Home Halogens Benzene,1,1'-(2,2,2-trichloroethylidene)bis[4-methoxy-

Benzene,1,1'-(2,2,2-trichloroethylidene)bis[4-methoxy-

CAS No.:
72-43-5
Catalog Number:
AG005TJD
Molecular Formula:
C16H15Cl3O2
Molecular Weight:
345.6481
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25g
>95.0%(GC)
1 week
United States
$182
- +
Product Description
Catalog Number:
AG005TJD
Chemical Name:
Benzene,1,1'-(2,2,2-trichloroethylidene)bis[4-methoxy-
CAS Number:
72-43-5
Molecular Formula:
C16H15Cl3O2
Molecular Weight:
345.6481
MDL Number:
MFCD00000803
IUPAC Name:
1-methoxy-4-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]benzene
InChI:
InChI=1S/C16H15Cl3O2/c1-20-13-7-3-11(4-8-13)15(16(17,18)19)12-5-9-14(21-2)10-6-12/h3-10,15H,1-2H3
InChI Key:
IAKOZHOLGAGEJT-UHFFFAOYSA-N
SMILES:
COc1ccc(cc1)C(C(Cl)(Cl)Cl)c1ccc(cc1)OC
EC Number:
200-779-9
UNII:
RIA79UD69L
NSC Number:
8945
RTECS Number:
KJ3675000
Properties
Complexity:
279  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
344.014g/mol
Formal Charge:
0
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
345.644g/mol
Monoisotopic Mass:
344.014g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
18.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
5.1  
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A simple and rapid matrix-assisted laser desorption/ionization time of flight mass spectrometry method to screen fish plasma samples for estrogen-responsive biomarkers. Environmental toxicology and chemistry 20080501
In utero exposure to low doses of environmental pollutants disrupts fetal ovarian development in sheep. Molecular human reproduction 20080501
Reductive dechlorination of methoxychlor and DDT by human intestinal bacterium Eubacterium limosum under anaerobic conditions. Archives of environmental contamination and toxicology 20080401
Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism. Chemical research in toxicology 20080401
In vivo and in vitro effects of the organochlorine pesticides DDT, TCPM, methoxychlor, and lindane on the female reproductive tract of mammals: a review. Reproductive toxicology (Elmsford, N.Y.) 20080401
Effects of the pesticide methoxychlor on gene expression in the liver and testes of the male largemouth bass (Micropterus salmoides). Aquatic toxicology (Amsterdam, Netherlands) 20080326
Pesticides removal in the process of drinking water production. Chemosphere 20080301
Mechanisms of interaction of endocrine-disrupting chemicals with glutamate-evoked secretion of gonadotropin-releasing hormone. Toxicological sciences : an official journal of the Society of Toxicology 20080301
Effects of possible endocrine disruptors on MyD88-independent TLR4 signaling. FEMS immunology and medical microbiology 20080301
Chemical contaminants, health indicators, and reproductive biomarker responses in fish from rivers in the Southeastern United States. The Science of the total environment 20080215
Removal of endosulfan and methoxychlor from water on carbon slurry. Environmental science & technology 20080201
Glucuronidation and sulfonation, in vitro, of the major endocrine-active metabolites of methoxychlor in the channel catfish, Ictalurus punctatus, and induction following treatment with 3-methylcholanthrene. Aquatic toxicology (Amsterdam, Netherlands) 20080131
Stimulation of transactivation of the largemouth bass estrogen receptors alpha, beta-a, and beta-b by methoxychlor and its mono- and bis-demethylated metabolites in HepG2 cells. The Journal of steroid biochemistry and molecular biology 20080101
The methoxychlor metabolite, HPTE, directly inhibits the catalytic activity of cholesterol side-chain cleavage (P450scc) in cultured rat ovarian cells. Reproductive toxicology (Elmsford, N.Y.) 20080101
Household vacuum cleaners vs. the high-volume surface sampler for collection of carpet dust samples in epidemiologic studies of children. Environmental health : a global access science source 20080101
The herbicide atrazine activates endocrine gene networks via non-steroidal NR5A nuclear receptors in fish and mammalian cells. PloS one 20080101
Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice. BMC physiology 20080101
Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease. Molecular brain 20080101
Transgenerational epigenetic programming of the brain transcriptome and anxiety behavior. PloS one 20080101
Antioxidant systems and oxidative stress in the testes. Oxidative medicine and cellular longevity 20080101
Online in situ analysis of selected semi-volatile organic compounds in water by automated microscale solid-phase extraction with large-volume injection/gas chromatography/mass spectrometry. Journal of chromatography. A 20071228
Occurrence and distribution of persistent trace organics in rainwater in an urban region (India). Bulletin of environmental contamination and toxicology 20071201
Metabolic profiling of endocrine-disrupting compounds by on-line cytochrome p450 bioreaction coupled to on-line receptor affinity screening. Chemical research in toxicology 20071201
Human exposure to endocrine-disrupting chemicals and prenatal risk factors for cryptorchidism and hypospadias: a nested case-control study. Environmental health perspectives 20071201
Estrogen sensitivity of target genes and expression of nuclear receptor co-regulators in rat prostate after pre- and postnatal exposure to the ultraviolet filter 4-methylbenzylidene camphor. Environmental health perspectives 20071201
Endocrine-disrupting potential of bisphenol A, bisphenol A dimethacrylate, 4-n-nonylphenol, and 4-n-octylphenol in vitro: new data and a brief review. Environmental health perspectives 20071201
Activity of xenoestrogens at nanomolar concentrations in the E-Screen assay. Environmental health perspectives 20071201
Ten years of mixing cocktails: a review of combination effects of endocrine-disrupting chemicals. Environmental health perspectives 20071201
Mixture effects of estrogenic compounds on proliferation and pS2 expression of MCF-7 human breast cancer cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20071101
Organochlorine pesticide contamination in three bird species of the Embalse La Florida water reservoir in the semiarid midwest of Argentina. The Science of the total environment 20071015
Effects of xenoestrogens on the differentiation of behaviorally-relevant neural circuits. Frontiers in neuroendocrinology 20071001
Multi-residue determination of pesticides in water using multi-walled carbon nanotubes solid-phase extraction and gas chromatography-mass spectrometry. Journal of chromatography. A 20070921
Developmental exposure to low-dose estrogenic endocrine disruptors alters sex differences in exploration and emotional responses in mice. Hormones and behavior 20070901
Environmental exposures and gene regulation in disease etiology. Environmental health perspectives 20070901
The pesticide methoxychlor decreases myotube formation in cell culture by slowing myoblast proliferation. Toxicology in vitro : an international journal published in association with BIBRA 20070801
Methoxychlor suppresses the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible CYP1A1 expression in murine Hepa-1c1c7 cells. Journal of toxicology and environmental health. Part A 20070801
Methoxychlor and its metabolites inhibit growth and induce atresia of baboon antral follicles. Toxicologic pathology 20070801
Determination of organochlorine pesticides in ground water samples using solid-phase microextraction by gas chromatography-electron capture detection. Talanta 20070731
Organochlorine pesticides in placentas from Southern Spain and some related factors. Placenta 20070701
Chemical contaminants, health indicators, and reproductive biomarker responses in fish from the Colorado River and its tributaries. The Science of the total environment 20070601
Organochlorine pesticides in freshwater fish from the Zagreb area. Arhiv za higijenu rada i toksikologiju 20070601
Organochlorine pesticides in seafood products from southern China and health risk assessment. Environmental toxicology and chemistry 20070601
Estradiol and Bisphenol A stimulate androgen receptor and estrogen receptor gene expression in fetal mouse prostate mesenchyme cells. Environmental health perspectives 20070601
Residues of persistent organochlorine contaminants in southern elephant seals (Mirounga leonina) from Elephant Island, Antarctica. Environmental science & technology 20070601
Toxic effects of methoxychlor in rat striatum: modifications in several neurotransmitters. Journal of physiology and biochemistry 20070601
Residues of organochlorine pesticides in near shore waters of LaiZhou Bay and JiaoZhou Bay, Shandong Peninsula, China. Chemosphere 20070501
Residues of organochlorine pesticides in fish from the Gomti river, India. Bulletin of environmental contamination and toxicology 20070501
[Simultaneous determination of nine organochlorine pesticide residues in textile by high performance liquid chromatography]. Se pu = Chinese journal of chromatography 20070501
Estrogenic effects of mixtures of phyto- and synthetic chemicals on uterine growth of prepubertal rats. Toxicology letters 20070425
Calbindin-D9k mRNA expression in the rat uterus following exposure to methoxychlor: a comparison of oral and subcutaneous exposure. The Journal of reproduction and development 20070401
From mother to child: investigation of prenatal and postnatal exposure to persistent bioaccumulating toxicants using breast milk and placenta biomonitoring. Chemosphere 20070401
Perinatal bisphenol A exposure increases estrogen sensitivity of the mammary gland in diverse mouse strains. Environmental health perspectives 20070401
Residues of organochlorinated pesticides in soils from the Czech Republic. Environmental pollution (Barking, Essex : 1987) 20070301
Estrogen receptor independent neurotoxic mechanism of bisphenol A, an environmental estrogen. Journal of veterinary science 20070301
Persistent organochlorine pesticide residues in soil and surface water of northern Indo-Gangetic alluvial plains. Environmental monitoring and assessment 20070201
Metals and organochlorine pesticides in caudal scutes of crocodiles from Belize and Costa Rica. The Science of the total environment 20070201
Exposure of young men to organochlorine pesticides in Southern Spain. Environmental research 20070101
A proteomic (SELDI-TOF-MS) approach to estrogen agonist screening. Toxicological sciences : an official journal of the Society of Toxicology 20070101
In silico prediction of pregnane X receptor activators by machine learning approaches. Molecular pharmacology 20070101
Appropriate 'housekeeping' genes for use in expression profiling the effects of environmental estrogens in fish. BMC molecular biology 20070101
Pesticide content in drinking water samples collected from orchard areas in central Poland. Annals of agricultural and environmental medicine : AAEM 20070101
Determining the transrepression activity of xenoestrogen on nuclear factor-kappa B in Cos-1 cells by estrogen receptor-alpha. International journal of toxicology 20070101
Developmental programming: differential effects of prenatal exposure to bisphenol-A or methoxychlor on reproductive function. Endocrinology 20061201
Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: a potential novel mechanism of endocrine disruption. The Journal of steroid biochemistry and molecular biology 20061201
Early postnatal methoxychlor exposure inhibits folliculogenesis and stimulates anti-Mullerian hormone production in the rat ovary. The Journal of endocrinology 20061201
Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line. Toxicology 20061110
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. Journal of molecular graphics & modelling 20061101
Organochlorine contaminants in complete clutches of Morelet's crocodile (Crocodylus moreletii) eggs from Belize. Environmental pollution (Barking, Essex : 1987) 20061101
The methoxychlor metabolite, 2,2-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane, inhibits steroidogenesis in rat ovarian granulosa cells in vitro. Reproductive toxicology (Elmsford, N.Y.) 20061101
Methoxychlor causes mitochondrial dysfunction and oxidative damage in the mouse ovary. Toxicology and applied pharmacology 20061101
Experimental parameters affecting sensitivity and specificity of a yeast assay for estrogenic compounds: results of an interlaboratory validation exercise. Analytical and bioanalytical chemistry 20061101
Fertile grounds of inquiry: environmental effects on human reproduction. Environmental health perspectives 20061101
Methoxychlor inhibits growth and induces atresia of antral follicles through an oxidative stress pathway. Toxicological sciences : an official journal of the Society of Toxicology 20061001
Effects of possible endocrine disrupting chemicals on bacterial component-induced activation of NF-kappaB. Biological & pharmaceutical bulletin 20061001
Agricultural pesticide use and hypospadias in eastern Arkansas. Environmental health perspectives 20061001
Analytical methods for PCBs and organochlorine pesticides in environmental monitoring and surveillance: a critical appraisal. Analytical and bioanalytical chemistry 20061001
Microwave-assisted extraction through an aqueous medium and simultaneous cleanup by partition on hexane for determining pesticides in agricultural soils by gas chromatography: a critical study. Analytica chimica acta 20060925
Methoxychlor metabolites may cause ovarian toxicity through estrogen-regulated pathways. Toxicological sciences : an official journal of the Society of Toxicology 20060901
Methoxychlor induces atresia of antral follicles in ERalpha-overexpressing mice. Toxicological sciences : an official journal of the Society of Toxicology 20060901
Activation of alpha- and beta-estrogen receptors by persistent pesticides in reporter cell lines. Life sciences 20060815
Evoecotoxicology: environmental changes and life features development during the evolutionary process-the record of the past at developmental stages of living organisms. Environmental health perspectives 20060801
PAH-DNA adducts in cord blood and fetal and child development in a Chinese cohort. Environmental health perspectives 20060801
Determination of organochlorine pesticides and polychlorinated biphenyls in chicken eggs by matrix solid phase dispersion. Analytica chimica acta 20060728
Persistent pesticides in human breast milk and cryptorchidism. Environmental health perspectives 20060701
Demethylation of the pesticide methoxychlor in liver and intestine from untreated, methoxychlor-treated, and 3-methylcholanthrene-treated channel catfish (Ictalurus punctatus): evidence for roles of CYP1 and CYP3A family isozymes. Drug metabolism and disposition: the biological fate of chemicals 20060601
Endocrine regulation of HOX genes. Endocrine reviews 20060601
NTP multigenerational study of environmental estrogens. Environmental health perspectives 20060601
Estrogenic effects in vitro and in vivo of the fungicide fenarimol. Toxicology letters 20060525
Altered mammary gland development in male rats exposed to genistein and methoxychlor. Toxicological sciences : an official journal of the Society of Toxicology 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Status of antioxidant defense system and expression of toxicant responsive genes in striatum of maneb- and paraquat-induced Parkinson's disease phenotype in mouse: mechanism of neurodegeneration. Brain research 20060407
Rapid action of pesticides on cytosolic calcium concentrations in cultures of human umbilical vein endothelial cells. Reproductive toxicology (Elmsford, N.Y.) 20060401
Perinatal immunotoxicity: why adult exposure assessment fails to predict risk. Environmental health perspectives 20060401
Endocrine disrupting contaminants--beyond the dogma. Environmental health perspectives 20060401
Pesticide mixtures, endocrine disruption, and amphibian declines: are we underestimating the impact? Environmental health perspectives 20060401
Screening and testing for endocrine disruption in fish-biomarkers as 'signposts,' not 'traffic lights,' in risk assessment. Environmental health perspectives 20060401
Modeling the demographic effects of endocrine disruptors. Environmental health perspectives 20060401
Viewpoint: Policy requirements for protecting wildlife from endocrine disruptors. Environmental health perspectives 20060401
Epigenetics: the science of change. Environmental health perspectives 20060301
Reproductive abnormalities in adult male mice following preimplantation exposures to estradiol or pesticide methoxychlor. Reproductive toxicology (Elmsford, N.Y.) 20060201
In vivo exposure of young adult male rats to methoxychlor reduces serum testosterone levels and ex vivo Leydig cell testosterone formation and cholesterol side-chain cleavage activity. Reproductive toxicology (Elmsford, N.Y.) 20060201
Effect of methoxychlor and estradiol on cytochrome p450 enzymes in the mouse ovarian surface epithelium. Toxicological sciences : an official journal of the Society of Toxicology 20060201
Rapid effects of pesticides on human granulosa-lutein cells. Reproduction (Cambridge, England) 20060201
Perinatal exposure to endocrine disrupting compounds alters behavior and brain in the female pine vole. Neurotoxicology and teratology 20060101
A case for revisiting the safety of pesticides: a closer look at neurodevelopment. Environmental health perspectives 20060101
Regression analysis of pesticide use and breast cancer incidence in California Latinas. Journal of environmental health 20060101
Effects of chronic exposure to sodium arsenite on hypothalamo-pituitary-testicular activities in adult rats: possible an estrogenic mode of action. Reproductive biology and endocrinology : RB&E 20060101
Toxic effects of methoxychlor on the episodic prolactin secretory pattern: possible mediated effects of nitric oxide production. Journal of circadian rhythms 20060101
David Kupfer: a career retrospective. Drug metabolism reviews 20060101
David Kupfer, Ph.D. A mentor and a scientist. Drug metabolism reviews 20060101
Activated estrogens and antiestrogens: a 30-year journey with David Kupfer. Drug metabolism reviews 20060101
Pesticide exposure: the hormonal function of the female reproductive system disrupted? Reproductive biology and endocrinology : RB&E 20060101
Biodegradation of methoxychlor and its metabolites by the white rot fungus Stereum hirsutum related to the inactivation of estrogenic activity. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20060101
Identification of estrogen-regulated genes by microarray analysis of the uterus of immature rats exposed to endocrine disrupting chemicals. Reproductive biology and endocrinology : RB&E 20060101
Validation study of OECD rodent uterotrophic assay for the assessment of estrogenic activity in Sprague-Dawley immature female rats. Journal of toxicology and environmental health. Part A 20051210
Screening 31 endocrine-disrupting pesticides in water and surface sediment samples from Beijing Guanting reservoir. Chemosphere 20051201
Spatial trends and factors affecting variation of organochlorine contaminants levels in Canadian Arctic beluga (Delphinapterus leucas). The Science of the total environment 20051201
Methoxychlor inhibits brain mitochondrial respiration and increases hydrogen peroxide production and CREB phosphorylation. Toxicological sciences : an official journal of the Society of Toxicology 20051201
The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases. PLoS genetics 20051201
Seminiferous cord formation and germ-cell programming: epigenetic transgenerational actions of endocrine disruptors. Annals of the New York Academy of Sciences 20051201
Development of estrogen-responsive transgenic medaka for environmental monitoring of endocrine disrupters. Environmental science & technology 20051115
Methoxychlor directly affects ovarian antral follicle growth and atresia through Bcl-2- and Bax-mediated pathways. Toxicological sciences : an official journal of the Society of Toxicology 20051101
Comparison of relative binding affinities of endocrine active compounds to fathead minnow and rainbow trout estrogen receptors. Environmental toxicology and chemistry 20051101
Impact of maternal dietary exposure to endocrine-acting chemicals on progesterone receptor expression in microdissected hypothalamic medial preoptic areas of rat offspring. Toxicology and applied pharmacology 20051015
Are EDCs blurring issues of gender? Environmental health perspectives 20051001
Fundamental flaws of hormesis for public health decisions. Environmental health perspectives 20051001
Biomarker measurements in a coastal fish-eating population environmentally exposed to organochlorines. Environmental health perspectives 20051001
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. Journal of medicinal chemistry 20050908
Sulfonation of environmental chemicals and their metabolites in the polar bear (Ursus maritimus). Drug metabolism and disposition: the biological fate of chemicals 20050901
Long term dietary methoxychlor exposure in rats increases sodium solution consumption but has few effects on other sexually dimorphic behaviors. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050901
CAR and PXR: xenosensors of endocrine disrupters? Chemico-biological interactions 20050815
Methoxychlor-induced inducible nitric oxide synthase and proinflammatory cytokines expression in macrophages via NF-kappaB, ERK, and p38 mitogen-activated protein kinases. Biochemical and biophysical research communications 20050812
Methoxychlor disrupts uterine Hoxa10 gene expression. Endocrinology 20050801
Myelotoxicity in genistein-, nonylphenol-, methoxychlor-, vinclozolin- or ethinyl estradiol-exposed F1 generations of Sprague-Dawley rats following developmental and adult exposures. Toxicology 20050801
Consequences of endocrine disrupting chemicals on reproductive endocrine function in birds: establishing reliable end points of exposure. Domestic animal endocrinology 20050801
An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment. Environmental health perspectives 20050801
Endocrine-disrupting chemicals probed as potential pathways to illness. JAMA 20050720
Comparative in vitro metabolism of methoxychlor in male and female rats: metabolism of demethylated methoxychlor metabolites by precision-cut rat liver slices. Xenobiotica; the fate of foreign compounds in biological systems 20050701
Developmental biology. Endocrine disrupters trigger fertility problems in multiple generations. Science (New York, N.Y.) 20050603
Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science (New York, N.Y.) 20050603
Accurate prediction of the response of freshwater fish to a mixture of estrogenic chemicals. Environmental health perspectives 20050601
Effects of selected xenoestrogens on liver peroxisomes, vitellogenin levels and spermatogenic cell proliferation in male zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20050601
[Establishment of reporter gene-based assays for the identification of (anti) androgenic effects of chemicals in CHO cells]. Wei sheng yan jiu = Journal of hygiene research 20050501
[Distribution of organochlorine pesticides in surface sediments from Huangpu River and its risk evaluation]. Huan jing ke xue= Huanjing kexue 20050501
Assessing the consequences of the pesticide methoxychlor: neuroendocrine and behavioral measures as indicators of biological impact of an estrogenic environmental chemical. Brain research bulletin 20050415
D-amphetamine-related reinforcing effects are reduced in mice exposed prenatally to estrogenic endocrine disruptors. Brain research bulletin 20050415
Embryonic co-exposure to methoxychlor and Clophen A50 alters sexual behavior in adult male quail. Archives of toxicology 20050401
Urinary concentrations of bisphenol A and 4-nonylphenol in a human reference population. Environmental health perspectives 20050401
Comparative in vitro metabolism of the suspected pro-oestrogenic compound, methoxychlor in precision-cut liver slices from male and female rats. Xenobiotica; the fate of foreign compounds in biological systems 20050401
Organochlorine insecticides: impacts on human HepG2 cytochrome P4501A, 2B activities and glutathione levels. Toxicology in vitro : an international journal published in association with BIBRA 20050301
Necessity to measure PCBs and organochlorine pesticide concentrations in human umbilical cords for fetal exposure assessment. Environmental health perspectives 20050301
Acceleration of autoimmunity by organochlorine pesticides in (NZB x NZW)F1 mice. Environmental health perspectives 20050301
Organochlorine pesticides and mercury in cottonmouths (Agkistrodon piscivorus) from northeastern Texas, USA. Environmental toxicology and chemistry 20050301
Dietary methoxychlor exposure modulates splenic natural killer cell activity, antibody-forming cell response and phenotypic marker expression in F0 and F1 generations of Sprague Dawley rats. Toxicology 20050214
Methoxychlor induces proliferation of the mouse ovarian surface epithelium. Toxicological sciences : an official journal of the Society of Toxicology 20050201
Effects of environmental and natural estrogens on vitellogenin production in hepatocytes of the brown frog (Rana temporaria). Aquatic toxicology (Amsterdam, Netherlands) 20050118
High volume bioassays to assess CYP3A4-mediated drug interactions: induction and inhibition in a single cell line. Drug metabolism and disposition: the biological fate of chemicals 20050101
Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays. Toxicological sciences : an official journal of the Society of Toxicology 20050101
Interactions between CYP2C9 and CYP2C19 in reconstituted binary systems influence their catalytic activity: possible rationale for the inability of CYP2C19 to catalyze methoxychlor demethylation in human liver microsomes. Drug metabolism and disposition: the biological fate of chemicals 20050101
A comparison of in vitro and in vivo EDSTAC test battery results for detecting antiandrogenic activity. Toxicology and applied pharmacology 20050101
Lepidium meyenii (Maca) increases litter size in normal adult female mice. Reproductive biology and endocrinology : RB&E 20050101
Longitudinal assessment of PCBs and chlorinated pesticides in pregnant women from Western Canada. Environmental health : a global access science source 20050101
Residues of endosulfan and other selected organochlorine pesticides in farm areas of the Lower Fraser Valley, British Columbia, Canada. Journal of environmental quality 20050101
Estrogen regulation of testicular function. Reproductive biology and endocrinology : RB&E 20050101
Smoking and reproduction: the oviduct as a target of cigarette smoke. Reproductive biology and endocrinology : RB&E 20050101
The reported active metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane, inhibits testosterone formation by cultured Leydig cells from neonatal rats. Reproductive toxicology (Elmsford, N.Y.) 20050101
Biochemical characterization of the Arctic char (Salvelinus alpinus) ovarian progestin membrane receptor. Reproductive biology and endocrinology : RB&E 20050101
Biology and physiology of Calbindin-D9k in female reproductive tissues: involvement of steroids and endocrine disruptors. Reproductive biology and endocrinology : RB&E 20050101
Induction and inhibition of oocyte maturation by EDCs in zebrafish. Reproductive biology and endocrinology : RB&E 20050101
Identification of health hazards to rural population living near pesticide dump sites in Poland. International journal of occupational medicine and environmental health 20050101
A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides. Biochemical pharmacology 20041215
Endocrine disruption in adolescence: immunologic, hematologic, and bone effects in monkeys. Toxicological sciences : an official journal of the Society of Toxicology 20041201
Use of trout liver slices to enhance mechanistic interpretation of estrogen receptor binding for cost-effective prioritization of chemicals within large inventories. Environmental science & technology 20041201
Chitinase activity in the epidermis of the fiddler crab, Uca pugilator, as an in vivo screen for molt-interfering xenobiotics. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20041201
The effects of the reported active metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane, on testosterone formation by cultured Leydig cells from young adult rats. Reproductive toxicology (Elmsford, N.Y.) 20041101
Androgenic and estrogenic response of green mussel extracts from Singapore's coastal environment using a human cell-based bioassay. Environmental health perspectives 20041101
In vivo imaging of activated estrogen receptors in utero by estrogens and bisphenol A. Environmental health perspectives 20041101
Gene expression profiles in mammary gland of male rats treated with genistein and methoxychlor. Environmental toxicology and pharmacology 20041101
Evaluation of the developmental and reproductive toxicity of methoxychlor using an anuran (Xenopus tropicalis) chronic exposure model. Toxicological sciences : an official journal of the Society of Toxicology 20041001
Effect of methoxychlor on various life stages of Xenopus laevis. Toxicological sciences : an official journal of the Society of Toxicology 20041001
Posthatch methoxychlor exposure adversely affects reproduction of adult zebra finches, Taeniopygia guttata. Bulletin of environmental contamination and toxicology 20041001
Chlorobenzenes, chlorinated pesticides, coplanar chlorobiphenyls and other organochlorine compounds in Greenland biota. The Science of the total environment 20040920
Effects of natural and synthetic estrogens and various environmental contaminants on vitellogenesis in fish primary hepatocytes: comparison of bream (Abramis brama) and carp (Cyprinus carpio). Toxicological sciences : an official journal of the Society of Toxicology 20040901
Exposure of women to organochlorine pesticides in Southern Spain. Environmental research 20040901
Bayesian multivariate logistic regression. Biometrics 20040901
Estrogenic and toxic effects of methoxychlor on zebrafish (Danio rerio). Environmental toxicology and chemistry 20040901
Acute toxicity of sediment-sorbed endrin, methoxychlor, and endosulfan to Hyalella azteca and Chironomus tentans. Bulletin of environmental contamination and toxicology 20040901
Behavioral alterations in response to fear-provoking stimuli and tranylcypromine induced by perinatal exposure to bisphenol A and nonylphenol in male rats. Environmental health perspectives 20040801
Effects of methoxychlor exposure during perinatal period on reproductive function after maturation in rats. The Journal of reproduction and development 20040801
Interactive effects of p,p'-dichlorodiphenyldichloroethylene and methoxychlor on hormone synthesis in largemouth bass ovarian cultures. Environmental toxicology and chemistry 20040801
In vitro metabolism of [14C]methoxychlor in rat, mouse, Japanese quail and rainbow trout in precision-cut liver slices. Xenobiotica; the fate of foreign compounds in biological systems 20040801
A novel flexible approach for evaluating fixed ratio mixtures of full and partial agonists. Toxicological sciences : an official journal of the Society of Toxicology 20040701
Glucuronidation of the oxidative cytochrome P450-mediated phenolic metabolites of the endocrine disruptor pesticide: methoxychlor by human hepatic UDP-glucuronosyl transferases. Drug metabolism and disposition: the biological fate of chemicals 20040701
Organochlorine pesticides in chorioallantoic membranes of Morelet's crocodile eggs from belize. Journal of wildlife diseases 20040701
Methoxychlor-induced atresia in the mouse involves Bcl-2 family members, but not gonadotropins or estradiol. Biology of reproduction 20040601
Effect of three xenobiotic compounds on Glutathione S-Transferase in the clam Ruditapes decussatus. Aquatic toxicology (Amsterdam, Netherlands) 20040528
Sexually dimorphic basal water absorption at the isolated pelvic patch of Japanese tree frog, Hyla japonica. Journal of experimental zoology. Part A, Comparative experimental biology 20040501
Using a customized DNA microarray for expression profiling of the estrogen-responsive genes to evaluate estrogen activity among natural estrogens and industrial chemicals. Environmental health perspectives 20040501
Estimation of estrogenic and antiestrogenic activities of selected pesticides by MCF-7 cell proliferation assay. Archives of environmental contamination and toxicology 20040501
Methoxychlor-induced alterations in the histological expression of angiogenic factors in pituitary and uterus. Journal of molecular histology 20040501
Alteration of pituitary hormone-immunoreactive cell populations in rat offspring after maternal dietary exposure to endocrine-active chemicals. Archives of toxicology 20040401
Oxidative dechlorination of methoxychlor by ligninolytic enzymes from white-rot fungi. Chemosphere 20040401
Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells. Environmental health perspectives 20040401
Sensitivity of the immature rat uterotrophic assay to mixtures of estrogens. Environmental health perspectives 20040401
Cross-talk between endocrine-disrupting chemicals and cytokine signaling through estrogen receptors. Biochemical and biophysical research communications 20040312
Determination of organochlorine compounds in human biological samples by GC-MS/MS. Biomedical chromatography : BMC 20040301
Effects of methoxychlor, dieldrin and lindane on sea urchin fertilization and early development. Aquatic toxicology (Amsterdam, Netherlands) 20040225
Recombinant human estrogen, androgen and progesterone receptors for detection of potential endocrine disruptors. Analytical and bioanalytical chemistry 20040201
Enantioselective recognition of mono-demethylated methoxychlor metabolites by the estrogen receptor. Chemosphere 20040201
CYP2C subfamily, primarily CYP2C9, catalyses the enantioselective demethylation of the endocrine disruptor pesticide methoxychlor in human liver microsomes: use of inhibitory monoclonal antibodies in P450 identification. Xenobiotica; the fate of foreign compounds in biological systems 20040201
Organochlorinated compounds in Caspian Sea sediments. Marine pollution bulletin 20040101
Maternal concentration of polychlorinated biphenyls and dichlorodiphenyl dichlorethylene and birth weight in Michigan fish eaters: a cohort study. Environmental health : a global access science source 20040101
Preimplantation exposures of murine embryos to estradiol or methoxychlor change postnatal development. Reproductive toxicology (Elmsford, N.Y.) 20040101
Phytoestrogen genistein and its pharmacological interactions with synthetic endocrine-active compounds. Current pharmaceutical design 20040101
Endocrine disruption and cognitive function in adolescent female rhesus monkeys. Neurotoxicology and teratology 20040101
Carcinogen-metabolizing enzymes and insecticides. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20040101
Dual action of oestrogens on the mouse constitutive androstane receptor. The Biochemical journal 20031201
Endocrine disruptors induce cytochrome P450 by affecting transcriptional regulation via pregnane X receptor. Toxicology and applied pharmacology 20031115
Impact of dietary exposure to methoxychlor, genistein, or diisononyl phthalate during the perinatal period on the development of the rat endocrine/reproductive systems in later life. Toxicology 20031105
Distinct molecular conformations of the estrogen receptor alpha complex exploited by environmental estrogens. Cancer research 20031101
Phthalates, alkylphenols, pesticides, polybrominated diphenyl ethers, and other endocrine-disrupting compounds in indoor air and dust. Environmental science & technology 20031015
Determination of the estrogenic and antiestrogenic effects of environmental contaminants in chicken embryo hepatocyte cultures by quantitative-polymerase chain reaction. Environmental toxicology and chemistry 20031001
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor. Chemical research in toxicology 20031001
Determination of organochlorine pesticides in water using microwave assisted headspace solid-phase microextraction and gas chromatography. Journal of chromatography. A 20030919
Hepatic CYP1A, 2B, 2C, 2E and 3A regulation by methoxychlor in male and female rats. Toxicology letters 20030915
Isolation of four aquatic streptomycetes strains capable of growth on organochlorine pesticides. Bioresource technology 20030901
Fate and assessment of persistent organic pollutants in water and sediment from Minjiang River Estuary, Southeast China. Chemosphere 20030901
The OECD program to validate the rat uterotrophic bioassay: an overview. Environmental health perspectives 20030901
The OECD program to validate the rat uterotrophic bioassay. Phase 2: dose-response studies. Environmental health perspectives 20030901
The OECD program to validate the rat uterotrophic bioassay. Phase 2: coded single-dose studies. Environmental health perspectives 20030901
Effects of exogenous estrogenic agents on pubertal growth and reproductive system maturation in female rhesus monkeys. Toxicological sciences : an official journal of the Society of Toxicology 20030701
Estrogenic endocrine disruptive components interfere with calcium handling and differentiation of human trophoblast cells. Journal of cellular biochemistry 20030701
Evaluation of alternative tactics for management of insecticide-resistant horn flies (Diptera: Muscidae). Journal of economic entomology 20030601
Resistance status of house flies (Diptera: Muscidae) from southeastern Nebraska beef cattle feedlots to selected insecticides. Journal of economic entomology 20030601
Effect of organochlorine pesticides on maturation of starfish and mouse oocytes. Toxicological sciences : an official journal of the Society of Toxicology 20030501
Analysis of pesticides in water and sediment under different storage conditions using gas chromatography. Archives of environmental contamination and toxicology 20030501
Methoxychlor modifies the ultradian secretory pattern of prolactin and affects its TRH response. Medical science monitor : international medical journal of experimental and clinical research 20030501
The multidrug resistance-associated protein 1 transports methoxychlor and protects the seminiferous epithelium from injury. Toxicology letters 20030430
Environmental estrogens alter early development in Xenopus laevis. Environmental health perspectives 20030401
Inhibition of gonadotropin-induced oviposition and ovarian steroidogenesis in the African clawed frog (Xenopus laevis) by the pesticide methoxychlor. Aquatic toxicology (Amsterdam, Netherlands) 20030212
Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes. Archives of biochemistry and biophysics 20030101
Preimplantation mouse embryo development as a target of the pesticide methoxychlor. Reproductive toxicology (Elmsford, N.Y.) 20030101
[Contents of organochlorine pesticides in water, pore water and sediment in Minjiang River Estuary of China]. Huan jing ke xue= Huanjing kexue 20030101
Expression profiling of estrogenic compounds using a sheepshead minnow cDNA macroarray. EHP toxicogenomics : journal of the National Institute of Environmental Health Sciences 20030101
Effect of transient embryonic in vivo exposure to the endocrine disruptor methoxychlor on embryonic and postnatal testis development. Journal of andrology 20030101
Assessment of xenoestrogenic exposure by a biomarker approach: application of the E-Screen bioassay to determine estrogenic response of serum extracts. Environmental health : a global access science source 20030101
Animal models of ovarian cancer. Reproductive biology and endocrinology : RB&E 20030101
Enantioselective metabolism of the endocrine disruptor pesticide methoxychlor by human cytochromes P450 (P450s): major differences in selective enantiomer formation by various P450 isoforms. Drug metabolism and disposition: the biological fate of chemicals 20021201
Induction of oxidative stress in the rat testis after short-term exposure to the organochlorine pesticide methoxychlor. Archives of toxicology 20021201
Increases in mouse uterine heat shock protein levels are a sensitive and specific response to uterotrophic agents. Environmental health perspectives 20021201
An avian bioassay for environmental estrogens: the growth response of zebra finch (Taeniopygia guttata) chick oviduct to oral estrogens. Environmental toxicology and chemistry 20021201
Determination of estrogenic activity in landfill leachate by simplified yeast two-hybrid assay. Journal of environmental monitoring : JEM 20021201
A binary screening assay for pro-oestrogens in food: metabolic activation using hepatic microsomes and detection with oestrogen sensitive recombinant yeast cells. Food additives and contaminants 20021201
Effect of xenoestrogen exposure on the expression of cytochrome P450 isoforms in rainbow trout liver. Environmental toxicology and chemistry 20021101
Thymic atrophy induced by methoxychlor in rat pups. Toxicology letters 20021005
A comparison of the estrogenic potencies of estradiol, ethynylestradiol, diethylstilbestrol, nonylphenol and methoxychlor in vivo and in vitro. Aquatic toxicology (Amsterdam, Netherlands) 20021002
Effect of tolerance to insecticides on substrate penetration by Formosan subterranean termites (Isoptera: Rhinotermitidae). Journal of economic entomology 20021001
Metabolism of the endocrine disruptor pesticide-methoxychlor by human P450s: pathways involving a novel catechol metabolite. Drug metabolism and disposition: the biological fate of chemicals 20020901
Determination of organochlorine pesticides in seawater using liquid-phase hollow fibre membrane microextraction and gas chromatography-mass spectrometry. Journal of chromatography. A 20020830
Uterine responsiveness to estradiol and DNA methylation are altered by fetal exposure to diethylstilbestrol and methoxychlor in CD-1 mice: effects of low versus high doses. Toxicology and applied pharmacology 20020815
Analysis of pesticides and PCB congeners in serum by GC/MS with SPE sample cleanup. Toxicology letters 20020805
Methoxychlor may cause ovarian follicular atresia and proliferation of the ovarian epithelium in the mouse. Toxicological sciences : an official journal of the Society of Toxicology 20020801
Persistent chlorinated pesticides in fish and cattle fat and their implications for human serum concentrations from the Sene-Gambian region. Journal of environmental monitoring : JEM 20020801
Detection of estrogenic activity in sediment-associated compounds using in vitro reporter gene assays. The Science of the total environment 20020703
Effect of methoxychlor on the antioxidant system in mitochondrial and microsome-rich fractions of rat testis. Toxicology 20020701
Is exposure to endocrine disrupting compounds during fetal/post-natal development affecting the reproductive potential of farm animals? Domestic animal endocrinology 20020701
Enhancing effects of beta-estradiol 3-benzoate but not methoxychlor on the promotion/progression stage of chemically-induced mammary carcinogenesis in ovariectomized rats. Japanese journal of cancer research : Gann 20020701
Workshop report. Children as a special subpopulation: focus on immunotoxicity. Federal Institute for Health Protection of Consumers and Veterinary Medicine (BgVV), 15-16 November 2001, Berlin, Germany. Archives of toxicology 20020701
Relationship between estrogen receptor-binding and estrogenic activities of environmental estrogens and suppression by flavonoids. Bioscience, biotechnology, and biochemistry 20020701
Organochlorine pesticides directly regulate gonadotropin-releasing hormone gene expression and biosynthesis in the GT1-7 hypothalamic cell line. Molecular and cellular endocrinology 20020628
Thyroid toxicity due to subchronic exposure to a complex mixture of 16 organochlorines, lead, and cadmium. Toxicological sciences : an official journal of the Society of Toxicology 20020601
Methoxychlor alters the predator-prey relationship between dragonfly naiads and salamander larvae. Bulletin of environmental contamination and toxicology 20020601
Effects of primary exposure to environmental and natural estrogens on vitellogenin production in carp (Cyprinus carpio) hepatocytes. Toxicological sciences : an official journal of the Society of Toxicology 20020501
Effects of subchronic exposure to a complex mixture of persistent contaminants in male rats: systemic, immune, and reproductive effects. Toxicological sciences : an official journal of the Society of Toxicology 20020501
PCDDs/PCDFs, PCBs, and organochlorine pesticides in eggs of Eurasian sparrowhawks (Accipiter nisus), hobbies (Falco subbuteo), and northern goshawks (Accipiter gentilis) collected in the area of Berlin-Brandenburg, Germany. Archives of environmental contamination and toxicology 20020501
Comparative assessment of endocrine modulators with oestrogenic activity. II. Persistent organochlorine pollutants. Archives of toxicology 20020501
The hidden effect of estrogenic/antiandrogenic methoxychlor on spermatogenesis. Toxicology and applied pharmacology 20020415
Improvement of a two-stage carcinogenesis model to detect modifying effects of endocrine disrupting chemicals on thyroid carcinogenesis in rats. Cancer letters 20020408
Genistein and methoxychlor modulate the activity of natural killer cells and the expression of phenotypic markers by thymocytes and splenocytes in F0 and F1 generations of Sprague-Dawley rats. Toxicology 20020402
Modulation of mammary gland development in prepubertal male rats exposed to genistein and methoxychlor. Toxicological sciences : an official journal of the Society of Toxicology 20020401
Assessment of interactions of diverse ternary mixtures in an estrogen receptor-alpha reporter assay. Toxicology and applied pharmacology 20020401
Oral estrogen masculinizes female zebra finch song system. Hormones and behavior 20020301
Development of two androgen receptor assays using adenoviral transduction of MMTV-luc reporter and/or hAR for endocrine screening. Toxicological sciences : an official journal of the Society of Toxicology 20020301
Combined effects of dietary phytoestrogen and synthetic endocrine-active compound on reproductive development in Sprague-Dawley rats: genistein and methoxychlor. Toxicological sciences : an official journal of the Society of Toxicology 20020301
The pesticide methoxychlor disrupts the fusion of myoblasts into myotubes in skeletal muscle cell culture. Toxicology and applied pharmacology 20020301
Utility of a juvenile fathead minnow screening assay for detecting (anti-)estrogenic substances. Environmental toxicology and chemistry 20020201
Altered behaviors in male mice, male quail, and salamander larvae following early exposures to the estrogenic pesticide methoxychlor. Neurotoxicology and teratology 20020101
Ethological methods to study the effects of maternal exposure to estrogenic endocrine disrupters: a study with methoxychlor. Neurotoxicology and teratology 20020101
Endocrine disruption caused by two common pollutants at 'acceptable' concentrations. Neurotoxicology and teratology 20020101
Cognitive testing (delayed non-match to sample) during oral treatment of female adolescent monkeys with the estrogenic pesticide methoxychlor. Neurotoxicology and teratology 20020101
Methoxychlor stimulates the mouse lactoferrin gene promoter through a GC-rich element. Biochemistry and cell biology = Biochimie et biologie cellulaire 20020101
The effect of methoxychlor on the epididymal antioxidant system of adult rats. Reproductive toxicology (Elmsford, N.Y.) 20020101
The rat as a model in developmental immunotoxicology. Human & experimental toxicology 20020101
The pesticide methoxychlor given orally during the perinatal/juvenile period, reduced the spermatogenic potential of males as adults by reducing their Sertoli cell number. Reproduction, nutrition, development 20020101
Effect of methoxychlor on antioxidant system of goat epididymal sperm in vitro. Asian journal of andrology 20011201
Response of MCF-7 human breast cancer cells to some binary mixtures of oestrogenic compounds in-vitro. The Journal of pharmacy and pharmacology 20011101
Diet and organochlorine contaminants in women of reproductive age under 40 years old. Early human development 20011101
Analysis of organochlorine pesticides in human milk: preliminary results. Early human development 20011101
A repeated 28-day oral dose toxicity study of methoxychlor in rats, based on the 'enhanced OECD test guideline 407' for screening endocrine-disrupting chemicals. Archives of toxicology 20011101
Halogenated organic contaminants in sediments of the Havel and Spree rivers (Germany). Part 5 of organic compounds as contaminants of the Elbe river and its tributaries. Environmental science & technology 20011015
Insecticide susceptibility in Coptotermes formosanus and Reticulitermes virginicus (Isoptera: Rhinotermitidae). Journal of economic entomology 20011001
Differential gene expression in response to methoxychlor and estradiol through ERalpha, ERbeta, and AR in reproductive tissues of female mice. Toxicological sciences : an official journal of the Society of Toxicology 20010901
Effects of prenatal exposure to low doses of diethylstilbestrol, o,p'DDT, and methoxychlor on postnatal growth and neurobehavioral development in male and female mice. Hormones and behavior 20010901
Metabolic activation of bisphenol A by rat liver S9 fraction. Toxicological sciences : an official journal of the Society of Toxicology 20010801
Optimization of a yeast estrogen screen and its applicability to study the release of estrogenic isoflavones from a soygerm powder. Environmental health perspectives 20010701
Determination of pesticides in drinking water by micellar electrokinetic capillary chromatography. Electrophoresis 20010701
Assessing the biological potency of binary mixtures of environmental estrogens using vitellogenin induction in juvenile rainbow trout (Oncorhynchus mykiss). Environmental science & technology 20010615
Application of static liquid-phase microextraction to the analysis of organochlorine pesticides in water. Journal of chromatography. A 20010615
Mechanism of induction of cytochrome p450 enzymes by the proestrogenic endocrine disruptor pesticide-methoxychlor: interactions of methoxychlor metabolites with the constitutive androstane receptor system. Drug metabolism and disposition: the biological fate of chemicals 20010601
Description and evaluation of a short-term reproduction test with the fathead minnow (Pimephales promelas). Environmental toxicology and chemistry 20010601
Effects of nutrient loading and planktivory on the accumulation of organochlorine pesticides in aquatic food chains. Environmental toxicology and chemistry 20010601
Identification of selected hormonally active agents and animal mammary carcinogens in commercial and residential air and dust samples. Journal of the Air & Waste Management Association (1995) 20010401
Inhibition of basal and stimulated progesterone synthesis by dichlorodiphenyldichloroethylene and methoxychlor in a stable pig granulosa cell line. Reproduction (Cambridge, England) 20010301
Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens. Chemical research in toxicology 20010301
Environmental toxicant effects on neuroendocrine function. Endocrine 20010301
Assessment of the effects of metabolism on the estrogenic activity of xenoestrogens: a two-stage approach coupling human liver microsomes and a yeast estrogenicity assay. The Journal of pharmacology and experimental therapeutics 20010201
Effects of p-nonylphenol, methoxychlor, and endosulfan on vitellogenin induction and expression in sheepshead minnow (Cyprinodon variegatus). Environmental toxicology and chemistry 20010201
An in vitro reporter gene assay method incorporating metabolic activation with human and rat S9 or liver microsomes. Biochemical and biophysical research communications 20010112
Cell response endpoints enhance sensitivity of the immature mouse uterotropic assay. Reproductive toxicology (Elmsford, N.Y.) 20010101
Actions of the endocrine disruptor methoxychlor and its estrogenic metabolite on in vitro embryonic rat seminiferous cord formation and perinatal testis growth. Reproductive toxicology (Elmsford, N.Y.) 20010101
The diverse mechanism of action of dichlorodiphenyldichloroethylene (DDE) and methoxychlor in ovarian cells in vitro. Reproductive toxicology (Elmsford, N.Y.) 20010101
Differential estrogen receptor binding of estrogenic substances: a species comparison. The Journal of steroid biochemistry and molecular biology 20001115
Modifying effects of ethinylestradiol but not methoxychlor on N-ethyl-N-nitrosourea-induced uterine carcinogenesis in heterozygous p53-deficient CBA mice. Toxicological sciences : an official journal of the Society of Toxicology 20001101
Interaction of methoxychlor and related compounds with estrogen receptor alpha and beta, and androgen receptor: structure-activity studies. Molecular pharmacology 20001001
Estradiol and pesticide methoxychlor do not exhibit additivity or synergism in the reproductive tract of adult ovariectomized mice. Journal of toxicology and environmental health. Part A 20000728
Effect of methoxychlor administration to male rats on hepatic, microsomal iodothyronine 5'-deiodinase, form I. The Journal of pharmacology and experimental therapeutics 20000701
Estrogenic effects of organochlorine pesticides on uterine leiomyoma cells in vitro. Toxicological sciences : an official journal of the Society of Toxicology 20000401
A metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1, 1-trichloroethane, reduces testosterone biosynthesis in rat leydig cells through suppression of steady-state messenger ribonucleic acid levels of the cholesterol side-chain cleavage enzyme. Biology of reproduction 20000301
Differential interaction of the methoxychlor metabolite 2,2-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane with estrogen receptors alpha and beta. Endocrinology 19991201
Estrogen directly respresses gonadotropin-releasing hormone (GnRH) gene expression in estrogen receptor-alpha (ERalpha)- and ERbeta-expressing GT1-7 GnRH neurons. Endocrinology 19991101
Methoxychlor stimulates estrogen-responsive messenger ribonucleic acids in mouse uterus through a non-estrogen receptor (non-ER) alpha and non-ER beta mechanism. Endocrinology 19990801
Growth stimulation of a rat pituitary cell line MtT/E-2 by environmental estrogens in vitro and in vivo. Endocrine journal 19990801
Monospecific antipeptide antibody to cytochrome P-450 2B6. Drug metabolism and disposition: the biological fate of chemicals 19990401
Low-dose bioactivity of xenoestrogens in animals: fetal exposure to low doses of methoxychlor and other xenoestrogens increases adult prostate size in mice. Toxicology and industrial health 19990101
Methoxychlor given in the periimplantation period blocks sexual arousal in male mice. Reproductive toxicology (Elmsford, N.Y.) 19990101
Perinatal exposure to estrogenic compounds and the subsequent effects on the prostate of the adult rat: evaluation of inflammation in the ventral and lateral lobes. Reproductive toxicology (Elmsford, N.Y.) 19990101
Comparative estrogenic activity of wine extracts and organochlorine pesticide residues in food. Environmental health perspectives 19981201
Estrogenic xenobiotics increase expression of SS-A/Ro autoantigens in cultured human epidermal cells. Acta dermato-venereologica 19981101
Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology 19981001
Human cytochrome P450-catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen. Role of CYP2C19 and CYP1A2 in O-demethylation. Drug metabolism and disposition: the biological fate of chemicals 19980901
Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells. Toxicology and applied pharmacology 19980701
Prosubstrates of CYP3A4, the major human hepatic cytochrome P450: transformation into substrates by other P450 isoforms. Biochemical pharmacology 19980601
Identification of estrogen receptor beta2, a functional variant of estrogen receptor beta expressed in normal rat tissues. Endocrinology 19980301
Mechanism of induction of rat hepatic CYP2B and 3A by the pesticide methoxychlor. Journal of biochemical and molecular toxicology 19980101
Neonatal exposure to technical methoxychlor alters pregnancy outcome in female mice. Reproductive toxicology (Elmsford, N.Y.) 19980101
Xenobiotic interaction with and alteration of channel catfish estrogen receptor. Toxicology and applied pharmacology 19971201
The effects of perinatal/juvenile methoxychlor exposure on adult rat nervous, immune, and reproductive system function. Fundamental and applied toxicology : official journal of the Society of Toxicology 19971101
Influence of beta-naphthoflavone and methoxychlor pretreatment on the biotransformation and estrogenic activity of methoxychlor in channel catfish (Ictalurus punctatus). Toxicology and applied pharmacology 19970801
Examination of purported probes of human CYP2B6. Pharmacogenetics 19970601
Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay. Toxicology and applied pharmacology 19970301
Environmental xenobiotics may disrupt normal endocrine function by interfering with the binding of physiological ligands to steroid receptors and binding proteins. Environmental health perspectives 19970301
Catalytic characteristics of CYP3A4: requirement for a phenolic function in ortho hydroxylation of estradiol and mono-O-demethylated methoxychlor. Biochemistry 19970225
Estradiol or methoxychlor stimulates estrogen receptor (ER) expression in uteri. Reproductive toxicology (Elmsford, N.Y.) 19960101
Methoxychlor mimics the action of 17 beta-estradiol on induction of uterine epidermal growth factor receptors in immature female rats. Reproductive toxicology (Elmsford, N.Y.) 19960101
Cytochrome P450 catalyzed covalent binding of methoxychlor to rat hepatic, microsomal iodothyronine 5'-monodeiodinase, type I: does exposure to methoxychlor disrupt thyroid hormone metabolism? Archives of biochemistry and biophysics 19951001
Effects of estrogen, progesterone, and methoxychlor on surgically induced endometriosis in rats. Fundamental and applied toxicology : official journal of the Society of Toxicology 19950901
Estrogenic pesticides: binding relative to estradiol in MCF-7 cells and effects of exposure during fetal life on subsequent territorial behaviour in male mice. Toxicology letters 19950501
Induction of the hepatic CYP2B and CYP3A enzymes by the proestrogenic pesticide methoxychlor and by DDT in the rat. Effects on methoxychlor metabolism. Journal of biochemical toxicology 19950201
Neonatal exposures to technical methoxychlor alters ovaries in adult mice. Reproductive toxicology (Elmsford, N.Y.) 19950101
Methoxychlor regulates rat uterine estrogen-induced protein. Toxicology and applied pharmacology 19950101
Effects of methoxychlor on skin tumor development. Toxicology letters 19941201
Metabolism of the proestrogenic pesticide methoxychlor by hepatic P450 monooxygenases in rats and humans. Dual pathways involving novel ortho ring-hydroxylation by CYP2B. Drug metabolism and disposition: the biological fate of chemicals 19940101
Reversible and time-dependent inhibition of the hepatic cytochrome P450 steroidal hydroxylases by the proestrogenic pesticide methoxychlor in rat and human. Journal of biochemical toxicology 19931201
Substrate-binding region of cytochrome P-450SCC (P-450 XIA1). Identification and primary structure of the cholesterol binding region in cytochrome P-450SCC. Biochimica et biophysica acta 19930213
Influence of bromfenvinphos alone, and in mixture with methoxychlor, on levels of gamma-glutamyl transpeptidase, ceruloplasmin and cholesterol in the blood plasma of laboratory mice. Polish journal of pharmacology 19930101
Purified methoxychlor stimulates the reproductive tract in immature female mice. Reproductive toxicology (Elmsford, N.Y.) 19930101
Effect of methoxychlor on ovarian steroidogenesis: role in early pregnancy loss. Reproductive toxicology (Elmsford, N.Y.) 19930101
Endpoints of spermatotoxicity in the rat after short duration exposures to fourteen reproductive toxicants. Reproductive toxicology (Elmsford, N.Y.) 19920101
Effects of methoxychlor treatment of pregnant mice on female offspring of the treated and subsequent pregnancies. Reproductive toxicology (Elmsford, N.Y.) 19920101
Morphological and biochemical alterations in reproductive tracts of neonatal female mice treated with the pesticide methoxychlor. Biology of reproduction 19900301
Inhibitory effects of technical grade methoxychlor on development of neonatal male mouse reproductive organs. Biology of reproduction 19900301
A dose-response analysis of methoxychlor-induced alterations of reproductive development and function in the rat. Fundamental and applied toxicology : official journal of the Society of Toxicology 19890101
Effects of low subchronic doses of methoxychlor on the rat hypothalamic-pituitary reproductive axis. Toxicology and applied pharmacology 19861201
Role of hepatic monooxygenases in generating estrogenic metabolites from methoxychlor and from its identified contaminants. Molecular pharmacology 19850101
Interstitial cell carcinomas of the testis in Balb/C male mice ingesting methoxychlor. Journal of cancer research and clinical oncology 19790219
Bilateral sudden deafness following combined insecticide poisoning. The Laryngoscope 19780801
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Methoxychlor effects on hepatic storage of vitamin A in rats. Bulletin of environmental contamination and toxicology 19760801
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