Home Aminos Acetic acid,2-(aminooxy)-

Acetic acid,2-(aminooxy)-

CAS No.:
645-88-5
Catalog Number:
AG006TDP
Molecular Formula:
C2H5NO3
Molecular Weight:
91.0660
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
Product Description
Catalog Number:
AG006TDP
Chemical Name:
Acetic acid,2-(aminooxy)-
CAS Number:
645-88-5
Molecular Formula:
C2H5NO3
Molecular Weight:
91.0660
MDL Number:
MFCD02236609
IUPAC Name:
2-aminooxyacetic acid
InChI:
InChI=1S/C2H5NO3/c3-6-1-2(4)5/h1,3H2,(H,4,5)
InChI Key:
NQRKYASMKDDGHT-UHFFFAOYSA-N
SMILES:
NOCC(=O)O
UNII:
14I68GI3OQ
Properties
Complexity:
52.8  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
91.027g/mol
Formal Charge:
0
Heavy Atom Count:
6  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
91.066g/mol
Monoisotopic Mass:
91.027g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
72.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-3.4  
Literature
Title Journal
Hydrogen Sulfide Contributes to Retinal Neovascularization in Ischemia-Induced Retinopathy. Investigative ophthalmology & visual science 20160601
Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases. Journal of hepatology 20160401
HDAC8 and STAT3 repress BMF gene activity in colon cancer cells. Cell death & disease 20141001
Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE). British journal of pharmacology 20130601
The role of endogenous hydrogen sulfide in pathogenesis of chronotropic dysfunction in rats with cirrhosis. European journal of pharmacology 20121205
Effects of fatty acids on cardioprotection by pre-ischaemic inhibition of the malate-aspartate shuttle. Clinical and experimental pharmacology & physiology 20121001
Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal. Toxicology and applied pharmacology 20120915
Structural determinants of the β-selectivity of a bacterial aminotransferase. The Journal of biological chemistry 20120817
Oxidative coupling of indoles with ethyl 2-(disubstituted amino)acetates: an approach to achieve indolylglycine derivatives. The Journal of organic chemistry 20120817
Salicylic acid is involved in the regulation of starvation stress-induced flowering in Lemna paucicostata. Journal of plant physiology 20120701
Hydrogen sulfide modulates contractile function in rat jejunum. The Journal of surgical research 20120615
Effects of alanine aminotransferase inhibition on the intermediary metabolism in Sparus aurata through dietary amino-oxyacetate supplementation. The British journal of nutrition 20120601
Production of a highly group-specific monoclonal antibody against zearalenone and its application in an enzyme-linked immunosorbent assay. Journal of veterinary science 20120601
Decreased insulin secretion in islets from protein malnourished rats is associated with impaired glutamate dehydrogenase function: effect of leucine supplementation. Metabolism: clinical and experimental 20120501
Mechanism of action of hydrogen sulfide on cyclic AMP formation in rat retinal pigment epithelial cells. Experimental eye research 20120501
A new mitochondrial pH biosensor for quantitative assessment of pancreatic β-cell function. Biochemical and biophysical research communications 20120427
Therapeutic effect of Yokukansan on social isolation-induced aggressive behavior of zinc-deficient and pair-fed mice. Brain research bulletin 20120410
Inducible hydrogen sulfide synthesis in chondrocytes and mesenchymal progenitor cells: is H2S a novel cytoprotective mediator in the inflamed joint? Journal of cellular and molecular medicine 20120401
Two alanine aminotranferases link mitochondrial glycolate oxidation to the major photorespiratory pathway in Arabidopsis and rice. Journal of experimental botany 20120401
Malate-aspartate shuttle and exogenous NADH/cytochrome c electron transport pathway as two independent cytosolic reducing equivalent transfer systems. Archives of biochemistry and biophysics 20120215
Mode of action of cationic antimicrobial peptides defines the tethering position and the efficacy of biocidal surfaces. Bioconjugate chemistry 20120118
Hydrogen sulfide as a cryogenic mediator of hypoxia-induced anapyrexia. Neuroscience 20120110
Involvement of hydrogen peroxide, calcium, and ethylene in the induction of the alternative pathway in chilling-stressed Arabidopsis callus. Planta 20120101
Interdependency of cystathione γ-lyase and cystathione β-synthase in hydrogen sulfide-induced blood pressure regulation in rats. American journal of hypertension 20120101
Biochemical analyses are instrumental in identifying the impact of mutations on holo and/or apo-forms and on the region(s) of alanine:glyoxylate aminotransferase variants associated with primary hyperoxaluria type I. Molecular genetics and metabolism 20120101
Chlorophyll a fluorescence as a tool in evaluating the effects of ABA content and ethylene inhibitors on quality of flowering potted Bougainvillea. TheScientificWorldJournal 20120101
[11C]flumazenil binding is increased in a dose-dependent manner with tiagabine-induced elevations in GABA levels. PloS one 20120101
Inhibitory action of antidepressants on mouse Betaine/GABA transporter (BGT1) heterologously expressed in cell cultures. International journal of molecular sciences 20120101
Zimelidine attenuates the development of tolerance to morphine-induced antinociception. Indian journal of pharmacology 20120101
Anticonvulsant drugs, brain glutamate dehydrogenase activity and oxygen consumption. ISRN pharmacology 20120101
GABA metabolism and transport: effects on synaptic efficacy. Neural plasticity 20120101
Differential effects of cystathionine-γ-lyase-dependent vasodilatory H2S in periadventitial vasoregulation of rat and mouse aortas. PloS one 20120101
Glucose is a pH-dependent motor for sperm beat frequency during early activation. PloS one 20120101
Evidence that endogenous hydrogen sulfide exerts an excitatory effect on gastric motility in mice. European journal of pharmacology 20111230
Hydrogen exchange during cell-free incorporation of deuterated amino acids and an approach to its inhibition. Journal of biomolecular NMR 20111201
Endogenous hydrogen sulfide is involved in asymmetric dimethylarginine-induced protection against neurotoxicity of 1-methyl-4-phenyl-pyridinium ion. Neurochemical research 20111101
Hydrogen sulfide augments synaptic neurotransmission in the nucleus of the solitary tract. Journal of neurophysiology 20111001
Possible role of cysteine-S-conjugate β-lyase in species differences in cisplatin nephrotoxicity. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110901
GABA and Dopamine Release from Different Brain Regions in Mice with Chronic Exposure to Organophosphate Methamidophos. Journal of toxicologic pathology 20110901
Alkylated hydroxylamine derivatives eliminate peripheral retinylidene Schiff bases but cannot enter the retinal binding pocket of light-activated rhodopsin. Biochemistry 20110823
Metabolic fingerprint of ischaemic cardioprotection: importance of the malate-aspartate shuttle. Cardiovascular research 20110801
Endogenous production of hydrogen sulfide in isolated bovine eye. Neurochemical research 20110801
Polyamine-induced modulation of genes involved in ethylene biosynthesis and signalling pathways and nitric oxide production during olive mature fruit abscission. Journal of experimental botany 20110801
Modes of action of microbially-produced phytotoxins. Toxins 20110801
Plasma membrane electron transport in pancreatic β-cells is mediated in part by NQO1. American journal of physiology. Endocrinology and metabolism 20110701
Kynurenic acid synthesis and kynurenine aminotransferases expression in colon derived normal and cancer cells. Scandinavian journal of gastroenterology 20110701
A practical method for cell-free protein synthesis to avoid stable isotope scrambling and dilution. Analytical biochemistry 20110415
Impaired mitochondrial function in the preimplantation embryo perturbs fetal and placental development in the mouse. Biology of reproduction 20110301
Cadmium induced radioadaptive response via an ATM-independent H(2)S/cystathionine γ-lyase modulation. Mutation research 20110210
Efficient synthesis of an (aminooxy) acetylated-somatostatin derivative using (aminooxy)acetic acid as a 'carbonyl capture' reagent. Journal of peptide science : an official publication of the European Peptide Society 20110101
Cyanide, a coproduct of plant hormone ethylene biosynthesis, contributes to the resistance of rice to blast fungus. Plant physiology 20110101
Ethylene is involved in the regulation of iron homeostasis by regulating the expression of iron-acquisition-related genes in Oryza sativa. Journal of experimental botany 20110101
Metabolic profiling based quantitative evaluation of hepatocellular metabolism in presence of adipocyte derived extracellular matrix. PloS one 20110101
Mitochondrial inhibition during preimplantation embryogenesis shifts the transcriptional profile of fetal mouse brain. Reproduction, fertility, and development 20110101
A metabolic model of the mitochondrion and its use in modelling diseases of the tricarboxylic acid cycle. BMC systems biology 20110101
Acute Immobilization Stress Modulate GABA Release from Rat Olfactory Bulb: Involvement of Endocannabinoids-Cannabinoids and Acute Stress Modulate GABA Release. International journal of cell biology 20110101
Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth. Molecular systems biology 20110101
Hydrogen sulfide contributes to hypoxia-induced radioresistance on hepatoma cells. Journal of radiation research 20110101
Petiole hyponasty: an ethylene-driven, adaptive response to changes in the environment. AoB PLANTS 20110101
[The effect of physiologically active compounds on the production of ethylene and the activity of polygalacturonase inhibiting protein in fruits]. Prikladnaia biokhimiia i mikrobiologiia 20110101
Inhibition of the malate-aspartate shuttle by pre-ischaemic aminooxyacetate loading of the heart induces cardioprotection. Cardiovascular research 20101101
Mitochondrial metabolism revisited: a route to cardioprotection. Cardiovascular research 20101101
Involvement of ethylene and hydrogen peroxide in induction of alternative respiratory pathway in salt-treated Arabidopsis calluses. Plant & cell physiology 20101001
Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans. PLoS genetics 20100801
Targeting glutamine metabolism sensitizes melanoma cells to TRAIL-induced death. Biochemical and biophysical research communications 20100716
Salicylic acid and the flowering gene FLOWERING LOCUS T homolog are involved in poor-nutrition stress-induced flowering of Pharbitis nil. Journal of plant physiology 20100415
Abscisic acid-induced resistance against the brown spot pathogen Cochliobolus miyabeanus in rice involves MAP kinase-mediated repression of ethylene signaling. Plant physiology 20100401
VEGF up-regulation by G93A superoxide dismutase and the role of malate-aspartate shuttle inhibition. Neurobiology of disease 20100301
Amino acid transamination is crucial for ischaemic cardioprotection in normal and preconditioned isolated rat hearts--focus on L-glutamate. Experimental physiology 20100101
Cancer proliferation and therapy: the Warburg effect and quantum metabolism. Theoretical biology & medical modelling 20100101
Region-specific effects on brain metabolites of hypoxia and hyperoxia overlaid on cerebral ischemia in young and old rats: a quantitative proton magnetic resonance spectroscopy study. Journal of biomedical science 20100101
Glucose sensing in the pancreatic beta cell: a computational systems analysis. Theoretical biology & medical modelling 20100101
Increased anion channel activity is an unavoidable event in ozone-induced programmed cell death. PloS one 20100101
Arabidopsis seedlings over-accumulated indole-3-acetic acid in response to aminooxyacetic acid. Bioscience, biotechnology, and biochemistry 20100101
The mechanism of abrupt transition between theta and hyper-excitable spiking activity in medial entorhinal cortex layer II stellate cells. PloS one 20100101
Silencing of the mitochondrial NADH shuttle component aspartate-glutamate carrier AGC1/Aralar1 in INS-1E cells and rat islets. The Biochemical journal 20091210
Resolving the role of plant glutamate dehydrogenase. I. In vivo real time nuclear magnetic resonance spectroscopy experiments. Plant & cell physiology 20091001
Glutamate metabolic pathways and retinal function. Journal of neurochemistry 20091001
Accumulation of p-hydroxybenzoic acid in hairy roots of Daucus carota 2: confirming biosynthetic steps through feeding of inhibitors and precursors. Journal of plant physiology 20090901
Evidence for mitochondrial and cytoplasmic N-acetylaspartate synthesis in SH-SY5Y neuroblastoma cells. Neurochemistry international 20090901
Gender differences in methionine accumulation and metabolism in freshly isolated mouse hepatocytes: potential roles in toxicity. Toxicology and applied pharmacology 20090501
Effect of hydrogen sulfide on sympathetic neurotransmission and catecholamine levels in isolated porcine iris-ciliary body. Neurochemical research 20090301
Heterologous expression analyses of rice OsCAS in Arabidopsis and in yeast provide evidence for its roles in cyanide detoxification rather than in cysteine synthesis in vivo. Journal of experimental botany 20090301
Disruption of mitochondrial malate-aspartate shuttle activity in mouse blastocysts impairs viability and fetal growth. Biology of reproduction 20090201
Hydrogen sulfide stimulates catecholamine secretion in rainbow trout (Oncorhynchus mykiss). American journal of physiology. Regulatory, integrative and comparative physiology 20090101
N-Acetylcarnosine and histidyl-hydrazide are potent agents for multitargeted ophthalmic therapy of senile cataracts and diabetic ocular complications. Journal of drug targeting 20090101
[The effect of ethylene biosynthesis regulators on metabolic processes in the banana fruits in various physiological states]. Prikladnaia biokhimiia i mikrobiologiia 20090101
Applications of metabolomics and proteomics to the mdx mouse model of Duchenne muscular dystrophy: lessons from downstream of the transcriptome. Genome medicine 20090101
A novel function of ethylene. Gene regulation and systems biology 20090101
Extramitochondrial Ca2+ in the nanomolar range regulates glutamate-dependent oxidative phosphorylation on demand. PloS one 20090101
Mechanisms of amino acid sensing in mTOR signaling pathway. Nutrition research and practice 20090101
Neonatal monosodium glutamate administration increases aminooxyacetic acid (AOA) susceptibility effects in adult mice. Proceedings of the Western Pharmacology Society 20090101
Neo-glycopeptides: the importance of sugar core conformation in oxime-linked glycoprobes for interaction studies. Glycoconjugate journal 20081201
Inhibitory action of hydrogen sulfide on muscarinic receptor-induced contraction of isolated porcine irides. Experimental eye research 20081201
Rapid oxime and hydrazone ligations with aromatic aldehydes for biomolecular labeling. Bioconjugate chemistry 20081201
In vivo and in vitro examination of stability of primary hyperoxaluria-associated human alanine:glyoxylate aminotransferase. The Journal of biological chemistry 20081107
L-methionine-dl-sulfoxide metabolism and toxicity in freshly isolated mouse hepatocytes: gender differences and inhibition with aminooxyacetic acid. Drug metabolism and disposition: the biological fate of chemicals 20081101
Metabolomic and mass isotopomer analysis of liver gluconeogenesis and citric acid cycle. I. Interrelation between gluconeogenesis and cataplerosis; formation of methoxamates from aminooxyacetate and ketoacids. The Journal of biological chemistry 20080808
Cardioprotection by L-glutamate during postischaemic reperfusion: reduced infarct size and enhanced glycogen resynthesis in a rat insulin-free heart model. Clinical and experimental pharmacology & physiology 20080801
Phenylalanine ammonia-lyase-mediated biosynthesis of 2-hydroxy-4-methoxybenzaldehyde in roots of Hemidesmus indicus. Journal of plant physiology 20080707
An amine: hydroxyacetone aminotransferase from Moraxella lacunata WZ34 for alaninol synthesis. Bioprocess and biosystems engineering 20080601
Hydrogen sulphide in the hypothalamus causes an ATP-sensitive K+ channel-dependent decrease in blood pressure in freely moving rats. Neuroscience 20080303
1-Ethoxyethylidene, a new group for the stepwise SPPS of aminooxyacetic acid containing peptides. The Journal of organic chemistry 20080201
Properties of serine:glyoxylate aminotransferase purified from Arabidopsis thaliana leaves. Acta biochimica et biophysica Sinica 20080201
A tunable, chemoselective, and moldable biodegradable polyester for cell scaffolds. Chembiochem : a European journal of chemical biology 20080104
D-Serine dehydratase from chicken kidney: a vertebral homologue of the cryptic enzyme from Burkholderia cepacia. Journal of biochemistry 20080101
Increase in the contribution of transamination to the respiration of mitochondria during arousal. Cryo letters 20080101
An electroactive catalytic dynamic substrate that immobilizes and releases patterned ligands, proteins, and cells. Angewandte Chemie (International ed. in English) 20080101
Exogenous hydrogen sulfide produces hemodynamic effects by triggering central neuroregulatory mechanisms. Acta neurobiologiae experimentalis 20080101
Targeting aspartate aminotransferase in breast cancer. Breast cancer research : BCR 20080101
[Transamination in the mechanism of protection of mitochondria from Ca2+ overload]. Biomeditsinskaia khimiia 20080101
Ethylene is required for elicitin-induced oxidative burst but not for cell death induction in tobacco cell suspension cultures. Journal of plant physiology 20071201
S-(1,2,2-trichlorovinyl)-L-cysteine sulfoxide, a reactive metabolite of S-(1,2,2-Trichlorovinyl)-L-cysteine formed in rat liver and kidney microsomes, is a potent nephrotoxicant. The Journal of pharmacology and experimental therapeutics 20070601
GABA in regulation of communicative activity and sexual motivation of male mice with different psychoemotional status. Bulletin of experimental biology and medicine 20070201
Kynurenic acid leads, dopamine follows: a new case of volume transmission in the brain? Journal of neural transmission (Vienna, Austria : 1996) 20070101
Specificity of aminoacylase III-mediated deacetylation of mercapturic acids. Drug metabolism and disposition: the biological fate of chemicals 20070101
[Selective labeling of barstar in a T7 polymerase system by 15N-isotopes]. Biofizika 20070101
Hyperglycemia enhances the inhibitory effect of mitochondrial toxins and D,L-homocysteine on the brain production of kynurenic acid. Pharmacological reports : PR 20070101
An assessment of the role of ethylene in mediating lettuce (Lactuca sativa) root growth at high temperatures. Journal of experimental botany 20070101
Immobilization of ligands with precise control of density to electroactive surfaces. Journal of the American Chemical Society 20061206
Contribution of ethylene biosynthesis for resistance to blast fungus infection in young rice plants. Plant physiology 20061101
Cisplatin-induced toxicity is associated with platinum deposition in mouse kidney mitochondria in vivo and with selective inactivation of the alpha-ketoglutarate dehydrogenase complex in LLC-PK1 cells. Biochemistry 20060725
Nonezymatic formation of succinate in mitochondria under oxidative stress. Free radical biology & medicine 20060701
Hydrogen sulfide inhibits nitric oxide production and nuclear factor-kappaB via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide. Free radical biology & medicine 20060701
Oligosaccharide microarrays fabricated on aminooxyacetyl functionalized glass surface for characterization of carbohydrate-protein interaction. Biosensors & bioelectronics 20060215
Neuronal and astrocytic shuttle mechanisms for cytosolic-mitochondrial transfer of reducing equivalents: current evidence and pharmacological tools. Biochemical pharmacology 20060214
High plasma cyst(e)ine level may indicate poor clinical outcome in patients with acute stroke: possible involvement of hydrogen sulfide. Journal of neuropathology and experimental neurology 20060201
Enzymatic and mechanistic studies on the formation of N-phenylglycolohydroxamic acid from nitrosobenzene and pyruvate in spinach leaf homogenate. Journal of agricultural and food chemistry 20060125
Demonstration of extensive GABA synthesis in the small population of GAD positive neurons in cerebellar cultures by the use of pharmacological tools. Neurochemistry international 20060101
Multibranch and pseudopeptide approach for design of novel inhibitors of subtilisin kexin isozyme-1. Protein and peptide letters 20060101
Transamination in the metabolism of the nephrotoxicant N-(3,5-dichlorophenyl)succinimide in rats. Drug metabolism and disposition: the biological fate of chemicals 20051201
Effect of aminooxyacetic acid on extracellular level of D-serine in rat striatum: an in vivo microdialysis study. European journal of pharmacology 20051121
Cultures of rat astrocytes challenged with a steady supply of glutamate: new model to study flux distribution in the glutamate-glutamine cycle. Glia 20050901
Alpha-Ketoisocaproate-induced hypersecretion of insulin by islets from diabetes-susceptible mice. American journal of physiology. Endocrinology and metabolism 20050801
Demonstration of kynurenine aminotransferases I and II and characterization of kynurenic acid synthesis in oligodendrocyte cell line (OLN-93). Neurochemical research 20050801
Gamma-aminobutyric acid and mefloquine-induced seizures in mice. Progress in neuro-psychopharmacology & biological psychiatry 20050701
Demonstration of kynurenine aminotransferases I and II and characterization of kynurenic acid synthesis in cultured cerebral cortical neurons. Journal of neuroscience research 20050601
Differential expression of genes encoding 1-aminocyclopropane-1-carboxylate synthase in Arabidopsis during hypoxia. Plant molecular biology 20050501
Structure of P-protein of the glycine cleavage system: implications for nonketotic hyperglycinemia. The EMBO journal 20050420
Automorphosis of etiolated pea seedlings in space is simulated by a three-dimensional clinostat and the application of inhibitors of auxin polar transport. Physiologia plantarum 20050401
Chronic exposure to beta-hydroxybutyrate inhibits glucose-induced insulin release from pancreatic islets by decreasing NADH contents. American journal of physiology. Endocrinology and metabolism 20050201
Enhancement of photorespiration in immobilized Chlamydomonas reinhardtii cells. Biotechnology letters 20050201
Nitrogen-15 NMR studies of nitrogen metabolism in Picea glauca buds. Plant physiology and biochemistry : PPB 20041201
Isolation and characterization of cytosolic alanine aminotransferase isoforms from starved rat liver. Molecular and cellular biochemistry 20041201
Aminooxyacetic acid inhibits antheridiogenesis and development of Anemia phyllitidis gametophytes. Plant cell reports 20041001
Crystal structures of unbound and aminooxyacetate-bound Escherichia coli gamma-aminobutyrate aminotransferase. Biochemistry 20040831
Androgen secretion by Rcho-1 cells is independent of extracellular glutamate concentration. Placenta 20040701
Inhibition of [(15)N]valine transamination during selective labeling of barstar in a T7 polymerase system. Biochemistry. Biokhimiia 20040701
Differential in vitro development of inflorescences in long and short day Lemna spp.: involvement of ethylene and polyamines. Journal of plant physiology 20040601
Energy substrate requirements of rat retinal pigmented epithelial cells in culture: relative importance of glucose, amino acids, and monocarboxylates. Investigative ophthalmology & visual science 20040401
Kynurenic acid production in cultured bovine aortic endothelial cells. Homocysteine is a potent inhibitor. Naunyn-Schmiedeberg's archives of pharmacology 20040301
Cellular glutathione prevents cytolethality of monomethylarsonic acid. Toxicology and applied pharmacology 20040301
A proteomic analysis identifies glutathione S-transferase isoforms whose abundance is differentially regulated by ethylene during the formation of early root epidermis in Arabidopsis seedlings. Biochimica et biophysica acta 20040220
Enhanced survival effect of pyruvate correlates MAPK and NF-kappaB activation in hydrogen peroxide-treated human endothelial cells. Journal of applied physiology (Bethesda, Md. : 1985) 20040201
Retinal function loss after monocarboxylate transport inhibition. Investigative ophthalmology & visual science 20040201
Purification and properties of cytosolic alanine aminotransferase from the liver of two freshwater fish, Clarias batrachus and Labeo rohita. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20040201
Reactive oxygen and ethylene are involved in the regulation of regurgitant-induced responses in bean plants. Journal of plant physiology 20040201
Opioid modulation of GABA release in the rat inferior colliculus. BMC neuroscience 20040101
Branched-chain amino acid aminotransferase and methionine formation in Mycobacterium tuberculosis. BMC microbiology 20040101
Distinct trans-plasma membrane redox pathways reduce cell-impermeable dyes in HeLa cells. Redox report : communications in free radical research 20040101
13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and gamma-glutamyl cycle activity in a clonal pancreatic beta-cell line. Diabetologia 20031101
Does ethylene mediate cluster root formation under iron deficiency? Annals of botany 20031101
Overproduced ethylene causes programmed cell death leading to temperature-sensitive lethality in hybrid seedlings from the cross Nicotiana suaveolens x N. tabacum. Planta 20030901
Mechanisms of pyruvate inhibition of oxidant-induced apoptosis in human endothelial cells. Microvascular research 20030901
Modulation of endogenous production of H2S in rat tissues. Canadian journal of physiology and pharmacology 20030901
Renal cysteine conjugate C-S lyase mediated toxicity of halogenated alkenes in primary cultures of human and rat proximal tubular cells. Archives of toxicology 20030701
Distinguishing features of leucine and alpha-ketoisocaproate sensing in pancreatic beta-cells. Endocrinology 20030501
Ethylene insensitivity modulates ozone-induced cell death in birch. Plant physiology 20030501
The metabolic pathway of salicylic acid rather than of chlorogenic acid is involved in the stress-induced flowering of Pharbitis nil. Journal of plant physiology 20030501
Demonstration of functional coupling between gamma -aminobutyric acid (GABA) synthesis and vesicular GABA transport into synaptic vesicles. Proceedings of the National Academy of Sciences of the United States of America 20030401
A MAPK pathway mediates ethylene signaling in plants. The EMBO journal 20030317
Glutamine deprivation facilitates tumour necrosis factor induced bacterial translocation in Caco-2 cells by depletion of enterocyte fuel substrate. Gut 20030201
Metabolism of Cisplatin to a nephrotoxin in proximal tubule cells. Journal of the American Society of Nephrology : JASN 20030101
Kynurenate production by cultured human astrocytes. Journal of neural transmission (Vienna, Austria : 1996) 20030101
Role of mitochondrial NADH shuttle system in acute amylase secretion by acetylcholine from mouse pancreatic acinar cells. The Tohoku journal of experimental medicine 20021101
Sulfoxides as urinary metabolites of S-allyl-L-cysteine in rats: evidence for the involvement of flavin-containing monooxygenases. Drug metabolism and disposition: the biological fate of chemicals 20021001
Site-specific incorporation of (aminooxy)acetic acid into proteins. Biochemistry 20020924
Enzymatic hydrogen sulfide production in marine invertebrate tissues. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20020901
The smooth muscle relaxant effect of hydrogen sulphide in vitro: evidence for a physiological role to control intestinal contractility. British journal of pharmacology 20020901
Pancreatic islet beta-cells transiently metabolize pyruvate. The Journal of biological chemistry 20020823
Regulation of amino acid uptake in conifers by exogenous and endogenous nitrogen. Planta 20020801
Endothelium-dependent production and liberation of kynurenic acid by rat aortic rings exposed to L-kynurenine. European journal of pharmacology 20020719
The effects of haloalkene cysteine conjugates on cytosolic free calcium levels in LLC-PK(1) cells--studies utilising digital imaging fluorescence microscopy. Toxicology 20020614
Aspartate aminotransferase isotope exchange reactions: implications for glutamate/glutamine shuttle hypothesis. American journal of physiology. Cell physiology 20020601
Beta-lyase-dependent attenuation of cisplatin-mediated toxicity by selenocysteine Se-conjugates in renal tubular cell lines. The Journal of pharmacology and experimental therapeutics 20020601
Inhibition of bacterial pyridoxal-depending enzymes by (aminooxy)-acetic acid improves selective 15N isotope labeling of bacterially expressed protein. BioTechniques 20020601
Memory impairment in temporal lobe epilepsy: the role of entorhinal lesions. Epilepsy research 20020601
Posttranslational alanine trans-stimulation of zwitterionic amino acid transport systems in human intestinal Caco-2 cells. The Journal of surgical research 20020501
A major human arsenic metabolite, dimethylarsinic acid, requires reduced glutathione to induce apoptosis. Chemical research in toxicology 20020501
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
Mechanisms of the protective effect of L-alanine to D-galactosamine-induced hepatocellular injury: comparative studies of L-alanine and pyruvate. Biochemical and biophysical research communications 20020308
Ontogenic modifications in the effect of the GABAergic system on the hypothalamic excitatory amino acids: its relationship with GABAergic control of gonadotrophin secretion during sexual maturation in female rats. Brain research. Developmental brain research 20020131
Inhibition of gamma-glutamyl transpeptidase or cysteine S-conjugate beta-lyase activity blocks the nephrotoxicity of cisplatin in mice. The Journal of pharmacology and experimental therapeutics 20020101
Total chemical synthesis of a 27 kDa TASP protein derived from the MscL ion channel of M. tuberculosis by ketoxime-forming ligation. Bioconjugate chemistry 20020101
Concentration- and time-dependent effect of aminooxyacetic acid on cortical epileptogenicity. Acta biologica Hungarica 20020101
Alterations in Taxol production in plant cell culture via manipulation of the phenylalanine ammonia lyase pathway. Biotechnology progress 20020101
Role of specific aminotransferases in de novo glutamate synthesis and redox shuttling in the retina. Journal of neuroscience research 20011201
Ovariectomy aggravates convulsions and hippocampal gamma-aminobutyric acid inhibition induced by cyclosporin A in rats. European journal of pharmacology 20011102
Disruption of inhibition in area CA1 of the hippocampus in a rat model of temporal lobe epilepsy. Journal of neurophysiology 20011101
Seizures induced by intracerebral administration of pyridoxal-5'-phosphate: effect of GABAergic drugs and glutamate receptor antagonists. Neuropharmacology 20011001
IAA and N(6)-benzyladenine inhibit ethylene-regulated expression of ACC oxidase and ACC synthase genes in mungbean hypocotyls. Plant & cell physiology 20011001
TCA cycle kinetics in the rat heart by analysis of (13)C isotopomers using indirect (1)H. American journal of physiology. Heart and circulatory physiology 20010901
Effect of alkylpyrazine derivatives on the duration of pentobarbital-induced sleep, picrotoxicin-induced convulsion and gamma-aminobutyric acid (GABA) levels in the mouse brain. Biological & pharmaceutical bulletin 20010901
Possible involvement of auxin-induced ethylene in an apoptotic cell death during temperature-sensitive lethality expressed by hybrid between Nicotiana glutinosa and N. repanda. Plant & cell physiology 20010901
Real-time [11C]methionine translocation in barley in relation to mugineic acid phytosiderophore biosynthesis. Planta 20010901
Bioactivation of chemopreventive selenocysteine Se-conjugates and related amino acids by amino acid oxidases novel route of metabolism of selenoamino acids. Chemical research in toxicology 20010801
Metabolic and functional studies on isolated islets in a new rat model of type 2 diabetes. Molecular and cellular endocrinology 20010425
Involvement of ethylene in the maturation of black spruce embryogenic cell lines with different maturation capacities. Journal of experimental botany 20010401
Glutamate regulates the viability of retinal cells in culture. Vision research 20010301
Lactation alters gamma-aminobutyric acid neuronal activity in the hypothalamus and cerebral cortex in the rat. Neuroendocrinology 20010301
Role of mitochondrial dysfunction in S-(1,2-dichlorovinyl)-l-cysteine-induced apoptosis. Toxicology and applied pharmacology 20010201
Cysteine conjugate of methazolamide is metabolized by beta-lyase. Journal of pharmaceutical sciences 20010201
Polyhydroxybenzoates inhibit ascorbic acid activation of mitochondrial glycerol-3-phosphate dehydrogenase: implications for glucose metabolism and insulin secretion. The Journal of biological chemistry 20010126
Contribution of glutamate dehydrogenase to mitochondrial glutamate metabolism studied by (13)C and (31)P nuclear magnetic resonance. Journal of experimental botany 20010101
Evidence for intraocular synthesis of kynurenic acid, a putative endogenous neuroprotectant. Ophthalmic research 20010101
Asparagine uptake in rat hepatocytes: resolution of a paradox and insights into substrate-dependent transporter regulation. Amino acids 20010101
NADH shuttle system regulates K(ATP) channel-dependent pathway and steps distal to cytosolic Ca(2+) concentration elevation in glucose-induced insulin secretion. The Journal of biological chemistry 19990903
[Role of the NADH shuttle system in glucose-induced insulin secretion]. Nihon rinsho. Japanese journal of clinical medicine 19990301
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice. General pharmacology 19990301
Role of the renal cysteine conjugate beta-lyase pathway in inhaled compound A nephrotoxicity in rats. Anesthesiology 19980601
The nephrotoxicity and hepatotoxicity of 1,1,2,2-tetrafluoroethyl-L-cysteine in the rat. Archives of toxicology 19980501
Quantitative differences in the production and toxicity of CF2=BrCl versus CH2F-O-C(=CF2)(CF3) (compound A): the safety of halothane does not indicate the safety of sevoflurane. Anesthesia and analgesia 19971101
Neurotoxic convulsions induced by histamine H2 receptor antagonists in mice. Toxicology and applied pharmacology 19960201
NG-nitro-L-arginine, a nitric oxide synthase inhibitor, and seizure susceptibility in four seizure models in mice. Journal of neural transmission (Vienna, Austria : 1996) 19960101
GABAergic and dopaminergic systems may be involved in seizures induced by pyrimethamine in mice. General pharmacology 19941001
Aminooxyacetic acid striatal lesions attenuated by 1,3-butanediol and coenzyme Q10. Neuroscience letters 19940815
Nephrotoxicity of 4-amino-3-S-glutathionylphenol and its modulation by metabolism or transport inhibitors. Archives of toxicology 19940101
Aminooxyacetic acid-induced accumulation of GABA enhances clonidine hypotension. Polish journal of pharmacology 19940101
Cimetidine-induced seizures in mice. Antagonism by some GABAergic agents. Biochemical pharmacology 19931214
Effects of some GABAergic agents on quinine-induced seizures in mice. Experientia 19920715
Age dependency of the susceptibility of rats to aminooxyacetic acid seizures. Brain research. Developmental brain research 19920619
Involvement of GABAergic mechanisms in chloroquine-induced seizures in mice. General pharmacology 19920301
Some correlations between local anesthetic-induced convulsions and gamma-aminobutyric acid in rat spinal cord. Japanese journal of pharmacology 19910701
In vivo nephrotoxic action of an isomeric mixture of S-(1-phenyl-2-hydroxyethyl)glutathione and S-(2-phenyl-2-hydroxyethyl)glutathione in Fischer-344 rats. Toxicology 19910325
Genotoxicity of ochratoxin A and structurally related compounds in Escherichia coli strains: studies on their mode of action. IARC scientific publications 19910101
The effect of haloalkene cysteine conjugates on rat renal glutathione reductase and lipoyl dehydrogenase activities. Toxicology and applied pharmacology 19900601
A functional interaction between GABA and 5-HT in inhibiting picrotoxin-induced myoclonus in rats. Indian journal of physiology and pharmacology 19900401
The synergistic protective effect of propranolol & aminooxyacetic acid against picrotoxin-induced myoclonus in rats. The Indian journal of medical research 19900201
The antimyoclonic action of clonazepam through a GABA--independent mechanism. Indian journal of physiology and pharmacology 19890101
[Experimental study of the antiepileptic activity of fenibut and its combinations with sodium valproate and aminooxyacetic acid]. Farmakologiia i toksikologiia 19880101
Deacetylation and further metabolism of the mercapturic acid of hexachloro-1,3-butadiene by rat kidney cytosol in vitro. Archives of toxicology 19880101
Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity. Biochemical pharmacology 19860115
The influence of gabaergic system on cataleptogenic action of analgesics and haloperidol. Polish journal of pharmacology and pharmacy 19860101
Effects of inhibitors of GABA-transaminase on hole-board exploration and on temperature. Relation with effects on quasi-morphine abstinence behaviour induced by sodium dipropylacetate. Biochemical pharmacology 19851101
Aminooxyacetic acid induced accumulation of GABA in the rat brain. Interaction with GABA receptors and distribution in compartments. Naunyn-Schmiedeberg's archives of pharmacology 19830401
Some functional changes in experimentally induced cardiac overload. Acta physiologica et pharmacologica Bulgarica 19830101
Catalepsy produced by long-acting neuroleptics, fluphenazine enanthate and fluphenazine decanoate, in mice. Pharmacology 19820101
Blockade of methamphetamine-induced depression of tyrosine hydroxylase by GABA transaminase inhibitors. European journal of pharmacology 19800829
Effect of GABA analogues on blood pressure and central GABA metabolism in the rat. Acta pharmacologica et toxicologica 19800801
The effect of baclofen and aminooxyacetic acid on the action of drugs stimulating the dopaminergic system. Polish journal of pharmacology and pharmacy 19780101
Arginine decarboxylase from a Pseudomonas species. Journal of bacteriology 19760201
Kinetics of alpha-chymotrypsin dimerization. The Journal of biological chemistry 19760125
Effects of aminooxyacetic acid and baclofen on catalepsy, striatal homovanillic acid increase and antinociception caused by methadone in rats. Acta pharmacologica et toxicologica 19760101
Inhibition by apomorphine of the metoclopramide-induced catalepsy and increase in striatal homovanillic acid content. British journal of pharmacology 19751101
Properties