N-(2-(2,4,6-Trichlorophenoxy)ethyl)propan-1-amine
Title | Journal |
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Association of KCNJ11 E23K gene polymorphism with hypoglycemia in sulfonylurea-treated type 2 diabetic patients. | Diabetes research and clinical practice 20121001 |
Gene networks modified by sulphonylureas in beta cells: a pathway-based analysis of insulin secretion and cell death. | Basic & clinical pharmacology & toxicology 20121001 |
Blockers of sulfonylureas receptor 1 subunits may lead to cardiac protection against isoprenaline-induced injury in obese rats. | European journal of pharmacology 20120905 |
Development of novel gastroretentive floating particulate drug delivery system of gliclazide. | Current drug delivery 20120901 |
Protective effect of gliclazide on diabetic peripheral neuropathy through Drp-1 mediated-oxidative stress and apoptosis. | Neuroscience letters 20120808 |
Probiotics decreased the bioavailability of the bile acid analog, monoketocholic acid, when coadministered with gliclazide, in healthy but not diabetic rats. | European journal of drug metabolism and pharmacokinetics 20120601 |
Physicochemical investigations and stability studies of amorphous gliclazide. | AAPS PharmSciTech 20120601 |
Gliclazide may have an antiapoptotic effect related to its antioxidant properties in human normal and cancer cells. | Molecular biology reports 20120501 |
Novel tamarind seed polysaccharide-alginate mucoadhesive microspheres for oral gliclazide delivery: in vitro-in vivo evaluation. | Drug delivery 20120401 |
KCNJ11 gene E23K variant and therapeutic response to sulfonylureas. | European journal of internal medicine 20120401 |
Protective effects of combined therapy of gliclazide with curcumin in experimental diabetic neuropathy in rats. | Behavioural pharmacology 20120401 |
Pharmacogenomic analysis of ATP-sensitive potassium channels coexpressing the common type 2 diabetes risk variants E23K and S1369A. | Pharmacogenetics and genomics 20120301 |
Variations in tissue selectivity amongst insulin secretagogues: a systematic review. | Diabetes, obesity & metabolism 20120201 |
Glycaemic control and cost analysis when changing from gliclazide co-administered with metformin to pre-combined glibenclamide-metformin tablets in type 2 diabetes mellitus. | The Medical journal of Malaysia 20120201 |
Effects of pioglitazone add-on to gliclazide and metformin on glycemic control in patients with type 2 diabetes. | Endocrine research 20120101 |
Treating diabetes today with gliclazide MR: a matter of numbers. | Diabetes, obesity & metabolism 20120101 |
Protective effects of beta glucan and gliclazide on brain tissue and sciatic nerve of diabetic rats induced by streptozosin. | Experimental diabetes research 20120101 |
Gliclazide does not fully prevent 2-deoxy-D-ribose-induced oxidative damage because it does not restore glutathione content in a pancreatic β-cell line. | Oxidative medicine and cellular longevity 20120101 |
Antidiabetic effect of S-allylcysteine: effect on thyroid hormone and circulatory antioxidant system in experimental diabetic rats. | Journal of diabetes and its complications 20120101 |
[Diabetes mellitus and chronic kideny disease: modern diagnostics and treatment]. | Vestnik Rossiiskoi akademii meditsinskikh nauk 20120101 |
Does glycemic control offer similar benefits among patients with diabetes in different regions of the world? Results from the ADVANCE trial. | Diabetes care 20111201 |
Development, optimization, and anti-diabetic activity of gliclazide-loaded alginate-methyl cellulose mucoadhesive microcapsules. | AAPS PharmSciTech 20111201 |
[Incretin-based therapy for treating patients with type 2 diabetes]. | Orvosi hetilap 20111127 |
High-performance affinity chromatography and the analysis of drug interactions with modified proteins: binding of gliclazide with glycated human serum albumin. | Analytical and bioanalytical chemistry 20111101 |
[Hypoglycemia]. | Praxis 20111019 |
Effect of binary and ternary solid dispersions on the in vitro dissolution and in-situ rabbit intestinal absorption of gliclazide. | Pakistan journal of pharmaceutical sciences 20111001 |
Dissolution rate enhancement of gliclazide by ordered mixing. | Acta pharmaceutica (Zagreb, Croatia) 20110901 |
Antidiabetic and antioxidant potentials of Euphorbia hirta leaves extract studied in streptozotocin-induced experimental diabetes in rats. | General physiology and biophysics 20110901 |
AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study. | Diabetologia 20110701 |
Intensive glucose control and risk of cancer in patients with type 2 diabetes. | Diabetologia 20110701 |
Comparison of the dipeptidyl peptidase-4 inhibitor vildagliptin and the sulphonylurea gliclazide in combination with metformin, in Muslim patients with type 2 diabetes mellitus fasting during Ramadan: results of the VECTOR study. | Current medical research and opinion 20110701 |
Formulation and evaluation of Ficus glomerata mucilage sustained release matrix tablets of gliclazide. | Pakistan journal of pharmaceutical sciences 20110701 |
Pharmacokinetic-pharmacodynamic equivalence of three gliclazide formulations in healthy human male subjects. | International journal of clinical pharmacology and therapeutics 20110701 |
Reduced catalytic activity of human CYP2C9 natural alleles for gliclazide: molecular dynamics simulation and docking studies. | Biochimie 20110601 |
Effects of gliclazide on endothelial function in patients with newly diagnosed type 2 diabetes. | European journal of pharmacology 20110601 |
Diagnosis in diabetes: does it matter? | The journal of the Royal College of Physicians of Edinburgh 20110601 |
Molecular dynamics simulation of drug uptake by polymer. | Journal of molecular modeling 20110501 |
In vitro-in vivo correlation for gliclazide immediate-release tablets based on mechanistic absorption simulation. | AAPS PharmSciTech 20110301 |
Insulin and metformin may prevent renal injury in young type 2 diabetic Goto-Kakizaki rats. | European journal of pharmacology 20110225 |
Comparison of two sulfonylureas with high and low myocardial K(ATP) channel affinity on myocardial infarct size and metabolism in a rat model of type 2 diabetes. | Diabetologia 20110201 |
Design and development of gliclazide-loaded chitosan microparticles for oral sustained drug delivery: in-vitro/in-vivo evaluation. | The Journal of pharmacy and pharmacology 20110201 |
Design and development of gliclazide-loaded chitosan for oral sustained drug delivery: in vitro/in vivo evaluation. | Journal of microencapsulation 20110101 |
Response to oral gliclazide in a pre-pubertal child with hepatic nuclear factor-1 alpha maturity onset diabetes of the young. | Annals of Saudi medicine 20110101 |
Effect of repaglinide and gliclazide on glycaemic control, early-phase insulin secretion and lipid profiles in. | Chinese medical journal 20110101 |
Ramsay Hunt syndrome with unilateral polyneuropathy involving cranial nerves V, VII, VIII, and XII in a diabetic patient. | Quintessence international (Berlin, Germany : 1985) 20110101 |
[Comparative characteristics of antioxidant properties of hypoglycemic agents diabenol and gliclazide]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
Design and evaluation of a novel formulation prediction system. | International journal of pharmaceutics 20101215 |
Antidiabetic effect of S-allylcysteine: Effect on plasma and tissue glycoproteins in experimental diabetes. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20101201 |
Beneficial effect of S-allylcysteine (SAC) on blood glucose and pancreatic antioxidant system in streptozotocin diabetic rats. | Plant foods for human nutrition (Dordrecht, Netherlands) 20101201 |
Hydrochloride pioglitazone decreases urinary cytokines excretion in type 2 diabetes. | Clinical endocrinology 20101201 |
Use of sulphonylurea and cancer in type 2 diabetes-The Hong Kong Diabetes Registry. | Diabetes research and clinical practice 20101201 |
Erectile dysfunction and later cardiovascular disease in men with type 2 diabetes: prospective cohort study based on the ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation) trial. | Journal of the American College of Cardiology 20101130 |
Severe hypoglycemia and risks of vascular events and death. | The New England journal of medicine 20101007 |
Effects of metformin plus gliclazide compared with metformin alone on circulating endothelial progenitor cell in type 2 diabetic patients. | Endocrine 20101001 |
Effects of gliclazide on platelet aggregation and the plasminogen activator inhibitor type 1 level in patients with type 2 diabetes mellitus. | Metabolism: clinical and experimental 20100901 |
Physicochemical characterization of gliclazide-macrogol solid dispersion and tablets based on optimized dispersion. | Drug development and industrial pharmacy 20100801 |
The efficacy of lowering glycated haemoglobin with a gliclazide modified release-based intensive glucose lowering regimen in the ADVANCE trial. | Diabetes research and clinical practice 20100801 |
Resveratrol attenuates hyperglycemia-mediated oxidative stress, proinflammatory cytokines and protects hepatocytes ultrastructure in streptozotocin-nicotinamide-induced experimental diabetic rats. | Chemico-biological interactions 20100730 |
Preparation and in vitro evaluation of gliclazide sustained-release matrix pellets: formulation and storage stability. | Drug development and industrial pharmacy 20100701 |
Maintenance of glycaemic control with the evening administration of a long acting sulphonylurea in male type 2 diabetic patients undertaking the Ramadan fast. | International journal of clinical practice 20100701 |
Gliclazide microcrystals prepared by two methods of in situ micronization: pharmacokinetic studies in diabetic and normal rats. | AAPS PharmSciTech 20100601 |
Effect of gliclazide on nucleotide excision repair (NER) and non-homologous DNA end joining (NHEJ) in normal and cancer cells. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100601 |
Influence of CYP2C9 and CYP2C19 genetic polymorphisms on pharmacokinetics and pharmacodynamics of gliclazide in healthy Chinese Han volunteers. | Journal of clinical pharmacy and therapeutics 20100601 |
Three novel mutations in MODY and its phenotype in three different Czech families. | Diabetes research and clinical practice 20100501 |
Effects of short-term therapy with different insulin secretagogues on glucose metabolism, lipid parameters and oxidative stress in newly diagnosed Type 2 Diabetes Mellitus. | Diabetes research and clinical practice 20100401 |
Comparison of ultraviolet detection, evaporative light scattering detection and charged aerosol detection methods for liquid-chromatographic determination of anti-diabetic drugs. | Journal of pharmaceutical and biomedical analysis 20100311 |
Comparison of insulin sensitivity, glucose sensitivity, and first phase insulin secretion in patients treated with repaglinide or gliclazide. | Archives of pharmacal research 20100301 |
Comparison of metformin, gliclazide MR and rosiglitazone in monotherapy and in combination for type 2 diabetes. | Arquivos brasileiros de endocrinologia e metabologia 20100301 |
A comparison of efficacy and safety of vildagliptin and gliclazide in combination with metformin in patients with Type 2 diabetes inadequately controlled with metformin alone: a 52-week, randomized study. | Diabetic medicine : a journal of the British Diabetic Association 20100301 |
Evaluation of different tests based on observations for external model evaluation of population analyses. | Journal of pharmacokinetics and pharmacodynamics 20100201 |
Evaluation of efficacy and tolerability of gliclazide and metformin combination: a multicentric study in patients with type 2 diabetes mellitus uncontrolled on monotherapy with sulfonylurea or metformin. | American journal of therapeutics 20100101 |
Present status of sulfonylurea treatment for type 2 diabetes in Japan: second report of a cross-sectional survey of 15,652 patients. | Endocrine journal 20100101 |
[Dynamics of structural-functional parameters of cardiovascular system during use of complex therapy of women with type 2 diabetes mellitus]. | Kardiologiia 20100101 |
[Capabilities of hypoglycemic therapy in women with decompensated type 2 diabetes mellitus]. | Terapevticheskii arkhiv 20100101 |
Sulphonylureas and cancer: a case-control study. | Acta diabetologica 20091201 |
Efficacy and safety comparison between the DPP-4 inhibitor vildagliptin and the sulfonylurea gliclazide after two years of monotherapy in drug-naïve patients with type 2 diabetes. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20091201 |
Glibenclamide-related excess in total and cardiovascular mortality risks: data from large Ukrainian observational cohort study. | Diabetes research and clinical practice 20091201 |
Pharmacokinetics and bioequivalence evaluation of gliclazide/metformin combination tablet and equivalent doses of gliclazide and metformin in healthy Korean subjects. | International journal of clinical pharmacology and therapeutics 20091201 |
Recent cardiovascular trials: what are the drivers of benefit and adverse effect? | Journal of diabetes 20091201 |
Suppression of KATP channel activity protects murine pancreatic beta cells against oxidative stress. | The Journal of clinical investigation 20091102 |
Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial. | Diabetes care 20091101 |
Cognitive function and risks of cardiovascular disease and hypoglycaemia in patients with type 2 diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial. | Diabetologia 20091101 |
Is there evidence that oral hypoglycemic agents reduce cardiovascular morbidity or mortality? No. | Diabetes care 20091101 |
Severe neuroglycopaenia secondary to severe hypoglycaemia from serendipitous overdose of gliclazide without adrenergic or autonomic response. | Diabetic medicine : a journal of the British Diabetic Association 20091101 |
Effect of gliclazide immobilization into layered double hydroxide on drug release. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20091001 |
Vildagliptin therapy and hypoglycaemia in Muslim type 2 diabetes patients during Ramadan. | International journal of clinical practice 20091001 |
Trace analysis of glyclazide in human plasma at microscale level by mass spectrometry. | Journal of separation science 20091001 |
Second-generation sulfonylureas preserve inhibition of mitochondrial permeability transition by the mitochondrial K+(ATP) opener nicorandil in experimental myocardial infarction. | Shock (Augusta, Ga.) 20090901 |
Effects of exposure of human islet beta-cells to normal and high glucose levels with or without gliclazide or glibenclamide. | Diabetes & metabolism 20090901 |
D-pinitol attenuates the impaired activities of hepatic key enzymes in carbohydrate metabolism of streptozotocin-induced diabetic rats. | General physiology and biophysics 20090901 |
Pioglitazone-induced acute rhabdomyolysis. | Diabetes care 20090701 |
The behavior of Gliclazide in solution and in the solid state: a case of organic compound presenting a solid-solution structure. | Magnetic resonance in chemistry : MRC 20090601 |
Physicochemical properties of solid dispersions of gliclazide in polyvinylpyrrolidone K90. | AAPS PharmSciTech 20090601 |
Modulatory effects of resveratrol on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats. | Chemico-biological interactions 20090515 |
The oral anti-diabetic agent, gliclazide, inhibits oxidized LDL-mediated LOX-1 expression, metalloproteinase-9 secretion and apoptosis in human aortic endothelial cells. | Atherosclerosis 20090501 |
Blood pressure and glucose control in subjects with diabetes: new analyses from ADVANCE. | Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20090501 |
In vive effects of gliclazide and metformin on the plasma concentration of caffeine in healthy rats. | Pakistan journal of biological sciences : PJBS 20090501 |
Overcome side identification in PPOP by making orifices on both layers. | International journal of pharmaceutics 20090417 |
Free fatty acid kinetics during long-term treatment with pioglitazone added to sulfonylurea or metformin in Type 2 diabetes. | Journal of internal medicine 20090401 |
Applying the Taguchi design for optimized formulation of sustained release gliclazide chitosan beads: an in vitro/in vivo study. | AAPS PharmSciTech 20090301 |
Antidiabetic effects of dipeptidyl peptidase-IV inhibitors and sulfonylureas in streptozotocin-nicotinamide-induced mildly diabetic mice. | Metabolism: clinical and experimental 20090301 |
Preparation and characterization of gliclazide-polyethylene glycol 4000 solid dispersions. | Acta pharmaceutica (Zagreb, Croatia) 20090301 |
The metabolism of CYP2C9 and CYP2C19 for gliclazide by homology modeling and docking study. | European journal of medicinal chemistry 20090201 |
Unexplained severe hypoglycaemia in hospital: a difficult diagnostic challenge. | British journal of clinical pharmacology 20090201 |
Treatment of HNF1-alpha MODY with the DPP-4 inhibitor Sitagliptin(1). | Diabetic medicine : a journal of the British Diabetic Association 20090201 |
Antioxidant and vascular effects of gliclazide in type 2 diabetic rats fed high-fat diet. | Physiological research 20090101 |
Normal insulin response to short-term intense exercise is abolished in Type 2 diabetic patients treated with gliclazide. | Journal of diabetes and its complications 20090101 |
Normal pregnancy and healthy child after continued exposure to gliclazide and ramipril during pregnancy. | The Annals of pharmacotherapy 20090101 |
Gliclazide reduces MKC intestinal transport in healthy but not diabetic rats. | European journal of drug metabolism and pharmacokinetics 20090101 |
Dissolution enhancement of gliclazide using pH change approach in presence of twelve stabilizers with various physico-chemical properties. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20090101 |
The efficacy of self-monitoring of blood glucose in the management of patients with type 2 diabetes treated with a gliclazide modified release-based regimen. A multicentre, randomized, parallel-group, 6-month evaluation (DINAMIC 1 study). | Diabetes, obesity & metabolism 20081201 |
Hyperglycaemia secondary to mirtazapine therapy in a 37-year-old man. | The Australian and New Zealand journal of psychiatry 20081101 |
Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients. | Diabetes care 20081001 |
Comparison of gliclazide with insulin as initial treatment modality in newly diagnosed type 2 diabetes. | Diabetes technology & therapeutics 20081001 |
optimization of extended zero-order release gliclazide tablets using D-optimal mixture design. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20081001 |
Reversible binding of antidiabetic drugs, repaglinide and gliclazide, with human serum albumin. | Chemical biology & drug design 20081001 |
Daily blood glucose profiles of glibenclamide and gliclazide taken once or twice daily in elderly type 2 diabetic patients. | Geriatrics & gerontology international 20080901 |
Differential effect of sulfonylureas on production of reactive oxygen species and apoptosis in cultured pancreatic beta-cell line, MIN6. | Metabolism: clinical and experimental 20080801 |
Is Ramadan fasting safe in type 2 diabetic patients in view of the lack of significant effect of fasting on clinical and biochemical parameters, blood pressure, and glycemic control? | Clinical and experimental hypertension (New York, N.Y. : 1993) 20080701 |
In vitro effect of gliclazide on DNA damage and repair in patients with type 2 diabetes mellitus (T2DM). | Chemico-biological interactions 20080617 |
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. | The New England journal of medicine 20080612 |
Enhancement of dissolution rate of gliclazide using solid dispersions with polyethylene glycol 6000. | AAPS PharmSciTech 20080601 |
Rosiglitazone produces a greater reduction in circulating platelet activity compared with gliclazide in patients with type 2 diabetes mellitus--an effect probably mediated by direct platelet PPARgamma activation. | Atherosclerosis 20080401 |
Effects of St John's wort and CYP2C9 genotype on the pharmacokinetics and pharmacodynamics of gliclazide. | British journal of pharmacology 20080401 |
Erythromelalgia in a diabetic patient managed with gabapentin. | Diabetes research and clinical practice 20080301 |
Therapeutic options for elderly diabetic subjects: open label, randomized clinical trial of insulin glargine added to oral antidiabetic drugs versus increased dosage of oral antidiabetic drugs. | Acta diabetologica 20080301 |
Spermicidal activity of sulfonylureas and meglitinide analogues: role of intrasperm Ca2+ elevation. | The Journal of pharmacy and pharmacology 20080301 |
Design and development of gliclazide mucoadhesive microcapsules: in vitro and in vivo evaluation. | AAPS PharmSciTech 20080301 |
[Effects of Tangweian granule on 5-HT(2A)R in rat model with diabetic gastroparesis]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080301 |
Influence of the semisynthetic bile acid MKC on the ileal permeation of gliclazide in vitro in healthy and diabetic rats treated with probiotics. | Methods and findings in experimental and clinical pharmacology 20080301 |
Antiglycation effect of gliclazide on in vitro AGE formation from glucose and methylglyoxal. | Experimental biology and medicine (Maywood, N.J.) 20080201 |
Hypoglycemic effects of a sesquiterpene glycoside isolated from leaves of loquat (Eriobotrya japonica (Thunb.) Lindl.). | Phytomedicine : international journal of phytotherapy and phytopharmacology 20080101 |
Decreased in vivo oxidative stress and decreased platelet activation following metformin treatment in newly diagnosed type 2 diabetic subjects. | Diabetes/metabolism research and reviews 20080101 |
Evaluation of gliclazide ability to attenuate the hyperglycaemic 'memory' induced by high glucose in isolated human endothelial cells. | Diabetes/metabolism research and reviews 20080101 |
Development of extended zero-order release gliclazide tablets by central composite design. | Drug development and industrial pharmacy 20080101 |
Probiotic treatment reduces blood glucose levels and increases systemic absorption of gliclazide in diabetic rats. | European journal of drug metabolism and pharmacokinetics 20080101 |
Influence of the semisynthetic bile acid (MKC) on the ileal permeation of gliclazide in healthy and diabetic rats. | Pharmacological reports : PR 20080101 |
Vascular and renal benefits are additive using intensive blood pressure control and incremental glucose control in type 2 diabetic patients. | Cardiovascular journal of Africa 20080101 |
The influence of 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate on gliclazide pharmacokinetics and glucose levels in a rat model of diabetes. | European journal of drug metabolism and pharmacokinetics 20080101 |
Liquid chromatography--mass spectrometry method for the determination of gliclazide in human plasma and application to a pharmacokinetic study of gliclazide sustained release tablets. | Arzneimittel-Forschung 20080101 |
Gliclazide inhibits proliferation but stimulates differentiation of white and brown adipocytes. | Journal of biochemistry 20071101 |
Identification of the human cytochromes P450 catalysing the rate-limiting pathways of gliclazide elimination. | British journal of clinical pharmacology 20071001 |
The influence of hydro-alcoholic media on hypromellose matrix systems. | Drug development and industrial pharmacy 20071001 |
[Advanced credit: patient enrolling and therapy initiation in the ADVANCE trial]. | Orvosi hetilap 20070930 |
Are sulphonylureas all the same? A cohort study on cardiovascular and cancer-related mortality. | Diabetes/metabolism research and reviews 20070901 |
'Warm-up' phenomenon in diabetic patients with stable angina treated with diet or sulfonylureas. | Coronary artery disease 20070901 |
Long-term effects of pioglitazone versus gliclazide on hepatic and humoral coagulation factors in patients with type 2 diabetes. | Diabetes & vascular disease research 20070901 |
Effects of glibenclamide, glimepiride, and gliclazide on ischemic preconditioning in rat heart. | Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20070901 |
Controlling of systemic absorption of gliclazide through incorporation into alginate beads. | International journal of pharmaceutics 20070816 |
Comparisons between the beneficial effects of different sulphonylurea treatments on ischemia-induced retinal neovascularization. | Free radical biology & medicine 20070801 |
Association of sulfonylurea receptor 1 genotype with therapeutic response to gliclazide in type 2 diabetes. | Diabetes research and clinical practice 20070701 |
Influence of CYP2C9 and CYP2C19 genetic polymorphisms on pharmacokinetics of gliclazide MR in Chinese subjects. | British journal of clinical pharmacology 20070701 |
Gliclazide: pharmacokinetic-pharmacodynamic relationships in rats. | Biopharmaceutics & drug disposition 20070701 |
Nateglinide or gliclazide in combination with metformin for treatment of patients with type 2 diabetes mellitus inadequately controlled on maximum doses of metformin alone: 1-year trial results. | Diabetes, obesity & metabolism 20070701 |
In-vitro and in-vivo correlation for two gliclazide extended-release tablets. | The Journal of pharmacy and pharmacology 20070701 |
Development of a RP-HPLC method for screening potentially counterfeit anti-diabetic drugs. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070615 |
New insights from ADVANCE. | Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20070601 |
Insulinoma causing hypoglycemia in a patient with type 2 diabetes. | Journal of the Formosan Medical Association = Taiwan yi zhi 20070501 |
Mixture modeling for the detection of subpopulations in a pharmacokinetic/pharmacodynamic analysis. | Journal of pharmacokinetics and pharmacodynamics 20070401 |
Gliclazide protects human islet beta-cells from apoptosis induced by intermittent high glucose. | Diabetes/metabolism research and reviews 20070301 |
A bioequivalence study of gliclazide based on quantification by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry. | International journal of clinical pharmacology and therapeutics 20070301 |
Comparison of the solubility and dissolution rate between gliclazide solid complex and its nanospheres. | Drug development and industrial pharmacy 20070301 |
Dual aetiologies for hyperinsulinaemic hypoglycaemia in one patient. | Hong Kong medical journal = Xianggang yi xue za zhi 20070201 |
Preparation and in vitro/in vivo evaluation of gliclazide loaded Eudragit nanoparticles as a sustained release carriers. | Drug development and industrial pharmacy 20070201 |
Beneficial effects of gliclazide modified release compared with glibenclamide on endothelial activation and low-grade inflammation in patients with type 2 diabetes. | Diabetes, obesity & metabolism 20070101 |
The mushroom Agaricus Blazei Murill in combination with metformin and gliclazide improves insulin resistance in type 2 diabetes: a randomized, double-blinded, and placebo-controlled clinical trial. | Journal of alternative and complementary medicine (New York, N.Y.) 20070101 |
Impact of the short-term, intense exercise on postprandial glycemia in type 2 diabetic patients treated with gliclazide. | Journal of diabetes and its complications 20070101 |
In vivo and in vitro evaluation of a solid dispersion system of gliclazide:PEG 6000. | PDA journal of pharmaceutical science and technology 20070101 |
A case of mistaken identity. | Hong Kong medical journal = Xianggang yi xue za zhi 20061201 |
Effect of Kaiyu Qingwei Jianji on the morphometry and residual strain distribution of small intestine in experimental diabetic rats. | World journal of gastroenterology 20061128 |
Association of gliclazide and left ventricular mass in type 2 diabetic patients. | Diabetes research and clinical practice 20061101 |
Actions of ZD0947, a novel ATP-sensitive K+ channel opener, on membrane currents in human detrusor myocytes. | British journal of pharmacology 20061101 |
Activation of nicotinamide adenine dinucleotide phosphate (reduced form) oxidase by advanced glycation end products links oxidative stress to altered retinal vascular endothelial growth factor expression. | Metabolism: clinical and experimental 20061101 |
Effects of isopropyl palmitate on the skin permeation of drugs. | Biological & pharmaceutical bulletin 20061101 |
Application of monolithic column in quantification of gliclazide in human plasma by liquid chromatography. | Journal of pharmaceutical and biomedical analysis 20061011 |
Simultaneous estimation of six anti-diabetic drugs--glibenclamide, gliclazide, glipizide, pioglitazone, repaglinide and rosiglitazone: development of a novel HPLC method for use in the analysis of pharmaceutical formulations and its application to human plasma assay. | Biomedical chromatography : BMC 20061001 |
Influence of nicorandil on the pharmacodynamics and pharmacokinetics of gliclazide in rats and rabbits. | Molecular and cellular biochemistry 20061001 |
Effect of gliclazide modified release on adiponectin, interleukin-6, and tumor necrosis factor-alpha plasma levels in individuals with type 2 diabetes mellitus. | Current medical research and opinion 20061001 |
Effect of gliclazide on DNA damage in human peripheral blood lymphocytes and insulinoma mouse cells. | Chemico-biological interactions 20060925 |
Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide. | Pharmaceutical research 20060901 |
Gliclazide treatment lowers serum ICAM-1 levels in poorly controlled type 2 diabetic patients. | Diabetes & metabolism 20060901 |
Clinical observation on effect of Kaixin capsule in treating 40 patients with diabetic myocardial ischemia. | Chinese journal of integrative medicine 20060901 |
ADVANCE: breaking new ground in type 2 diabetes. | Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20060801 |
Antidiabetic activity of an ethanol extract obtained from the stem bark of Psidium guajava (Myrtaceae). | Die Pharmazie 20060801 |
[Rhabdomyolysis induced by fenofibrate monotherapy]. | La Revue de medecine interne 20060701 |
Is it time to re-assess the role of gliclazide? Targeting insulin resistance in type 2 diabetes patients suboptimally controlled with insulin. | Postgraduate medical journal 20060701 |
Comparison of nateglinide and gliclazide in combination with metformin, for treatment of patients with Type 2 diabetes mellitus inadequately controlled on maximum doses of metformin alone. | Diabetic medicine : a journal of the British Diabetic Association 20060701 |
A mechanism-based disease progression model for comparison of long-term effects of pioglitazone, metformin and gliclazide on disease processes underlying Type 2 Diabetes Mellitus. | Journal of pharmacokinetics and pharmacodynamics 20060601 |
Gliclazide protects 3T3L1 adipocytes against insulin resistance induced by hydrogen peroxide with restoration of GLUT4 translocation. | Metabolism: clinical and experimental 20060601 |
Gliclazide inhibits differentiation-associated biologic events in human monocyte-derived macrophages. | Metabolism: clinical and experimental 20060601 |
Effects of gliclazide beyond metabolic control. | Metabolism: clinical and experimental 20060501 |
Lymphocyte ecto-5'-nucleotidase in obese type 2 diabetic patients treated with gliclazide. | Diabetes & metabolism 20060401 |
Double-blind, randomized, multicentre study of the efficacy and safety of gliclazide-modified release in the treatment of Chinese type 2 diabetic patients. | Diabetes, obesity & metabolism 20060301 |
Comparison of glycaemic control over 1 year with pioglitazone or gliclazide in patients with Type 2 diabetes. | Diabetic medicine : a journal of the British Diabetic Association 20060301 |
Anti-diabetic and hypolipidemic effects of aqueous-extract from the flower of Inula japonica in alloxan-induced diabetic mice. | Biological & pharmaceutical bulletin 20060301 |
Influence of selenium (antioxidant) on gliclazide induced hypoglycaemia/anti hyperglycaemia in normal/alloxan-induced diabetic rats. | Molecular and cellular biochemistry 20060201 |
Comparison of the antioxidant and vascular effects of gliclazide and glibenclamide in Type 2 diabetic patients: a randomized crossover study. | Journal of diabetes and its complications 20060101 |
Three-year mortality in diabetic patients treated with different combinations of insulin secretagogues and metformin. | Diabetes/metabolism research and reviews 20060101 |
Development and validation of a new high-performance liquid chromatography method for the determination of gliclazide and repaglinide in pharmaceutical formulations. | Journal of AOAC International 20060101 |
Single and multiple dose bioequivalence evaluation of two brands of gliclazide modified release tablets in healthy Chinese male volunteers. | Arzneimittel-Forschung 20060101 |
The effectiveness of various doses of octreotide for sulfonylurea-induced hypoglycemia after overdose. | Advances in therapy 20060101 |
Secondary sulfonylurea failure: comparison of period until insulin treatment between diabetic patients treated with gliclazide and glibenclamide. | Diabetes research and clinical practice 20051201 |
Activation of KATP channels by H2S in rat insulin-secreting cells and the underlying mechanisms. | The Journal of physiology 20051201 |
Long-term effects on lipids and lipoproteins of pioglitazone versus gliclazide addition to metformin and pioglitazone versus metformin addition to sulphonylurea in the treatment of type 2 diabetes. | Diabetologia 20051201 |
The DIACOM study (effect of DosIng frequency of oral Antidiabetic agents on the COMpliance and biochemical control of type 2 diabetes). | Diabetes, obesity & metabolism 20051101 |
Simultaneous determination of metformin and gliclazide in human plasma by liquid chromatography-tandem mass spectrometry: application to a bioequivalence study of two formulations in healthy volunteers. | Journal of mass spectrometry : JMS 20051101 |
[The multi-level Meta analysis model combining individual level data with aggregative level data]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20051101 |
Safety and tolerability of pioglitazone, metformin, and gliclazide in the treatment of type 2 diabetes. | Diabetes research and clinical practice 20051001 |
Synthesis and characterization of gliclazide complexes of magnesium, calcium, chromium, manganese, iron, nickel, copper, zinc and cadmium salts. | Pakistan journal of pharmaceutical sciences 20051001 |
[A multicenter clinic study of slow-release-gliclazide in type 2 diabetes mellitus]. | Zhonghua yi xue za zhi 20050928 |
High-performance liquid chromatography with electrochemical detection for analysis of gliclazide in plasma. | Journal of chromatography. A 20050923 |
Determination of aminoheterocycle and azabicycle in gliclazide bulk by capillary zone electrophoresis with amperometric detection. | Journal of pharmaceutical and biomedical analysis 20050915 |
Management of diabetes during Ramadan. | Diabetic medicine : a journal of the British Diabetic Association 20050901 |
Gliclazide attenuates the intracellular Ca2+ changes induced in vitro by ischemia in the retinal slices of rats with streptozotocin-induced diabetes. | Current eye research 20050901 |
Changes in liver tests during 1-year treatment of patients with Type 2 diabetes with pioglitazone, metformin or gliclazide. | Diabetic medicine : a journal of the British Diabetic Association 20050801 |
Confusing tablets. | Lancet (London, England) 20050701 |
Long-term efficacy and tolerability of add-on pioglitazone therapy to failing monotherapy compared with addition of gliclazide or metformin in patients with type 2 diabetes. | Diabetologia 20050601 |
Pharmaceutical availability of gliclazide from selected matrix formulation tablets. | Medical science monitor : international medical journal of experimental and clinical research 20050601 |
Efficacy of glimepiride in Japanese type 2 diabetic subjects. | Diabetes research and clinical practice 20050601 |
The effect of gliclazide and glibenclamide on preconditioning of the human myocardium. | European journal of pharmacology 20050516 |
[Controversial therapeutic strategies in the treatment of type 2 diabetes mellitus]. | MMW Fortschritte der Medizin 20050428 |
A long-term comparison of pioglitazone and gliclazide in patients with Type 2 diabetes mellitus: a randomized, double-blind, parallel-group comparison trial. | Diabetic medicine : a journal of the British Diabetic Association 20050401 |
The development and validation of liquid chromatography method for the simultaneous determination of metformin and glipizide, gliclazide, glibenclamide or glimperide in plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050325 |
[54-year-old patient with type 2 diabetes mellitus and increased blood pressure values]. | Praxis 20050316 |
Comparison of pioglitazone and gliclazide in sustaining glycemic control over 2 years in patients with type 2 diabetes. | Diabetes care 20050301 |
Pioglitazone elicits long-term improvements in insulin sensitivity in patients with type 2 diabetes: comparisons with gliclazide-based regimens. | Diabetologia 20050301 |
The effect of short-term glycemic regulation with gliclazide and metformin on postprandial lipemia. | Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20050201 |
Long-term therapy with addition of pioglitazone to metformin compared with the addition of gliclazide to metformin in patients with type 2 diabetes: a randomized, comparative study. | Diabetes/metabolism research and reviews 20050101 |
Effect of repaglinide and gliclazide on postprandial control of endogenous glucose production. | Metabolism: clinical and experimental 20050101 |
Forearm vascular reactivity is differentially influenced by gliclazide and glibenclamide in chronically treated type 2 diabetic patients. | Clinical physiology and functional imaging 20050101 |
Gliclazide modified release. | Drugs 20050101 |
Effect of I-deprenyl and gliclazide on oxidant stress/antioxidant status and dna damage in a diabetic rat model. | Endocrine research 20050101 |
Effect of aqueous extract of Cyamopsis tetragonoloba Linn. beans on blood glucose level in normal and alloxan-induced diabetic rats. | Indian journal of experimental biology 20041201 |
Gliclazide modified release: results of a 2-year study in patients with type 2 diabetes. | Diabetes, obesity & metabolism 20041101 |
Metformin or gliclazide, rather than glibenclamide, attenuate progression of carotid intima-media thickness in subjects with type 2 diabetes. | Diabetologia 20041101 |
Effects of pioglitazone on the components of diabetic dyslipidaemia: results of double-blind, multicentre, randomised studies. | International journal of clinical practice 20041001 |
[Therapy objectives and daily practice--to which extent are blood sugar target values accessible in daily practice?]. | Praxis 20040929 |
Taurine block of cloned ATP-sensitive K+ channels with different sulfonylurea receptor subunits expressed in Xenopus laevis oocytes. | Biochemical pharmacology 20040901 |
Cardiovascular effects of treatment of type 2 diabetes with pioglitazone, metformin and gliclazide. | International journal of clinical practice 20040901 |
Studies on the glycemic and lipidemic effect of monopril and losartan in normal and diabetic rats. | Pharmacological research 20040801 |
GUIDE study: double-blind comparison of once-daily gliclazide MR and glimepiride in type 2 diabetic patients. | European journal of clinical investigation 20040801 |
Efficacy and safety of once daily gliclazide (20 mg/day) compared with nateglinide. | Endocrine journal 20040801 |
[2-year data of large clinical comparative studies. Type 2 diabetes: lasting metabolic control with pioglitazone]. | MMW Fortschritte der Medizin 20040722 |
[The efficacy and safety of 30 mg slow-released-gliclazide in type 2 diabetes mellitus]. | Zhonghua nei ke za zhi 20040701 |
Quantification of gliclazide by semi-micro high-performance liquid chromatography: application to a bioequivalence study of two formulations in healthy subjects. | Journal of pharmaceutical and biomedical analysis 20040629 |
Advanced glycation end-products increase monocyte adhesion to retinal endothelial cells through vascular endothelial growth factor-induced ICAM-1 expression: inhibitory effect of antioxidants. | Journal of leukocyte biology 20040601 |
Metformin attenuates progression of carotid arterial wall thickness in patients with type 2 diabetes. | Diabetes research and clinical practice 20040601 |
Normal pregnancy outcome following inadvertent exposure to rosiglitazone, gliclazide, and atorvastatin in a diabetic and hypertensive woman. | Reproductive toxicology (Elmsford, N.Y.) 20040601 |
Comparison of uptitration of gliclazide with the addition of rosiglitazone to gliclazide in patients with type 2 diabetes inadequately controlled on half-maximal doses of a sulphonylurea. | Acta diabetologica 20040601 |
Octreotide treatment for sulfonylurea-induced hypoglycaemia. | The Medical journal of Australia 20040517 |
Gliclazide at a lower concentration than therapeutic dose increases the sensitivity of insulin secretion to glucose in perfused rat pancreas. | Diabetes & metabolism 20040401 |
[Long-term HbA1c stable. Insulin sensitizer keeps diabetes in check]. | MMW Fortschritte der Medizin 20040325 |
Erosion induced controllable release of gliclazide encapsulated inside degradable polymeric particles. | Macromolecular bioscience 20040315 |
Signalling pathways involved in retinal endothelial cell proliferation induced by advanced glycation end products: inhibitory effect of gliclazide. | Diabetes, obesity & metabolism 20040301 |
NMDA receptor subunits 2A and 2B decrease and lipid peroxidation increase in the hippocampus of streptozotocin-diabetic rats: effects of insulin and gliclazide treatments. | The International journal of neuroscience 20040301 |
Radical scavenging effect of gliclazide in diabetic rats fed with a high cholesterol diet. | Kidney international 20040301 |
Effect of antidiabetic medications on microalbuminuria in patients with type 2 diabetes. | Metabolism: clinical and experimental 20040301 |
Myocardial protection from either ischaemic preconditioning or nicorandil is not blocked by gliclazide. | Cardiovascular drugs and therapy 20040301 |
[Compliance and optimisation of oral antidiabetic therapy. A longitudinal study]. | Presse medicale (Paris, France : 1983) 20040214 |
Phosphatidylinositol 3-kinase activation is required for sulfonylurea stimulation of glucose transport in rat skeletal muscle. | Endocrinology 20040201 |
Long-term glycaemic control with pioglitazone in patients with type 2 diabetes. | International journal of clinical practice 20040201 |
Favorable effects of pioglitazone and metformin compared with gliclazide on lipoprotein subfractions in overweight patients with early type 2 diabetes. | Diabetes care 20040101 |
Protective actions of gliclazide on high insulin-enhanced neutrophil-endothelial cell interactions through inhibition of mitogen activated protein kinase and protein kinase C pathways. | Microvascular research 20040101 |
Spectrophotometric determination of gliclazide in pharmaceuticals and biological fluids through ternary complex formation with eosin and palladium (II). | Farmaco (Societa chimica italiana : 1989) 20040101 |
The antidiabetic agent, gliclazide, reduces high insulin-enhanced neutrophil-transendothelial migration through direct effects on the endothelium. | Diabetes/metabolism research and reviews 20040101 |
NIDDM: new once-daily intervention for type 2 diabetes mellitus: Diaprel MR. | Romanian journal of internal medicine = Revue roumaine de medecine interne 20040101 |
[A prospective randomized study of sulphonylureas therapeutic interchange in patients with type 2 diabetes mellitus]. | Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20040101 |
Comparison of repaglinide vs. gliclazide in combination with bedtime NPH insulin in patients with Type 2 diabetes inadequately controlled with oral hypoglycaemic agents. | Diabetic medicine : a journal of the British Diabetic Association 20031101 |
Genetic cause of hyperglycaemia and response to treatment in diabetes. | Lancet (London, England) 20031018 |
Effect of rifampin on the pharmacokinetics and pharmacodynamics of gliclazide. | Clinical pharmacology and therapeutics 20031001 |
Monotherapy of type 2 diabetes with once-daily gliclazide modified release in primary care. | Diabetes research and clinical practice 20031001 |
[Medication of the month. Gliclazide modified release (Uni Diamicron)]. | Revue medicale de Liege 20031001 |
Reflex epilepsy and non-ketotic hyperglycemia. | Epileptic disorders : international epilepsy journal with videotape 20030901 |
Benefits of gliclazide in the atherosclerotic process: decrease in monocyte adhesion to endothelial cells. | Metabolism: clinical and experimental 20030801 |
Gliclazide modified release: A critical review of pharmacodynamic, metabolic, and vasoprotective effects. | Metabolism: clinical and experimental 20030801 |
Bioequivalence study of generic gliclazide and Diamicron formulations in healthy Thai male volunteers. | International journal of clinical pharmacology and therapeutics 20030701 |
The application of the convective diffusion model and the film equilibrium model to surfactant-facilitated dissolution of gliclazide. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030701 |
Pharmacokinetic and pharmacodynamic characterization of gliclazide in healthy volunteers. | Archives of pharmacal research 20030701 |
Functional involvement of sulphonylurea receptor (SUR) type 1 and 2B in the activity of pig urethral ATP-sensitive K+ channels. | British journal of pharmacology 20030601 |
Comparison of the micro- and macro-vascular effects of glimepiride and gliclazide in metformin-treated patients with Type 2 diabetes: a double-blind, crossover study. | British journal of clinical pharmacology 20030601 |
Diabetes and vascular disease: a new international trial. | Asian cardiovascular & thoracic annals 20030601 |
Urinary PC-1 and N-acetyl-beta-D-glucosaminidase activity in patients with type 2 diabetes treated with metformin, gliclazide or glibenclamide. | Annals of clinical biochemistry 20030501 |
Study of the solubilization of gliclazide by aqueous micellar solutions. | Journal of pharmaceutical sciences 20030401 |
Gliclazide protects pancreatic beta-cells from damage by hydrogen peroxide. | Biochemical and biophysical research communications 20030328 |
A simple and sensitive HPLC method for determination of gliclazide in human serum. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030305 |
Population PKPD modelling of the long-term hypoglycaemic effect of gliclazide given as a once-a-day modified release (MR) formulation. | British journal of clinical pharmacology 20030201 |
Differential effects of sulphonylureas on the vasodilatory response evoked by K(ATP) channel openers. | Fundamental & clinical pharmacology 20030201 |
Diabetes mellitus and weight control: differences of respiratory quotient in type 2 diabetic obese subjects receiving sulfonylureas and non-diabetic obese controls. | Nutrition (Burbank, Los Angeles County, Calif.) 20030201 |
Severe relapsing sulphonylurea-induced hypoglycaemia: a diagnostic and therapeutic challenge. | Postgraduate medical journal 20030201 |
The mechanisms of inhibitory actions of gliclazide on neutrophils-endothelial cells adhesion and surface expression of endothelial adhesion molecules mediated by a high glucose concentration. | Journal of diabetes and its complications 20030101 |
Effects of inhibition of ATP-sensitive potassium channels on metabolic vasodilation in the human forearm. | Clinical science (London, England : 1979) 20030101 |
Effects of sulfonylureas on K(ATP) channel-dependent vasodilation. | Journal of diabetes and its complications 20030101 |
Monocyte adhesion in diabetic angiopathy: effects of free-radical scavenging. | Journal of diabetes and its complications 20030101 |
Diabetic endothelial dysfunction: effect of free radical scavenging in Type 2 diabetic patients. | Journal of diabetes and its complications 20030101 |
Spectrofluorimetric and spectrophotometric determination of gliclazide in pharmaceuticals by derivatization with 4-chloro-7-nitrobenzo-2-oxa-1,3-diazole. | Journal of AOAC International 20030101 |
Addition of rosiglitazone to existing sulfonylurea treatment in chinese patients with type 2 diabetes and exposure to hepatitis B or C. | Diabetes technology & therapeutics 20030101 |
Gliclazide increases insulin receptor tyrosine phosphorylation but not p38 phosphorylation in insulin-resistant skeletal muscle cells. | The Journal of experimental biology 20021201 |
Interaction of the cytosolic domains of the Kir6.2 subunit of the K(ATP) channel is modulated by sulfonylureas. | Diabetes 20021201 |
Gliclazide directly inhibits arginine-induced glucagon release. | Diabetes 20021201 |
Combination therapy of alpha-glucosidase inhibitor and a sulfonylurea compound prolongs the duration of good glycemic control. | Metabolism: clinical and experimental 20021201 |
Hypoglycaemic activity of Alpinia galanga rhizome and its extracts in rabbits. | Fitoterapia 20021201 |
Eudragit NE30D based metformin/gliclazide extended release tablets: formulation, characterisation and in vitro release studies. | Chemical & pharmaceutical bulletin 20021101 |
Effect of gliclazide on islet transplants. | Transplantation proceedings 20021101 |
Remodelling of zero-stress state of small intestine in streptozotocin-induced diabetic rats. Effect of gliclazide. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20021001 |
Gliclazide improves anti-oxidant status and nitric oxide-mediated vasodilation in Type 2 diabetes. | Diabetic medicine : a journal of the British Diabetic Association 20020901 |
A novel simple method for the investigation of drug binding to the K(ATP) channel sulfonylurea receptor. | Analytical biochemistry 20020815 |
Bioequivalence evaluation of two brands of gliclazide 80 mg tablets (Glyzide & Diamicron)--in healthy human volunteers. | Biopharmaceutics & drug disposition 20020701 |
Oral hypoglycaemic agent failure. | Journal of the Indian Medical Association 20020701 |
Acute gliclazide administration enhances glucose and ketone body utilization in the perfused hind limb of normal and streptozotocin-diabetic rats. | Life sciences 20020628 |
Effect of pioglitazone on blood proinsulin levels in patients with type 2 diabetes mellitus. | Endocrine journal 20020601 |
Complete bioavailability and lack of food-effect on pharmacokinetics of gliclazide 30 mg modified release in healthy volunteers. | Biopharmaceutics & drug disposition 20020501 |
Gliclazide-induced acute hepatitis with hypersensitivity features. | Digestive diseases and sciences 20020501 |
Effective and selective prevention of retinal leukostasis in streptozotocin-induced diabetic rats using gliclazide. | Diabetologia 20020501 |
Studies on solubility and hypoglycemic activity of gliclazide beta-cyclodextrin-hydroxypropylmethylcellulose complexes. | Die Pharmazie 20020301 |
Does gliclazide stimulate first-phase, second-phase, or both phases of insulin release? | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020201 |
Gliclazide modified release. | Drugs 20020101 |
Advanced glycation end products increase, through a protein kinase C-dependent pathway, vascular endothelial growth factor expression in retinal endothelial cells. Inhibitory effect of gliclazide. | Journal of diabetes and its complications 20020101 |
Effect of ethanolic extract of Embelia ribes on dyslipidemia in diabetic rats. | International journal of experimental diabetes research 20020101 |
Regulation of glucose transporter 1 expression by gliclazide in rat L6 myoblasts. | Diabetes, nutrition & metabolism 20011201 |
Increments in insulin sensitivity during intensive treatment are closely correlated with decrements in glucocorticoid receptor mRNA in skeletal muscle from patients with Type II diabetes. | Clinical science (London, England : 1979) 20011101 |
Possible interaction between gliclazide, fluconazole and sulfamethoxazole resulting in severe hypoglycaemia. | British journal of clinical pharmacology 20011001 |
Study rationale and design of ADVANCE: action in diabetes and vascular disease--preterax and diamicron MR controlled evaluation. | Diabetologia 20010901 |
Acute and short-term administration of a sulfonylurea (gliclazide) increases pulsatile insulin secretion in type 2 diabetes. | Diabetes 20010801 |
Gliclazide produces high-affinity block of KATP channels in mouse isolated pancreatic beta cells but not rat heart or arterial smooth muscle cells. | Diabetologia 20010801 |
Glibenclamide vs gliclazide in reducing oxidative stress in patients of noninsulin dependent diabetes mellitus--a double blind randomized study. | The Journal of the Association of Physicians of India 20010801 |
Gliclazide decreases vascular smooth muscle cell dysfunction induced by cell-mediated oxidized low-density lipoprotein. | Metabolism: clinical and experimental 20010601 |
Gliclazide mainly affects insulin secretion in second phase of type 2 diabetes mellitus. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20010601 |
ATP-Sensitive potassium channels modulate glucose transport in cultured human skeletal muscle cells. | Endocrine journal 20010601 |
[Effects of gliclazide on blood rheology of diabetes Wistar rat]. | Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20010601 |
Characteristics of pancreatic beta-cell secretion in Type 2 diabetic patients treated with gliclazide and glibenclamide. | Diabetes research and clinical practice 20010501 |
ION-pair liquid chromatography technique for the estimation of metformin in its multicomponent dosage forms. | Journal of pharmaceutical and biomedical analysis 20010401 |
Sulfonylurea treatment of type 2 diabetic patients does not reduce the vasodilator response to ischemia. | Diabetes care 20010401 |
24-hour glycemic profile in type 2 diabetic patients treated with gliclazide modified release once daily. | Diabetes & metabolism 20010401 |
Effect of KAD-1229, a nonsulfonylurea hypoglycemic agent, on plasma glucose and insulin in streptozotocin-induced diabetic dogs. | Pharmacology 20010201 |
Gliclazide and bedtime insulin are more efficient than insulin alone for type 2 diabetic patients with sulfonylurea secondary failure. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20010101 |
Comparison of acarbose and gliclazide as first-line agents in patients with type 2 diabetes. | Current medical research and opinion 20010101 |
[Free radical scavenging activity of sulfonylureas: a clinical assessment of the effectiveness of gliclazide]. | Terapevticheskii arkhiv 20010101 |
Gliclazide-induced hepatitis, hemiplegia and dysphasia in a suicide attempt. | Journal of pediatric endocrinology & metabolism : JPEM 20010101 |
[Toxicological analysis in the dawn of the third millenium]. | Annales de biologie clinique 20010101 |
[Recurrent toxic severe hypoglycemias]. | Annales de biologie clinique 20010101 |
Determination of gliclazide in pharmaceutical preparations by capillary gas chromatography with cool on-column injection and elimination of the matrix effect. | Journal of AOAC International 20010101 |
[Antioxidant and anti-AGE therapeutics: evaluation and perspectives]. | Journal de la Societe de biologie 20010101 |
Gliclazide-induced acute hepatitis. | European journal of gastroenterology & hepatology 20000101 |
Cardiovascular effects of conventional sulfonylureas and glimepiride. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 19960901 |
Possible gliclazide-induced water retention with azotemia. | Internal medicine (Tokyo, Japan) 19940301 |