Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).

Toxicological sciences : an official journal of the Society of Toxicology 20131201

Evaluation of in vitro cytochrome P450 induction and inhibition activity of deoxyelephantopin, a sesquiterpene lactone from Elephantopus scaber L.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20131001

Felodipine-diazabicyclo[2.2.2]octane-water (1/1/1).

Acta crystallographica. Section C, Crystal structure communications 20121101

Antihypertensive effect of low-frequency transcutaneous electrical nerve stimulation (TENS) in comparison with drug treatment.

Blood pressure 20121001

Optimizing the ability of PVP/PEG mixtures to be used as appropriate carriers for the preparation of drug solid dispersions by melt mixing technique using artificial neural networks: I.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120901

Mechanistic insights into the dissolution of spray-dried amorphous solid dispersions.

Journal of pharmaceutical sciences 20120801

QSAR model for human pregnane X receptor (PXR) binding: screening of environmental chemicals and correlations with genotoxicity, endocrine disruption and teratogenicity.

Toxicology and applied pharmacology 20120801

A mechanism-based approach for absorption modeling: the Gastro-Intestinal Transit Time (GITT) model.

The AAPS journal 20120601

Moringa coagulant as a stabilizer for amorphous solids: Part I.

AAPS PharmSciTech 20120601

Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.

Journal of medicinal chemistry 20120524

Microstructural investigation to the controlled release kinetics of monolith osmotic pump tablets via synchrotron radiation X-ray microtomography.

International journal of pharmaceutics 20120510

Enhancement of felodipine dissolution rate through its incorporation into Eudragit® E-PHB polymeric microparticles: in vitro characterization and investigation of absorption in rats.

Journal of pharmaceutical sciences 20120401

Use of clopidogrel and calcium channel blockers and risk of major adverse cardiovascular events.

European journal of clinical investigation 20120301

ToF-SIMS analysis of chemical heterogenities in inkjet micro-array printed drug/polymer formulations.

Journal of materials science. Materials in medicine 20120201

[Analysis and evaluation of the impurity of felodipine and its tablets].

Yao xue xue bao = Acta pharmaceutica Sinica 20120201

Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.

Bioorganic & medicinal chemistry letters 20120115

Role of cyclodextrin complexation in felodipine-sustained release matrix tablets intended for oral transmucosal delivery: in vitro and ex vivo characterization.

Pharmaceutical development and technology 20120101

Effect of felodipine with irbesartan or metoprolol on sexual function and oxidative stress in women with essential hypertension.

Journal of hypertension 20120101

Inkjet printing as a novel medicine formulation technique.

Journal of controlled release : official journal of the Controlled Release Society 20111210

Pharmacokinetic interaction involving sorafenib and the calcium-channel blocker felodipine in a patient with hepatocellular carcinoma.

Investigational new drugs 20111201

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

PLoS computational biology 20111201

Compositional analysis of low quantities of phase separation in hot-melt-extruded solid dispersions: a combined atomic force microscopy, photothermal fourier-transform infrared microspectroscopy, and localised thermal analysis approach.

Pharmaceutical research 20110901

Application of pharmaceutical QbD for enhancement of the solubility and dissolution of a class II BCS drug using polymeric surfactants and crystallization inhibitors: development of controlled-release tablets.

AAPS PharmSciTech 20110901

Development of a high-performance liquid chromatography method for simultaneous determination of pioglitazone and felodipine in pig serum: application to pharmacokinetic study.

Biomedical chromatography : BMC 20110801

Dissolution and precipitation behavior of amorphous solid dispersions.

Journal of pharmaceutical sciences 20110801

The stability of solid dispersions of felodipine in polyvinylpyrrolidone characterized by nanothermal analysis.

International journal of pharmaceutics 20110729

Development of bioadhesive buccal tablets for felodipine and pioglitazone in combined dosage form: in vitro, ex vivo, and in vivo characterization.

Drug delivery 20110701

Influence of particle size on the ultraviolet spectrum of particulate-containing solutions: implications for in-situ concentration monitoring using UV/Vis fiber-optic probes.

Pharmaceutical research 20110701

Acute angiotensin II receptor blockade improves insulin-induced microvascular function in hypertensive individuals.

Microvascular research 20110701

The effect of metoprolol alone and combined metoprolol-felodipin on the digital microcirculation of patients with primary Raynaud's syndrome.

Microvascular research 20110701

Cystic fibrosis: a new target for 4-Imidazo[2,1-b]thiazole-1,4-dihydropyridines.

Journal of medicinal chemistry 20110609

Is a systolic blood pressure target <140 mmHg indicated in all hypertensives? Subgroup analyses of findings from the randomized FEVER trial.

European heart journal 20110601

A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y12 receptor.

Bioorganic & medicinal chemistry letters 20110515

Development of push-pull osmotic tablets using chitosan-poly(acrylic acid) interpolymer complex as an osmopolymer.

AAPS PharmSciTech 20110301

Identification of clinically used drugs that activate pregnane X receptors.

Drug metabolism and disposition: the biological fate of chemicals 20110101

Pharmacokinetics of felodipine extended-release tablets in healthy Taiwanese subjects: a retrospective review.

Arzneimittel-Forschung 20110101

[Calcium channels blocker felodipin in the treatment of patients with arterial hypertension and chronic cardial failure with preserved cardiac output].

Terapevticheskii arkhiv 20110101

Pharmacokinetic and antihypertensive profile of amlodipine and felodipine-ER in younger versus older patients with hypertension.

Journal of cardiovascular pharmacology 20101201

Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Bioorganic & medicinal chemistry letters 20101101

[Therapeutic effect on essential hypertension treated with combined therapy of acupuncture and medication].

Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20101101

A thermal analysis method to predict the complete phase diagram of drug-polymer solid dispersions.

International journal of pharmaceutics 20101031

Effects of individual risk factors on the residual risk of cardiovascular events in a population of treated Chinese patients with hypertension: data from the Felodipine Event Reduction (FEVER) study.

Journal of hypertension 20101001

Biorelevant media to simulate fluids in the ascending colon of humans and their usefulness in predicting intracolonic drug solubility.

Pharmaceutical research 20101001

Antihypertensive and antiarrhythmic properties of a para-hydroxy[bis(ortho-morpholinylmethyl)]phenyl-1,4-DHP compound: comparison with other compounds of the same kind and relationship with logP values.

European journal of medicinal chemistry 20101001

Characterisation and prediction of phase separation in hot-melt extruded solid dispersions: a thermal, microscopic and NMR relaxometry study.

Pharmaceutical research 20100901

A novel method to measure the glass and melting transitions of pharmaceutical powders.

International journal of pharmaceutics 20100830

[Effect between felodipine plus irbesartan and felodipine plus metoprolol regimen on the sexual function in young and middle-aged women with hypertension].

Zhonghua xin xue guan bing za zhi 20100801

Selection of alternative CYP3A4 probe substrates for clinical drug interaction studies using in vitro data and in vivo simulation.

Drug metabolism and disposition: the biological fate of chemicals 20100601

Effect of felodipine on myocardial and renal injury induced by aldosterone-high salt hypertension in uninephrectomized rats.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20100501

Publication bias on clinical studies of pharmacokinetic interactions between felodipine and grapefruit juice.

Die Pharmazie 20100501

Effect of polymer hygroscopicity on the phase behavior of amorphous solid dispersions in the presence of moisture.

Molecular pharmaceutics 20100405

Understanding the behavior of amorphous pharmaceutical systems during dissolution.

Pharmaceutical research 20100401

Blockade of calcium channels and AT1 receptor prevents the hypertensive effect of calcilytic NPS 2143 in rats.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100401

A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle.

Proceedings of the National Academy of Sciences of the United States of America 20100223

Interaction between felodipine and bovine serum albumin: fluorescence quenching study.

Luminescence : the journal of biological and chemical luminescence 20100101

Effect of temperature and moisture on the miscibility of amorphous dispersions of felodipine and poly(vinyl pyrrolidone).

Journal of pharmaceutical sciences 20100101

Felodipine-induced eruptive telangiectasia following mastectomy and radiotherapy.

The British journal of dermatology 20100101

[Fixed combinations of antihypertensive medications--new opportunity in treatment of hypertension].

Lijecnicki vjesnik 20100101

[Calcium antagonists: on the way to expanding the indications].

Terapevticheskii arkhiv 20100101

[Comparative eficacy of antihypertensive therapy in patients with arterial hypertension and various sensitivity to salt].

Kardiologiia 20100101

Targeting the IL-6 dependent phenotype can identify novel therapies for cholangiocarcinoma.

PloS one 20100101

Effects of polymer type and storage relative humidity on the kinetics of felodipine crystallization from amorphous solid dispersions.

Pharmaceutical research 20091201

Synthesis of 4-thiophen-2'-yl-1,4-dihydropyridines as potentiators of the CFTR chloride channel.

Bioorganic & medicinal chemistry 20091201

Evaluation of drug-polymer miscibility in amorphous solid dispersion systems.

Pharmaceutical research 20091101

[Impact of antihypertensive medication timing on degree and stability of blood pressure lowering in patients with essential hypertension].

Zhonghua xin xue guan bing za zhi 20091101

Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.

Bioorganic & medicinal chemistry 20091001

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nature chemical biology 20091001

Mutation-specific potency and efficacy of cystic fibrosis transmembrane conductance regulator chloride channel potentiators.

The Journal of pharmacology and experimental therapeutics 20090901

[Effect of felodipine on the expression of NF-kappaB in rat model of atherosclerosis].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090901

Influence of grapefruit juice on the pharmacokinetics of diltiazem in Wistar rats upon single and multiple dosage regimens.

Die Pharmazie 20090801

Preparation of N-maleoylchitosan nanocapsules for loading and sustained release of felodipine.

Biomacromolecules 20090713

Extended release felodipine self-nanoemulsifying system.

AAPS PharmSciTech 20090601

Simulation of gastric lipolysis and prediction of felodipine release from a matrix tablet in the fed stomach.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090512

Pair distribution function X-ray analysis explains dissolution characteristics of felodipine melt extrusion products.

Journal of pharmaceutical sciences 20090401

Felodipine downregulates serum interleukin-18 levels in rats with fructose-induced metabolic syndrome.

Journal of endocrinological investigation 20090401

The calcium channel blocker felodipine attenuates the positive hemodynamic effects of the beta-blocker metoprolol in severe dilated cardiomyopathy--a prospective, randomized, double-blind and placebo-controlled study with invasive hemodynamic assessment.

International journal of cardiology 20090220

Chloride channels as drug targets.

Nature reviews. Drug discovery 20090201

[The use of felodipine in ambulatory practice: assessment of clinical efficacy and compliance in patients with arterial hypertension].

Kardiologiia 20090101

A cell-based assay for screening of antidotes to, and antivenom against Chironex fleckeri (box jellyfish) venom.

Journal of pharmacological and toxicological methods 20090101

From Tritace to Tri-Plen - the South African journey.

Cardiovascular journal of Africa 20090101

[Structural-functional properties of the vascular wall in hypertensive patients with coronary heart disease: effects of felodipin and perindopril].

Terapevticheskii arkhiv 20090101

Vasospasm-induced polymorphic ventricular tachycardia.

The Canadian journal of cardiology 20081201

Combination of amlodipine 10 mg and valsartan 160 mg lowers blood pressure in patients with hypertension not controlled by an ACE inhibitor/CCB combination.

Blood pressure. Supplement 20081201

[Curative effects on mild to moderate primary hypertension and influence on pulse wave velocity of slow releasing felodipine].

Zhonghua yi xue za zhi 20081118

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Journal of medicinal chemistry 20081113

Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.

Journal of medicinal chemistry 20081009

Effect of polymer type on the dissolution profile of amorphous solid dispersions containing felodipine.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20081001

Felodipine attenuates vascular inflammation in a fructose-induced rat model of metabolic syndrome via the inhibition of NF-kappaB activation.

Acta pharmacologica Sinica 20080901

Effect of poloxamer on the dissolution of felodipine and preparation of controlled release matrix tablets containing felodipine.

Archives of pharmacal research 20080801

Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid.

The Journal of biological chemistry 20080620

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Journal of medicinal chemistry 20080612

Effect and tolerability of felodipine ER (Feloten) in the treatment of hypertension assessed by office blood pressure and home blood pressure.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20080501

Ability of different polymers to inhibit the crystallization of amorphous felodipine in the presence of moisture.

Pharmaceutical research 20080401

Recrystallization of nifedipine and felodipine from amorphous molecular level solid dispersions containing poly(vinylpyrrolidone) and sorbed water.

Pharmaceutical research 20080301

Application of a self-modeling curve resolution method for studying the photodegradation kinetics of nitrendipine and felodipine.

Journal of pharmaceutical and biomedical analysis 20080213

Drug metabolism enzyme expression and activity in primary cultures of human proximal tubular cells.

Toxicology 20080203

Molecular mechanisms of felodipine suppressing atherosclerosis in high-cholesterol-diet apolipoprotein E-knockout mice.

Journal of cardiovascular pharmacology 20080201

Effects of extended-release felodipine on endothelial vasoactive substances in patients with essential hypertension.

Clinical chemistry and laboratory medicine 20080101

Felodipine reduces cardiac expression of IL-18 and perivascular fibrosis in fructose-fed rats.

Molecular medicine (Cambridge, Mass.) 20080101

[Efficacy of long acting calcium antagonist felodipine in smoking women with essential arterial hypertension].

Kardiologiia 20080101

[Efficacy, safety and tolerance of Felodipine controlled release tablets and Felodipine controlled release tablets associated combination therapy in the treatment of mild to moderate essential hypertension in China].

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20071218

Calorimetric study and modeling of molecular mobility in amorphous organic pharmaceutical compounds using a modified Adam-Gibbs approach.

The journal of physical chemistry. B 20071122

[Preparation of transdermal drug delivery system of felodipine-metoprolol and its bioavailability in rabbits].

Yao xue xue bao = Acta pharmaceutica Sinica 20071101

The influence of hydro-alcoholic media on hypromellose matrix systems.

Drug development and industrial pharmacy 20071001

Amorphous drug nanosuspensions. 3. Particle dissolution and crystal growth.

Langmuir : the ACS journal of surfaces and colloids 20070911

Competitive and cooperative effects of Bay K8644 on the L-type calcium channel current inhibition by calcium channel antagonists.

The Journal of pharmacology and experimental therapeutics 20070801

Combining SEM, TEM, and micro-Raman techniques to differentiate between the amorphous molecular level dispersions and nanodispersions of a poorly water-soluble drug within a polymer matrix.

International journal of pharmaceutics 20070801

Different roles of pummelo furanocoumarin and cytochrome P450 3A5*3 polymorphism in the fate and action of felodipine.

Current drug metabolism 20070801

Simultaneous determination of nitrendipine and one of its metabolites in plasma samples by gas chromatography with electron-capture detection.

Journal of pharmaceutical and biomedical analysis 20070727

Structure-activity relationship of 1,4-dihydropyridines as potentiators of the cystic fibrosis transmembrane conductance regulator chloride channel.

Molecular pharmacology 20070701

Investigation of the release mechanism of a sparingly water-soluble drug from solid dispersions in hydrophilic carriers based on physical state of drug, particle size distribution and drug-polymer interactions.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070601

The effect of ionizing radiation of 1,4-dihydropyridine derivatives in the solid state.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070501

Estimation of intragastric solubility of drugs: in what medium?

Pharmaceutical research 20070501

Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) study.

Circulation 20070417

Determination of gambogic acid in dog plasma by high-performance liquid chromatography for a pharmacokinetic study.

Biomedical chromatography : BMC 20070301

Lercanidipine in the treatment of hypertension.

The Annals of pharmacotherapy 20070301

The in vitro vascular effects of two chirodropid (Chironex fleckeri and Chiropsella bronzie) venoms.

Toxicology letters 20070110

Photophysics and photochemical studies of 1,4-dihydropyridine derivatives.

Photochemistry and photobiology 20070101

[The FEVER (Felodipine EVEnt Reduction) trial; a randomised, double-blind, placebo-controlled trial in Chinese hypertensive patients].

Vnitrni lekarstvi 20070101

Comparison in vitro felodipine release rate from the original versus generic product with controlled release of the drug.

Medicina (Kaunas, Lithuania) 20070101

[Effects of serotonin on reactivity of ocular vasculature].

Oftalmologia (Bucharest, Romania : 1990) 20070101

Influence of different polymers on the crystallization tendency of molecularly dispersed amorphous felodipine.

Journal of pharmaceutical sciences 20061201

Preparation of a solid dispersion of felodipine using a solvent wetting method.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20061001

A comparison of the physical stability of amorphous felodipine and nifedipine systems.

Pharmaceutical research 20061001

Theoretical and practical approaches for prediction of drug-polymer miscibility and solubility.

Pharmaceutical research 20061001

Additional antihypertensive effect of drugs in hypertensive subjects uncontrolled on diltiazem monotherapy: a randomized controlled trial using office and home blood pressure monitoring.

Clinical and experimental hypertension (New York, N.Y. : 1993) 20061001

Novel design of osmotic chitosan capsules characterized by asymmetric membrane structure for in situ formation of delivery orifice.

International journal of pharmaceutics 20060817

Application of PVP/HPMC miscible blends with enhanced mucoadhesive properties for adjusting drug release in predictable pulsatile chronotherapeutics.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060801

Effect of hydrogen bonding interactions on the release mechanism of felodipine from nanodispersions with polyvinylpyrrolidone.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060601

FEVER study: a trial further supporting the concept of a blood pressure-independent stroke protective effect by dihydropyridines.

Journal of hypertension 20060601

A small-molecule screen in C. elegans yields a new calcium channel antagonist.

Nature 20060504

Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Micronization and microencapsulation of felodipine by supercritical carbon dioxide.

Journal of microencapsulation 20060501

Effect of grapefruit juice in relation to human pharmacokinetic study.

Current clinical pharmacology 20060501

Felodipine nanodispersions as active core for predictable pulsatile chronotherapeutics using PVP/HPMC blends as coating layer.

International journal of pharmaceutics 20060426

Impaired capacity for stimulated fibrinolysis in primary hypertension is restored by antihypertensive therapy.

Hypertension (Dallas, Tex. : 1979) 20060401

A factorial study of combination hypertension treatment with metoprolol succinate extended release and felodipine extended release results of the Metoprolol Succinate-Felodipine Antihypertension Combination Trial (M-FACT).

American journal of hypertension 20060401

CACNA1C polymorphisms are associated with the efficacy of calcium channel blockers in the treatment of hypertension.

Pharmacogenomics 20060401

Initiation of hypertension treatment with a fixed-dose combination or its monocomponents -- does it really matter?

International journal of clinical practice 20060301

AT1 receptor antagonism improves endothelial dysfunction in postmenopausal women.

Maturitas 20060120

Sympatho-excitatory responses to once-daily dihydropyridines in young versus older hypertensive patients: amlodipine versus felodipine extended release.

Journal of hypertension 20060101

Hypertensive urgency.

Journal of clinical hypertension (Greenwich, Conn.) 20060101

Comparative study of barnidipine and felodipine in Chinese patients with essential hypertension.

The Journal of international medical research 20060101

A review of calcium channel antagonists in the treatment of pediatric hypertension.

Paediatric drugs 20060101

Thermal stability of 1,4-dihydropyridine derivatives in solid state.

Acta poloniae pharmaceutica 20060101

More heat to support aggressive blood pressure lowering: the FEVER study.

Journal of hypertension 20051201

The Felodipine Event Reduction (FEVER) Study: a randomized long-term placebo-controlled trial in Chinese hypertensive patients.

Journal of hypertension 20051201

Calcium channel antagonists and inhibition of human sphincter of Oddi contractions.

Scandinavian journal of gastroenterology 20051201

Impact of the intragastric location of extended release tablets on food interactions.

Journal of controlled release : official journal of the Controlled Release Society 20051128

Felodipine-metoprolol combination tablet: maintained health-related quality of life in the presence of substantial blood pressure reduction.

American journal of hypertension 20051001

Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.

Bioorganic & medicinal chemistry letters 20050915

Improved physicochemical characteristics of felodipine solid dispersion particles by supercritical anti-solvent precipitation process.

International journal of pharmaceutics 20050914

Dihydropyridines, felodipine, and PHARMAC.

The New Zealand medical journal 20050715

Felodipine-influenced gingival enlargement in an uncontrolled type 2 diabetic patient.

Journal of periodontology 20050701

Miscibility behavior and formation mechanism of stabilized felodipine-polyvinylpyrrolidone amorphous solid dispersions.

Drug development and industrial pharmacy 20050701

Prediction of genotoxicity of chemical compounds by statistical learning methods.

Chemical research in toxicology 20050601

Renoprotective therapy: is it blood pressure or albuminuria that matters?

Lancet (London, England) 20050301

Blood-pressure control for renoprotection in patients with non-diabetic chronic renal disease (REIN-2): multicentre, randomised controlled trial.

Lancet (London, England) 20050301

[The effect and mechanism of felodipine and valsartan on a novel salt-sensitive hypertensive rat induced by sensory denervation].

Zhonghua xin xue guan bing za zhi 20050301

Characteristics of felodipine-located poly(epsilon-caprolactone) microspheres.

Journal of microencapsulation 20050301

Comparison of the effects of valsartan and felodipine on plasma leptin and insulin sensitivity in hypertensive obese patients.

Hypertension research : official journal of the Japanese Society of Hypertension 20050301

Drug interactions with grapefruit juice.

Obstetrics and gynecology 20050201

Felodipine quantification in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050125

Effect of menthol on the pharmacokinetics and pharmacodynamics of felodipine in healthy subjects.

European journal of clinical pharmacology 20050101

Examination of 209 drugs for inhibition of cytochrome P450 2C8.

Journal of clinical pharmacology 20050101

Retrospective evaluation of a possible interaction between warfarin and levofloxacin.

Pharmacotherapy 20050101

[Toxicological analysis of selected 1,4-dihydropyridine calcium channel blockers in the diagnosis of intoxications].

Archiwum medycyny sadowej i kryminologii 20050101

Urinary excretion of aquaporin-2 after furosemide and felodipine in healthy humans.

Scandinavian journal of clinical and laboratory investigation 20050101

Ramipril/felodipine extended-release fixed-dose combination: a review of its use in the management of essential hypertension.

Drugs 20050101

Drug-associated gingival enlargement: case report and review of aetiology, management and evidence-based outcomes of treatment.

Journal of the New Zealand Society of Periodontology 20050101

Bergamottin contribution to the grapefruit juice-felodipine interaction and disposition in humans.

Clinical pharmacology and therapeutics 20041201

The effect of global brain ischemia in normal and diabetic animals: the influence of calcium channel blockers.

Endocrine 20041101

[Gingival hyperplasia and calcium antagonists].

Ugeskrift for laeger 20041018

6'7'-Dihydroxybergamottin contributes to the grapefruit juice effect.

Clinical pharmacology and therapeutics 20040601

Nelfinavir and felodipine: a cytochrome P450 3A4-mediated drug interaction.

Clinical pharmacology and therapeutics 20040401

The effect of Ca2+ channel antagonists on plasma concentrations of matrix metalloproteinase-2 and -9 in essential hypertension.

American journal of hypertension 20040301

Oxidation of Hantzsch 1,4-dihydropyridines of pharmacological significance by electrogenerated superoxide.

Pharmaceutical research 20040301

Determination of the lack of a drug interaction between azithromycin and warfarin.

Pharmacotherapy 20040201

[Nicergoline-induced Prinzmetal angina. 'Heartache' instead of headache].

Orvosi hetilap 20040104

Adherence to calcium channel blocker therapy in older adults: a comparison of amlodipine and felodipine.

The Journal of international medical research 20040101

[Efficacy and tolerability of felodipine based antihypertensive therapy in hospitalized patients with hypertension].

Kardiologiia 20040101

Calcium channel blockers (felodipine) and pediatric essential hypertension.

Current hypertension reports 20031201

Evaluation of a therapeutic conversion from amlodipine to felodipine.

Pharmacotherapy 20031101

Multisite kinetic analysis of interactions between prototypical CYP3A4 subgroup substrates: midazolam, testosterone, and nifedipine.

Drug metabolism and disposition: the biological fate of chemicals 20030901

Evaluation of polar lipid-hydrophilic polymer microparticles.

International journal of pharmaceutics 20030827

A comparative analysis of amlodipine and felodipine in a military outpatient population: efficacy, outcomes, and cost considerations.

Military medicine 20030701

Clinical trial of extended-release felodipine in pediatric essential hypertension.

Pediatric nephrology (Berlin, Germany) 20030601

Oxidized LDL and its compound lysophosphatidylcholine potentiate AngII-induced vasoconstriction by stimulation of RhoA.

Journal of the American Society of Nephrology : JASN 20030601

Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice.

Clinical pharmacology and therapeutics 20030601

Health economics in the Hypertension Optimal Treatment (HOT) study: costs and cost-effectiveness of intensive blood pressure lowering and low-dose aspirin in patients with hypertension.

Journal of internal medicine 20030401

Can the USP paddle method be used to represent in-vivo hydrodynamics?

The Journal of pharmacy and pharmacology 20030401

Short-versus long-term effects of different dihydropyridines on sympathetic and baroreflex function in hypertension.

Hypertension (Dallas, Tex. : 1979) 20030301

[The effect of analysed hypotensive drugs on certain metabolic parameters].

Polskie Archiwum Medycyny Wewnetrznej 20030301

Sensitive spectrophotometric determination of amlodipine and felodipine using iron(III) and ferricyanide.

Farmaco (Societa chimica italiana : 1989) 20030201

[Dangerous duo: hypertension and pre-diabetes--the underestimated risk].

MMW Fortschritte der Medizin 20030123

Different drug classes have variable effects on blood pressure depending on the time of day.

American journal of hypertension 20030101

The effect of nonsteroidal anti-inflammatory drugs on blood pressure in patients treated with different antihypertensive drugs.

Journal of clinical hypertension (Greenwich, Conn.) 20030101

In vitro release of felodipine from original brand and generic products.

Arzneimittel-Forschung 20030101

Comparative effect of lercanidipine, felodipine, and nifedipine GITS on blood pressure and heart rate in patients with mild to moderate arterial hypertension: the Lercanidipine in Adults (LEAD) Study.

Journal of clinical hypertension (Greenwich, Conn.) 20030101

[Severe felodipine and theophylline poisoning successfully treated by 4-aminopyridine: a case report].

Przeglad lekarski 20030101

Chitosan microparticle preparation for controlled drug release by response surface methodology.

Journal of microencapsulation 20030101

Safety and efficacy of therapeutically equivalent doses of sustained-release formulations of isradipine and felodipine.

Congestive heart failure (Greenwich, Conn.) 20030101

Pharmacodynamic interactions of levosimendan and felodipine in patients with coronary heart disease.

Cardiovascular drugs and therapy 20030101

Differential effects of once-daily antihypertensive drugs on blood pressure, left ventricular mass and sympathetic activity: Nifedipine-GITS versus felodipine-ER versus enalapril.

The Canadian journal of cardiology 20021201

Effects of aging and AT-1 receptor blockade on NO synthase expression and renal function in SHR.

Biochimica et biophysica acta 20021021

Evaluation of controlled-release polar lipid microparticles.

International journal of pharmaceutics 20020905

Evaluation of peppermint oil and ascorbyl palmitate as inhibitors of cytochrome P4503A4 activity in vitro and in vivo.

Clinical pharmacology and therapeutics 20020901

Acute effects of vasoactive drug treatment on brachial artery reactivity.

Journal of the American College of Cardiology 20020821

Dihydropyridines are not substitutable without careful monitoring.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20020801

[The effect and mechanism of felodipine on monocrotaline induced pulmonary hypertension in rats].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20020801

Angiotensin II type 1 receptor antagonism improves hypercholesterolemia-associated endothelial dysfunction.

Arteriosclerosis, thrombosis, and vascular biology 20020701

A comparison of candesartan, felodipine, and their combination in the treatment of elderly patients with systolic hypertension.

American journal of hypertension 20020601

Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

The Journal of biological chemistry 20020419

Effects of thyroid replacement therapy on arterial blood pressure in patients with hypertension and hypothyroidism.

American heart journal 20020401

Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4.

The Journal of pharmacology and experimental therapeutics 20020301

Calcium channel blockade with felodipine does not affect metabolic coronary vasodilation in patients with coronary artery disease.

Journal of cardiovascular pharmacology 20020201

A stability indicating LC method for felodipine.

Journal of pharmaceutical and biomedical analysis 20020201

Enantioselective determination of felodipine in human plasma by chiral normal-phase liquid chromatography and electrospray ionisation mass spectrometry.

Journal of pharmaceutical and biomedical analysis 20020115

Effect of felodipine on tacrolimus pharmacokinetics in a renal transplant recipient.

Transplantation 20020115

Felodipine inhibits nuclear translocation of p42/44 mitogen-activated protein kinase and human smooth muscle cell growth.

Cardiovascular research 20020101

Cutaneous drug reaction case reports: from the world literature.

American journal of clinical dermatology 20020101

Influence of hydrodynamics and particle size on the absorption of felodipine in labradors.

Pharmaceutical research 20020101

[Prospects of use of the combined preparation logimax in patients with essential hypertension].

Terapevticheskii arkhiv 20020101

Efficacy and safety of barnidipine compared with felodipine in the treatment of hypertension in Chinese patients.

The Journal of international medical research 20020101

IgA nephropathy in a patient with polycythemia vera. Clinical manifestation of chronic renal failure and heavy proteinuria.

American journal of nephrology 20020101

Smooth blood pressure control obtained with extended-release felodipine in elderly patients with hypertension: evaluation by 24-hour ambulatory blood pressure monitoring.

Drugs & aging 20020101

Preparation and characterization of drug-loaded polymethacrylate microspheres by an emulsion solvent evaporation method.

Journal of microencapsulation 20020101

Influence of antihypertensive treatment with perindopril, pindolol or felodipinon plasma leptin concentration in patients with essential hypertension.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020101

Deleterious effects of nifedipine on smooth muscle cells implies alterations of intracellular calcium signaling.

Fundamental & clinical pharmacology 20011201

The effects of an ACE inhibitor and a calcium antagonist on the progression of renal disease: the Nephros Study.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20011101

One-year study of felodipine or placebo for stage 1 isolated systolic hypertension.

Hypertension (Dallas, Tex. : 1979) 20011101

Photodistributed felodipine-induced facial telangiectasia.

Journal of the American Academy of Dermatology 20010801

Efficacy and safety of a therapeutic interchange from high-dose calcium channel blockers to a fixed-dose combination of amlodipine/benazepril in patients with moderate-to-severe hypertension.

Journal of human hypertension 20010801

Reduction in diastolic blood pressure and cardiovascular mortality in nondiabetic hypertensive patients. A reanalysis of the HOT study.

Arquivos brasileiros de cardiologia 20010801

Polymorphism of racemic felodipine and the unusual series of solid solutions in the binary system of its enantiomers.

Journal of pharmaceutical sciences 20010701

[Felodipine in hypertensive patients with mild encephalopathies].

Deutsche medizinische Wochenschrift (1946) 20010511

Investigation of the felodipine glassy state by atomic force microscopy.

International journal of pharmaceutics 20010507

Efficacy and safety of losartan/hydrochlorothiazide in patients with severe hypertension.

The American journal of cardiology 20010315

Mechanism of CGRP-induced relaxation in rat intramural coronary arteries.

British journal of pharmacology 20010301

[Letter concerning the article by E.C.Bornhövd, E.Schuller, T.Bieber, A.Wollenberg: 'Immunosuppressive macrolides and their use in dermatology'. Der Hautarzt (2000) 51:646-654].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20010301

Normal-phase TLC separation of enantiomers of 1.4-dihydropyridine derivatives.

Drug development and industrial pharmacy 20010201

Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins.

Clinical pharmacology and therapeutics 20010101

Comparison of the time courses and potencies of the vasodilator effects of nifedipine and felodipine in the human forearm.

Blood pressure 20010101

A randomised trial to compare the efficacy and safety of Felodipine (Plendil) and Nifedipine (Adalat) retard in patients with mild-to-moderate hypertension.

West African journal of medicine 20010101

Stroke precipitated by moderate blood pressure reduction.

The Journal of emergency medicine 20001101

Losartan: a review of its use, with special focus on elderly patients.

Drugs & aging 20000301

Low Dose Combination Therapy vs. High Dose Monotherapy in the Management of Hypertension.

Journal of clinical hypertension (Greenwich, Conn.) 19991101

Improved tolerability of felodipine compared with amlodipine in elderly hypertensives: a randomised, double-blind study in 535 patients, focusing on vasodilatory adverse events. The International Study Group.

International journal of clinical practice 19980901

Significance of blood pressure levels achieved with felodipine anti-hypertensive treatment on cardiovascular structure and function changes.

Journal of human hypertension 19980701

A comparison of nisoldipine coat-core and felodipine in the treatment of mild-to-moderate hypertension.

International journal of clinical practice 19980601

Benazepril versus felodipine as supplement to bendroflumethiazide: evaluation by office and ambulatory blood pressure.

Blood pressure monitoring 19980401

Prevention of left ventricular hypertrophy by ACE-inhibitor, ramipril in comparison with calcium-channel antagonist, felodipine.

International journal of cardiology 19980131

Influence of felodipine on experimental seizures and activity of different antiepileptic drugs in mice.

Polish journal of pharmacology 19980101

Effect of the calcium antagonist felodipine as supplementary vasodilator therapy in patients with chronic heart failure treated with enalapril: V-HeFT III. Vasodilator-Heart Failure Trial (V-HeFT) Study Group.

Circulation 19970805

Verapamil accelerates the transition to heart failure in obese, hypertensive, female SHHF/Mcc-fa(cp) rats.

Journal of cardiovascular pharmacology 19970601

Cardiovascular effects of a low-dose combination of ramipril and felodipine in spontaneously hypertensive rats.

British journal of pharmacology 19970501

Calcium antagonists, a useful additional therapy in treatment resistant hypertension: comparison of felodipine ER and nifedipine Retard by 24-h ambulatory blood pressure monitoring.

The Netherlands journal of medicine 19970101

Felodipine in the treatment of severe refractory hypertension.

Journal of human hypertension 19960901

Losartan potassium: a review of its pharmacology, clinical efficacy and tolerability in the management of hypertension.

Drugs 19960501

Does prophylactic treatment with felodipine, a calcium antagonist, prevent low-osmolar contrast-induced renal dysfunction in hydrated diabetic and nondiabetic patients with normal or moderately reduced renal function?

Scandinavian journal of urology and nephrology 19960201

Global efficacy and tolerability of losartan, an angiotensin II subtype 1-receptor antagonist, in the treatment of hypertension.

Blood pressure. Supplement 19960101

Safety and tolerability of losartan compared with atenolol, felodipine and angiotensin converting enzyme inhibitors.

Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19950701

Safety and tolerability of losartan potassium, an angiotensin II receptor antagonist, compared with hydrochlorothiazide, atenolol, felodipine ER, and angiotensin-converting enzyme inhibitors for the treatment of systemic hypertension.

The American journal of cardiology 19950415

Isradipine. An update of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the treatment of mild to moderate hypertension.

Drugs 19950401

Mono- and combination therapy with felodipine or enalapril in elderly patients with systolic hypertension.

Blood pressure 19940301

Efficacy and tolerability of extended-release felodipine and extended-release nifedipine in patients with mild-to-moderate essential hypertension.

Clinical therapeutics 19940101

Comparison of effects of felodipine versus hydrochlorothiazide on arterial diameter and pulse-wave velocity in essential hypertension.

The American journal of cardiology 19931001

General toxicity of the new calcium antagonist felodipine in dogs.

Arzneimittel-Forschung 19930701

A multicenter comparison of isradipine and felodipine in the treatment of mild-to-moderate hypertension. The Physician's Study Group.

American journal of hypertension 19930301

Long-term effects of felodipine in patients with reduced renal function.

Kidney international. Supplement 19920501

Felodipine clinical pharmacokinetics.

Clinical pharmacokinetics 19911201

Felodipine: a new dihydropyridine calcium-channel antagonist.

DICP : the annals of pharmacotherapy 19911101

Beta-adrenergic receptors and reflex tachycardia after single and repeated felodipine administration in essential hypertension.

Journal of cardiovascular pharmacology 19910601

Felodipine in combination with a beta-adrenoceptor blocker as an effective substitute for triple therapy in severe hypertension. The Australian Felodipine Multicentre Study Group.

European journal of clinical pharmacology 19910101

Extended release felodipine in essential hypertension. Variations in blood pressure during whole-day continuous ambulatory recording.

American journal of hypertension 19910101

Acute effects on exercise tolerance of felodipine and diltiazem, alone and in combination, in stable effort angina.

European heart journal 19910101

Felodipine ER formulation in the treatment of mild hypertension: efficacy and tolerability vs placebo.

British journal of clinical pharmacology 19901001

The influence of infusion rate on the hemodynamic effects of felodipine.

Clinical pharmacology and therapeutics 19900901

The efficacy and tolerability of long-term felodipine treatment in hypertension. The Scandinavian Multicenter Group.

Cardiovascular drugs and therapy 19900601

Cardiovascular-risk reduction: initial diuretic therapy compared with calcium-antagonist (felodipine) therapy for primary hypertension.

The Medical journal of Australia 19890904

Felodipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension.

Drugs 19881001

Antihypertensive effect of felodipine or hydralazine when added to beta-blocker therapy.

Journal of cardiovascular pharmacology 19880701

A double-blind comparison of felodipine and hydrochlorothiazide added to metoprolol to control hypertension.

European journal of clinical pharmacology 19880101

Catecholamines, renin-angiotensin-aldosterone, and cardiovascular response during exercise following acute and long-term calcium antagonism with felodipine in essential hypertension.

Journal of cardiovascular pharmacology 19871001

Monotherapy with felodipine, a new calcium antagonist, in mild and moderate hypertension.

Journal of cardiovascular pharmacology 19870101

Felodipine, a new calcium antagonist, as monotherapy in mild or moderate hypertension. Cooperative study group.

Drugs 19870101

Baroreflex control of renin release in spontaneously hypertensive rats after administration of felodipine.

Drugs 19870101

Felodipine compared to nifedipine as 'third-line drug' in resistant hypertension.

Angiology 19861101

Renal and antihypertensive effects of felodipine in hypertensive patients.

Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19851201

Felodipine can replace minoxidil in the treatment of refractory hypertension.

Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19851201

Renal and cardiovascular effects of acute and chronic administration of felodipine to SHR.

European journal of pharmacology 19850711

Antihypertensive effect of felodipine combined with beta-blockade. A comparison between 2 and 3 daily dosages.

Drugs 19850101

Comparative trial of felodipine and nifedipine in refractory hypertension.

Drugs 19850101

Effects of felodipine on resistance and capacitance vessels in patients with essential hypertension.

Drugs 19850101

Haemodynamic effects of single-dose felodipine in normal man.

Drugs 19850101

Hemodynamic effects of felodipine at rest and during exercise in exertional angina pectoris.

The American journal of cardiology 19830901