Home Aldehydes 2-Amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde

2-Amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde

CAS No.:
712-30-1
Catalog Number:
AG005WDC
Molecular Formula:
C7H5N5O2
Molecular Weight:
191.1469
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥98%
1 week
United States
$229
- +
5mg
≥98%
1 week
United States
$779
- +
10mg
≥98%
1 week
United States
$1230
- +
Product Description
Catalog Number:
AG005WDC
Chemical Name:
2-Amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde
CAS Number:
712-30-1
Molecular Formula:
C7H5N5O2
Molecular Weight:
191.1469
MDL Number:
MFCD00038691
IUPAC Name:
2-amino-4-oxo-3H-pteridine-6-carbaldehyde
InChI:
InChI=1S/C7H5N5O2/c8-7-11-5-4(6(14)12-7)10-3(2-13)1-9-5/h1-2H,(H3,8,9,11,12,14)
InChI Key:
LLJAQDVNMGLRBD-UHFFFAOYSA-N
SMILES:
O=Cc1cnc2c(n1)c(O)nc(n2)N
Properties
Complexity:
303  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
191.044g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
191.15g/mol
Monoisotopic Mass:
191.044g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
110A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.6  
Literature
Title Journal
Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells. The Journal of experimental medicine 20131021
MR1 presents microbial vitamin B metabolites to MAIT cells. Nature 20121129
Photosensitizing properties of biopterin and its photoproducts using 2'-deoxyguanosine 5'-monophosphate as an oxidizable target. Physical chemistry chemical physics : PCCP 20120907
Hypoxia-inducible factor 1 protects hypoxic astrocytes against glutamate toxicity. ASN neuro 20120101
Regulation of xanthine oxidase activity by substrates at active sites via cooperative interactions between catalytic subunits: implication to drug pharmacokinetics. Current medicinal chemistry 20110101
The self-organizing fractal theory as a universal discovery method: the phenomenon of life. Theoretical biology & medical modelling 20110101
Regulation of hypoxia inducible factor-1α expression by the alteration of redox status in HepG2 cells. Journal of experimental & clinical cancer research : CR 20110101
Mechanism of photooxidation of folic acid sensitized by unconjugated pterins. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20101201
Substituent effects of pterin derivatives on singlet oxygen scavenging activity. Biological & pharmaceutical bulletin 20100101
Methanol assimilation in Methylobacterium extorquens AM1: demonstration of all enzymes and their regulation. PloS one 20100101
Mechanism of Substrate and Inhibitor Binding of Rhodobacter capsulatus Xanthine Dehydrogenase. The Journal of biological chemistry 20090327
New results on the photochemistry of biopterin and neopterin in aqueous solution. Photochemistry and photobiology 20090101
Reactive oxygen species generation through NADH oxidation by pterin derivatives. Nucleic acids symposium series (2004) 20080101
Lipoic acid and 6-formylpterin reduce potentiation of noise-induced hearing loss by carbon monoxide: preliminary investigation. Journal of rehabilitation research and development 20080101
Inhibitory effect of 6-formylpterin on HIF-1alpha protein accumulation. Biological & pharmaceutical bulletin 20071101
Synthesis of 6-formylpterin nucleoside analogs and their ROS generation activities in the presence of NADH in the dark. Organic & biomolecular chemistry 20071021
Folate salvage in plants: pterin aldehyde reduction is mediated by multiple non-specific aldehyde reductases. The Plant journal : for cell and molecular biology 20070801
Singlet oxygen (O2(1Deltag)) quenching by dihydropterins. The journal of physical chemistry. A 20070524
Pterin and folate salvage. Plants and Escherichia coli lack capacity to reduce oxidized pterins. Plant physiology 20070301
Reactive oxygen species generation through NADH oxidation by 6-formylpterin derivatives in the dark. Biochemical and biophysical research communications 20070223
Gene expression in enhanced apoptosis of human lymphoma U937 cells treated with the combination of different free radical generators and hyperthermia. Free radical research 20070101
Comparative genomics of bacterial and plant folate synthesis and salvage: predictions and validations. BMC genomics 20070101
Chemical natures of 6-formylpterin nucleoside analogs. Nucleic acids symposium series (2004) 20070101
Folic acid as a Fenton-modulator: possible physiological implication. Medicinal chemistry (Shariqah (United Arab Emirates)) 20060701
Novel 6-formylpterin derivatives: chemical synthesis and O2 to ROS conversion activities. Organic & biomolecular chemistry 20060507
Chemical natures and application of 6-formylpterin derivatives. Nucleic acids symposium series (2004) 20060101
Protective effects of intracellular reactive oxygen species generated by 6-formylpterin on tumor necrosis factor-alpha-induced apoptotic cell injury in cultured rat hepatocytes. Life sciences 20050708
Ultraviolet photodegradation of folic acid. Journal of photochemistry and photobiology. B, Biology 20050701
A hydrogen peroxide-generating agent, 6-formylpterin, enhances heat-induced apoptosis. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20050501
Hydrogen bond removal of pterin derivative whose structure is similar to nucleic acid bases. Nucleic acids symposium series (2004) 20050101
Cooperative catalysis in the homodimer subunits of xanthine oxidase. Biochemistry 20040427
Enhancement of radiation-induced apoptosis by 6-formylpterin. Free radical research 20040401
Effects of intracellular reactive oxygen species generated by 6-formylpterin on T cell functions. Biochemical pharmacology 20040315
Quenching of the fluorescence of pterin derivatives by anions. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20040201
6-Formylpterin protects retinal neurons from transient ischemia-reperfusion injury in rats: a morphological and immunohistochemical study. Neuropathology : official journal of the Japanese Society of Neuropathology 20030901
Effects of 6-formylpterin as an internal source of hydrogen peroxide on cell death of human peripheral blood leukocytes. Life sciences 20030530
Singlet oxygen (1deltag) production by pterin derivatives in aqueous solutions. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20030301
Syntheses of labeled vitamers of folic acid to be used as internal standards in stable isotope dilution assays. Journal of agricultural and food chemistry 20020814
Fluorescence of pterin, 6-formylpterin, 6-carboxypterin and folic acid in aqueous solution: pH effects. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20020601
Oxidative stress in vitiligo: photo-oxidation of pterins produces H(2)O(2) and pterin-6-carboxylic acid. Biochemical and biophysical research communications 20020412
6-formylpterin intracellularly generates hydrogen peroxide and restores the impaired bactericidal activity of human neutrophils. Biochemical and biophysical research communications 20011123
6-formylpterin, a xanthine oxidase inhibitor, intracellularly generates reactive oxygen species involved in apoptosis and cell proliferation. Free radical biology & medicine 20010201
Properties