(E)-3-((4-(tert-Butyl)phenyl)sulfonyl)acrylonitrile
| Title | Journal |
|---|---|
| Elevated IL-1β expression induces invasiveness of triple negative breast cancer cells and is suppressed by zerumbone. | Chemico-biological interactions 20161025 |
| Hexabromocyclododecane and tetrabromobisphenol A alter secretion of interferon gamma (IFN-γ) from human immune cells. | Archives of toxicology 20160701 |
| Identification of compounds that modulate retinol signaling using a cell-based qHTS assay. | Toxicology in vitro : an international journal published in association with BIBRA 20160401 |
| Tributyltin alters secretion of interleukin 1 beta from human immune cells. | Journal of applied toxicology : JAT 20150801 |
| Quercetin-3-O-(2″-galloyl)-α-L-rhamnopyranoside attenuates cholesterol oxidation product-induced apoptosis by suppressing NF-κB-mediated cell death process in differentiated PC12 cells. | Naunyn-Schmiedeberg's archives of pharmacology 20150801 |
| Mitochondrial dysfunction promotes and aggravates the inflammatory response in normal human synoviocytes. | Rheumatology (Oxford, England) 20140701 |
| FSL-1 induces MMP-9 production through TLR-2 and NF-κB /AP-1 signaling pathways in monocytic THP-1 cells. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20140101 |
| Inhibition of HIV-1 replication by a tricyclic coumarin GUT-70 in acutely and chronically infected cells. | Bioorganic & medicinal chemistry letters 20130201 |
| T-2 toxin enhances catabolic activity of hypertrophic chondrocytes through ROS-NF-κB-HIF-2α pathway. | Toxicology in vitro : an international journal published in association with BIBRA 20121001 |
| Identification of UV-protective activators of nuclear factor erythroid-derived 2-related factor 2 (Nrf2) by combining a chemical library screen with computer-based virtual screening. | The Journal of biological chemistry 20120921 |
| Mitochondrial dysfunction increases inflammatory responsiveness to cytokines in normal human chondrocytes. | Arthritis and rheumatism 20120901 |
| Motorcycle exhaust particles up-regulate expression of vascular adhesion molecule-1 and intercellular adhesion molecule-1 in human umbilical vein endothelial cells. | Toxicology in vitro : an international journal published in association with BIBRA 20120601 |
| Effects of cobalt chloride on nitric oxide and cytokines/chemokines production in microglia. | International immunopharmacology 20120501 |
| Zinc oxide nanoparticles-induced intercellular adhesion molecule 1 expression requires Rac1/Cdc42, mixed lineage kinase 3, and c-Jun N-terminal kinase activation in endothelial cells. | Toxicological sciences : an official journal of the Society of Toxicology 20120301 |
| Synthesis and biological evaluation of sulfonyl acrylonitriles as novel inhibitors to peritoneal carcinomatosis. | Bioorganic & medicinal chemistry letters 20120301 |
| Contact sensitizers modulate the arachidonic acid metabolism of PMA-differentiated U-937 monocytic cells activated by LPS. | Toxicology and applied pharmacology 20111001 |
| A novel dithiol amide CB3 attenuates allergic airway disease through negative regulation of p38 mitogen-activated protein kinase. | American journal of respiratory and critical care medicine 20110415 |
| NF-κB inhibition compromises cardiac fibroblast viability under hypoxia. | Experimental cell research 20110415 |
| Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism. | Cell death & disease 20110401 |
| IgE-dependent sensitization increases responsiveness to LPS but does not modify development of endotoxin tolerance in mast cells. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110101 |
| 7-ketocholesterol induces apoptosis in differentiated PC12 cells via reactive oxygen species-dependent activation of NF-κB and Akt pathways. | Neurochemistry international 20110101 |
| Effect of inhibition of the ubiquitin-proteasome-system and IκB kinase on airway inflammation and hyperresponsiveness in a murine model of asthma. | International journal of immunopathology and pharmacology 20110101 |
| Thromboxane synthase suppression induces lung cancer cell apoptosis via inhibiting NF-κB. | Experimental cell research 20101210 |
| Phosphoinositide 3-kinase δ inhibitor suppresses interleukin-17 expression in a murine asthma model. | The European respiratory journal 20101201 |
| Mechanisms of IL-12 synthesis by human dendritic cells treated with the chemical sensitizer NiSO4. | Journal of immunology (Baltimore, Md. : 1950) 20100701 |
| High glucose promotes intracellular lipid accumulation in vascular smooth muscle cells by impairing cholesterol influx and efflux balance. | Cardiovascular research 20100401 |
| Cytochrome P450 1A1 gene regulation by UVB involves crosstalk between the aryl hydrocarbon receptor and nuclear factor kappaB. | Chemico-biological interactions 20100330 |
| Hyaluronan inhibits prostaglandin E2 production via CD44 in U937 human macrophages. | The Tohoku journal of experimental medicine 20100301 |
| Correlation of NF-kappaB signal pathway with tumor metastasis of human head and neck squamous cell carcinoma. | BMC cancer 20100101 |
| Irreversibly glycated LDL induce oxidative and inflammatory state in human endothelial cells; added effect of high glucose. | Biochemical and biophysical research communications 20091218 |
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
| Differential regulation of HIF-1alpha isoforms in murine macrophages by TLR4 and adenosine A(2A) receptor agonists. | Journal of leukocyte biology 20090901 |
| Pre-B cell colony enhancing factor (PBEF)/visfatin induces secretion of MCP-1 in human endothelial cells: role in visfatin-induced angiogenesis. | Atherosclerosis 20090701 |
| TNF-alpha reduces the level of Staphylococcus epidermidis internalization by bovine endothelial cells. | FEMS microbiology letters 20090301 |
| Systemic inhibition of NF-kappaB activation protects from silicosis. | PloS one 20090101 |
| Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells. | Breast cancer research and treatment 20081101 |
| 17-Beta estradiol and hydroxyestradiols interact via the NF-kappa B pathway to elevate cyclooxygenase 2 expression and prostaglandin E2 secretion in human bronchial epithelial cells. | Toxicological sciences : an official journal of the Society of Toxicology 20080801 |
| Flagellin and lipopolysaccharide up-regulation of IL-6 and CXCLi2 gene expression in chicken heterophils is mediated by ERK1/2-dependent activation of AP-1 and NF-kappaB signaling pathways. | Innate immunity 20080801 |
| JNK- and IkappaB-dependent pathways regulate MCP-1 but not adiponectin release from artificially hypertrophied 3T3-L1 adipocytes preloaded with palmitate in vitro. | American journal of physiology. Endocrinology and metabolism 20080501 |
| Internalization of Staphylococcus aureus by bovine endothelial cells is associated with the activity state of NF-kappaB and modulated by the pro-inflammatory cytokines TNF-alpha and IL-1beta. | Scandinavian journal of immunology 20080201 |
| High glucose enhances lipopolysaccharide-stimulated CD14 expression in U937 mononuclear cells by increasing nuclear factor kappaB and AP-1 activities. | The Journal of endocrinology 20080101 |
| Implications of the involvement of the endoplasmic reticulum stress pathway in drug-induced apoptosis. | Anticancer research 20080101 |
| Targeting the nuclear factor-kappaB rescue pathway has promising future in human renal cell carcinoma therapy. | Cancer research 20071215 |
| Nitric oxide dysregulates adipocytokine expression in 3T3-L1 adipocytes. | Biochemical and biophysical research communications 20071207 |
| PTEN down-regulates IL-17 expression in a murine model of toluene diisocyanate-induced airway disease. | Journal of immunology (Baltimore, Md. : 1950) 20071115 |
| Inhibitors of NF-kappaB derived from thalidomide. | Bioorganic & medicinal chemistry letters 20071101 |
| CGRP, PACAP, and VIP modulate Langerhans cell function by inhibiting NF-kappaB activation. | The Journal of investigative dermatology 20071001 |
| NF-kappaB plays a major role in the maturation of human dendritic cells induced by NiSO(4) but not by DNCB. | Toxicological sciences : an official journal of the Society of Toxicology 20071001 |
| Cytotoxicity of NF-kappaB inhibitors Bay 11-7085 and caffeic acid phenethyl ester to Ramos and other human B-lymphoma cell lines. | Experimental hematology 20071001 |
| Application of the nuclear factor-kappaB inhibitor BAY 11-7085 for the treatment of endometriosis: an in vitro study. | American journal of physiology. Endocrinology and metabolism 20070701 |
| PAR-2 activation regulates IL-8 and GRO-alpha synthesis by NF-kappaB, but not RANTES, IL-6, eotaxin or TARC expression in nasal epithelium. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20070701 |
| Role of ROS and MAPK in TPA-induced ICAM-1 expression in the myeloid ML-1 cell line. | Journal of cellular biochemistry 20070301 |
| An environmental quinoid polycyclic aromatic hydrocarbon, acenaphthenequinone, modulates cyclooxygenase-2 expression through reactive oxygen species generation and nuclear factor kappa B activation in A549 cells. | Toxicological sciences : an official journal of the Society of Toxicology 20070201 |
| TNF-alpha induces transient resistance to Fas-induced apoptosis in eosinophilic acute myeloid leukemia cells. | Cellular & molecular immunology 20070201 |
| Cysteinyl leukotriene upregulates IL-11 expression in allergic airway disease of mice. | The Journal of allergy and clinical immunology 20070101 |
| Understanding interactions between and among apoptosis inducing pathways in tumor cells. | In vivo (Athens, Greece) 20070101 |
| Modulation of airway remodeling and airway inflammation by peroxisome proliferator-activated receptor gamma in a murine model of toluene diisocyanate-induced asthma. | Journal of immunology (Baltimore, Md. : 1950) 20061015 |
| Diverse effects of zinc on NF-kappaB and AP-1 transcription factors: implications for prostate cancer progression. | Carcinogenesis 20061001 |
| Angiotensin II induces monocyte chemoattractant protein-1 expression via a nuclear factor-kappaB-dependent pathway in rat preadipocytes. | American journal of physiology. Endocrinology and metabolism 20061001 |
| Bile acids induce adhesion molecule expression in endothelial cells through activation of reactive oxygen species, NF-kappaB, and p38. | American journal of physiology. Heart and circulatory physiology 20060801 |
| Induction of CXC chemokines in A549 airway epithelial cells by trypsin and staphylococcal proteases - a possible route for neutrophilic inflammation in chronic rhinosinusitis. | Clinical and experimental immunology 20060601 |
| Overexpression of hRFI inhibits 5-fluorouracil-induced apoptosis in colorectal cancer cells via activation of NF-kappaB and upregulation of BCL-2 and BCL-XL. | Oncogene 20060525 |
| Nuclear factor-kappaB activated by capacitative Ca2+ entry enhances muscarinic receptor-mediated soluble amyloid precursor protein (sAPPalpha) release in SH-SY5Y cells. | The Journal of biological chemistry 20060505 |
| Inhibition of apolipoprotein AI gene expression by tumor necrosis factor alpha: roles for MEK/ERK and JNK signaling. | Biochemistry 20060221 |
| Mechanism of thymus- and activation-regulated chemokine (TARC)/CCL17 production and its modulation by roxithromycin. | The Journal of investigative dermatology 20050901 |
| Brain microvessel endothelial cell responses to tumor necrosis factor-alpha involve a nuclear factor kappa B (NF-kappaB) signal transduction pathway. | Brain research 20050628 |
| Interferon-gamma-dependent in vitro model for the putative keratin 17 autoimmune loop in psoriasis: exploration of pharmaco- and gene-therapeutic effects. | Skin pharmacology and physiology 20050101 |
| Functional interplay between the macrophage scavenger receptor class B type I and pitavastatin (NK-104). | Circulation 20041130 |
| Inhibition of inhibitor of nuclear factor-kappaB phosphorylation increases the efficacy of paclitaxel in in vitro and in vivo ovarian cancer models. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041115 |
| C-reactive protein enhances LOX-1 expression in human aortic endothelial cells: relevance of LOX-1 to C-reactive protein-induced endothelial dysfunction. | Circulation research 20041029 |
| Growth and survival mechanisms associated with perineural invasion in prostate cancer. | Cancer research 20040901 |
| Combined histone deacetylase and NF-kappaB inhibition sensitizes non-small cell lung cancer to cell death. | Surgery 20040801 |
| The survival effect of TNF-alpha in human neutrophils is mediated via NF-kappa B-dependent IL-8 release. | European journal of immunology 20040601 |
| 15-deoxy-delta12,14-prostaglandin J2 inhibits Bay 11-7085-induced sustained extracellular signal-regulated kinase phosphorylation and apoptosis in human articular chondrocytes and synovial fibroblasts. | The Journal of biological chemistry 20040521 |
| Glucose enhances human macrophage LOX-1 expression: role for LOX-1 in glucose-induced macrophage foam cell formation. | Circulation research 20040416 |
| Caspase-8-dependent HER-2 cleavage in response to tumor necrosis factor alpha stimulation is counteracted by nuclear factor kappaB through c-FLIP-L expression. | Cancer research 20040415 |
| Nuclear factor-kappaB contributes to interleukin-4- and interferon-dependent polymeric immunoglobulin receptor expression in human intestinal epithelial cells. | Immunology 20040101 |
| Chlamydophila pneumoniae induces ICAM-1 expression in human aortic endothelial cells via protein kinase C-dependent activation of nuclear factor-kappaB. | Circulation research 20030530 |
| Effects of NF-kappa B inhibition on mesenteric ischemia-reperfusion injury. | American journal of physiology. Gastrointestinal and liver physiology 20030401 |
| Nuclear factor kappaB inhibitors induce adhesion-dependent colon cancer apoptosis: implications for metastasis. | Cancer research 20021201 |
| 16K prolactin induces NF-kappaB activation in pulmonary fibroblasts. | The Journal of endocrinology 20021201 |
| TNF-alpha protects human primary articular chondrocytes from nitric oxide-induced apoptosis via nuclear factor-kappaB. | Laboratory investigation; a journal of technical methods and pathology 20021201 |
| NF-kappaB activation is essential for angiotensin II-dependent proliferation and migration of vascular smooth muscle cells. | Journal of molecular and cellular cardiology 20021201 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Possible new role for NF-kappaB in the resolution of inflammation. | Nature medicine 20011201 |
| An IkappaBalpha inhibitor causes leukemia cell death through a p38 MAP kinase-dependent, NF-kappaB-independent mechanism. | Cancer research 20010815 |