal women. | Oncology 20050101 |
Predictors of primary breast cancers responsiveness to preoperative epirubicin/cyclophosphamide-based chemotherapy: translation of microarray data into clinically useful predictive signatures. | Journal of translational medicine 20050101 |
Guidelines, guidelines and more guidelines: and we still do not know how to follow-up patients with breast cancer. | World journal of surgical oncology 20050101 |
Estrogen synthesis in the central nucleus of the amygdala following middle cerebral artery occlusion: role in modulating neurotransmission. | Neuroscience 20050101 |
Early stopping of clinical trials. | Breast cancer research : BCR 20050101 |
The role of aromatase inhibitors in ameliorating deleterious effects of ovarian stimulation on outcome of infertility treatment. | Reproductive biology and endocrinology : RB&E 20050101 |
Comparative bioavailability study of two preparations of letrozole in healthy subjects. | Arzneimittel-Forschung 20050101 |
Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts. | Breast cancer research : BCR 20050101 |
Identification of the aromatase inhibitor letrozole in urine by gas chromatography/mass spectrometry. | Rapid communications in mass spectrometry : RCM 20050101 |
Unilateral anterior uveitis complicating zoledronic acid therapy in breast cancer. | BMC cancer 20050101 |
Response of recurrent uterine high-grade malignant mixed müllerian tumor to letrozole. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20050101 |
Neurosteroid synthesis in the hippocampus: role in synaptic plasticity. | Neuroscience 20050101 |
Benefit with aromatase inhibitors in the adjuvant setting for postmenopausal women with breast cancer. | MedGenMed : Medscape general medicine 20050101 |
Sequential treatment with exemestane and non-steroidal aromatase inhibitors in advanced breast cancer. | Oncology 20050101 |
Aromatase inhibitors as adjuvant therapy for postmenopausal women: a therapeutic advance but many unresolved questions. | Breast cancer research : BCR 20050101 |
Single colon metastasis from breast cancer: a clinical case report. | Tumori 20050101 |
Aromatase inhibitors: changing the face of endocrine therapy for breast cancer. | Breast disease 20050101 |
Primarily tamoxifen-unresponsive, steroid receptor-positive breast cancer may respond to an aromatase inhibition: a pilot study. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20050101 |
Lapatinib: the evidence for its therapeutic value in metastatic breast cancer. | Core evidence 20050101 |
Synthesis and biological evaluation of 4-imidazolylflavans as nonsteroidal aromatase inhibitors. | Bioorganic chemistry 20041201 |
Recent advances in endocrine therapy for postmenopausal women with early breast cancer: implications for treatment and prevention. | Annals of oncology : official journal of the European Society for Medical Oncology 20041201 |
Management of neuroendocrine differentiated breast carcinoma. | Breast (Edinburgh, Scotland) 20041201 |
The responsiveness of a tumour to any kind of therapy is reflected by the objective response rate. | European journal of cancer (Oxford, England : 1990) 20041201 |
Low-grade endometrial stromal sarcoma treated with the aromatase inhibitor letrozole. | Gynecologic oncology 20041201 |
Neoadjuvant endocrine therapy in primary breast cancer. | Clinical breast cancer 20041201 |
Are all aromatase inhibitors the same? A review of the current evidence. | Breast (Edinburgh, Scotland) 20041201 |
Long-term implications of bone loss in breast cancer. | Breast (Edinburgh, Scotland) 20041201 |
A randomized trial of letrozole versus clomiphene citrate in women undergoing superovulation. | Fertility and sterility 20041201 |
[Tamoxifen and aromatase inhibitors in the treatment of breast cancer in menopausal women: pharmacological and clinical aspects]. | Bulletin du cancer 20041201 |
Advances in endocrine therapy for breast cancer: considering efficacy, safety, and quality of life. | Clinical journal of oncology nursing 20041201 |
Aromatase inhibitors and breast cancer: time for a change? | International journal of clinical practice 20041201 |
Aromatase inhibitors in advanced breast cancer. | Seminars in oncology 20041201 |
Aromatase inhibitors in early breast cancer therapy. | Seminars in oncology 20041201 |
Changing clinical practice: extending the benefits of adjuvant endocrine therapy in breast cancer. | Seminars in oncology 20041201 |
Optimizing bisphosphonate therapy in patients with breast cancer on endocrine therapy. | Seminars in oncology 20041201 |
Aromatase inhibitors in the management of early breast cancer: optimizing the clinical benefit. | Seminars in oncology 20041201 |
[Aromatase inhibitors in adjuvant setting in breast cancer]. | Bulletin du cancer 20041201 |
Biochemical and biological characterization of a novel anti-aromatase coumarin derivative. | The Journal of biological chemistry 20041112 |
Endocrine approaches for the treatment of early and advanced breast cancer in postmenopausal women. | The international journal of biochemistry & cell biology 20041101 |
Cellular mechanisms of sex determination in the red-eared slider turtle, Trachemys scripta. | Mechanisms of development 20041101 |
Steroid-free medium discloses oestrogenic effects of the bisphosphonate clodronate on breast cancer cells. | British journal of cancer 20041101 |
Evidence for concurrent effects of exposure to environmental cadmium and lead on hepatic CYP2A6 phenotype and renal function biomarkers in nonsmokers. | Environmental health perspectives 20041101 |
Regulation of placental vascular endothelial growth/permeability factor expression and angiogenesis by estrogen during early baboon pregnancy. | The Journal of clinical endocrinology and metabolism 20041101 |
Effects of exemestane and tamoxifen in a postmenopausal breast cancer model. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041101 |
Targeting the mammalian target of rapamycin (mTOR): a new approach to treating cancer. | British journal of cancer 20041018 |
Synthesis and evaluation of 4-triazolylflavans as new aromatase inhibitors. | Bioorganic & medicinal chemistry letters 20041018 |
Concomitant use of tamoxifen with radiotherapy enhances subcutaneous breast fibrosis in hypersensitive patients. | British journal of cancer 20041004 |
The role of aromatase inhibitors in the adjuvant treatment of breast carcinoma: the M. D. Anderson Cancer Center evidence-based approach. | Cancer 20041001 |
Giving patients a choice improves quality of life: a multi-centre, investigator-blind, randomised, crossover study comparing letrozole with anastrozole. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20041001 |
A method for making estimates of the benefit of the late use of letrozole in patients completing 5 years of tamoxifen. | Clinical breast cancer 20041001 |
Use of estrogen antagonists and aromatase inhibitors in breast cancer and hormonally sensitive tumors of the uterine body. | Current opinion in investigational drugs (London, England : 2000) 20041001 |
New drugs reduce risk of death from breast cancer. | Health news (Waltham, Mass.) 20041001 |
Effects of dehydroepiandrosterone and flutamide on hippocampal CA1 spine synapse density in male and female rats: implications for the role of androgens in maintenance of hippocampal structure. | Endocrinology 20040901 |
A randomized single-blind controlled trial of letrozole as a low-cost IVF protocol in women with poor ovarian response: a preliminary report. | Human reproduction (Oxford, England) 20040901 |
Current developments in hormonal therapy of breast cancer. | Clinical breast cancer 20040901 |
Adjuvant aromatase inhibitors following tamoxifen for early-stage breast cancer in postmenopausal women: what do we really know? | Clinical breast cancer 20040901 |
Aromatase inhibition reduces the dose of gonadotropin required for controlled ovarian hyperstimulation. | Journal of the Society for Gynecologic Investigation 20040901 |
Effects of the steroidal aromatase inhibitor exemestane and the nonsteroidal aromatase inhibitor letrozole on bone and lipid metabolism in ovariectomized rats. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040901 |
A review of adjuvant hormonal therapy in breast cancer. | Endocrine-related cancer 20040901 |
Acute effects of tamoxifen and third-generation aromatase inhibitors on menopausal symptoms of breast cancer patients. | Anti-cancer drugs 20040901 |
Cost utility and budget impact of third-generation aromatase inhibitors for advanced breast cancer: a literature-based model analysis of costs in the Italian National Health Service. | Clinical therapeutics 20040901 |
Fulvestrant: a new type of estrogen receptor antagonist for the treatment of advanced breast cancer. | Drugs of today (Barcelona, Spain : 1998) 20040901 |
Use of aromatase inhibitors in children with short stature. | Pediatric endocrinology reviews : PER 20040901 |
Effects of the antiestrogen tamoxifen and the aromatase inhibitor letrozole on serum hormones and bone characteristics in a preclinical tumor model for breast cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040815 |
Phase III study of letrozole versus tamoxifen as first-line therapy of advanced breast cancer in postmenopausal women: analysis of survival and update of efficacy from the international letrozole breast cancer group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040801 |
An open randomised trial of second-line endocrine therapy in advanced breast cancer: comparison of the Aromatase inhibitors letrozole and anastrozole. | European journal of cancer (Oxford, England : 1990) 20040801 |
Beating breast cancer. | Nursing standard (Royal College of Nursing (Great Britain) : 1987) 20040801 |
Role of aromatase inhibitors in the treatment of breast cancer. | Clinical therapeutics 20040801 |
Cost-effectiveness of letrozole in the treatment of advanced breast cancer. | Expert review of pharmacoeconomics & outcomes research 20040801 |
Chemotherapy of breast cancer-additive anticancerogenic effects by 2-methoxyestradiol? | Life sciences 20040723 |
Her2/neu expression predicts the response to antiaromatase neoadjuvant therapy in primary breast cancer: subgroup analysis from celecoxib antiaromatase neoadjuvant trial. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040715 |
Cost of managing women presenting with stage IV breast cancer in the United Kingdom. | British journal of cancer 20040705 |
The aromatase inhibitor letrozole increases epiphyseal growth plate height and tibial length in peripubertal male mice. | The Journal of endocrinology 20040701 |
Hippocampal synapses depend on hippocampal estrogen synthesis. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040630 |
Comparison of two aromatase inhibitors in women with clomiphene-resistant polycystic ovary syndrome. | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20040601 |
Aromatase inhibitors in the adjuvant setting: bringing the gold to a standard? | Cancer treatment reviews 20040601 |
Aromatase inhibitors in breast cancer. | Endocrine-related cancer 20040601 |
Letrozole (Femara). | Clinical journal of oncology nursing 20040601 |
[Adjuvant treatment of breast cancer by concomitant hormonotherapy and radiotherapy: state of the art]. | Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20040601 |
[Aromatase inhibitors in the adjuvant therapy of breast carcinomas]. | Therapeutische Umschau. Revue therapeutique 20040601 |
Aromatase inhibition in the treatment of advanced breast cancer: is there a relationship between potency and clinical efficacy? | British journal of cancer 20040504 |
Comment on 'Anastrozole (Arimidex) versus tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: survival analysis and updated safety results' by J.-M. Nabholtz et al. | European journal of cancer (Oxford, England : 1990) 20040501 |
The estrogen suppression after sequential treatment with formestane in advanced breast cancer patients. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20040501 |
Estrogen suppression induces papillary gingival overgrowth in pregnant baboons. | Journal of periodontology 20040501 |
NCCN Guideline update: Breast Cancer Version 1.2004. | Journal of the National Comprehensive Cancer Network : JNCCN 20040501 |
Oxytocin receptor is expressed in the penis and mediates an estrogen-dependent smooth muscle contractility. | Endocrinology 20040401 |
[Complete remission obtained with letrozole in a man with metastatic breast cancer]. | La Revue de medecine interne 20040401 |
Does letrozole have any place in adjuvant setting in breast cancer patients with documented hypercoagulability? | American journal of clinical oncology 20040401 |
Aromatase inhibitors: current indications and future prospects for treatment of postmenopausal breast cancer. | Journal of the American Geriatrics Society 20040401 |
Aromatase inhibitors and teratogenesis. | Fertility and sterility 20040401 |
[Adjuvant treatment of breast cancer in 2004. A review of the 8th consensus conference of St. Gallen and new study results]. | Gynakologisch-geburtshilfliche Rundschau 20040401 |
Long-term insurance for breast cancer survivors. | The Johns Hopkins medical letter health after 50 20040401 |
In vivo models for endocrine-dependent breast carcinomas: special considerations of clinical relevance. | European journal of cancer (Oxford, England : 1990) 20040401 |
Aromatase inhibition, testosterone, and seizures. | Epilepsy & behavior : E&B 20040401 |
Characterization of stable human aromatase expressed in E. coli. | Steroids 20040401 |
Clinical trials without ethical review under the spotlight. | Bulletin of the World Health Organization 20040401 |
Therapeutic strategies using the aromatase inhibitor letrozole and tamoxifen in a breast cancer model. | Journal of the National Cancer Institute 20040317 |
Targeting oestrogen to kill the cancer but not the patient. | British journal of cancer 20040308 |
Dehydroepiandrosterone increases hippocampal spine synapse density in ovariectomized female rats. | Endocrinology 20040301 |
Drugs may improve long-term outcomes after breast cancer. | Mayo Clinic health letter (English ed.) 20040301 |
Serum androgen bioactivity in adolescence: a longitudinal study of boys with constitutional delay of puberty. | The Journal of clinical endocrinology and metabolism 20040301 |
New treatment boosts outlook for breast cancer survivors. | Mayo Clinic women's healthsource 20040301 |
Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action. | British journal of cancer 20040301 |
Fulvestrant is an effective and well-tolerated endocrine therapy for postmenopausal women with advanced breast cancer: results from clinical trials. | British journal of cancer 20040301 |
Fulvestrant and the sequential endocrine cascade for advanced breast cancer. | British journal of cancer 20040301 |
Letrozole in breast cancer. | The New England journal of medicine 20040212 |
Letrozole in breast cancer. | The New England journal of medicine 20040212 |
Letrozole in breast cancer. | The New England journal of medicine 20040212 |
Letrozole in breast cancer. | The New England journal of medicine 20040212 |
Letrozole in breast cancer. | The New England journal of medicine 20040212 |
Clinical and endocrine data for goserelin plus anastrozole as second-line endocrine therapy for premenopausal advanced breast cancer. | British journal of cancer 20040209 |
Treatment of severe recurrent endometriosis with an aromatase inhibitor in a young ovariectomised woman. | BJOG : an international journal of obstetrics and gynaecology 20040201 |
Tailoring cancer chemoprevention regimens to the individual. | Journal of cellular biochemistry 20040201 |
Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: a pilot study. | Fertility and sterility 20040201 |
[Controversies in endocrine therapy for breast cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040201 |
Aromatase inhibitors: new endocrine treatment of breast cancer. | Seminars in reproductive medicine 20040201 |
Dynamic contrast enhanced magnetic resonance imaging in monitoring bone metastases in breast cancer patients receiving bisphosphonates and endocrine therapy. | Acta radiologica (Stockholm, Sweden : 1987) 20040201 |
Androgens increase spine synapse density in the CA1 hippocampal subfield of ovariectomized female rats. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040114 |
First-line endocrine treatment of breast cancer: aromatase inhibitor or antioestrogen? | British journal of cancer 20040112 |
Letrozole in postmenopausal women after five years on tamoxifen. | Current oncology reports 20040101 |
Models of breast cancer: is merging human and animal models the future? | Breast cancer research : BCR 20040101 |
Advances in estrogen receptor biology: prospects for improvements in targeted breast cancer therapy. | Breast cancer research : BCR 20040101 |
Sequencing of endocrine therapy in postmenopausal women with advanced breast cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040101 |
Prevention strategies with aromatase inhibitors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040101 |
[Neoadjuvant endocrine therapy for breast cancer: an overview]. | Bulletin du cancer 20040101 |
26th Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, USA, 3-6 December 2003: update on clinical research. | Breast cancer research : BCR 20040101 |
Hormonal therapy in early and advanced breast cancer. | The breast journal 20040101 |
The Letrozole Breast Cancer Trial: clinical implications and remaining questions. | Women's health issues : official publication of the Jacobs Institute of Women's Health 20040101 |
Letrozole-induced polycystic ovaries in the rat: a new model for cystic ovarian disease. | Archives of medical research 20040101 |
Importance of correlative science in advancing hormonal therapy and a new clinical paradigm for neoadjuvant therapy. | Annals of surgical oncology 20040101 |
Role of endocrine therapy in the neoadjuvant surgical setting. | Annals of surgical oncology 20040101 |
Aromatase inhibitors for breast cancer in postmenopausal women. | The oncologist 20040101 |
Changes in vascular endothelial growth factor (VEGF) after chemoendocrine therapy in breast cancer. | European journal of gynaecological oncology 20040101 |
The impact of hormone receptor status on the clinical efficacy of the new-generation aromatase inhibitors: a review of data from first-line metastatic disease trials in postmenopausal women. | The breast journal 20040101 |
Hormonal therapy with letrozole for relapsed epithelial ovarian cancer. Long-term results of a phase II study. | Oncology 20040101 |
Estrogen modulates developmentally regulated gene expression in the fetal baboon liver. | Endocrine 20040101 |
Letrozole: a review of its use in postmenopausal women with breast cancer. | Drugs 20040101 |
Overcoming endocrine therapy resistance by signal transduction inhibition. | The oncologist 20040101 |
Overriding follicle selection in controlled ovarian stimulation protocols: quality vs quantity. | Reproductive biology and endocrinology : RB&E 20040101 |
The physiology of follicle selection. | Reproductive biology and endocrinology : RB&E 20040101 |
[Letrozole vs. placebo after adjuvant tamoxifen in postmenopausal breast cancer. The example of the MA-17 study]. | I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.] 20040101 |
[Letrozole vs. placebo after adjuvant tamoxifen in postmenopausal breast cancer: the MA-17 study]. | I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.] 20040101 |
[The optimal duration of adjuvant therapy in breast cancer: what kind of evidence? Hormone therapy: the example of clinical studies]. | I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.] 20040101 |
[The optimal duration of adjuvant therapy in breast cancer: what kind of evidence? Hormone therapy: what kind of evidence?]. | I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.] 20040101 |
Report on the 4th European Breast Cancer Conference, Hamburg, Germany, 16-20 March 2004. | Breast cancer research : BCR 20040101 |
Patterns of relapse and modalities of treatment of breast cancer: the 'IRIS' Project, a multicenter observational study. | Oncology 20040101 |
Human chorionic gonadotropin administration is associated with high pregnancy rates during ovarian stimulation and timed intercourse or intrauterine insemination. | Reproductive biology and endocrinology : RB&E 20040101 |
Tamoxifen--what next? | The oncologist 20040101 |
Current status of aromatase inhibitors in the management of breast cancer and critique of the NCIC MA-17 trial. | Cancer control : journal of the Moffitt Cancer Center 20040101 |
The activity of letrozole in patients with advanced or recurrent endometrial cancer and correlation with biological markers--a study of the National Cancer Institute of Canada Clinical Trials Group. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20040101 |
New targets for therapy in breast cancer: small molecule tyrosine kinase inhibitors. | Breast cancer research : BCR 20040101 |
New targets for therapy in breast cancer: mammalian target of rapamycin (mTOR) antagonists. | Breast cancer research : BCR 20040101 |
Superiority of letrozole to tamoxifen in the first-line treatment of advanced breast cancer: evidence from metastatic subgroups and a test of functional ability. | The oncologist 20040101 |
Efficacy of first-line letrozole versus tamoxifen as a function of age in postmenopausal women with advanced breast cancer. | The oncologist 20040101 |
Testosterone modulation of seizure susceptibility is mediated by neurosteroids 3alpha-androstanediol and 17beta-estradiol. | Neuroscience 20040101 |
Bone marrow micrometastases and circulating tumor cells: current aspects and future perspectives. | Breast cancer research : BCR 20040101 |
Endocrinology and hormone therapy in breast cancer: aromatase inhibitors versus antioestrogens. | Breast cancer research : BCR 20040101 |
American Society for Clinical Oncology 40th annual meeting, New Orleans, LA, 5-8 June 2004: breast cancer highlights. | Breast cancer research : BCR 20040101 |
Temsirolimus: CCI 779, CCI-779, cell cycle inhibitor-779. | Drugs in R&D 20040101 |
Fulvestrant ('Faslodex')--a new hormonal treatment for advanced breast cancer. | European journal of oncology nursing : the official journal of European Oncology Nursing Society 20040101 |
The scientific value of preoperative studies and how they can be used. | Breast cancer research and treatment 20040101 |
[AIOM Conference 2004. Endocrine therapy and management of patients with bone metastasis of breast cancer]. | Tumori 20040101 |
[Efforts in the individualization of the adjuvant systemic therapy in breast cancer--ASCO, 2004]. | Magyar onkologia 20040101 |
Superiority of letrozole over tamoxifen in the first-line treatment of metastatic breast cancer patients with normal serum Her-2/neu levels: question of tamoxifen resistance. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031215 |
Critics question price of success in halted clinical trial of aromatase inhibitor letrozole. | Journal of the National Cancer Institute 20031203 |
Preoperative systemic treatment: prediction of responsiveness. | Breast (Edinburgh, Scotland) 20031201 |
Effects of letrozole on superovulation with gonadotropins in women undergoing intrauterine insemination. | Fertility and sterility 20031201 |
Comparison of the effects of letrozole and clomiphene citrate on ovarian follicles, endometrium, and hormone levels in the rat. | Fertility and sterility 20031201 |
Letrozole: ovulation or superovulation? | Fertility and sterility 20031201 |
Breast-cancer drug letrozole picks up where tamoxifen leaves off. But we don't know who stands to benefit the most from this follow-up approach. | Health news (Waltham, Mass.) 20031201 |
Top 10 health stories of 2003. | Harvard health letter 20031201 |
Benefit of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer. | Clinical breast cancer 20031201 |
Clinical trials update: Medical management of advanced breast cancer. | Cancer nursing 20031201 |
Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia. | British journal of cancer 20031117 |
Signaling pathways of apoptosis activated by aromatase inhibitors and antiestrogens. | Cancer research 20031115 |
Estrogen-induced neurochemical and electrophysiological changes in the parabrachial nucleus of the male rat. | Brain research 20031114 |
Letrozole after tamoxifen for breast cancer--what is the price of success? | The New England journal of medicine 20031106 |
Beyond tamoxifen--extending endocrine treatment for early-stage breast cancer. | The New England journal of medicine 20031106 |
A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer. | The New England journal of medicine 20031106 |
Economic evaluation of antiaromatase agents in the second-line treatment of metastatic breast cancer. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20031101 |
An open randomised trial of second-line endocrine therapy in advanced breast cancer. comparison of the aromatase inhibitors letrozole and anastrozole. | European journal of cancer (Oxford, England : 1990) 20031101 |
A trial-based cost-effectiveness analysis of letrozole followed by tamoxifen versus tamoxifen followed by letrozole for postmenopausal advanced breast cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20031101 |
Alopecia in a premenopausal breast cancer woman treated with letrozole and triptorelin. | Annals of oncology : official journal of the European Society for Medical Oncology 20031101 |
Response of estrogen receptor-positive intraabdominal fibromatosis to aromatase inhibitor therapy. | Obstetrics and gynecology 20031101 |
Indian drug firm accused of illegal marketing of letrozole. | The Lancet. Oncology 20031101 |
Aromatase inhibitors in breast cancer therapy. | Clinical breast cancer 20031101 |
Synergistic effects of antiprogestins and iNOS or aromatase inhibitors on establishment and maintenance of pregnancy. | Steroids 20031101 |
Clomiphene citrate versus letrozole for ovarian stimulation: a pilot study. | Reproductive biomedicine online 20031101 |
Searching for the next tamoxifen. | U.S. news & world report 20031020 |
Breast cancer's 'new era'. | Newsweek 20031020 |
Doctors in India prescribe unapproved fertility drug. | BMJ (Clinical research ed.) 20031004 |
Indian firm caught marketing anticancer drug for fertility. | Lancet (London, England) 20031004 |
Letrozole inhibits tumor proliferation more effectively than tamoxifen independent of HER1/2 expression status. | Cancer research 20031001 |
The pharmacology of letrozole. | The Journal of steroid biochemistry and molecular biology 20031001 |
Hormonal effects of aromatase inhibitors: focus on premenopausal effects and interaction with tamoxifen. | The Journal of steroid biochemistry and molecular biology 20030901 |
The intratumoral aromatase model: studies with aromatase inhibitors and antiestrogens. | The Journal of steroid biochemistry and molecular biology 20030901 |
Letrozole versus tamoxifen in the treatment of advanced breast cancer and as neoadjuvant therapy. | The Journal of steroid biochemistry and molecular biology 20030901 |
Neoadjuvant tamoxifen and aromatase inhibitors: comparisons and clinical outcomes. | The Journal of steroid biochemistry and molecular biology 20030901 |
Neoadjuvant comparisons of aromatase inhibitors and tamoxifen: pretreatment determinants of response and on-treatment effect. | The Journal of steroid biochemistry and molecular biology 20030901 |
Aromatase inhibitors versus tamoxifen for management of postmenopausal breast cancer in the advanced disease and neoadjuvant settings. | The Journal of steroid biochemistry and molecular biology 20030901 |
Novel treatment of short stature with aromatase inhibitors. | The Journal of steroid biochemistry and molecular biology 20030901 |
An integrated view of aromatase and its inhibition. | The Journal of steroid biochemistry and molecular biology 20030901 |
Celecoxib anti-aromatase neoadjuvant (CAAN) trial for locally advanced breast cancer: preliminary report. | The Journal of steroid biochemistry and molecular biology 20030901 |
Role of steroid sulfatase in local formation of estrogen in post-menopausal breast cancer patients. | The Journal of steroid biochemistry and molecular biology 20030901 |
Use of letrozole as a chemopreventive agent in aromatase overexpressing transgenic mice. | The Journal of steroid biochemistry and molecular biology 20030901 |
Local estrogen formation by nontumoral, cirrhotic, and malignant human liver tissues and cells. | Cancer research 20030815 |
Estrogen and antiestrogen effects on neonatal ovine uterine development. | Biology of reproduction 20030801 |
Aromatase inhibition reduces gonadotrophin dose required for controlled ovarian stimulation in women with unexplained infertility. | Human reproduction (Oxford, England) 20030801 |
The dawning of the non-cancer uses of aromatase inhibitors in gynaecology. | Human reproduction (Oxford, England) 20030801 |
The current status of aromatase inhibitors in the management of breast cancer. | The Surgical clinics of North America 20030801 |
Development of aromatase inhibitors and their pharmacologic profile. | American journal of clinical oncology 20030801 |
A comparison of the efficacy of aromatase inhibitors in second-line treatment of metastatic breast cancer. | American journal of clinical oncology 20030801 |
Applicability of the intratumor aromatase preclinical model to predict clinical trial results with endocrine therapy. | American journal of clinical oncology 20030801 |
Emerging role of aromatase inhibitors in the adjuvant setting. | American journal of clinical oncology 20030801 |
Role of biologic markers in patient selection and application to disease prevention. | American journal of clinical oncology 20030801 |
Examining quality of life issues in relation to endocrine therapy for breast cancer. | American journal of clinical oncology 20030801 |
Effects of suppression of estrogen action by the p450 aromatase inhibitor letrozole on bone mineral density and bone turnover in pubertal boys. | The Journal of clinical endocrinology and metabolism 20030801 |
Should aromatase inhibitors replace tamoxifen? | Drug and therapeutics bulletin 20030801 |
Aromatase inhibitors: mechanism of action and role in the treatment of breast cancer. | Seminars in oncology 20030801 |
Aromatase inhibitor development and hormone therapy: a perspective. | Seminars in oncology 20030801 |
Pharmacokinetics of third-generation aromatase inhibitors. | Seminars in oncology 20030801 |
The role of aromatase inhibitors in the treatment of metastatic breast cancer. | Seminars in oncology 20030801 |
Aromatase inhibitors in early breast cancer treatment. | Seminars in oncology 20030801 |
Hormonal therapy: introduction. | Breast (Edinburgh, Scotland) 20030801 |
Challenges in the endocrine management of breast cancer. | Breast (Edinburgh, Scotland) 20030801 |
Biological response to hormonal manipulation in oestrogen receptor positive ductal carcinoma in situ of the breast. | British journal of cancer 20030721 |
First dual aromatase-steroid sulfatase inhibitors. | Journal of medicinal chemistry 20030717 |
Is there a benefit by the sequence anastrozole-formestane for postmenopausal metastatic breast cancer women? | The Journal of steroid biochemistry and molecular biology 20030701 |
[Hormone therapy, chemotherapy and immunotherapy in breast carcinoma. The best strategy for your patient]. | MMW Fortschritte der Medizin 20030612 |
Phase III study of letrozole versus tamoxifen as first-line therapy of advanced breast cancer in postmenopausal women: analysis of survival and update of efficacy from the International Letrozole Breast Cancer Group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030601 |
New approaches to the understanding of tamoxifen action and resistance. | Endocrine-related cancer 20030601 |
Cost utility analysis of first-line hormonal therapy in advanced breast cancer: comparison of two aromatase inhibitors to tamoxifen. | American journal of clinical oncology 20030601 |
Serum HER-2/neu and response to the aromatase inhibitor letrozole versus tamoxifen. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030515 |
Postmenopausal women who progress on fulvestrant ('Faslodex') remain sensitive to further endocrine therapy. | Breast cancer research and treatment 20030501 |
Durable remission of leptomeningeal metastasis of breast cancer with letrozole: a case report and implications of biomarkers on treatment selection. | Japanese journal of clinical oncology 20030501 |
The role of aromatase inhibitors in early breast cancer. | Current treatment options in oncology 20030401 |
Expression of functional estrogen receptors in human fetal male external genitalia. | The Journal of clinical endocrinology and metabolism 20030401 |
Update on the current use of hormonals as therapy in advanced breast cancer. | Anti-cancer drugs 20030401 |
[Present and future of adjuvant hormone therapy in breast cancer: clinical evidence and clinical trials]. | Revista clinica espanola 20030401 |
Aromatase inhibitors for treatment of postmenopausal patients with breast cancer. | Expert review of anticancer therapy 20030401 |
Letrozole as a potent inhibitor of cell proliferation and expression of metalloproteinases (MMP-2 and MMP-9) by human epithelial breast cancer cells. | International journal of cancer 20030320 |
Pathological features of breast cancer response following neoadjuvant treatment with either letrozole or tamoxifen. | European journal of cancer (Oxford, England : 1990) 20030301 |
Inhibition of IL-6+IL-6 soluble receptor-stimulated aromatase activity by the IL-6 antagonist, Sant 7, in breast tissue-derived fibroblasts. | British journal of cancer 20030224 |
[Treatment of advanced metastatic breast cancer with exemestane, a multicenter randomized controlled study of 195 cases]. | Zhonghua yi xue za zhi 20030210 |
Update on clinical role of tamoxifen. | Current opinion in obstetrics & gynecology 20030201 |
Double-blind randomised trial comparing the non-steroidal aromatase inhibitors letrozole and fadrozole in postmenopausal women with advanced breast cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20030101 |
Fetal lung maturation in estrogen-deprived baboons. | The Journal of clinical endocrinology and metabolism 20030101 |
Predictions from a preclinical model: studies of aromatase inhibitors and antiestrogens. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030101 |
Pharmacology and pharmacokinetics of the newer generation aromatase inhibitors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030101 |
Clinical differences among the aromatase inhibitors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030101 |
25th Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, USA, 10-14 December 2002 Update on clinical research. | Breast cancer research : BCR 20030101 |
A stochastic economic evaluation of letrozole versus tamoxifen as a first-line hormonal therapy: for advanced breast cancer in postmenopausal patients. | PharmacoEconomics 20030101 |
Para/autocrine regulation of estrogen receptors in hippocampal neurons. | Hippocampus 20030101 |
A roundtable discussion of aromatase inhibitors as therapy for breast cancer. | The breast journal 20030101 |
Hormonal therapy in postmenopausal women with breast cancer. | Oncology 20030101 |
The future of cytotoxic therapy: selective cytotoxicity based on biology is the key. | Breast cancer research : BCR 20030101 |
Role of oxytocin in the ejaculatory process. | Journal of endocrinological investigation 20030101 |
Advances in endocrine treatments for postmenopausal women with metastatic and early breast cancer. | The oncologist 20030101 |
Safety issues surrounding the use of aromatase inhibitors in breast cancer. | Expert opinion on drug safety 20030101 |
Advances in breast cancer treatment and prevention: preclinical studies on aromatase inhibitors and new selective estrogen receptor modulators (SERMs). | Breast cancer research : BCR 20030101 |
[Perspectives for the hormonal therapy of breast cancer]. | Magyar onkologia 20030101 |
[Aromatase inhibitors--theoretical concept and present experiences in the treatment of endometriosis]. | Zentralblatt fur Gynakologie 20030101 |
Estrogen, progesterone and epithelial ovarian cancer. | Reproductive biology and endocrinology : RB&E 20030101 |
The management of infertility associated with polycystic ovary syndrome. | Reproductive biology and endocrinology : RB&E 20030101 |
[Endocrine therapy of causation: role of aromatase inhibitors in breast cancer]. | Tumori 20030101 |
Fulvestrant ('Faslodex')--a new treatment option for patients progressing on prior endocrine therapy. | Endocrine-related cancer 20021201 |
Neoadjuvant therapy of endometrial cancer with the aromatase inhibitor letrozole: endocrine and clinical effects. | European journal of obstetrics, gynecology, and reproductive biology 20021115 |
Expression and purification of a recombinant form of human aromatase from Escherichia coli. | Biochemical pharmacology 20021101 |
Developmental, estrogen induced infravesical obstruction is reversible in adult male rodents. | The Journal of urology 20021101 |
Estrogens, but not androgens, regulate expression and functional activity of oxytocin receptor in rabbit epididymis. | Endocrinology 20021101 |
Selective aromatase inhibition for patients with androgen-independent prostate carcinoma. | Cancer 20021101 |
An overview of the pharmacology and pharmacokinetics of the newer generation aromatase inhibitors anastrozole, letrozole, and exemestane. | Cancer 20021101 |
Letrozole's superiority over progestins and tamoxifen challenges standards of care in endocrine therapy for metastatic breast cancer. | European journal of cancer (Oxford, England : 1990) 20021101 |
Neoadjuvant endocrine therapy of breast cancer: a surgical perspective. | European journal of cancer (Oxford, England : 1990) 20021101 |
Anastrozole ('Arimidex') blocks oestrogen synthesis both peripherally and within the breast in postmenopausal women with large operable breast cancer. | British journal of cancer 20021021 |
Developmental regulation of baboon fetal ovarian maturation by estrogen. | Biology of reproduction 20021001 |
New generation aromatase inhibitors--from the advanced to the adjuvant setting. | Breast cancer research and treatment 20021001 |
Sequencing of endocrine therapies in breast cancer--integration of recent data. | Breast cancer research and treatment 20021001 |
The evolving role of aromatase inhibitors in breast cancer. | International journal of clinical oncology 20021001 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20021001 |
Reversible pancytopenia caused by oral letrozole assumption in a patient with recurrent breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020901 |
A randomized double-blind comparison of the effects of clomiphene citrate and the aromatase inhibitor letrozole on ovulatory function in normal women. | Fertility and sterility 20020801 |
American Society of Clinical Oncology technology assessment on the use of aromatase inhibitors as adjuvant therapy for women with hormone receptor-positive breast cancer: status report 2002. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020801 |
Signaling through estrogen receptors modulates telomerase activity in human prostate cancer. | The Journal of clinical investigation 20020715 |
Endocrine effects of nonsteroidal aromatase inhibitors and their clinical impact. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020701 |
Effects of the aromatase inhibitor letrozole on normal breast epithelial cell proliferation and metabolic indices in postmenopausal women: a pilot study for breast cancer prevention. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20020701 |
Human ejaculated spermatozoa contain active P450 aromatase. | The Journal of clinical endocrinology and metabolism 20020701 |
Genetic or enzymatic disruption of aromatase inhibits the growth of ectopic uterine tissue. | The Journal of clinical endocrinology and metabolism 20020701 |
CA125 response is associated with estrogen receptor expression in a phase II trial of letrozole in ovarian cancer: identification of an endocrine-sensitive subgroup. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020701 |
The effect of second-line antiestrogen therapy on breast tumor growth after first-line treatment with the aromatase inhibitor letrozole: long-term studies using the intratumoral aromatase postmenopausal breast cancer model. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020701 |
Direct in vitro effects of androgens and estrogens on ob gene expression and leptin secretion in human adipose tissue. | Endocrine 20020701 |
[Antiestrogen therapy in the treatment of breast neoplasms]. | Minerva ginecologica 20020601 |
Letrozole for the management of breast cancer. | Expert review of anticancer therapy 20020601 |
Exemestane: a potent irreversible aromatase inactivator and a promising advance in breast cancer treatment. | Expert review of anticancer therapy 20020601 |
[Blood and tissue eosinophilia, mistletoe lectin antibodies and quality of life in a breast cancer patient undergoing intratumoral and subcutaneous mistletoe therapy]. | Forschende Komplementarmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine 20020601 |
Recent advances in aromatase inhibitor therapy for breast cancer. | Seminars in oncology 20020601 |
Letrozole in the treatment of breast cancer. | Expert opinion on pharmacotherapy 20020501 |
[CGS20267 (Letrozole), a new aromatase inhibitor: late phase II study for postmenopausal women with advanced or recurrent breast cancer (no. 1)--investigation of recommended clinical dose CGS20267 Study Group]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020501 |
[CGS20267 (Letrozole), a new aromatase inhibitor: late phase II study in postmenopausal women with advanced or recurrent breast cancer (no. 2)--evaluation of efficacy and safety at the recommended clinical dose CGS20267 Study Group]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020501 |
Aromatase inhibition improves ovarian response to follicle-stimulating hormone in poor responders. | Fertility and sterility 20020401 |
New breast cancer drugs expand treatment options. | Harvard women's health watch 20020401 |
[CGS 20267 (Letrozole), a new aromatase inhibitor: early phase II study for postmenopausal women with advanced breast cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020401 |
Short-term effects of anastrozole treatment on insulin-like growth factor system in postmenopausal advanced breast cancer patients. | The Journal of steroid biochemistry and molecular biology 20020401 |
Antiaromatase agents: evolving role in adjuvant therapy. | Clinical breast cancer 20020401 |
[The role of aromatase inhibitors in the treatment of breast neoplasms. An evaluation of clinical efficacy and the tolerability profile]. | Minerva ginecologica 20020401 |
Aromatase inhibitors in breast cancer therapy. | Expert review of anticancer therapy 20020401 |
Detection of aromatase inhibitors in vitro using rat ovary microsomes. | Toxicology letters 20020324 |
Elevated serum Her-2/neu level predicts decreased response to hormone therapy in metastatic breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020315 |
Aromatase inhibitors in breast cancer. | Trends in endocrinology and metabolism: TEM 20020301 |
The role of sex steroids in the regulation of insulin sensitivity and serum lipid concentrations during male puberty: a prospective study with a P450-aromatase inhibitor. | European journal of endocrinology 20020301 |
Approval summary: letrozole in the treatment of postmenopausal women with advanced breast cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020301 |
Current status and future innovations of hormonal agents, chemotherapy and investigational agents in endometrial cancer. | Current opinion in obstetrics & gynecology 20020201 |
Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020201 |
Superior efficacy of letrozole versus tamoxifen as first-line therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020201 |
[Superiority of letrozole compared with tamoxifen as first line therapy of postmenopausal women with advanced breast cancer: results of a phase III study of the International Letrozole Breast Cancer Group]. | Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20020201 |
[Aromatase inhibitors of the 3rd generation. What can the 'pill against breast cancer' really do?]. | MMW Fortschritte der Medizin 20020131 |
[Growth rate can be manipulated. Estrogen production in pubertal boys can be blocked by an aromatase inhibitor]. | Lakartidningen 20020117 |
Role of low levels of endogenous estrogen in regulation of bone resorption in late postmenopausal women. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020101 |
Reproductive changes in male rats treated perinatally with an aromatase inhibitor. | Pharmacology, biochemistry, and behavior 20020101 |
Tamoxifen resistant and refractory breast cancer: the value of aromatase inhibitors. | Drugs 20020101 |
Anti-aromatase agents in the treatment and prevention of breast cancer. | Cancer control : journal of the Moffitt Cancer Center 20020101 |
Endocrine and clinical endpoints of exemestane as neoadjuvant therapy. | Cancer control : journal of the Moffitt Cancer Center 20020101 |
Recent advances in breast cancer (the Twenty-fourth San Antonio Breast Cancer Symposium, December, 2001). | Current medical research and opinion 20020101 |
Novel treatment of delayed male puberty with aromatase inhibitors. | Hormone research 20020101 |
Estrogen as therapy for breast cancer. | Breast cancer research : BCR 20020101 |
Defining the galaxy of gene expression in breast cancer. | Breast cancer research : BCR 20020101 |
The impact of hormonal treatments on quality of life of patients with metastatic breast cancer. | Clinical therapeutics 20020101 |
Evolving uses of hormonal agents for breast cancer therapy. | Clinical therapeutics 20020101 |
Sequencing of hormonal therapy in postmenopausal women with metastatic breast cancer. | Clinical therapeutics 20020101 |
Efficacy and economics of hormonal therapies for advanced breast cancer. | Drugs & aging 20020101 |
Tumour Fas ligand:Fas ratio greater than 1 is an independent marker of relative resistance to tamoxifen therapy in hormone receptor positive breast cancer. | Breast cancer research : BCR 20020101 |
Anti-tumor effects of letrozole. | Cancer investigation 20020101 |
Current role of endocrine therapy in the management of breast cancer. | Breast cancer (Tokyo, Japan) 20020101 |
Aromatase inhibitors in breast cancer: an update. | Cancer control : journal of the Moffitt Cancer Center 20020101 |
New breast cancer drug. | U.S. news & world report 20011224 |
Letrozole in second-line therapy of advanced breast cancer: more questions than answers. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20011201 |
False shortening of time to progression in letrozole 2.5-mg dose? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20011201 |
High dehydroepiandrosterone-sulfate predicts breast cancer progression during new aromatase inhibitor therapy and stimulates breast cancer cell growth in tissue culture: a renewed role for adrenalectomy. | Surgery 20011201 |
Aromatase overexpression transgenic mice model: cell type specific expression and use of letrozole to abrogate mammary hyperplasia without affecting normal physiology. | The Journal of steroid biochemistry and molecular biology 20011201 |
Aromatase and COX-2 expression in human breast cancers. | The Journal of steroid biochemistry and molecular biology 20011201 |
Comparative clinical pharmacology and pharmacokinetic interactions of aromatase inhibitors. | The Journal of steroid biochemistry and molecular biology 20011201 |
Local endocrine effects of aromatase inhibitors within the breast. | The Journal of steroid biochemistry and molecular biology 20011201 |
Biological and clinical effects of aromatase inhibitors in neoadjuvant therapy. | The Journal of steroid biochemistry and molecular biology 20011201 |
A summary of second-line randomized studies of aromatase inhibitors. | The Journal of steroid biochemistry and molecular biology 20011201 |
Adjuvant trials of aromatase inhibitors: determining the future landscape of adjuvant endocrine therapy. | The Journal of steroid biochemistry and molecular biology 20011201 |
Where do selective estrogen receptor modulators (SERMs) and aromatase inhibitors (AIs) now fit into breast cancer treatment algorithms? | The Journal of steroid biochemistry and molecular biology 20011201 |
17alpha-methyl testosterone is a competitive inhibitor of aromatase activity in Jar choriocarcinoma cells and macrophage-like THP-1 cells in culture. | The Journal of steroid biochemistry and molecular biology 20011201 |
The role of tamoxifen and aromatase inhibitors/inactivators in postmenopausal patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20011201 |
Are differences in the available aromatase inhibitors and inactivators significant? | Clinical cancer research : an official journal of the American Association for Cancer Research 20011201 |
Neoadjuvant endocrine therapy for breast cancer: medical perspectives. | Clinical cancer research : an official journal of the American Association for Cancer Research 20011201 |
Preliminary data from ongoing adjuvant aromatase inhibitor trials. | Clinical cancer research : an official journal of the American Association for Cancer Research 20011201 |
Future use of selective estrogen receptor modulators and aromatase inhibitors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20011201 |
Promising results for Arimidex and Femara. | Expert review of anticancer therapy 20011201 |
Pre-operative endocrine therapy for postmenopausal women: when and why? | Annals of oncology : official journal of the European Society for Medical Oncology 20011101 |
Preoperative treatment of postmenopausal breast cancer patients with letrozole: A randomized double-blind multicenter study. | Annals of oncology : official journal of the European Society for Medical Oncology 20011101 |
Formestane, a steroidal aromatase inhibitor after failure of non-steroidal aromatase inhibitors (anastrozole and letrozole): is a clinical benefit still achievable? | Annals of oncology : official journal of the European Society for Medical Oncology 20011101 |
Role of hormones in puberty. | Lancet (London, England) 20011027 |
Aromatase inhibitors and inactivators in breast cancer. | BMJ (Clinical research ed.) 20011020 |
Developmental maturation of primate placental trophoblast: placental cytosolic and secretory phospholipase A2 expression after estrogen suppression of baboons. | Prostaglandins & other lipid mediators 20011001 |
Aromatase inhibitors: treatment of advanced breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20011001 |
Inhibition of P450 aromatase enhances gonadotropin secretion in early and midpubertal boys: evidence for a pituitary site of action of endogenous E. | The Journal of clinical endocrinology and metabolism 20011001 |
Role of anti-aromatase agents in postmenopausal advanced breast cancer. | Cancer chemotherapy and pharmacology 20011001 |
Sex reversal and aromatase in the European pond turtle: treatment with letrozole after the thermosensitive period for sex determination. | The Journal of experimental zoology 20010915 |
Use of ErbB-1 and ErbB-2 to select endocrine therapy for breast cancer: will it play in Peoria? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010915 |
Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: evidence from a phase III randomized trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010915 |
Advances in aromatase inhibition: clinical efficacy and tolerability in the treatment of breast cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010901 |
Effect of letrozole on the lipid profile in postmenopausal women with breast cancer. | European journal of cancer (Oxford, England : 1990) 20010801 |
Endometrial stromal sarcoma: objective response to letrozole. | Gynecologic oncology 20010801 |
Nonsteroidal and steroidal aromatase inhibitors in breast cancer. | Oncology (Williston Park, N.Y.) 20010801 |
Exemestane: new preparation. No tangible advance in metastatic breast cancer after tamoxifen failure. | Prescrire international 20010801 |
Phase III, multicenter, double-blind, randomized study of letrozole, an aromatase inhibitor, for advanced breast cancer versus megestrol acetate. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010715 |
[Developments of hormonal agents for breast cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20010701 |
[Endocrine therapy for advanced or recurrent breast cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20010701 |
Effect of age and single versus multiple dose pharmacokinetics of letrozole (Femara) in breast cancer patients. | Biopharmaceutics & drug disposition 20010701 |
Use of a specific aromatase inhibitor in delayed puberty. | Lancet (London, England) 20010602 |
A specific aromatase inhibitor and potential increase in adult height in boys with delayed puberty: a randomised controlled trial. | Lancet (London, England) 20010602 |
Endocrine therapy in the treatment of metastatic breast cancer. | Seminars in oncology 20010601 |
Superior efficacy of letrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer: results of a phase III study of the International Letrozole Breast Cancer Group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010515 |
Aromatase regulation and breast cancer. | Clinical endocrinology 20010501 |
Aromatase inhibition and antiestrogen therapy in early breast cancer treatment and chemoprevention. | Oncology (Williston Park, N.Y.) 20010501 |
Developmental regulation of morphological differentiation of placental villous trophoblast in the baboon. | Placenta 20010401 |
Metastatic breast cancer: understanding current management options. | Oncology nursing forum 20010401 |
Letrozole as primary medical therapy for locally advanced and large operable breast cancer. | Breast cancer research and treatment 20010401 |
Importance of local aromatase activity in hormone-dependent breast cancer: a review. | Breast (Edinburgh, Scotland) 20010401 |
From the Food and Drug Administration. | JAMA 20010307 |
FDA panel recommends two new cancer drugs for approval. | Journal of the National Cancer Institute 20010207 |
Use of an aromatase inhibitor for induction of ovulation in patients with an inadequate response to clomiphene citrate. | Fertility and sterility 20010201 |
The Twenty-third Annual San Antonio Breast Cancer Symposium. | Current medical research and opinion 20010101 |
Update on endocrine aspects of breast cancer: report from the 23rd San Antonio Breast Cancer Symposium, San Antonio, Texas, USA, 6-9 December 2000. | Breast cancer research : BCR 20010101 |
[Modern approaches to hormone therapy of breast cancer as a reflection of pathogenesis of the disease]. | Voprosy onkologii 20010101 |
Intracellular aromatase and its relevance to the pharmacological efficacy of aromatase inhibitors. | The Journal of steroid biochemistry and molecular biology 20010101 |
Femara approved as first-line breast cancer therapy. | FDA consumer 20010101 |
Aromatase, aromatase inhibitors, and breast cancer. | American journal of therapeutics 20010101 |
Flare and tumor lysis syndrome with atypical features after letrozole therapy in advanced breast cancer. A case report. | Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna 20010101 |
Huge response to letrozole in inoperable T4 breast cancer: a case report. | La Clinica terapeutica 20010101 |
[Neoadjuvant use of the aromatase inhibitor letrozole in uterine cancer: endocrine and clinical effects]. | Voprosy onkologii 20010101 |
Third-generation aromatase inhibitors in the treatment of advanced breast cancer. | Breast cancer (Tokyo, Japan) 20010101 |
Aromatase and aromatase inhibitors. | Breast cancer (Tokyo, Japan) 20010101 |
Treatment of delayed male puberty: efficacy of aromatase inhibition. | Journal of pediatric endocrinology & metabolism : JPEM 20010101 |
Aromatase inhibitors. | Current medical research and opinion 20010101 |
Arimidex: a potent and selective fourth-generation aromatase inhibitor. | Breast cancer research and treatment 19940101 |
Highly selective inhibition of estrogen biosynthesis by CGS 20267, a new non-steroidal aromatase inhibitor. | The Journal of steroid biochemistry and molecular biology 19901220 |